childhood overweight childhood overweight and type 2 diabetes

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Childhood Overweight Childhood Overweight and Type 2 Diabetes and Type 2 Diabetes Turning the Titanic and other Turning the Titanic and other Sisyphean tasks Sisyphean tasks Terry Raymer MD, CDE Alaska Native Diabetes Program [email protected]

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Page 1: Childhood Overweight Childhood Overweight and Type 2 Diabetes

Childhood Overweight Childhood Overweight and Type 2 Diabetesand Type 2 Diabetes

Turning the Titanic and other Turning the Titanic and other Sisyphean tasksSisyphean tasks

Terry Raymer MD, CDEAlaska Native Diabetes Program

[email protected]

Page 2: Childhood Overweight Childhood Overweight and Type 2 Diabetes

Overweight in ChildhoodOverweight in Childhood• Brief overview of epidemiology and etiology

childhood • Evaluation of overweight in children • Medical Consequences • Management recommendations and

communication with families regarding overweight in childhood & case study

• Briefly (if time permits): roles of society – Community and Schools

Page 3: Childhood Overweight Childhood Overweight and Type 2 Diabetes

Source: Behavioral Risk Factor Surveil lance System, CDC.

19961991

2003

Obesity Trends* Among U.S. AdultsBRFSS, 1991, 1996, 2003

(*BMI ≥30, or about 30 lbs overweight for 5’4” person)

No Data <10% 10%–14% 15%–19% 20%–24% ¡ 25%

“the average weight gain among subjects (20-40 years old) in the population is 1.8 to 2.0 pounds/year.”Science. 299:7;853-855 (2003)

Page 4: Childhood Overweight Childhood Overweight and Type 2 Diabetes

Prevalence of Overweight Among U.S. Prevalence of Overweight Among U.S. Children and Adolescents Ages 6Children and Adolescents Ages 6--19 Years19 Years

45

4

67

5

11 11

15.8 16.1

02468

1012141618

Perc

ent

1963-70 1971-74 1976-80 1988-94 1999-02

6-11 Years 12-19 Years

3 FoldIncrease

SOURCE: CDC/NCHS, NHES and NHANESSOURCE: CDC/NCHS, NHES and NHANES

Page 5: Childhood Overweight Childhood Overweight and Type 2 Diabetes

ANMC Overweight Prevalence Report 2004ANMC Overweight Prevalence Report 2004--20072007

0

10

20

30

40

50

60

70

80

2-4 5-14 15-19 20-24 25-44 45-64 65-74

Perc

ent

BMI over 25 BMI over 30 CombinedRPMS DataBMI is for adult population, for ages 2-19…

Page 6: Childhood Overweight Childhood Overweight and Type 2 Diabetes

Defining overweight in ChildrenDefining overweight in Children

• Ages 2-19: 'At Risk for Overweight' is defined as BMI >=85th% but <95th%

• 'Overweight' is defined as BMI >= 95th%• National Center for Health Statistics in

collaboration with the National Center for Chronic Disease Prevention and Health Promotion (2000).

Page 7: Childhood Overweight Childhood Overweight and Type 2 Diabetes

Percentage of Overweight Children and Percentage of Overweight Children and Youth who become overweight AdultsYouth who become overweight Adults

Preventive Medicine 1993; Vol. 22:pp. 167-177Arch Pediatr Adolesc Med Vol. 158 May 2004 pp. 449-452

10

3550

80

0102030405060708090

100Pe

rcen

tage

Infan

tsPres

choo

lSch

ool A

geAdole

scent

Page 8: Childhood Overweight Childhood Overweight and Type 2 Diabetes

Pima IndiansPima Indians Current Prevalence of Type 2 Current Prevalence of Type 2

Diabetes in ChildrenDiabetes in Children10-14 years 22.3/1000

1515--19 years19 years 50.9/100050.9/1000

Prevalence for all American Indian children 4.5/1000

Prevalence for all 0 – 19 y/o children in US 1.7/1000

Page 9: Childhood Overweight Childhood Overweight and Type 2 Diabetes

Altered Dietary Intake

Decreased Physical Activity

Increased Sedentary Behaviors

Parenting Styles

Gestational Diabetes

Childhood Overweight Behavioral Childhood Overweight Behavioral Risk FactorsRisk Factors

Genes are not destiny

Page 10: Childhood Overweight Childhood Overweight and Type 2 Diabetes

A small behavior change over time A small behavior change over time can prevent some weight problems.can prevent some weight problems.

Energy Input vs Energy Output

2% Error Leads to Overweight125 kj /day or 15 Minutes of Play

Instead of TelevisionMichael Goran , Am J Clin Nutr 1999;70

Page 11: Childhood Overweight Childhood Overweight and Type 2 Diabetes

Infant & Toddler OverweightInfant & Toddler Overweight Behavioral Risk FactorsBehavioral Risk Factors

• Breastfeeding rates at 12 months of age are 7%• 17% of infants consume juice before 6 months• 10% of infants consume French fries and soda

before 12 months of age• WIC toddlers consume more 100% juice and

less whole fruit than non-WIC toddlers• WIC toddlers consume 40% more calories than

their energy requirements

Pediatrics October 2004, Vol 114,No. 4 pp. 1146-1173Feeding Infants and Toddlers Survey (FITS) 2004

Page 12: Childhood Overweight Childhood Overweight and Type 2 Diabetes

Billboard on the edge of the Navajo ReservationCourtesy of Tim Gilbert/ANTHC

Why pick on soda?Why pick on soda?

Page 13: Childhood Overweight Childhood Overweight and Type 2 Diabetes

Clear Evidence of Negative effectsClear Evidence of Negative effects• Children’s Hospital in Boston

– Increased consumption definitively linked to weight, increased calories (~300 a day)

• HFCS (sweetener) may contribute to the development of diabetes, particularly in children due to “carbonyl” formation

• Higher insulin resistance and fasting blood levels of insulin even in healthy adults

• Evidence that “diet sodas” are not protective

Page 14: Childhood Overweight Childhood Overweight and Type 2 Diabetes

Childhood OverweightChildhood Overweight Behavioral Risk FactorsBehavioral Risk Factors

• The average consumption of soft drinks by 12- 19 year olds is over 20 ounces per day

• 80% of 5th, 7th and 9th graders in California fail to meet the minimum fitness standards.

• More than 25% of children in CA reported averaging > 4 hours of TV watching per day

• In California, of 7th, 9th and 11th graders surveyed less than half reported eating fruits or vegetables at least once per day in past week.

Page 15: Childhood Overweight Childhood Overweight and Type 2 Diabetes

Fitness and Academic PerformanceFitness and Academic Performance2001 Grade 7 SAT 9 and Physical Fitness

California Department of Education 12/10/02http://www.cde.ca.gov/news/releases2002/rel37.asp

26283132 3436

4144

5054

6066

0

10

20

30

40

50

60

70

1 2 3 4 5 6

ReadingMath

Number of Fitness Standards Achieved

SAT

9 Pe

rcen

tile

Page 16: Childhood Overweight Childhood Overweight and Type 2 Diabetes

Determining the BMIDetermining the BMI• (First you gotta) Measure BMI Annually• Measure BMI at Well Child Care Visits

2-18 years (hint – plot on growth chart)• BMI (English):[ weight (lb) ÷ height (in)

÷ height (in) ] x 703• BMI (metric):[ weight (kg) ÷ height (cm)

÷ height (cm) ] x 10,000• Calculation Tools: www.cdc.gov/ and

www.nhlbisupport.com/bmi/

Page 17: Childhood Overweight Childhood Overweight and Type 2 Diabetes

Determine the DiagnosisDetermine the Diagnosis

Make a weight diagnosis using BMI percentile for age:

• < 5%-ile Underweight• 5-84%-ile: “Healthy Weight”• 85-94%-ile: “at risk for overweight”• > 95%-ile: “Overweight”

Page 18: Childhood Overweight Childhood Overweight and Type 2 Diabetes

Measurement example:

Age=3 y 3 wks

Height=100.8 cm (39.7 in)

Weight=18.6 kg (41 lb)

BMI=18.3

BMI-for-age= >95th%-ile

Boys: 2 to 20 years

BMI BMI

BMI BMI

“Overweight”

Page 19: Childhood Overweight Childhood Overweight and Type 2 Diabetes

Boys: 2 to 20 years

BMI BMI

BMIBMI

BMI

Shape of BMI-for-Age Growth Curve: “Adiposity”

Rebound

• Risk factor for Adult overweight

• Linked to Parental weight

• A Key Intervention AgeExample: Early AR

Age (mos) BMI26 18.232 17.438 18.541 18.7

Page 20: Childhood Overweight Childhood Overweight and Type 2 Diabetes

Conveying the DiagnosisConveying the Diagnosis

For Patient Communication...• Weight or Excess Weight• Body Mass Index (BMI)• Emphasize weight “stabilization”• Focus on healthy habits, not weight loss• Risk for Diabetes & Heart Disease• Better to assign risk, non-pejorative terms

Page 21: Childhood Overweight Childhood Overweight and Type 2 Diabetes

Childhood Overweight Medical Childhood Overweight Medical Assessment: Medical HistoryAssessment: Medical History

• Developmental delay (Genetic disorders)• Poor linear growth (Hypothyroidism, Cushing’s,

Prader-Willi syndrome)• Headaches (Pseudotumor cerebri)• Daytime somnolence (Sleep apnea, hypoventilation)• Nighttime breathing difficulty (Sleep apnea)• Abdominal pain (Gall bladder disease)• Hip or knee pain (Slipped capital femoral epiphysis)• Oligomenorrhea or amenorrhea (Polycystic ovary

syndrome)

Page 22: Childhood Overweight Childhood Overweight and Type 2 Diabetes

Medical Assessment: Medical Assessment: Family HistoryFamily History

• Overweight• Hypertension• Type 2 Diabetes• Dyslipidemia• Cardiovascular disease• Gall bladder disease

Page 23: Childhood Overweight Childhood Overweight and Type 2 Diabetes

Medical Assessment: ExamMedical Assessment: Exam• Height, weight, Blood pressure and BMI• Truncal obesity (Risk of cardiovascular

disease; Cushing’s syndrome)• Acanthosis nigricans (Type 2 DM, insulin

resistance)• Hirsutism (Polycystic ovary syndrome;

Cushing’s syndrome)• Tonsils (Sleep apnea)• Limited hip range of motion (Slipped

capital femoral epiphysis)

Page 24: Childhood Overweight Childhood Overweight and Type 2 Diabetes

AcanthosisAcanthosis

NigricansNigricans

on the Neckon the Neck

Page 25: Childhood Overweight Childhood Overweight and Type 2 Diabetes

Acanthosis NigricansAcanthosis Nigricans

Page 26: Childhood Overweight Childhood Overweight and Type 2 Diabetes

Laboratory AssessmentLaboratory Assessment• BMI 85-94%-ile Without Risk Factors

– Fasting Lipid Profile + Insulin? • BMI 85-94%-ile Age 10 Years or puberty & Older

With Risk Factors Every 2 Years– Fasting Lipid Profile– ALT and AST– Fasting Glucose

• BMI >= 95%ile Age 10 Years & Older Every 2 Years– Fasting Lipid Profile– ALT and AST– Fasting Glucose– Other Tests as Indicated by Health Risks

Page 27: Childhood Overweight Childhood Overweight and Type 2 Diabetes

* Diabetes Care, volume 31, Supplement 1; January 2008: S14

TestingTesting for Diabetes in Kids*for Diabetes in Kids*

• Asymptomatic, age 10 or puberty with BMI > 85%-ile with any 2 of the following:– Family History: type 2 DM in a 1st or 2nd

degree relative– Ethnic Group: Native American, African

American, Hispanic, Asian/Pacific Islander– Signs of Insulin Resistance: acanthosis

nigricans, hypertension, dyslipidemia, PCOS– Maternal History of GDM (consider LGA)

Page 28: Childhood Overweight Childhood Overweight and Type 2 Diabetes

* Diabetes Care, volume 31, Supplement 1; January 2008: S14

TestingTesting

for Diabetes in Kids*for Diabetes in Kids*• Preferred test is a Fasting Plasma

Glucose• Diagnostic Criteria: plasma glucose

–Fasting (8+ hour) > 126 mg/dl–Oral glucose tolerance test: 2-hour

plasma glucose > 200 mg/dl–Casual (random) plasma glucose

> 200 mg/dl WITH symptoms• Confirm on subsequent day/test

Page 29: Childhood Overweight Childhood Overweight and Type 2 Diabetes

Laboratory evaluation• Other tests based on history and physical...• Family History, Symptoms or Signs of

Thyroid Disease• TSH

• Oligomenorrhea or Amenorrhea• Free Testosterone• LH• FSH• TSH• Prolactin

Page 30: Childhood Overweight Childhood Overweight and Type 2 Diabetes

Medical Complications of OverweightMedical Complications of Overweight

Phlebitis:venous stasis

Insipient CVD

Pulmonary disease:obstructive sleep apnea

Gall bladderdisease

Gynecologic:PCOS, Infertility

Diabetes

Joints: Arthritis, Slipped Capital Femoral Epiphysis

Cancer Risk Increase

Liver disease: steatosisSteatohepatitis, NAFLD Hypertension

Dyslipidemia

Skin

Idiopathic intracranial hypertension, pseudotumor c.

Pancreatitis

Page 31: Childhood Overweight Childhood Overweight and Type 2 Diabetes

Overweight Associated Overweight Associated Psychological ConditionsPsychological Conditions

• Depression• Anxiety• Low self esteem• Teasing/Bullying• Adverse socioeconomic outcome• Other social prejudices

Page 32: Childhood Overweight Childhood Overweight and Type 2 Diabetes

““The Metabolic SyndromeThe Metabolic Syndrome””

Adiposity, visceral

Type 2 diabetesHypertension

Dyslipidemia Impaired glucose tolerance

Acanthosis nigricans

Polycystic ovary disease

InsulinResistance

Adapted from Consensus Development Conference of the American Diabetes Association, Diabetes Care, 1997

Page 33: Childhood Overweight Childhood Overweight and Type 2 Diabetes

Childhood Hypertension Predicts Childhood Hypertension Predicts Adult HypertensionAdult Hypertension

• 20%-30% of overweight children have high blood pressure

• Overweight adolescents have 8.5 fold risk of hypertension as adults.**– Cardiac hypertrophy/LVH on ultrasound. – Long term risk of CVD and stroke.

• Treatment– Weight loss, low salt diet, pharmacotherapy

**Srinivasan Metab 1996;45:235-240.

Page 34: Childhood Overweight Childhood Overweight and Type 2 Diabetes

Adolescent Overweight Predicts Adolescent Overweight Predicts Adult Adult HyperlipidemiaHyperlipidemia

Overweight during adolescence associated with:• 2.4 X increase in prevalence of

cholesterol > 240mg/dl, • 3 X increase in LDL-C values >160mg/dl• 8 X increase in HDL-C values < 35 mg/dl

in adults 27-31 yo.

Srinivasan Metab 1996;45:235-240.

Page 35: Childhood Overweight Childhood Overweight and Type 2 Diabetes

Atherosclerosis begins in Childhood:Atherosclerosis begins in Childhood: Autopsy StudiesAutopsy Studies

• Bogalusa Heart Study: 2-15 yo• Pathological Determinants of Atherosclerosis in

Youth (PADY): 15-30• Raised coronary lesions in

– 7% Bogalusa– 24% PADY

• Correlates of coronary atherosclerosis– Body mass index – VLDL, LDL-C, HDL-C, triglycerides– Blood pressure

Berenson GS, et.al. N Engl J Med Jun 4; 338(23):1650-1656. Malcolm GT, Oalmann MC,. Annals New York Academy of Sciences pp 179-188

Page 36: Childhood Overweight Childhood Overweight and Type 2 Diabetes

Treatment and PreventionTreatment and Prevention

““ItIt’’s hard to know if yous hard to know if you’’re re failing unless you set yourself failing unless you set yourself

some goalssome goals…”…”Yogi Berra

Page 37: Childhood Overweight Childhood Overweight and Type 2 Diabetes

Recommended Weight GoalsRecommended Weight Goals

Weight loss approx. 1 pound/monthWeight goal: BMI< 85%

Sarah E. Barlow and William H. Dietz, Obesity Evaluation and Treatment: Expert Committee Recommendations, Pediatrics 1998 102: e29 http://www.pediatrics.org/cgi/content/full/102/3/e29

Page 38: Childhood Overweight Childhood Overweight and Type 2 Diabetes

AMA Prevention StrategiesAMA Prevention Strategies• Annually, measure height, weight, and calculate

BMI plus BMI percentile (level of evidence, C). • Encourage all children to participate in at least 60

minutes of moderate to vigorous physical activity on most, and preferably all, days of the week (level of evidence, A).

• Advise no more than 1 serving per day of sweetened beverages, such as fruit juice, fruit drinks, regular-calorie soft drinks, sports drinks, energy drinks, sweetened or flavored milk, or sweetened iced tea (level of evidence, B).

Page 39: Childhood Overweight Childhood Overweight and Type 2 Diabetes

AMA Prevention StrategiesAMA Prevention Strategies• Advise families to limit children's television

viewing and other screen time to 2 hours per day or less (level of evidence, B).

• Recommend that children's fast-food consumption be limited to no more than once per week (level of evidence, C).

• Advise families to eat meals together as often as possible, on most, and preferably all, days of the week (level of evidence, C).

Page 40: Childhood Overweight Childhood Overweight and Type 2 Diabetes
Page 41: Childhood Overweight Childhood Overweight and Type 2 Diabetes

Prevention of Pediatric Overweight and Prevention of Pediatric Overweight and Obesity: American Academy of Obesity: American Academy of

Pediatrics Policy StatementPediatrics Policy Statement• Prevention Summary:

http://www.pediatrics.org/cgi/content/full /120/Supplement_4/S229

• Very similar Strategies to AMA recommendations

• Treating GDM may reduce risk as well*

*Diabetes Care. 2007;30:2287-2292.

Page 42: Childhood Overweight Childhood Overweight and Type 2 Diabetes

And now for something And now for something completely differentcompletely different……

Page 43: Childhood Overweight Childhood Overweight and Type 2 Diabetes

““7521075210””

• Eat Breakfast 7 days a week–Could add eat together 7 days a week

• Eat 5 servings of Fruits and Veggies• Limit screen time to 2 hours or less daily• Participate in 1 hour of Physical Activity

daily• Drink 0 sodas or sweetened beverages on

a typical day*

*Yes, you can exclude the Chuck E Cheese birthday parties…

Page 44: Childhood Overweight Childhood Overweight and Type 2 Diabetes

AMA: Treatment StagesAMA: Treatment Stages• Stage I (Prevention-Plus Protocol): Make specific

dietary and physical activity recommendations, with monthly follow-up. If BMI does not improve in 3 to 6 months, consider stage II.

• Stage II (Structured Weight Management Protocol). Low–energy-dense, balanced diet; structured meals; supervised physical activity of at least 60 minutes daily; limiting television-watching and other screen time to 1 hour per day or less; and use of logs to self- monitor these behaviors. Family clinicians may require assistance from allied care professionals to implement this step, and children should be followed up as often as needed. If BMI does not improve in 3 to 6 months, stage III is appropriate.

Page 45: Childhood Overweight Childhood Overweight and Type 2 Diabetes

AMA: Treatment StagesAMA: Treatment Stages• Stage III (Comprehensive, Multidisciplinary

Intervention) and Stage IV (Tertiary-Care Intervention) More intensive interventions administered by highly trained teams expert in overweight management. Specialized centers can provide effective, intensive counseling programs that promote behavior modification for overweight children. Especially indicated for severely overweight children and for those with co-morbidities.

• Stage IV: tertiary care referral. • Many recommendations can be carried out by family

physicians for treatment and prevention. These include advice to limit consumption of sweetened beverages and fast food, limit screen time, engage in physical activity for at least 60 minutes per day, and encourage family meals on most (if not all) days of the week.

Page 46: Childhood Overweight Childhood Overweight and Type 2 Diabetes

Expert Committee Recommendations Expert Committee Recommendations Regarding the Prevention, Assessment, and Regarding the Prevention, Assessment, and

Treatment of Child and Adolescent Treatment of Child and Adolescent Overweight and Obesity:Overweight and Obesity:

• Summary:http://www.pediatrics.org/cgi/content/full/120/Supplement _4/S164

• Assessment: http://www.pediatrics.org/cgi/content/full/120/Supplement _4/S193

• Treatment:http://www.pediatrics.org/cgi/content/full/120/Supplement _4/S254

Page 47: Childhood Overweight Childhood Overweight and Type 2 Diabetes

Medications and SurgeryMedications and Surgery????• None Approved for Children Under 16, experimental only • Orlistat (Xenical®)

• Lipase inhibitor: decreased fat absorption• Adverse reactions: flatus, diarrhea

• Sibutramine (Meridia®)• Serotonin and norepinephrine reuptake inhibitor• Promotes feeling of fullness, increase calorie

expenditure• Adverse reactions: increases heart rate, increases BP• Adolescents 13-17 years: sibutramine + behavior

therapy lost 7.8 kg at 6 months compared to 3.2 kg for placebo and behavior therapy .

• Bariatric Surgery for Severely OverweightJAMA. 2003;289:1805-1812

Page 48: Childhood Overweight Childhood Overweight and Type 2 Diabetes

Overweight Children and Your Overweight Children and Your PracticePractice

• How will you improve the care of overweight children in your practice?

• What tools will you need?• What training will be needed?• How will measure the success of your

efforts?

Page 49: Childhood Overweight Childhood Overweight and Type 2 Diabetes

• Child Rearing

– Anglo-American: parent-focused responsibility

– Native American: community-focused child rearing - children are to be shared; discipline and nurturing responsibility of all

• Education

– Anglo-American: formal education stressed, individual achievement is stressed

– Native American: education occurs in all facets of life, individuals should learn from one another

• Implications for Intervention: Community based, Health Aides

Pediatrics Vol. 91 (5) Supp, May 1993 pp. 1063-1070

Cultural ConsiderationsCultural ConsiderationsNative Americans/Alaska NativesNative Americans/Alaska Natives

No cultural advice applies to everyone in a particular culture

Page 50: Childhood Overweight Childhood Overweight and Type 2 Diabetes

Cultural/Group SupportCultural/Group Support• Pima Pride/Action

-DPP pilot studyPeople randomized to “Action” group:

-Structured diet/exercise meetingsPeople randomized to “Pride” control group:

-Unstructured activities emphasizingPima culture and history

- “Pima Pride” group showed more positive outcomes on every biological parameter measured

Ann Bullock MDNarayan et al, Diabet Med 1998;15:66-72

Page 51: Childhood Overweight Childhood Overweight and Type 2 Diabetes

• Overweight adolescents have been shown to be more likely to skip breakfast and consume a few large meals per day than their leaner counterparts. (1)

• Although medically supervised weight control may be beneficial for overweight youths, some research suggests that for many adolescents, dieting to control weight is not only ineffective, it may actually promote weight gain. (2)

Adolescents and DietingAdolescents and Dieting

(1) J Am Diet Assoc. Vol. 101, 2001, pp. 798-802(2) Pediatrics Vol. 112 (4) 2003, pp. 900-906

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Page 53: Childhood Overweight Childhood Overweight and Type 2 Diabetes

Overweight Children and Your Overweight Children and Your PracticePractice

• Do you routinely provide advice or counseling for overweight children and their parents?

• What communication techniques do you use?

• How effective is your counseling?

Page 54: Childhood Overweight Childhood Overweight and Type 2 Diabetes

Overweight SensitivityOverweight Sensitivity“First Do no harm”

“Obesity”•

Ideal Weight

Personal Improvement

Focus on Weight•

Diets or “Bad Foods”

Exercise

Overweight•

Healthier Weight

Family Improvement•

Focus on Lifestyle

Healthier Food Choices

Play or Activity

Page 55: Childhood Overweight Childhood Overweight and Type 2 Diabetes

Prochaska & Di Clemente: Transtheoretical Model of Behavior Change

Action

Preparation

Contemplation

Relapse &Recycle

Maintenance

Pre-contemplation

Integrated Behavior

Stages of Behavior ChangeStages of Behavior Change

Page 56: Childhood Overweight Childhood Overweight and Type 2 Diabetes

Positive Family AttitudesPositive Family Attitudes

• Over a healthy weight is not a fault.• Avoid classifying “good” food or

“bad” food.• Emphasize staying physically active

rather than “exercising”• There is no ideal weight or body

shape.

Page 57: Childhood Overweight Childhood Overweight and Type 2 Diabetes

ParentsParents’’

ResponsibilitiesResponsibilities

• Have [pleasant?!] family meals.• Purchase and offer healthy foods and portion

sizes.• Role model good eating and activity behaviors.• Avoid using food as a reward.• Set limits on TV and video games.• Be flexible and understanding.• Encourage and show affection.

Page 58: Childhood Overweight Childhood Overweight and Type 2 Diabetes

ChildsChilds’’

ResponsibilitiesResponsibilities• To eat as much or as little as they need of the

foods available• To eat 3 meals a day with healthy snacks• To make activity fun• To try to be active every day• To be responsible for TV and video game

limits• To do things that they enjoy, give joy• To choose goals and areas to improve on

Page 59: Childhood Overweight Childhood Overweight and Type 2 Diabetes

How do you talk with parents who do not How do you talk with parents who do not consider their child overweightconsider their child overweight??

• “National experts have recommended using BMI to identify children who are overweight.”

• Show child’s BMI on BMI-for-age growth curve. “This means your child is at increased risk of becoming overweight as an adult and developing diabetes.”

• Ask them: “What do you think?”• “The good news is that making simple

changes in eating and physical activity can really reduce this risk. Are you interested in talking more about making family changes?”

Page 60: Childhood Overweight Childhood Overweight and Type 2 Diabetes

Additional Key Messages for Additional Key Messages for Parents of Overweight ToddlersParents of Overweight Toddlers• Change to low-fat or non-fat milk at 2 years

old.• Avoid telling your child to “clean the plate”.• Do not use food as a reward.• Keep offering foods that your child refuses

to eat. Praise your child for trying new foods.

• Wean from the bottle at 12-18 months. No bottle in bed.

Page 61: Childhood Overweight Childhood Overweight and Type 2 Diabetes

Case Study: Where from success??Case Study: Where from success??• 14 y/o BMI 40.3 (Ht = 5’ 1”, Wt = 213 lb)• 40.3 = BMI >>> 95%-ile• Acanthosis Nigricans• Both parents with type 2 diabetes• Seen in March of 2004, discussed healthy

eating habits, physical activity• Very soft sell, scheduled f/u 3 months• “Lost to follow up”

Page 62: Childhood Overweight Childhood Overweight and Type 2 Diabetes

Case Study: Where from success??Case Study: Where from success??

• Presented with mother following Spring• Lost 80 pounds, Acanthosis – gone!• BMI now 22.9 or 85%-ile• Stopped drinking sodas• Made modest changes in his own eating

habits• Voluntarily increased his physical activity

–Activities he enjoyed, martial arts• Engaged family in his changes

Page 63: Childhood Overweight Childhood Overweight and Type 2 Diabetes

Treatment of Type 2 in children?Treatment of Type 2 in children?

• MNT and Lifestyle changes• Insulin: always the safe first alternative• Metformin: approved, use enough• Other oral agents?? Byetta?• Beware the Type 1/Type 2 conundrum

–Check antibodies and C-peptide (later)

Page 64: Childhood Overweight Childhood Overweight and Type 2 Diabetes
Page 65: Childhood Overweight Childhood Overweight and Type 2 Diabetes

Case Study: Type 1 Case Study: Type 1 vsvs

Type 2?Type 2?

• 16 year old presents in DKA• Treated with i.v. insulin, responds well• BMI 39.1, >> 95%-ile• Acanthosis Nigricans• Grandfather, type 2 diabetes, mom s/p

gastric bypass, BMI > 40.

Page 66: Childhood Overweight Childhood Overweight and Type 2 Diabetes

Case Study: Type 1 Case Study: Type 1 vsvs

Type 2?Type 2?

• Further work-up: + Islet Cell antibodies• Marginal BG’s on insulin, but

markedly improved metabolic balance• Addition of Metformin (titrated)

resulted in further BG improvement, decrease in basal insulin requirements

• What kind of diabetes does he have?

Page 67: Childhood Overweight Childhood Overweight and Type 2 Diabetes

What about Lipids? AAP says:What about Lipids? AAP says:• “For patients 8 years and older with an LDL

concentration of 190 mg/dL (or 160 mg/dL with a family history of early heart disease or 2 additional risk factors present or 130 mg/dL if diabetes mellitus is present), pharmacologic intervention should be considered.”

• Goal = 160 mg/dl, 110-130 mg/dl if FHx CVD• Treatment options: Fibrates, Niacin, Statins• http://www.pediatrics.org/cgi/content/full/122/

1/198

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Childhood OverweightChildhood Overweight

The Role of Schools The Role of Schools and Communitiesand Communities

Page 69: Childhood Overweight Childhood Overweight and Type 2 Diabetes

Overweight Prevention in SchoolsOverweight Prevention in SchoolsAn Opportunity for Parent AdvocacyAn Opportunity for Parent Advocacy

• Salad bars and other low cost healthy meal options.

• Bans on soda contracts.

• More PE (200 minutes every 10 school days).

• More fun PE, non-competitive activities.

• Walk to school events (www.cawalktoschool.com)

• Integrate health promotion into curriculum.

• Link activities – school and home.

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Preventing childhood obesity by reducing Preventing childhood obesity by reducing consumption of carbonated drinks: consumption of carbonated drinks:

Cluster Randomized Controlled TrialCluster Randomized Controlled Trial• Setting: Six primary schools in southwest England. • Participants: 644 children aged 7-11 years• Intervention: Focused educational program on nutrition

over one school year.• Results: Consumption of carbonated drinks over three

days decreased by 0.6 glasses in the intervention group but increased by 0.2 glasses in the control group. At 12 months the percentage of overweight children increased in the control group by 7.5%, compared with a decrease in the intervention group of 0.2%.

BMJ 2004;328:1237 (22 May)

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Prevention of Overweight and Type 2 DiabetesPrevention of Overweight and Type 2 Diabetes• Multifaceted, multi-sector interventions may be more effective

(schools, communities, health care, work-site).• Evidence based strategies with local adaptation may be an

effective approach.• Sustained interventions (over 5 years) may be needed.• Key intervention strategies include:

• Increasing physical activity and breastfeeding.• Decreasing sedentary behavior and sweetened beverage

consumption.• Evaluation, sustainability and dissemination need to be

considered.• Behavior change strategies can be augmented with policy and

built environment changes.Pediatrics Vol. 112 No. 4 October 2003, pp. e328-346

Pediatrics Vol. 115 No. 4 April 2005, pp. 1142-1147

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Questions? Questions? Final thoughtsFinal thoughts……

““You've got to be careful if you don't You've got to be careful if you don't know where you're going, because know where you're going, because

you might not get there.you might not get there.”” SoSo……“…“…if you get to a fork in the road,if you get to a fork in the road,

take it.take it.””Yogi Berra