chapter 8.2: the nervous system. neuroglia astrocytes largest and most numerous maintain...

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Chapter 8.2: The Nervous System

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Page 1: Chapter 8.2: The Nervous System. Neuroglia  Astrocytes  Largest and most numerous  Maintain blood-brain barrier  Isolates CNS from circulation  Capillaries

Chapter 8.2: The Nervous System

Page 2: Chapter 8.2: The Nervous System. Neuroglia  Astrocytes  Largest and most numerous  Maintain blood-brain barrier  Isolates CNS from circulation  Capillaries

Neuroglia

AstrocytesLargest and most numerousMaintain blood-brain barrier Isolates CNS from circulationCapillaries impermeableRepair damaged neural tissue

Page 3: Chapter 8.2: The Nervous System. Neuroglia  Astrocytes  Largest and most numerous  Maintain blood-brain barrier  Isolates CNS from circulation  Capillaries

Figure 8.4

Page 4: Chapter 8.2: The Nervous System. Neuroglia  Astrocytes  Largest and most numerous  Maintain blood-brain barrier  Isolates CNS from circulation  Capillaries

Neuroglia cont… Oligodendrocytes Coats axons with myelin Nodes of Ranvier Parts of axon with no myelin Internodes Parts of axon with myelin Myelin increases speed of action

potential

Page 5: Chapter 8.2: The Nervous System. Neuroglia  Astrocytes  Largest and most numerous  Maintain blood-brain barrier  Isolates CNS from circulation  Capillaries

Figure 8.5

Page 6: Chapter 8.2: The Nervous System. Neuroglia  Astrocytes  Largest and most numerous  Maintain blood-brain barrier  Isolates CNS from circulation  Capillaries

Neuroglia cont… Microglia Engulf wastes and pathogens

Page 7: Chapter 8.2: The Nervous System. Neuroglia  Astrocytes  Largest and most numerous  Maintain blood-brain barrier  Isolates CNS from circulation  Capillaries

Figure 8.4

Page 8: Chapter 8.2: The Nervous System. Neuroglia  Astrocytes  Largest and most numerous  Maintain blood-brain barrier  Isolates CNS from circulation  Capillaries

Neuroglia cont… Ependymal Cells Produces cerebrospinal fluid

Page 9: Chapter 8.2: The Nervous System. Neuroglia  Astrocytes  Largest and most numerous  Maintain blood-brain barrier  Isolates CNS from circulation  Capillaries

Figure 8.4

Page 10: Chapter 8.2: The Nervous System. Neuroglia  Astrocytes  Largest and most numerous  Maintain blood-brain barrier  Isolates CNS from circulation  Capillaries

Neuroglia cont… Satellite Cells Support cell bodies Schwann Cells Covers axons—called neurilemma

Page 11: Chapter 8.2: The Nervous System. Neuroglia  Astrocytes  Largest and most numerous  Maintain blood-brain barrier  Isolates CNS from circulation  Capillaries

Figure 8.5b

Page 12: Chapter 8.2: The Nervous System. Neuroglia  Astrocytes  Largest and most numerous  Maintain blood-brain barrier  Isolates CNS from circulation  Capillaries

Demyelination Disorders Demyelination Progressive destruction of myelin Inflammation Axon Damage Scarring of neural tissue Gradual loss of sensation and motor

control Numbness and paralysis

Page 13: Chapter 8.2: The Nervous System. Neuroglia  Astrocytes  Largest and most numerous  Maintain blood-brain barrier  Isolates CNS from circulation  Capillaries

Disorders cont… Multiple Sclerosis (MS) Optic nerve, brain and spinal cord

affected Partial loss of vision Problems with speech, balance and

motor coordination

Page 14: Chapter 8.2: The Nervous System. Neuroglia  Astrocytes  Largest and most numerous  Maintain blood-brain barrier  Isolates CNS from circulation  Capillaries
Page 15: Chapter 8.2: The Nervous System. Neuroglia  Astrocytes  Largest and most numerous  Maintain blood-brain barrier  Isolates CNS from circulation  Capillaries

Neuron Anatomy Neuron cell bodies—gray matter Located in ganglia of PNS White matter—bundles of axons Called nerves

Page 16: Chapter 8.2: The Nervous System. Neuroglia  Astrocytes  Largest and most numerous  Maintain blood-brain barrier  Isolates CNS from circulation  Capillaries

Figure 8.6

Page 17: Chapter 8.2: The Nervous System. Neuroglia  Astrocytes  Largest and most numerous  Maintain blood-brain barrier  Isolates CNS from circulation  Capillaries

Membrane Potential Polarized—resting cell membrane Resting Potential—membrane

potential of resting neuron -70mV More negative ions inside than out of

neuron

Page 18: Chapter 8.2: The Nervous System. Neuroglia  Astrocytes  Largest and most numerous  Maintain blood-brain barrier  Isolates CNS from circulation  Capillaries

Figure 8.8 5

Page 19: Chapter 8.2: The Nervous System. Neuroglia  Astrocytes  Largest and most numerous  Maintain blood-brain barrier  Isolates CNS from circulation  Capillaries

Potential cont… Depolarization Shift membrane potential towards

positive Ex: 0 mV

Page 20: Chapter 8.2: The Nervous System. Neuroglia  Astrocytes  Largest and most numerous  Maintain blood-brain barrier  Isolates CNS from circulation  Capillaries

Figure 8.8 5

Page 21: Chapter 8.2: The Nervous System. Neuroglia  Astrocytes  Largest and most numerous  Maintain blood-brain barrier  Isolates CNS from circulation  Capillaries

Potential Cont… Hyperpolarization Shift membrane potential towards

more negative Ex: - 80 mV

Page 22: Chapter 8.2: The Nervous System. Neuroglia  Astrocytes  Largest and most numerous  Maintain blood-brain barrier  Isolates CNS from circulation  Capillaries

Figure 8.8 5

Page 23: Chapter 8.2: The Nervous System. Neuroglia  Astrocytes  Largest and most numerous  Maintain blood-brain barrier  Isolates CNS from circulation  Capillaries

Potential cont… Action Potential Triggered by depolarization Membrane potential must reach

threshold -60 mV

Page 24: Chapter 8.2: The Nervous System. Neuroglia  Astrocytes  Largest and most numerous  Maintain blood-brain barrier  Isolates CNS from circulation  Capillaries

Figure 8.8 5

Page 25: Chapter 8.2: The Nervous System. Neuroglia  Astrocytes  Largest and most numerous  Maintain blood-brain barrier  Isolates CNS from circulation  Capillaries

Potential cont… Repolarization Return to resting potential

Page 26: Chapter 8.2: The Nervous System. Neuroglia  Astrocytes  Largest and most numerous  Maintain blood-brain barrier  Isolates CNS from circulation  Capillaries

Figure 8.8 5