NUTRITIONUPDATES:

Presentedby:JulieBender-SibbioRDN,LD/N,cWCCertifiedFunctional&IntegrativeNutritionist

WhatyouNEEDtoknowtokeepyourBONES,GUT,&HEARTHealthy!

CeliacSupportGroup March18,2017

InterpretingNutritionInformation

MediaMarketingResearch

PhysicianHealthExperts

FriendsFamily

Experience

MagazinesJournals

PersonalizedMedicine/Nutrition

U • EachPersonisUnique – Noeatingstylefitseverybody

R • Goal:DetermineRootCauseoftheStruggle

A• AssessALLAreasofHealth– food,lifestyle,stress,genetics,hormones,health,sleep,exposure,beliefsystem,values

P • Partnership toImprovedHealthandOptimalhealth

P+ • Requirestime,mindfulness,andparticipation

Afunctionalandintegratednutritionapproach

MyworkasaCertifiedIntegrative&FunctionalNutritionistinvolves:

Today’sObjective:

• Tosharethemostcuttingedgeresearchrelatedtooneessentialnutrientthatcouldimpactyourhealth...fromheadtotoe

• Empoweryoutobeyourgreatesthealthadvocate

• Tosharemyprofessionalconcernswithmanyoutdatedrecommendationsforbonehealththatcouldleadtohealthrisk

• Todemonstratetheimportanceofaindividualized,comprehensive,andholisticapproachtooptimalhealth

• Tohavealivelyandinformativediscussion!

Answerquestionsrelatednutrition,celiacdisease,guthealthandmore….

Educate,Empower,Encourage,&Engage!

WhatImpactsYourBone&HeartHealth?

Stepstocareforyourbones&heart?

Howisthistiedtoyourgut?

CALCIUM VITAMIND WEIGHTTRAINING

SUPPLEMENTS BONEDENSITY

2017SurveyfromConsumerLabs

TOP5MostPopularSupplements:

1.VitaminD2.Fishoil3.CoQ104.Probiotics5.Multivitamins

Next5popular:6.B-vitamins

7.Magnesium

8.Curcumin/turmeric

9.Calcium

10.VitaminC

**Whatdoesthisimply?

Osteoporosis–anewepidemic?FACTS:

• 1/3womenovertheageof50experienceosteoporoticfractures• Osteoporosis-relatedfracturesareamajorpublichealthburden,estimatedat1.6millionfracturesperyear• Bonehealthismorethancalcium&VitaminD• Nutritionsupplementationcancauseharm

“Wemustunderstandthebiochemistrybehindnutrients,apersonshealthhistory/genetics,dietaryintakebeforewecanresponsibilityrecommend

supplementationandstepstoachieveoptimalbone,heart,andguthealth”~Julie

AnUnhealthyGutWillImpactBone!

ØMalabsorptive gutissuesareunabletoabsorbkeynutrients forbonehealth(ie.Calcium,VitaminD,Magnesium,vitaminK)

Ø ThegutistheonlyplacethatmanufacturesK2essentialforbonehealthØ Ifyoudon’thaveahealthgutflora(microbiome)youareunabletoeffectively:• SynthesizeVitaminsK,B9(folicacid),andB12• Reduceinflammation• Effectivelydetoxifythebody• Boostimmunesystem• Promotehealthydigestion

Ø Chronicinflammation=boneloss(Leakygut,dysbiosis,SIBO)• >95%oftheinflammationinthebodymaycomefromthegut.

STUDY:Probioticsmayhelpwithboneloss!

Calcium

• Itsroleandpurpose• Currentrecommendations

•Impactofage,diet,andmedications oncalciumabsorption

•Whatisthebestsource?Howwellisitabsorbed?

• Concerns,risks,andbenefits• Aresupplementsnecessaryifourbonesarenotimproving?SOURCES: Dairy, salmon, sardines, kale, broccoli, collards, mustard greens, turnip greens, tofu,

Chinese cabbage, sesame seeds, blackstrap molasses, calcium-fortified products

Doyouknowyourcalciumscore?

TimeMagazine2005

• Ischolesterolreallyagoodpredictor?• Only50%ofpeoplewhohave⬆cholesteroldevelopheartdisease.

• C-reactiveproteinandhomocysteine• Calciumscoreshowscalcificationwhichis#1riskfactorforCAD.

ü Excessivecalciumcanbuildupinthevesselsandstiffenthem,layingthefoundationforheartdisease.

ü StudiesshowthatatANYageifyouhaveahighervascularcalciumlevelyouareatrisk

WHYarewefindingcalciuminarteries?

Studied:Calciumsupplementationandimpactoncardiovascular

disease.Conclusion:“reassesstheroleofcalciumforthemanagementof

boneloss/osteoporosis”

BMJ 2010;341:c3691

2010

JournaloftheAmericanHeartAssociation– October2016

NEWSTUDY:“CalciumIntakeFromDietandSupplementsandtheRiskofCoronaryArteryCalcificationanditsProgressionAmongOlderAdults:10-yearFollow-upoftheMESAStudy”

Findings:*22%increaseinlikelihoodofdevelopingheartdiseaseoverthedecadeinpeoplewhousedcalciumsupplements.

WelcomeVitaminK2

• VitaminK1(Phylloquinone)canbefoundinleafygreenvegetables,suchasspinach,kale,collards,andbroccoli.Thegreenertheplant,thehigherthevitaminKcontent.

•VitaminK2-7(Menaquinone),istheformproducedbyintestinalbacteriaandalsoderivedfromputrefiedfishmeal,natto,fermentedcheeses.• NotfoundinourWesternculture

2FORMS(K2-4andK2-7)

VitaminK1 VitaminK2Forms Phylloquinone Menaquinone (MK-7)

MainSources Darkgreenveggies Natto or fermentedcheeses(notfoundinUSorWesternculture)

Halflifetime About1-2 hours About3daysMainuptake intissues

Hepatic(liver)tissue Bones andarteries

Role ClottingFactors Activation ofosteocalcin

VitaminK1andK2Comparison

HowVitaminKuptakeworks?

• Livertakes1st whatitneeds• RemainingKisleftforothertissues

• K-deficiencyoccursoutsidetheliverwithintissue• EffectsofVitaminKdeficiencyismostpronouncedinbone,cartilage,andarteries.

Whyandhow??

WithoutK2unabletoACTIVATEOsteocalcin

Bonesthriveonlywiththetrifecta– calcium,VitaminD3,andK2-7(Plusotheressentialnutrients)

Whatcangowrong?1. DeficiencyinVitaminD3=unabletoreleaseosteocalcin2. DeficiencyofVitaminK2= unabletoactivate“active”osteocalcin• OsteocalcinisdependentonVit.K2tocreatebonematrixupon

whichcalciumcrystallizes– itistheGLUEthatholdscalciuminthebone

• VitaminK2activatesosteocalcinthroughprocesscalled“carboxylation”

• IFvitaminK2isnotpresent= “undercarboxylated osteocalcin”(ucOC)=calciumisnotabletolaydownonbone– circulatesthroughbody…..

RESEARCH ALERT!!“High ucOC demontrated a 6-fold increase in fracture risk” Szulc etal.

Osteocalcin,BMD,FractureRateTheRESEARCH

Szulc etal: “ucOC inverselycorrelatedforBMD”

Knapen etal: “ucOC inverselycorrelatedwithBMD”

Vergnaud etal: “serumucOC predictshipfracture”

NaturalVitaminK2atMK-7fromNatto isEffective

v 2001- HighconsumptionofMK-7levelsfromnatto resultedinbetterlevelsofactivatedosteocalcinandreducedfracture

v 2006– natto consumptionhelpspreventthedevelopmentofosteoporosis

v 2008– Yaegashi demonstratedthatbettervitaminKstatusattributedtoNatto resultedinthereductionofhipfracturerisk

WhatelsecanVitaminK2-7foryourbones?

1. Estrogendepletion=bonelossduetobonereabsorption.(releasescalciumfromthebone=bonelossinmenopause)VitaminK2-7hasbeenfoundtoINHIBIT(prevent)reabsorptionofbone!

2. WithadequatenutrientsandK2-7itcanhelp:• Slowdownlossofbone• Rebuildbone

ConcernswithHypervitaminosis D:1. IncreasecalcificationalloverthebodyifDisreleasing

osteocalcin– extraOsteocalcinisusingupalltheVitaminK2foractivationofVitaminD!

VitaminKandVascularHealth

Objective:TostudytheassociationofdietaryintakeofK1andK2withaorticcalcification,CVD,andtotaldeath.

Geleijnse etal.JournalofNutrition2004

K2andCardiovascularDisease

ResultsofStudy:CONCLUSIONS:Whenconsumingdaily45ugdietaryK2-7 youhave:

§ 50% reduction of arterial calcification

§ 50% reduction of cardiovascular health

§ 25% reduction of all cause mortalityAscomparedtolowintakeofdietaryK2

TherewasNOcorrelationwithvitaminK-1inthisstudy!

AdditionallyClinicallyProvenIndications….

• VitaminK2-7showntoreducediabetesriskby20% inaDutchpopulationstudyover10years(38,000patients)

• VitaminK2-7showntodecreasecancerrisk(ingeneral).Studyon23,000Germanadults.ShowedhigherK2intakeassociatedwithlowerlikelihoodofdevelping anddyingofcancer.

NEWDISCOVERIESONTHEHORIZON

• FunctioninMuscleContraction

• FunctioninNerveHealth• FunctioninMitochondria

• FunctioninCardiacFunctionandOutput.

K2-7 maybecomethemostimportantAntiAging Nutrient?

Agingisafactorofmitochondrialhealth,cardiacoutput,andvascularhealth.

Ø Removescalciumfromarteries(onlythingnatural!)

Ø Slowsdownprogressionofdiabetes

Ø Everycellinthebodygetsmorenutrientsandbloodsupply

Ø Increasesmitochondrialfunction,soeachcellcanproducemoreenergyandwecanregeneratedyingcells

Ø Preventsagingrelatedtissuedegeneration

It is proposed that likely ALL of us may be sub-clinically deficient in this key nutrient!

Howmuchisrequired?

• ThereisNOtoxicity• Takeinconjunctionwithco-factorsforoptimalabsorption

• AvoidChinesesourceofK2-7• PrescriptionisofferedinItaly,Poland,IndiaONLYProductknownontheMarketisMegaQUINONE K-7• ONLYpharmaceuticalgradewithnaturalvitaminK2-7with320mg• ONLYsupplementthatcontainschelatedmineralsthatareessentialK2-cofactors• Soy,allergen,dairy,gluten,andnon-GMO(Kosher/Vegan)• NOTrecommendedforthoseonbloodthinningmedications

❋100-300mcgissupportedintheliterature

Observations,Conclusions,Considerations:

•VitaminK2-7:missingnutrientinbone& hearthealth!?• Considerinthepreventionandtreatment• Maygomuchfurtherthanthis- overallhealth!

•Cautionshouldbeusedwithcalciumsupplementation-foodsourcesarepreferred• ItisestimatedthataveragepersoninUSconsumes~700mgcalciumday• Foodfoodlabels• IfyouDOtakecalcium,dosoindivideddosesinawell-assimilatedform• Avoidfoodsthatimpactabsorptionofcalciumwhentakingsupplements

•VitaminDlevelsshouldbemonitoredannuallyandaddressedtodeterminecauseandpropertreatment.

Observations,Conclusions,Considerations:

• Comprehensivenutritionplanmustbetailoredtobonehealth• essentialnutrients(protein,calcium,VitaminD,magnesium,VitaminA,K,boron)andsupportingnutrients(B6,B12,folicacid,VitaminC)

• UnderstandthatjustbecauseyouhavegoodBMDthatitisnotalwaysapredictorofstronghealthybonesfromtheinside.

• Discusswithphysiciantheimpactofmedicationonnutrientabsorptionandutilization(EspeciallyPPI’s,chronicuseofantibiotics.)

• ExerciseandLifestylehabits• EACHpersonisunique.“Osteoporosis:animbalanceinthebody’schemistry.BoneLossisa

directcooralation withyourbiochemistry”

Julie’sResearchBasedProtocolforOsteoporosis

1. Diet:Avoidrefinedsugar.Avoidexcessiveintakeofcaffeine,colabeverages,andsodiumchloride.Testforceliacdiseaseinpatientswithunexplainedosteoporosis.Considerinvestigatingfoodallergiesinselectedcases.Considereatingdriedplums

2. Environment:Attempttominimizeexposuretoaluminum,lead,cadmium,andtin.

3. Calcium:600–1,200mg/day.(preferablynon-dairysourcesformost– supplementsasindicated)

4. VitaminD:800-2000IU/day5. Magnesium:300–600mg/day6. VitaminK:100–1,000μg/dayofvitaminK1.VitaminK2-7 atadoseof

100-300mg/day .(Menaqinone-4atadoseof45mg/daymaybeconsideredinselectedcases.)

Julie’sResearchBasedProtocolforOsteoporosis

7.Probioticandprebioticfoods – optimizeguthealth.

8.Additionalsupportivenutrients(dailydosesinparentheses):vitaminB6 (10–25mg),folicacid(0.4–5.0mg);vitaminB12 (20–1000μg),vitaminC(100–500mg),zinc(10–30mg),copper (1–3mg),manganese(3–20mg),boron (1–3mg),silicon(1–5mg),strontium (2–6mg).

9.Strontium:170–680mg/dayonlyselectedcases.Consideradosagereductionorstoppingafter1yr.Basedonnewresearchmaynotbeindicated.

10.Hormone-replacementtherapy:DHEA,estrogens,progesterone,andtestosterone(individuallyorinvariouscombinations)(perMD)

Gaby,AlanR.,M.D..NutritionalMedicine(SecondEdition).AlanR.Gaby,M.D.,04/2017.VitalBookfile.*Over300referencesavailableuponrequest.

FoodforThought……

“Achieving Optimal Health is a complex interplay between your “one of a kind genes”, dietary intake, biochemistry, metabolism, hormones, emotions, exercise, stress, sleep, exposure to toxins, inflammation, and belief system.”

Youmaye-mailmeforacopyofthispresentation.

JulieBender-SibbioRDN,LDN,cWC

www.jbsnourishwell.com julie@jbsnourishwell.com

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