Welcome

Dear Tim,

as far as I know this is the first patient treated with CAVH in the world. We performed this treatment in Vicenza in 1984 and the patient survived. After that we published the first series of 4 newborns treated with CAVH (Kidney

International 1986) . You made a great deal of progress since then and even more with this meeting. Best Wishes Claudio Ronco

Time and Transition 1984-Ronco’s KI paper 1990-CAVH becomes more common 1993-CVVH with adapted machinery 1995-automated CVVH(D) machinery 1997-ultrafiltration controllers with automated

machinery 1998-Acute Dialysis Quality Initiative (ADQI.net) 1999-Thermic controls with automated

machinery

Time and Transition 2000-1st International Conference on Pediatric

Continuous Renal Replacement Therapy 2001-1st FDA approved Bicarbonate Based

Dialysate (Normocarb) 2001-ppCRRT Registry establishment (Stu

Goldstein) 2001-Goldstein data on FO and outcome 2002-Citrate anticoagulation 2002-PCRRT 2 2002-PEDCRRT list serve

Time and Transition Gambro releases Prismasate 2003-DiCarlo data on early intervention in

Bone Marrow Transplantation 2004-Foland data on FO and outcome 2004-Data emerging on Pharmacy Errors 2004-PCRRT 3 2005-KI paper from ppCRRT 2006 PCRRT-Zurich

DIALYSIS MODALITY

0

10

20

30

40

50

60

HD PD CRRT

Belsha et al., Pediatr Nephrol, 1995

Pat

ien

ts (

%)

Pediatric Choice of RRT

0

10

20

30

40

50

60

1992 1994 1996 1998 2000 2002

PD

HD

CRRT

# o

n R

RT

/yr

Year of RRT

Why has this become common? Work in vascular access Dedicated staff who is interested in these

children Patients continue to be sicker then

historically Automated machinery has made the care

easier Anticoagulation protocols have made it easier

CRRT: Who does it?

Outside of NA wide country variation of whom is responsible for this therapy

Within NA USA ~ 60% done by Nephrology but

often determined by manpower Adult Nephrologists = Adult Intensivists Pediatric Nephrologists < Pediatric Intensivists

Canada ~ 50% done by Nephrology

Who really does CRRT?

Nursing staff of the

Dialysis units- thank you Critical Care units- thank you Neonatal intensive Care units- thank

you

What is the purpose of this meeting?

To bring together those in the field who deal with any modality of MOSF with RRT who are willing to listen and learn, to talk and to exchange

There are no experts in this field!! “If you quit learning then it is time to go home”

(actually he said get the hell out before you hurt someone!)

Robert Vernier MD (U of Mn, retired)

Thank you To those of you who helped make this

meeting happen Faculty Carol Malone

Program and Meeting planner-USA Katrin Burow

Program and Meeting planner-Europe PCRRT Organizing committee PCRRT Foundation, Inc

Who are the faculty?

Oskar Baenziger, MD University Children’s Hospital, Zürich,

Switzerland

Klaus-Eugen Bonzel, MD University Children’s Hospital, Essen,

Germany

Who are the faculty?

Patrick D. Brophy, MD, FRCPC C.S. Mott Children’s Hospital at the

University of Michigan, Ann Arbor, Michigan, USA

Timothy E. Bunchman, MD DeVos Children’s Hospital, Grand Rapids,

Michigan, USA

Who are the faculty?

Ali Dodge-Khatami, MD, PhD University Children’s Hospital, Zürich,

Switzerland

Michel Fischbach, MD Hôpital de Hautepierre, Strasbourg, France

Who are the faculty?

Bernhard Frey, MD University Children’s Hospital, Zürich,

Switzerland

Andree V. Gardner DeVos Children’s Hospital, Grand Rapids,

Michigan, USA

Who are the faculty?

John J. Gardner, RN DeVos Children’s Hospital, Grand Rapids,

Michigan, USA

Peter Gessler, MD University Children’s Hospital, Zürich,

Switzerland

Who are the faculty?

Markus J. Kemper, MD University Children’s Hospital Eppendorf,

Hamburg, Germany

Ernst P. Leumann, MD University Children’s Hospital, Zürich,

Switzerland

Who are the faculty?

Marco Maggiorini, MD University Hospital, Zürich, Switzerland

Thomas J. Neuhaus, MD University Children’s Hospital, Zürich,

Switzerland

Who are the faculty?

Ekkehard Ring, MD Medical University Graz, Graz, Austria

Thanks to our Supporters-1

Arrow International Baxter Health Care Dialysis Solution Inc Edwards Life Sciences Freseuius Gambro Hospal Janssen-Cilag

Novo Nordisk Novartis Pfizer Roche Vicor Government of Zurich (city and county) Swiss parents association of children with

kidney disease

Thanks to our Supporters-2

Who are the Audience

27 abstracts were submitted from 12 separate countries

50% make up of Nursing 45% physician 5% pharmacist

A few requests

Ask questions.. we all learn

Interact with others outside your program during the breaks, lunch

Visit the booths learn what each machine, solution, and

access can do for your program

A few requests

Fill out your evaluation cards and hand them into the desk CMEs and CEUs are available for those

requesting

Finally

Have fun and open your mind This is a therapy that is still in

development. The applications of these therapies are without boundaries

If Carol Malone, Katrin Burow, Thomas Neuhaus, Oskar Baenziger or I can help you in any way, please do not hesitate to ask.

Quote that I live by

“the smartest one in the room is the child”