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    Chemotherapy Drug Possible Side Effects(Not all side effects are listed. Some of

    those listed may be short-term sideeffects; others are long-term side

    effects.)

    Carboplatin (Paraplatin)

    usually givenintravenously (IV)

    used for cancers ofthe ovary, head and neck,and lung

    decrease in blood cell counts hair loss (reversible)

    confusion

    nausea, vomiting, and/ordiarrhea (usually a short-term sideeffect occurring the first 24 to 72 hoursfollowing treatment)

    cisplatin(Platinol, Platinol-AQ)

    usually givenintravenously (IV)

    used for cancers ofthe bladder, ovary, andtesticles

    decrease in blood cell counts

    allergic reaction, including arash and/or labored breathing

    nausea and vomiting thatusually occurs for 24 hours or longer

    ringing in ears and hearing loss

    fluctuations in bloodelectrolytes

    kidney damage

    cyclophosphamide(Cytoxan, Neosar)

    can be givenintravenously (IV) or orally

    used for lymphoma,breast cancer, and ovariancarcinoma

    decrease in blood cell counts

    nausea, vomiting, abdominalpain

    decreased appetite

    hair loss (reversible)

    bladder damage

    fertility impairment

    lung or heart damage (with highdoses)

    secondary malignancies (rare)

    docetaxel(Taxotere)

    given intravenously(IV)

    used for breastcancer, lung, and prostate

    decrease in blood cell counts

    nausea, vomiting, abdominalpain

    diarrhea

    decreased appetite

    hair thinning

    rash

    numbness and tingling in handsand feet

    doxorubicin(Adriamycin)

    given intravenously(IV)

    used for breastcancer, lymphoma, and

    decrease in blood cell counts

    mouth ulcers

    hair loss (reversible)

    nausea and vomiting

    heart damage

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    multiple myeloma

    Erlotinib (Tarceva)

    given orally

    used for non smallcell lung cancer

    rash and other skin changes

    diarrhea

    etoposide(VePesid)

    can be givenintravenously (IV) or orally

    used for cancers ofthe lung, testicles,

    leukemia, and lymphoma

    decrease in blood cell counts

    hair loss (reversible)

    nausea and vomiting

    allergic reaction

    mouth ulcers

    low blood pressure (duringadministration)

    decreased appetite

    diarrhea and abdominal pain

    bronchospasm

    flu-like symptoms

    fluorouracil(5-FU)

    given intravenously(IV)

    used for cancers of

    the colon, breast, stomach,and head and neck

    decrease in blood cell counts

    diarrhea

    mouth ulcers

    photosensitivity

    dry skin

    gemcitabine(Gemzar)

    given intravenously(IV)

    used for cancers ofthe pancreas, breast, ovary,and lung

    decrease in blood cell counts

    nausea and vomiting

    fever and flu-like symptoms

    rash

    imatinib mesylate(Gleevec)

    given orally

    used for chronicmyelogenous leukemia(CML) and gastrointestinalstromal tumor (GIST)

    nausea and vomiting

    fluid retention (swelling aroundankles, eyes)

    muscle cramps

    diarrhea

    gastrointestinal bleeding

    rash

    irinotecan(Camptosar)

    given intravenously

    decrease in blood cell counts

    diarrhea

    hair loss (reversible)

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    (IV)

    used for cancers ofthe colon and rectum

    methotrexate(Folex, Mexate, Amethopterin)

    may be givenintravenously (IV),intrathecally (into the spinalcolumn), or orally

    used for cancers ofthe breast, lung, blood,bone, and lymph system

    decrease in blood cell counts

    nausea and vomiting

    mouth ulcers

    skin rashes and photosensitivity

    dizziness, headache, ordrowsiness

    kidney damage (with a high-dose therapy)

    liver damage

    hair loss (reversible)

    seizurespaclitaxel(Taxol, Abraxane)

    given intravenously(IV)

    used with cancers ofthe breast, ovary, and lung

    decrease in blood cell counts

    allergic reaction

    nausea and vomiting

    loss of appetite

    change in taste

    thin or brittle hair

    joint pain (short term)

    numbness or tingling in thefingers or toes

    sorafinib(Nexavar)

    given orally

    used for advancedkidney cancer

    high blood pressure (during firstfew weeks of treatment)

    rash, other skin changes

    diarrhea

    fatigue

    hair loss

    nausea and vomiting

    sunitinib(Sutent)

    given orally

    used forgastrointestinal stromaltumor (GIST) and kidneycancer

    diarrhea

    nausea and vomiting

    mouth ulcers

    upset stomach skin changes, including skindiscoloration and rash

    fatigue

    high blood pressure

    bleeding

    swelling

    taste disturbance

    topotecan(Hycamtin)

    given intravenously

    decrease in blood cell counts

    diarrhea

    hair loss (reversible)

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    (IV)

    used for cancers ofthe ovary and lung

    nausea and vomiting

    vincristine(Oncovin, Vincasar PFS)

    usually givenintravenously (IV)

    used for leukemiaand lymphoma

    numbness or tingling in thefingers or toes

    weakness

    loss of reflexes

    jaw pain

    hair loss (reversible)

    constipation or abdominalcramping

    1.nurse will assure that a full history and

    physical assessment is completed

    2. looks at the patient's laboratory results from

    blood that has been drawn for anything

    abnormal to be reported to the oncologist

    3.Confers with the oncologist to be sure that

    the patient has a full understanding of the

    risks and benefits to treatment suggestsCancer Medicine. An oncology nurse is

    focused on the patient's well being both

    physical and emotional.

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    4. explain what chemotherapy treatment is and

    how it works in general terms

    5. Gives the patient more specific information

    about the drugs prescribed, their actions and

    side-effects, and how to manage any side-

    effects

    6. Discuses the importance of avoiding people

    with cough, and obvious infections

    7. It is important for patients to maintain a good

    diet during treatment so nutrition is also

    discussed.

    8.closely monitored during the administration of

    chemotherapy and an oncology nurse is aware

    of the adverse reactions to look for during this

    time and the proper action

    9. Provide safe, competent, and ethical care

    to patients in all practice settings.

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    10. Teach the patient and family how to

    manage these side effects when they are at

    home. The patient and family must also learn

    what symptoms are considered an emergency