Our Vision for the Future of the Common NMR Software Landscape

We envision two different software suites:�� One suite focusses on the spectrometer - including intelligent

and automatic data acquisition and processing.�� The other suite focusses on workflows and downstream data

analysis.

Both suites will work closely together and enable seamless information transfer.

Both suites will benefit from Mestre’s and Bruker’s know-how and IP:�� The suites will have access to a common library of algorithms.�� Both companies collaborate on strategic developments that

feed into this common library.

Overarching will be our cloud-based lab informatics solution.

Bruker and Mestrelab Research A Strong Strategic Alliance for the Benefit of NMR

Fig. 1: Smooth workflow for fragment based drug discovery (FBDD).

Fig. 2: A “one stop shop” for NMR analysis in biologics.

Common Development: Solutions for Fragment Based Drug DiscoveryA smooth workflow for fragment based drug discovery (FBDD): from assisted NMR experiment set-up and automated data acquisition to an easy-to-use manual interface for spectra analysis, as well as sophisticated automatic interpretation and binding hit detection. Both packages work seamlessly together and thus provide – in combination – the first complete solution for the entire system of NMR-based FBDD.

Common Development: Analysis of Higher Order Structure in BiologicsThe BiologicsHOS application is a tool for NMR researchers to analyze protein higher order structure (HOS) differences by 2D HSQC in order to evaluate this information as a QC criterion for Biologics – e.g. in the field of biologics productions. The application serves as a “one stop shop” for all the NMR analysis needs in this area.

Cloud basedlab informatics

Intelligentacquisition

andprocessing

Intelligentdownstreamdata analysis

Common library of algorithms