cheminform abstract: synthesis and vesicle formation of novel pseudoglyceryl dimeric lipids....

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1998 lipids lipids U 0750 16 - 236 Synthesis and Vesicle Formation of Novel Pseudoglyceryl Dimeric Lipids. Evidence of Formation of Widely Different Membrane Organizations with Exceptional Thermotropic Properties. New bis-cationic dimeric lipids (VII) (8 examples) are synthesized which form vesicles by dispersion in aqueous solutions. Thermal, spectroscopic, DLS and X-ray studies reveal the formation of three different kinds of membranous aggregates depending on the chain length of the alkanediyl spacer Y. (BHATTACHARYA, S.; DE, S.; GEORGE, S. K.; Chem. Commun. (Cam- bridge) (1997) 23, 2287-2288; Dep. Org. Chem., Indian Inst. Sci., Bangalore 560 012, India; EN) 1

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Page 1: ChemInform Abstract: Synthesis and Vesicle Formation of Novel Pseudoglyceryl Dimeric Lipids. Evidence of Formation of Widely Different Membrane Organizations with Exceptional Thermotropic

1998 lipids

lipidsU 0750

16 - 236Synthesis and Vesicle Formation of Novel Pseudoglyceryl DimericLipids. Evidence of Formation of Widely Different MembraneOrganizations with Exceptional Thermotropic Properties. — Newbis-cationic dimeric lipids (VII) (8 examples) are synthesized which formvesicles by dispersion in aqueous solutions. Thermal, spectroscopic, DLS andX-ray studies reveal the formation of three different kinds of membranousaggregates depending on the chain length of the alkanediyl spacer Y. —(BHATTACHARYA, S.; DE, S.; GEORGE, S. K.; Chem. Commun. (Cam-bridge) (1997) 23, 2287-2288; Dep. Org. Chem., Indian Inst. Sci., Bangalore560 012, India; EN)

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