bone grafts used in nasal reconstruction

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Presenter Dr. Pulkit Agarwal

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Presenter – Dr. Pulkit Agarwal

INTRODUCTION Nasal surgery involves a wide spectrum of

procedures ranging from cosmetic rhinoplasty to

total nasal reconstruction.

Reconstruction of the nasal skeletal framework

is frequently necessary in patients like with

congenital or traumatic deformities.

This support is best obtained using bone or

cartilage.

HISTORY VON WALTER (1821) – Autogenous Bone Graft

Autogenous corticocancellous bone grafts to

reconstruct lost parts of the maxillofacial

skeleton.

These grafts can be used to augment the

severely atrophic edentulous alveolar ridges,

to reconstruct alveolar defects in cleft palate

patients, or to bridge defects that are the result

of ablative surgery or trauma.

Autogenous bone grafts, when adequately fixed,usually adapt to the recipient site and incorporatewell into the defects.

A layer of connective tissue will cover the graftswhile from the interface between the recipient boneand the graft revascularization takes place ultimatelyleading to the formation of new bone.

Fresh autografts contain surviving cells andinductive proteins, which can stimulate osteogenesis.

Autogenous grafts considered best as :

Nonimmunogenic

Partially retains its viability immediately aftertransplantation

WHY ALTERNATIVES ????

Limited availability

The sometimes unpredictable resorption

The need for a second operation site

The time consuming procedure

Donor site morbidity

The quantity of bone available

Increased costs of hospitalization

MECHANISMS OF BONE GRAFT HEALING

Many factors influence healing process, which mayalso be considered as a kind of bone regeneration.

Factors like :

Bone metabolism

Changes in hormonal balance

External influences that are present for a prolongedtime.

Revascularization is mandatory for graft healing asnewly formed blood vessels enable nutrients andhumoral substances to be brought into the graft.

MECHANISMS OF BONE HEALING

If revascularization is successful new bone is formedaround the transformed osteocytes at the margins of thegraft and the old bone is slowly replaced.

This process is called ‘Creeping Substitution’

WHICH TYPE OF BONE IS SUPERIOR ???

Cancellous bone – Easy capillary penetration.

Cortical bone – Volumetric maintainence.

So Corticocancellous bone is best.

Differences in healing between severalcorticocancellous donor sites are related to the 3Dosseous architecture ( The Cortical / Cancellous ratio)

TYPES OF GRAFT MATERIAL Per definition there are five types of grafts, i.e.

1. Autografts

2. Isografts

3. Allografts

4. Alloplasts

5. Xenografts

The term autograft refers to tissue transplanted from

one site to another within the same individual.

It can be cortical, cancellous or corticocancellous.

Most common sites for corticocancellous grafts areTypical donor sites are rib, iliac crest, fibula or radius,elbow, mastoid whereas oral sites include chin,retromolar area and mandibular body.

Allografts are obtained from cadavers or livingindividuals from the same species. In human medicinethey can be obtained from tissue banks (KÜBLER1997).

There are three types of bone allograft available:

Fresh or fresh-frozen bone

Freeze-dried bone allograft (FDBA)

Demineralized Freeze Dried Bone Allograft (DFDBA)

The most commonly used allograft is DFDBA.

Demineralized bone matrix minimises antigenicity.

Because allografts are not osteogenic, bone formation

takes longer and results in less volume compared to

autogenous grafts .

They revascularize quickly but the risk of an antigen

transmission, especially in a high vascular area as the

facial skeleton, increases the risk of rejection of the

graft.

So in oral and maxillofacial area demineralized bone

grafts can be used after irradiation.

Alloplasts are synthetic materials consisting of

biological inert substances. (eg Tricalciumphosphate

and Hydroxyapatite, Bovine Bone Mineral (BBM),

Coralline, Active glass ceramics).

Xenografts are composed of tissue taken from another

species (i.e. from an animal source, usually bovine).

The term ‘composite graft’ refers to grafts that are

composed of materials from different origins,

usually autogenous bone mixed with other

materials

CHARACTERISTICS OF THE IDEAL GRAFT MATERIAL

Nonimmunogenic

The shape and size of material is stable over time.

The material is reasonably malleable to carve or mold

into the desired shape.

The material does not cause discoloration or

transillumination of the intervening tissue.

The material is pliable.

The material is easily obtainable.

An adequate supply of the material is available.

Minimum donor site morbidity

Aetiology of Saddle Nose deformity

which may necessiate

Bone grafting for

augmentation

BONE GRAFTS USED FOR NASAL RECONSTRUCTION

NASAL BONE :

Small pieces of nasal bone may be removed during the

course of traditional rhinoplasty and can be re

implanted as a graft.

A particularly good use for this bone is as a graft to

bone gaps at the lateral osteotomies.

HIP BONE GRAFTS :

Less popular as bone tends to shrink (due to lack of

density of bone which inturn is helpful in carving it).

Other problem being painful donor site.

CALVARIAL BONE GRAFTS :

Very Dense

Used most commonly for nasal reconstruction.

The skull is formed from two layers of bone which are

separated by a type of marrow.

The outer layer may be removed and used for grafting.

It is possible to cause a fracture of the skull and there

is a remote chance of damage to the underlying brain.

Not recommended after 50 yrs age as outer layer fuses

with inner due to disappearance of marrow.

RIB BONE :

Commonly used.

Hard outer cortical layer used for grafting.

Problems include :

Ribs are curved.

Painful donor site

Scar on chest.

OLECRANON BONE GRAFT :

The bone is not particularly dense but the small

quantity that would be harvested is likely to persist in

the nose longer than a block of very porous

(cancellous) bone from within the hip bone.

This scar and minor bone deformity at the elbow are

very acceptable.

RADIAL BONE GRAFT :

BONE GRAFT FROM THE JAWS :

If small amount of bone required.

Ramus Graft – from area of wisdom tooth.

Tuberosity graft – from the posterior part of the upper

jaw behind the last molars.

Chin Grafts

Bone is harvested and placed immediately to the

required site where it is secured into place using small

screws, which will be removed at a later date.

Can be done under LA or intravenous sedation.

TIBIAL BONE GRAFT

Tibial bone graft is often used for sinus lift procedures

rather than nasal augmentation.

One can expect some discomfort at the surgical site for

a period of days or sometimes a week or two, though

walking is not restricted.

This surgery can be done as an outpatient at a surgical

facility.

MASTOID BONE GRAFT

Provides adequate autologous bone in most cases of

primary or revision rhinoplasty.

The donor site carries low morbidity and a well

camouflaged scar.

It is easily accessible.

SADDLE NOSE DEFORMITY RECONSTRUCTION WITH A SPLIT CALVARIAL BONE L-SHAPED STRUT

SURGICAL TECHNIQUE :

HARVESTING AND FASHIONING OF GRAFT :

Scalp incision is made along the superior rim of the temporalis

muscle in the nondominant temporoparietal region.

A trifurcated incision is then created, extending the incision

inferiorly within the hairline to the preauricular sulcus.

Dissection in the subgaleal plane is performed, and the

periosteum is incised 1.5 cm inferior to the scalp incision.

The periosteum is then elevated off the calvarial bone in this

region. A 6-mm round cutting bur is used to circumferentially

isolate a piece of outer table cortex.

Drilling is continued down to the level of the diploic bone.

A curved sagittal saw and curved osteotome are used to lift

the outer cortex free from the intact calvarium.

Bone wax is applied as necessary for hemostasis. The

periosteum is then closed using polyglactin 910 (Vicryl)

sutures, and the scalp is closed using subdermal 4-0

polyglactin 910 sutures and 4-0 chromic locking skin

sutures.

A suction drain is placed in the subgaleal layer and is

removed on postoperative day 1. The bone graft is divided

into 2 pieces that are used to construct a dorsal onlay graft

and columellar strut. The dimensions of each are based on

the ideal nasal length and projection.5,6 The dorsal piece is

contoured using 3- and 4-mm coarse and fine diamond burs

to recreate the concavity of the natural dorsum.

The cortical side is placed superficially, and the cancellous

side is placed deep.

The cephalic- most portion of the dorsal piece is thinned

and beveled to enable a smooth transition with the patient’s

intact bony nasal bridge. In addition, the dorsal piece is

beveled laterally to prevent a noticeable ridge.

The 2 pieces are fastened together using a 1-mm titanium

screw, in contrast to previously described tongue-in-groove

techniques. The L-shaped strut is then ready for

implantation

PLACEMENT OF THE L-SHAPED STRUT

The nasal skeleton is exposed using an external

rhinoplasty approach through an inverted-V columellar

incision with intravestibular marginal incisions.

Dissection is carried cephalically to the nasal dorsum. A

small portion of the nasal root is filed down to enable

smoother placement of the dorsal portion of the L-shaped

strut.

This also creates a “raw” bony surface for direct bone-to

bone contact, which hypothetically would enhance

osseous integration and fusion of the bone graft.

The medial crura of the lower lateral cartilages are

separated to enable placement of the caudal portion of the

graft into a secure pocket. In a manner akin to the

placement of a columellar strut, the bone graft is placed

into a secure pocket between the medial crura.

The base of the L shaped strut rests on the pre maxilla and

is secured with a transcrural suture. Once the L-shaped strut

is positioned in place, the lower lateral cartilages are

advanced over the caudal portion and vertex of the L-

shaped strut using intradomal sutures.

Two wire-pass drill holes are made in the dorsal bone to

place anchoring sutures to fix the lower lateral cartilages in

position and maintain the midline position of the graft. The

skin and soft-tissue nasal envelope is then closed.

CREATION OF OSTEOTOMIES

If osteotomies are necessary, a No. 11 blade is used to

create stab incisions in the cheek-nose junction bilaterally

to access the lateral rim of the bony nasal pyramid.

Medial and lateral osteotomies are then created near the

nasal bone midline and the nasofacial groove, respectively.

DRESSING

Contour taping is placed immediately after closure to shape

the external structure of the nose. A 1-piece standard porous

cast (ThermaSplint; Whitehall Manufacturing, City of

Industry, California) is placed superficial to the tape. The

cast and tape are removed 1 week postoperatively.

RADIAL BONE GRAFT FOR SEPTAL CORRECTION

Anaesthesia preferred – GA.

After local anaesthetic infiltration the nasal structures wereexposed through an open rhinoplasty approach.

Following hump resection, the septum was dissectedsubperichondrially and resected leaving a 0.8 to 1-cmdorsal and caudal L-strut.

Deviated caudal segment of the septal cartilage wasstraightened medialized and secured to the periosteum ofthe anterior nasal spine.

Radial bone graft was accessed from the lateral antecubitalregion, and bone graft was harvested from the lateral sideof radial bone.

Radial bone is triangular in cross section. The anterior and

posterior surfaces of the radius are generally smooth, whereas an

oval roughening for the attachment of pronator teres marks

approximatelly the middle of the lateral surface of the radius.

Bone graft was harvested a segment (about 5×1 cm) located

between the insertion of the pronator teres and the

brachioradialis muscles.

Lateral antecubital nerve, flexor and extensor muscles were

protected during bone graft harvesting procedure.

Bone graft was thinned by bone filing and shaped in the form of

a L-strut as "key in the keyhole pattern”.

The dorsal strut was placed by tongue in groove technique on the anterior nasal spine. L-strut frame was sutured under the upper lateral cartilage remnants and between the domes of two lower lateral cartilages to hide palpable edges and secure it in place.

Lateral and median osteotomies were also performed if

bony pyramid was also deviated.

Any residual irregularities on the dorsum were camouflaged

with Erol's Turkish delight.

Tipplasty was performed if necessary. Following closure,

nasal packing and plaster cast were applied. A plaster cast

was also applied on the forearm and removed 1 week later.

The packing and the nasal splint were removed at 4th and

7th days, respectively.

OLECRANON BONE GRAFT

SURGICAL PROCEDURE FOR GRAFT REMOVAL

The non-dominant forearm was chosen for removal of the

olecranon bone graft.

The proximal third of the posterior face was infiltrated followed

by a longitudinal incision and dissection of the planes.

The cortex of the olecranon was measured according to the

nasal defect for repair and the graft was removed with a bone

saw or a simple chisel.

Upon removal, the olecranon was placed in a container with

saline solution and the donor area was covered with bone wax.

Synthesis was carried out by planes, with absorbable sutures and

of skin with 4.0 nylon intradermal threads.

Finally, the limb was covered with a crepe bandage. A tourniquet

was not necessary. The graft was transferred into the recipient

area with external anchoring with micropore tape for 21 days;

rigid fixation was not used.

Possible graft resorption was monitored by anthropometric

measurements of the nose with photographic documentation and

graft radiological control.

Patients reported temporary paresthesia in the forearm scar

(donor area), with a complete recovery within 1 year.

The olecranon bone graft proved to be a good option for primary

or secondary rhinoplasty for the treatment of “saddle-back”

nose. Long-term resorption or morbidity of the donor area has

not been observed so far. This procedure ensures satisfactory,

predictable, and long-lasting aesthetic results

AUGMENTATION OF NASAL TIP PROJECTION USING

THE INFERIOR TURBINATE

GRAFT HARVEST AND PREPARATION

Inferior partial turbinectomy is performed in standard fashion,

following decongestion.

After careful infracture with a freer elevator, a right-angled

scissor is used to resect the anterior head or two-thirds of the

turbinate, including bone and soft tissue. After careful extraction

from the nose, the soft tissue covering the turbinate bone is

removed using iris scissors or a No. 15 blade, taking care to

avoid trauma to the turbinate bone.

The size of the implant will vary depending on the patient's

degree of bony inferior turbinate hypertrophy. The graft is then

shaped using a Mayo scissor. Hemostasis of the cut end of the

turbinate is achieved using suction electrocautery.

PLACEMENT

Placement of the graft can be done either Endonasally or using

an open approach.

If an endonasal approach is used, it is important for the surgeon

to carry the marginal incision almost to the medial crural

footplate and then to dissect the lower lateral cartilage free along

its length.

This allows direct placement of the strut, which will not bend

significantly, and minimizes the risk of fracturing the implant.

The marginal and transfixion sutures are closed with 4-0

chromic gut.

The nose is then taped and cast in standard fashion. A stabilizing

suture can be placed in a septal-columellar fashion. Because

driving a needle through the implant risks fracture, place the

suture just posterior to the implant in the membranous septum.

Recent AdvanceMASTOID BONE A NEW GRAFT MATERIAL IN

RHINOPLASTY

The mastoid bone graft provides adequate autologous bone

in most cases of primary or revision rhinoplasty.

The donor site carries low morbidity and a well

camouflaged scar.

It is easily accessible especially for the otolaryngologist

who is accustomed to operating on the mastoid bone

Referemces :Scott Brown 7th Edition

Barone CM, Jimenez DF and Goodrich JT (2008).

Exorbitism. In: Goodrich JT (ed.), Neurosurgical

Operative Atlas. Paediatric Neurosurgery, 2nd edn. New York: Thieme, pp. 76-82.

Chait LA, Becker H and Cort A (1980). The versatile costal osteochondral graft in nasal reconstruction.

Br J Plast Surg, 33(2): 179-184.

David DJ and Moore MH (1989). Cantilever nasal bone grafting with miniscrew fixation. Plast Reconstr Surg, 83(4): 728-732.

Farina R and Villano JB (1971). Follow-up of bone grafts to the nose. Plast Reconstr Surg, 48(3):251-255.

Gewalli F, Berlanga F, Ortiz-Monasterio F and Holmström H (2008). Nasomaxillary reconstruction in Binder Syndrome: bone versus cartilage grafts. A long-term intercenter comparison between Sweden and Mexico. J Craniofac Surg, 19(5): 1225-1236.

External Rhinoplasty The elephant trunk incision, the trans columellar incision, The

decortication technique, the external approach and open or

external rhinoplasty.

INDICATIONS

Congenital deformities, such as the cleft lip nose

Extensive revision surgery

Severe nasal trauma

Elaborate reduction and augmentation procedures

Marked tip deformities

The need for extra tip rotation

The correction of extreme overprojection

Situations where assessment of the exact pathology is difficult.

PRINCIPLES OF EXTERNAL RHINOPLASTY Conservation of the structural support of the nose by

exposing the pathology and allowing open access for

corrective surgical manoeuvres.

Correct incision placement and meticulous wound closure

are essential.

Lower and upper lateral cartilages together with the bony

dorsum can be exposed to the nasofrontal angle in their

undisturbed positions.

By dividing the upper laterals from the quadrilateral

cartilage, the whole of the septum is accessible from the

cephalic as well as the caudal aspect.

Other benefits include

Binocular vision

Use of both hands

Control of bleeding with diathermy

Precise placement and suturing of struts, Battens and shield

grafts

A very useful teaching tool.

It is important to appreciate that whilst the major tip support

mechanisms are respected in the external approach, the

disruption of the skin soft tissue envelope from the lower

lateral cartilages and the division of the medial intercrural

ligamentous fibrous tissue leads to loss of some of the minor

tip support mechanisms, and therefore some tip ptosis should

be anticipated in all cases.

SURGICAL TECHNIQUE

Incisions

The broken trans columellar incision is most commonly

used and variations include the step, gullwing and inverted

'V' configurations.

The mid-columella incision should be situated above the

level of the medial crural footplates to ensure adequate

support, thus preventing a depressed scar

The vertical columellar parts of the marginal incisions are

then placed 1.5-2 mm inside the vestibule and joined by

careful undermining with scissors of the columella skin.

SURGICAL TECHNIQUE

Dissection of the soft tissue envelope

This starts in the subperichondrial plane in the domal area.

It can be helpful to vertically incise the perichondrium at

the caudal end of the cartilaginous vault in the midline, after

which subperichondrial dissection can proceed from medial

to lateral and in a cephalic direction.

Dissection of the soft tissue of the bony pyramid in a

subperiosteal plane should start 2-3 mm parallel to and above

the caudal end of both nasal bones.

In the case of grafting procedures for augmentation, care

should be taken that the overlying soft tissue has sufficient

viability.

SURGICAL TECHNIQUE

Blanching of the skin over an augmentation graft is a

warning sign which should not be neglected.

A slight reduction of the graft size will prevent

possible skin necrosis.

A Meticulous closure of incision is done following

completion of surgery.