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CINF E-News Volume 1, No. 1 Fall 1999 Edited by Bruce Slutsky CINF members have communicated with each other through: CINF Website CHMINF-L Chemcial Information Bulletin (printed CIB) The aim of this new electronic newsletter is to expedite the flow of information among CINF members. Those unable to attend recent national meetings will learn of many of the technical programs before the publication of the next CIB. This first issue will include: MESSAGE FROM THE CHAIR WELCOME NEW MEMBERS Committee Reports Program Education Awards American Chemical Society Joint Board-Council Committee on Patents and Related Matters (CP & RM) Reports from the New Orleans Meeting Combinatorial Chemical Information Alternative Careers in Chemistry CINF Historical Column by Val Metanomski Announcements from STN International

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Page 1: CINF E-News · Web viewCombinatorial Chemical Information Alternative Careers in Chemistry CINF Historical Column by Val Metanomski Announcements from STN International STN Newsline-September

CINF E-NewsVolume 1, No. 1

Fall 1999

Edited by Bruce Slutsky

CINF members have communicated with each other through:

CINF WebsiteCHMINF-LChemcial Information Bulletin (printed CIB)

The aim of this new electronic newsletter is to expedite the flow of information among CINF members. Those unable to attend recent national meetings will learn of many of the technical programs before the publication of the next CIB. This first issue will include: MESSAGE FROM THE CHAIR

WELCOME NEW MEMBERS

Committee Reports

ProgramEducationAwardsAmerican Chemical Society Joint Board-Council Committee on Patents and Related Matters (CP & RM)

Reports from the New Orleans Meeting

Combinatorial Chemical InformationAlternative Careers in Chemistry

CINF Historical Column by Val Metanomski

Announcements from STN International

STN Newsline-September 3, 1999STN Newsline-October 1, 1999Ebsco CAS Press Release-October 1, 1999

Techniques for Markush SearchingPoetry Corner by Bartow CulpChemistry Site Seeing by Steve Rosenthal

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CINF People in the News

Andy BerksBob BuntrockPatricia O'NeillEdlyn Simmons

CINF Meritorious Service AwardChemistry and the Internet Symposium 99

Message from the ChairDear Colleagues,

Welcome to the first issue of CINF's electronic newsletter, the CINF E-News! I'm really excited that we are going to take advantage of the benefits electronic publishing offers. Many thanks to everyone who contributed articles. A special note of thanks to Bruce Slutsky, Editor of CINF E-News, for all of his efforts in launching this inaugural issue. For everyone reading this letter, I would like to encourage you to contribute items to future issues.

There are several items of CINF business that I'd like to communicate in this letter. CINF Meritorious Service Award: The CINF has a Meritorious Service Award has been forgotten the past several years. In recognition of all the talented and hard-working members in the Division, please consider nominating a colleague for this Award. Please see CINF Meritorious Award information in this issue of E-News for more details.

Election Results-New officers elected in CINF for 2000 are:Chair Elect: Andrea Twiss-BrooksSecretary: Maggie JohnsonCouncilor: Gary WigginsAlternate Councilor: Joanne Witiak

Many thanks to everyone who ran for office and congratulations to the winners! Remember that there are many roles and opportunities to become active within the Division.

Wondering what getting more active in the Division might mean? Check out the CINF Procedures Manual (http://www-sul.stanford.edu/depts/swain/edcinf/manual.html) which is now available on the CINF Web site. While being involved does mean commiting some time and effort, it is very rewarding. So please, join in the

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fun and help set future priorities and directions for the Division by joining a committee or running for office.

Strategic Plan: If you haven't had a chance already, please check out the draft of CINF's Strategic Mission: http://www.lib.uchicago.edu/~atbrooks/CINF/strategic_plan.html. Feedback and suggestions are most welcome. The CINF Executive Board plans to finalize this document at the Spring 2000 ACS National Meeting so please send us your thoughts before then. We want to make sure that the course we set and the priorities we choose meet your professional needs.

By-Laws: The CINF ByLaws are in the process of being revised. In the coming months Robert Stoubough will be working with the ACS Committee on Constitution and Bylaws to review proposed changes for the CINF Divisions ByLaws. Upon completion of this review process, CINF members will be asked to vote to amend the ByLaws. Stay tuned...

Do you have a Change of Address? If yes, it is now possible to update your address online at this URL: http://center.acs.org/applications/addrupdate/addrchange.cfm

Well, let me stop before this letter gets too long. Many thanks for all your support and contributions to CINF activities! I look forward to seeing you at the next ACS National Meeting where we will ring in the new millenium, learn cool things at symposia, network at Division events, and help catalyze and shape future directions in chemical information. Cheers!

Grace BaysingerCINF Chair

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New CINF MembersWe would like to welcome the following new members to CINF:

Jon Chistan BaberPaul N.W. BaxterLawrence W. BledsoeDouglas Allen CasadeYili ChenLarry ChenLinda L. Clement

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Timothy P. CutlerGanesh S. EthirajLee W. HermanJunping JingCindy Mesaros-ButchkoAlfian NoorUjung PandangKashima IbargiDeana ParksLoren PenneyBrenda RamosIvelisse RiveraArlene RolandCarolyn RootErin A. SmithLeah SollaRuben D. Sorto AlvaradoRobert B StorchHengxu WeiYaron Yapaport

Thanks to Mike O'Hara with providing the list.

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Program Committee ReportThe program committee has arranged six symposia for the upcoming San Francisco ACS meeting, which will be held on March 26-31, 2000:

Modelling and Informatics for Non-ExpertsOrganizer: Osman Guner, Molecular Simulations Inc.tel: (858)799-5341, fax: 858-458-0136, email: [email protected]

Experimental, Computational, and Informatics Challenges of ADME/Tox in early stage drug discoveryOrganizer: Osman Guner and Kenneth Merz, Molecular Simulations Inc.tel: (858)799-5341, fax: 858-458-0136, email: [email protected]

Chemical Information Needs at the Graduate LevelOrganizer: Grace Baysinger, Stanford University, Swain Librarytel: (650)725-1039, fax: 650-725-2274, email: [email protected]

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Joint CSA/CINF Symposium: Chemical Information and E-CommerceOrgnanizer: Bryan Vickery, ChemWeb, Inc.tel: + 44-171-499-4748, fax: +44-171-499-4102, email: [email protected]

Chemical Information in the 21st CenturyOrganizer: Bob Snyder, MDL Information Systemstel: 510-895-1313, fax: 510-614-3652, email: [email protected]

Electronic Notebooks: Technology and User InterfaceOrganizer: Rich Lysakowski, The Collaborative Electronic Notebook Systems Associationtel: 781-935-9600, fax: 781-935-3113, email: [email protected]

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ACS Division of Chemical Information Education Committee

Report of Activities, September 1998-August 1999

The division paid $500 to Indiana University in support of graduate students who worked on various projects for the CINF Education Committee (EdCom). Students were primarily employed in updating the Clearinghouse for Chemical Information Instructional Materials and assisting with other projects undertaken or under consideration by EdCom. For example, they did an extensive mailing to solicit new material to include in the CCIIM, working with Silvia Lee to identify approximately 60 potential contributors. The following CCIIM pages have been updated with their assistance in the last 12 months (See at: http://www.indiana.edu/~cheminfo/cciimtoc.html):

Works Devoted to Major Tools or Databases:31 Chemical Abstracts: Printed and Database32 Science Citation Index: Printed and Database33 Beilstein Handbook of Organic Chemistry: Printed and Database

Other:03 Computer Searching Aids: General06 Chemical Patent Searching10 Physical Property Searching11 Chemical Synthesis or Reactions

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40 How to Teach Chemical Information50 Chemical Information Course Syllabi

EdCom presented the Teaching Chemical Information workshops at the Boston (August 1998) and Anaheim (March 1999) ACS National Meetings, with 9 and 8 attendees respectively. Due to communication and other problems, the full workshop was not presented at the SLA Conference in June 1999. However, Bartow Culp and Dana Roth presented a standing room-only session there on "Chemistry and Chemistry Librarianship for the Nonchemists" that had in excess of 120 people in attendance. The supply of handouts was quickly exhausted, and still 80 attendees requested to receive the handout. After the meeting they were either sent information by the IU SLIS graduate student about the location on the Web of the PDF file (http://www.indiana.edu/~cheminfo/slachem.pdf ) or were sent paper copies of the 30-page handout. Furthermore, two people who planned to attend the aborted Teaching Chemical Information workshop in Minneapolis held an informal 1 1/2-hour discussion with Chuck Huber and Gary Wiggins.

In recent months, the committee has begun to investigate the desirability of developing materials for high school as well as to assess the gaps in instructional materials for teaching the use of the CrossFire system for searching Beilstein and Gmelin. The SLIS students at Indiana University have evaluated and categorized a large number of Beilstein Web sites and compiled an Excel spreadsheet with their results, available at: http://www.indiana.edu/~cheminfo/beilstein_training.xls

Arleen Somerville has had extensive discussions with the ACS Committee on Professional Training about ways in which EdCom could have more input into CPT Guidelines. Arleen also gave a presentation in August 1998 to the Society Committee on Chemical Abstracts about the need to provide low-cost access to the Chemical Abstracts database for educational purposes, especially in smaller schools.

Respectfully submitted,Gary Wiggins, Chair, EdCom, 1998-2000

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AwardsThe 1999 winner of the Herman Skolnik Award for outstanding achievement in chemical information is Stuart M. Kaback in recognition of his leadership and contributions to patent information searching and chemical information

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searching in general. Stu's biography may be found on page 10 of the Fall 1999 Chemical Information Bulletin. At the recent New Orleans National Meeting Stu organized and presided over a symposium titled "The Changing Chemical Information Scene: Keeping and Nuturing the Baby as the Bathwater Rushes By.

At the New Orleans meeting, it was announced that G.W.A. (Bill) Milne, and Stephen Heller will be the co-recipients of the 2000 Skolnik Award to be presented at the Fall Meeting in Washington, D.C. Among many other accomplishments Bill Milne has been Editor of the Journal of Chemical Information and Computer Sciences for a number of years. Stephen Heller's biography may be found at http://www.hellers.com/~steve.

The Chemical and Engineering News of October 4, 1999 (page 44) reports that the American Chemical Society Columbus and Dayton Sections have selected Stephen E. Stein as the recipient of the 1999 Austin M. Paterson-E.J. Crane award for outstanding achievements in chemical information theory and practice. Stein, a National Institute of Standards and Technology fellow and head of NIST's Mass Spectrometry Data Center, was selected for contributions he made as leader of the institute's program on mass spectral data.

Ellen Mimnaugh received the Special Libraries Association (SLA) 1999 Hall of Fame Award. This honor is given to a member of SLA at or near the end of a professional career in recognition of an extended and sustained period of distinguished service to that association. Ellen recently retired as product manager for online services at Chemical Abstracts Service. She was also an active contributor to CINF.

Hearty congratulations to all award winners.

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American Chemical Society Joint Board-Council Committee on Patents and Related

MatterReported by David Saari

Recent developments in legislation and regulations, education and outreach projects, and nominations for national awards were discussed. A summary of important legislation and proposed regulations follows.

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H.R. 1907 (Passed by the House Aug. 4, 1999)

Covers invention promotion services, first inventor defense (previously called prior user rights), patent term guarantees, publication of U.S. patent applications, inter partes reexamination, a reorganization of the USPTO (the bill does not establish the USPTO as a government corporation), and miscellaneous provisions, including electronic filing and publication and exclusion of certain commonly assigned patents as prior art.

The first inventor defense section has been worded to apply only to methods of doing business. The current language of the bill is vague, but the intent (according to House committee staff) is to protect Internet commerce from patents on methods of doing business (which are not supposed to be granted in the first place). The committee recommended that the ACS ask the Senate to clarify the language when they consider the bill.

U.S. patent applications would be printed 18 months after the first filing date. Applicants can request that an application not be published if the application has not been the subject of an application filed in another country. The legislation does not specify how applications are to be published except to say, "in accordance with procedures determined by the Director."

Further, Title VII, Sec. 704, allows for electronic filing and electronic publication of patents.

Sec. 707 adds Sec. 102(e) ("the invention was described in a patent granted on an application for patent by another filed in the United States before the invention thereof by the applicant for patent. . .") to the list of subsections (previously just (f) and (g) ) that are excluded as prior art if the invention is owned by the same person. This change may impact what can be considered as prior art in patent searches.

The full text of H.R. 1907 is available on the Library of Congress THOMAS web site.

H.R. 1714

Makes electronic signatures as legally binding as written signatures. Nothing in the bill specifically mentions electronic record keeping for patent purposes or regulatory documents and submissions. The bill seems to be limited to "any contract or agreement entered into or affecting interstate or foreign commerce."

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OMB Circular A-110

Applies the principles of Freedom of Information to data created by grant recipients when used in rulemaking.

E-biomed

The proposal by NIH Director Harold Varmus to create a government-operated electronic repository for biomedical publications is opposed by ACS and many other scientific societies.

H.R. 354

The Collections of Information Antipiracy Act again attempts to protect databases using principles of unfair competition. A similar bill H.R. 1858 offers similar protection but without criminal penalties. Three proposals have been introduced in the Senate.

H.R. 1598/S. 1172

Provides patent term extensions to drugs under review by the FDA in 1984 (prior to the enactment of the Hatch-Waxman Act).

Awards

CP&RM is looking for suggestions for nominations for certain national awards, specifically the National Inventors Hall of Fame and the National Medal of Technology. The National Medal of Technology is awarded by thePresident for achievement in applied science.

CINF ACTION ITEM: Previous recipients of the Skolnik Award who have madesignificant contributions to the technologies used in our industry shouldbe considered for nomination by the ACS for a National Medal of Technology. Please send me your recommendations.

Please contact me if you have questions or comments about any of the items mentioned in this report.

David [email protected]

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Combinatorial Chemical InformationSubmitted by Robert Snyder

The take-home message from the Combinatorial Chemistry Informatics sessions is that chemical informatics is playing an even more important role in the planning, building, and analysis of combinatorial libraries. Smaller, more "intelligent" libraries are being planned to a greater extent than a few years ago using information on physical-chemical properties. Information from the planning stage is used to drive automated synthesizer. And results from HTS are electronically collected and stored in relational databases, where they can be correlated with chemical structures.

There were a total of twenty (20) talks divided into four sessions. The first session focused on library design. Library design can be the most critical aspect in determining the success or failure of the resulting combinatorial library. Selection of the scaffold and R-groups (reagents) can have a profound effect on how well the library members bind to the desired target receptor. Julian Hayward (Synopsys) spoke on some of the advantages of designing combinatorial libraries using a generic reaction representation. Andrew Leach (Glaxo Wellcome) outlined a computational method for the classification and selection of monomers for combinatorial libraries. Douglas Henry (MDL Information Systems) described a unique decision support approach to designing reagent libraries. Alfonso Pozzan (Glaxo Wellcome) developed an in-house program called VOLGA (Virtual Optimization of chemical Libraries using Genetic Algorithm) which has allowed them to optimize the design of a wide class of chemical libraries by choosing among different fitness functions. John Barnard (Barnard Chemical Information Ltd.) described software to generate structural fingerprints for molecules in a library by direct analysis of a Markush representation.

The second session focused in virtual library analysis/diversity assessment. This session provided insight on the creation and analysis of virtual combinatorial libraries as a means for pre-screening libraries prior to their synthesis. Moises Hassan (MSI) showed how a diverse, drug-like library can be designed by optimizing R-group fragments to simultaneously maximize the molecular diversity and minimize a penalty function based on the specified properties of the products. Katherine Andrews-Cramer (Tripos) showed how lead-hopping and library-hopping by topomer shape similarity searching of very large virtual libraries can be used to analyze library components. Jan Pedersen (Acadia Pharmaceuticals) used statistical approaches for creating maximal diversity in a HTS screening library. Ryan Koehler (Telik) described a new algorithm for simultaneously addressing the need for both diverse and enriched compounds with "drug-

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like" properties in a library. Tim Mitchell (Cambridge Combinatorial) described the Atlas Informatics system.

The third session focused on automated synthesis and validation. This session covered information management and tracking methods for all steps of medium or high throughput synthesis. This includes experimental set-up, synthesis techniques, purification methods for synthesized compounds, analytical methods for compound verification, and registration of validated compounds. Robert Pearlman (University of Texas) discussed methods for assessing and comparing the diversities of chemical libraries. Xiao Chuan Wang (Trega Biosciences) extended Robert Pearlman's presentation by applying a new measure, percentage of overlapped cells (POC), within all drug space in their inter-library diversity analysis to compare how different one library is from others and to design a new library. David Chapman (Afferent Systems) presented an integrated structural, synthetic, and analytical system for combinatorial chemistry informatics. Antony Williams (Advanced Chemistry Development) talked about SLIMS - a web-based system for sample, structure and spectral management. Maurizio Bronzetti (MDL Information Systems) discussed the importance of integration with the research environment and tools for accomplishing this.

The fourth session tied everything together with high-throughput screening. Combinatorial libraries pose unique challenges to software programmers and developers who provide informatics programs for the drug discovery industry. These challenges include controlling robotic workstations used to create the libraries as well are register and validate the libraries before they are run in high-throughput screening (HTS) programs. Robert Trinka (Robocon GmbH) described new technology building blocks and how they can be fitted into automated laboratories reaching data outputs of a quarter million data points per 24 hours and beyond. George Cowan (Parke-Davis Pharmaceutical Research) analyzed the use of version spaces to the analysis of high-volume structure-activity relationships. Antony Williams (Advanced Chemistry Development) demonstrated software to allow the databasing of MS and NMR spectral curves associated with molecular structures and the application of NMR prediction algorithms. Harold Helson (CambridgeSoft Corp.) demonstrated software to manage combinatorial data in Excel. Glenn Myatt (Columbus Molecular Software) introduced and demonstrated visualization software for chemical and biological screening data.

Submitted by Robert Snyder

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Alternative Careers in Chemistry Symposium

held at the 218th American Chemical Society National Meeting

August 23, 1999Submitted by Andrea Twiss-Brooks

The "Alternative Careers in Chemistry" symposium was designed to present a look at a variety of careers dealing in chemical information and to provide guidance to new chemistry graduates and to chemists looking for alternatives to laboratory research. Opportunities for alternative careers described by the participants were described as exciting options for chemists, being integrally involved in the research and teaching processes, offering significant opportunities for personal and professional development, and providing a variety of possible career paths. Highlights of each presentation are given below:

Employment and marketability: ACS Career Services and you.

Jean Parr from ACS Career Services Division presented an overview of the membership of the ACS. Fifty-five percent of ACS 160,000 members are listed as "chemists"; the remaining 45% list management, teaching, science writing, and other jobs. According to ACS studies, members will make 7-10 job changes with 3 different employers during the course of their careers. ACS offers a variety of products and services to help with these career changes. A recent publication, "Careers for Chemists: A World Outside the Lab", which featured information from more than 70 interviews with professionals in conservation, law, regulatory management, science writing, finance, medicine, among others. ACS Career services offers over 100 titles in print, video, and web format. Also highlighted was the Online PDB (Professional Data Bank) which offers ACS members a service to match jobs to chemists. More information is available from their web site at: http://www.acs.org/careers/.

Strategic partnering for knowledge management.

Suzanne Cristina form UTC Information Network provided a fascinating profile of a chemical information specialist working in a dynamic environment . As a proactive information specialist, her goal is to "make chemists and engineers aware of ways to partner with information professionals to save time and money and to promote knowledge flows in

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their organizations". Suzanne described several projects and services in which the information services staff were real partners in the research and development process. One example was the inclusion of an information professional as part of a design team for a new helicopter part. By attending group meetings, Suzanne was able to integrate the information component into the research and design process.

The study of applied organic chemistry in graduate school and at a remote university.

Forrest Schultz, a professor of chemistry at the University of Wisconsin-Stout described a career of teaching and research at a non-Ph.D. granting institution in a remote rural area. Success in maintaining a research program in an undergraduate institution relies on an approach of "inquiry based learning", a willingness of faculty to use undergraduate students in "real" research, and increasing availability and accessibility of remote chemical information resources via the WWW. Schultz emphasized working during graduate studies to take charge of the process and develop contacts between departments and disciplines of study.

Managing dynamic chemical information environments in industry.

Keith Schreiber of Procter & Gamble described aspects of his career in an industrial environment. Participation in multiple, varied projects, opportunity to use both scientific and information knowledge, ability to solve challenging problems, facilitate other's use of information, think dynamically, and communicate effectively are the hallmarks of an information career in an industrial setting. Effective chemical information specialists may be involved at many levels of company operations, have opportunities for career advancement, and can indulge a keen curiosity.

Look! Up in the sky! It's a chemist! It's a librarian! It's both!

Bartow Culp treated us to a lively and thoughtful presentation. Some of the rewards of a career as an academic chemistry librarian highlighted included contact with people, involvement in the research and education process, as well as with colleagues, even at an international level, a degree of autonomy, and variety afforded by the fast changing field of librarianship. Enhancing the presentation were a number of quotes from practicing academic chemistry librarians.

From laboratory to law office: a career as a patent attorney.

Anita Varma from Foley, Hoag & Elliot LLP described her career path from laboratory to patent examiner to patent lawyer in a law office. An overview

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of the patent process and the place of the patent attorney and patent examiner were described. Jobs in patent law that do not require a law degree were mentioned. Skills required in patent work include organization, analytical reasoning, problem-solving, communication, as well a sound technical background in the area of practice. Patent specialists can work writing patents, litigating, examining and searching.

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CINF History Cornercompiled by W. Val Metanomski

Topics of CINF papers presented at the ACS National Meetings were selected against the international and national background, with emphasis on chemistry and chemical documentation.

50 YEARS AGO (1949)

Cornerstone is laid for the United Nations building in New York with President Truman in attendance.Berlin airlift, which delivered 2.3 millions tons of food and coal to West Berlin, ends when the Soviet Union lifted its 321-day-long blockade.BINAC computer is demonstrated to compute 12,000 times the speed of the human brain.William J. Wiswesser introduces Wiswesser Line Notation (WLN).William F. Giauque receives Nobel Prize in Chemistry for studies on chemical thermodynamics at very low temperatures.Austin M. Patterson becomes the first recipient of the Award for Documentation in Chemistry, named after him and established by the ACS Dayton Local Section.CINF papers:

1. "Microcards - The New Method of Publication". F. Rider (Wesleyan University).

2. "A Use for Punched Cards in an Industrial Research Laboratory". R. Nicholsen et al.(Archer Daniels Midland).

3. "An Efficient Method of Duplicating Chemical Information on Cross-Reference and Punched Cards". W. Longenecker (U.S. Public Health Service).

4. "Some Mathematical Possibilities in Mechanical Indexing and Sorting Systems". C. S. Wise (Northern Regional Research Laboratory).

25 YEARS AGO (1974)

U.S. Congress enacts the Freedom of Information Act and overrides President Ford's veto.

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Dr. Henry Heimlich announces a new technique for saving life of a person chocking on food.A new particle, psi, is discovered.Willard F. Libby reports on the use of carbon-14 to determine the age of objects.Paul J. Flory receives Nobel Prize in Chemistry for theoretical and experimental studies on physical chemistry of polymers.CINF papers:

1. "The Crossbow Search System - Capabilities and User Requirements". P. A. Baker (Imperial Chemical Industries).

2. "Planning for Effective Use of Online Systems". J. S. Buckley, Jr. (Pfizer).3. "Structure-Reactivity Correlations for Organic Molecules by Pattern

Recognition". J. R. Koskinen and B. R. Kowalski (University of Washington).

4. "Toxline Chemical Dictionary File". B. M. Vasta et al. (National Library of Medicine).

10 YEARS AGO (1989)

The Berlin Wall, a 28-mile long concrete and barbed-wire barrier that divided Berlin since August 1961, is dismantled.Exxon Valdez spills 11 million gallons of crude oil in Prince William Sound in Alaska.AZT is shown to delay the onset of AIDS, indicating the value of treating HIV-positive individuals.Tetrahydron Computer Methodology, (W. Todd Wipke, editor) becomes the first journal published in electronic form (on floppy discs).Thomas R. Cech and Sidney Altman receive Nobel Prize in Chemistry for the discovery of catalytic activity of RNA.George E. Vladutz receives the Austin M. Patterson-E. J. Crane Award for pioneering contributions to the theory and practice of the computerized indexing and retrieval of chemical reactions.CINF papers:

1. "European Patent Office Automation Plan". M. Bare and J. Michel (European Patent Office).

2. "Entrepreneurship in Chemical Information - The MDL Experience". S. Marson (Maxwell Communication Corp.).

3. "Consumer-Driven Access to Scientific and Technical Information, 1990's and Beyond". D. H. Smith (Molecular Design Ltd.).

4. "The Future of Chemical Database Searching:Online/Mainframe or CD ROM/PC?". C. Jochum (Beilstein).

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Announcements from STN InternationalSTN Newsline-September 3, 1999

This information was adapted from STN Newsline dated September 3, 1999

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Enhanced Patent Information: 1. IMPROVED PATENT CURRENCY IN CAPLUS2. HYPERLINKS TO PATENTS FROM U.S./EUROPEAN PATENT OFFICES3. PATENT FILE ON STN--(PATIPC)4. FILE DATA IN PATOSWO (correction)

File Enhancements:5. LINK--ACS JOURNAL REFERENCES TO CAS FILES6. WAYS TO TRUNCATE TERMS7. NAME CHANGE8. FILE-IMSPROFILES9. MECUM--NEW ADDRESS10. FILE-ESBIOBASE

New Capabilities of STN on the Web:11. SEARCH PREVIEW/NEW TRANSCRIPT FORMAT/UPLOAD COMMAND FILE

Special Offer:12. CONNECT HOUR IN IMSPROFILES

_________________________________ENHANCED PATENT INFORMATION

1. IMPROVED PATENT CURRENCY IN CAPLUSCAS is now providing information within days that often takes months to appear in other databases. Patent records are available in the CAplus database within two days after the patents are issued by the U.S., Japanese, and WIPO patent offices. Fully indexed patent records for these key patent offices are also appearing in the CAplus database within record-breaking time from publication - typically just 30 days, and in many cases fewer, from date of issue.

2. HYPERLINKS TO PATENTS FROM U.S./EUROPEAN PATENT OFFICESCAS has also enriched its database records with hypertext links that take researchers from CAS services such as STN directly to full-text patent documents at the U.S. and European Patent offices. This feature was announced earlier in 1999 and is accomplished through the ChemPort Connection included in all CAS electronic search services. Users of these services can link to full-text patent documents almost as fast as they can identify them in the CAS databases, allowing them to complete the research cycle online in the same session. These patent documents are available immediately and at no charge to users.

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For additional information about these 2 enhancements, see the Press Release at: http://www.cas.org/New1/currency.html

3. NEW PATENT FILE ON STN-(PATIPC)PATIPC was released on August 29, 1999. The file contains the text and graphics of the International Patent Classification (IPC) as published by the World Intellectual Property Organization (WIPO) and the German Patent and Trademark Office (DPMA). The English text is available for IPC edition 1-6. The German text is available for edition 4-6.

In addition to the IPC text, the database contains the Catchword Index of edition 6 as provided by the DPMA. The Catchword Index is available in English and German.

Please note that this file is targeted at users familiar with the IPC structure.

The PATIPC file is updated with every new IPC edition. Edition 7 is expected in 2000.

For pricing, see HELP COST in the file.

4. BACKFILE DATA IN PATOSWO (CORRECTION)The years for the backfile were stated incorrectly in the previous issue. The correct years for the backfile in PASTOSWO are 1978-1982.

____________________FILE ENHANCEMENTS

5. INSTANT LINK-ACS JOURNAL REFERENCES TO CAS FILESNow, users of ACS electronic journals will be able to link immediately from references to the relevant CAS record, gaining instant access to the abstract and bibliographic information.

Through an innovative new program developed through the ChemPort Connection, readers of such prestigious publications as The Journal of the American Chemical Society, The Journal of Organic Chemistry and Organic Letters are now able to click on the "CAS" tag following references at the end of 1999 articles and retrieve (if available) the corresponding bibliographic information and abstract in the CAplus database.

The ChemPort Connection is built into each of CAS' electronic services, including STN Express with Discover!, STN Easy, and STN on the Web.

For more details, see the Press Release at: http://www.cas.org/New1/reflinking.html

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6. MORE WAYS TO TRUNCATE TERMSSimultaneous right and left truncation is now available in the Basic Index of these files: AIDSLINE, CANCERLIT, EMBASE, TOXLINE, TOXLIT, USPATFULL

You can now retrieve a more comprehensive set of answers with a single search term.

7. FILE NAME CHANGEThe name of IFIRXA is now IFI Current Patent Legal Status (IFICLS). IFIRXA will be retained as an alias-the file content remains the same.

8. NEW FILE-IMSPROFILESIMSworld Phamaceutical Company Profiles from IMS HEALTH

This file is a significant addition to the group of files on STN that are particularly relevant to the pharmaceutical business market. The internal make-up of more than 100 key pharmaceutical companies worldwide are collected and analyzed in the IMSworld Pharmaceutical Company Profiles (IMSPROFILES) file from IMS HEALTH. Users can access status information concerning chemical trials, drug approvals, and drug phases.

IMSPROFILES contains more than 23,850 records and is updated monthly (SDIs run monthly and quarterly.) SDIs provide a convenient method of staying current concerning management changes, strategic statements, major company events, and product updates.

See SPECIAL OFFER below.

For more information, visit the July/August issue of STNews at: http://www.cas.org/STNEWS/JULYAUGUST99/imsprofiles.html

9. VADEMECUM-NEW ADDRESSThe producer address information is:RAABE Fachverlag fuer WissenschaftsinformationKaiser-Friedrich-Strasse 9010585 BerlinGERMANY

10. NEWFILE-ESBIOBASEESBIOBASE is a comprehensive bibliographic database of worldwide biological research that covers the entire spectrum of biological information. Sources are more than 1,700 international research journals from 1994 to the present. The database presently contains more than 1.2 million records and grows by about 250,000 records each year. ESBIOBASE is very

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current with many records available online within two to three weeks after receipt of the original journal. Updates and SDIs are weekly.

The database contains bibliographic data, author's keywords, and author's abstracts in approximately 70% of the records. Additionally, each document is indexed using a unique and versatile classification scheme that is updated annually to adapt to changing research trends.

The indexing fields classification code (CC), author's keywords (ST), and organism name (ORGN) feature simultaneous left and right truncation, which is especially beneficial when searching the terminology used in the life sciences.

See HELP COST in the file for pricing information.

______________________________________NEW CAPABILITIES OF STN ON THE WEB

11. FREE SEARCH PREVIEW/NEW TRANSCRIPT FORMAT/UPLOAD COMMAND FILE (available September 12, 1999)Free Search Preview: This feature will allow you to try your search query in STN on the Web before logging in. Search Preview allows a limited use of STNindex to visually demonstrate the wealth of information that is available on STN. Click on the "Free Search Preview" button from the Login Screen to try it out.

New Transcript Format: The versatile Rich Text Format (RTF) is available for downloading session transcripts and exporting them into a wide variety of popular word processing packages. The zipped RTF/GIF format includes all images displayed during the session. The direct RTF format does not include images, is a larger file taking longer to download, and does not require use of a ZIP program.

Upload Command File: Professional searchers can create complex search strategies offline, and then upload these command (script) files to an STN on the Web session for efficient execution, thereby minimizing connect time charges for typing and correcting commands. Command scripts can be submitted one line at a time or all at once. A script command line may be edited before it is submitted.

______________SPECIAL OFFER

12. One FREE connect hour in IMSPROFILES each month in September and October 1999.

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____HELP

As always, additional information or search assistance is just a click away: http://www.cas.org/faq.html#call

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Announcements from STN InternationalSTN Newsline-October 1, 1999

New Files:1. ALUMINIUM2. IMSDRUGCONF3. WTEXTILES

Enhanced Patent Information:4. PROVISIONAL APPLICATIONS IDENTIFIED5. CURRENCY IMPROVED FOR EPO PATENTS IN CAPLUS

File Enhancements:6. CEABA-RELOADED AND ENHANCED7. CHEMLIST-TSCA INFORMATION UPDATED8. ESBIOBASE-ADDED TO CLUSTERS9. INPADOC/INPAMONITOR-COMBINED10. METADEX-ADDED TO CLUSTER11. TOXLIT-SDI FREQUENCY CHANGE

STN EASY Enhancements:12. ELIMINATE NEED FOR MULTIPLE LOGINIDS/PASSWORDS

SPANISH VERSION AVAILABLESIGN-UP SCREENS IN JAPANESEQUICK TIPS IN FRAMES VERSION

FYI:13. NEW-STN INFORMATION KEEP & SHARE PROGRAM14. SEVERAL DOCUMENT SUPPLIERS NO LONGER AVAILABLE15. PHARMA WEB PAGES UPDATED

__________NEW FILES

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1. ALUMINIUMAluminium Industry Abstracts Produced by Cambridge Scientific Abstracts, ALUMINIUM provides international coverage from 1968 to present. Coverage includes the world's technical literature on aluminum, ranging from ore processing through business developments and applications from scientific and technical journals, government reports, conference proceedings, dissertations, books, and patents (until 1996). ALUMINIUM corresponds to the printed Aluminium Industry Abstracts. The file contains more than 207,000 records and is updated monthly with about 750 records. This database has been included in the ALLBIB, AUTHORS, COMPANIES, CORPSOURCE, CHEMISTRY, ENGINEERING, MATERIALS, and METALS clusters. The Database Summary Sheet is available in STNGUIDE and on the Web and will be included with the Sep/Oct issue of STNews. For pricing, see HELP COST in the file. For more information, visit: http://www.cas.org/ONLINE/DBSS/aluminiumss.html

2. IMSDRUGCONFIMSworld Medical and Pharmaceutical Meetings Diary IMSDRUGCONF from IMS HEALTH is a directory of worldwide medical and pharmaceutical meetings and conferences. The meetings are classified by therapy areas. Records contain meeting titles, locations, organizers, dates, E-mail and URL addresses, and the therapy area. Hot links giving you point-and-click access from IMSDRUGCONF to cited URLs, are available while using STN Express with DISCOVER! The file contains more than 4,300 records and is updated monthly. SDIs may be run monthly or quarterly, with monthly as the default. The Database Summary Sheet is available in STNGUIDE and on the Web and will be included with the Sep/Oct issue of STNews. For pricing information, see HELP COST. For more information, visit: http://www.cas.org/ONLINE/DBSS/imsdrugconfss.html

3. WTEXTILESWorld Textiles Produced by Elsevier Science, this file provides comprehensive coverage from 1970 to the present of the current international textiles literature, i.e., digests of scientific, technical and techno-economic literature relevant to fiber-forming polymers, textile and related industries and the applications of fibrous and textile materials in conventional textile products. Covered are 500 scientific, technical and trade journals, books, reports, conference reports, and statistical publications, as well as UK, US, and European (EP) patents and standards. WTEXTILES contains more than 210,000 records and grows by about 7,200 records per year. It is updated monthly. The Database Summary Sheet is available in STNGUIDE and on the Web and will be included with the Sep/Oct issue of STNews. This file has been added to the ALLBIB, AUTHORS, CORPSOURCE, MATERIALS, and POLYMERS clusters. See

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HELP COST in the file for pricing information For additional information, visit: http://www.cas.org/ONLINE/DBSS/wtextilesss.html

_________________________________ENHANCED PATENT INFORMATION

4. PROVISIONAL APPLICATIONS IDENTIFIED Provisional applications are now identified in IFICDB, IFIPAT, IFIUDB, and USPATFULL and are displayed on the Priority Application Information (PRAI) line. IFICDB, IFIPAT, and IFIUDB have also had their annual reload.

5. CURRENCY IMPROVED FOR EPO PATENTS IN CAPLUSStarting October 6, 1999, Caplus will have 2-day currency for EPO patents.

____________________FILE ENHANCEMENTS

6. CEABA-RELOADED AND ENHANCEDThe leading language of this database has been changed from German to English. Text is now in English for the complete file in the Controlled Term (CT) , Classification (CC), Document Type (DT), and Language (LA) fields. German controlled terms and classification text are searchable in fields /CTDE and /CCDE. Review your SDI queries to be sure your terms are being searched in the correct field. CEABA has also been enhanced with highlighting of hit terms, the new search field Controlled Word (/CW), and the new display formats DALL, IBIB, and IALL. For more information, visit: http://www.cas.org/ONLINE/DBSS/ceabass.html

7. CHEMLIST/HCHEMLIST-TSCA INFORMATION UPDATEDTSCA Inventory Tape information is current through July 9, 1999 as provided by the July 1999 version from NTIS.

8. ESBIOBASE-ADDED TO CLUSTERSESBIOBASE has been added to the AGRICULTURE, ALLBIB, AUTHORS, BIOSCIENCE, CORPSOURCE, ENVIRONMENT, HEALTH, MEDICINE, PHARMACOLOGY, and TOXICOLOGY clusters.

9. INPADOC and INPAMONITOR-COMBINEDINPADOC and INPAMONITOR have been combined into a new INPADOC file on STN. The INPAMONITOR and INPADOCOLD file have been removed.

10. METADEX-ADDED TO CLUSTERThis file has been added to the ENGINEERING cluster.

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11. TOXLIT-SDI FREQUENCY CHANGETOXLIT is updated weekly. SDIs may be run weekly or monthly-weekly is the default.

__________________________STN EASY ENHANCEMENTS

12. ELIMINATE NEED FOR MULTIPLE LOGINDS/PASSWORDSQualifying customers can now have selected STN accounts set up to access STN Easy via IP address authorization. To learn more, visit:http://stneasy.cas.org/html/english/ipaainfo/ipaamain.html

SPANISH VERSION AVAILABLEIn addition to English, French, German, and Japanese, the information in the use of STN Easy is now translated into Spanish.SIGN-UP SCREENS IN JAPANESEIf you access STN Easy through the Japanese node, you can now sign up for STN Easy in Japanese. All of the Account Sign-Up screens, including the Terms and Conditions, are now available in Japanese.QUICK TIPS IN FRAMES VERSIONEarlier this year a link to Quick Tips was added on the navigation bars that run along the top and bottom of STN Easy. Now this link also appears in the frames version.

___FYI

13. NEW-STN INFORMATION KEEP & SHARE PROGRAMThe STN Information Keep & Share Program is an optional program that makes it easy for you to purchase the right to archive and/or redistribute STN search results in a way that is compliant with database producers' usage terms and policies. You can use this program with STN and STN on the Web search results. The cost to purchase the archival or redistribution rights for STN search results is a flat surcharge per record. For more information, visit: http://www.cas.org/copyright/index.html STNote No. 22-STN Information will be distributed with the Sep/Oct STNews and is available on the WWW at: http://www.cas.org/ONLINE/STNOTES/stnoe22.html. A Quick Reference Card will also be distributed with STNews and is available on the WWW at: http://info.cas.org/ONLINE/QR/keepshare.pdf NOTE, the STNote and QRC in PDF require the Adobe Acrobat Reader.

14. SEVERAL DOCUMENT SUPPLIERS NO LONGER AVAILABLEThe following document suppliers are no longer available on STN: EMD, GEO, INI, IPS, IRB, ISI, MIS, NIW, NTB, NTI, PIR, and WPS. For a list of document suppliers, see HELP ORDER SUPPLIER.

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15. PHARMA WEB PAGES UPDATEDIf it has been awhile since you took a look at what STN has to offer to the pharma searcher-you'll want to visit: http://www.cas.org/PHARM/pharm.html

____HELP

As always, additional information or search assistance is just a click away: http://www.cas.org/faq.html#call

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Announcements from STN InternationalEbsco CAS Press Release-October 1, 1999

Following is the content of a press release issued by EBSCO in cooperation with CAS.

CAS and EBSCO Subscription Services to Link Databases and Full Text Electronic Journals

BIRMINGHAM, Ala., U.S.A. - In a move to further provide researchers with access to information, EBSCO Subscription Services and Chemical Abstracts Service (CAS) have announced a linking partnership. Once these links are completed in the first quarter of 2000, researchers will be able to link from CAS database resources via the ChemPort (SM) Connection to the full text of journal articles contained on EBSCO Online (R).

"We see the linking agreement with CAS as a significant step toward our goal of providing our customers all of the information choices that they expect," said Mark Williams, manager of Electronic Content Development for EBSCO Online. "EBSCO Online's strategic aim is to provide every logical partnership possible so users can search and seamlessly link to full text."

"CAS is delighted to join with EBSCO Online in making a wealth of science-related literature more readily available to our customers," said CAS marketing director Suzan A. Brown. "The CAS/EBSCO linking partnership puts users in touch with a prestigious group of publishers collaborating to build a unique digital research environment for scientists." STN users searching with STN Express with Discover, STN Easy or STN on the Web; SciFinder or SciFinder Scholar users; and CA on CD customers will be able

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to link from search results directly to full text articles available on EBSCO Online.

EBSCO Online is a World Wide Web-based service that provides a single source for all aspects of a comprehensive electronic journal collection. Users can go to one URL and use one search engine to search across journal content from a variety of publishers and access the full text. Administrators can choose from a variety of authentication methods to make access easy for users depending on their needs.

"Linking has become synonymous to total customer satisfaction in electronic information delivery," Williams said. "This is what the ChemPort Connection/EBSCO Online linking agreement is intended to deliver."

EBSCO customers have access to more than 3,600 electronic journals through EBSCO ONLINE, and content is available from a number of publishers, including more than 350,000 articles from more than 30,000 individual issues. "Our content is among the richest in the industry," Williams added. "STM publishers from around the world and in leading disciplines are included in this service. We aggregate much of the content and provide links to those publishers that wish to aggregate content themselves."

CAS, a division of the American Chemical Society, produces the world's largest and most comprehensive databases of chemical information, including more than 18 million abstracts of chemistry-related literature and patents and more than 20 million substance records. CAS publishes Chemical Abstracts (CA), related publications and CD-ROM services; operates the CAS Chemical Registry; produces a family of online databases; and offers the SciFinder desktop research tool. CAS operates STN International, a network of scientific and technical databases, in association with FIZ Karlsruhe in Germany and Japan Science and Technology Corporation. The CAS Web site is at http://www.cas.org/

EBSCO Subscription Services is part of the EBSCO Information Services Group, which provides fully integrated serials access and delivery solutions worldwide through print and electronic subscription services, reference database development and production and online multi-database access. The EBSCO Information Services group also includes EBSCO Publishing. For more information, please visit the EBSCO World Wide Web site at http://www.ebsco.com/.

Reported by Eric ShivelyEric Shively

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[email protected]

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Techniques for Markush Searchingfrom Edlyn Simmons

There are quite a few articles about techniques for searching Markush structures, many of which begin with a summary of what a Markush structure is. Here's a brief excerpt from a presentation I gave last month at the ACS National Meeting. (Editors note--this was also posted to CHMINF-L)

"A Markush structure has grown to designate any chemical structure that contains a required substructure and one or more variable or optional chemical groups. Patent attorneys usually denote Markush groups by the letter R, but other notations are also common. One feature is essential ? groups that are not stated to be either required or optional are forbidden ? positions in organic molecules shown without substitutents have all empty valences satisfied by hydrogen atoms unless the patent says something about optional substitution. The structure can include variable positions of substitution, variable numbers of substituents, variable bonding, optional substituents, variable chain lengths, and provisos defining combinations of substituents that are forbidden in the claimed genus. A Markush structure represents each of the compounds you can construct by combining the variables, the the notation used to describe the structure as a whole has no special meaning."

These are some publications on Markush structures:

Markush or Generic Structures. J. Chem. Inf. Comp. Sci. 1991, 31 (1), 1. Simmons, Edlyn S. The grammar of Markush structure searching: vocabulary vs syntax. J. Chem. Inf. Comp. Sci. 1991, 31(1), 45-53.Barnard, John M. Online graphical searching of Markush structures in patents. Database, 10(3) 27-34 (1987).Barnard, John M. A comparison of different approaches to Markush structure handling. J. Chem. Inf. Comp. Sci. 31(1), 1991, 64-68.4.Schoch-Grübler, Ursula. (Sub)Structure Searches in Databases containing Generic Chemical Structure Representations. Online Review 14 (2), April 1990, pp. 95-108.

Additional articles are listed on the Patent Information Users Group website, under Patent Information Knowledge Base.

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Edlyn Simmons: Section Head Business Information ServicesThe Procter & Gamble Company5299 Spring Grove Ave.Cincinnati, Ohio 45217Phone: (513) 627-5664, Fax: (513) 627-6854Email: [email protected]

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Poetry Cornerby Bartow Culp

Here are some poems for the CINF Electronic Bulletin. They are known as "Clerihews", after Edmund Clerihew Bentley (1875-1950), who invented the form.

Said Berthelot to Berthollet"Have you seen Lavoisier?""I saw his head not long ago."Said Berthollet to Berthelot.

Sir Humphrey DaveyComplained of the gravy:"It needs some more salt on."Said he to John Dalton.

Said van der Waals to van't Hoff"I think you are a pompous oaf.""Your attitude simply appalls."Said van't Hoff to van der Waals

Leopold GmelinThought his eyesight was failin'."To cover the world of GeneralchemieIs simply too much work for me."So, rather than go into a panicHe restricted his handbook to Inorganic.

Gordon & BreachSat on the beach

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Wondering, with many lamentationswhy no one subscribed to their publications.

Herbert C. BrownTurned upside downThe notion that the chemistry of organoboronswas a subject fit only for the rankest of morons.

Watson and CrickAccomplished the trickof helically spiraling nucleotides,and thereby won the Nobel Prize.This was especially gallingTo Pauling.

Reed ElsevierSold their journals so dearThat only the most well-heeled of scholarsCould come up with sufficient dollars.

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Chemistry Site Seeingby Steven Rosenthal

(Editors note--I found many of these sites useful. Please check them out)

I would like to present some chemistry related sites that contain useful or interesting information. But before I start I would like to recommend a very useful general site for information searchers. Ever get the question where do I start? Well here is the answer. The site is called the Cyber Times Navigator. The url is:http://www.nytimes.com/library/tech/reference/cynavi.html

The Cyber Times Navigator is a great place to start searching and is the place where the New York Times reporters begin their forays into the net. The author of the Navigator is Rich Meislin. The links are organized into 11 parts as follows: Net search, Journalism, Reference, Directories, Politics, New York Region, Commerce, Entertainment, Sports, and Miscellany. Net search lists over 25 different search engines. The Reference Desk includes links to Carl Uncover, National Library of Medicine, Medline, The Merck Manual, US Patents provided by IBM and many other sources. The site is

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free however, you must register with the New York Times to use the Navigator and New York Times on the Web.

Below is a partially annotated list of sites containing chemically relevant material:

International Union of Pure and Applied Chemistry (IUPAC) sitehttp://www.iupac.org/Martindale's Reference DeskScience called this a gold mine of science resourceshttp://www-sci.lib.uci.edu/HSG/Ref.htmlGlossary of oceanography and related termshttp://www-ocean.tamu.edu/~baum/paleo/paleogloss/paleogloss.htmlPatentshttp://www-sul.stanford.edu/depts/swain/patent/pattop.htmlA list of patent related web-sites is maintained by the European Patent Office as a service to usershttp://www.epo.co.at/online/index.htm#databasesPedro's BioMolecular Research Toolshttp://www.public.iastate.edu/~pedro/research_tools.htmlThe Analytical Chemistry Springboardhttp://www.anachem.umu.se/jumpstation.htmCHEMINFO Chemical Information sourcesCHEMINFO will help you find and learn how to use chemistry information resources on the Internet and elsewhere. CHEMINFO is compiled and maintained by Gary Wiggins.http://www.indiana.edu/~cheminfo/CORDIS, The Community R&D Information Servicehttp://www.cordis.lu/Surfactants Virtual Library (Surfactant Science Web Sites)This site contains links to surfactant and detergent related web sites. The referenced sites contain information on companies, research centers, researchers, phenomena such as foaming, detergency, micelles, surface tension, emulsions, microemulsions, and applications such as cleaning, cosmetics, environmental remediation, etc. Links to over 800 sites are compiled in this virtual library. The site is maintained by Dr. Paul Huibers at the Massachusetts Institute of Technology, Department of Chemical Engineering.http://web.mit.edu/huibers/www/surfsite.htmPolyContent Web SitePolyContent compliments PolyLinks as the index to technical and business content worldwide regarding the plastics industry. Content is broken down into logical groups and also by technical level. This allows PolyContent to serve both the industry novice and the Phd level.http://www.polymers.com/dotcom/polycon/BioTech's Life Science DictionaryThis free resource was developed by the staff members and contributors and is still very much under construction. Currently, most of the 8300+ terms deal with biochemistry, biotechnology, botany, cell biology and genetics. There are also some terms relating to ecology, limnology, pharmacology, toxicology and medicine. Don't expect to find common or exotic animals here; there are far too many species

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to cover even a fraction in a resource like this. Some medically- and biotechnologically-relevant organisms such as bacteria, worms, fungi, and some plants are included.http://biotech.icmb.utexas.edu/Glossary of Biochemistry and Molecular Biology onlineby David Glick of he Hebrew University of Jerusalem, IsraelThis book compiles nearly 3000 terms - some appear only in earlier literature, some very current, some are common terms invested with new meanings, some are lab jargon - and gives succinct definitions to them. The explanations assume a basic familiarity with the biosciences, and should therefore be useful to advanced students and to workers in related fields who wish to converse with other biochemists or molecular biologists in their native tongue. References are included with many of the entries, in order to assist the reader in searching for additional information. These citations, frequently review articles, are offered as a convenient introduction to the literature on the subject. Also included is a bibliography of additional references.http://db.portlandpress.co.uk/glick/search.htmGlossary of Soil Science TermsThe February 1997 revision replaces the July 1987 edition and includes major revisions and additions. Soil Science Society of Americahttp://www.agronomy.org/sssagloss/

Another soil glossary. This one is compiled by Robert B. Harrison. http://weber.u.washington.edu/~robh/S-7/soilglossary.htmlUSGS groundwater glossaryThe definitions found in this glossary are from, "The federal glossary of selected terms: Subsurface-water flow and solute transport": Department of Interior, U.S. Geological Survey, Office of Water Data Coordination, August 1989. References for the definitions are included at the end of the document.http://wwworegon.wr.usgs.gov/projs_dir/willgw/glossary.htmlDictionary of Cell BiologyOn-line searchable feature is available at the site.The Dictionary of Cell Biology was first published in 1989, and has since been translated into several languages. It is intended to provide quick access to easily-understood and cross-referenced definitions of terms frequently encountered in reading the modern biology literature. This server contains the text of the Second edition, published in April 1995, together with enhancements, hypertext links and new entries which are destined for the third edition. There are 5450 entries and 5772 cross-references in the second edition.http://www.mblab.gla.ac.uk/~julian/Dict.htmlGenetics glossaryhttp://helios.bto.ed.ac.uk/bto/glossaryScience Hypermedia siteScience Hypermedia, Inc. is developing educational course ware for general chemistry, analytical chemistry, instrumental analysis, optics, and electronics. Click on the Index of Educational documents on this server for a list of topics covered or select a tutorial on Analytical Chemistry basics, Solving Equilibrium problems (under construction), or Analytical Spectroscopy (under construction).http://www.scimedia.com/index.htmlMineralogy Database

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http://web.wt.net/~daba/Mineral/index.htm by David Barthelmy Mineralogy Database in HTML Format. Last update 7/29/98. This mineral database contains more than 5,000 pages of mineral data. There are 3,968 individual mineral species descriptions with links. Visit the "What's New" section for details. Mineral data on individual species are closely HTML-linked to the following mineral table by crystallography, chemical composition, physical and optical properties, Dana's New classification, Strunz classification, and alphabetical listings of mineral species. I have also included links to other sources of mineral data available on the WWW. Also includes mineral pictures. Links for Chemists http://www.liv.ac.uk/Chemistry/Links/links.html Links for Chemists lists over 5300 Chemistry sites on the WWW. Links are organized into a number of sections or related topics. The major sections are introduction, plug-ins, university departments, chemical companies, chemical information, chemical societies, funding bodies, topics, other link sites, and about this site.ChemWebhttp://chemweb.com/

The World Wide Club for the Chemical Community. A free site containing a large variety of chemical related materials.

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Andy BerksOn July 12, 1999, Andy started working at the Merck and Co. Rahway, New Jersey site, as a Senior Information Scientist in the Patent Dept., reporting to Bob Murawski. Bob's group provides information and searching support to the patent department, which handles work including patent prosecution, licensing, and other patent related legal matters for Merck.

Prior to this position, Andy was at Wyeth Ayerst in Pearl River, New York, for ten years. Andy has a Ph.D. in organic chemistry from the University of Colorado in Boulder.

Andy is licensed to practice before the U.S. Patent and Trademark Office, and has authored numerous publications, and regularly presents at American Chemical Society national meetings. He is currently the chair person of the Program Committee, for the the 1999-2000 term, and is a past chair person of the Patent Information Users Group.

Andrew H. Berks, Ph.D.Sr. Information ScientistMerck & Co.126 E. Lincoln Ave RY60-35Rahway, NJ 07065-0900

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732-594-1701 fax [email protected]

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Bob BuntrockAfter almost 30 years in Naperville, IL, Bob and Gloria Buntrock have moved to Minnesota. We found our dream retirement home near Princeton, about 50 miles from Minneapolis. We have an 11 year old house on 12 acres, overlooking a small, limited recreational lake (that means no motors). After dividing time between the two houses all summer, we moved complete in early September. Most of the boxes are unpacked and we're enjoying the beautiful fall season.

Buntrock Associates, Inc. will continue in business, but at a reduced level. We're planning on a fuller, but not complete retirement. If you're in the area and peace and quiet appeal to you, give us a call and pay us a visit -- directions upon request.

11335 300th Ave. NWPrinceton, MN 55371612-389-8370FAX 612 389-8371

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Patricia O'NeillIn August, Patricia E. O'Neill became the Assistant Professor -- Science Librarian, at Pacific Lutheran University (her alma mater) in Tacoma, Washington. "Moving to this position will give me a chance to work with the science faculty to develop a strong undergraduate information literacy program. Having served as Physical Science Librarian at Cornell and Chemistry Librarian at Emory University, I am aware of what undergraduate students need to know about science information to make their transition to graduate school easier. I'm am thoroughly enjoying coming home to PLU. I also look forward to the renewed opportunity to be active again in the Division of Chemical Information."

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Please feel free to contact her at:Mordvedt LibraryPacific Lutheran UniversityTacoma, WA [email protected]

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Edlyn SimmonsEdlyn Simmons retired from her position as manager of the Patent Information Group at Hoechst Marion Roussel on July 31, 1999, due to the closure of the HMR Patent Department's Cincinnati, OH, office. On August 2, Edlyn began a new position as Section Head in Procter & Gamble's Business Information Services department. In her new position, Edlyn is responsible for managment of BIS searching support for the Fabric and Home Care business unit at Ivorydale Technical Center and oversees patent searching activities at all of P&G's Cincinnati sites.

Edlyn S. SimmonsSection HeadBusiness Information ServicesThe Procter & Gamble Company5299 Spring Grove Ave.Cincinnati, Ohio 45217Phone: (513) 627-5664Fax: (513) 627-6854Email: [email protected]

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ACS Division of Chemical InformationMeritorious Service Award

Name of Award: ACS Division of Chemical Information Meritorious Service Award.

Purpose: To recognize outstanding contributions to the Division.

Page 34: CINF E-News · Web viewCombinatorial Chemical Information Alternative Careers in Chemistry CINF Historical Column by Val Metanomski Announcements from STN International STN Newsline-September

Candidates for Award: Members of the Division who have performed activities benefiting the Division and deserving of special recognition. The current Chair, Chair-Elect, Treasurer, and Secretary are ineligible to receive this award.

Frequency: The award may be given to more than one person a year.

Nature of the Award: An engraved plaque or a framed certificate.

Process for the Award: A call for nominations will be published in printed and electronic publications for the Division and on the CINF Web site. Nominations may be submitted to the Awards Committee by letter, fax, or email, with a deadline of two months before a given National Meeting. The Awards Committee will receive nominations and select award winner(s). The Chair of the Division will notify the winner(s). The award will be presented at the Division luncheon at the following National Meeting. A press release will be prepared by the Awards Committee and will be sent by the Awards Committee to the same printed and electronic venues as other Division award announcements.

Criteria for the Award: Membership in the Division and outstanding contributions to the Division. For example, continuing leadership of the Division in a particular area or sustained active contribution to major tasks over many years. Nominations should document these contributions and be supported by three seconding letters.

Previous Winners: 1992 W. Val Metanomski1994 Barbara G. Wood (Prewitt)

Chemistry and the Internet Symposium 99

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