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SyllabuS

Yashwantrao Chavan Maharashtra

Open UniversityDnyangangotri, Near Gangapur Dam,

Nashik 422 222, IndiaPhone: 0253-2231714, 2231715, 2231473

Fax: 2231716Email: [email protected]

Website: http://www.ycmou.com/

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Bio-Technology Programme Curriculum Page 1 of 11

Contents1 Charts and Tables ............................................................................................................. 3

1.1 Bio-Technology Programme Structure Charts ............................................................... 3 1.2 Bio-Technology Programmes Details ............................................................................ 4 1.3 Biotechnology Course Details ...................................................................................... 4 1.4 Course Distribution Chart ............................................................................................ 5

2 Syllabus ............................................................................................................................ 6 2.1 Semester 08 ................................................................................................................ 6

2006, YCMOU. All Rights Reserved.Price: Indian Rs 200/- or US$ 50/- only. Free Download of Internet Version.Last Update: Saturday, June 27, 2009Printed By: Publisher: Registrar, YCMOU, Nashik 422 222, India.


1 Charts and Tables

1.1 Bio-Technology Programme Structure Charts1.1.1 For Odd Numbered Semesters

Mandatory CS Month September October November December January

Odd Numbered Semester

Course 14 CP, Theory

Course


Course


Course


Course

Course 54 CP, Practical or

Project-Work Course

01 SBT011:Basic Biology

SBT012:Communication

Skills

SBT013:Mathematics

SBT014:Environmental

Science

SBT015:Lab Course

03

SBT031:Basic

Biochemistry

SBT032:General

Microbiology-I

SBT033:Physiology

SBT034:Metabolism

SBT035:Lab Course

05

SBT051:Microbial

BiotechnologySBT052:

Immunology-I

SBT053:Genetic

Engineering-I

SBT054:Entrepreneurship

Development

SBT055:Lab Course

07SBT071:

Biochemistry SBT072:Enzymology

SBT073:Biophysical

Techniques-II

SBT074:Biostatistics

SBT075:Lab Course

09SBT091:

Immunology-IISBT092:Molecular Biology-II

SBT093:Genetic

Engineering-II

SBT094:Intellectual

Property Rights and Biosafety

SBT095:Lab Course

1.1.2 For Even Numbered SemestersMandatory CS Month March April May June July

Even Numbered Semester


Course


Course


Course


Course

Course 54 CP, Practical or

Project-Work Course

02SBT021:

Basic Statistics SBT022:Basic Chemistry

SBT023:Applied Physics

SBT024:Programming

Concepts

SBT025:Lab Course

04SBT041:

Cell Biology-I SBT042:Basic Biosciences

SBT043:Biophysical

Techniques-I

SBT044:Molecular Biology-I

SBT045:Lab Course

06

SBT061:Agricultural

Biotechnology

SBT062:Medical

Biotechnology

SBT063:Plant and Animal

Cell Culture

SBT064:Environmental Biotechnology

SBT065:Lab Course

08SBT081:General

Microbiology-II

SBT082:Cell Biology-II

SBT083:Genetics

SBT084:Bioinformatics

SBT085:Lab Course

10

SBT101:Plant Transgenics

and Tissue Culture

SBT102:Applications of Biotechnology

SBT103:Pharmaceutical Biotechnology

SBT104:Research

Methodology

SBT105:Project


1.2 Bio-Technology Programmes DetailsSN Programme For certification, student must confirm to

specified certification eligibility criteria and following courses specified for the respective programme must be successfully completed

Post-Graduate Degree Programme

1 M.Sc. (Bio-Technology) All 20 courses at semester 07 to 10

Graduate Degree Programme

1 B.Sc. (Bio-Technology) All 30 courses at semester 01 to 06

1.3 Biotechnology Course DetailsCP: Credit PointsCST: Counseling Session TimeSST: Self-Study TimeCat: Course Category from the below:

BS: Basic Science (Sem 01-02) DB: Discipline Basic (Sem 03-04) DC: Discipline Core (Sem 05-06) SC: Specialization Courses (Sem 0710)

Type: Course Type from the below: TH: Theory PR: Practical SP: Seminar or Project-Work

SN Semester Course

Code Name CP CST SST Marks Cat Type

1

1SBT011 Basic Biology 4 40 120 100 BS TH

2 SBT012 Communication Skill 4 40 120 100 BS TH

3 SBT013 Mathematics 4 40 120 100 BS TH

4 SBT014 Environmental Science 4 40 120 100 BS TH

5 SBT015 Lab Course 4 80 120 100 BS PR

6

2SBT021 Basic Statistics 4 40 120 100 BS TH

7 SBT022 Basic Chemistry 4 40 120 100 BS TH

8 SBT023 Applied Physics 4 40 120 100 BS TH

9 SBT024 Programming Concepts 4 40 120 100 BS TH

10 SBT025 Lab Course 4 80 120 100 BS PR

11

3SBT031 Basic Biochemistry 4 40 120 100 DB TH

12 SBT032 General Microbiology-I 4 40 120 100 DB TH

13 SBT033 Physiology 4 40 120 100 DB TH

14 SBT034 Metabolism 4 40 120 100 DB TH

15 SBT035 Lab Course 4 80 120 100 DB PR

16

4SBT041 Cell Biology-I 4 40 120 100 DB TH

17 SBT042 Basic Biosciences 4 40 120 100 DB TH

18 SBT043 Biophysical Techniques-I 4 40 120 100 DB TH

19 SBT044 Molecular Biology-I 4 40 120 100 DB TH

20 SBT045 Lab Course 4 80 120 100 DB PR

21

5SBT051 Microbial Biotechnology 4 40 120 100 DC TH

22 SBT052 Immunology-I 4 40 120 100 DC TH

23 SBT053 Genetic Engineering-I 4 40 120 100 DC TH

24 SBT054 Entrepreneurship Development 4 40 120 100 DC TH

25 SBT055 Lab Course 4 80 120 100 DC PR


SN Semester Course

Code Name CP CST SST Marks Cat Type

26

6SBT061 Agricultural Biotechnology 4 40 120 100 DC TH

27 SBT062 Medical Biotechnology 4 40 120 100 DC TH

28 SBT063 Plant and Animal Cell Culture 4 40 120 100 DC TH

29 SBT064 Environmental Biotechnology 4 40 120 100 DC TH

30 SBT065 Lab Course 4 80 120 100 DC PR

26

7SBT071 Biochemistry 4 40 120 100 SC TH

27 SBT072 Enzymology 4 40 120 100 SC TH

28 SBT073 Biophysical Techniques-II 4 40 120 100 SC TH

29 SBT074 Biostatistics 4 40 120 100 SC TH

30 SBT075 Lab Course 4 80 120 100 SC PR

26

8SBT081 General Microbiology-II 4 40 120 100 SC TH

27 SBT082 Cell Biology-II 4 40 120 100 SC TH

28 SBT083 Genetics 4 40 120 100 SC TH

29 SBT084 Bioinformatics 4 40 120 100 SC TH


26

9

SBT091 Immunology-II 4 40 120 100 SC TH

27 SBT092 Molecular Biology-II 4 40 120 100 SC TH

28 SBT093 Genetic Engineering-II 4 40 120 100 SC TH

29 SBT094 Intellectual Property Rights and Biosafety

4 40 120 100 SC TH


26

10

SBT101 Plant Transgenics and Tissue Culture

4 40 120 100 SC TH

27 SBT102 Applications of Biotechnology 4 40 120 100 SC TH

28 SBT103 Pharmaceutical Biotechnology 4 40 120 100 SC TH

29 SBT104 Research Methodology 4 40 120 100 SC SP

30 SBT105 Project 4 80 120 100 SC SP

1.4 Course Distribution Chart

1.4.1 As per Course CategorySN Course Category No of

CoursesCredit Points

% of Credit Points

Counseling Hours

% of Counseling

Hours

1 BS: Basic Science 10 40 20% 480 20%

2 DB: Discipline Basic 10 40 20% 480 20%

3 DC: Discipline Core 10 40 20% 480 20%

4 SC: Specialization Courses 20 80 40% 960 40%

5 Total 50 200 100% 2400 100%

1.4.2 As per Course TypeSN Course Type No of

CoursesCredit Points

% of Credit Points

Counseling Hours

% of Counseling

Hours

1 TH: Theoretical 40 160 80% 1600 67%

2 SB: Skill Based (PR and PW) 10 40 20% 800 33%

3 Total 50 200 100% 2400 100%


2 Syllabus

2.1 Semester 08

2.1.1 SBT081Code Course Name Prog Sem CP CST SST Marks Type Cat

SBT081 General Microbiology-II BT 8 4 40 120 100 TH SC

Course Prerequisites: Microbiology in B.Sc.

Course Objectives: After successful completion of this course, student should be able to

explain various microbes

Remarks:

UN Name of Unit CP CST Evaluation Pattern

1 Prokaryotes and Eukaryotes 1 10 1 SAQ & 1 LAQ (in End Exam) and 5 MCQs

(in Self-Test) will be asked on these units.

2 Microbial Classification2 10 1 SAQ & 1 LAQ (in End Exam) and 5 MCQs


3 Viruses 3 10 1 SAQ & 1 LAQ (in End Exam) and 5 MCQs


4 Microbial Development and Photosynthesis 4 10

1 SAQ & 1 LAQ (in End Exam) and 5 MCQs (in Self-Test) will be asked on these units.

UN Detail Syllabus of the Unit

1 Prokaryotes and Eukaryotes: Bacterial morphology, purple and green bacteria, cyanobacteria, budding and appendaged bacteria, mycobacteria, rickettsias, archaebacteria. Algae : General characteristics, Fungal and slime moulds : General characterstics,

2 Microbial Classification: Phylogenetic classification ,Methods of classification i)Intuitive method ii) Numerical taxonomy iii)Based on base composition iv)Nucleic acid hybridization, Nucleic acid sequencing (out line only), Bergeys Manual of Systematic Bacteriology (outline only)

3 Viruses: Nature, symmetry, capsid structure, nucleic acid. Quantification of viruses. Life cycles: T4 and Lambda. Important viruses in biotechnology-M13, Lambda, retroviruses, adenoviruses, adeno associated viruses, and HIV. viroids and prions.

4 Microbial Development and Photosynthesis: Sporulation and morphogenesis, multicellular organizations of selected microbes, dormancy, oxygenic and anoxygenic photosynthesis, bioluminescence

Book Code Title, Author, ISBN of Original Edition

Details of Chapters and Sections Included in Syllabus

EditionYear

Publisher, Price, Order It Here

Text Books

SBT081-T1 Microbiology Pelczar chan, krige

Included: Excluded:

Tata Mcgrawhill pub

Reference Books

SBT081-R1 Fundamentals of microbiologyAlcanaoe

Jogmamdar pub



SBT082 Cell Biology-II BT 8 4 40 120 100 TH SC

Course Prerequisites: Cell Biology in B.Sc.


know about the processes occurring in cell

Remarks:


1 Cytoskeleton1 10


2 Membrane Transport 2 10


3 Cell Signaling3 10


4 Cell Cycle and Cancer4 10



1 Cytoskeleton: The self assembly and dynamic structure of cytoskeletal filaments, regulation of cytoskeletal filaments, molecular motors, cytoskeleion and cell behavior.

2 Membrane Transport: Active and passive transport, mediated and non mediated transport. Carrier proteins Na+ driven pumps, Na+- K+ ATPase pump,Ca2+,H+ pumps, symport, antiport, uniport, group translocation, Ion channels and the electrical properties of membranes.

3 Cell Signaling: General principles of cell communication. Signaling through G- Protein linked cell-surface receptors. Signaling through enzyme linked cell surface receptors , secondary messenger , regulation of cell signaling in plants.

4 Cell Cycle and Cancer: An overview of the cell cycle, components of the cell cycle, control system, intracellular control of cell-cycle events. Programmed cell death ( Apoptosis ) ,Cancer as a micro evolutionary process. The causes of cancer, finding the cancer critical genes, the molecular basis of cancer-cell behavior, cancer treatment and prevention : present and future.



EditionYear


Text Books

SBT082-T1 Molecular and cell biologyGerald karp

Included: Excluded:

Wile-liss

Reference Books

SBT082-R1 Cell and molecular biologyDe Robertis and EMF De Robertis

Philadephia pub.



SBT083 Genetics BT 8 4 40 120 100 TH SC

Course Prerequisites: Genetics in B.Sc.


explain concepts in Genetics

Remarks:


1 Mendelian Genetics1 10


2 Population Genetics2 10


3 Genetic Diseases3 10


4 Complexities of Genetics4 10



1 Mendelian Genetics: Mendelian principles, the concept of the gene, Dominance, multiple allelic systems, gene interaction, linkage, diploid, Ploidy, various types of mutations, Environmental mutagens

2 Population Genetics: Hardy-Weinberg law, Inbreeding and heterosis plant improvement,

hybridization. Chromosome alteration and sister chromatid exchanges Lethals, Detection of

genotoxicity

3 Genetic Diseases: Autosomal Recessive Disorders, Autosomal dominant disorders, X-linked diseases, Genetic predisposition, Pedigree study.

4 Complexities of Genetics: Behavioral traits and Eugenics, Polygenic traits, Familial and Heritable traits, Measuring heritability. Twin studies, Behavioral studies. Detection of DNA damage at molecular level, Ames test.



EditionYear


Text Books

SBT083-T1 Principles of geneticstamarin

Included: Excluded:

Tata Mcgrawhills

Reference Books

SBT083-R1 Genetics strickberger

Johnwilley pub.



SBT084 Bioinformatics BT 8 4 40 120 100 TH SC

Course Prerequisites: Basic knowledge about computer

science and Biological science


use databases available on Internet

Remarks:


1 Softwares and Packages1 10 1 SAQ & 1 LAQ (in End Exam) and 5 MCQs


2 Database Management2 10 1 SAQ & 1 LAQ (in End Exam) and 5 MCQs


3 Computer Analysis of Genetic Sequences 3 10


4 Proteomics and Drug Designing4 10 1 SAQ & 1 LAQ (in End Exam) and 5 MCQs



1 Softwares and Packages : Use of standard operation Systems : MS DOS and Window.Use of

standard packages and softwares : Sigma plot, Origin, Antivirus ( Virus monitoring ) packages.

Concept of networking: Internet, internet concepts, web browsing, public domain resources in

biology.

2 Database Management: Brief idea of data types, data structures, searching, sorting, designing

a database, genomic, proteomic and metabolic pathways databases.

3 Computer Analysis of Genetic Sequences: general concepts of sequence analysis,

identification of functional sequences, homology brief idea of BLAST, ENTREZ and PuBMed.

4 Proteomics and Drug Designing: basic issues and concepts, protein sequences and alignment, protein structure prediction Bioinformatics tool in drug design.



EditionYear


Text Books

SBT084-T1 Bioinformatics a beginners guideJaenmichelle claverie

Included: Excluded:

Wiley-dreamtech India pvt ltd

Reference Books

SBT084-R1 Developing bioinformatics computer skillsCynthia gibas and per jambeck

O reilly



SBT085 Lab Course BT 8 4 80 120 100 PR SC

Course Prerequisites: Basic knowledge of practical


perform practical based on Microbiology and Bioinformatics

Special Note: Study Centers should conduct any 20 activities out of total 24 activities given in the list. Students are expected to perform all activities mentioned in each experiment and maintain the up-to-date journal and get certified from the lab instructor.


1Isolation of single colony on solid media : Streak plate and Spread plate method

2 Staining techniques : Simple staining, Gram staining, Acid fast staining, Endospore staining , and Viable count

3 Hanging drop method for motility

4Anaerobic cultivation method

5 Determination of antibiotic resistance of bacteria

6 Demonstration of oligodynamic action

7 Determination of phenol coefficient

8 Effect of salt, sugar and pH on microbial growth.

9 Different methods of homogenization of animal and plant tissues & subcellular fractionation

10 Preparation of temporary slides of mitosis from onion root tips.

11 Preparation of temporary slides of meiosis from Tradescantia buds.

12 Histology of animal tissues. (Permanent slides)

i) epidermal cells (skin)

ii) nerve cells

iii) connective tissue-blood, bone, cartilage, Muscular tissue- striated, non-striated, cardiac

muscles

13Histology of plant tissues

i) Preparation of temporary slides- monocot/ dicot- stem/root.

ii) Leaf- isobilateral, dorsiventral.

14Preparation of permanent slides-Polytene chromosomes.

15 Mono and dihybrid crosses in DrosophilaMendels laws of genetics

16 Genome analysis of polyploids

17 Karyotype analysis

18 Human pedigree analysis

19 To solve problems concerning quantitative traits

20 Computer aided visualization of amino acid sequence of protein and its 3D structure.

21 Computer aided visualization of amino acid sequence of protein and its 3D structure

22 Retrieving metabolic pathway using internet.

23 Homology searching using BLAST

24 Computer aided survey of scientific literature




EditionYear


Text Books

SBT085-T1 Practical MicrobiologyVinita Kale, Kishore Bhusari

Included: Excluded:

Himalaya Publishing House

Reference Books

SBT085-R1 BioinformaticsC.S.V. Murthy

Himalaya Publishing House


1 Charts and Tables1.1 Bio-Technology Programme Structure Charts1.1.1 For Odd Numbered Semesters1.1.2 For Even Numbered Semesters

1.2 Bio-Technology Programmes Details1.3 Biotechnology Course Details1.4 Course Distribution Chart1.4.1 As per Course Category1.4.2 As per Course Type

2 Syllabus2.1 Semester 082.1.1 SBT0812.1.2 SBT0822.1.3 SBT0832.1.4 SBT0842.1.5 SBT085

bt sem8

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