Cellular biology-Why do we need to know this?

Bushong

When an atom is ionized

Chemical binding properties changein large molecules: breakage or

relocation of molecules…become abnormal

Abnormal meansFunction improperlycease to function -impairment or

death of cell

Damage is Reversible

Ionized atoms become neutral…How?

Molecules are mended by repair enzymes

Immediate response to radiationLatent response(Bushong) see Box 32-1

RADIATION INTERACTS AT ATOMIC LEVEL

Atoms combine to form moleculesThe body is made of macromoleculesWhat is the definition of

macromolecules?

With this kind of potential damage….

The government tends to get involvedCHAPTER 9 SHERER

YOU ARE RESPONSIBLE FOR DIFFERENTIATING BETWEEN

ICRPNCRPUNSCEARNAS/NRC-BEIRNRCEPAFDAOSHA

What is the smallest element of protoplasm?

The cell

Which of the following macromolecules contain enzymes for repair?

A) protein b) lipidsc) carbs d) nucleic acids

MORE QUESTIONS

_____provides most of the cell’s energy

DNA and RNA are two types of these

What is function of lipids

Carbohydrates

Nucleic acids

store energy component of membrane protects against cold and

heat assists in digestive process components of substances

such as hormones

Tissues are groups of ?

Organs are groups of ?

System is a group of?

An organism is?

Cells

tissues

organsa human

CELLULAR ANATOMY

RibosomesMitochondriaEndoplasmic ReticulumLysosomesGolgi Apparatus

RADIATION BIOLOGY

CHAPTER 6..an introduction-What do you already know?

DO YOU REMEMBER BERGONIE AND TRIBONDEAU?

Pg 102 (Sherer)

TWO TYPES OF CELLS

Somatic

Germ

MALIGNANT CELLS

Divide abnormallyincreased amount of chromatinincreased amount of nuclear

materialnormal cells stay together (tissue)some malignant cells break away to

other tissues

Direct effect

Where do you think the radiation hits to be given this name?

INDIRECT EFFECT

What molecule to you think radiation hits?

Most interactions occur hereForms free radicals which are

chemical components that damage cells

Free radicals are a result of radiolysis of water

FRACTIONATION

Dividing a dose of radiation into small amounts over a given time

PROTRACTED DOSE

Dose delivered continuously but at a lower rate