case study near drowning - caccn study near drowning.pdf · perhilar, or diffuse pulmonary edema...
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Case Study:Case Study:
Near DrowningNear Drowning
Annabelle SmithAnnabelle Smith
RN, RN, BScNBScN
Case Study:
Near Drowning
Annabelle Smith
RN, BScN
Conclusion: Near DrowningConclusion: Near Drowning
Effects on surfactant key to treatment Effects on surfactant key to treatment requirements and survival requirements and survival
Initial hypothermia may be protective to Initial hypothermia may be protective to CVS & neurological systemsCVS & neurological systems
Water source importance debatable on Water source importance debatable on outcome resultsoutcome results
Amount of water & length in elements Amount of water & length in elements more importantmore important
Outline: Case StudyOutline: Case Study
••Definition Definition –– Near DrowningNear Drowning
••Presentation of our Presentation of our
••PathophysiologyPathophysiology
••Review of case studyReview of case study
••Conclusion Conclusion
Near DrowningNear Drowning
Aka Aka ““submersion injurysubmersion injury””
““survival, at least temporarily after survival, at least temporarily after
suffocation by submersion in a liquid suffocation by submersion in a liquid
mediummedium””
““wetwet”” near drowning near drowning -- aspiration of fluid aspiration of fluid
into lungsinto lungs
““drydry”” near drowning near drowning –– period of asphyxia period of asphyxia
secondary to secondary to laryngospasmlaryngospasm
Near Drowning SyndromeNear Drowning Syndrome
Depends on:Depends on:
––Duration of submersionDuration of submersion
––Amount of fluid aspiratedAmount of fluid aspirated
––Severity of hypoxiaSeverity of hypoxia
““One tough little ladyOne tough little lady…”…”
Aboriginal, 73 year old femaleAboriginal, 73 year old female
PMHX: DM2; HTN; HypothyroidismPMHX: DM2; HTN; Hypothyroidism
PSHX: PSHX: CholecystectomyCholecystectomy; R knee replacement; R knee replacementMedsMeds–– ASAASA
–– AmitriptylineAmitriptyline
–– NorvascNorvasc
–– LipitorLipitor
–– EnalaprilEnalapril
–– GlyburideGlyburide
–– MetforminMetformin
–– AvandiaAvandia
–– LL--thyroxinethyroxine
““One tough little ladyOne tough little lady…”…”
October 1 @ 1800October 1 @ 1800
Hunting moose in the Island Lake water Hunting moose in the Island Lake water system, Northern Manitobasystem, Northern Manitoba
Fell out of canoe while trying to assist her Fell out of canoe while trying to assist her groupgroup
Submerged for unknown amount of timeSubmerged for unknown amount of time
Son performed rescue breathingSon performed rescue breathing
Walked over an hour to STP nursing Walked over an hour to STP nursing stationstation
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@ STP nursing station@ STP nursing station
Initial vitals: Initial vitals:
–– Pulse 74Pulse 74
–– Resp. rate 30Resp. rate 30--4040
–– Temperature 30 degrees CTemperature 30 degrees C
–– O2 O2 satssats-- unable due to tempunable due to temp
–– NeuroNeuro: intact: intact
–– EKGEKG-- no acute changes; sinus rhythmno acute changes; sinus rhythm
–– C/S: crackles to bases; pink frothy sputumC/S: crackles to bases; pink frothy sputum
–– Projectile emesisProjectile emesis
–– RBS: 22.6RBS: 22.6
During During MedivacMedivac TransferTransfer
Frequent Frequent desaturationsdesaturations during flightduring flight
c/o:c/o:
–– GeneralizedGeneralized
pain pain
–– SOBSOB
–– Cough Cough
Arrives @ HSCArrives @ HSC
T 34 P 84 BP 96/59 RR 32 T 34 P 84 BP 96/59 RR 32
O2 O2 satssats with 15L 92%with 15L 92%
GCS 15/15GCS 15/15
Transferred to MICU Transferred to MICU
–– RR 53RR 53
–– BIPAPBIPAP
–– RespResp crackles at basescrackles at bases
PathophysiologyPathophysiology
Drowning begins with:Drowning begins with:
––Period of panicPeriod of panic
––Loss of normal breathing patternLoss of normal breathing pattern
––Breath holdingBreath holding
––Air hungerAir hunger
––Struggle by victim to stay above Struggle by victim to stay above waterwater
Aspiration > 11 ml/kg of body Aspiration > 11 ml/kg of body
weightweight……before blood volume before blood volume
changes occurchanges occur
Aspiration > 22 ml/kg of body Aspiration > 22 ml/kg of body
weight before electrolyte changes weight before electrolyte changes
occuroccur
Patient outcomes affected by:Patient outcomes affected by:
Initial treatment & time to Initial treatment & time to treatment centretreatment centre
Temperature of water Temperature of water
Length of submersion timeLength of submersion time
Presence of contaminantsPresence of contaminants
Freshwater / saltwater different Freshwater / saltwater different microorganismsmicroorganisms
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Patient outcomes affected by:Patient outcomes affected by:
Gram negative bacteria in drowning Gram negative bacteria in drowning
victims more virulentvictims more virulent
––Can cause immediate lethal sepsis Can cause immediate lethal sepsis
or infections months after incidentor infections months after incident
Strep or staph can also be presentStrep or staph can also be present
Fungus: incubation time 1Fungus: incubation time 1--4 weeks to 4 weeks to
6 months; often resistant 6 months; often resistant
Near Drowning: Pulmonary EffectsNear Drowning: Pulmonary Effects
Pulmonary insufficiency can develop Pulmonary insufficiency can develop insiduouslyinsiduously or rapidlyor rapidly
Leads to varying degrees of hypoxemiaLeads to varying degrees of hypoxemia
s/ss/s::
–– SOBSOB
–– RalesRales
–– WheezingWheezing
CXR / CT: vary from normal to localized, CXR / CT: vary from normal to localized, perhilarperhilar, or diffuse pulmonary edema, or diffuse pulmonary edema
Causes of Hypoxemia Causes of Hypoxemia
Reflex Reflex inspiratoryinspiratory efforteffort
Damage to surfactantDamage to surfactant
Decreased lung complianceDecreased lung compliance
Ventilation perfusion mismatchingVentilation perfusion mismatching
Intrapulmonary shunting Intrapulmonary shunting
……causes diffuse organ dysfunctioncauses diffuse organ dysfunction
Near Drowning: Pulmonary EffectsNear Drowning: Pulmonary Effects
Surface tension properties of surfactant Surface tension properties of surfactant
affectedaffected
Surfactant Surfactant ““washed outwashed out””
Water in alveoli Water in alveoli
–– Damages type 2 Damages type 2 pneumocytespneumocytes
–– Prevents production of new surfactant Prevents production of new surfactant
Loss of surfactant functionLoss of surfactant function
Near Drowning: Pulmonary Effects Near Drowning: Pulmonary Effects
Alveoli become unstableAlveoli become unstable
Complete/partial alveolar Complete/partial alveolar collapsecollapse……
Loss of ventilation resulting in Loss of ventilation resulting in intrapulmonary shunting & intrapulmonary shunting & hypoxemiahypoxemia
Near Drowning: Pulmonary Effects Near Drowning: Pulmonary Effects
Increased airway resistance secondary to:Increased airway resistance secondary to:–– Plugging of airway with debrisPlugging of airway with debris
–– Release of inflammatory mediators that result Release of inflammatory mediators that result on vasoconstrictionon vasoconstriction
–– May impair gas exchangeMay impair gas exchange
Combination Combination …… damage to damage to alveolar capillaries & alveolar capillaries & interstitiuminterstitium………… leads to ARDSleads to ARDS
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Near Drowning: Pulmonary EffectsNear Drowning: Pulmonary Effects
ARDS: develops within 48 hours in ARDS: develops within 48 hours in approximately 40% of approximately 40% of neardrowningneardrowningvictimsvictims–– Hallmarks of ARDS:Hallmarks of ARDS:
Decreased lung complianceDecreased lung compliance
Severe hypoxemiaSevere hypoxemia
Bilateral infiltrates on CXRBilateral infiltrates on CXR
Recovery occurs in 80% of casesRecovery occurs in 80% of cases
Only effective treatment is reversal of Only effective treatment is reversal of hypoxemia with mechanical ventilator hypoxemia with mechanical ventilator supportsupport
Neurologic EffectsNeurologic Effects
Hypoxemia & ischemia cause Hypoxemia & ischemia cause
neuronal damageneuronal damage
Can produce cerebral edema & Can produce cerebral edema &
elevation in ICPelevation in ICP
20% sustain neurologic damage 20% sustain neurologic damage ……
limits functional recoverylimits functional recovery
Cardiovascular effectsCardiovascular effects
Arrhythmias secondary to Arrhythmias secondary to
hypothermia & hypoxemiahypothermia & hypoxemia
Sinus Sinus bradycardiabradycardia & & atrialatrial fibrillation fibrillation
more common than ventricular more common than ventricular
fibrillation or fibrillation or asystoleasystole
Acid Acid –– Base & ElectrolytesBase & Electrolytes
Metabolic & respiratory acidosisMetabolic & respiratory acidosis
Significant electrolyte balances do not Significant electrolyte balances do not generally occur except those submerged generally occur except those submerged in unusual mediain unusual media
Dead Sea: extremely concentrated Dead Sea: extremely concentrated seawater leads to:seawater leads to:
–– HypernatremiaHypernatremia
–– HypermagnesemiaHypermagnesemia
–– hypercalcemiahypercalcemia
Renal EffectsRenal Effects
Failure rarely occursFailure rarely occurs
If it doesIf it does……
–– Usually due to acute tubular necrosisUsually due to acute tubular necrosis
Results from:Results from:
HypoxemiaHypoxemia
ShockShock
HemoglobinuriaHemoglobinuria
MyoglobinuriaMyoglobinuria
Back to our case studyBack to our case study……
Respiratory complication:Respiratory complication:
–– BipapBipap Oct 2 Oct 2 –– 44thth
–– ABG Oct 2:ABG Oct 2:
7.41 / 33 / 92 / 217.41 / 33 / 92 / 21
Pre intubation further Pre intubation further decompensationdecompensation::7.42 / 35 / 60 / 22 7.42 / 35 / 60 / 22
SatsSats: 88% with decrease to 20% during intubation : 88% with decrease to 20% during intubation
attemptsattempts
–– CXR : bilateral edemaCXR : bilateral edema
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Case study contCase study cont’’dd……
Required AC ventilation with paralysisRequired AC ventilation with paralysis
–– FentanylFentanyl; ; midazolammidazolam; ; propofolpropofol; & ; & rocuroniumrocuronium
AC : ARDS net protocol ventilation with trials of AC : ARDS net protocol ventilation with trials of
PSV for 8 daysPSV for 8 days
Hospital day 11: able to tolerate PSV ventilationHospital day 11: able to tolerate PSV ventilation
Hospital day 14: transfer to Seven Oaks Hospital Hospital day 14: transfer to Seven Oaks Hospital
ICUICU
–– PSV 20; peep 14PSV 20; peep 14
–– ABG: pO2 76; ABG: pO2 76; satssats 9494
CXR resultsCXR results
Oct 2: bibasilar pulmonary opacities Oct 2: bibasilar pulmonary opacities
with probable bilateral pleural with probable bilateral pleural
effusionseffusions
Oct 3: opacities predominate in Oct 3: opacities predominate in
mid/lower lungs; significant mid/lower lungs; significant
progression; pulmonary edemaprogression; pulmonary edema
Oct 4: @ 0830Oct 4: @ 0830-- no new changes; later no new changes; later
in dayin day-- R sided effusion; R sided effusion; intubatedintubated
CXR results contCXR results cont’’dd……
Oct 5: worsening L base R/T Oct 5: worsening L base R/T pulmpulm. .
Edema or ARDSEdema or ARDS
Oct 6: extensive alveolar Oct 6: extensive alveolar
consolidationconsolidation
Oct 10: extensive bilateral opacities Oct 10: extensive bilateral opacities
and consolidation; ARDSand consolidation; ARDS
Oct 11: increasing degree of Oct 11: increasing degree of
consolidationconsolidation
Culture ReportsCulture Reports
Oct 3: MSUOct 3: MSU-- >10*8 E. Coli>10*8 E. Coli
Oct 4: Oct 4:
–– SPT SPT -- 3+ PMN; 4+ GPC; 3+ GPB; 1+ GNB3+ PMN; 4+ GPC; 3+ GPB; 1+ GNB
–– ETT ETT –– 4+ PMN; 1+ GPB; 2+ GPC; 1+ GNB4+ PMN; 1+ GPB; 2+ GPC; 1+ GNB
Positive ETT secretions: strep pneumonia Positive ETT secretions: strep pneumonia & staph & staph aureusaureus
Temp did not elevate; WBC elevatedTemp did not elevate; WBC elevated
ABxABx: : cefuroximecefuroxime; ; cefotaximecefotaxime; ; azithromycinazithromycin; & ; & vancomycinvancomycin
Renal FunctionRenal Function
Scanty urinary output throughout hospital Scanty urinary output throughout hospital
staystay
LasixLasix usedused
On transfer: fluid balance +On transfer: fluid balance +veve: 17 L: 17 L
CreatinineCreatinine rise to 85 (admission 67)rise to 85 (admission 67)
No dialysis requiredNo dialysis required
Possible GI bleed (no source found)Possible GI bleed (no source found)
–– HgbHgb drop to 68drop to 68
CT CT abdabd: normal: normal
CT brain: normalCT brain: normal
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PatientPatient’’s final outcomes final outcome……
Transferred out of Seven Oaks ICU to Transferred out of Seven Oaks ICU to
general wardgeneral ward
Died November 15, 2007 due to Died November 15, 2007 due to
persistent pulmonary issuespersistent pulmonary issues
Conclusion: Near DrowningConclusion: Near Drowning
Effects on surfactant key to treatment Effects on surfactant key to treatment requirements and survival requirements and survival
Initial hypothermia may be protective to Initial hypothermia may be protective to CVS & neurological systemsCVS & neurological systems
Importance of water source debatable in Importance of water source debatable in regards to treatment & patient outcomeregards to treatment & patient outcome
Amount of water & length in elements Amount of water & length in elements more importantmore important
Be vigilantBe vigilant……..
Be preparedBe prepared……
ItIt’’s a matter of times a matter of time……
Appropriate, aggressive respiratory & Appropriate, aggressive respiratory &
multisystem support is the keymultisystem support is the key
•Be vigilant…
•Be prepared…
•It’s just a matter of
time…
•Appropriate,
aggressive respiratory
& multisystem support
is key
QUESTIONS ???QUESTIONS ???
Questions???
Conclusion: Near DrowningConclusion: Near Drowning
Effects on surfactant key to treatment Effects on surfactant key to treatment requirements and survival requirements and survival
Initial hypothermia may be protective to Initial hypothermia may be protective to CVS & neurological systemsCVS & neurological systems
Water source importance debatable on Water source importance debatable on outcome resultsoutcome results
Amount of water & length in elements Amount of water & length in elements more importantmore important