ciprofloxacin 7
TRANSCRIPT
-
8/8/2019 Ciprofloxacin 7
1/3
Ciprofloxacin
7
mg IV q12h
Bactericidal;interfereswithDNAreplication insusceptiblebacteria
preventingcellreproduction
Indications:
For the treatment
of infections
caused by
susceptible gram-
negative bacteria
including E. coli,
P.
mirabilis, K.
pneumoniae,
Enterobacter
cloacae, P.
vulgaris, P.rettgeri, M.
morganii, P.
aeruginosa,
Citrobacter
freundii, S.
aureus, S.
epidermidis,group
D streptococc
Contraindications:
Allergy to
ciprofloxacin,
norfloxacin orother
fluoroquinolones,
pregnancy,
lactation
CNS:Headache,
dizziness, insomnia,
fatigue, somnolence,
depression, blurred
vision
CV:Arrhyt hmias
hypotension, angina
EENT: Dry eye, eye pain,
keratopathy
GI:Nausea, vomiting, dry
mouth,diarrhea,
abdominal pain
Hematologic:Elevated
BUN, AST, ALT, serumcreatinine and alkaline
phosphatase;
decreased WBC,
neutrophil count, Hct
Other: Fever, rash
Assess patient
for signs
andsymptoms
ofinfection
Obtain C/S
before
beginnin
drug therapy
Assess for
anaphylaxis
Identify urine
output
Monitor blood
studies
Monitor
electrolytes
Assess bowel
pattern daily
Monitor for
bleeding
Precautions:
Pregnancy,
lactation,
children, renal
disease,
epilepsy
Simvastatin40mg/tab 1
InhibitsHMG-CoA ications Contraindications CNS:Headache,asthenia, Assess
-
8/8/2019 Ciprofloxacin 7
2/3
tab OD at hs(p.o.
reductase,theenzyme thatcatalyzes thefirststep in thecholesterol
synthesispathway,resulting in adecrease inserumcholesterol,serumLDLs, andeitheran increaseor nochange inserumHDLs.
Adjunct to diet in
the treatment of
elevated total
cholestrol and
LDL
cholesterol with
primary
hypercholesterole
mia (types IIa and
IIb) in those
unresponsive to
dietary restriction
of saturated fat
and cholesterol
and othernonpharmacologic
measures
To reduce the risk
of coronary
disease, mortality,
and CV events,
including stroke,
TIA, MI and
reduction in needfor bypass
surgery
and angionplasty
in patients with
coronary heart
disease and
hypercholesterole
mia
Treatment ofpatients with
isolated
hypertriglyceridem
ia mia
Contraindicated
with allergy to
simvastatin,
fungal
byproducts,
pregnancy,
lactation
Treatment of type
III
hyperlipoproteine
sleep disturbances
GI: Flatulence, diarrhea,
abdominal pain,
cramps, constipation,
nausea, dyspepsia,
heartburn, liver failure
Respiratory:Sinusitis,
pharyngitis
Other:Rhabdomyolysis,
acute renal failure,
arthralgia, myalgi
nutrition:
fat, protein,
carbohydrates
Monitor bowel
pattern daily
Monitor
triglycerides,
cholesterol
baseline
throughout
treatment
Precautions:
Past liver
disease,
alcoholism,
severe acute
infections,
trauma,
severe
metabolic
disorders,
electrolyte
imbalances,
elderly, renal
disease
-
8/8/2019 Ciprofloxacin 7
3/3
Treatment of
adolescents 10-
17
yr with
heterozygous
familial
hypercholesterole
mia