caspase-7

1

Caspase-7 Caspase-2 (Alexis) Caspase-6 (CST) cleaved Caspase-6 Caspase-9 Caspase-8 Lamin A/C 36 22 36 50 36 36 36 50 64 (kDa) STS - - + + - MCF-7 Lane 1 2 3 4 PARP p23 Caspase-6 siRNA (#6-3) + 22 50 64 16 98 Supplementary Figure 6

Upload: ruggiero-pender

Post on 31-Dec-2015

24 views

Category:

Documents

0 download

Report

Download

Embed Size (px):

DESCRIPTION

MCF-7. -. STS. +. -. -. +. +. Caspase-6 siRNA (#6-3). ( kDa). Caspase-9. 36. 36. Caspase-7. 22. 50. Caspase-2 (Alexis). 36. 36. Caspase-6 (CST). cleaved Caspase-6. 16. 64. Caspase-8. 50. 64. 50. Lamin A/C. 36. p23. 22. PARP. 98. 1 2 3 4. - PowerPoint PPT Presentation

TRANSCRIPT

Page 1: Caspase-7

Caspase-7

Caspase-2(Alexis)

Caspase-6(CST)

cleaved Caspase-6

Caspase-9

Caspase-8

Lamin A/C

36

22

36

50

36

36

36

5064

(kDa)

STS

- - ++

-

MCF-7

Lane 1 2 3 4

PARP

p23

Caspase-6 siRNA (#6-3)

+

22

50

64

16

98

Supplementary Figure 6

Caspase Independent/Dependent Regulation of K , Cell Shrinkage

Tumor-AssociatedAlterationsinCaspase-14Expressionin ... · caspase-8, caspase-9, and caspase-10, whereas inflammatory proteases include caspase-1, caspase-4, and caspase-5 (reviewed

Caspase-8 and Caspase-3 Are Expressed by Different ...Caspase-8 and Caspase-3 Are Expressed by Different Populations of Cortical Neurons Undergoing Delayed Cell Death after Focal Stroke

Smac mimetic‑induced caspase‑independent necroptosis

Equol enhances tamoxifen's anti-tumor activity by induction of caspase-mediated apoptosis in MCF-7 breast cancer cells

Reduced serpinB9-mediated caspase-1 inhibition can

0 4 8 12 24 48 (hr) Cleaved Caspase-9 Caspase-8 100 nM Paclitaxel MCF-7 Figure S1a

Kaposi's Sarcoma Herpesvirus microRNAs Target Caspase 3 and

Caspase-3 Activation an Indicator

Apoptosis. Cell death Necrotic Caspase-dependentCaspase-independent receptor-caspase 8 mitochondria-caspase 9 Classification of cell death

Caspase-3 feeds back on caspase-8, Bid and XIAP in …bogyolab.stanford.edu/pdf/FerreiraetalApoptosis.pdfKeywords Type I apoptosis Caspase-3 Caspase-8 Caspase inhibitor Feedback loop

Caspase-Glo 3/7 Assay -

Evolution of Apoptosis By Sean A. McMillan. What is Apoptosis? Programmed cell death (PCD) Several kinds – Caspase dependent – Caspase independent Ex:

Caspase-14 reveals its secrets

Silencing of Pokemon Enhances Caspase-Dependent Apoptosis via

Caspase-2 mediates a Brucella abortus RB51-induced hybrid … · death pathway remained unclear. In this study, we found that caspase-2 mediated In this study, we found that caspase-2

Supplemental Online Material Caspase-1–mediated pathway ... · Caspase-1–mediated pathway promotes generation . of thromboinflammatory microparticles . Andrea S. Rothmeier,

Reactive Oxygen Species Regulate Caspase Activation in ... · stream effector caspases. Our findings also provide direct evidence of TRAIL-induced caspase-3 activation in caspase-9–depleted

Nano-Pulse Stimulation induces immunogenic cell death in ... · Activation of combined caspase-3 and caspase-7 was assessed using the Caspase-Glo1 3/7 Assay (Promega). Following NPS

ProductDataSheet FullSize v4 · human Caspase-8, anti-human Caspase-8 polyclonal (rabbit) Detection Antibody, Anti-rabbit-IgG-HRP, Human Caspase-8 Standard lyophilized, 20.00 ng/ml

Supplemental Online Material Caspase-1–mediated pathway ...dm5migu4zj3pb.cloudfront.net/manuscripts/79000/79329/JCI79329sd.pdf · Caspase-1–mediated pathway promotes generation

Caspase-mediated apoptosis and caspase-independent cell ... · Alexis Biochemicals (San Diego, CA). Caspase-8/6 inhibitor [N-benzyloxycarbonyl-Ile-Glu(OMe)-Thr-Asp(OMe)-fluoromethyl

Induction of Caspase-9, Biochemical Assessment and

Apo-ONE Homogeneous Caspase-3/7 Assay - Please Select Your Country

Pro- Caspase 9 Fas FADD FLIP Pro- Caspase 8 Pro- Caspase 3 Bcl-2 p17 p12 Bid Bcl-X L Apoptose Smac/ Diablo Citocromo c dATP Apoptosoma Pro- Caspase 9 Caspases

Caspase-independent cell death.pdf

Death by caspase dimerization - Sarah H. (2012)

Apo-ONE(R) Homogeneous Caspase-3/7 Assay - Promega

Two mechanisms of caspase 9 processing in double-stranded ...BIB_426EB8A02047.P001/REF.pdf · ies against caspase 8 (1C12) and caspase 9 (p37-specific, p35-specific, and full length/p37/p35-specific)

Caspase-1 inhibitor ameliorates experimental autoimmune ... · Conclusions: Our results suggest that caspase-1 inhibitor ameliorates experimental autoimmune myasthenia gravis by innate

Caspase-9 and APAF-1 form an active holoenzymegenesdev.cshlp.org/content/13/24/3179.full.pdf · with APAF-1, that is, caspase-9 and APAF-1 form a ho-loenzyme in which caspase-9 is

Caspase-14: A novel caspase in the retina with a …Caspase-14: A novel caspase in the retina with a potential role in diabetic retinopathy Mohamed Al-Shabrawey,1,2,3 Saif Ahmad,2

Proinflammatory Caspase A Activation and an Antiviral

Loss of Caspase-1 and Caspase-3 Protein …...Caspase-3 is the ultimate executioner caspase that is essential for the nuclear changes associated with apoptosis, including chromatin