cheminform abstract: novel, potent and selective chimeric fxa inhibitors featuring hydrophobic...

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2001 amino acids, peptides amino acids, peptides U 0400 03 - 173 Novel, Potent and Selective Chimeric FXa Inhibitors Featuring Hydrophobic P 1 -Ketoamide Moieties. A novel potent family (I) of FXa inhibitors is created with (Ic) as the most potent derivative. — (SEM- PLE, J. EDWARD; LEVY, ODILE E.; MINAMI, NATHANIEL K.; OWENS, TIMOTHY D.; SIEV, DANIEL V.; Bioorg. Med. Chem. Lett. 10 (2000) 20, 2305-2309; Dep. Med. Chem., Corvas Int., Inc., San Diego, CA 92121, USA; EN) 1

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Page 1: ChemInform Abstract: Novel, Potent and Selective Chimeric FXa Inhibitors Featuring Hydrophobic P1-Ketoamide Moieties

2001 amino acids, peptides

amino acids, peptidesU 0400

03 - 173Novel, Potent and Selective Chimeric FXa Inhibitors FeaturingHydrophobic P1-Ketoamide Moieties. — A novel potent family (I) ofFXa inhibitors is created with (Ic) as the most potent derivative. — (SEM-PLE, J. EDWARD; LEVY, ODILE E.; MINAMI, NATHANIEL K.; OWENS,TIMOTHY D.; SIEV, DANIEL V.; Bioorg. Med. Chem. Lett. 10 (2000) 20,2305-2309; Dep. Med. Chem., Corvas Int., Inc., San Diego, CA 92121, USA; EN)

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