cervical incompetence moh abdalla

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    Dr.Mohammed AbdallaDr.Mohammed AbdallaDomiat general hospitalDomiat general hospital

    cervicalcervical

    incompetenceincompetence

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    Cervical incompetence isCervical incompetence is

    defined as thedefined as the inability toinability tosupport pregnancy tillsupport pregnancy till

    termterm

    because of a functional orbecause of a functional orstructural defect of thestructural defect of the

    cervixcervix

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    Although the efficacy of cerclage for

    cervical incompetence

    has never been fully confirmedin randomized clinical trials ,the role

    of cerclage has been expanded toinclude women with risk factors for

    spontaneous preterm birth or

    nonreassuring sonographic cervicalfindings in the mid trimester.

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    So, before you send your

    patient to the theater forcerclage your diagnosis

    necessities solid criteriaotherwise many will be

    unduly done.

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    But unfortunately there isBut unfortunately there is

    no consensus about theno consensus about thecervical cut off lengthcervical cut off length

    < 25mm< 25mm

    OrOr< 15mm< 15mm

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    the cervical cut offthe cervical cut off

    length inlength in singletonsingletonpregnancypregnancy

    Cannot be applied inCannot be applied in

    multiplemultiple pregnancy?pregnancy?

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    As the risk with CL

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    Inconsensus about cutoff

    cervical length will resultin the categorization of 5%

    to 10% of pregnant womenas having a short cervix.

    problem

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    As any controversialAs any controversial

    issue we have hereissue we have herewhite and black faceswhite and black faces

    but always within thebut always within thegrey zone, which lies ingrey zone, which lies in

    between, we fall inbetween, we fall indoubt.doubt.

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    White face here is thehere is thewomen withwomen with

    irrelevant obstetricirrelevant obstetricand gynecologicaland gynecological

    history, ashistory, as they needthey needno screening.no screening.

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    The black face of the problem isof the problem isrepresented by those who haverepresented by those who have

    three or more midtrimesterthree or more midtrimester

    losses or preterm births , thelosses or preterm births , thedecision isdecision is

    a prophylactic cerclage performeda prophylactic cerclage performedat 13 to 16 weeksat 13 to 16 weeks

    of gestationof gestation ..

    2

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    The grey zone isrepresented here by those

    women of low or moderaterisk, and they need serial

    ultrasound screening bytransvaginalultrasonography.

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    Ultrasound screeningUltrasound screening

    if we are going to screen this group ofif we are going to screen this group of

    patients with mild to moderate risk :patients with mild to moderate risk :

    when to start?when to start?what is the ultrasonic criteriawhat is the ultrasonic criteria

    of incompetent cervix?of incompetent cervix?and when to intervent?and when to intervent?

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    when to startwhen to start

    TVS should not begin

    before 16 weeksas the upper portion of the

    cervix is not easily

    distinguished

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    ultrasonic criteria ofultrasonic criteria of

    incompetent cervixincompetent cervixMake sure to use proper technique.Make sure to use proper technique.

    Knowing what to measure .Knowing what to measure .Know what's normal, and what'sKnow what's normal, and what's

    abnormal .abnormal .

    Linking cervical assessment toLinking cervical assessment to

    gestational age .gestational age .

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    proper technique

    patients are asked to empty their bladder .patients are asked to empty their bladder .You should identify at the same sagittalYou should identify at the same sagittal

    view the internal os, external os, cervicalview the internal os, external os, cervical

    canal, and endocervical mucosa.canal, and endocervical mucosa.the probe is slowly withdrawn to avoidthe probe is slowly withdrawn to avoid

    false elongation of the cervix.false elongation of the cervix.

    The cervical length is measured byThe cervical length is measured byfreezing the screen three separate timesfreezing the screen three separate times

    with no more than 2 to 3 mm variations.with no more than 2 to 3 mm variations.

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    proper technique

    To recognize funneling the walls of the funnelTo recognize funneling the walls of the funnelare formed by endocervical mucosa.are formed by endocervical mucosa.

    If the cervical canal is sometimes curved,If the cervical canal is sometimes curved,

    therefore, cervical length should be determinedtherefore, cervical length should be determined

    by tracing the length of the cervix or by addingby tracing the length of the cervix or by addingthe sum of two straight sections.the sum of two straight sections.

    Apply transfundal pressure for 15 seconds,Apply transfundal pressure for 15 seconds,

    and record any changes in cervical length orand record any changes in cervical length or

    funneling. cervical stress test .funneling. cervical stress test .

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    cm 2

    1.5

    1.2

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    cervical stresscervical stresstesttest

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    the walls of the funnel are formed by

    endocervical mucosa.

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    what's normalwhat's normal

    In low-risk women, CL duringIn low-risk women, CL during

    pregnancy has a mean ofpregnancy has a mean of35 to 4035 to 40

    mm from 14 to 30 weeksmm from 14 to 30 weeks..the lower 10th percentile beingthe lower 10th percentile being

    25 mm and the upper 10th (90th25 mm and the upper 10th (90th

    percentile) 50 mmpercentile) 50 mm..

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    3812521998Heath et al

    421751997Tongsong et al

    41411996Cook et al

    3529151996Iams et al

    371061995Iams et al

    421541994Zorzoli et al

    371771993Murakawa et al

    42771991Andersen et al

    48241990Kushnir et al

    411251990Andersen et al

    48801988Podobnik et al

    521501988Ayers et alCervical Length (mm)NYearReference

    CERVICAL LENGTH (MEAN OR MEDIAN) IN LOW-RISK POPULATIONS IN MIDTRIMESTER

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    9747998151424Hassan etal

    995299581523Heath et al

    99391006251822Taipale etal

    97269723

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    Low %PPV meansLow %PPV means

    that many unduethat many undue

    cerclages werecerclages were

    done.done.

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    high %NPV meanshigh %NPV meansthat the test isthat the test is

    reassuring whenreassuring when

    negative.negative.

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    So we cannot rely onSo we cannot rely oncervical lengthcervical length

    alone as a predictoralone as a predictor

    of incompetenceof incompetence

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    the progressive shorteningthe progressive shortening

    detected by serial sonar,detected by serial sonar,funneling (width and length),funneling (width and length),v-shaped lower uterine segmentv-shaped lower uterine segment

    and dynamic cervical changesand dynamic cervical changeswith fundal or suprapubicwith fundal or suprapubicpressure.pressure.

    What are the most

    important?

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    1 2

    3 4

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    bulging of the membranes in the vagina. The

    fetal lower limb protruded into the vagina.

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    But how to avoidBut how to avoidundue cerclageundue cerclage

    andand

    how not to miss ahow not to miss acase?case?

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    RISK ASSESMENT>=3 unexplained

    second-trimester losses

    or preterm deliveries.

    Elective Cerclage

    at 14-16 wk.

    No riskfactor

    routine ultrasound

    screening of the

    cervix is not

    recommended

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    Can a cervicalCan a cervical

    cerclage be used tocerclage be used to

    prevent pretermprevent pretermdelivery in patientsdelivery in patients

    with a short cervix orwith a short cervix orfunneling?funneling?

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    263116Obstetricianuncertainty

    12921993MRC/RCOG

    6.75.5

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    results of randomizedresults of randomized

    clinical trials suggest thatclinical trials suggest that

    cerclage either had acerclage either had a

    modest effect on reducingmodest effect on reducing

    the rate of preterm deliverythe rate of preterm deliveryor no effect whatsoeveror no effect whatsoever..

    RANDOMIZED STUDIES OFELECTIVE CERVICAL CERCLAGE

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    Key pointsKey pointsThe high negative predictiveThe high negative predictive

    value for preterm birthvalue for preterm birth

    associated with a long cervixassociated with a long cervixand with the absence ofand with the absence of

    funneling has important clinicalfunneling has important clinicalimplications in symptomaticimplications in symptomatic

    patients.patients.

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    Using TVU to assess CL is anUsing TVU to assess CL is an

    effective way to predict PTB andeffective way to predict PTB and

    "incompetent cervix," now better"incompetent cervix," now betternamed cervical insufficiency. It'snamed cervical insufficiency. It's

    safe and patients accept thesafe and patients accept theexamination well.examination well.

    Key pointsKey points

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    Screening frequency shouldScreening frequency should

    depend on severity of obstetricdepend on severity of obstetric

    history, with serial TVU of thehistory, with serial TVU of thecervix having a better predictivecervix having a better predictive

    accuracy than one, especially inaccuracy than one, especially inhigh-risk populations.high-risk populations.

    Key pointsKey points

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    screening high-risk women withscreening high-risk women with

    TVU of the cervix and placementTVU of the cervix and placement

    of a cerclage for the short orof a cerclage for the short orfunneled cervix should not befunneled cervix should not be

    considered standard care untilconsidered standard care until

    proven by properly conducted,proven by properly conducted,large randomized trialslarge randomized trials

    Key pointsKey points

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    ThankThankyouyou