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    Leukocyte adhesion deficiency

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    Leukocyte adhesion deficiency

    Leukocyte adhesion deficiency(LAD), is arare autosomalrecessive disorder characterizedbyimmunodeficiencyresulting in recurrentinfections Leukocyteadhesion deficiencyis divided into at least twosubtypes: LAD1 and LAD2.

    The classic descriptions of LAD included recurrent bacterialinfections,defects in neutrophiladhesion, and a delay in umbilicalcordsloughing. The defects in adhesion result inpoor neutrophilchemotaxis, phagocytosis, as well as neutrophilia .

    Individuals with LAD suffer from bacterialinfections beginning inthe neonatalperiod. Infections suchas omphalitis, pneumonia, gingivitis, and peritonitis are common and

    often life-threatening due to the infant's inability to properly destroythe invading pathogens.These individuals do not form abscess becausegranulocytes cannot migrate to the sites of infection.

    http://en.wikipedia.org/wiki/Autosomehttp://en.wikipedia.org/wiki/Dominance_(genetics)http://en.wikipedia.org/wiki/Immunodeficiencyhttp://en.wikipedia.org/wiki/Immunodeficiencyhttp://en.wikipedia.org/wiki/Immunodeficiencyhttp://en.wikipedia.org/wiki/Immunodeficiencyhttp://en.wikipedia.org/wiki/Dominance_(genetics)http://en.wikipedia.org/wiki/Infectionhttp://en.wikipedia.org/wiki/Immunodeficiencyhttp://en.wikipedia.org/wiki/Infectionhttp://en.wikipedia.org/wiki/Leukocyte_adhesion_deficiency-1http://en.wikipedia.org/wiki/Leukocyte_adhesion_deficiency-2http://en.wikipedia.org/wiki/Leukocyte_adhesion_deficiency-1http://en.wikipedia.org/wiki/Leukocyte_adhesion_deficiency-2http://en.wikipedia.org/wiki/Neutrophilhttp://en.wikipedia.org/wiki/Cell_adhesionhttp://en.wikipedia.org/wiki/Umbilical_cordhttp://en.wikipedia.org/wiki/Umbilical_cordhttp://en.wikipedia.org/wiki/Bacteriahttp://en.wikipedia.org/wiki/Infectionhttp://en.wikipedia.org/wiki/Umbilical_cordhttp://en.wikipedia.org/wiki/Neutrophilhttp://en.wikipedia.org/wiki/Cell_adhesionhttp://en.wikipedia.org/wiki/Cell_adhesionhttp://en.wikipedia.org/wiki/Umbilical_cordhttp://en.wikipedia.org/wiki/Umbilical_cordhttp://en.wikipedia.org/wiki/Neutrophilhttp://en.wikipedia.org/wiki/Chemotaxishttp://en.wikipedia.org/wiki/Phagocytosishttp://en.wikipedia.org/wiki/Phagocytosishttp://en.wikipedia.org/wiki/Phagocytosishttp://en.wikipedia.org/wiki/Neutrophilhttp://en.wikipedia.org/wiki/Chemotaxishttp://en.wikipedia.org/wiki/Phagocytosishttp://en.wikipedia.org/wiki/Neutrophiliahttp://en.wikipedia.org/wiki/Neonatehttp://en.wikipedia.org/wiki/Bacteriahttp://en.wikipedia.org/wiki/Infectionhttp://en.wikipedia.org/wiki/Omphalitishttp://en.wikipedia.org/wiki/Omphalitishttp://en.wikipedia.org/wiki/Omphalitishttp://en.wikipedia.org/wiki/Pneumoniahttp://en.wikipedia.org/wiki/Gingivitishttp://en.wikipedia.org/wiki/Omphalitishttp://en.wikipedia.org/wiki/Pneumoniahttp://en.wikipedia.org/wiki/Gingivitishttp://en.wikipedia.org/wiki/Peritonitishttp://en.wikipedia.org/wiki/Pathogenhttp://en.wikipedia.org/wiki/Pathogenhttp://en.wikipedia.org/wiki/Pathogenhttp://en.wikipedia.org/wiki/Peritonitishttp://en.wikipedia.org/wiki/Gingivitishttp://en.wikipedia.org/wiki/Pneumoniahttp://en.wikipedia.org/wiki/Omphalitishttp://en.wikipedia.org/wiki/Neonatehttp://en.wikipedia.org/wiki/Infectionhttp://en.wikipedia.org/wiki/Bacteriahttp://en.wikipedia.org/wiki/Neutrophiliahttp://en.wikipedia.org/wiki/Phagocytosishttp://en.wikipedia.org/wiki/Chemotaxishttp://en.wikipedia.org/wiki/Neutrophilhttp://en.wikipedia.org/wiki/Cell_adhesionhttp://en.wikipedia.org/wiki/Umbilical_cordhttp://en.wikipedia.org/wiki/Umbilical_cordhttp://en.wikipedia.org/wiki/Cell_adhesionhttp://en.wikipedia.org/wiki/Neutrophilhttp://en.wikipedia.org/wiki/Infectionhttp://en.wikipedia.org/wiki/Bacteriahttp://en.wikipedia.org/wiki/Leukocyte_adhesion_deficiency-2http://en.wikipedia.org/wiki/Leukocyte_adhesion_deficiency-1http://en.wikipedia.org/wiki/Infectionhttp://en.wikipedia.org/wiki/Immunodeficiencyhttp://en.wikipedia.org/wiki/Dominance_(genetics)http://en.wikipedia.org/wiki/Autosome

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    CANCER

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    CANCER Cancer is a complex group of diseases with many

    possible causes.

    causes of cancer, including genetic factors; lifestylefactors such as tobacco use, diet, and physical activity;certain types of infections; and environmentalexposures to different types of chemicals and

    radiation. Metastasis is the spread of tumor in the body

    Changes the number of cell and types of varios celladhesion molecule.

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    Yesinia INFECTION

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    Yesinia infection Caused by enteric pathogen yersenia pseudotubercolosis

    result to gastroentiritis with diarrhea. Yersiniosis is aninfectious disease caused by a bacterium of the

    genus Yersinia. Common symptoms in children are fever,abdominal pain, and diarrhea, which is often bloody.Symptoms typically develop 4 to 7 days after exposure andmay last 1 to 3 weeks or longer. In older children and adults,right-sided abdominal pain and fever may be the

    predominant symptoms, and may be confused withappendicitis. In a small proportion of cases, complicationssuch as skin rash, joint pains, or spread of bacteria to thebloodstream can occur.

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    Shigella infection

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    Shigella infection Shigellosis is an infectious disease caused by a group of

    bacteria calledShigella. The Shigella bacteria pass fromone infected person to the next.

    It attaches to an integrin () via protein on its surfacecausing in dysentery and is usually caused bycontaminatio of food.

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    Listeria infection

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    Listeria infection Caused by listeria monocytogenesis. Listeria monocytogenes is ubiquitous in the environment.

    The main route of acquisition ofListeria is through theingestion of contaminated food products. Listeria has beenisolated from raw meat, dairy products, vegetables, fruitand seafood. Soft cheeses, unpasteurized milk andunpasteurised pt are potential dangers; however, someoutbreaks involving post-pasteurized milk have beenreported.[1]

    Rarely listeriosis may present as cutaneous listeriosis. Thisinfection occurs after direct exposure to L.monocytogenes by intact skin and is largely confinedtoveterinarians who are handling diseased animals, mostoften after a listerial abortion

    http://en.wikipedia.org/wiki/Listeria_monocytogeneshttp://en.wikipedia.org/wiki/Seafoodhttp://en.wikipedia.org/wiki/Cheesehttp://en.wikipedia.org/wiki/Seafoodhttp://en.wikipedia.org/wiki/Cheesehttp://en.wikipedia.org/wiki/P%C3%A2t%C3%A9http://en.wikipedia.org/wiki/Cheesehttp://en.wikipedia.org/wiki/P%C3%A2t%C3%A9http://en.wikipedia.org/wiki/Pasteurizationhttp://en.wikipedia.org/wiki/Listeriosishttp://en.wikipedia.org/wiki/Pasteurizationhttp://en.wikipedia.org/wiki/Listeriosishttp://en.wikipedia.org/wiki/Cutaneoushttp://en.wikipedia.org/wiki/Veterinarianshttp://en.wikipedia.org/wiki/Veterinarianshttp://en.wikipedia.org/wiki/Veterinarianshttp://en.wikipedia.org/wiki/Cutaneoushttp://en.wikipedia.org/wiki/Listeriosishttp://en.wikipedia.org/wiki/Pasteurizationhttp://en.wikipedia.org/wiki/P%C3%A2t%C3%A9http://en.wikipedia.org/wiki/Cheesehttp://en.wikipedia.org/wiki/Seafoodhttp://en.wikipedia.org/wiki/Listeria_monocytogeneshttp://en.wikipedia.org/wiki/Listeria_monocytogeneshttp://en.wikipedia.org/wiki/Listeria_monocytogenes

The Cell and its Environment: The processes behind the movement of substances in and out of cells

Chap. 5: Homeostasis and the Cell Membrane --- Homeostasis – steady state of balance between a cell and its environment

Cell Membrane! Diffusion and osmosis. The cell membrane Separates the cell from its surrounding environment Controls movement of materials into and out

The Plasma Membrane. Function Separate the cell from its environmentSeparate the cell from its environment Control the traffic that enters & exits the

NASC 1 - Cell and Its Environment

Ferrel cell Ferrel cell Ferrel cell Hadley cell Ferrel cell Polar cell The Physical Environment Image from NASA

THE CELL AND ITS ENVIRONMENT. HOMEOSTASIS Homeostasis- “ steady state” or balance cells constantly seek homeostasis The Cell Membrane is responsible for

Cellular Processes. THE CELL IN ITS ENVIRONMENT 1. How do small substances move into and out of the cell? Diffusion Diffusion Osmosis Osmosis Active

The Cell in Its Environment

Cell Structure and Function - The Cell in Its Environment Do Now: How is the cell membrane shown below like a colander? Homework: 1. The cell in its environment

Unit 3B Cell Membrane & Transport. What is Cell Transport? Transport- the movement of materials between an organism and its environment Cellular Transport-

Chapter 8. The boundary between the cell and its environment Controls what enters and exits the cell (selective permeability) - nutrients, wastes,

Diffusion & Osmosis. Cell exist in a constantly changing environment. Homeostasis: Biological balance, or stability that a cell maintains with its environment

Cell-Environment Interaction (outside-in)

Cell & Its Orgenells

Basic Cell Structure. Cell Membrane a thin layer of lipid and protein that separates the cells contents (insides) from its environment (outsides). **The

Chapter 2, Section 2 The Cell in Its Environment Monday, October 5, 2009 Pages 56 -- 60

The Cell & Its Environment

Bi 1a Cell Membrane Structure and Function Cells need an inside & an outside… separate cell from its environment cell membrane is the boundary

Diffusion and Osmosis: How does stuff get into and out of a cell? The Cell in its Environment Ch 7, Section 2 L3 Biology

WHAT IS A CELL MEMBRANE? · The cell membrane is the boundary between a living cell and its outside environment. It is also responsible for regulating what molecules pass into and

Cell Growth, Regulation and Hormones. Levels of Cell Regulation Intracellular – Within the individual cells Local Environment – Cells response to its

Cell Membrane n The cell membrane or plasma membrane completely surrounds the cell and serves as a barrier between the cell and its environment. n Allows

Chemical Compounds in Cells and The Cell in its Environment

Chemical Compounds in Cells and The Cell in its Environment

The Cell and Its Environment Spring 2010. What is a cell? A cell is the basic unit of living things. Some living things are composed of only one cell

The Cell and Its Environment Fall 2010 What is a cell? A cell is the basic unit of living things. Some living things are composed of only one cell and

Eukaryotic Cell Structure 7.2 Biology Mr. Hines Comparing the cell to a factory In order for a cell to maintain its internal environment (homeostasis),

UNIT 3: The Cell and its Environment Biology I DAYSHEET 49 ...biomonsters.weebly.com/uploads/8/5/4/6/8546703/ds49_dna_replica… · UNIT 3: The Cell and its Environment Biology I

Support Protection controls movement of materials in/out of cell barrier between cell and its environment maintains homeostasis Analogy: City

The cell and its environment. The cell within the organism

Cells & Cell Organelles€¦ · CELL MEMBRANE Cells need an inside & an outside… separate cell from its environment cell membrane is the boundary made up of a phospholipid bi-layer

The Cell Culture Environment

In & Out of Cells (The Cell In Its Environment) Passive TransportActive Transport

Unit 4: The Cell & Its Environment