© 2011/09 COSMED E & OE. Subject to alterations without prior notice. P/N.: C03226-02-93

Cardio Pulmonary Exercise Testing

A unique diagnostic solution for complete Cardio Pulmonary Assessment

► Maximal oxygen uptake (VO2max) and measured METs.

► Classification of Exercise Capacity & Anaerobic Threshold

► Nutritional Assessment and resting VO2 for Fick equation

► Full Spirometry (FVC, SVC, MVV, etc.)

► Multiple scores for Cardiovascular and Pulmonary Risk analysis

► Body composition & comprehensive Weight Management software

► Interfaces with conventional stress testing ECG

► Affordable, compact & easy to use

Fitmate MED measures maximal Oxygen Uptake, the gold standard for measuring exercise capacity and quantify aerobic fit-ness. Together with exercise electrocar-diography, Fitmate MED enables you to complete the cardio pulmonary stress test without the need of an expensive invest-ment, complicated procedures or special-ist expertise.

Patient rehabilitation is then managed with exercise prescription and weight management software according to es-tablished international guidelines.

Fitmate MED is the first diagnostic equip-ment designed to provide a complete pic-ture on cardio pulmonary function.

Clinical applications of VO2

► Actual measurement of Exercise Capacity and METs (not-estimated)

► Pre-operative evaluation for surgical risk

► Classification and prognosis of CHF (Congestive Heart Failure)

► Objective selection criteria and deci-sion tool for heart transplant

► Differentiation between cardiac and pulmonary limitation

► Determination of exercise train-ing intensity as part of cardiac rehabilitation

► Nutritional assessment during recov-ery from illness and chronic health management

► Obesity treatment and diabetes type II prevention

► Identification of energy requirements for respiratory disorders (COPD, sleep disorders, Cystic Fibrosis)

VO2max and real METs

► Choice between maximal and sub-maximal exercise protocols

► Real time display of pertinent respira-tory parameters

► Automatic and manual detection of anaerobic threshold

► Pre-defined (Bruce, cycle, ramp etc.) or user customizable exercise protocols

► Automatic exercise training heart rate zones based on oxygen uptake

► Warnings and quality control mes-sages (mask leaks, breathing pattern, etc.) are displayed during test

Resting Energy Expenditure

Fitmate MED measures oxygen consump-tion (VO2) at rest with high accuracy, comparable with conventional metabolic carts.

Spirometry

Complete spirometry testing (FVC, SVC, MVV, Pre/Post bronchial dilator response) is available with full compliance with ATS/ERS recommendations.

Comfortable silicone masks (5 sizes, both adult and paediatric) are available for exercise testing and one universal size disposable mask for resting measurements.

References

- 1) Validation of COSMED’s Fitmate™ in measuring exercise metabolism. [David C. Nieman, at al . Research in Sports Medicine, 15: 1–9, 2007.]

- 2) Validation of Fitmate in measuring REE [David C. Nieman, at al . Research in Sports Medicine, 14: 1–8, 2006.]

- 3) Validation of the Fitmate for predicting Maximal Oxygen Consumption [David Bassett, at al . JSCR, 25/9: 2573-2579, 2011.]

- 4) Comparison between Fitmate and Deltatrac in measuring REE in non-ventilated patients [Pierre Singer, at al . ESPEN 2010.]

Other Measurements

► Cardiovascular Risk Stratification (Duke Score, Framingham Index, European Heart Score, BODE Index)

► Individual weight management programs based on Energy Balance equation and diet plan based on daily caloric intake (USDA Database)

► Standard Measurements (BMI, WHR BP, etc.)

► Lifestyle monitoring (with optional physical activity monitor, Fitmate Lifecorder)

Exercise capacity and exercise Intensity for Cardiac Rehabilitation Training

Peak values

The graph shows VO2, HR, markers and typed BP measurements

Ventilatory limitation area for easy interpretation

Fitmate® Wellness Technology

Last Name: DEMO Age: 48 Membership #: 1First Name: PATIENT Height (cm): 175.00 Report Date: 15/05/2008Gender: Male Weight (Kg): 88.0 Personal Trainer:

FitMate version 1.5 (build 61) Page 1 of 1

Spirometry & SpO2

Volume/Time

PrePost

0 1 2 3 4 5 6 7 t012345678

V

Flow/Volume

0 2 4 6 V-8

-6

-4

-2

0

2

4

6

8

10

12

14F

DiagnosisModerately severe Obstruction

Quality CheckPEF reproducible,FVC reproducible,FEV1 reproducible

NameEVCIVCERVICIRVVERfVTBest FVCBest FEV1FVCFEV1FEV1/FVC%PEFFEV6FEV1/FEV6%MEF75%MEF50%MEF25%FEF25-75%Lung Age

DescriptionExpiratory Vital CapacityInspiratory Vital CapacityExpiratory Reserve VolumeInspiratory CapacityInspiratory Reserve VolumeVERfTidal VolumeBest Forced Vital CapacityBest Forced Exp Volume in 1 secForced Vital CapacityForced Exp Volume in 1 secFEV1 as % of FVCPeak Expiratory FlowForced Exp Volume in 6 secFEV1 as % of FEV6Max Exp Flow @ 25% FVCMax Exp Flow @ 50% FVCMax Exp Flow @ 75% FVCForced mid-expiratory flowLung Age

Units of meas.ll(btps)l(btps)lll/minb/minll(btps)l(btps)l(btps)l(btps)%l/secl(btps)%l/secl/secl/secl/secyears

Meas3.810.001.132.682.1812.826.100.4933.782.053.782.0554.35.283.7654.52.871.040.540.950

Post

3.662.053.662.0555.94.033.6556.12.671.220.481.010

% Pre

103100103100971311039710785112940

Pred.4.684.681.310.000.000.00.000.0004.493.644.493.6478.58.834.760.07.694.791.974.030

% Pred.8108600000845684566959790372127230

Fitmate® Wellness Technology

Last Name: DEMO Age: 47 Membership #: 1First Name: PATIENT Height (cm): 175,00 Report Date: 05/02/2008Gender: Male Weight (Kg): 88,0 Test Conducted by:

FitMate version 2.0 (build 20) Page 1 of 1

Cardio-respiratory Fitness

00.00 01.45 03.30 05.15 07.00 08.45 10.30 12.15 14.00 15.45 t0,0

5,0

10,0

15,0

20,0

25,0

30,0

35,0

40,0

45,0VO2/Kg (ml/Kg/min)

VO2max Pred

00.00 01.45 03.30 05.15 07.00 08.45 10.30 12.15 14.00 15.45 t0

20

40

60

80

100

120

140

160

180HR (bpm)

120/

80

140/

85

160/

87

140/

83

VO2/KgHR

00.00 01.45 03.30 05.15 07.00 08.45 10.30 12.15 14.00 15.45 t0,0

5,0

10,0

15,0

20,0

25,0

30,0

35,0VO2/HR (ml/bpm)

Rest

War

mup

Exer

c

Reco

very

00.00 01.45 03.30 05.15 07.00 08.45 10.30 12.15 14.00 15.45 t0,0

20,0

40,0

60,0

80,0

100,0

120,0

140,0VE (l/min)

MVV

Vent. limitation

VO2/HRVE

Gas ExchangeFunctional CapacityPeak VO2Measured Anaerobic ThresholdCardiovascularResting Heart RateMaximal Heart rateMaximal VO2/HREstimated peak Cardiac OutputEstimated peak Stroke VolumePulmonaryForced Exp Volume in 1 sMaximum Voluntary VentilationVEBreathing ReserveRfOtherLoadSpeedGrade

METSml/minml/Kg/min

bpmbpmml/bpml/minml

l(btps)l/minl/min%b/min

wattkmh%

Measured5,5

168011,5

68103

16,310,4101

2,0582,037,1

5533

1190,00,0

Normal> 6,9> 2112> 12,0

> 156> 13,6

> 2,94> 117,5

> 30< 50

Cardio-respiratory Fitness (ml/Kg/min)Impairment: None to mild

19,119,1D C B A

< 8,9 9,0 - 14,3 14,4 - 17,9 > 18,0

Anaerobic Threshold (ml/Kg/min)Impairment: Mild to moderate

11,511,5D C B A

< 7,9 8,0 - 10,9 11,0 - 13,9 > 14,0

Exercise Intensity for Cardiac Rehabilitation (HR)

HR (bpm)Load (watt)

Speed (kmh)%VO2R (---)

EE (Kcal/hour)

Very light75-800-00-1

10-24160

Light81-885-251-2

25-44230

Moderate88-9430-452-3

45-59---

Heavy94-10345-753-4

60-84---

Easy to replace, the O2 cell comes in a sealed bag. Lifespan is 12-18 months and it is indicated by the device.

Complete information and results of current open session or previously closed sessions. Ability to review serial test data. Full-color reports when printed from PC software.

Wide range of reports printable on PC (available in A4 or Letter size) Sample of a thermal printout (original size: 110mm wide)

© 2011/09 COSMED E & OE. Subject to alterations without prior notice. P/N.: C03226-02-93

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Distributed by:

COSMED srlHeadquarters

Via dei Piani di Monte Savello 37Pavona di Albano - Rome00041 ITALYPhone +39 06 931-5492Fax +39 06 931-4580

info@cosmed.com

USAConcord, CA

Phone +1 (925) 676-6002Fax +1 (925) 676-6005

Chicago, IL

Phone +1 (773) 645-8113Fax +1 (773) 645-8116

info@cosmedusa.com

CHINAGuangzhou

Phone +86 (20) 8332-4521Fax +86 (20) 8332-0683

china@cosmed.com

GERMANYSundern

Phone +49 (2933) 786-4387Fax +49 (2933) 786-4388

deutschland@cosmed.com

cosmed.com

COSMED srlHeadquarters

Via dei Piani di Monte Savello 37Pavona di Albano - Rome00041 ITALYPhone +39 06 931-5492Fax +39 06 931-4580

info@cosmed.com

Technical Specification

Tests w/Unit w/Software

Cardio Pulmonary Exercise TestingCardiorespiratory Fitness (VO2max, Anaerobic Threshold)

Automatic control of ergometers (bikes or treadmills)

HR interface w/ external ECG (TTL) m

Indirect Cardiac Output (Wassermann)

VO2/HR Training Zones (based on Anaerobic Threshold)

Exercise Intensity for Cardiac Rehabilitation

SpirometryForced and Slow Vital Capacity (FVC, SVC)

Maximal Voluntary Ventilation (MVV)

Bronchial Dilator test (Pre-Post)

Cardiovascular Risk AnalysisFramingham index

Duke score

Bode index

European Cardio Score

Nutritional AssessmentResting Energy Expenditure (REE, RMR)

Weight Management Program (Energy Balance)

Physical Activity Monitoring (integration with accelerometer) m

Diet Software w/ Weekly Meal Planner

Other measurementsBody Composition (skin-fold)

Standard Measurements (blood pressure, WHR, resting heart rate, BMI..)

Integrated Pulse Oximeter (SpO2) - Resting only m

Oxygen Consumption Measurements

Sensor Type GFC (Galvanic Fuel Cell)O2 Measurement range 0-25%Sampling Type Dynamic Mixing Chamber (international patent)Sampling Rate 30 sec / 60 secCalibration Automatic on room air (less than 20 seconds)Warm-up time 10 secondsAccuracy ± 2% (REE) ±0.02% (O2)O2 Sensor Lifespan 12-18 months

Flowmeter Ø 18mm Ø 28mm

Type Bidirectional digital turbine Bidirectional digital turbineVentilation range 0-50 l/min 0-300 l/minFlow resistance <0.7 cmH2O/l/s @ 3l/s <0.6 cmH2O/l/s @ 14l/sAccuracy Flow/Volume ±2% ±2%

Hardware

Dimensions & Weight 24 x 20 x 8 cm / 1.5kgDisplay (pixel) Color LCD 320 x 240Printer High speed thermal printer 12 cm (4,7 in)

Standard Packaging Includes

Fitmate MED unit, RMR flowmeter, VO2max flowmeter, RMR masks (10 pcs), silicone face mask, (M-size), head cap for silicone mask, AC/DC Adapter, USB cable, Fitmate PC Software (CD-Rom), antibacterial filters (5 pieces), mouthpieces (10 pieces) and paediatric mouthpiece adapter, body meter, oxygen sensor, HR belt and probe, carrying case.

Available languages

Firmware Italian, English, Spanish, German, French, Greek, Finnish, Dutch, Portuguese, Japanese, Chinese, Turkish, Russian, Polish, Slovenian

Software Italian, English, Spanish, German, French, Greek, Dutch, Portuguese, Chinese, Slovenian

Safety & Quality Standards

Equipment complies with MDD (93/42 EEC); EN 60601-1 (safety)/ EN 60601-1-2 (EMC) FDA 510(k) cleared.COSMED is an organisation whose quality management system is certified by CERMET according to UNI EN ISO 9001:2008 and UNI EN ISO 13485:2004.

*option WirelessRS-232 Port

USB Port TTL

HR COSMED belt and probe

COSMED ergometers

Fitmate Suite

Thermal printouts

Software printoutsUsers

COSMED Activity monitor

*

COSMED ECGs

*

*

Fitmate MED unit