chapter 7 chapter 7 the muscular system. function of muscles produce movement maintain posture ...
TRANSCRIPT
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Chapter 7Chapter 7The Muscular System
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Function of MusclesFunction of Muscles
Produce movement Maintain posture Stabilize joints Generate heat Guards openings
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Fun Facts about MusclesFun Facts about Muscles
• There are 656 muscles in the human body.
• It takes 17 muscles to smile and 43 to frown.
• The tongue is the strongest muscle in the body.
• The gluteus maximus (the buttocks) is the largest muscle in the body.
• The sartorius muscle is the longest muscle in the body.
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The Muscular SystemThe Muscular SystemThree types of muscle tissue :
Skeletal1) Attach to the bony skeleton2) Have longest fibers, fibers are striated (striped)3) Controlled voluntarily
Smooth1) Linings of organs and cavities2) Fibers are non-striated3) Controlled involuntarily, function constantly
Cardiac1) Found only in the heart2) Fibers are striated3) Controlled involuntarily
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Smooth Muscle CharacteristicsSmooth Muscle Characteristics
Has no striations
Single nucleus
Found mainly in the walls of hollow organs
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Smooth MuscleSmooth Muscle
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Cardiac Muscle CharacteristicsCardiac Muscle Characteristics
Has striations
Usually has a single nucleus
Joined to another muscle cell at an intercalated disc Found only in the heart
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Cardiac MuscleCardiac Muscle
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Functional Characteristics of Functional Characteristics of MusclesMuscles Four properties of muscle:
1)Excitability: ability to receive and respond to a stimulus
2)Contractility: ability to shorten with force when stimulated
3)Extensibility: ability to be stretched or extended
4)Elasticity: ability of a muscle fiber to return to its original or resting length
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SkeletalSkeletal Muscle Organization Muscle Organization
Muscle fascicle (bundle)
Muscle fiber (cell)
Myofibril
Sarcomere (Contractile unit of muscle fiber)
Thick and thin filaments
Skeletal Muscle
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Anatomy of a Skeletal Muscle Anatomy of a Skeletal Muscle
• Consists of many bundles, called fascicles, of fibers covered by
connective tissue
• Each muscle contains at least one artery and one or two veins
… why?
• Most attach to bones by tendons (connective tissue extensions)
1) insertion: bone that moves during contraction
2) origin: bone that stays still during contraction
• Some muscles attach directly to bone by their connective
tissue coverings
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Connective Tissue Wrappings Connective Tissue Wrappings ofofSkeletal MuscleSkeletal Muscle Epimysium –
covers skeletal muscle
Perimysium – covers fascicle (bundle) of fibers
Endomysium – around single muscle fiber
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Microscopic Anatomy of a Microscopic Anatomy of a Skeletal Muscle Skeletal Muscle • Muscle fiber: muscle cell with many nuclei
• Sarcolemma: plasma membrane of a muscle cell
• Sarcoplasm: cytoplasm of muscle cell, contains large amounts of glycogen and oxygen-binding protein
• Each muscle fiber contains large numbers of myofibrils in the sarcoplasm, with mitochondria packed around them
• Myofibrils: contractile portion of the muscle cell, made up of units called sarcomeres
• Sarcomeres contain two types of filaments:
1) thick: contain the protein myosin
2) thin: contain the protein actin
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Microscopic Anatomy of the MuscleMicroscopic Anatomy of the Muscle
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At rest, there is a bare zone that lacks actin filaments (no filament overlap)
Muscle Contraction: Sliding Filament TheoryMuscle Contraction: Sliding Filament Theory
To start contraction, calcium unlocks active sites on actin
Myosin heads bind to actin active sites – connections are called cross-bridges
Myosin pulls the actin microfilaments toward the bare zone - muscle shortens
Myosin detaches, then reattaches to another active site, shortening the muscle further
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Muscle Contraction: Sliding Filament Muscle Contraction: Sliding Filament TheoryTheory
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Sliding Filament Animation
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Muscle Contraction: Rigor MortisMuscle Contraction: Rigor Mortis• After death, there is an influx of calcium
• Calcium causes myosin to bind with actin (forming cross bridges)
• Breathing stops, no energy is available to detach cross bridges, so they stay attached
• Muscles stiffen after 3 to 4 hours, peaks at 12 hours, and decreases between 48 and 60 hours
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Nerve Stimulus for Muscle Nerve Stimulus for Muscle ContractionContraction Skeletal muscles must be stimulated by a motor neuron (nerve) to contract
Motor neuron plus the fibers it supplies is called the “motor unit”
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Neuromuscular junctions (NMJ) – site where nerve and muscle meet
Nerve Stimulus for Muscle Nerve Stimulus for Muscle ContractionContraction
Nerve and muscle do not make direct contact
Synaptic cleft – gap between nerve and muscle fiber, filled with fluid
Each muscle fiber has only one neuromuscular junction
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Nerve Stimulus for Muscle Contraction:Nerve Stimulus for Muscle Contraction:Neuromuscular JunctionNeuromuscular Junction
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Nerve Stimulus for Muscle Nerve Stimulus for Muscle ContractionContraction
Upon arrival of nerve impulse, a chemical called a neurotransmitter is released by nerve The neurotransmitter for skeletal muscle is
acetylcholine Neurotransmitter attaches to receptors on the sarcolemma of the muscle fiber
Brain or spinal cord sends a nerve impulse down the motor neuron in response to a stimulus
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Nerve Stimulus for Muscle Nerve Stimulus for Muscle ContractionContraction Sarcolemma becomes permeable to sodium
ions (Na+)
Sodium rushes into the cell and generates an action potential - an explosion of electrical activity
This electrical stimulus starts the muscle contraction
Once the contraction starts, it cannot be stopped - ALL OR NOTHING PRINCIPLE
Neuromuscular Junction Animation
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Contraction of a Skeletal MuscleContraction of a Skeletal Muscle Within a skeletal muscle, not all fibers may
be stimulated at the same time
Different combinations of muscle fiber contractions may give differing responses
Graded responses – different degrees of skeletal muscle contraction
Example: finger muscles help you pick up a penny or a textbook
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Muscle ToneMuscle Tone Slightly contracted state while
muscle is at rest
Keeps muscles ready to respond to stimulation
Helps maintain posture
Stabilizes your joints
Atrophy – decrease in muscle tone; fibers become small and weak without stimulation
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a. Twitch – single, jerky contraction from a single stimulus
Not a normal contraction
b. Tetanus – smooth, sustained contraction from multiple stimuli building upon each other
Cannot go on indefinitely or results in fatigue
c. Treppe effect – increasingly forceful contractions due to increased efficiency of muscle, even with same stimulus
As muscle warms up, more calcium is available, and enzymes are more effective
Muscle Responses to StimuliMuscle Responses to Stimuli
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Types of Muscle ContractionsTypes of Muscle Contractions1) Isotonic contractions
Tension remains constant The muscle changes length so
movement can occur
a. Concentric – muscle shortens as it contracts
b. Eccentric – muscle lengthens as it contracts2) Isometric contractions
Tension in the muscles increases The muscle does not change length so positions can be held
**Most body movements are a combination of both types.**
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Force of Muscle ContractionForce of Muscle Contraction
Depends on four things:
1) # of muscle fibers contracting – greater the number of motor units contracting, the greater the force
2) Size of the muscle – bigger the muscle, the greater the force
3) Elastic elements (tendons, tissue coverings) – greater the tension on the elastic elements, the greater the force
4) Degree of muscle stretch – slight stretch increases the force of contraction
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ATP is the only energy source used for muscle contraction
Only 4-6 seconds worth of ATP is stored by muscles
After this initial time, other pathways must be utilized to produce ATP
a.Anaerobic glycolysis/lactic acid fermentation
b.Aerobic respiration
Energy for Muscle ContractionEnergy for Muscle Contraction
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Energy for Muscle ContractionEnergy for Muscle Contraction Anaerobic Glycolysis/Lactic Acid
Fermentation (NO OXYGEN AVAILABLE) Series of chemical reactions that makes ATP from glucose without oxygen
This reaction FAST, but inefficient Huge amounts of glucose are needed to make ATP
Lactic acid is a waste product of the reactions, causes muscle fatigue and soreness
Provides 90 seconds of energy – weightlifting, sprints
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Energy for Muscle ContractionEnergy for Muscle Contraction Aerobic Respiration
(OXYGEN IS AVAILABLE) Series of chemical reactions that makes
ATP from glucose in the presence of oxygen This is a slow reaction, but makes huge amounts of ATP
Breaks down glycogen (chains of glucose) stored in muscles and liver
Carbon dioxide and water are waste products of the reactions (breathing out and sweating)
Provides 15-20 minutes of energy – long distance running, endurance exercises
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Critical Thinking Question:Critical Thinking Question:
After 20 minutes of exercise, your body has used up all the stored glycogen. What do you use for energy after that? What does
this help with?
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Effects of Exercise on MuscleEffects of Exercise on MuscleResults of increased muscle use:
Increase in muscle size (size of fiber, not number of fibers increases)
Increase in muscle strength
Increase in muscle efficiency (more capillaries, more mitochondria)
Muscle becomes more fatigue resistant (more glycogen is stored, more mitochondria)
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Muscles and Body MovementsMuscles and Body Movements Movement is
attained due to a muscle moving an attached bone
Insertion – muscle attachment to bone that MOVES during contraction
Review:
Origin – muscle attachment on bone that DOES NOT MOVE during contraction
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Types of Body MovementsTypes of Body Movements
Review:
Flexion
Extension
Rotation
Abduction
Circumduction
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Types of Body MovementsTypes of Body Movements
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Producing Body Movements:Producing Body Movements:Skeletal Muscle InteractionsSkeletal Muscle Interactions
1) Prime Mover or Agonist: muscle(s) that provides the greatest force of a movement
2) Antagonist: muscle(s) that oppose or reverse a particular movement, to regulate or resist the agonist
3) Synergist: muscle that aids the agonist by:
a. Promoting the same movement
b. Reducing unnecessary movement by stabilizing or fixating a joint and/or bone
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Naming of Skeletal MusclesNaming of Skeletal Muscles
1) Location of the muscle
Example: temporalis (located on the temporal bone)
2) Number of origins
Example: triceps (three origins)
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Naming of Skeletal MusclesNaming of Skeletal Muscles
3) Direction of muscle fibers
Example: rectus abdominis (straight)
4) Relative size of the muscle
Example: gluteus maximus (largest)
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Naming of Skeletal MusclesNaming of Skeletal Muscles5) Location of the muscles origin and
insertion
Example: sternocleidomastoid (originates on the sternum and clavicle, inserts on the mastoid)
6) Shape of the muscle
Example: deltoid (triangular)
7) Action of the muscle
Example: extensor digitorum longus (extends the fingers)
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Head and Neck MusclesHead and Neck Muscles
Figure 6.14
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Superficial Trunk and Arm Superficial Trunk and Arm MusclesMuscles
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Deep Trunk and Arm MusclesDeep Trunk and Arm Muscles
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Muscles of the Anterior Pelvis, Hip, and Muscles of the Anterior Pelvis, Hip, and ThighThigh
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Muscles of the Posterior Pelvis, Hip, and Muscles of the Posterior Pelvis, Hip, and ThighThigh
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Superficial Muscles: AnteriorSuperficial Muscles: Anterior
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Superficial Muscles: PosteriorSuperficial Muscles: Posterior
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Muscular System DisordersMuscular System DisordersChronic Fatigue Syndrome
Fibromyalgia
Duchenne’s Muscular Dystrophy
Rotator Cuff Syndrome
Anterior Compartment Syndrome
Rhabdomyolysis
Cardiomyopathy
Myasthenia Gravis
Rhabdomyosarcoma
Inguinal Hernia
Polio
Carpal Tunnel Syndrome