brazil-uk frontiers of engineering - big data in healthcare session

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Big Data in Healthcare Prof Roberto Marcondes Cesar Junior Dr Alejandra GonzalezBeltran

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Page 1: Brazil-UK Frontiers of Engineering - Big data in healthcare session

Big  Data  in  Healthcare  

Prof  Roberto  Marcondes  Cesar  Junior                     Dr  Alejandra  Gonzalez-­‐Beltran  

Page 2: Brazil-UK Frontiers of Engineering - Big data in healthcare session
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R Baraniuk, Science, 2011

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DNA  sequencing  technology    

enabling  clinical  applicaCons  with  the  goal  of  improving  medical  diagnosis  and  treatment  

(personalised  medicine)    

hIp://www.genome.gov/sequencingcosts/  

Mardis,  A  decade’s  perspecCve  on  DNA  sequencing  technology  Nature  2011  

Page 5: Brazil-UK Frontiers of Engineering - Big data in healthcare session

hIps://projects.ac/blog/five-­‐top-­‐reasons-­‐to-­‐protect-­‐your-­‐data-­‐and-­‐pracCse-­‐safe-­‐science/  

ScienCfic  data  and  the  effect  of  poor    research  data  management  

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hIp://www.nih.gov/news/health/oct2014/od-­‐09.htm  

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hIp://goo.gl/BJuzWE  

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hIp://metadatacenter.org  

hIp://goo.gl/BJuzWE  

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Data  volume  is  only  part  of  the  story…  in  the  conCnuum  of  translaConal  research  

From  bench  to  bedside…  

Page 14: Brazil-UK Frontiers of Engineering - Big data in healthcare session

Data  volume  is  only  part  of  the  story…  in  the  conCnuum  of  translaConal  research  

A  myriad  of  data  types  

Genes,  genomes  &  variaCon  

Literature  

Clinical  Gene,  protein  and  metabolite  

expression  

Protein  sequences,  families  &  moCfs  

Terminologies  

Molecular  Structures  Chemical  biology  

Systems  ReacCons,  interacCons,  pathways  

in  narraCve  form  semi-­‐structure  reports  electronic  health  records  

Imaging  

Survey  data  

Page 15: Brazil-UK Frontiers of Engineering - Big data in healthcare session

Data  volume  is  only  part  of  the  story…  in  the  conCnuum  of  translaConal  research  

A  myriad  of  data  types  

Genes,  genomes  &  variaCon  

Literature  

Clinical  Gene,  protein  and  metabolite  

expression  

Protein  sequences,  families  &  moCfs  

Terminologies  

Molecular  Structures  Chemical  biology  

Systems  ReacCons,  interacCons,  pathways  

in  narraCve  form  semi-­‐structure  reports  electronic  health  records  

Imaging  

Survey  data  

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escience.ime.usp.br

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Developments  in  genomics  and  molecular  diagnosCcs  in  UK  

100000  Genomes  Project  

Knowledge  management  infrastructure  for  translaConal  research  

Page 19: Brazil-UK Frontiers of Engineering - Big data in healthcare session

Privacy,  ConfidenCality  &  Ethical  issues    

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Acknowledgements