cheminform abstract: the synthesis of oxa-analogues and homologues of naturally occurring polyamines
TRANSCRIPT
1998 other bioactive products
other bioactive productsU 1300
42 - 248The Synthesis of Oxa-Analogues and Homologues of NaturallyOccurring Polyamines. — The synthesis of polyamine oxa-analogues andhomologues (IX) with the aminooxy group located within the polyamine chainis reported. The preparations proceed via the Fmoc-deprotection of compounds(III) involving an unusual rearrangement to the N-aminooxy derivatives (IV)and the alkylation of the N-sulfonylated aminooxy compound (VI). Naturalpolyamines are ubiquitous biomolecules in living cells. — (LIN, P. K. T.;KUKSA, V. A.; MAGUIRE, N. M.; Synthesis (1998) 6, 859-866; Sch. Appl.Sci., Robert Gordon Univ., Aberdeen AB25 1HG, UK; EN)
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