Halogen compoundsQ 0090 DOI: 10.1002/chin.201237050

Copper-Catalyzed Trifluoromethylation of Allylsilanes. — The reaction is per-formed using Togni's reagent (II) and CuI as catalyst. 2-Substituted allylsilanes afford desilylated products, whereas allylsilanes without a substituent in the 2-position give vinylsilane derivatives. An alternative route is found for branched trifluoromethylated alkenes like (V). The treatment of epoxide (X) with alkyllithium compounds provides unexpectedly the desired α-alkylated products in high yields. In addition, the utility of the products is demonstrated by further transformations. — (SHIMIZU, R.; EGAMI, H.; HAMASHIMA, Y.; SODEOKA*, M.; Angew. Chem., Int. Ed. 51 (2012) 19, 4577-4580, http://dx.doi.org/10.1002/anie.201201095 ; RIKEN Adv. Sci. Inst., Wako, Saitama 351-01, Japan; Eng.) — Klein

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ChemInform 2012, 43, issue 37 © 2012 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim