charged aerosol detection...

Introduction Antibiotics Carbohydrates Food/Nutrition General Lipids Miscellaneous Natural Products/Supplements

Pharmaceutical Polymers/Surfactants

Proteins/Peptides

Charged Aerosol Detection Bibliography

Introduction

Since its introduction in 2005, charged aerosol detection

has become the preferred universal LC detector for

both routine and complex analyses. This bibliography

is designed to readily show the analytical capabilities of

charged aerosol detection and highlights the breadth

and scope of the different analytical methods found

in the literature.

For ease of use, the document is divided into different

categories based on either the family of analytes being

measured (e.g., carbohydrates, lipids, surfactants)

or the relevant market place (e.g., Food/Nutrition,

Pharmaceutical) being served. Each publication is

hyperlinked so that you can obtain more information

about the article including analytes being measured and

sample matrices.



Proteins/Peptides

No single liquid chromatography (LC) detector delivers

ideal results. Often, one analyte responds more strongly

than another, or may not respond at all. UV absorbance

detection requires that the molecule contain a chromo-

phore and Inter-analyte response can vary greatly

depending upon the nature of the chromophore present.

Refractive index detection cannot be used with gradient

elution and is temperature sensitive.

Mass spectrometry can only measure compounds that

will form gas-phase ions.

Evaporative light scattering detection shows varied inter-

analyte response and complex, non-linear calibration

curves.

What is most desired in a universal detector is the

ability to accurately measure a wide range of analytes

with consistent response. Charged aerosol detection

can measure any non-volatile and most semi-volatile

analytes at sub-nanogram levels and does not require

a compound to contain a chromophore or be able

to ionize. Variance in inter-analyte relative response

is minimal whether analyzing small molecules or

proteins. The technique is fully compatible with gradient

chromatography.

Introduction

Why Use Charged Aerosol Detection?



Proteins/Peptides

Charged aerosol detection first nebulizes eluent from

the column. Large droplets exit the detector to waste.

Selected smaller droplets enter the evaporation tube and

form particles once the solvent is evaporated. Particles

then enter a reaction chamber where they collide with

ionized gas formed when nitrogen is passed over a corona

wire. Charge is transferred from the ionized gas to the

analyte particles. Once unreacted ionized gas is removed

by an ion trap, the charge on the particle is measured by

a sensitive electrometer. The response of the detector

is directly related to the mass of the analyte entering the

detector. An increase in the amount of an analyte eluting

from the column leads to an increase in the size of the

particles being formed. Larger particles can accommodate

more charge, resulting in a higher response from the

detector. As long as the analyte will form a particle it will be

measured by charged aerosol detection, independent of

its chemical structure.

Charged aerosol detection delivers predictable results

without the need for complex detector optimization and

has the flexibility to measure a broad range of analytes in

many different matrices. The Thermo Scientific Dionex

Corona Veo charged aerosol detector is HPLC/UHPLC

compatible and with its extended flow rate range, can

be used with capillary, microbore, and analytical-scale

columns. The detector improves on all the benefits of

charged aerosol detection in a design perfectly matched to

your laboratorys needs.

How the Technology Works

Introduction



Proteins/Peptides

Antibiotics



Proteins/Peptides

Title Authors PublicationPublication Date

Production of surfactin and iturin by Bacillus licheniformis N1 responsible for plant disease control activity.

Gi Kong, H.; Kim, J.; Choi, G.; Lee, K.; Kim, H.; Hwang, E.; Moon, B.; Lee, S.

Plant Pathol. J. (Seoul, Repub. Korea) 26 (2), 170177.

2010 Mar 21

Identification and control of impurities in streptomycin sulfate by high-performance liquid chromatography coupled with mass detection and corona charged-aerosol detection.

Holzgrabe, U.; Nap, C. J.; Kunz, N.; Almeling, S.

J. Pharm. Biomed. Anal. 56 (2), 271279.

2011 Sep 10

The effect of composting on the degradation of a veterinary pharmaceutical.

Jayashree, R.; Prasher, S.; Patel, R.; Hussain, S.; Barrington, S.

Bioresour. Technol. 101 (7), 22942299.

2010 Apr

Effect of soil pH on sorption of salinomycin in clay and sandy soils.

Jayashree, R.; Prasher, S.; Rajvinder, K.; Patel, R.

Afr. J. Environ. Sci. Technol. 5 (9), 661667.

2011 Sep

Combined application of dispersive liquid-liquid microextraction based on the solidification of floating organic droplets and charged aerosol detection for the simple and sensitive quantification of macrolide antibiotics in human urine.

Jia, S.; Li, J.; Park, S. R.; Ryu, Y.; Park, I. H.; Park, J. H.; Hong, S. S.; Kwon, S. W.; Lee, J.

J. Pharm. Biomed. Anal. 86C, 204213.

2013 Dec

Development and validation of a RP-HPLC method for the estimation of netilmicin sulfate and its related substances using charged aerosol detection.

Joseph, A.; Patel, S.; Rustum, A. J. Chromatogr. Sci. 48 (7), 607612.

2010 Aug

Development and validation of a RP-HPLC method for the determination of gentamicin sulfate and its related substances in a pharmaceutical cream using a short pentafluorophenyl column and a charged aerosol detector.

Joseph, A.; Rustum, A. J. Pharm. Biomed. Anal. 51 (3), 521531.

2010 Feb 5

http://www.google.com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=1&ved=0CC0QFjAA&url=http%3A%2F%2Fplantpathologyjournal.org%2Ffolder.php%3Fa%3Ddown%26id%3D77688&ei=--CPUpK4JZPGkQeC_YGoAQ&usg=AFQjCNHUeZ3NuTFdfZBq5GVKDnjAd4j3CAhttp://www.google.com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=1&ved=0CC0QFjAA&url=http%3A%2F%2Fplantpathologyjournal.org%2Ffolder.php%3Fa%3Ddown%26id%3D77688&ei=--CPUpK4JZPGkQeC_YGoAQ&usg=AFQjCNHUeZ3NuTFdfZBq5GVKDnjAd4j3CAhttp://www.ncbi.nlm.nih.gov/pubmed/21665399http://www.ncbi.nlm.nih.gov/pubmed/21665399http://www.ncbi.nlm.nih.gov/pubmed/21665399http://www.ncbi.nlm.nih.gov/pubmed/19944598http://www.ncbi.nlm.nih.gov/pubmed/19944598http://www.ajol.info/index.php/ajest/article/download/72122/61064http://www.ajol.info/index.php/ajest/article/download/72122/61064http://www.ncbi.nlm.nih.gov/pubmed/24013122http://www.ncbi.nlm.nih.gov/pubmed/24013122http://www.ncbi.nlm.nih.gov/pubmed/24013122http://www.ncbi.nlm.nih.gov/pubmed/24013122http://www.ncbi.nlm.nih.gov/pubmed/20819288http://www.ncbi.nlm.nih.gov/pubmed/20819288http://www.ncbi.nlm.nih.gov/pubmed/20819288http://www.ncbi.nlm.nih.gov/pubmed/19815362http://www.ncbi.nlm.nih.gov/pubmed/19815362http://www.ncbi.nlm.nih.gov/pubmed/19815362http://www.ncbi.nlm.nih.gov/pubmed/19815362


Polyketide analysis using mass spectrometry, evaporative light scattering, and charged aerosol detector systems.

Pistorino, M.; Pfeifer, B. A. Anal. Bioanal. Chem. 390 (4), 11891193.

2008 Feb

Determination of gentamicin sulphate composition and related substances in pharmaceutical preparations by LC with charged aerosol detection.

Stypulkowska, K.; Blazewicz, A.; Fijalek, Z.; Sarna, K.

Chromatographia 72 (1112), 12251229.

2010 Dec

Determination of neomycin and related substances in pharmaceutical preparations by reversed-phase high performance liquid chromatography with mass spectrometry and charged aerosol detection.

Stypulkowska, K.; Blazewicz, A.; Fijalek, Z.; Warowna-Grzeskiewicz, M.; Srebrzynska, K.

J. Pharm. Biomed. Anal. 76, 207214.

2013 Mar 25

Biosynthesis of fosfomycin, re-examination and re-confirmation of a unique Fe (II) and NAD (P) H-dependent epoxidation reaction.

Yan, F.; Munos, J.; Liu, P.; Liu, H. Biochemistry 45 (38), 1147311481.

2006 Sep 26

Antibiotics



Proteins/Peptides

http://www.ncbi.nlm.nih.gov/pubmed/18080862http://www.ncbi.nlm.nih.gov/pubmed/18080862http://www.ncbi.nlm.nih.gov/pubmed/21212825http://www.ncbi.nlm.nih.gov/pubmed/21212825http://www.ncbi.nlm.nih.gov/pubmed/21212825http://www.ncbi.nlm.nih.gov/pubmed/23337822http://www.ncbi.nlm.nih.gov/pubmed/23337822http://www.ncbi.nlm.nih.gov/pubmed/23337822http://www.ncbi.nlm.nih.gov/pubmed/23337822http://www.ncbi.nlm.nih.gov/pubmed/16981707http://www.ncbi.nlm.nih.gov/pubmed/16981707http://www.ncbi.nlm.nih.gov/pubmed/16981707



Proteins/Peptides


Carbohydrate and oligosaccharide analysis with a universal HPLC detector.

Asa, D. American Laboratory 38, 16.

2006

Determination of levoglucosan in atmospheric aerosols using high performance liquid chromatography with aerosol charge detection.

Dixon, R. W.; Baltzell, G. J. Chromatogr., A. 1109 (2), 214221.

2006 Mar 24

Composition of structural carbohydrates in biomass: Precision of a liquid chromatography method using a neutral detergent extraction and a charged aerosol detector.

Godin, B.; Agneessens, R.; Gerin, P. A.; Delcarte, J.

Talanta 85 (4), 20142026. 2011 Sep 30

Selectivity issues in targeted metabolomics: Separation of phosphorylated carbohydrate isomers by mixed-mode hydrophilic interaction/weak anion exchange chromatography.

Hinterwirth, H.; Lmmerhofer, M.; Preinerstorfer, B.; Gargano, A.; Reischl, R.; Bicker, W.; Trapp, O.; Brecker, L.; Lindner, W.

J. Sep. Sci. 33 (21), 32733282.

2010 Nov

Investigation of polar organic solvents compatible with Corona charged aerosol detection and their use for the determination of sugars by hydrophilic interaction liquid chromatography.

Hutchinson, J. P.; Remenyi, T.; Nesterenko, P.; Farrell, W.; Groeber, E.; Szucs, R.; Dicinoski, G.; Haddad, P. R.

Anal. Chim. Acta. 750, 199206.

2012 Oct 31

Characterization of an endoglucanase belonging to a new subfamily of glycoside hydrolase family 45 of the basidiomycete Phanerochaete chrysosporium.

Igarashi, K.; Ishida, T.; Hori, C.; Samejima, M.

Appl. Environ. Microbiol. 74 (18), 56285634.

2008 Sep

Direct detection method of oligosaccharides by high-performance liquid chromatography with charged aerosol detection.

Inagaki, S.; Min, J. Z.; Toyooka, T. Biomed. Chromatogr. 21 (4), 338342.

2007 Apr

Differential selectivity of the Escherichia coli cell membrane shifts the equilibrium for the enzyme-catalyzed isomerization of galactose to tagatose.

Kim, J. H.; Lim, B. C.; Yeom, S. J.; Kim, Y. S.; Kim, H. J.; Lee, J. K.; Lee, S. H.; Kim, S. W.; Oh, D. K.


2008 Apr

Elution strategies for reversed-phase high-performance liquid chromatography analysis of sucrose alkanoate regioisomers with charged aerosol detection.

Lie, A.; Pedersen, L. H. J. Chromatogr., A. 1311, 127133.

2013 Oct 11

Carbohydrates

http://www.americanlaboratory.com/http://www.americanlaboratory.com/http://www.ncbi.nlm.nih.gov/pubmed/16448658http://www.ncbi.nlm.nih.gov/pubmed/16448658http://www.ncbi.nlm.nih.gov/pubmed/16448658http://www.ncbi.nlm.nih.gov/pubmed/21872053http://www.ncbi.nlm.nih.gov/pubmed/21872053http://www.ncbi.nlm.nih.gov/pubmed/21872053http://www.ncbi.nlm.nih.gov/pubmed/20928924http://www.ncbi.nlm.nih.gov/pubmed/20928924http://www.ncbi.nlm.nih.gov/pubmed/20928924http://www.ncbi.nlm.nih.gov/pubmed/23062441http://www.ncbi.nlm.nih.gov/pubmed/23062441http://www.ncbi.nlm.nih.gov/pubmed/23062441http://www.ncbi.nlm.nih.gov/pubmed/18676702http://www.ncbi.nlm.nih.gov/pubmed/18676702http://www.ncbi.nlm.nih.gov/pubmed/18676702http://www.ncbi.nlm.nih.gov/pubmed/17236241http://www.ncbi.nlm.nih.gov/pubmed/17236241http://www.ncbi.nlm.nih.gov/pubmed/17236241http://www.ncbi.nlm.nih.gov/pubmed/18263746http://www.ncbi.nlm.nih.gov/pubmed/18263746http://www.ncbi.nlm.nih.gov/pubmed/18263746http://www.ncbi.nlm.nih.gov/pubmed/24011419http://www.ncbi.nlm.nih.gov/pubmed/24011419http://www.ncbi.nlm.nih.gov/pubmed/24011419

Carbohydrates



Proteins/Peptides


Design of experiments and multivariate analysis for evaluation of reversed-phase high-performance liquid chromatography with charged aerosol detection of sucrose caprate regioisomers.

Lie, A.; Wimmer, R.; Pedersen, L. H.

J. Chromatogr., A. 1281, 6772.

2013 Mar 15

Solvent effects on the retention of oligosaccharides in porous graphitic carbon liquid chromatography.

Melmer, M.; Stangler, T.; Premstaller, A.; Lindner, W.

J. Chromatogr., A 1217 (39) 60926096.

2010 Sep 24

Practical preparation of lacto-N-biose I, a candidate for the bifidus factor in human milk.

Nishimoto, M.; Kitaoka, M. Biosci., Biotechnol., Biochem. 71 (8), 21012104.

2007 Aug

Cellotriose and cellotetraose as inducers of the genes encoding cellobiohydrolases in the basidiomycete Phanerochaete chrysosporium.

Suzuki, H.; Igarashi, K.; Samejima, M.


2010 Sep

1,2-alpha-l-Fucosynthase: A glycosynthase derived from an inverting alpha-glycosidase with an unusual reaction mechanism.

Wada, J.; Honda, Y.; Nagae, M.; Kato, R.; Wakatsuki, S.; Katayama, T.; Taniguchi, H.; Kumagai, H.; Kitaoka, M.; Yamamoto, K.

FEBS Lett. 582 (27), 37393743.

2008 Nov 12

Efficient separation of oxidized cello-oligosaccharides generated by cellulose degrading lytic polysaccharide monooxygenases.

Westereng, B.; Agger, J. W.; Horn, S. J.; Vaaje-Kolstad, G.; Aachmann, F. L.; Stenstrm, Y. H.; Eijsink, V. G.

J. Chromatogr., A. 1271 (1), 144152.

2013 Jan 4

Distribution of in vitro fermentation ability of lacto-N-Biose I, a major building block of human milk oligosaccharides, in bifidobacterial strains.

Xiao, J. Z.; Takahashi, S.; Nishimoto, M.; Odamaki, T.; Yaeshima, T.; Iwatsuki, K.; Kitaoka, M.


2010 Jan

http://www.ncbi.nlm.nih.gov/pubmed/23411148http://www.ncbi.nlm.nih.gov/pubmed/23411148http://www.ncbi.nlm.nih.gov/pubmed/23411148http://www.ncbi.nlm.nih.gov/pubmed/23411148http://www.ncbi.nlm.nih.gov/pubmed/20800844http://www.ncbi.nlm.nih.gov/pubmed/20800844http://www.ncbi.nlm.nih.gov/pubmed/17690443http://www.ncbi.nlm.nih.gov/pubmed/17690443http://www.ncbi.nlm.nih.gov/pubmed/20656867http://www.ncbi.nlm.nih.gov/pubmed/20656867http://www.ncbi.nlm.nih.gov/pubmed/20656867http://www.ncbi.nlm.nih.gov/pubmed/18845150http://www.ncbi.nlm.nih.gov/pubmed/18845150http://www.ncbi.nlm.nih.gov/pubmed/18845150http://www.ncbi.nlm.nih.gov/pubmed/23246088http://www.ncbi.nlm.nih.gov/pubmed/23246088http://www.ncbi.nlm.nih.gov/pubmed/23246088http://www.ncbi.nlm.nih.gov/pubmed/19854932http://www.ncbi.nlm.nih.gov/pubmed/19854932http://www.ncbi.nlm.nih.gov/pubmed/19854932



Proteins/Peptides


Dilute-and-shoot triple parallel mass spectrometry method for analysis of vitamin D and triacylglycerols in dietary supplements.

Byrdwell, W. C. Anal. Bioanal. Chem. 401 (10), 33173334.

2011 Dec

Photostability of rebaudioside A and stevioside in beverages. Clos, J. F.; Dubois, G. E.; Prakash, I.

J. Agric. Food Chem. 56 (18), 85078513.

2008 Sep 24

Assessment of microcystin purity using charged aerosol detection.

Edwards, C.; Lawton, L. A. J. Chromatogr., A. 1217 (32), 52335238.

2010 Aug 6

Charged aerosol detection to characterize components of dispersed-phase formulations.

Fox, C. B.; Sivananthan, S. J.; Mikasa, T. J.; Lin, S.; Parker, S. C.

Adv. Colloid Interface Sci. 199200, 5965.

2013 Nov

Determination of water-soluble vitamins in infant milk and dietary supplement using a liquid chromatography on-line coupled to a corona-charged aerosol detector.

Mrquez-Sillero, I.; Crdenas, S.; Valcrcel, M.

J. Chromatogr., A. 1313C, 253258.

2013 Oct 25

Practical preparation of lacto-N-biose I, a candidate for the bifidus factor in human milk.

Nishimoto, M.; Kitaoka, M. Biosci., Biotechnol., Biochem. 71 (8), 2101-2104.

2007 Aug

Hydrophilic interaction liquid chromatographycharged aerosol detection as a straightforward solution for simultaneous analysis of ascorbic acid and dehydroascorbic acid.

Novkov, L.; Solichov, D.; Solich, P.

J. Chromatogr., A. 1216 (21), 45744581.

2009 May 22

Food/Nutrition

http://www.ncbi.nlm.nih.gov/pubmed/21964772http://www.ncbi.nlm.nih.gov/pubmed/21964772http://www.ncbi.nlm.nih.gov/pubmed/21964772http://www.ncbi.nlm.nih.gov/pubmed/18717571http://www.ncbi.nlm.nih.gov/pubmed/20615509http://www.ncbi.nlm.nih.gov/pubmed/20615509http://www.ncbi.nlm.nih.gov/pubmed/23855968http://www.ncbi.nlm.nih.gov/pubmed/23855968http://www.ncbi.nlm.nih.gov/pubmed/23726354http://www.ncbi.nlm.nih.gov/pubmed/23726354http://www.ncbi.nlm.nih.gov/pubmed/23726354http://www.ncbi.nlm.nih.gov/pubmed/17690443http://www.ncbi.nlm.nih.gov/pubmed/17690443http://www.ncbi.nlm.nih.gov/pubmed/19358994http://www.ncbi.nlm.nih.gov/pubmed/19358994http://www.ncbi.nlm.nih.gov/pubmed/19358994http://www.ncbi.nlm.nih.gov/pubmed/19358994



Proteins/Peptides


Comprehensive impurity profiling of nutritional infusion solutions by multidimensional off-line reversed-phase liquid chromatography hydrophilic interaction chromatography-ion trap mass-spectrometry and charged aerosol detection with universal calibration.

Schiesel, S.; Lmmerhofer, M.; Lindner, W.

J. Chromatogr., A. 1259, 10010.

2012 Oct 12

Direct separation and detection of biogenic amines by ion-pair liquid chromatography with chemiluminescent nitrogen detector.

Sun, J.; Guo, H. X.; Semin, D.; Cheetham, J.

J. Chromatogr., A. 1218 (29), 46894697.

2011 Jul 22

Simultaneous sampling of volatile and non-volatile analytes in beer for fast fingerprinting by extractive electrospray ionization mass spectrometry.

Zhu, L.; Hu, Z.; Gamez, G.; Law, W. S.; Chen, H.; Yang, S.; Chingin, K.; Balabin, R. M.; Wang, R.; Zhang, T.; Zenobi, R.

Anal. Bioanal. Chem. 398 (1), 405413.

2010 Sep

Food/Nutrition

http://www.ncbi.nlm.nih.gov/pubmed/22284534http://www.ncbi.nlm.nih.gov/pubmed/22284534http://www.ncbi.nlm.nih.gov/pubmed/22284534http://www.ncbi.nlm.nih.gov/pubmed/22284534http://www.ncbi.nlm.nih.gov/pubmed/22284534http://www.ncbi.nlm.nih.gov/pubmed/21665217http://www.ncbi.nlm.nih.gov/pubmed/21665217http://www.ncbi.nlm.nih.gov/pubmed/21665217http://www.ncbi.nlm.nih.gov/pubmed/20644917http://www.ncbi.nlm.nih.gov/pubmed/20644917http://www.ncbi.nlm.nih.gov/pubmed/20644917



Proteins/Peptides


From lipid analysis towards lipidomics, a new challenge for the analytical chemistry of the 21st century. Part I: Modern lipid analysis.

Carrasco-Pancorbo, A.; Navas-Iglesias, N.; Cuadros-Rodrguez, L.

TrAC, Trends Anal. Chem. 28 (3), 263278.

2009 Mar

Improving the universal response of evaporative light scattering detection by mobile phase compensation.

de Villiers, A.; Grecki, T.; Lynen, F.; Szucs, R.; Sandra, P.

J. Chromatogr., A. 1161 (12), 183191.

2007 Aug 17

Development and testing of a detection method for liquid chromatography based on aerosol charging.

Dixon, R. W.; Peterson, D. S. Anal. Chem. 74 (13), 29302937.

2002 Jul 1

Charged aerosol detection to characterize components of dispersed-phase formulations.

Fox, C. B.; Sivananthan, S. J.; Mikasa, T. J.; Lin, S.; Parker, S. C.

Adv. Colloid Interface Sci. 199200, 5965.

2013 Nov

HPLC analysis of nonvolatile analytes using charged aerosol detection.

Gamache, P.; McCarthy, R.; Freeto, S. M.; Asa, D.; Woodcock, M.; Laws, K.; Cole, R.

LC-GC North America 23, 150161.

2005 Feb 1

Universal response in liquid chromatography using charged aerosol detection.

Grecki, T.; Lynen, F.; Szucs, R.; Sandra, P.

Anal. Chem. 78 (9), 31863192.

2006 May 1

Comparison of universal detectors for high-temperature micro liquid chromatography.

Hazotte, A.; Libong, D.; Matoga, M.; Chaminade, P.

J. Chromatogr., A. 1170 (12), 5261.

2007 Nov 2

Comparison of the response of four aerosol detectors used with ultra high pressure liquid chromatography.

Hutchinson, J. P.; Li, J.; Farrell, W.; Groeber, E.; Szucs, R.; Dicinoski, G.; Haddad, P. R.

J. Chromatogr., A. 1218 (12), 16461655.

2011 Mar 25

Universal response model for a corona charged aerosol detector.

Hutchinson, J. P.; Li, J.; Farrell, W.; Groeber, E.; Szucs, R.; Dicinoski, G.; Haddad, P. R.

J. Chromatogr., A. 1217 (47), 74187427.

2010 Nov 19

General

http://www.sciencedirect.com/science/article/pii/S0165993608002811http://www.sciencedirect.com/science/article/pii/S0165993608002811http://www.sciencedirect.com/science/article/pii/S0165993608002811http://www.ncbi.nlm.nih.gov/pubmed/17568599http://www.ncbi.nlm.nih.gov/pubmed/17568599http://www.ncbi.nlm.nih.gov/pubmed/12141649http://www.ncbi.nlm.nih.gov/pubmed/12141649http://www.ncbi.nlm.nih.gov/pubmed/23855968http://www.ncbi.nlm.nih.gov/pubmed/23855968http://www.chromatographyonline.com/lcgc/Liquid+Chromatography+(LC%2FHPLC)/HPLC-Analysis-of-Nonvolatile-Analytes-Using-Charge/ArticleStandard/Article/detail/147866http://www.chromatographyonline.com/lcgc/Liquid+Chromatography+(LC%2FHPLC)/HPLC-Analysis-of-Nonvolatile-Analytes-Using-Charge/ArticleStandard/Article/detail/147866http://www.ncbi.nlm.nih.gov/pubmed/16643012http://www.ncbi.nlm.nih.gov/pubmed/16643012http://www.ncbi.nlm.nih.gov/pubmed/17905258http://www.ncbi.nlm.nih.gov/pubmed/17905258http://www.ncbi.nlm.nih.gov/pubmed/21315361http://www.ncbi.nlm.nih.gov/pubmed/21315361http://www.ncbi.nlm.nih.gov/pubmed/20961549http://www.ncbi.nlm.nih.gov/pubmed/20961549



Proteins/Peptides


Effects of eluent temperature and elution bandwidth on detection response for aerosol-based detectors.

Khandagale, M. M.; Hutchinson, J. P.; Dicinoski, G. W.; Haddad, P. R.

J. Chromatogr., A. 1308, 96103.

2013 Sep 20

Development and evaluation of Corona charged aerosol detection (CAD): A new universal detector for HPLC.

McCarthy, R.; Gamache, P.; Asa, D.

LabPlus international. 2005 Jun

Comparison of the sensitivity of evaporative universal detectors and LC/MS in the HILIC and the reversed-phase HPLC modes.

Mitchell, C. R.; Bao, Y.; Benz, N. J.; Zhang, S.

J. Chromatogr., B: Anal. Technol. Biomed. Life Sci. 877 (32), 41334139.

2009 Dec 15

The successful implementation of Corona CAD technology in HPLC laboratories across a wide range of industries.

Ramsey, N. Chromatography 27 (Suppl. 2), 7778.

2006

A new universal detector, Corona charged aerosol detection. Senda, M.; Fukushima, K.; Hashiguchi, K.; Matsumoto, T.; Gamache, P.; Waraska, J.; Asa, D.

Chromatography 27 (3), 119124.

2006

A new universal detector, Corona charged aerosol detector and its applications.

Senda, M.; Kanedai, Y.; Fukushima, K.; Hirose, K.; Hashiguchi, K.; Matsumoto, T.

Chromatography 27 (Suppl. 1), 3942.

2006

Evaluation of column bleed by using an ultraviolet and a charged aerosol detector coupled to a high-temperature liquid chromatographic system.

Teutenberg, T.; Tuerk, J.; Holzhauser, M.; Kiffmeyer, T. K.

J. Chromatogr., A. 1119 (12), 197201.

2006 Jun 30

Review of operating principle and applications of the charged aerosol detector.

Vehovec, T.; Obreza, A. J. Chromatogr., A. 1217 (10), 15491556.

2010 Mar 5

Performance evaluation of evaporative light scattering detection and charged aerosol detection in reversed phase liquid chromatography.

Vervoort, N.; Daemen, D.; Trk, G.

J. Chromatogr., A. 1189 (12), 92100.

2008 May 2

Determination of relative response factors for chromatographic investigations using NMR spectrometry.

Webster, G. K.; Marsden, I.; Pommerening, C. A.; Tyrakowski, C. M.; Tobias, B.


2009 Jul 12

General

http://www.ncbi.nlm.nih.gov/pubmed/23953611http://www.ncbi.nlm.nih.gov/pubmed/23953611http://www.labint-online.com/uploads/tx_ttproducts/datasheet/development-and-evaluation-of-corona-charged-aerosol-detection-(cad)-a-new-universal-detector-for-hplc.pdfhttp://www.labint-online.com/uploads/tx_ttproducts/datasheet/development-and-evaluation-of-corona-charged-aerosol-detection-(cad)-a-new-universal-detector-for-hplc.pdfhttp://www.ncbi.nlm.nih.gov/pubmed/19926350http://www.ncbi.nlm.nih.gov/pubmed/19926350http://www.ncbi.nlm.nih.gov/pubmed/19926350http://sciencelinks.jp/j-east/article/200624/000020062406A0875411.phphttp://sciencelinks.jp/j-east/article/200624/000020062406A0875411.phphttp://sciencelinks.jp/j-east/article/200704/000020070407A0087234.phphttp://sciencelinks.jp/j-east/article/200613/000020061306A0444637.phphttp://sciencelinks.jp/j-east/article/200613/000020061306A0444637.phphttp://www.ncbi.nlm.nih.gov/pubmed/16378619http://www.ncbi.nlm.nih.gov/pubmed/16378619http://www.ncbi.nlm.nih.gov/pubmed/16378619http://www.ncbi.nlm.nih.gov/pubmed/20083252http://www.ncbi.nlm.nih.gov/pubmed/20083252http://www.ncbi.nlm.nih.gov/pubmed/18054946http://www.ncbi.nlm.nih.gov/pubmed/18054946http://www.ncbi.nlm.nih.gov/pubmed/18054946http://www.ncbi.nlm.nih.gov/pubmed/19345032http://www.ncbi.nlm.nih.gov/pubmed/19345032



Proteins/Peptides


Development of analytical procedures to study changes in the composition of meat phospholipids caused by induced oxidation.

Cascone, A.; Eerola, S.; Ritieni, A.; Rizzo, A.

J. Chromatogr., A 1120 (12), 211220.

2006 Jul 7

Evaporative light scattering and charged aerosol detector. Chaminade, P. Chapter 5. In Hyphenated and Alternative Methods of Detection in Chromatography, Chromatographic Science Series; Shalliker, A., Ed.; Taylor & Francis Group, LLC: Boca Raton, FL.; 145160.

2012

Simple and efficient profiling of phospholipids in phospholipase D-modified soy lecithin by HPLC with charged aerosol detection.

Damnjanovic, J.; Nakano, H.; Iwasaki, Y.

J. Am. Oil Chem. Soc. 90 (7), 951957.

2013 Jul

Discriminating olive and non-olive oils using HPLC-CAD and chemometrics.

de la Mata-Espinosa, P.; Bosque-Sendra, J. M.; Bro, R.; Cuadros-Rodrguez, L.

Anal. Bioanal. Chem. 399 (6), 20832092.

2011 Feb

Olive oil quantification of edible vegetable oil blends using triacylglycerols chromatographic fingerprints and chemometric tools.

de la Mata-Espinosa, P.; Bosque-Sendra, J. M.; Bro, R.; Cuadros-Rodrguez, L.

Talanta 85 (1), 177182. 2011 Jul 15

Quantification of triacylglycerols in olive oils using HPLC-CAD. de la Mata-Espinosa, P.; Bosque-Sendra, J.; Cuadros-Rodriguez, L.

Food Analytical Methods 4 (4), 574581.

2011 Dec

Lipids

http://www.ncbi.nlm.nih.gov/pubmed/16630622http://www.ncbi.nlm.nih.gov/pubmed/16630622http://www.ncbi.nlm.nih.gov/pubmed/16630622http://www.crcpress.com/product/isbn/9780849390777http://link.springer.com/article/10.1007%2Fs11746-013-2236-xhttp://link.springer.com/article/10.1007%2Fs11746-013-2236-xhttp://link.springer.com/article/10.1007%2Fs11746-013-2236-xhttp://www.ncbi.nlm.nih.gov/pubmed/21060998http://www.ncbi.nlm.nih.gov/pubmed/21060998http://www.ncbi.nlm.nih.gov/pubmed/21645687http://www.ncbi.nlm.nih.gov/pubmed/21645687http://www.ncbi.nlm.nih.gov/pubmed/21645687http://link.springer.com/article/10.1007%2Fs12161-011-9207-3



Proteins/Peptides


Quantification of pegylated phospholipids decorating polymeric microcapsules of perfluorooctyl bromide by reverse phase HPLC with a charged aerosol detector.

Daz-Lpez, R.; Libong, D.; Tsapis, N.; Fattal, E.; Chaminade, P.


2008 Nov 4

Squalene emulsions for parenteral vaccine and drug delivery. Fox, C. B. Molecules 14 (9), 32863312.

2009 Sep 1

Interactions between parenteral lipid emulsions and container surfaces.

Gonyon, T.; Tomaso, A.; Kotha, P.; Owen, H.; Patel, D.; Carter, P.; Cronin, J.; Green, J.

PDA J. Pharm. Sci. and Tech. 67 (3), 247254.

2013 MayJun

Composition analysis of positional isomers of phosphatidylinositol by high-performance liquid chromatography.

Iwasaki, Y.; Masayama, A.; Mori, A.; Ikeda, C.; Nakano, H.

J. Chromatogr., A 1216 (32), 60776080.

2009 Aug 7

Determination of phospholipid and its degradation products in liposomes for injection by HPLC-charged aerosol detection (CAD).

Jiang, Q.; Yang, R.; Mei, X. Chinese Pharmaceutical Journal (Zhongguo Yaoxue Zazhi, Beijing, China) 42 (23), 17941796.

2007

Rapid quantification of yeast lipid using microwave-assisted total lipid extraction and HPLC-CAD.

Khoomrung, S.; Chumnanpuen, P.; Jansa-Ard, S.; Sthlman, M.; Nookaew, I.; Born, J.; Nielsen, J.

Anal. Chem. 85 (10), 49124919.

2013 May 21

A new liquid chromatography method with charge aerosol detector (CAD) for the determination of phospholipid classes. Application to milk phospholipids.

Kieibowicz, G.; Micek, P.; Wawrzenczyk, C.

Talanta 105, 2833. 2013 Feb 15

Lipids

http://www.ncbi.nlm.nih.gov/pubmed/18818041http://www.ncbi.nlm.nih.gov/pubmed/18818041http://www.ncbi.nlm.nih.gov/pubmed/18818041http://www.mdpi.com/1420-3049/14/9/3286http://www.ncbi.nlm.nih.gov/pubmed/23752751http://www.ncbi.nlm.nih.gov/pubmed/23752751http://www.ncbi.nlm.nih.gov/pubmed/19580974http://www.ncbi.nlm.nih.gov/pubmed/19580974http://www.ncbi.nlm.nih.gov/pubmed/19580974http://caod.oriprobe.com/articles/277680/Determination_of_Phospholipid_and_Its_Degradation_Products_in_Liposome.htmhttp://caod.oriprobe.com/articles/277680/Determination_of_Phospholipid_and_Its_Degradation_Products_in_Liposome.htmhttp://caod.oriprobe.com/articles/277680/Determination_of_Phospholipid_and_Its_Degradation_Products_in_Liposome.htmhttp://caod.oriprobe.com/journals/zgyxzz/%e4%b8%ad%e5%9b%bd%e8%8d%af%e5%ad%a6%e6%9d%82%e5%bf%97.htmhttp://caod.oriprobe.com/journals/zgyxzz/%e4%b8%ad%e5%9b%bd%e8%8d%af%e5%ad%a6%e6%9d%82%e5%bf%97.htmhttp://www.ncbi.nlm.nih.gov/pubmed/23634639http://www.ncbi.nlm.nih.gov/pubmed/23634639http://www.sciencedirect.com/science/article/pii/S0039914012010041http://www.sciencedirect.com/science/article/pii/S0039914012010041http://www.sciencedirect.com/science/article/pii/S0039914012010041


An LC method for the analysis of phosphatidylcholine hydrolysis products and its application to the monitoring of the acyl migration process.

Kiebowicz, G.; Smuga, D.; Gadkowski, W.; Chojnacka, A.; Wawrzenczyk, C.

Talanta 94, 2229. 2012 May 30

Separation of acylglycerols, FAME and FFA in biodiesel by size exclusion chromatography.

Kittirattanapiboon, K.; Krisnangkur, K.

Eur. J. Lipid Sci. Technol. 110 (5), 422427.

2008 Mar 17

Quantitation of triacylglycerols from plant oils using charged aerosol detection with gradient compensation.

Lsa, M.; Lynen, F.; Holcapek, M.; Sandra, P.

J. Chromatogr., A. 1176 (12), 135142.

2007 Dec 28

Quantitative study of the stratum corneum lipid classes by normal phase liquid chromatography: comparison between two universal detectors.

Merle, C.; Laugel, C.; Chaminade, P.; Baillet-Guffroy, A.

J. Liq. Chromatogr. Relat. Technol. 33, 629644.

2010 Mar

The analysis of lipids via HPLC with a charged aerosol detector.

Moreau, R. A. Lipids 41 (7), 72734. 2006 Jul

Lipid analysis via HPLC with a charged aerosol detector. Moreau, R. A. Lipid Technol. 21 (89), 191194.

2009 Oct 23

Extraction and analysis of food lipids. Moreau, R. A.; Winkler-Moser, J. K.

Chapter 6. In Methods of Analysis of Food Components and Additives, Second Edition; tles, S., Ed.; Taylor & Francis Group, LLC: Boca Raton, FL.; 115134.

2011 Nov

Aerosol based detectors for the investigation of phospholipid hydrolysis in a pharmaceutical suspension formulation.

Nair, L.; Werling, J. J. Pharm. Biomed. Anal. 49 (1), 9599.

2009 Jan 15



Proteins/Peptides

Lipids

http://www.ncbi.nlm.nih.gov/pubmed/22608409http://www.ncbi.nlm.nih.gov/pubmed/22608409http://www.ncbi.nlm.nih.gov/pubmed/22608409http://onlinelibrary.wiley.com/doi/10.1002/ejlt.200700164/abstracthttp://onlinelibrary.wiley.com/doi/10.1002/ejlt.200700164/abstracthttp://www.ncbi.nlm.nih.gov/pubmed/18021788http://www.ncbi.nlm.nih.gov/pubmed/18021788http://www.tandfonline.com/doi/abs/10.1080/10826071003608520#previewhttp://www.tandfonline.com/doi/abs/10.1080/10826071003608520#previewhttp://www.tandfonline.com/doi/abs/10.1080/10826071003608520#previewhttp://www.ncbi.nlm.nih.gov/pubmed/17069357http://www.ncbi.nlm.nih.gov/pubmed/17069357http://onlinelibrary.wiley.com/doi/10.1002/lite.200900048/abstracthttp://www.crcnetbase.com/isbn/9781439815533http://www.ncbi.nlm.nih.gov/pubmed/19070982http://www.ncbi.nlm.nih.gov/pubmed/19070982


Structure/function relationships of adipose phospholipase A2 containing a cys-his-his catalytic triad.

Pang, X. Y.; Cao, J.; Addington, L.; Lovell, S.; Battaile, K. P.; Zhang, Rao, J. L.; Dennis, E. A.; Moise, A. R.

J. Biol. Chem. 287 (42), 3526035274.

2012 Oct 12

Simultaneous assessment of lipid classes and bile acids in human intestinal fluid by solid-phase extraction and HPLC methods.

Persson, E.; Lfgren, L.; Hansson, G.; Abrahamsson, B.; Lennerns, H.; Nilsson, R.

J. Lipid Res. 48 (1), 242251.

2007 Jan

The use of charged aerosol detection with HPLC for the measurement of lipids.

Plante, M.; Bailey, B.; Acworth, I. Methods Mol. Biol. (Totowa, NJ, U.S.) 579, 469482.

2009

Comparison between charged aerosol detection and light scattering detection for the analysis of Leishmania membrane phospholipids.

Ramos, R. G.; Libong, D.; Rakotomanga, M.; Gaudin, K.; Loiseau, P. M.; Chaminade, P.

J. Chromatogr., A. 1209 (12), 8894.

2008 Oct 31

Authentication of geographical origin of palm oil by chromatographic fingerprinting of triacylglycerols and partial least square-discriminant analysis.

Ruiz-Sambls, C.; Arrebola-Pascual, C.; Tres, A.; van Ruth, S.; Cuadros-Rodrguez, L.

Talanta. 116, 788793. 2013 Nov 15

Simple and precise detection of lipid compounds present within liposomal formulations using a charged aerosol detector.

Schnherr, C.; Touchene, S.; Wilser, G.; Peschka-Sss, R.; Francese, G.

J. Chromatogr., A. 1216 (5), 781786.

2009 Jan 30

Determination of intralumenal individual bile acids by HPLC with charged aerosol detection.

Vertzoni, M.; Archontaki, H.; Reppas, C.

J. Lipid Res. 49 (12), 26902695.

2008 Dec

Neurolipids and the use of a charged aerosol detector. Waraska, J.; Acworth, I. Am. Biotechnol. Lab. 26 (1), 1213.

2008



Proteins/Peptides

Lipids

http://www.ncbi.nlm.nih.gov/pubmed/22923616http://www.ncbi.nlm.nih.gov/pubmed/22923616http://www.ncbi.nlm.nih.gov/pubmed/17062898http://www.ncbi.nlm.nih.gov/pubmed/17062898http://www.ncbi.nlm.nih.gov/pubmed/17062898http://www.ncbi.nlm.nih.gov/pubmed/19763490http://www.ncbi.nlm.nih.gov/pubmed/19763490http://www.ncbi.nlm.nih.gov/pubmed/18823632http://www.ncbi.nlm.nih.gov/pubmed/18823632http://www.ncbi.nlm.nih.gov/pubmed/18823632http://www.ncbi.nlm.nih.gov/pubmed/24148475http://www.ncbi.nlm.nih.gov/pubmed/24148475http://www.ncbi.nlm.nih.gov/pubmed/24148475http://www.ncbi.nlm.nih.gov/pubmed/19091321http://www.ncbi.nlm.nih.gov/pubmed/19091321http://www.ncbi.nlm.nih.gov/pubmed/19091321http://www.ncbi.nlm.nih.gov/pubmed/18693215http://www.ncbi.nlm.nih.gov/pubmed/18693215http://www.bldss.bl.uk/BLDSS/#/New Order/0


Improving the universal response of evaporative light scattering detection by mobile phase compensation.

de Villiers, A.; Grecki, T.; Lynen, F.; Szucs, R.; Sandra, P.

J. Chromatogr., A 1161 (12), 183191.

2007 Aug 17




2008 Nov 4

Phospholipid decoration of microcapsules containing perfluorooctyl bromide used as ultrasound contrast agents.

Daz-Lpez, R.; Tsapis, N.; Libong, D.; Chaminade, P.; Connan, C.; Chehimi, M. M.; Berti, R.; Taulier, N.; Urbach, W.; Nicolas, V.; Fattal, E.

Biomaterials 30 (8), 14621472.

2009 Mar

Aerosol-based detectors for liquid chromatography: Do they have a role in bioanalysis?

Dixon, R. W. Bioanalysis 1 (8), 13891392.

2009 Nov


Grecki, T.; Lynen, F.; Szucs, R.; Sandra, P.

Anal. Chem. 78 (9), 31863192.

2006 May 1

Comparison of universal detectors for high-temperature micro liquid chromatography.

Hazotte, A.; Libong, D.; Matoga, M.; Chaminade, P.

J. Chromatogr., A 1170 (12), 5261.

2007 Nov 2

Characterization of an endoglucanase belonging to a new subfamily of glycoside hydrolase family 45 of the basidiomycete Phanerochaete chrysosporium.

Igarashi, K.; Ishida, T.; Hori, C.; Samejima, M.


2008 Sep

Serial coupling of reversed-phase and hydrophilic interaction liquid chromatography to broaden the elution window for the analysis of pharmaceutical compounds.

Louw, S.; Pereira, A. S.; Lynen, F.; Hanna-Brown, M.; Sandra, P.

J. Chromatogr., A 1208 (1-2), 9094.

2008 Oct 24

Determination of parabens in cosmetic products using multi-walled carbon nanotubes as solid phase extraction sorbent and corona-charged aerosol detection system.

Mrquez-Sillero, I.; Aguilera-Herrador, E.; Crdenas, S.; Valcrcel, M.

J. Chromatogr., A. 1217 (1), 16.

2010 Jan 1



Proteins/Peptides

Miscellaneous

http://www.ncbi.nlm.nih.gov/pubmed/17568599http://www.ncbi.nlm.nih.gov/pubmed/17568599http://www.ncbi.nlm.nih.gov/pubmed/18818041http://www.ncbi.nlm.nih.gov/pubmed/18818041http://www.ncbi.nlm.nih.gov/pubmed/18818041http://www.sciencedirect.com/science/article/pii/S0142961208009253http://www.sciencedirect.com/science/article/pii/S0142961208009253http://www.ncbi.nlm.nih.gov/pubmed/21083086http://www.ncbi.nlm.nih.gov/pubmed/21083086http://www.ncbi.nlm.nih.gov/pubmed/16643012http://www.ncbi.nlm.nih.gov/pubmed/16643012http://www.ncbi.nlm.nih.gov/pubmed/17905258http://www.ncbi.nlm.nih.gov/pubmed/17905258http://www.ncbi.nlm.nih.gov/pubmed/18676702http://www.ncbi.nlm.nih.gov/pubmed/18676702http://www.ncbi.nlm.nih.gov/pubmed/18676702http://www.ncbi.nlm.nih.gov/pubmed/18771775http://www.ncbi.nlm.nih.gov/pubmed/18771775http://www.ncbi.nlm.nih.gov/pubmed/18771775http://www.ncbi.nlm.nih.gov/pubmed/19932486http://www.ncbi.nlm.nih.gov/pubmed/19932486http://www.ncbi.nlm.nih.gov/pubmed/19932486


Bioactive contaminants leach from disposable laboratory plasticware.

McDonald, G. R.; Hudson, A. L.; Dunn, S. M. J.; You, H.; Baker, G. B.; Whittal, R. M.; Martin, J. W.; Jha, A.; Edmondson, D. E.; Holt, A.

Science 322 (5903), 917. 2008 Nov 7

Enzymatic reaction coupled with flow-injection analysis with charged aerosol, coulometric, or amperometric detection for estimation of contamination of the environment by pesticides.

Mikelova, R.; Prokop, Z.; Stejskal, K.; Adam, V.; Beklova, M.; Trnkova, L.; et al.

Chromatographia 67 (Suppl. 1), 4753.

2008 May

Enzymatic reaction coupled with flow-injection analysis with charged aerosol, coulometric, or amperometric detection for estimation of contamination of the environment by pesticides.

Mikelova, R.; Prokop, Z.; Stejskal, K.; Adam, V.; Beklova, M.; Trnkova, L.; Kulichova, B.; Horna, A.; Chaloupkova, R.; Damborsky, J.; Kizek, R.


2008 May 1

Implementation of charged aerosol detection in routine reversed phase liquid chromatography methods.

Reilly, J.; Everatt, B.; Aldcroft, C. J. Liq. Chromatogr. Relat. Technol. 31, 31323142.

2008

The corona charged aerosol detector for liquid chromatography and high field asymmetric waveform ion mobility spectrometry combined with liquid chromatography/mass spectrometry and gas chromatography.

Sherma, J.; Larkin, J. D.; Larkin, F. H.

J. AOAC Int. 89 (1), 15A19A.

2006 JanFeb



Proteins/Peptides

Miscellaneous

http://www.sciencemag.org/content/322/5903/917http://www.sciencemag.org/content/322/5903/917http://link.springer.com/article/10.1365/s10337-008-0590-xhttp://link.springer.com/article/10.1365/s10337-008-0590-xhttp://link.springer.com/article/10.1365/s10337-008-0590-xhttp://link.springer.com/article/10.1365%2Fs10337-008-0590-x#page-1http://link.springer.com/article/10.1365%2Fs10337-008-0590-x#page-1http://link.springer.com/article/10.1365%2Fs10337-008-0590-x#page-1http://www.tandfonline.com/doi/abs/10.1080/10826070802480081?journalCode=ljlc20#previewhttp://www.tandfonline.com/doi/abs/10.1080/10826070802480081?journalCode=ljlc20#previewhttp://www.researchgate.net/publication/232221884_Rapid_purification_method_for_fumonisin_B1_using_centrifugal_partition_chromatographyhttp://www.researchgate.net/publication/232221884_Rapid_purification_method_for_fumonisin_B1_using_centrifugal_partition_chromatographyhttp://www.researchgate.net/publication/232221884_Rapid_purification_method_for_fumonisin_B1_using_centrifugal_partition_chromatographyhttp://www.researchgate.net/publication/232221884_Rapid_purification_method_for_fumonisin_B1_using_centrifugal_partition_chromatography


Validated HPLC method for the quantitative analysis of a 4-methanesulfonyl-piperidine hydrochloride salt.

Soman, A.; Jerfy, M.; Swanek, F. J. Liq. Chromatogr. Relat. Technol. 32 (7), 10001009.

2009 Mar 9

Analysis of quaternary ammonium and phosphonium ionic liquids by reversed-phase high-performance liquid chromatography with charged aerosol detection and unified calibration.

Stojanovic, A.; Lmmerhofer, M.; Kogelnig, D.; Schiesel, S.; Sturm, M.; Galanski, M.; Krachler, R.; Keppler, B. K.; Lindner, W.

J. Chromatogr., A. 1209 (12), 179187.

2008 Oct 31

Determination of relative response factors of impurities in paclitaxel with high performance liquid chromatography equipped with ultraviolet and charged aerosol detectors.

Sun, P.; Wang, X.; Alquier, L.; Maryanoff, C. A.

J. Chromatogr., A 1177 (1), 8791.

2008 Jan 4

Quantitative comparison of a corona-charged aerosol detector and an evaporative light-scattering detector for the analysis of a synthetic polymer by supercritical fluid chromatography.

Takahashi, K.; Kinugasa, S.; Senda, M.; Kimizuka, K.; Fukushima, K.; Matsumoto, T.; Shibata, Y.; Christensen, J.

J. Chromatogr., A 1193 (12), 151155.

2008 Jun 6

Evaluation of column bleed by using an ultraviolet and a charged aerosol detector coupled to a high-temperature liquid chromatographic system.

Teutenberg, T.; Tuerk, J.; Holzhauser, M.; Kiffmeyer, T. K.

J. Chromatogr., A 1119 (12), 197201.

2006 Jun 30

1,2--L-Fucosynthase: A glycosynthase derived from an inverting a-glycosidase with an unusual reaction mechanism.

Wada, J.; Honda, Y.; Nagae, M.; Kato, R.; Wakatsuki, S.; Katayama, T.; Taniguchi, H.; Kumagai, H.; Kitaoka, M.; Yamamoto, K.

FEBS Lett. 582 (27), 37393743.

2008 Nov 12

HPLC determinations of enantiomeric ratios. Wipf, P.; Werner, S.; Twining, L. A.; Kendall, C.

Chirality 19 (1), 59. 2007 Jan



Proteins/Peptides

Miscellaneous

http://www.tandfonline.com/doi/abs/10.1080/10826070902790934http://www.tandfonline.com/doi/abs/10.1080/10826070902790934http://www.ncbi.nlm.nih.gov/pubmed/18805540http://www.ncbi.nlm.nih.gov/pubmed/18805540http://www.ncbi.nlm.nih.gov/pubmed/18805540http://www.ncbi.nlm.nih.gov/pubmed/18805540http://www.ncbi.nlm.nih.gov/pubmed/18067905http://www.ncbi.nlm.nih.gov/pubmed/18067905http://www.ncbi.nlm.nih.gov/pubmed/18067905http://www.ncbi.nlm.nih.gov/pubmed/18439611http://www.ncbi.nlm.nih.gov/pubmed/18439611http://www.ncbi.nlm.nih.gov/pubmed/18439611http://www.ncbi.nlm.nih.gov/pubmed/16378619http://www.ncbi.nlm.nih.gov/pubmed/16378619http://www.ncbi.nlm.nih.gov/pubmed/16378619http://www.febsletters.org/article/S0014-5793(08)00801-6/abstracthttp://www.febsletters.org/article/S0014-5793(08)00801-6/abstracthttp://www.ncbi.nlm.nih.gov/pubmed/17089337



Proteins/Peptides


Aqueous extract of Astragali Radix induces human natriuresis through enhancement of renal response to atrial natriuretic peptide.

Ai, P.; Yong, G.; Dingkun, G.; Qiuyu, Z.; Kaiyuan, Z.; Shanyan, L.

J. Ethnopharmacol. 116 (13), 413421.

2008 Mar 28

Recent methodology in ginseng analysis. Baek, S.; Bae, O.; Park, J. J. Ginseng Res. 36 (2), 119134.

2012 Apr

Sensitive determination of saponins in radix et rhizoma notoginseng by charged aerosol detector coupled with HPLC.

Bai, C.; Han, S.; Chai, X.; Jiang, Y.; Li, P.; Tu, P.

J. Liq. Chromatogr. Relat. Technol. 32 (2), 242260.

2010 Aug 27

The real nature of the indole alkaloids in Cortinarius infractus: Evaluation of artifact formation through solvent extraction method development.

Brondz, I.; Ekeberg, D.; Hiland, K.; Bell, D.; Annino, A.

J. Chromatogr., A 1148 (1), 17.

2007 Apr 27

Chemotaxonomic differentiation between Cortinarius infractus and Cortinarius subtortus by supercritical fluid chromatography connected to a multi-detection system.

Brondz, I.; Hiland, K. Trends Chromatogr. 4, 7987.

2008

Utilization of RP-HPLC fingerprinting analysis for the identification of diterpene glycosides from Stevia rebaudiana.

Chaturvedula, V.; Prakash, I. Int. J. Res. Phytochem. Pharmacol. 1 (2), 8892.

2011 Jun 9

Acid and alkaline hydrolysis studies of stevioside and rebaudioside A.

Chaturvedula, V.; Prakash, I. J. Appl. Pharm. Sci. 1 (8), 104108.

2011 Oct

Spectral analysis and chemical studies of the sweet constituent, rebaudioside A.

Chaturvedula, V.; Prakash, I. Eur. J. Med. Plants 2 (1), 5765.

2012 Feb

Photostability of rebaudioside A and stevioside in beverages. Clos, J. F.; DuBois, G. E.; Prakash, I.

J. Agric. Food Chem. 56 (18), 85078513.

2008 Sep 24

Comparison between evaporative light scattering detection and charged aerosol detection for the analysis of saikosaponins.

Eom, H. Y.; Park, S. Y.; Kim, M. K.; Suh, J. H.; Yeom, H.; Min, J. W.; Kim, U.; Lee, J.; Youm, J. R.; Han, S. B.

J. Chromatogr., A. 1217 (26), 43474354.

2010 Jun 25

HPLC with charged aerosol detection for the measurement of natural products.

Fukushima, K.; Kanedai, Y.; Hirose, K.; Matsumoto, T.; Hashiguchi, K.; Senda, M.; et al.


2006

Natural Products/Supplements

http://www.ncbi.nlm.nih.gov/pubmed/18243612http://www.ncbi.nlm.nih.gov/pubmed/18243612http://www.ncbi.nlm.nih.gov/pubmed/18243612http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3659581/http://www.tandfonline.com/doi/abs/10.1080/10826070802603187http://www.tandfonline.com/doi/abs/10.1080/10826070802603187http://www.ncbi.nlm.nih.gov/pubmed/17391682http://www.ncbi.nlm.nih.gov/pubmed/17391682http://www.ncbi.nlm.nih.gov/pubmed/17391682http://researchtrends.net/tia/abstract.asp?in=0&vn=4&tid=60&aid=2589&pub=2008&type=http://researchtrends.net/tia/abstract.asp?in=0&vn=4&tid=60&aid=2589&pub=2008&type=http://researchtrends.net/tia/abstract.asp?in=0&vn=4&tid=60&aid=2589&pub=2008&type=http://pharmascope.org/ijrpp/index.php?option=com_jdownloads&Itemid=141&view=viewdownload&catid=3&cid=33http://pharmascope.org/ijrpp/index.php?option=com_jdownloads&Itemid=141&view=viewdownload&catid=3&cid=33http://www.japsonline.com/abstract.php?article_id=222http://www.japsonline.com/abstract.php?article_id=222http://www.sciencedomain.org/abstract.php?iid=91&id=13&aid=357#.Us7wbfbnKAwhttp://www.sciencedomain.org/abstract.php?iid=91&id=13&aid=357#.Us7wbfbnKAwhttp://www.ncbi.nlm.nih.gov/pubmed/18717571http://www.ncbi.nlm.nih.gov/pubmed/20452602http://www.ncbi.nlm.nih.gov/pubmed/20452602http://www.ncbi.nlm.nih.gov/pubmed/20452602http://sciencelinks.jp/j-east/article/200613/000020061306A0444654.phphttp://sciencelinks.jp/j-east/article/200613/000020061306A0444654.php



Proteins/Peptides


Development and validation of HPLC-DAD-CAD-MS3 method for qualitative and quantitative standardization of polyphenols in Agrimoniae eupatoriae herba (Ph. Eur).

Granica, S.; Krupa, K.; Kebowska, A.; Kiss, A. K.


2013 Dec

A new application of charged aerosol detection in liquid chromatography for the simultaneous determination of polar and less polar ginsenosides in ginseng products.

Jia, S.; Li, J.; Yunusova, N.; Park, J. H.; Kwon, S. W.; Lee, J.

Phytochem. Anal. 24 (4), 374380.

2013 JulAug

Analysis of terpene lactones in a Ginkgo leaf extract by high-performance liquid chromatography using charged aerosol detection.

Kakigi, Y.; Mochizuki, N.; Icho, T.; Hakamatsuka, T.; Goda, Y.

Biosci., Biotechnol., Biochem. 74 (3), 590594.

2010

Linear aglycones are the substrates for glycosyltransferase DesVII in methymycin biosynthesis: analysis and implications.

Kao, C.; Borisova, S.; Kim, H.; Liu, H.

J. Am. Chem. Soc. 128 (17), 56065607.

2006 May 3

Certification of a pure reference material for the ginsenoside Rg1.

Kim, D.; Chang, J.; Sohn, H.; Cho, B.; Ko, S.; Nho, K.; Jang, D.; Lee, S.

Accredit. Qual. Assur. 15 (2), 8187.

2009 Sep

Optimization of pressurized liquid extraction for spicatoside A in Liriope platyphylla.

Kim, S. H.; Kim, H. K.; Yang, E. S.; Lee, K. Y.; Kim, S. D.; Kim, Y. C.; Sung, S. H.

Sep. Purif. Technol. 71 (2), 168172.

2010

Production of surfactin and iturin by Bacillus licheniformis N1 responsible for plant disease control activity.

Kong, H. G.; Kim, J. C.; Choi, G. J.; Lee, K. Y.; Kim, H. J.; Hwang, E. C.; Moon, B. J.; Lee, S. W.

Plant Pathol. J. 26 (2), 170177.

2010

Photodiode array (PDA) and other detection methods in HPLC of plant metabolites.

Markowski, W.; Waksmundzka-Hajnos, M.

Chapter 13. In High Performance Liquid Chromatography in Phytochemical Analysis, Chromatographic Science Series, Markowski, W., Sherma, J., Eds.; Taylor & Francis Group, LLC: Boca Raton, FL; 331350.

2010 Nov


http://www.ncbi.nlm.nih.gov/pubmed/24001902http://www.ncbi.nlm.nih.gov/pubmed/24001902http://www.ncbi.nlm.nih.gov/pubmed/24001902http://www.ncbi.nlm.nih.gov/pubmed/23390088http://www.ncbi.nlm.nih.gov/pubmed/23390088http://www.ncbi.nlm.nih.gov/pubmed/23390088http://www.ncbi.nlm.nih.gov/pubmed/20208343http://www.ncbi.nlm.nih.gov/pubmed/20208343http://www.ncbi.nlm.nih.gov/pubmed/20208343http://www.ncbi.nlm.nih.gov/pubmed/16637606http://www.ncbi.nlm.nih.gov/pubmed/16637606http://link.springer.com/article/10.1007/s00769-009-0588-6#page-1http://link.springer.com/article/10.1007/s00769-009-0588-6#page-1http://www.sciencedirect.com/science/article/pii/S1383586609004730http://www.sciencedirect.com/science/article/pii/S1383586609004730http://www.google.com/url?sa=t&rct=j&q=&esrc=s&frm=1&source=web&cd=1&ved=0CDAQFjAA&url=http%3A%2F%2Fplantpathologyjournal.org%2Ffolder.php%3Fa%3Ddown%26id%3D77688&ei=R6ZlUqa0Mom-igLI3YDQAw&usg=AFQjCNHUeZ3NuTFdfZBq5GVKDnjAd4j3CA&sig2=0Ggcd6dNTApgHTlgfrFHRwhttp://www.google.com/url?sa=t&rct=j&q=&esrc=s&frm=1&source=web&cd=1&ved=0CDAQFjAA&url=http%3A%2F%2Fplantpathologyjournal.org%2Ffolder.php%3Fa%3Ddown%26id%3D77688&ei=R6ZlUqa0Mom-igLI3YDQAw&usg=AFQjCNHUeZ3NuTFdfZBq5GVKDnjAd4j3CA&sig2=0Ggcd6dNTApgHTlgfrFHRwhttp://www.crcnetbase.com/doi/book/10.1201/b10320http://www.crcnetbase.com/doi/book/10.1201/b10320


High-performance liquid chromatography analysis of plant saponins: An update 2005-2010.

Negi, J. S.; Singh, P.; Pant, G. J.; Rawat, M. S.

Pharmacogn. Rev. 5 (10), 155158.

2011 Jul

Application of high-performance liquid chromatography with charged aerosol detection for universal quantitation of undeclared phosphodiesterase-5 inhibitors in herbal dietary supplements.

Poplawska, M.; Blazewicz, A.; Bukowinska, K.; Fijalek, Z.


2013 Oct

Isolation and analysis of ginseng: advances and challenges. Qi, L.; Wang, C.; Yuan, C. Nat. Prod. Rep. 28 (3), 467495.

2011 Mar

A biosynthetic pathway for BE-7585A, a 2-thiosugar-containing angucycline-type natural product.

Sasaki, E.; Ogasawara, Y.; Liu, H. W.

J. Am. Chem. Soc. 132 (21), 74057417.

2010 Jun 2

Rapid purification method for fumonisin B1 using centrifugal partition chromatography.

Szekeres, A.; Lorntfy, L.; Bencsik, O.; Kecskemti, A.; Szcsi, .; Mesterhzy, .; Vgvlgyi, C.

Food Addit. Contam. 30 (1), 147155.

2013

Performance evaluation of charged aerosol and evaporative light scattering detection for the determination of ginsenosides by LC.

Wang, L.; He, W. S.; Yan, H. X.; Jiang, Y.; Bi, K. S.; Tu, P. F.


2009 Aug

HPLC in natural product analysis: The detection issue. Wolfender, J. L. Planta Med. 75 (07), 719734.

2009 Jun

Simultaneous determination of triterpenoid saponins from pulsatilla koreana using high performance liquid chromatography coupled with a charged aerosol detector (HPLC-CAD).

Yeom, H.; Suh, J. H.; Youm, J. R.; Han, S. B.

Bull. Korean Chem. Soc. 31 (5), 11591164.

2010



Proteins/Peptides


http://www.ncbi.nlm.nih.gov/pubmed/22303089http://www.ncbi.nlm.nih.gov/pubmed/22303089http://www.ncbi.nlm.nih.gov/pubmed/23850939http://www.ncbi.nlm.nih.gov/pubmed/23850939http://www.ncbi.nlm.nih.gov/pubmed/23850939http://www.ncbi.nlm.nih.gov/pubmed/23850939http://www.ncbi.nlm.nih.gov/pubmed/21258738http://www.ncbi.nlm.nih.gov/pubmed/20443562http://www.ncbi.nlm.nih.gov/pubmed/20443562http://www.ncbi.nlm.nih.gov/pubmed/23043634http://www.ncbi.nlm.nih.gov/pubmed/23043634http://link.springer.com/article/10.1365/s10337-009-1192-yhttp://link.springer.com/article/10.1365/s10337-009-1192-yhttp://link.springer.com/article/10.1365/s10337-009-1192-yhttp://www.ncbi.nlm.nih.gov/pubmed/19145552http://hero.epa.gov/?action=reference.details&reference_id=1120226http://hero.epa.gov/?action=reference.details&reference_id=1120226http://hero.epa.gov/?action=reference.details&reference_id=1120226http://hero.epa.gov/?action=reference.details&reference_id=1120226



Proteins/Peptides


Charged aerosol detection in pharmaceutical analysis. Almeling, S.; Ilko, D.; Holzgrabe, U.


2012 Oct

Quantitation of acetol in common pharmaceutical excipients using LCMS.

Beilin, E.; Baker, L. J.; Culbert, P.; Toltl, N. P.


2008 Jan 22

Determination of pancuronium and its impurities in pharmaceutical preparation by LC with charged aerosol detection.

Bazewicz, A.; Fijaek, Z.; Sarna, K.; Warowna-Grzeskiewicz, M.


2010 Jul

Determination of atracurium, cisatracurium and mivacurium with their impurities in pharmaceutical preparations by liquid chromatography with charged aerosol detection.

Bazewicz, A.; Fijaek, Z.; Warowna-Grzeskiewicz, M.; Jadach, M.

J. Chromatogr., A. 1217 (8), 12661272.

2010 Feb 19

Corona-charged aerosol detection in supercritical fluid chromatography for pharmaceutical analysis.

Brunelli, C.; Grecki, T.; Zhao, Y.; Sandra, P.

Anal. Chem. 79 (6), 24722482.

2007 Mar 15

Hydrophilic interaction chromatography with aerosol-based detectors (ELSD, CAD, NQAD) for polar compounds lacking a UV chromophore in an intravenous formulation.

Cintrn, J. M.; Risley, D. S. J. Pharm. Biomed. Anal. 7879, 1418.

2013 May 5

Comprehensive approaches for measurement of active pharmaceutical ingredients, counter-ions, and excipients using HPLC with charged aerosol detection.

Crafts, C.; Bailey, B.; Gamache, P.; Liu, X.; Acworth, I.

Chapter 10. In Applications of Ion Chromatography in the Analysis of Pharmaceutical and Biological Products; Bhattacharyya, L., Rohrer, J. S., Eds.; Wiley: New Jersey, 221236.

2012 Mar

Pharmaceuticals

http://www.ncbi.nlm.nih.gov/pubmed/22487591http://www.ncbi.nlm.nih.gov/pubmed/18054457http://www.ncbi.nlm.nih.gov/pubmed/18054457http://link.springer.com/article/10.1365/s10337-010-1623-9http://link.springer.com/article/10.1365/s10337-010-1623-9http://link.springer.com/article/10.1365/s10337-010-1623-9http://www.ncbi.nlm.nih.gov/pubmed/20036772http://www.ncbi.nlm.nih.gov/pubmed/20036772http://www.ncbi.nlm.nih.gov/pubmed/20036772http://www.ncbi.nlm.nih.gov/pubmed/17302387http://www.ncbi.nlm.nih.gov/pubmed/17302387http://www.ncbi.nlm.nih.gov/pubmed/23434524http://www.ncbi.nlm.nih.gov/pubmed/23434524http://www.ncbi.nlm.nih.gov/pubmed/23434524http://www.wiley.com/WileyCDA/WileyTitle/productCd-0470467096.htmlhttp://www.wiley.com/WileyCDA/WileyTitle/productCd-0470467096.htmlhttp://www.wiley.com/WileyCDA/WileyTitle/productCd-0470467096.html



Proteins/Peptides


Evaluation of methods for the simultaneous analysis of cations and anions using HPLC with charged aerosol detection and a zwitterionic stationary phase.

Crafts, C.; Bailey, B.; Plante, M.; Acworth, I.

J. Chromatogr. Sci. 47 (7), 534539.

2009 Aug

HILIC methods in pharmaceutical analysis. Dejaegher, B.; Heyden, Y. J. Sep. Sci. 33 (67), 698715.

2010 Mar




2008 Nov 4

A charged aerosol detector that reduces vaccine development time.

Fireman, J.; Carter, D.; Wallace, M.

Am. Biotechnol. Lab. 25, 18.

2007

HPLC with charged aerosol detection for pharmaceutical cleaning validation.

Forsatz, B.; Snow, N. LC-GC North America 25 (9), 960.

2007 Sep 1

Squalene emulsions for parenteral vaccine and drug delivery. Fox, C. B. Molecules 14 (9), 32863312.

2009 Sep 1

Monitoring the effects of component structure and source on formulation stability and adjuvant activity of oil-in-water emulsions.

Fox, C. B.; Anderson, R. C.; Dutill, T. S.; Goto, Y.; Reed, S. G.; Vedvick, T. S.

Colloids Surf., B 65 (1), 98105.

2008 Aug 1

Effects on immunogenicity by formulations of emulsion-based adjuvants for malaria vaccines.

Fox, C. B.; Baldwin, S. L.; Vedvick, T. S.; Angov, E.; Reed, S. G.

Clin. Vaccine Immunol. 19 (10), 16331640.

2012 Oct

Obstacles and pitfalls in the PEGylation of therapeutic proteins.

Gaberc-Porekar, V.; Zore, I.; Podobnik, B.; Menart, V.

Curr. Opin. Drug Discovery Dev. 11 (2), 242250.

2008 Mar


Gorecki, T.; Lynen, F.; Szucs, R.; Sandra, P.

Anal. Chem. 78 (9), 31863192.

2006 May 1

Pharmaceuticals

http://www.ncbi.nlm.nih.gov/pubmed/19772722http://www.ncbi.nlm.nih.gov/pubmed/19772722http://www.ncbi.nlm.nih.gov/pubmed/19772722http://www.ncbi.nlm.nih.gov/pubmed/20183826http://www.ncbi.nlm.nih.gov/pubmed/18818041http://www.ncbi.nlm.nih.gov/pubmed/18818041http://www.ncbi.nlm.nih.gov/pubmed/18818041http://www.americanlaboratory.com/913-Technical-Articles/18996-A-Charged-Aerosol-Detector-That-Reduces-Vaccine-Development-Time/http://www.americanlaboratory.com/913-Technical-Articles/18996-A-Charged-Aerosol-Detector-That-Reduces-Vaccine-Development-Time/http://www.chromatographyonline.com/lcgc/article/articleDetail.jsp?id=454549http://www.chromatographyonline.com/lcgc/article/articleDetail.jsp?id=454549http://www.mdpi.com/1420-3049/14/9/3286http://www.ncbi.nlm.nih.gov/pubmed/18440205http://www.ncbi.nlm.nih.gov/pubmed/18440205http://www.ncbi.nlm.nih.gov/pubmed/18440205http://www.ncbi.nlm.nih.gov/pubmed/22896687http://www.ncbi.nlm.nih.gov/pubmed/22896687http://www.ncbi.nlm.nih.gov/pubmed/18283612http://www.ncbi.nlm.nih.gov/pubmed/18283612http://www.ncbi.nlm.nih.gov/pubmed/16643012http://www.ncbi.nlm.nih.gov/pubmed/16643012



Proteins/Peptides


Control of impurities in L-aspartic acid and L-alanine by high-performance liquid chromatography coupled with a corona charged aerosol detector.

Holzgrabe, U.; Nap, C. J.; Almeling, S.

J. Chromatogr., A. 1217 (3), 294301.

2010 Jan 15

Alternatives to amino acid analysis for the purity control of pharmaceutical grade L-alanine.

Holzgrabe, U.; Nap, C. J.; Beyer, T.; Almeling, S.

J. Sep. Sci. 33 (16), 24022410.

2010 Aug

Development of a reversed-phase HPLC impurity method for a UV variable isomeric mixture of a CRF drug substance intermediate with the assistance of Corona CAD.

Huang, Z.; Neverovitch, M.; Lozano, R.; Tattersall, P.; Ruan, J.

J. Pharm. Innov. 6 (2), 115123.

2011 Jun

Determination of inorganic pharmaceutical counterions using hydrophilic interaction chromatography coupled with a Corona CAD detector.

Huang, Z.; Richards, M. A.; Zha, Y.; Francis, R.; Lozano, R.; Ruan, J.


2009 Dec 5

Forced degradation and impurity profiling: Recent trends in analytical perspectives.

Jain, D.; Basniwal, P. K. J. Pharm. Biomed. Anal. 86, 1135.

2013 Jul 31

Non-derivatization method for the determination of gabapentin in pharmaceutical formulations, rat serum and rat urine using high performance liquid chromatography coupled with charged aerosol detection.

Jia, S.; Lee, H.S.; Choi, M.J.; Sung, S.H.; Han, S.B.; Park, J.H.; Hong, S.S.; Kwon, S.W.; Lee, J.

Curr. Anal. Chem. 8 (1), 159167.

2012

Comparison of two aerosol-based detectors for the analysis of gabapentin in pharmaceutical formulations by hydrophilic interaction chromatography.

Jia, S.; Park, J. H.; Lee, J.; Kwon, S. W.

Talanta 85 (5), 23012306. 2011 Oct 15

Linear aglycones are the substrates for glycosyltransferase DesVII in methymycin biosynthesis: analysis and implications.

Kao, C. L.; Borisova, S. A.; Kim, H. J.; Liu, H. W.

J. Am. Chem. Soc. 128 (17), 56065607.

2006 May 3

Ion chromatography coupled to universal detectors for the analysis of pharmaceutically-related anions.

Karu, N.; Hutchinson, J. P.; Dicinoski, G. W.; Hanna-Brown, M.; Haddad, P. R.

Sep. Sci. 4 (14), 1419. 2012

Pharmaceuticals

http://www.ncbi.nlm.nih.gov/pubmed/19954785http://www.ncbi.nlm.nih.gov/pubmed/19954785http://www.ncbi.nlm.nih.gov/pubmed/19954785http://www.ncbi.nlm.nih.gov/pubmed/20549666http://www.ncbi.nlm.nih.gov/pubmed/20549666http://link.springer.com/article/10.1007%2Fs12247-011-9105-7http://link.springer.com/article/10.1007%2Fs12247-011-9105-7http://link.springer.com/article/10.1007%2Fs12247-011-9105-7http://www.ncbi.nlm.nih.gov/pubmed/19616396http://www.ncbi.nlm.nih.gov/pubmed/19616396http://www.ncbi.nlm.nih.gov/pubmed/19616396http://www.ncbi.nlm.nih.gov/pubmed/23969330http://www.ncbi.nlm.nih.gov/pubmed/23969330http://www.eurekaselect.com/75926/articlehttp://www.eurekaselect.com/75926/articlehttp://www.eurekaselect.com/75926/articlehttp://www.eurekaselect.com/75926/articlehttp://www.ncbi.nlm.nih.gov/pubmed/21962646http://www.ncbi.nlm.nih.gov/pubmed/21962646http://www.ncbi.nlm.nih.gov/pubmed/21962646http://www.ncbi.nlm.nih.gov/pubmed/16637606http://www.ncbi.nlm.nih.gov/pubmed/16637606http://www.sepscience.com/Techniques/IC/Articles/1316-/Ion-Chromatography-coupled-to--Universal-Detectors-for-The-Analysis--of-Pharmaceutically-related-Anionshttp://www.sepscience.com/Techniques/IC/Articles/1316-/Ion-Chromatography-coupled-to--Universal-Detectors-for-The-Analysis--of-Pharmaceutically-related-Anions



Proteins/Peptides


Determination of pharmaceutically related compounds by suppressed ion chromatography: IV. Interfacing ion chromatography with universal detectors.

Karu, N.; Hutchinson, J. P.; Dicinoski, G. W.; Hanna-Brown, M.; Srinivasan, K.; Pohl, C. A.; Haddad, P. R.

J. Chromatogr., A. 1253, 4451.

2012 Aug 31

PEGylation of cholecystokinin prolongs its anorectic effect in rats.

Len-Tamariz, F.; Verbaeys, I.; Van Boven, M.; De Cuyper, M.; Buyse, J.; Clynen, E.; Cokelaere, M.

Peptides 28 (5), 10031011.

2007 May

Direct stability-indicating method development and validation for analysis of etidronate disodium using a mixed-mode column and charged aerosol detector.

Liu, X. K.; Fang, J. B.; Cauchon, N.; Zhou, P.


2008 Mar 13

Evaluation of charged aerosol detection (CAD) as a complementary technique for high-throughput LC-MS-UV-ELSD analysis of drug discovery screening libraries.

Loughlin, J.; Phan, H.; Wan, M.; Guo, S.; May, K.; Lin, B.

American Laboratory 39, 24.

2007 Sep

Serial coupling of reversed-phase and hydrophilic interaction liquid chromatography to broaden the elution window for the analysis of pharmaceutical compounds.

Louw, S.; Pereira, A.; Lynen, F.; Hanna-Brown, M.; Sandra, P.

J. Chromatogr., A. 1208 (12), 9094.

2008 Oct 24

Compound purity assessment and impurity testing with Corona CAD.

McCarthy, R.; Gamache, P.; Asa, D.

G.I.T. Laboratory Journal Europe 9, (4), 2627.

2005

Aerosol based detectors for the investigation of phospholipid hydrolysis in a pharmaceutical suspension formulation.

Nair, L. M.; Werling, J. O. J. Pharm. Biomed. Anal. 49 (1), 9599.

2009 Jan 15

Comparison of UV and charged aerosol detection approach in pharmaceutical analysis of statins.

Novkov, L.; Lopz, S. A.; Solichov, D.; Satnsk, D.; Kulichov, B.; Horna, A.; Solich, P.

Talanta 78 (3), 834839. 2009 May 15

Novel MS solutions inspired by MIST. Ramanathan, R.; Josephs, J. L.; Jemal, M.; Arnold, M.; Humphreys, W. G.

Bioanalysis 2 (7), 12911313.

2010 Jul

Pharmaceuticals

http://www.ncbi.nlm.nih.gov/pubmed/22840819http://www.ncbi.nlm.nih.gov/pubmed/22840819http://www.ncbi.nlm.nih.gov/pubmed/22840819http://www.ncbi.nlm.nih.gov/pubmed/17379357http://www.ncbi.nlm.nih.gov/pubmed/17379357http://www.ncbi.nlm.nih.gov/pubmed/18215488http://www.ncbi.nlm.nih.gov/pubmed/18215488http://www.ncbi.nlm.nih.gov/pubmed/18215488http://www.researchgate.net/publication/228510094_Evaluation_of_Charged_Aerosol_Detection_(CAD)_as_a_Complementary_Technique_for_High-Throughput_LC-MS-UV-ELSD_Analysis_of_Drug_Discovery_Screening_http://www.researchgate.net/publication/228510094_Evaluation_of_Charged_Aerosol_Detection_(CAD)_as_a_Complementary_Technique_for_High-Throughput_LC-MS-UV-ELSD_Analysis_of_Drug_Discovery_Screening_http://www.researchgate.net/publication/228510094_Evaluation_of_Charged_Aerosol_Detection_(CAD)_as_a_Complementary_Technique_for_High-Throughput_LC-MS-UV-ELSD_Analysis_of_Drug_Discovery_Screening_http://www.ncbi.nlm.nih.gov/pubmed/18771775http://www.ncbi.nlm.nih.gov/pubmed/18771775http://www.ncbi.nlm.nih.gov/pubmed/18771775http://cat.inist.fr/?aModele=afficheN&cpsidt=17053801http://cat.inist.fr/?aModele=afficheN&cpsidt=17053801http://www.ncbi.nlm.nih.gov/pubmed/19070982http://www.ncbi.nlm.nih.gov/pubmed/19070982http://www.ncbi.nlm.nih.gov/pubmed/19269437http://www.ncbi.nlm.nih.gov/pubmed/19269437http://www.ncbi.nlm.nih.gov/pubmed/21083241



Proteins/Peptides


The effect of composting on the degradation of a veterinary pharmaceutical.

Ramaswamy, J.; Prasher, S. O.; Patel, R. M.; Hussain, S. A.; Barrington, S. F.

Bioresour Technol. 101 (7), 22942299.

2010 Apr

Implementation of charged aerosol detection in routine reversed phase liquid chromatography methods.

Reilly, J.; Everatt, B.; Aldcroft, C. J. Liq. Chromatogr. Relat. Technol. 31 (20), 31323142.

2008 Oct 22

Simultaneous determination of Maillard reaction impurities in memantine tablets using HPLC with charged aerosol detector.

Rystov, L.; Chadwick, R.; Krock, K.; Wang, T.


2011 Dec 15

Comparison of ultraviolet detection, evaporative light scattering detection and charged aerosol detection methods for liquid-chromatographic determination of anti-diabetic drugs.

Shaodong, J.; Lee, W. J.; Ee, J. W.; Park, J. H.; Kwon, S. W.; Lee, J.


2010 Mar 11

Applications of the charged aerosol detector in compound management.

Sinclair, I.; Charles, I. J. Biomol. Screening 14 (5), 531537.

2009 Jun

Charged aerosol detection: Factors for consideration in its use as a generic quantitative detector.

Sinclair, I.; Gallagher, R. Chromatography Today 1 (3), 59.

2008 Jun

Determination of relative response factors of impurities in paclitaxel with high performance liquid chromatography equipped with ultraviolet and charged aerosol detectors.

Sun, P.; Wang, X.; Alquier, L.; Maryanoff, C.

J. Chromatogr., A. 1177 (1), 8791.

2008 Jan 4

Performance evaluation of evaporative light scattering detection and charged aerosol detection in reversed phase liquid chromatography.

Vervoort, N.; Daemen, D.; Trk, G.

J. Chromatogr., A 1189 (12), 92100.

2008 May 2

Neurolipids and the use of a charged aerosol detector. Waraska, J.; Acworth, I. N. American Biotech. Lab. 26 (1), 1213.

2008

HPLC determinations of enantiomeric ratios. Wipf, P.; Werner, S.; Twining, L. A.; Kendall, C.

Chirality 19 (1), 59. 2007 Jan

Pharmaceuticals

http://www.ncbi.nlm.nih.gov/pubmed/19944598http://www.ncbi.nlm.nih.gov/pubmed/19944598http://www.tandfonline.com/doi/abs/10.1080/10826070802480081http://www.tandfonline.com/doi/abs/10.1080/10826070802480081http://www.ncbi.nlm.nih.gov/pubmed/21852059http://www.ncbi.nlm.nih.gov/pubmed/21852059http://www.ncbi.nlm.nih.gov/pubmed/20004074http://www.ncbi.nlm.nih.gov/pubmed/20004074http://www.ncbi.nlm.nih.gov/pubmed/20004074http://www.ncbi.nlm.nih.gov/pubmed/20004074http://www.ncbi.nlm.nih.gov/pubmed/19483147http://www.ncbi.nlm.nih.gov/pubmed/19483147http://www.chromatographytoday.com/article_read/524/http://www.chromatographytoday.com/article_read/524/http://www.ncbi.nlm.nih.gov/pubmed/18067905http://www.ncbi.nlm.nih.gov/pubmed/18067905http://www.ncbi.nlm.nih.gov/pubmed/18067905http://www.ncbi.nlm.nih.gov/pubmed/18054946http://www.ncbi.nlm.nih.gov/pubmed/18054946http://www.ncbi.nlm.nih.gov/pubmed/18054946http://new.med.wanfangdata.com.cn/Paper/Detail?id=PeriodicalPaper_JJ024318680http://www.ncbi.nlm.nih.gov/pubmed/17089337


Biosynthesis of fosfomycin, re-examination and re-confirmation of a unique Fe(II)- and NAD(P)H-dependent epoxidation reaction.

Yan, F.; Munos, J. W.; Liu, P.; Liu, H. W.

Biochemistry 45 (38), 1147311481.

2006 Sep 26

A new approach to threshold evaluation and quantitation of unknown extractables and leachables using HPLC/CAD

Yu, X., Zdravkovic, S., Wood, D.; Li, C., Cheng, Y.; Ding, X.

Drug Delivery Technol. 9 (3), 5055.

2009

Genotoxic impurities: A quantitative approach. Yuabova, Z. Y.; Holschlag, D. R.; Rodriguez, S. A.; Qin, C.; Papov, V. V.; Qiu, F.; McCaffrey, J. F.; Norwood, D. L.

J. Liq. Chromatogr. Relat. Technol. 31, 23182330.

2008 Aug 7

Advances in HPLC detectiontowards universal detection. Zhang, B.; Li, X.; Yan, B. Anal. Bioanal. Chem. 390 (1), 299301.

2008 Jan

Analysis of pharmaceutical impurities using multi-heart cutting 2D LC coupled with UV-charged aerosol MS detection.

Zhang, K.; Li, Y.; Tsang, M.; Chetwyn, N. P.

J. Sep. Sci. 36 (18), 29862992.

2013 Sep



Proteins/Peptides

Pharmaceuticals

http://www.ncbi.nlm.nih.gov/pubmed/16981707http://www.ncbi.nlm.nih.gov/pubmed/16981707http://www.ncbi.nlm.nih.gov/pubmed/16981707http://www.drug-dev.com/uploads/public/images/media/PublicationsIssue/March 2009.pdfhttp://www.drug-dev.com/uploads/public/images/media/PublicationsIssue/March 2009.pdfhttp://www.tandfonline.com/doi/abs/10.1080/10826070802281745?journalCode=ljlc20#previewhttp://www.ncbi.nlm.nih.gov/pubmed/17924099http://www.ncbi.nlm.nih.gov/pubmed/23821312http://www.ncbi.nlm.nih.gov/pubmed/23821312



Proteins/Peptides


Quantitation of acetol in common pharmaceutical excipients using LCMS.

Beilin, E.; Baker, L. J.; Culbert, P.; Toltl, N. P.


2008 Jan 22

Investigating the stability of the nonionic surfactants tocopheryl polyethylene glycol succinate and sucrose laurate by HPLC-MS, DAD, and CAD.

Christiansen, A.; Backensfeld, T.; Khn, S.; Weitschies, W.

J. Pharm. Sci. 100 (5), 17731782.

2011 May

Stability of the non-ionic surfactant polysorbate 80 investigated by HPLC-MS and charged aerosol detector.


Pharmazie 66 (9), 666671. 2011 Sep

Investigating the stability of the nonionic surfactants tocopheryl polyethylene glycol succinate and sucrose laurate by HPLCMS, DAD, and CAD.


J. Pharm. Sci. 100 (5), 17731782.

2011 May

Fast and sensitive determination of Polysorbate 80 in solutions containing proteins.

Fekete, S.; Ganzler, K.; Fekete, J. J. Pharm. Biomed. Anal. 52 (5), 6729.

2010 Sep 5

HPLC with charged aerosol detection for the measurement of different non-ionic surfactants.

Fukushima, K.; Matsumoto, T.; Hashiguchi, K.; Senda, M.; Carreiro, D.; Asa, D.; et al.


2006

Characterization of hydroxypropylmethylcellulose (HPMC) using comprehensive two-dimensional liquid chromatography.

Greiderer, A.; Steeneken, L.; Aalbers, T.; Viv-Truyols, G.; Schoenmakers, P.

J. Chromatogr., A. 1218 (34), 57875793.

2011 Aug 26

Size exclusion chromatography with Corona charged aerosol detector for the analysis of polyethylene glycol polymer.

Kou, D.; Manius, G.; Zhan, S.; Chokshi, H. P.

J. Chromatogr., A. 1216 (28), 54245428.

2009 Jul 10

Analysis of polysorbate 80 using fast HPLC and charged aerosol detection.

Lobback, C.; Backensfeild, T.; Funke, A.; Weltschies, W.

Pharm. Technol. 34 (5), 48. 2010 May

Quantitative determination of nonionic surfactants with CAD. Lobback, C.; Backensfeld, T.; Funke, A.; Weitschies, W.

Chromatography Techniques, 18.

2007 Nov

Quantitative determination of nonionic surfactants with CAD. Lobback, C.; Backensfield, T.; Funke, A.; Weitschies, W.

Drug Discovery Dev. 10 (11, special section), 18.

2007 Nov

Polymers/Surfactants

http://www.ncbi.nlm.nih.gov/pubmed/18054457http://www.ncbi.nlm.nih.gov/pubmed/18054457http://www.ncbi.nlm.nih.gov/pubmed/21374613http://www.ncbi.nlm.nih.gov/pubmed/21374613http://www.ncbi.nlm.nih.gov/pubmed/21374613http://www.ncbi.nlm.nih.gov/pubmed/22026121http://www.ncbi.nlm.nih.gov/pubmed/22026121http://www.ncbi.nlm.nih.gov/pubmed/21374613http://www.ncbi.nlm.nih.gov/pubmed/21374613http://www.ncbi.nlm.nih.gov/pubmed/21374613http://www.ncbi.nlm.nih.gov/pubmed/20307948http://www.ncbi.nlm.nih.gov/pubmed/20307948http://sciencelinks.jp/j-east/article/200624/000020062406A0875441.phphttp://sciencelinks.jp/j-east/article/200624/000020062406A0875441.phphttp://www.ncbi.nlm.nih.gov/pubmed/21777918http://www.ncbi.nlm.nih.gov/pubmed/21777918http://www.ncbi.nlm.nih.gov/pubmed/19501366http://www.ncbi.nlm.nih.gov/pubmed/19501366http://connection.ebscohost.com/c/articles/50744817/analysis-polysorbate-80-using-fast-hplc-charged-aerosol-detectionhttp://connection.ebscohost.com/c/articles/50744817/analysis-polysorbate-80-using-fast-hplc-charged-aerosol-detectionhttp://www.chromatographytechniques.com/http://connection.ebscohost.com/c/articles/27492419/quantitative-determination-nonionic-surfactants-cad


Analysis of quaternary ammonium and phosphonium ionic liquids by reversed-phase high performance liquid chromatography with charged aerosol detection and unified calibration.

Stojanovic, A.; Lmmerhofer, M.; Kogelnig, D.; Schiesel, S.; Sturm, M.; Galanski, M.; Krachler, R.; Keppler, B. K.; Lindner, W.

J. Chromatogr., A 1209 (12), 179187.

2008 Oct 31

Quantitative comparison of a corona-charged aerosol detector and an evaporative light-scattering detector for the analysis of a synthetic polymer by supercritical fluid chromatography.

Takahashi, K.; Kinugasa, S.; Senda, M.; Kimizuka, K.; Fukushima, K.; Matsumoto, T.; Shibata, Y.; Christensen, J.

J. Chromatogr., A. 1193 (12), 151155.

2008 Jun 6

SEC assay for polyvinylsulfonic impurities in 2-(N-morpholino) ethanesulfonic acid using a charged aerosol detector.

Zhang, T.; Hewitt, D.; Kao, Y. H. Chromatographia 72 (12), 145149.

2010 Jul



Proteins/Peptides

Polymers/Surfactants

http://www.ncbi.nlm.nih.gov/pubmed/18805540http://www.ncbi.nlm.nih.gov/pubmed/18805540http://www.ncbi.nlm.nih.gov/pubmed/18805540http://www.ncbi.nlm.nih.gov/pubmed/18805540http://www.ncbi.nlm.nih.gov/pubmed/18439611http://www.ncbi.nlm.nih.gov/pubmed/18439611http://www.ncbi.nlm.nih.gov/pubmed/18439611http://link.springer.com/article/10.1365%2Fs10337-010-1626-6http://link.springer.com/article/10.1365%2Fs10337-010-1626-6



Proteins/Peptides


Evaluation of charged aerosol detector for purity assessment of protein.

Wang, R.; Wang, X.; Paulino, J.; Alquier, L.

J. Chromatogr., A. 1283, 116121.

2013 Mar 29

Proteins/Peptides

http://www.ncbi.nlm.nih.gov/pubmed/23433488http://www.ncbi.nlm.nih.gov/pubmed/23433488

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