cancer risk from exposure to uranium among the navajo€¦ · • united states geological survey,...
TRANSCRIPT
![Page 1: Cancer Risk from Exposure to Uranium among the Navajo€¦ · • United States Geological Survey, Flagstaff (Dr. Margaret Hiza) ... Dr. Ruby (“Rez Vet”) examination Summer students](https://reader033.vdocuments.net/reader033/viewer/2022052003/60166aeea8762b422e277e03/html5/thumbnails/1.jpg)
Jani C. Ingram, Ph.D., Department of Chemistry & Biochemistry, Northern Arizona University, Flagstaff, AZ
Partnership for Native American
Cancer Prevention
Cancer Risk from Exposure to Uranium among the Navajo
![Page 2: Cancer Risk from Exposure to Uranium among the Navajo€¦ · • United States Geological Survey, Flagstaff (Dr. Margaret Hiza) ... Dr. Ruby (“Rez Vet”) examination Summer students](https://reader033.vdocuments.net/reader033/viewer/2022052003/60166aeea8762b422e277e03/html5/thumbnails/2.jpg)
• To determine environmental uranium information specific to the Navajo Lands.
• To bridge the gap between environmental science and cancer research by providing our results to our collaborators including Tribal leaders and community members.
• To provide a research experience for Native American students that is both scientifically challenging and of interest to them and their communities.
Project Goals
![Page 3: Cancer Risk from Exposure to Uranium among the Navajo€¦ · • United States Geological Survey, Flagstaff (Dr. Margaret Hiza) ... Dr. Ruby (“Rez Vet”) examination Summer students](https://reader033.vdocuments.net/reader033/viewer/2022052003/60166aeea8762b422e277e03/html5/thumbnails/3.jpg)
Project Overview
![Page 4: Cancer Risk from Exposure to Uranium among the Navajo€¦ · • United States Geological Survey, Flagstaff (Dr. Margaret Hiza) ... Dr. Ruby (“Rez Vet”) examination Summer students](https://reader033.vdocuments.net/reader033/viewer/2022052003/60166aeea8762b422e277e03/html5/thumbnails/4.jpg)
Key Issues: Collaborating with Native Nations • Native Nations are sovereign. • Every Native Nation has its own
government and governmental processes. • Cultural differences between majority
populations and Native populations as well as between different Tribes are important.
• Face to face meetings important, particularly through visits to the Reservation
• Patience and respect are key.
![Page 5: Cancer Risk from Exposure to Uranium among the Navajo€¦ · • United States Geological Survey, Flagstaff (Dr. Margaret Hiza) ... Dr. Ruby (“Rez Vet”) examination Summer students](https://reader033.vdocuments.net/reader033/viewer/2022052003/60166aeea8762b422e277e03/html5/thumbnails/5.jpg)
Navajo Nation
![Page 6: Cancer Risk from Exposure to Uranium among the Navajo€¦ · • United States Geological Survey, Flagstaff (Dr. Margaret Hiza) ... Dr. Ruby (“Rez Vet”) examination Summer students](https://reader033.vdocuments.net/reader033/viewer/2022052003/60166aeea8762b422e277e03/html5/thumbnails/6.jpg)
Navajo Nation
Slide compliments of Tommy Rock
![Page 7: Cancer Risk from Exposure to Uranium among the Navajo€¦ · • United States Geological Survey, Flagstaff (Dr. Margaret Hiza) ... Dr. Ruby (“Rez Vet”) examination Summer students](https://reader033.vdocuments.net/reader033/viewer/2022052003/60166aeea8762b422e277e03/html5/thumbnails/7.jpg)
Study Sites – Southwestern Navajo
Cameron
Blackfalls
Leupp
![Page 8: Cancer Risk from Exposure to Uranium among the Navajo€¦ · • United States Geological Survey, Flagstaff (Dr. Margaret Hiza) ... Dr. Ruby (“Rez Vet”) examination Summer students](https://reader033.vdocuments.net/reader033/viewer/2022052003/60166aeea8762b422e277e03/html5/thumbnails/8.jpg)
Open pit mine Home in Cameron
Blackfalls wells
Study Site Pictures
![Page 9: Cancer Risk from Exposure to Uranium among the Navajo€¦ · • United States Geological Survey, Flagstaff (Dr. Margaret Hiza) ... Dr. Ruby (“Rez Vet”) examination Summer students](https://reader033.vdocuments.net/reader033/viewer/2022052003/60166aeea8762b422e277e03/html5/thumbnails/9.jpg)
Sampling on the Reservation
![Page 10: Cancer Risk from Exposure to Uranium among the Navajo€¦ · • United States Geological Survey, Flagstaff (Dr. Margaret Hiza) ... Dr. Ruby (“Rez Vet”) examination Summer students](https://reader033.vdocuments.net/reader033/viewer/2022052003/60166aeea8762b422e277e03/html5/thumbnails/10.jpg)
• Students and their families • Specific Navajo communities and their
leaders • Navajo EPA (Federal government) and
Navajo Natural Resources (Tribal government)
• Navajo Institutional Review Board. • Other researchers working on similar
projects on Navajo Lands • Scientific collaborators
Collaborators
![Page 11: Cancer Risk from Exposure to Uranium among the Navajo€¦ · • United States Geological Survey, Flagstaff (Dr. Margaret Hiza) ... Dr. Ruby (“Rez Vet”) examination Summer students](https://reader033.vdocuments.net/reader033/viewer/2022052003/60166aeea8762b422e277e03/html5/thumbnails/11.jpg)
Student Researchers
![Page 12: Cancer Risk from Exposure to Uranium among the Navajo€¦ · • United States Geological Survey, Flagstaff (Dr. Margaret Hiza) ... Dr. Ruby (“Rez Vet”) examination Summer students](https://reader033.vdocuments.net/reader033/viewer/2022052003/60166aeea8762b422e277e03/html5/thumbnails/12.jpg)
Community Collaborators:
Cameron
Leupp Blackfalls
![Page 13: Cancer Risk from Exposure to Uranium among the Navajo€¦ · • United States Geological Survey, Flagstaff (Dr. Margaret Hiza) ... Dr. Ruby (“Rez Vet”) examination Summer students](https://reader033.vdocuments.net/reader033/viewer/2022052003/60166aeea8762b422e277e03/html5/thumbnails/13.jpg)
• Navajo Nation Institutional Human Health Review Board (Navajo IRB)
• Navajo Nation Deparment of Natural Resources
• Navajo Environmental Protection Agency
Governmental Collaborators:
![Page 14: Cancer Risk from Exposure to Uranium among the Navajo€¦ · • United States Geological Survey, Flagstaff (Dr. Margaret Hiza) ... Dr. Ruby (“Rez Vet”) examination Summer students](https://reader033.vdocuments.net/reader033/viewer/2022052003/60166aeea8762b422e277e03/html5/thumbnails/14.jpg)
Other Researchers working on Navajo:
NAU students training with UNM interviewers
• University of New Mexico Dineh Project (Dr. Johnnye Lewis)
• Institute for Tribal Envrionmental Professionals (Mansel Nelson – Environmental Education Outreach)
• United States Geological Survey, Flagstaff (Dr. Margaret Hiza)
• Southwest Research and Information Center (Chris Shuey) • Dine’ College (Perry Charley and Dr. Don Robinson)
![Page 15: Cancer Risk from Exposure to Uranium among the Navajo€¦ · • United States Geological Survey, Flagstaff (Dr. Margaret Hiza) ... Dr. Ruby (“Rez Vet”) examination Summer students](https://reader033.vdocuments.net/reader033/viewer/2022052003/60166aeea8762b422e277e03/html5/thumbnails/15.jpg)
Scientific Collaborators:
Margaret Briehl (Pathology) University of Arizona Cancer Center
Jamie Donatuto and Larry Campbell Swinomish Tribe
Nancy Johnson NAU Biology
Michael Ketterer Metro State U Environmental Analytical Chem
Paloma Beamer (Public Health) and Karletta Chief (Soil, Water, Environmental Science)
U of Arizona
Michael Lerma NAU
Political Science
![Page 16: Cancer Risk from Exposure to Uranium among the Navajo€¦ · • United States Geological Survey, Flagstaff (Dr. Margaret Hiza) ... Dr. Ruby (“Rez Vet”) examination Summer students](https://reader033.vdocuments.net/reader033/viewer/2022052003/60166aeea8762b422e277e03/html5/thumbnails/16.jpg)
Water Research
![Page 17: Cancer Risk from Exposure to Uranium among the Navajo€¦ · • United States Geological Survey, Flagstaff (Dr. Margaret Hiza) ... Dr. Ruby (“Rez Vet”) examination Summer students](https://reader033.vdocuments.net/reader033/viewer/2022052003/60166aeea8762b422e277e03/html5/thumbnails/17.jpg)
-20
0
20
40
60
80
100
120
140
160
Black Falls Ganado Bidahochi Kayenta/M.V. Tuba City
Con
cent
ratio
n (p
pb)
Uranium
![Page 18: Cancer Risk from Exposure to Uranium among the Navajo€¦ · • United States Geological Survey, Flagstaff (Dr. Margaret Hiza) ... Dr. Ruby (“Rez Vet”) examination Summer students](https://reader033.vdocuments.net/reader033/viewer/2022052003/60166aeea8762b422e277e03/html5/thumbnails/18.jpg)
Black Falls Ganado Bidahochi Kayenta/MV Tuba City
Arsenic
![Page 19: Cancer Risk from Exposure to Uranium among the Navajo€¦ · • United States Geological Survey, Flagstaff (Dr. Margaret Hiza) ... Dr. Ruby (“Rez Vet”) examination Summer students](https://reader033.vdocuments.net/reader033/viewer/2022052003/60166aeea8762b422e277e03/html5/thumbnails/19.jpg)
Traditional Food: Mutton Navajos and Sheep: • Mid 1600 sheep
introduced to Navajos.
• Navajos transitioned from hunter/gathers to farming and pastoralism.
• The amount of livestock symbolize the good life.
![Page 20: Cancer Risk from Exposure to Uranium among the Navajo€¦ · • United States Geological Survey, Flagstaff (Dr. Margaret Hiza) ... Dr. Ruby (“Rez Vet”) examination Summer students](https://reader033.vdocuments.net/reader033/viewer/2022052003/60166aeea8762b422e277e03/html5/thumbnails/20.jpg)
Research Goals • Quantifying levels of
uranium in sheep grazing on abandon uranium mines.
• Model for dietary metal exposure, utilizing indigenous Health Indicator (IHI) to assess health impact.
• Model uranium exposure.
![Page 21: Cancer Risk from Exposure to Uranium among the Navajo€¦ · • United States Geological Survey, Flagstaff (Dr. Margaret Hiza) ... Dr. Ruby (“Rez Vet”) examination Summer students](https://reader033.vdocuments.net/reader033/viewer/2022052003/60166aeea8762b422e277e03/html5/thumbnails/21.jpg)
Sample Collection 5 from Leupp – control (May 2013) 5 from Cameron – mine site (June 2013)
Dr. Ruby (“Rez Vet”) examination
Summer students from NAU, Dine’ College, Northland Pioneer College, Arizona Western College and community members working together
Ingram NAU Research Group
![Page 22: Cancer Risk from Exposure to Uranium among the Navajo€¦ · • United States Geological Survey, Flagstaff (Dr. Margaret Hiza) ... Dr. Ruby (“Rez Vet”) examination Summer students](https://reader033.vdocuments.net/reader033/viewer/2022052003/60166aeea8762b422e277e03/html5/thumbnails/22.jpg)
Sample Collection
• Kidney • Liver • Heart • Esophagus • Small
intestine • Large
Intestine • Stomach • Hoof
• Wool • Rib meat • Leg meat • Chest meat • Lungs • Fat • Leg bone
![Page 23: Cancer Risk from Exposure to Uranium among the Navajo€¦ · • United States Geological Survey, Flagstaff (Dr. Margaret Hiza) ... Dr. Ruby (“Rez Vet”) examination Summer students](https://reader033.vdocuments.net/reader033/viewer/2022052003/60166aeea8762b422e277e03/html5/thumbnails/23.jpg)
Results
• Similar results from control (Leupp) and mining (Cameron) areas • Next step to compare results to sheep raised off the Reservation • Sample collection December 12, 2015 in 100 miles from the Reservation
![Page 24: Cancer Risk from Exposure to Uranium among the Navajo€¦ · • United States Geological Survey, Flagstaff (Dr. Margaret Hiza) ... Dr. Ruby (“Rez Vet”) examination Summer students](https://reader033.vdocuments.net/reader033/viewer/2022052003/60166aeea8762b422e277e03/html5/thumbnails/24.jpg)
Future Work Fate and transport of uranium species under
environmental conditions that exist on Navajo Lands – uranium isotope ratio methods
Bioavailability of uranium Water exposure Soil exposure Plant exposure Livestock exposure – In Process Policy – T. Rock doctoral work
Continue to work with Navajo Nation to investigate specific chemistry/biological issues of interest to their communities
![Page 25: Cancer Risk from Exposure to Uranium among the Navajo€¦ · • United States Geological Survey, Flagstaff (Dr. Margaret Hiza) ... Dr. Ruby (“Rez Vet”) examination Summer students](https://reader033.vdocuments.net/reader033/viewer/2022052003/60166aeea8762b422e277e03/html5/thumbnails/25.jpg)
Acknowledgments Technical Assistance
• Dr. Michael Ketterer – ICP/MS (Metro State) • Ben Moan – environmental lab (NAU)
Collaborators • Cameron and Leupp Chapters • Blackfalls Community
Funding • Native American Cancer Prevention Program, National
Cancer Institute • National Institutes of Health – Training Grants at NAU • National Science Foundation – Undergrad Mentoring
in Environmental Biology and Research Experiences for Undergrads (summer)
• US EPA
![Page 26: Cancer Risk from Exposure to Uranium among the Navajo€¦ · • United States Geological Survey, Flagstaff (Dr. Margaret Hiza) ... Dr. Ruby (“Rez Vet”) examination Summer students](https://reader033.vdocuments.net/reader033/viewer/2022052003/60166aeea8762b422e277e03/html5/thumbnails/26.jpg)
Questions/Comments