CHEMOTHERAPY NURSES ROLE

Mrs. Karuna Laggeri

CLASSIFICATION OF CHEMOTHERAPY DRUGS

Alkylating Agents

Aniti - Metabolites

Micro tubule inhibitors

Anti –tumor antibiotics

Topoisomerase inhibitor

Cyclophosphamide

Ifosphamide

CarboplatinCisplatin

ChlorambucilMelphalanCarmusstine

Oxaliplatin

Temzolamide

5-fluorouracil

CapecitabineGemcitabine

MethotrexateMercaptopurineCytosine arabinoside

VincristineVindesineVinblastine

TaxanesPaclitaxeldocetaxel

Anthracyclines DaunorbicinDoxorubicinEpirubicinMitoxantrone

Bleomycin

Lrinotecan topotecan

CELL CYCLE

CHEMOTHERAPY DRUGS

TARGETED THERAPY( BIOTHERAPY)

Drugs which identify and kills only cells of intrest

Eg: Monocolonal anibodiestrastuxumab in breast cancer

INDICATION FOR CHEMOTHERAPY

Neoadjuvant chemotherapy Induction chemotherapy

Induction chemotherapy consolidation chemotherapy(Anterior chemotherapy) maintenance chemotherapy Adjuvant chemotherapy Maintenance chemotherapy Palliative chemotherapy

cancer

Solid organ malignancie

s

Hematological malignancies

PREPARATION OF DRUGSEquipment types

Bio hazard safety cabinet

Class -I

Class-II&III

Laminar flow cabinet

Fumes Hood

LAMINAR AIR FLOW

LAMINAR AIR FLOW Functioning Purposes Spillage management Certification Do & Don’ts Cleaning and disinfection

GOAL FOR CHEMOTHERAPY Curative Control palliative

ROUTES OF ADMINISTRATION

Oral Subcutaneous/ IM Intravenous Intra thecal Intra vesical Intra peritoneal

ADMINISTRATION

Intra venous types

central

PICC TunneledEg: Hickman

catheter

Non-Tunneled

Eg: IJVImplantable port

peripheral

INTERNAL JUGULAR VEIN

PICC LINE

HICKMAN CATHETER

PORT

INTRA THECAL

INTRA VESICLE CHEMOTHERAPY

INTRA PERITONEAL CHEMOTHERAPY

MAINTENANCE AND CARE OF CATHETER

Accessing Central Venous Catheters Blood Draws from Central Venous

Catheters Flushing technique Changing Catheter Site Dressing

COMPLICATIONS Pneumothorax Heamatoma Heamorrage Injury to artery& surrounding structure Blood stream infection Catheter occlusion Thrombolic occlusion Embolism

SIDE EFFECTS OF CHEMOTHERAPY

Fatigue Nausea & vomiting Diarrhea Alopesia Stomatitis Loss of appetite Leukopenia Memory loss Osteoporosis

THANK YOU