ceva poultry vaccinology summit: barcelona , spain … · hydropericardium disease (hps)/angara...

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YG - 150910 New Trends in Poultry and Disease Spreading Risk Nick Dorko, DVM, MAM, ACPV Global Head of Veterinary Technical Services- Aviagen Ceva Poultry Vaccinology Summit: Barcelona , Spain March 15, 2016

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Page 1: Ceva Poultry Vaccinology Summit: Barcelona , Spain … · Hydropericardium Disease (HPS)/Angara Disease much more ... Clean House Syndrome Chicken Astrovirus ... broiler breeders

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New Trends in Poultry and Disease Spreading Risk

Nick Dorko, DVM, MAM, ACPVGlobal Head of Veterinary Technical Services- Aviagen

Ceva Poultry Vaccinology Summit: Barcelona , SpainMarch 15, 2016

Page 2: Ceva Poultry Vaccinology Summit: Barcelona , Spain … · Hydropericardium Disease (HPS)/Angara Disease much more ... Clean House Syndrome Chicken Astrovirus ... broiler breeders

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Lots of new trends (and some not so new) which can affect how we try to control disease To discuss several of these Try to give you some things to think

about From a production and disease control

perspective

Page 3: Ceva Poultry Vaccinology Summit: Barcelona , Spain … · Hydropericardium Disease (HPS)/Angara Disease much more ... Clean House Syndrome Chicken Astrovirus ... broiler breeders

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To Cover Variability The Market (Bird Sizes, etc.) Housing and Practices The Double D’s

Density and Downtime Antibiotic Free (ABF)

Page 4: Ceva Poultry Vaccinology Summit: Barcelona , Spain … · Hydropericardium Disease (HPS)/Angara Disease much more ... Clean House Syndrome Chicken Astrovirus ... broiler breeders

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Disclaimer I am not necessarily for or against

anything I am going to talk about There are positives and negatives to most

things We do many things for economic reasons

and not for what is necessarily best for the chicken

All things can be made to work Syndromes!!!

Page 5: Ceva Poultry Vaccinology Summit: Barcelona , Spain … · Hydropericardium Disease (HPS)/Angara Disease much more ... Clean House Syndrome Chicken Astrovirus ... broiler breeders

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Variability If you can control variability (or

reduce it), you will have better control of problems For example:

• Vaccination Crews versus growers or farm crews which do the vaccinating

• Consistency and expertise versus biosecurity and cost

Page 6: Ceva Poultry Vaccinology Summit: Barcelona , Spain … · Hydropericardium Disease (HPS)/Angara Disease much more ... Clean House Syndrome Chicken Astrovirus ... broiler breeders

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Vaccinations Hatchery

Reason why we now try to do as many vaccinations in the hatchery as we can

We have better control of the process Eyedrop versus DW or Spray

Less variability and higher accuracy More labor and potentially bird stress

(handling)

Page 7: Ceva Poultry Vaccinology Summit: Barcelona , Spain … · Hydropericardium Disease (HPS)/Angara Disease much more ... Clean House Syndrome Chicken Astrovirus ... broiler breeders

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Broiler Breeders Uniformity!!!

Light stimulation timing Birds over or underweight EODES (Erratic Oviposition and

Defective Egg Syndrome) Egg Yolk Peritonitis (EYP)

• Bird Management!!- Metabolic

Page 8: Ceva Poultry Vaccinology Summit: Barcelona , Spain … · Hydropericardium Disease (HPS)/Angara Disease much more ... Clean House Syndrome Chicken Astrovirus ... broiler breeders

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Housing and Equipment New Complexes = New Houses

Generally all houses same size and same equipment• Easier to set up programs

Usually much easier to manage because less variability house to house

Page 9: Ceva Poultry Vaccinology Summit: Barcelona , Spain … · Hydropericardium Disease (HPS)/Angara Disease much more ... Clean House Syndrome Chicken Astrovirus ... broiler breeders

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The Market Referring to:

Bird Size marketed at that complex or area

Special or New Marketing Trends in the area

Page 10: Ceva Poultry Vaccinology Summit: Barcelona , Spain … · Hydropericardium Disease (HPS)/Angara Disease much more ... Clean House Syndrome Chicken Astrovirus ... broiler breeders

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White Meat Markets Some growing areas prefer Breast

meat USA/Canada/Australia/New

Zealand/Parts of EU High breast meat yield breeders can

often be more difficult to manage Broilers often grown to heavier

weights

Page 11: Ceva Poultry Vaccinology Summit: Barcelona , Spain … · Hydropericardium Disease (HPS)/Angara Disease much more ... Clean House Syndrome Chicken Astrovirus ... broiler breeders

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Broiler Size In many areas broiler size (BWs at

kill) are increasing (i.e. USA)

Page 12: Ceva Poultry Vaccinology Summit: Barcelona , Spain … · Hydropericardium Disease (HPS)/Angara Disease much more ... Clean House Syndrome Chicken Astrovirus ... broiler breeders

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USA Broiler Weight Trends

Page 13: Ceva Poultry Vaccinology Summit: Barcelona , Spain … · Hydropericardium Disease (HPS)/Angara Disease much more ... Clean House Syndrome Chicken Astrovirus ... broiler breeders

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Broiler Size This can mean:

Longer time in the field (house) More time to be exposed to diseases or

poor management conditions Protection from vaccine (if vaccinated)

must be longer• Or extra vaccine given

Page 14: Ceva Poultry Vaccinology Summit: Barcelona , Spain … · Hydropericardium Disease (HPS)/Angara Disease much more ... Clean House Syndrome Chicken Astrovirus ... broiler breeders

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Thinning Practice where you go in multiple

times in a broiler flock to select out birds at certain target weights Common in many areas of Europe (EU),

Australia, New Zealand and elsewhere

Page 15: Ceva Poultry Vaccinology Summit: Barcelona , Spain … · Hydropericardium Disease (HPS)/Angara Disease much more ... Clean House Syndrome Chicken Astrovirus ... broiler breeders

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Thinning- Why? Often where growing areas are not

big enough to allow multiple complexes or processing plants

Also where housing and growing costs can be high

Allows you to put higher densities into your houses

Page 16: Ceva Poultry Vaccinology Summit: Barcelona , Spain … · Hydropericardium Disease (HPS)/Angara Disease much more ... Clean House Syndrome Chicken Astrovirus ... broiler breeders

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Thinning- Issues Multiple chances to introduce disease or

disease agents Increased growth spurt and potential

stress after each bird removal Excessive wing flapping and/or stress of

thinning process Green Muscle Disease

Page 17: Ceva Poultry Vaccinology Summit: Barcelona , Spain … · Hydropericardium Disease (HPS)/Angara Disease much more ... Clean House Syndrome Chicken Astrovirus ... broiler breeders

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Thinning United Kingdom banning because

linked to a higher level of colonization of the birds by Campylobacter

Page 18: Ceva Poultry Vaccinology Summit: Barcelona , Spain … · Hydropericardium Disease (HPS)/Angara Disease much more ... Clean House Syndrome Chicken Astrovirus ... broiler breeders

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Other Growing Trends Backyard Chickens Free Range Chickens Both are potential disease threats to

commercial poultry MG/MS, Avian Influenza, NDV, etc.

Page 19: Ceva Poultry Vaccinology Summit: Barcelona , Spain … · Hydropericardium Disease (HPS)/Angara Disease much more ... Clean House Syndrome Chicken Astrovirus ... broiler breeders

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Google MapsHowell FarmGP BreedersPulaski, TN

Page 20: Ceva Poultry Vaccinology Summit: Barcelona , Spain … · Hydropericardium Disease (HPS)/Angara Disease much more ... Clean House Syndrome Chicken Astrovirus ... broiler breeders

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Housing and Practices

Page 21: Ceva Poultry Vaccinology Summit: Barcelona , Spain … · Hydropericardium Disease (HPS)/Angara Disease much more ... Clean House Syndrome Chicken Astrovirus ... broiler breeders

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Multi-Age Farms We know this is not ideal but still

being done Land availability Costs (land, taxes, etc.) Often easier to manage

• All facilities in one place Still very common for commercial layers

• But new broiler breeder farms in some areas

Page 22: Ceva Poultry Vaccinology Summit: Barcelona , Spain … · Hydropericardium Disease (HPS)/Angara Disease much more ... Clean House Syndrome Chicken Astrovirus ... broiler breeders

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Multi-Age Farms

Harder to control disease Especially MG/MS, Salmonella, AI, NDV Vaccination Timing and Reactions

• Especially difficult for respiratory disease control and timing of live respiratory vaccinations

Page 23: Ceva Poultry Vaccinology Summit: Barcelona , Spain … · Hydropericardium Disease (HPS)/Angara Disease much more ... Clean House Syndrome Chicken Astrovirus ... broiler breeders

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Re- Using Litter Practice becoming more common in

some areas Common practice in USA, Brazil and

other Latin American countries USA also common in grow/pullet houses

for broiler breeders Broiler houses common to only do a

total cleanout once a year

Page 24: Ceva Poultry Vaccinology Summit: Barcelona , Spain … · Hydropericardium Disease (HPS)/Angara Disease much more ... Clean House Syndrome Chicken Astrovirus ... broiler breeders

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Re-Using Litter- Why? Cost and time for cleaning and

disinfection high Litter availability (and cost) How to get rid of the used litter and

where? Some countries easy to sell Some countries or areas hard to get rid

of because of environmental issues

Page 25: Ceva Poultry Vaccinology Summit: Barcelona , Spain … · Hydropericardium Disease (HPS)/Angara Disease much more ... Clean House Syndrome Chicken Astrovirus ... broiler breeders

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Re-Using Litter- Positives Cost

Including more cycles/year Seeding down the house with good

bacterial organisms (Probiotic effect) If vaccinating for coccidia, seeding

down house with vaccine strains

Page 26: Ceva Poultry Vaccinology Summit: Barcelona , Spain … · Hydropericardium Disease (HPS)/Angara Disease much more ... Clean House Syndrome Chicken Astrovirus ... broiler breeders

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Re-Using Litter-Challenges Must ventilate better to control ammonia and possible

respiratory issues, including vaccine reactions In areas of high AI and VVND challenge is difficult (or

impossible to do) Used litter spread near farms with birds can be a

source of infection Disease Issues?

Reovirus/ILT/Marek’s Disease(MDV)• Variant viruses/Mutations?

Page 27: Ceva Poultry Vaccinology Summit: Barcelona , Spain … · Hydropericardium Disease (HPS)/Angara Disease much more ... Clean House Syndrome Chicken Astrovirus ... broiler breeders

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“Clean House Syndrome” Cleaning and disinfection of farms is getting

better then ever Especially for control of Salmonella

More concrete floor houses USA and Brazil two places with not many concrete

floor houses As we do better C&D (especially formalin),

chickens are not getting naturally exposed to certain disease agents as they did in the past Birds with negative serology exposed during lay!!

Page 28: Ceva Poultry Vaccinology Summit: Barcelona , Spain … · Hydropericardium Disease (HPS)/Angara Disease much more ... Clean House Syndrome Chicken Astrovirus ... broiler breeders

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“Clean House Syndrome” Adenoviruses

Inclusion Body Hepatitis (IBH) and Hydropericardium Disease (HPS)/Angara Disease much more common

Where high challenge might have to vaccinate

Very few commercial vaccines available

Page 29: Ceva Poultry Vaccinology Summit: Barcelona , Spain … · Hydropericardium Disease (HPS)/Angara Disease much more ... Clean House Syndrome Chicken Astrovirus ... broiler breeders

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Clean House Syndrome Chicken Anemia Virus (CAV)

Breeders need to be positive before egg production

Many still rely on natural seroconversion Not such a reliable method

Page 30: Ceva Poultry Vaccinology Summit: Barcelona , Spain … · Hydropericardium Disease (HPS)/Angara Disease much more ... Clean House Syndrome Chicken Astrovirus ... broiler breeders

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Clean House Syndrome CAV

In my opinion all breeders should be vaccinated• If not monitor serology carefully and allow

time to vaccinate before production if needed

Too much we don’t know about CAV immunosuppression

Page 31: Ceva Poultry Vaccinology Summit: Barcelona , Spain … · Hydropericardium Disease (HPS)/Angara Disease much more ... Clean House Syndrome Chicken Astrovirus ... broiler breeders

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Table of CAV positive antibody (%)

Page 32: Ceva Poultry Vaccinology Summit: Barcelona , Spain … · Hydropericardium Disease (HPS)/Angara Disease much more ... Clean House Syndrome Chicken Astrovirus ... broiler breeders

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Clean House Syndrome Chicken Astrovirus (CAstV)?

“White Chick Syndrome” Are birds not getting naturally

exposed as they did in the past?

Other important agents might emerge in the future

Page 33: Ceva Poultry Vaccinology Summit: Barcelona , Spain … · Hydropericardium Disease (HPS)/Angara Disease much more ... Clean House Syndrome Chicken Astrovirus ... broiler breeders

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Density and Downtime

Page 34: Ceva Poultry Vaccinology Summit: Barcelona , Spain … · Hydropericardium Disease (HPS)/Angara Disease much more ... Clean House Syndrome Chicken Astrovirus ... broiler breeders

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High Density Poultry Areas In high density poultry areas disease challenge is

usually much higher Strict biosecurity procedures Different vaccination programs (more intense) are

often required In very high poultry population areas it can be difficult

to control diseases, especially in breeders Often have to move breeders to a different area

• DMV in the USA• Subang area in Indonesia• Luzon area in Philippines

Page 35: Ceva Poultry Vaccinology Summit: Barcelona , Spain … · Hydropericardium Disease (HPS)/Angara Disease much more ... Clean House Syndrome Chicken Astrovirus ... broiler breeders

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Density in the House Trend is to increase bird density, especially in

broiler breeders to try to maximize space and profit

You can increase density up to a certain point This must be determined with trials Can vary depending on

• House style• Ventilation systems

• Equipment, especially feeding equipment• Time of the year

• Winter versus Summer• Welfare Regulations

Page 36: Ceva Poultry Vaccinology Summit: Barcelona , Spain … · Hydropericardium Disease (HPS)/Angara Disease much more ... Clean House Syndrome Chicken Astrovirus ... broiler breeders

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Density- More Meat!!!

Page 37: Ceva Poultry Vaccinology Summit: Barcelona , Spain … · Hydropericardium Disease (HPS)/Angara Disease much more ... Clean House Syndrome Chicken Astrovirus ... broiler breeders

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Density-Can have effects on FCR and Feathering

Page 38: Ceva Poultry Vaccinology Summit: Barcelona , Spain … · Hydropericardium Disease (HPS)/Angara Disease much more ... Clean House Syndrome Chicken Astrovirus ... broiler breeders

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Density- Effects on Mortality and Growth Rate

Page 39: Ceva Poultry Vaccinology Summit: Barcelona , Spain … · Hydropericardium Disease (HPS)/Angara Disease much more ... Clean House Syndrome Chicken Astrovirus ... broiler breeders

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Consequences of Too High Density Decreased feed

consumption Decreased growth rate Decreased feed efficiency Increased mortality Increase cannabilism Increase breast blisters

and paw damage

Increase in birds with poor feathering

Increased condemnations Increased house

ventilation requirement Increase in kgs of broilers

raised in a house during a 12 month period

Page 40: Ceva Poultry Vaccinology Summit: Barcelona , Spain … · Hydropericardium Disease (HPS)/Angara Disease much more ... Clean House Syndrome Chicken Astrovirus ... broiler breeders

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Density- Potential outcomes Breeders- Feed Space!!!

Performance effects• Less eggs• More floor eggs• Staph/Leg Issues

Increased mortality• Cannabilism• EYP

Page 41: Ceva Poultry Vaccinology Summit: Barcelona , Spain … · Hydropericardium Disease (HPS)/Angara Disease much more ... Clean House Syndrome Chicken Astrovirus ... broiler breeders

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Higher the Density Disease control can often become

more difficult Change in vaccination ?

Mortality and condemnations can become increased

Performance can be decreased Must fine tune what is the best bird

density for your situation

Page 42: Ceva Poultry Vaccinology Summit: Barcelona , Spain … · Hydropericardium Disease (HPS)/Angara Disease much more ... Clean House Syndrome Chicken Astrovirus ... broiler breeders

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Downtime/Turnaround Time Definition-The time that the last

chickens leave the farm (go to market) until the next (first) chicks arrive

Many Factors Can Complicate This!!! Multi-Age? Re-Used Litter? Previous Disease Outbreak?

Page 43: Ceva Poultry Vaccinology Summit: Barcelona , Spain … · Hydropericardium Disease (HPS)/Angara Disease much more ... Clean House Syndrome Chicken Astrovirus ... broiler breeders

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“ The Downtime Syndrome” Breed doesn’t change Vaccination doesn’t change Feed doesn’t change But the customer complains:

FCR increase 2-5 points Growth rate slow Uniformity not good Often RSS(Runting/Stunting Syndrome)

Page 44: Ceva Poultry Vaccinology Summit: Barcelona , Spain … · Hydropericardium Disease (HPS)/Angara Disease much more ... Clean House Syndrome Chicken Astrovirus ... broiler breeders

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“ The Downtime Syndrome” What changed?

Shortened Downtime!!! Usually less then 10 days for MORE

then 1 cycle• Especially more then two cycles

Worse on multi-age facilities • Younger aged birds usually worse affected

Page 45: Ceva Poultry Vaccinology Summit: Barcelona , Spain … · Hydropericardium Disease (HPS)/Angara Disease much more ... Clean House Syndrome Chicken Astrovirus ... broiler breeders

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Effects of Downtime in a Large Poultry Integration

Page 46: Ceva Poultry Vaccinology Summit: Barcelona , Spain … · Hydropericardium Disease (HPS)/Angara Disease much more ... Clean House Syndrome Chicken Astrovirus ... broiler breeders

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Average Daily Gain by Down Time Total

0.096

0.098

0.100

0.102

0.104

0.106

0.108

0.110

1 to 7 8 to 14 15 to 21 Over 21

Total

YearSold(All) YEARMO(All) MaleBre(All) FemBre (All) BREEDC(All) FLOCKT(All) WtRang(All) FARMN (All) TUNNEL(All) HatSour(All) GrowerR(All) TA (All)

Average of GainDay

DowntimeCat

Présentateur
Commentaires de présentation
As downtime increases, so does average daily gain. This graph depicts all years.
Page 47: Ceva Poultry Vaccinology Summit: Barcelona , Spain … · Hydropericardium Disease (HPS)/Angara Disease much more ... Clean House Syndrome Chicken Astrovirus ... broiler breeders

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Average Adj. FCR by Down Time Total

1.600

1.650

1.700

1.750

1.800

1.850

1.900

1.950

2.000

1 to 7 8 to 14 15 to 21 Over 21

Total

YearSold(All) YEARMO(All) MaleBre(All) FemBre (All) BREEDC(All) FLOCKT(All) WtRang(All) FARMN (All) TUNNEL(All) HatSour(All) GrowerR(All) TA (All)

Average of AdjFCRto5at10

DowntimeCat

Présentateur
Commentaires de présentation
As down time increase, FCR decrease. All years represented.
Page 48: Ceva Poultry Vaccinology Summit: Barcelona , Spain … · Hydropericardium Disease (HPS)/Angara Disease much more ... Clean House Syndrome Chicken Astrovirus ... broiler breeders

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Average Livability by Down Time Total

80.00

82.00

84.00

86.00

88.00

90.00

92.00

94.00

96.00

98.00

1 to 7 8 to 14 15 to 21 Over 21

Total

YearSold(All) YEARMO(All) MaleBre(All) FemBre (All) BREEDC(All) FLOCKT(All) WtRang(All) FARMN (All) TUNNEL(All) HatSour(All) GrowerR(All) TA (All)

Average of Livability

DowntimeCat

Présentateur
Commentaires de présentation
As down time increases, so does livability. This graph depicts all years.
Page 49: Ceva Poultry Vaccinology Summit: Barcelona , Spain … · Hydropericardium Disease (HPS)/Angara Disease much more ... Clean House Syndrome Chicken Astrovirus ... broiler breeders

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“The Downtime Syndrome” What is probably happening?

Build-up of pathogens• Viruses??

Improper C&D• Not enough time to properly do or not done

at all

Page 50: Ceva Poultry Vaccinology Summit: Barcelona , Spain … · Hydropericardium Disease (HPS)/Angara Disease much more ... Clean House Syndrome Chicken Astrovirus ... broiler breeders

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Antibiotic Free (ABF) An increasing trend, especially in

USA, Canada and parts of the EU Currently in the USA about 42%

broilers are grown on some type of ABF program Around 13% on NAE (includes no

ionophores)

Page 51: Ceva Poultry Vaccinology Summit: Barcelona , Spain … · Hydropericardium Disease (HPS)/Angara Disease much more ... Clean House Syndrome Chicken Astrovirus ... broiler breeders

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Antibiotic Free (ABF)

What are the main problems on ABF: Higher first week mortality

• Omphalitis/”Yolksacculitis” Necrotic Enteritis Bacterial Chondronecrosis and Osteomyelitis

(BCO, formerly known as FHN) Vertebral Osteoarthritis (VOA)

Page 52: Ceva Poultry Vaccinology Summit: Barcelona , Spain … · Hydropericardium Disease (HPS)/Angara Disease much more ... Clean House Syndrome Chicken Astrovirus ... broiler breeders

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Summary Practices in the poultry industry are

constantly changing around the globe

Broilers are being marketed at higher body weights and with more yield This means a longer time in the field

where they can be exposed to disease challenges

Page 53: Ceva Poultry Vaccinology Summit: Barcelona , Spain … · Hydropericardium Disease (HPS)/Angara Disease much more ... Clean House Syndrome Chicken Astrovirus ... broiler breeders

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Summary More birds in a house, whether

broilers or breeders, can create very different challenges in growing practices

Shortened downtimes can lead to decreased performance and increased disease problems

Page 54: Ceva Poultry Vaccinology Summit: Barcelona , Spain … · Hydropericardium Disease (HPS)/Angara Disease much more ... Clean House Syndrome Chicken Astrovirus ... broiler breeders

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Summary ABF programs which are increasing

in popularity in some areas offer new challenges especially with bacterial infections

Good biosecurity and health programs (including vaccinations) can help to reduce issues in the areas discussed in this talk

Page 55: Ceva Poultry Vaccinology Summit: Barcelona , Spain … · Hydropericardium Disease (HPS)/Angara Disease much more ... Clean House Syndrome Chicken Astrovirus ... broiler breeders

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Thank You! Questions?