Challenge and Innovation in CardiovascularTherapeutics: 1st Annual BHF Centre Symposium

Michael D. Schneider MD FMedSciHead, National Heart and Lung Institute, Imperial College LondonDirector, British Heart Foundation Centre for Research ExcellenceSimon Marks BHF Chair in Regenerative Cardiologywww.imperial.ac.uk/bhfcre

Challenge and Innovation in CardiovascularTherapeutics: 1st Annual BHF Centre Symposium

Michael D. Schneider MD FMedSciHead, National Heart and Lung Institute, Imperial College LondonDirector, British Heart Foundation Centre for Research ExcellenceSimon Marks BHF Chair in Regenerative Cardiologywww.imperial.ac.uk/bhfcre

BHF Centre for Research Excellence at ImperialBHF Centre for Research Excellence at Imperial

BHF Centre - Research TeamsBHF Centre - Research Teams

Biomedical Sciences

Stem Cell & Developmental Biology

Regenerative Medicine & Tissue Engineering

Vascular Biology, Thrombosis & Inflammation

Pulmonary Vascular Disease: Bench to Bedside and Back

Electrophysiology & Membrane Biophysics

Signal Transduction & Gene Expression

Biology of the Failing Heart

Cardiac Imaging

Applied Physiology & Bioengineering: Clinical Implementation

Cardiovascular Epidemiology & Clinical Trials

Genetics, Genomics, & Physiology

Physical and Computational Sciences

Physiological & Pathological Fluid-Tissue Interactions

Arterial Pulse Wave Analysis for Clinical Diagnosis

Robotics & Minimially Invasive Surgery

Bioprocessing & Biomechanics for Tissue Engineering

Chemical Biology: Protein-Protein & Protein-Lipid Interactions

Chemical Biology: Single-cell Proteomics

Chemical Biology: Chemical Genetics

Multi-scale Modeling of Bio-systems

Systems Biology

11 Life Science teams x 9 Physical Science teams = 99 pairwise combinations

Components of Imperial’s BHF CentreComponents of Imperial’s BHF Centre

• New four-year MRes / PhD programme, bespoke curriculum, cross-disciplinary design, dual mentoring

• Physician-scientist support• 7 flagship postdoctoral projects in the Directors’ labs• Pump-priming pilot project support • Core support posts for animal microsurgery & bioinformatics• Core facilities for transgenesis, knockouts• Visiting professors — Jason Yuan (‘08), Eric Olson (‘09)• Seminar series, specialized workshops

– Advanced Optical Methods in Cardiovascular Research• BHF Centre as a platform to other funding (e.g. RBHT BRU)• Annual Symposium

• New four-year MRes / PhD programme, bespoke curriculum, cross-disciplinary design, dual mentoring

• Physician-scientist support• 7 flagship postdoctoral projects in the Directors’ labs• Pump-priming pilot project support • Core support posts for animal microsurgery & bioinformatics• Core facilities for transgenesis, knockouts• Visiting professors — Jason Yuan (‘08), Eric Olson (‘09)• Seminar series, specialized workshops

– Advanced Optical Methods in Cardiovascular Research• BHF Centre as a platform to other funding (e.g. RBHT BRU)• Annual Symposium

A vigorous recruitment programmeA vigorous recruitment programme

• Chair in Developmental Dynamics (offered)

• Chair in Cardiovascular Genetics (offered)

• Chair in Cardiovascular Genomics and Systems Biology

• Chair in Cardiac Surgery

• Chair in Cardiovascular Stem Cell Biology and Regenerative Medicine

• Lecturer in Vascular Inflammation

• Clinical trialists in heart failure and acute ischemic injury

• Many other posts, awaiting new space…

• Chair in Developmental Dynamics (offered)

• Chair in Cardiovascular Genetics (offered)

• Chair in Cardiovascular Genomics and Systems Biology

• Chair in Cardiac Surgery

• Chair in Cardiovascular Stem Cell Biology and Regenerative Medicine

• Lecturer in Vascular Inflammation

• Clinical trialists in heart failure and acute ischemic injury

• Many other posts, awaiting new space…

Hammersmith campus developmentHammersmith campus development

• New L Block (£99M), due Xmas 2011 • 3 cardiovascular floors, 60,000 sq ft, 250-300 researchers• Adjacent to MRC CSC and WT Clinical Research Facility• Large-mammal cath lab (BHF) & imaging suite, April 2010

• New L Block (£99M), due Xmas 2011 • 3 cardiovascular floors, 60,000 sq ft, 250-300 researchers• Adjacent to MRC CSC and WT Clinical Research Facility• Large-mammal cath lab (BHF) & imaging suite, April 2010

A few housekeeping detailsA few housekeeping details