chromosome geography lecture. the chromosome as a polymer blob b=2p
Post on 21-Dec-2015
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![Page 1: Chromosome Geography Lecture. The Chromosome as a Polymer Blob b=2P](https://reader030.vdocuments.net/reader030/viewer/2022032522/56649d6b5503460f94a4ae85/html5/thumbnails/1.jpg)
Chromosome Geography LectureChromosome Geography Lecture
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The Chromosome as a Polymer BlobThe Chromosome as a Polymer Blob
b=2P
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Chromosome Geography @ CaltechChromosome Geography @ Caltech
Sturtevant and Morgan Benzer
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Chromosome Geography: Genomic vs. Chromosome Geography: Genomic vs.
physical positionphysical position
Cremer and CremerLucy Shapiro
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Fluorescence In-Situ Hybridization Fluorescence In-Situ Hybridization
(FISH)(FISH)
http://www.microscopyu.com/articles/fluorescence/insitu/brennerinsitu.html
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Schemes for Mapping Chromosome Schemes for Mapping Chromosome
GeographyGeography
Gitai et al, 2005
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Yokota et al, 1995
Quantifying the GeographyQuantifying the Geography
Gasser, Science 2002
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Quantifying the GeographyQuantifying the Geography
Heun, Gasser, Science 2001 Bystricky, Gasser, PNAS 2004
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Quantifying the GeographyQuantifying the Geography
Sachs et al.
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The Immune SystemThe Immune System
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The Immune SystemThe Immune System
Kees Murre, UCSD
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oriCI
oriCII
xy
Pro
babili
ty
Pro
babili
ty
x
y
Replication origins are confined!(Theriot et al.)
Chromosome Geography in VibrioChromosome Geography in Vibrio
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Models for Chromosome SegregationModels for Chromosome Segregation
Gitai et al, 2005