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Page 1: CENTRIFUGAL ECMO SYSTEMS - Vanderbilt University … TO...energy using centrifugal force of ... Centrifugal Centrifugal pumps are non – occlusive pumps which operate on ... CENTRIFUGAL
Page 2: CENTRIFUGAL ECMO SYSTEMS - Vanderbilt University … TO...energy using centrifugal force of ... Centrifugal Centrifugal pumps are non – occlusive pumps which operate on ... CENTRIFUGAL

ECMO

Page 3: CENTRIFUGAL ECMO SYSTEMS - Vanderbilt University … TO...energy using centrifugal force of ... Centrifugal Centrifugal pumps are non – occlusive pumps which operate on ... CENTRIFUGAL

Biomedicus 550 Centrifugal pump

Page 4: CENTRIFUGAL ECMO SYSTEMS - Vanderbilt University … TO...energy using centrifugal force of ... Centrifugal Centrifugal pumps are non – occlusive pumps which operate on ... CENTRIFUGAL

Terumo

Page 5: CENTRIFUGAL ECMO SYSTEMS - Vanderbilt University … TO...energy using centrifugal force of ... Centrifugal Centrifugal pumps are non – occlusive pumps which operate on ... CENTRIFUGAL

Jostra Roto flow

Page 6: CENTRIFUGAL ECMO SYSTEMS - Vanderbilt University … TO...energy using centrifugal force of ... Centrifugal Centrifugal pumps are non – occlusive pumps which operate on ... CENTRIFUGAL

Sorin Revolution

Page 7: CENTRIFUGAL ECMO SYSTEMS - Vanderbilt University … TO...energy using centrifugal force of ... Centrifugal Centrifugal pumps are non – occlusive pumps which operate on ... CENTRIFUGAL

Combo system Stand alone system

Page 8: CENTRIFUGAL ECMO SYSTEMS - Vanderbilt University … TO...energy using centrifugal force of ... Centrifugal Centrifugal pumps are non – occlusive pumps which operate on ... CENTRIFUGAL

Priming Volume 57ml

Maximum Flow Rate 8lpm

Maximum Outlet Pressure 800

Inlet/Outlet Port 3/8 in. (9.5 mm)

Pump Casing Polycarbonate

Minimal surface area

Large wash out holes

Low blood transit time

No stagnant areas

Low heat generation

Lower shear

Excellent air handling ability

Page 9: CENTRIFUGAL ECMO SYSTEMS - Vanderbilt University … TO...energy using centrifugal force of ... Centrifugal Centrifugal pumps are non – occlusive pumps which operate on ... CENTRIFUGAL

600

650

700

750

800

850

900

950

1000

0 2 4 6 8

LPM

mm

Hg

Revolution 3500 BP80 Sarns

Terumo Jostra Isoflo

0

100

200

300

400

500

600

700

800

900

0 1000 2000 3000 4000 5000

RPM

mm

Hg

Revolution

BP-80

Isoflow

Rotaflow

Capiox

Sarns

Page 10: CENTRIFUGAL ECMO SYSTEMS - Vanderbilt University … TO...energy using centrifugal force of ... Centrifugal Centrifugal pumps are non – occlusive pumps which operate on ... CENTRIFUGAL

Roller

Able to set totally or Partially occlusive

Positive displacement – pushes blood by squeezing raceway

Flow = (stroke volume x rpms

Flow is not dependent on resistance

Non – occlusive

Passive displacement

Cones or impellers create kinetic energy using centrifugal force of fluid constrained vortexing

Rpm’s are proportional to resistance

Flow is inversely proportional to resistance

Centrifugal

Page 11: CENTRIFUGAL ECMO SYSTEMS - Vanderbilt University … TO...energy using centrifugal force of ... Centrifugal Centrifugal pumps are non – occlusive pumps which operate on ... CENTRIFUGAL

Centrifugal pumps are non – occlusive pumps which operate on the principle of entraining blood into the pump by a vortexing action of spinning impeller blades or rotating cones.

The impellers or cones are magnetically coupled with an electric motor and, when rotated rapidly, generate a pressure differential that causes the movement of blood.

Page 12: CENTRIFUGAL ECMO SYSTEMS - Vanderbilt University … TO...energy using centrifugal force of ... Centrifugal Centrifugal pumps are non – occlusive pumps which operate on ... CENTRIFUGAL

Unlike roller pumps, they are totally non-occlusive.

They are preload and afterload dependant; i.e., an increase in downstream resistance decreases forward flow delivered to the patient. This has both favorable and unfavorable consequences.

Flow is not determined by rotational rate alone, so a flow meter must be incorporated in the arterial outflow to quantitate pump flow.

Page 13: CENTRIFUGAL ECMO SYSTEMS - Vanderbilt University … TO...energy using centrifugal force of ... Centrifugal Centrifugal pumps are non – occlusive pumps which operate on ... CENTRIFUGAL

When the pump is connected to the patient’s arterial system but is not running, blood will flow backward through the pump and out of the patient unless the arterial line is clamped. This can cause reverse flow (left to right shunt),

exsanguination of the patient or aspiration of air into the arterial line (e.g., from around the purse string sutures).

Thus, whenever the centrifugal pump is not running, the arterial line MUST be clamped!

Page 14: CENTRIFUGAL ECMO SYSTEMS - Vanderbilt University … TO...energy using centrifugal force of ... Centrifugal Centrifugal pumps are non – occlusive pumps which operate on ... CENTRIFUGAL

Centrifugal pumps Flow is dependent on

Rpm’s

After load

Pre Load

With limitation of Rpm’s, centrifugal pumps decrease risk of over pressurization and cavitation.

Page 15: CENTRIFUGAL ECMO SYSTEMS - Vanderbilt University … TO...energy using centrifugal force of ... Centrifugal Centrifugal pumps are non – occlusive pumps which operate on ... CENTRIFUGAL

Attention should be paid to line pressures and rpm’s upon establishment of full flow Deviations of the various values will indicate

appropriate actions to maintain full flow. Increased Afterload – Decreased flow

Decreased Afterload – Increased flow

Increased Preload – Increased flow

Decreased Preload – Decreased flow

Page 16: CENTRIFUGAL ECMO SYSTEMS - Vanderbilt University … TO...energy using centrifugal force of ... Centrifugal Centrifugal pumps are non – occlusive pumps which operate on ... CENTRIFUGAL

Assemble circuit using sterile technique.

Circuit must be completely gravity primed. 1. Plasmalyte bag hanging on IV pole

2. Entire circuit on floor except oxygenator

3. Oxygenator on oxygenator holder

4. Open stopcock to allow plasmalyte to flow

5. Open stopcock on oxygenator to allow air to escape

6. Ensure air moves with plasmalyte

7. Ensure “cone” is completely primed

8. Ensure oxygenator is completely primed and circuit de-aired

Page 17: CENTRIFUGAL ECMO SYSTEMS - Vanderbilt University … TO...energy using centrifugal force of ... Centrifugal Centrifugal pumps are non – occlusive pumps which operate on ... CENTRIFUGAL

Circuit placement 1. Circuit extends from pt as usual

2. Cone sits in the centrifugal head with the outlet pointed down.

3. Oxygenator in holder as standard

4. Circuit loops up from oxygenator and down thru bubble detector

5. Circuit goes down thru ERC approx 12” after bubble detector

6. Circuit goes back to pt as usual

7. Filter the circuit as usual

Page 18: CENTRIFUGAL ECMO SYSTEMS - Vanderbilt University … TO...energy using centrifugal force of ... Centrifugal Centrifugal pumps are non – occlusive pumps which operate on ... CENTRIFUGAL

Blood prime as usual

Wait for Surgeon to cannulate …………… zzzzz

Once loop is handed off, before circuit is cut place a clamp on outlet side of cone.

Keep RPM’s @ 1000.

When surgeon give’s the go ensure ERC is open, slowly remove clamp from arterial limb.

Increase RPM’s while watching flow and pressures until desired flow achieved.

Continue to monitor pressures and flows