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B R O U G H T T O Y O U B Y L I N K A S I A P A R T N E R S

DECEMBER 2012 ISSUE NO. 12

LinkAsia ConnectCONTENTSSeasons GreetingsLinkAsia Partners wishes all a year of success and abundance in 2013

Distributor AppointmentBluewave Marine Ingredients appoints ACI as PerfectDigest™ distributor in Bangladesh

Product UpdateOpticell® Ruminant: A new tool for rumen productivity and gut function for the dairy and beef industry.

Application UpdateBiorigin and the NEMO project

EventsReviewEuroTier 201213-16 November 2012Hanover, Germany

15th AAAP Animal Science Congress26-30 November 2012Bangkok, ThailandPresentations from Animine

UpcomingVIV Asia 201313-15 March 2013BITEC, Bangkok Thailand

Pig Feed Quality Conference22-23 April 2013The Landmark Bangkok, ThailandComplimentary satellite symposium “New Tools for Sow and Piglet Productivity” on Sunday, 21 April 2013 sponsored by Agromed

As we move into 2013 I would like to think that much of the turmoil seen in the markets in 2012 is behind us. With the last minute resolution of the US “fiscal cliff” issue and more positive news out of Europe we hope the markets will reflect a more positive outlook in 2013. There are many positive signs with which to start the year of 2013!

From LinkAsia Partners’ perspective we look forward to another year of continued support of our clients and channel partners. Even more, we are

looking forward to supporting the launch of some new technologies, applications and solutions throughout Asia Pacific. Some of these solutions will be specifically targeted at the ever more important consumer awareness of food safety and animal welfare.

Adapted solutions that our clients products are focused on include:• Maximizing sow productivity in emerging open stall systems

supported by lignocellulose fibre.• Improving food safety, reducing environmental impact and piglet

productivity through the use of specialized and safe Zinc Oxide sources in Piglet diets.

• Implementation of programs to provide alternatives to antibiotics in animal feeds through the use of probiotics in feed and water.

• Providing 3rd generation feed hygiene technologies for managing salmonella challenges under current animal production systems.

• Prediction and management of SARA (sub acute rumen acidosis) and its impact on milk quality, fertility and productivity in ruminants.

• Specialized products for immune modulation.• Strategies to influence feed intake in piglets, sows and poultry using

peptides in feed and water.

Many of these technologies and applications will be on display during the upcoming VIV Asia in Bangkok in March 2013. At this show, the LinkAsia Partners booth will host the international partners from Agromed (Austria), Animine (France), Biorigin (Brazil), Bluewave (Peru & Ecuador) and Tecnozoo (Italy). We look forward to welcoming you to meet our partners and sharing some of the exciting developments in store for us in 2013.

Greetings from our CEO, David Saunders

Newsflash: Book into your schedule now the Pig Feed Quality Conference 2013 (22-23 April) organized by Asian Agribusiness Media where Agromed will hold a satellite symposium targeted at management tools for the sow and piglet on Sunday, 21 April, from 3.00pm to 5.00pm. This event will bring international experts and research together to present sow management under new production systems and innovative piglet feed ingredient strategies for improvement in productivity and health. For more information and to register, visit www.asian-agribiz.com/pdf/pigfeedQC13.pdf.

David SaundersCEO, LinkAsia Partners

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Bluewave Marine Ingredients recently announced ACI as its distributor of PerfectDigest™ products addressing the poultry, aquaculture and horticulture segments in Bangladesh. The appointment is aligned with Bluewave’s strategy to expand its geographical presence and penetrate the emerging markets in Asia.

Commenting on the partnership, M a r k R o t t m a n n , C O O o f Bluewave Marine Ingredients said, “ACI is at the forefront of t h e l i v e s t o c k f e e d a n d agriculture market in Bangladesh making them the ideal partner f o r d i s t r i b u t i o n o f PerfectDigest™. With ACI’s established distribution network and expertise, we are set to reach out to the emerging market in Bangladesh.”

Mohammad Shaheen Shah, Bus iness Manager Animal Health of ACI said, “We are glad to add PerfectDigest™ to our

product por t fo l io . As a n u t r i t i o n a l s u p p l e m e n t , PerfectDigest™ is best suited for use in layers, broilers, b re e d e r s a n d a l s o o t h e r livestock applications. With its quick results in enhancing FCR and stimulating feed intake, we are confident the product will be a success in Bangladesh. In a d d i t i o n , t h e i m p o r t a n t h o r t i c u l t u r a l m a r k e t i s demanding organic sources of fertilizer which is well supported by the Bluewave product line.”

“This partnership will kickstart t h e d i s t r i b u t i o n o f P e r f e c t D i g e s t ™ t o t h e Bangladesh poultry market via ACI’s broad and respected distribution network,” said David Saunders, CEO of LinkAsia Partners. “Considering the interest and enquiries we have been seeing from the market, PerfectDigest™ is the perfect match for customers looking for an effective growth promoter to boost productivity in livestock and agricultural operations.”

Distributor Appointment:Bluewave Marine Ingredients appoints ACI as PerfectDigest distributor in Bangladesh

About ACI Limited:Since its inception, Advanced Chemical Industries (ACI) Limited has flourished as the leading conglomerates in Bangladesh. It has diversified into four major business units - Pharmaceuticals, Consumer Brands & Commodity Products, Agribusiness and Retail Chain.

ACI Agribusiness is the leading integrator in Agriculture, Livestock and Fisheries in Bangladesh. These businesses have subunits like Crop Protection, Seed, Fertilizer, Agrimachineries, and Animal Health. ACI Agribusiness has strong partnership with national and international R&D companies, universities and research institutions. With a large, knowledgeable and highly skilled field force, ACI is able to provide training and technical advice to the farmers and significantly contribute to national food security.Visit www.aci-bd.com for more information.

Mohammad Shaheen ShahBusiness Manager Animal HealthACI Limited

Mark RottmannCOO, Bluewave Marine Ingredients

1-litre packaging for localized needs

Keen to market PerfectDigest™ in your region? Email info@linkasiapartners.com for more information

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Product Spotlight:Opticell® Ruminant: An All-Natural Solution for S.A.R.A.Opticell® Ruminant is a natural lignocellulose product designed for high performing ruminants including dairy cows, goats and beef cattle.

Starch-rich ruminant diets, inadequate mixing or other m a n a g e m e n t i s s u e s c a n dramatically lower  rumen pH with immediate negative effects on milk quality, consistency and volume as well milk fat levels. In the longer term, it may lead to

l a m e n e s s a n d l o s s o f fertility.  This effect is known as SARA ( sub-acu te rumina l acidosis). Currently, the industry practice is to use sodium bicarb to manage the rumen pH with negative consequences in feed intake or sodium elimination, in particular in heat stress periods. The unique ingredients contained in OptiCell® Ruminant naturally influence the degradation of

carbohydrates in the rumen thereby preventing rapid drop in  r u m e n p H . A s O p t i C e l l ® Ruminant is a natural product, there is no negative impact on mi lk or meat qua l i ty and consistency.

The unique mode of action of OptiCell® Ruminant makes this a safe, cost effective and proven tool to protect ruminants from SARA and its resultant economic losses.

Opticell® Ruminant for maximum and safe food production.

smaXtec: A New Tool for Real-time Rumen pH MonitoringWith pressure to increase milk yields, maintain milk consistency while managing changes in feedstuffs, a new tool was introduced at the recent Eurotier that provides real-time monitoring and reporting of the rumen pH. Sudden and even temporary drops in pH may not be detected easily without this new tool.

Now nutritionists and researchers have real-time internet based data to help them make better and faster decisions in terms of feeding management, feedstuff selection, inclusion levels and diet mixing. From smaXtec, this specially designed bolus transmits pH and temperature data to handheld or facility receivers where it is uploaded to the internet for offsite monitoring and alarms.

OptiCell® Ruminant was tested using the smaXtec technology. In SARA sensitive animals, a drop in rumen pH was observed during the control period (yellow area in Figure 1). With OptiCell® ruminant in the diet, the pH was effectively managed.

Figure 1

smaXtec pH bolus

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Application Update:Biorigin and the NEMO projectFor the last four years, Biorigin’s l ead ing β -g lucan p roduct MacroGard® has been the subject of a European Marie Curie ITN project known as NEMO. Researchers in the NEMO pro ject have been investigating the capabilities of b e t a - 1 , 3 / 1 , 6 - g l u c a n , MacroGard® to balance the immune system and i ts application in aquaculture. As the project draws to a close, what has this project meant for Biorigin and the aquaculture industry?

In 2007, Biorigin and 8 other E u ro p e a n p a r t n e r s , b o t h commercial and academic, were awarded a major research and development contract by the European Commission, under Marie Curie Initial Training Networks (ITN). This contract was for €3million, issued under the European Union’s Seventh Framework Programme (FP7) for a project known as ‘NEMO’.

NEMO, whose full title was ‘ T r a i n i n g n e t w o r k o n protective immune modulation in warm water fish by feeding

glucans’, was a 4 year project (2008-2012) to invest igate various aspects of β-glucan activity in fish. Across the partners, 16 researchers were employed. Table 1 summarises the partners and researchers of the NEMO project.

Each partner had its own roles wi th in the NEMO project . MacroGard®, the β-glucan product chosen for research due to its vast documentation and guarantee of bioactivity was provided by Biorigin. Technical information and support was co-ordinated by Managing Director Rolf Nordmo.

With a growing global demand fo r food p ro te in and the i m m e n s e g r o w t h o f t h e aquaculture industry in the last few decades, there has been fresh impetus for the research and development of substances beneficial for fish health and that could help control the frequent d i s e a s e o u t b r e a k s i n aquaculture. β-glucans were a prime candidate for further research.

Those involved in the NEMO project have been investigating MacroGard®’s role and effect on, for example, gene expression, innate phase proteins, cell apoptosis, gut physiology, membranal composition, the i n fl a m m a t o r y r e s p o n s e , b i n d i n g m e c h a n i s m s , neutrophil extracellular traps (NETs) and wound healing.

Fours years on, as the NEMO project draws to a close, there have been many interesting and exciting new discoveries with regards to MacroGard®.

NEMO has been a very valuable project for Biorigin. Not only has i t g e n e r a t e d f u r t h e r documentation for MacroGard®, supporting it as the most documented β-glucan for use in a n i m a l f e e d , b u t i t h a s highlighted new areas that could b e n e fi t f r o m β - g l u c a n application and kept Biorigin at the fo re f ront o f β -g lucan research.

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MacroGard® is a pure and natural product derived from baker’s yeast Saccharomyces cerevisiae.Processed by highly advanced and patented techniques, the product has undergone necessary purification giving a high yield of bio-active carbohydrates for inclusion in feeds and premixes. The product is free from material of animal source and GMO free.

Partner Location Origin PositionBiorigin Norway (Oslo) England MPhilTetra Germany (Melle) England MPhilBiomar Denmark (Brande) Sweden MPhilUniversity of Veterinary Medicine

Germany (Hannover)

PolandEngland

Post DocPhD

Danish Technical University

Denmark (Copenhagen)

ColumbiaPoland

PhDPhD

WageningenUniversity

Netherlands (Wageningen)

DenmarkDenmarkItaly

Post DocPhDPhD

Keele University UK (Keele)

GermanyFranceSpain

PhDPhDPost Doc

University of Plymouth

UK (Plymouth) Germany PhD

Institute of Ichthyobiology and Aquaculture

Poland (Golysz)

EnglandUkraine

PhDPhD

Table 1: Partners and researchers of the NEMO project

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Application Update:Biorigin and the NEMO projectThe NEMO project enabled research on a large scale over a relatively short period of time and the dissemination of recent findings across European feed and aquaculture industries.

Biorigin and the NEMO group have attended and participated in many events over the last four years. Key events have included the 15th conference of the European Association of Fish P a t h o l o g i s t s ( E A F P ) i n S e p t e m b e r 2 0 1 1 a n d a conference entitled ‘Prebiotics and probiotics in medicine, v e t e r i n a r y s c i e n c e s a n d

aquaculture: the future’ held at Keele University, September 2012.

Many papers have already been published by the NEMO group in highly acclaimed journals, and many more are expected in the near future.

In a broader spectrum, as the knowledge of β-glucans grows, so does the acceptance of their immunomodulating capabilities and their potential as a natural, s u s t a i n a b l e m e t h o d f o r maintaining healthy livestock and increasing productivity. This

could have significant impact in increasing turnover for related industries, enhancing cost-benefit for the end users (farmers) and contributing to meeting growing global food demands.

For more information, please c o n t a c t O l e F re t h e i m a t ole.fretheim@biorigin.net.

NEMO members: Geert Wiegertjes, Danilo Pietretti, Rolf Nordmo, Ilgiz Irnazarow, Anders Østergaard, Nicolas Pionnier, Sarah Harris, Mikolaj Adamek, Michael E. Nielsen, Anne Hjørngaard Larsen, Niels Hjermitslev, Dan Merrifield, Dieter Steinhagen, Graham Brogden, Patrick Frost, Natalia Vera Jiminez, Holger Kühlwein, Anna Sych, Inge R. Fink, Dominika Przybylska, Joanna Miest and Rebecca Heavyside. Missing NEMO members and close associates: Simon Davies, Gerd Grossheider, Alberto Falco, Martin Lingqvist, Patrycja Jurecka, Verena Schroers and Ole Fretheim.

Email us to learn more about MacroGard® in aqua feed and other applications. Write to us at info@linkasiapartners.com

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Event Review:EuroTier 2012 in Hanover, Germany EuroTier 2012 was held from 13-16 November in Hanover and the show has achieved a new record level with 2445 exhibitors and around 160,000 visitors from over 100 countries. Clients of LinkAsia, Agromed, Animine, Biorigin and Schaumann, were present at this top event for professional animal husbandry and showcased their leading products.

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Event Review:15th AAAP Animal Science Congress in Bangkok, ThailandThe 15th AAAP Animal Science Congress was held from 26 to 30 November in Bangkok, T h a i l a n d w i t h t h e t h e m e “Improving Smallholder and Industrial Livestock Production for Enhancing Food Security, E n v i r o n m e n t a n d H u m a n Welfare”.

T h i s C o n f e re n c e w a s a n opportunity for Animine to present results from three trials conducted in Asian countries. Tr ia ls were supervised by Chulalongkorn University in Thailand, Dankook University in

Korea and the Institute of Agricultural Sciences in Vietnam (see Figure 1).

H i Z o x ® , a s a s o u r c e o f potentiated zinc oxide, was tested at low inclusion rate in c o m p a r i s o n t o t h e pharmacological dosage of the regular ZnO in piglet diets. Trials d iffered by p ig le t age a t weaning, feeding program during the nursery phase, diet composition, levels and sources o f z i n c o x i d e , a n t i b i o t i c supplementation, and level of growth performance.

In the typical conditions found in the three countries, HiZox® fed piglets had the highest growth, resulting with increased weights at the end of the experimental phase (Figure 2).

To learn more about HiZox, p l e a s e w r i t e t o u s a t info@linkasiapartners.com.

Figure 1

Figure 2

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Event Upcoming:VIV Asia 2013 in Bangkok, ThailandVIV Asia 2013, the premier show in Asia, will be back in Bangkok from 13-15 March 2013 at the BITEC (Bangkok International Trade and Exhibition Centre). With almost 700 exhibitors from 40 countries, spread over 6 full halls, VIV Asia 2013 offers a unique platform where global players can network and boost business opportunities. With Aquatic Asia 2013 co-located prominently with VIV Asia, professionals active in the production of pig meat, poultry meat, eggs, fish and dairy all have numerous reasons to meet up in Bangkok this coming March. Visitors are expected, some 25,000 in total, from Asia, Australia/New Zealand, The Middle East, Africa and Japan.

Visit Hall 106, booth B020, where LinkAsia Partners and below clients will be present to showcase below interesting products:

From Austria, Agromed will be introducing its latest product offering, OptiCell® Ruminant, a natural lignocellulose product designed for high performing ruminants including dairy cows, goats and beef cattle.

Animine offers HiZox®, a unique and specialized source of zinc, manufactured under a patented process, which potentiates the known effects of zinc oxide in the post-weaning phase of the piglet.  Experience a demo of siMMin™, the newly launched software for establishing mineral balance in pig production which is now online.

Biorigin offers food ingredients, such as yeast extracts, inactive dry yeast, autolysed, and mineralized yeast; and industrial fermentation products, which include yeast extracts in amino-acids, minerals and vitamins, and nutrient complexes. Products include ActiveMOS, Biotide, Brewcell®, HiCell, MacroGard®, Selemax and more.

Bluewave Marine Ingredients offers specialized proteins, peptides and nucleotides derived from marine sources. Using patented membrane filtration technology, PerfectDigest™ products can be used across wide applications for human food, animal feed, pet food and fertilizer. 

Tecnozoo brings over 25 years of experience in the feed additive industry with a specific focus on nutrition, management, health and economics. From their controlled production systems, staff of specialized pharmacists, veterinarians, and nutritionists who are present at all steps in the value chain, Tecnozoo is now introducing their products to Asia Pacific. They will be focused on products targeted

for farm application for poultry, ruminants, swine and specialty applications.

Help us improve this enewsletter - we welcome your feedback and suggestions. Please send your comments to info@linkasiapartners.com.

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Pig Feed Quality Conference 2013 in Bangkok with Satellite Symposium sponsored by AgromedOrganized by Asian Agribusiness, Pig Feed Quality Conference will be held at The Landmark Bangkok Hotel from 22-23 April 2013, with two major themes, “Managing the increase in feed prices” and “Raising a healthy, fast-growing young pig”. Complimentary for conference delegates, don’t miss the symposium on Sunday, 21 April (1.00pm - 5.00pm) sponsored by Agromed, on “New tools for sow and piglet productivity”. This event will bring some international experts and research together to present sow management under new production systems as well as innovative piglet feed ingredient strategies for improvement in productivity and health.

Register early for Pig Feed Quality Conference and book your complimentary seat in this symposium. Check out www.asian-agribiz.com/pdf/pigfeedQC13.pdf for registration and more details.