cancer cells grow and divide when they should not

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Cancer cells grow and divide when they should not • Mitosis – an asexual cell division, that occurs in somatic cells – “Soma” = body • Cell cycle – the “lifecycle” of the cell

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Cancer cells grow and divide when they should not. Mitosis – an asexual cell division, that occurs in somatic cells “Soma” = body Cell cycle – the “lifecycle” of the cell. The Cell cycle: Interphase. Interphase has three phases: G 1 : cell grows, organelles duplicate - PowerPoint PPT Presentation

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Page 1: Cancer cells grow and divide when they should not

Cancer cells grow and divide when they should not

• Mitosis – an asexual cell division, that occurs in somatic cells– “Soma” = body

• Cell cycle – the “lifecycle” of the cell

Page 2: Cancer cells grow and divide when they should not

The Cell cycle: Interphase

• Interphase has three phases:– G1: cell grows, organelles

duplicate– S: DNA is replicated– G2: cell makes proteins

needed to complete cell division

Page 3: Cancer cells grow and divide when they should not

DNA replication

• Produces exact copies of the cells chromosomes

• Nucleotides are added by an enzyme called DNA Polymerase

• semiconservative replication - each newly replicated DNA molecule contains a daughter and a parental DNA strand

Page 4: Cancer cells grow and divide when they should not

Following replication, the DNA sequence ACCGTA would be paired with a daughter DNA strand with the sequence:

A. ACCGTAB. TGGCATC. ATGCCAD. UGGCAT

A. B. C. D.

25% 25%25%25%

Page 5: Cancer cells grow and divide when they should not

• Chromosomes are uncondensed before cell division

• Duplicated chromosomes are called sister chromatids

• They are held together at the centromere

DNA replication duplicates chromosomes

Page 6: Cancer cells grow and divide when they should not

Page 7: Cancer cells grow and divide when they should not

• Mitosis produces genetically-identical daughter nuclei

• Four stages:– Prophase– Metaphase– Anaphase– Telophase

• Mitosis is followed by cytokinesis, which splits the two nuclei into two daughter cells

The Cell cycle: Mitosis

Page 8: Cancer cells grow and divide when they should not

Mitosis : Prophase and Metaphase

Page 9: Cancer cells grow and divide when they should not

Mitosis : Anaphase and Telophase

Page 10: Cancer cells grow and divide when they should not

When cells grow and divide out of control, they cause a group of diseases called cancer

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