cir expert panel meeting august 30-31, · pdf filecir expert panel meeting august 30-31, 2010...

GREEN BOOK 2

&

GREEN BOOK 3

Vegetable Oils

Nut Oils

CIR EXPERT PANEL MEETING

AUGUST 30-31, 2010

GREEN BOOK 2

Oils


AUGUST 30-31, 2010

CIR Panel Book Page 1

Memorandum

To: CIR Expert Panel Members and Liaisons

From: Christina L. Burnett, Scientific Writer/Analyst

Date: July 30, 2010

Subject: Draft Report of the Vegetable Oil Group

The Scientific Literature Review (SLR) for this group of edible vegetable (and fruit) oils was announced April 23, 2010. A related SLR on edible nut oils was announced in June of this year, and is to be reviewed by the Panel at this meeting as well. If the Panel does not see any major differences in the overall toxicity potential of these two oil groups, it may consider combining the reports into one major edible oil report.

Both reports are taking a slightly new approach to reviewing multiple related ingredients at one time and are including oil ingredients that have previously been reviewed by the CIR Expert Panel, which are designated in italic print.

At the time that the SLR was announced, CIR sought the following additional information:

1. Manufacturing information about oils used in cosmetic formulation, particularly on methods used to remove non-fatty acid components (e.g., glycidol fatty acid esters);

2. Cosmetic grade specifications, if such exist, for oils used in cosmetic formulations.

3. Fatty acid composition for those oils covered in this report (where such information has not been provided or differs from what is presented).

4. Irritation and sensitization testing on cosmetics (finished products) containing specified concentrations of oils covered in this report.

5. Irritation and sensitization testing on those fatty acids present in the oils covered in this report that have previously not been reviewed by CIR.

6. Any other information that pertains to the safety of the use in cosmetics of the oils covered in this report.

Data on fatty acid compositions and cosmetic grade specifications, as well as an HRIPT studies on numerous oils have been received from the Personal Care Products Council and are incorporated in this draft report in Tables 3, 4, and 7, respectively. Due to the voluminous amount of unpublished data (800+ pages), data will be accessible online. Paper copies will be mailed out only by request.

Please note that the new use table is being employed in this report. The raw data from which the table was created along with any available concentration of use information have been included in the book materials.

If the data provided are sufficient for the Panel to assess the safety of these ingredients, a tentative conclusion should be developed regarding their safety in cosmetics, along with a rationale for that conclusion. The report will then be issued as a Tentative Safety Assessment. If additional data are needed, these should be identified and an Insufficient Data Announcement should be issued.

For your convenience, the materials for this report can also be found at http://www.cir-safety.org/aug10.shtml.


CIR Expert Panel History with Vegetable Oils April 2010 - CIR issued a Scientific Literature Review.


Literature Search on Vegetable Oils

1

Ingredients Toxline PubMed

ChemIDplus HSDB CAplus NTIS HPV Merck USP

√ √ √ √ √ √ √ Ingredients were searched by Latin botanical (INCI) names, common names, and CAS numbers, when available. The list of ingredients searched is found in Table 1 of the vegetable oil report. Literature searches included chemical composition, fatty acid composition, dermal toxicity, irritation, and sensitization qualifiers.

Searches were performed between November 20, 2009 and March 30, 2010 and updated June 30 through July 8, 2010.


Report


Draft Report

Vegetable Oil, Related Plant-Derived Oils, and Other Derivatives

as Used in Cosmetics

August 30, 2010 The 2010 Cosmetic Ingredient Review Expert Panel members are: Chairman, Wilma F. Bergfeld, M.D., F.A.C.P.; Donald V. Belsito, M.D.; Curtis D. Klaassen, Ph.D.; Daniel C. Liebler, Ph.D.; Ronald A Hill, Ph.D. James G. Marks, Jr., M.D.; Ronald C. Shank, Ph.D.; Thomas J. Slaga, Ph.D.; and Paul W. Snyder, D.V.M., Ph.D. The CIR Director is F. Alan Andersen, Ph.D. This report was prepared by Christina L. Burnett and Monice Fiume, Scientific Analyst/Writers.

© Cosmetic Ingredient Review 1101 17th Street, NW, Suite 412 " Washington, DC 20036-4702 " ph 202.331.0651 " fax 202.331.0088 "

[email protected]


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TABLE OF CONTENTS

INTRODUCTION ................................................................................................................................................................. 1

Chemistry ............................................................................................................................................................................... 1

Processing ...................................................................................................................................................................... 2

Analytical Methods ............................................................................................................................................................ 2

Impurities ....................................................................................................................................................................... 2

Use ......................................................................................................................................................................................... 3

Cosmetic ............................................................................................................................................................................ 3

Non-Cosmetic .................................................................................................................................................................... 4

ANIMAL TOXICOLOGY .................................................................................................................................................... 4

OILS .............................................................................................................................................................................. 4

Dermal Irritation/Sensitization/Phototoxicity .................................................................................................................... 4

Adansonia Digitata Seed Oil [Baobab] .......................................................................................................................... 4

Carthamus Tinctorius (Safflower) Oil ........................................................................................................................... 4

Gossypium Herbaceum (Cotton) Seed Oil..................................................................................................................... 4

Elaeis Guineensis (Palm) Oil ......................................................................................................................................... 5

Olea Europea (Olive) Fruit Oil ...................................................................................................................................... 5

Oryza Sativa (Rice) Bran Oil and Germ Oil .................................................................................................................. 5

Sesamum Indicum (Sesame) Seed Oil ........................................................................................................................... 5

Triticum Vulgare (Wheat) Germ Oil ............................................................................................................................. 6

Zea Mays (Corn) Oil ...................................................................................................................................................... 6

Ocular Irritation ................................................................................................................................................................. 6

Adansonia Digitata Seed Oil [Baobab] .......................................................................................................................... 6



Linum Usitatissimum (Linseed) Seed Oil ...................................................................................................................... 6

Olea Europea (Olive) Fruit Oil ...................................................................................................................................... 7

Oryza Sativa (Rice) Bran and Rice Germ Oil ................................................................................................................ 7

Ribes Nigrum (Black Currant) Seed Oil ........................................................................................................................ 7



Zea Mays (Corn) Oil ...................................................................................................................................................... 7

CARCINOGENICITY .......................................................................................................................................................... 7

CLINICAL ASSESSMENT OF SAFETY ............................................................................................................................ 8

Irritation/Sensitization/Allergenicity ................................................................................................................................. 8

Carthamus Tinctorius (Safflower) Oil ........................................................................................................................... 9



Oryza Sativa (Rice) Bran Oil ......................................................................................................................................... 9

Persea Gratissima (Avocado) Oil ................................................................................................................................... 9




Linum Usitatissimum (Linseed) Seed Oil ...................................................................................................................... 9

Ribes Nigrum (Black Currant) Seed Oil ...................................................................................................................... 10

Comedogenicity ............................................................................................................................................................... 10

Ribes Nigrum (Black Currant) Seed Oil ...................................................................................................................... 10

Case Studies ..................................................................................................................................................................... 10

Glycine Soja (Soybean) Oil ......................................................................................................................................... 10

Helianthus Annuus (Sunflower) Oil ............................................................................................................................ 10

Olea Europea (Olive) Fruit Oil .................................................................................................................................... 11

Persea Gratissima (Avocado) Oil ................................................................................................................................. 11

SUMMARY ......................................................................................................................................................................... 11

FIGURES AND TABLES ................................................................................................................................................... 14

Figure 2. Basic oil refinement flowchart.3 .................................................................................................................... 15

Table 2. Previously reviewed oil and fatty acid ingredients. ........................................................................................... 18

Table 3. Fatty acid composition. ...................................................................................................................................... 20

Table 4. Chemical properties. .......................................................................................................................................... 26


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Table 5. Frequency of use according to duration and exposure. ...................................... Error! Bookmark not defined. Table 6. Non-food, non-cosmetic uses of edible oils.3 ................................................................................................... 42

REFERENCES .................................................................................................................................................................... 48


1

INTRODUCTION

Vegetable oil and related edible seed oils have been safely consumed by humans for millennia. Because there is no

significant safety concern with these ingredients following oral exposure and their general biology is well characterized due to

extensive use in food materials, this safety assessment will focus solely on the basic chemistry, manufacturing/production, uses,

and irritation and sensitization data available on these oils as they are used in cosmetic ingredients. Various oils have been used on

the skin since antiquity. Initially used for anointing in religious ceremonies, oils and their components have long been used on the

skin for cosmetic purposes. The full list of ingredients this report covers, which includes oils, hydrogenated oils, unsaponifiables,

oil fatty acids, and simple salts, is found in Table 1. For the sake of brevity, the common name of the oil, when available, will be

used throughout this report. While a large number of oils derived from plants are included in this literature review, there is a

commonality in that they all are mixtures of triglycerides containing fatty acids and fatty acid derivatives, the safety of which in

cosmetics have been established.

This report includes cosmetic ingredients that have been previously reviewed by the Cosmetic Ingredient Review Expert

Panel. The ingredients, their conclusion, and published citations are found in Table 2. Previously reviewed fatty acids and

glyceryl triesters are also found in Table 2. This report excludes tree and ground nut oils, are covered in another safety

assessment.

CHEMISTRY

The group of ingredients characterized as fats and oils are the glyceryl esters of fatty acids (triglycerides) normally found

in plant tissues, including those which have been hydrogenated to reduce or eliminate unsaturation.1 Figure 1 is the general

structure of fats and oils. The raw oil may include plant sterols, pigments, glucosides, proteins, vitamins and impurities. The

extent to which these components are removed during processing varies. The available fatty acid compositions for the oils in this

report are found in Table 3. The available information on chemical properties and other constituents, including Food Chemicals

Codex specifications when provided, are found in Table 4.2

The percentage of chemical constituents in individual oil types is dependent on region where the oilseed plant is grown,

individual cultivars, and plant genetics.3 This is especially true in with rapeseed, where the erucic acid content varies from 1% to

58.6%. Low erucic acid rapeseed oil is also known as canola oil.

The nutritional content of these oils varies with oil type. For example, sunflower oil contains high levels of vitamins A,

D, and K, while palm oil is a rich source of vitamins A and E. Crude sunflower oil also has the highest content of vitamin E in the

form of α-tocopherol amongst vegetable oils.3


2

Processing

Oils used in cosmetics are probably produced using the same process used in the food industry. Depending on the source,

oil may be directly expressed from the source (seed or pulp) followed by solvent extraction. Bailey’s Industrial Oil and Fat

Products states that the removal of pigments and polar materials is mandatory for most cosmetic applications.4 The process used

for oil refining for foods may be adequate for this purpose, or additional steps may be required. Special refining methods to yield

colorless and odorless oils are used by the cosmetic industry and include proprietary adsorption chromatography and supercritical

fluid extractions.

The majority of the oils presented in this report are produced either from mechanical extraction or solvent extraction or a

hybrid of both methods, known as prepress solvent extraction.3 In solvent extraction, hexane is the most commonly used solvent

as it is economical and has low toxicity potential when compared to other solvents. Seeds that are rich in oil can be cold pressed to

extract oil without the use of solvents.5

Af ter the initial extraction by methods such as solvent extraction, the crude (degummed) oil is often refined.3 The first

step is treating the oil with caustic soda to neutralize free fatty acids, hydrolyze phosphatides, and remove some colored pigments

and unsaponifiable materials. Soap stock is usually a by-product of this step. The next step involves bleaching the neutralized oil

with activated earth to further absorb pigments. The last major step in refining oil is deodorizing, which removes all oxidative

cleavage products that impart odor or flavor to the oil. Deodorization also removes tocopherols, sterols, and other minor

constituents of free fatty acids and undesirable foreign materials. Figure 2 is a flowchart of the basic refinement process.

After deodorization, oils can be further processed by hydrogenation, which makes oil more resistant to oxidative and

thermal damage, and by winterization, where oil is slowly cooled to promote formation of crystals that cause cloudiness and

filtered to remove the crystals.

Cosmetic grade vegetable oils may include a physical refining step that involves heating crude vegetable oil under

vacuum.5 This step allows for the removal of volatile components such as color compounds, odor compounds, and free fatty acids,

which gives the refined oil a lighter color, less odor, and lower acid values.

Analytical Methods

According to Crevel et al., a validated analytical methodology for establishing the protein content of oil is needed.6

Impurities

Many edible oils are derived from foods that are recognized as potent food allergens. It has been shown that often an

individual that is allergic to a food will generally not react to the refined oil.6 It should be noted that while the Panel has found a

general lack of clinical effects for edible oils already reviewed,7-15 other researchers have raised concerns. Halsey et al. reported

that Lowry protein determinations of cold-pressed and refined sunflower oil found 2-8 µg/ml protein,16 while Zitouni et al.


3

reported trace amounts of protein in the refined oil.17 Olszewski et al. found 0.1-0.2 µg protein per g of peanut oil,18 while

Ramazzotti et al. reported finding IgE responsive residual proteins in peanut oil extracts.19 Porras et al. found soy protein is some

samples of soy oil, but not others.20 Awazuhara et al. reported 1.4-4.0 µg protein per 100 g of soy oil.21 Although Paschke et al.

found approximately 35 µg/ml protein content in refined soybean oil, no IgE-binding activity was detectable.22 The European

Medicines Agency (EMEA) Working Party on Herbal Medicinal Products concluded that soy and peanut products “should be

treated as allergenic unless they have an analytically-monitored non-allergenic specification and a safe maximum daily dose.”23

The EMEA found that threshold concentrations for induction of a protein contact dermatitis were not available and recommended

that “all medications for topical use containing soya or peanut products should be treated as allergenic.”

USE

Cosmetic

Oils are used in a wide variety of cosmetic products for their skin conditioning, occlusive, emollient, moisturizing and

other properties. A total of 124 of the 208 oil ingredients included in this safety assessment are reported to be used; 108 of the in-

use ingredients have never been reviewed by CIR, while 16 have been reviewed previously. For the ingredients being reviewed

for the first time, the frequency of use, as supplied to the Food and Drug Administration (FDA) by industry as part of the

Voluntary Cosmetic Registration Program (VCRP),24 and/or concentration of use, as supplied by industry in response to a Personal

Care Products Council (Council) survey,25,26 can be found in Table 5a. For the ingredients that have been reviewed previously, the

current and historical8,10,11,15,27-30 frequency and concentration of use is given in Table 5b. The 84 ingredients not currently

reported to be used are listed in Table 5c. Table 5d lists the 41 ingredients for which a concentration of use survey has not yet

been completed.

Sunflower seed oil has the greatest number of reported uses in cosmetic and personal care products, with a total of 1414.

Many other ingredients are used in an extensive number of formulations. For example, olive oil and soybean oil have 915 and 912

uses, respectively. Most of the in-use ingredients have uses in both leave-on and rinse-off product types, and many are used in

products that are applied around the eye or that can possibly be ingested. Some are used in products that involve mucous

membrane exposure, and a few are used in underarm deodorant formulations. Many of the products are used in formulations at

relatively high concentrations. Olive oil is used at up to 100%, avocado oil is used at up to 98%, sunflower seed oil at up to 96%,

and soybean oil at 95%.

The oil ingredients described in this report may be used in hair sprays, and effects on the lungs that may be induced by

aerosolized products containing these ingredients are of concern. The aerosol properties that determine deposition in the

respiratory system are particle size and density. The parameter most closely associated with deposition is the aerodynamic

diameter, da, defined as the diameter of a sphere of unit density possessing the same terminal settling velocity as the particle in


4

question. In humans, particles with an aerodynamic diameter of ≤ 10µm are respirable. Particles with a da from 0.1 - 10µm settle

in the upper respiratory tract and particles with a da < 0.1 µm settle in the lower respiratory tract.31,32

Particle diameters of 60-80 µm and ≥80 µm have been reported for anhydrous hair sprays and pump hairsprays,

respectively.33 In practice, aerosols should have at least 99% of their particle diameters in the 10 – 110 µm range and the mean

particle diameter in a typical aerosol spray has been reported as ~38 µm.34 Therefore, most aerosol particles are deposited in the

nasopharyngeal region and are not respirable.

None of the oils or their related counterparts described in this report were restricted from use in any way under the rules

governing cosmetic products in the European Union.35

Non-Cosmetic

The primary uses for edible oils are for cooking. Palm oil is the world's most widely consumed edible oil (41.7 million

metric tons), followed by soybean oil, rapeseed oil, sunflower seed oil, cottonseed oil, peanut oil, palm kernel oil, coconut oil, ,and

olive oil.3,36 Non-food, non-cosmetic uses for edible oils are found in Table 6.

ANIMAL TOXICOLOGY

OILS

Irritation, sensitization and phototoxicity data available were reviewed and are summarized below. Information from

previous CIR reports on edible oils is identified by italics. No information was found for some of the oils listed in this report.

Dermal Irritation/Sensitization/Phototoxicity

Adansonia Digitata Seed Oil [Baobab]

In an alternative to the Draize test, 100% baobab oil was tested for dermal irritation in a MatTek EpiDerm ™ MTT

viability assay.37 The MatTek EpiDerm™ tissue samples were incubated with 100 µl of the test material for 1, 4, or 24 h along

with the positive control material, 1% Triton X-100, which was incubated for 4 or 9 h, and the negative control, undosed tissues,

which were incubated for 4 h. After treatment, the viability of the tissues was determined with MTT uptake and conversion. The

positive control provided expected results. The test material was classified as non-irritating.

Carthamus Tinctorius (Safflower) Oil

Undiluted safflower oil was minimally irritating in a repeat open patch test using rabbits and was not a primary irritant

or sensitizer in a maximization study using guinea pigs15.

Gossypium Herbaceum (Cotton) Seed Oil

Cosmetic formulations containing 3.4-8.97% hydrogenated cottonseed oil were not irritating to rabbit skin.10


5

Elaeis Guineensis (Palm) Oil

Undiluted palm oil was practically non- to minimally irritating to rabbit skin.8 Palm oil, 5%, was non-allergenic in a

maximization study. A facial lotion containing 1.5% palm oil was not phototoxic in the phototoxicity yeast assay.

Olea Europea (Olive) Fruit Oil

Hartley and/or Himalayan guinea pigs were used to determine the sensitization potential of olive oil. 38 Single drops of a

USP-grade olive oil that had been stored in its original metal container for 10 yrs were applied to an area clipped free of hair on the

backs of 12 guinea pigs. (The composition of the oil was not determined.) Applications were made at 2-6 wk intervals over a

period of 5 mos. Four guinea pigs were treated similarly using store-bought virgin olive oil. None of the animals had a positive

reaction following the initial application of either oil. Using the 10-yr-old olive oil, 11 of 12 of the animals had a positive reaction

at some point during the study. Some, but not all, of these guinea pigs reacted consistently following the first positive reaction; 2

animals had only one positive reaction. Two guinea pigs in this group died by wk 16. In the group dosed with virgin olive oil, one

animal had a positive reaction at wk 2 and one animal had a positive reaction at wks 4 and 6.

Twenty-two guinea pigs sensitive to the 10-yr-old USP olive oil were used to determine cross-reactivity with the store-

bought virgin olive oil, another store-bought olive oil (not specified as virgin olive oil), corn oil, and peanut oil. The 5 oils were

applied simultaneously to the backs of the guinea pigs. Eighteen of the animals reacted to the virgin olive oil, and 18 reacted to the

other store-bought olive oil. (Overlap of these animals was not complete.) Cross-reactivity to corn or peanut oil was not observed.

The researchers then applied single drops of the unsaponifiable fraction of the 10-yr-old oil to 8 sensitized and 4 non-

sensitized guinea pigs. All of the sensitized animals reacted to the unsaponifiable fraction, while the non-sensitized animals did

not react.

Olive oil is used as a vehicle in the murine local lymph node assay (LLNA), an in vitro assay developed to assess a

chemical’s potential to induce allergic contact dermatitis in humans.39 The LLNA protocol states that the solvent/vehicle should

be selected on the basis of maximizing the test concentrations while producing a solution/suspension suitable for application of the

test substance. The recommended vehicle is acetone/olive oil (4:1 v/v).

Oryza Sativa (Rice) Bran Oil and Germ Oil

Undiluted rice bran oil was not irritating to rabbits, and in a guinea pig maximization study, no reactions were observed

when 55 was used at induction and 25 and 50% rice bran oil were used at challenge. 11 Rice germ oil was not a primary dermal

irr itant, and a rice bran oil/rice germ oil mixture, concentrations not stated, did not cause a contact allergy response. Undiluted

hydrolyzed rice protein was also not irritating or sensitizing. Undiluted rice bran oil and rice germ oil, ≤75%, were not

phototoxic or photosensitizing.

Sesamum Indicum (Sesame) Seed Oil


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Undiluted sesame oil was non- or minimally irritating to rabbit skin.30

Tr iticum Vulgare (Wheat) Germ Oil

Wheat germ oil, undiluted and at 2% in formulation, was non- to mildly irritating, and undiluted wheat germ oil was not

sensitizing to guinea pigs.13

Zea Mays (Corn) Oil

A group of 6 Hartley and/or Himalayan guinea pigs were used to determine the sensitization potential of store-bought

corn oil. 38 None of the animals had a positive reaction following the initial application. Two animals had positive reactions

following application at wks 4 and 6, while one animal had a positive reaction following application at wk 12.

Ocular Irritation

Adansonia Digitata Seed Oil [Baobab]

In an alternative to the Draize rabbit eye test, 100% baobab oil was tested for ocular irritation in a MatTek EpiOcular ™

MTT viability assay.37 The MatTek EpiOcular™ tissue samples were treated with 100 µl of the test material for 16, 64, or 256

minutes along with the positive control material, 0.3% Triton X-100, which was treated for 15 or 45 minutes, and the negative

control, tissue culture water, which was treated for 16 minutes. After treatment, the viability of the tissues was determined with

MTT uptake and conversion. The positive control provided expected results. The test material was classified as non-irritating.


Undiluted palm oil and cosmetic lotions and creams containing 1.5-2.0% palm oil were minimally irritating to the eyes of

rabbits, while one lotion containing 1.5% palm oil was moderately irritating.8 Hydrogenated palm oil suppositories were mildly

ir ritating to rabbit eyes.


Cosmetic formulations containing 3.4-12.3% hydrogenated cottonseed oil were mildly irritating to the eyes of rabbits.10

Lin um Usitatissimum (Linseed) Seed Oil

A mascara containing 9.4% linseed oil was tested for eye irritation potential in an in vitro study using neutral red release

(NRR), hen’s egg test on chorio-allantoic membrane (HET-CAM), and reconstituted human epithelial culture (REC) assays.40 For

the NRR assay, the test product was diluted at 0%, 5%, 15%, 25%, 35%, and 50% in mineral oil. The NR50 of the test product was

greater than 50% and the test product was considered slightly cytotoxic. In the HET-CAM assay, the score was 6.25 and the test

product was considered moderately irritating when applied under a 67.1% solution in mineral oil. Finally in the REC assay, the

cumulative simplified mean cytotoxicity index (SMCI) was calculated to be 0.25 and the test product was considered slightly

cytotoxic when applied under a 66.9% solution in mineral oil. Overall, the study concluded that the mascara containing 9.4%

linseed oil may be slightly irritating.


7


The ocular irritation potential of high purity olive oil was evaluated using in vivo and in vitro testing.41 In vivo, a Draize

test was conducted using New Zealand rabbits. (The number of animals used was not specified.) Undiluted olive oil was not an

ocular irritant in this test. Using human conjunctival epithelial cells in an in vitro study, olive oil did not induce cellular necrosis

or apoptosis.

Oryza Sativa (Rice) Bran and Rice Germ Oil

A mixture of rice bran oil and rice germ oil, concentrations not stated, were not irritating to rabbit eyes.11 Undiluted rice

bran oil was considered minimally irritating, and rice germ oil, concentration not stated, was not a primary irritant.

Ribes Nigrum (Black Currant) Seed Oil

A 50% dilution of an eye mask containing 0.2% black currant seed oil was tested in a HET-CAM assay.42 Two eye gels

with vitamin E at 50% were used as reference products. The average score was 2.00, where a mean score of 0-4.9 considered

“practically none” for irritation potential.


Undiluted sesame oil was non- to minimally irritating to rabbit eyes, and a lipstick containing 10-11% sesame oil was not

an ocular irritant.30

Tr iticum Vulgare (Wheat) Germ Oil

Undiluted wheat germ oil was, at most, a minimal ocular irritant, and 2% in a water emulsion was not irritating.13

Zea Mays (Corn) Oil

The ocular irritation potential of high purity corn oil was evaluated using in vivo and in vitro testing.41 In vivo, a Draize

test was conducted using New Zealand rabbits. (The number of animals used was not specified.) Undiluted corn oil was not an

ocular irritant in this test. Using human conjunctival epithelial cells in an in vitro study, corn oil did not induce cellular necrosis or

apoptosis.

CARCINOGENICITY

The safety of glycidol fatty acid esters in refined vegetable oils was assessed by IARC. Glycidol was determined to be a

Group2A (probably carcinogenic to humans) chemical while Glycidol Fatty Acid Esters was determined to be a Group 3 (not

classifiable as to carcinogenicity to humans) chemical.43,44

The Federal Institute for Risk Assessment in Germany released a summary of their initial evaluation of the assessment of

levels of glycidol fatty acid esters detected in refined vegetable fats.45 While acknowledging that the levels of glycidol that may be


8

released from glycidol fatty acid esters are not known, the evaluation noted that glycidol is classified as probably carcinogenic to

humans. The evaluation was based on findings of the German Chemical and Veterinary Test Agency (CVUA).

In a presentation by Weisshauer from the CVUA, the conversion of glycidol to 3-chloropropanediol was presented as an

artifact of the analytical method, and it appeared to be the 3-chloropropanediol that was detected its indicative of the presence of

glycidol.46 The levels of 3-chloropropanediol were negligible at the crude oil, degummed, neutralized, and bleached stages, but

levels were significant at the deodorized stage.

CLINICAL ASSESSMENT OF SAFETY

Edible oils are commonly believed to be safe for use on the skin.4 de Groot notes that no documentation exist to show that

high quality edible lipids cause adverse reactions in normal individuals (except for potential comedogenicity).47 Very few reports

of adverse reactions to cosmetic use of edible oils have been reported.

Irritation/Sensitization/Allergenicity

Many edible oils are derived from foods that are recognized as potent food allergens. It has been shown that often an

individual that is allergic to a food will generally not react to the refined oil.6 A prime example is peanut oil. While the safety of

peanut oil is not being addressed in this assessment, it is being discussed here to demonstrate that although a food might cause

allergic reactions, the oil usually does not. Peanuts are extremely allergenic to a large population, but reaction to the oil is rare. In

its safety assessment on peanut (Arachis hypogaea) oil, the Expert Panel noted that the major concern associated with allergic

reactions to peanuts is the protein.9 The protein does not partition into the refined oil, and therefore the oil is safe for use in

cosmetics. Crevel et al. also concluded that chemically refined peanut oil is safe for the majority of peanut allergic individuals.6

They stated that “as peanut is acknowledged to be one of the most potent food allergens, it is reasonable to extrapolate the

conclusions drawn up for peanut oil to other edible oils.” However, they concede that validated analytical methodology for

establishing the protein content of oil is needed.

In support of the conclusions stated earlier, Crevel et al. also examined the allergenicity of some other oils. Very few

instances of allergic reactions to other major edible oils have been reported. Even sesame oil, which differs from the other oils in

that it is used as a flavorant and therefore is not as refined and expected to contain significantly more protein that the other edible

oils, has had very few reports of allergic reaction. Additional studies demonstrating safety are summarized later in this section.16,48

Specific information on clinical dermal irritation and sensitization findings from previous CIR reports on edible oils are

described below and are identified by italics. New clinical irritation and sensitization data is summarized in Table 7.


9

Carthamus Tinctorius (Safflower) Oil

Cosmetic formulations containing 3-5% safflower oil were not irritating to humans in occlusive patch tests and were not

primary irritants or sensitizers in repeated insult patch tests.15


Palm oil, 15% in petrolatum or cosmetic formulations containing 1.0-2.0%, was not an irritant or sensitizer in clinical

studies.8 Bar soap flakes, tested at dilutions that contained ≤ 2.13% palm kernel oil, were not irritating or sensitizing.


In a clinical patch test, the irritation potential of a cosmetic formulation containing 3.4% hydrogenated cottonseed oil

was mildly low, and the severity of reaction to 10.4% hydrogenated cottonseed oil was acceptably low in a use study.10 Cosmetic

formulations containing 10.6-20.86% hydrogenated cottonseed oil were not irritating or sensitizing. Patients that were

hypersensitive to cottonseed proteins were not sensitive to cottonseed oil in a skin prick test.

Oryza Sativa (Rice) Bran Oil

Rice is generally regarded as hypoallergenic, although some case studies of allergic reactions to raw rice have been

reported.11 In clinical testing, formulations containing 1.04-8.0% rice bran oil were not irritating or sensitizing, and formulations

containing 1.04% rice bran oil were not photosensitizing. Hydrolyzed rice protein was not irritating to human subjects.

Persea Gratissima (Avocado) Oil

Avocado was not an irritant or sensitizers when human subjects were patch tested with cosmetic formulations containing

up to 10.7% avocado oil or in patch tests using 100% avocado oil.14


In clinical testing, undiluted sesame oil was not irritating.30 Cosmetic formulations containing 8-14.3% sesame oil were

non- to essentially non-irritating. Prophetic patch testing with formulations containing 10-11% sesame oil were not irritating with

or without UV light. Patients with contact allergy to sesame oil were patch tested, and most had positive reactions to sesamol,

sesamin, and sesamolin.

Triticum Vulgare (Wheat) Germ Oil

In clinical testing, wheat germ oil was not an irritant or a sensitizer.13

Ocular Irritation

Linum Usitatissimum (Linseed) Seed Oil

The ocular irritation potential of a mascara containing 9.4% linseed oil was tested in 33 female subjects for 4 weeks.49 Of

the 33 subjects, 16 were contact lens wearers and the remaining 17 were self-assessed sensitive eye non-contact lens wearers. One

subject dropped out of the study for non-treatment related reasons. Subjects were evaluated with subjective questionnaires


10

regarding ocular sensation following product use as well as with objective ophthalmic findings. Trace increases in palpebral

conjunctival irritation were observed in only one subject, but this result was thought to be non-treatment related by the study

investigators. No subjective irritation was reported and no adverse events were reported. The study concluded that the test

material was clinically safe for use by contact lens wearers and self-assessed sensitive eye non-contact wearers.


An in-use 4 week study was conducted on an eye mask that contained 0.2% black currant seed oil (undiluted) in 52

subjects.50 Subjects were evaluated by an ophthalmologist and a dermatologist at baseline and at the end of the study. No adverse

reactions were observed. The eye mask was considered ophthalmologist tested and safe for contact lens wearers.

Comedogenicity


A comedogenicity study of an eye mask containing 0.2% black currant seed oil (undiluted) was performed on 6

subjects.51 The test material was applied with occlusive patches. The average score was 0.00 comedones/cm2. The eye mask was

found to be non-comedogenic.

Case Studies

Glycine Soja (Soybean) Oil

Seven patients with a history of immediate hypersensitivity reaction after the ingestion of soybeans were enrolled in a

double-blind crossover study.48 The patients were first skin tested by the puncture method with a crude whole soybean extract, a

partially hydrogenated oil, a non-hydrogenated oil, and a cold-pressed soybean oil. Olive oil from a retailer was used as a negative

control. Since all 7 patients had negative skin tests to the oils and positive reactions to the crude soybean extract, they were

challenged orally with capsules of each of the oils in random order on 4 separate days. None of the patients reacted to the oral

challenges. The researchers remarked that while a reaction to the cold-pressed soybean oil did not occur in this study, cold-pressed

oils may contain soybean protein and should be avoided.

The sera from 4 patients with known allergy to soybean was used to examine the allergenicity of soy oil proteins.21

Neither the IgE nor the IgG4 in the sera reacted to protein in the soy oil.

Helianthus Annuus (Sunflower) Oil

Two cases were reported of patients having anaphylactic reactions following ingestion of sunflower seeds.16 No

reactions were seen upon oral or open challenge with refined or cold-pressed sunflower oils, both of which were shown to contain

detectable amounts of protein. However, in a case report of a woman who had been desensitized to mugwort (a member of the

Compositae family) pollen for a year, but then had an anaphylactic reaction to sunflower (also a member of the Compositae

family) seeds, it was found that she had a delayed positive reaction to sunflower oil in a skin prick test.52 Prick test results with 10


11

control subjects were negative. In an oral challenge test, a delayed reaction was again observed, with symptoms occurring 2.25-8

h after administration.


Throughout the literature, it is stated that sensitization to olive oil is considered rare. Case reports have been described,

however, and generally involved patients with venous eczema, some type of dermatitis or lesion, or an occupational exposure.

Patch testing with olive oil produced positive reactions in most of these cases, and these results were usually regarded as

allergenic. The concentrations of olive oil tested were not always given, but when stated, test concentrations giving positive

results, ranged from 30-100%. In some cases, the constituents of olive oil were tested as well, but the results of that testing were

negative.53-60

Kränke et al. investigated whether the reactions to olive oil were contact sensitization or irritation, using open and

occlusive testing. They concluded that olive oil presented as a weak irritant rather than a contact sensitizer in the few case studies

they observed. The capacity to produce an irritant result was increased using occlusive conditions.61 Zipprich and Hauser

remarked that components capable of inducing an irritant reaction can form if the olive oil isn’t stored properly.62

Persea Gratissima (Avocado) Oil

A case study was reported in which a female subject had dermatitis around the eyes and earlobes.63 Patch testing with her

sunscreen resulted in positive results. In subsequent patch testing of the individual ingredients, a positive reaction to undiluted

avocado oil, but not to the active ingredient, was observed. Twenty controls subjects were used, and reactions to avocado oil were

not seen.


A case study was reported in which a woman applied a Chinese ointment containing sesame oil, resulting in pruritic

erythema, papules, and vesicles. 64 Patch testing was performed with the ointment and with the individual ingredients, including

undiluted sesame oil. Both the ointment and sesame oil produced positive reactions on days 2, 3, 4, and 11. The other components

did not cause a reaction. Results were negative in patch testing of sesame oil using 20 healthy subjects.

SUMMARY

The oils derived from vegetable and fruit plants are composed of mono-, di-, and triglycerides, free fatty acids and other

minor components, including natural antioxidants and fat-soluble vitamins. The percentage of chemical constituents and

nutritional content of individual oil types is dependent on region where the oil plant is grown, individual cultivars, and plant

genetics. Oils used in cosmetics are likely produced in the same manner as those used in the food industry. Oils may be expressed


12

through mechanical or solvent extraction. The oils may undergo further refining to remove pigments, odors, unsaponifiable

materials, and other undesirables.

It has been shown that often an individual that is allergic to a food will generally not react to the refined oil. The CIR

Expert Panel has found a general lack of clinical effects for edible oils that they have already reviewed; however, other researchers

have raised concerns about the presence of residual proteins oils, such as peanut and soy. These ingredients may also contain

aflatoxins, a metabolic products of certain molds that are carcinogenic to humans. The FDA action level for aflatoxin in foods is

20 ppb.

Of the oils described in this report, sunflower seed oil has the most reported uses in cosmetic and personal care products

with a total of 1414 and is used at a maximum concentration of 96%. Oils are used in a wide variety of cosmetic products,

including use in hair spray and other aerosolized products. None of the oils or the related counterparts described in this report

were restricted from use in the European Union.

Oils not summarized in the animal toxicity section or clinical studies section of this report had no available data for

review.

In dermal irritation studies in animals, Adansonia Digitata seed oil [baobab], hydrogenated cottonseed oil, rice bran oil,

and rice germ oil were not irritating. Undiluted safflower oil was minimally irritating in rabbits, but it was not a primary irritant in

guinea pigs. Undiluted palm oil, sesame oil, and wheat germ oil were practically non-irritating to minimally irritating in rabbits.

Safflower oil, palm oil, rice bran oil, rice germ oil, and wheat germ oil were non-sensitizing in animal studies. Rice bran oil, rice

germ oil, and palm oil were not phototoxic in animals studies.

In animal ocular studies, Adansonia Digitata seed oil [baobab], olive oil, rice germ oil, black currant seed oil, 10-11%

sesame seed oil, 2% wheat germ oil, and corn oil were non-irritating. Undiluted palm oil and palm oil at 2% were minimally

irritating to rabbit eyes. Hydrogenated palm oil and 3.4% - 12.3% hydrogenated cottonseed oil were considered mildly irritating.

In a HET-CAM study, 9.4% linseed oil was slightly irritating. Undiluted rice bran oil and undiluted wheat germ oil were

minimally irritating to eyes, while undiluted sesame oil was non- to minimal ocular irritants.

Glycidol and glycidol fatty acid esters, possible constituents in refined vegetable oils, were determined to be Group 2A

(probably carcinogenic to humans) and Group 3 (not classifiable as to carcinogenicity to humans) chemicals, respectively, by

IARC.

Edible oils are believed to be safe for use on the skin and very few reports of adverse reactions have been reported. The

proteins that are responsible for allergenic responses in individuals with food allergies do not partition into refined oils.


13

In previously reviewed oils, safflower oil, palm oil, hydrogenated cottonseed oil, rice bran oil, avocado oil, sesame oil,

and wheat oil were non-irritating and/or non-sensitizing in human studies. In many of the oils found in this report, no irritation

and/or sensitization reactions were observed in human repeated insult patch tests.

In clinical studies, 0.2% black currant seed and 9.4% linseed oil were not ocular irritants. Black currant seed oil at 0.2%

was also non-comedogenic. Cases of contact allergy have been reported for soybean oil, sunflower oil, olive oil, avocado oil, and

sesame seed oil.


14

FIGURES AND TABLES

OCR

O

H2C

HC OCR'

O

H2C OCR"

O

-OCR, -OCR', and -OCR" may be the same or diff erent f atty acid radicals.

Figure 1. General structure of fats and oils.1


15

-

Crude Oil

Degummed Oil Lecithin Sludge

Alkali Refined Oil Soap Stock

Salad Oil

Cooking Oil Salad and

Cooking Oil Partially

Hydrogenated Oil

Other Fatty Oil

Shortening Stock

Blended Oils

Margarine Stock

Bleached Oil

Salad Oil

Water

Alkali

Deodorization

Deodorization

Deodorization

Deodorization

Deodorization

Deodorization

Activated Earth

H2, Catalyst

Winterization & Deodorization

Figure 2. Basic oil refinement flowchart.3


16

Tab

le 1

. Edi

ble

oils

and

thei

r de

rivat

ives

.*

Veg

eta

ble

(O

lus)

Oil

(CA

S N

o. 6

8956

-68

-3)

Hel

ian

thu

s A

nnuu

s (S

un

flow

er)

Se

ed O

il (C

AS

No.

800

1-2

1-6

) B

rass

ica

Na

pus

See

d O

il [R

apes

eed

]

Hyd

roge

an

ted

Veg

eta

ble

Oil

(CA

S N

o. 6

833

4-2

8-1

) H

elia

nth

us

Ann

uus

(Su

nflo

we

r) S

eed

Oil

Un

sap

onifi

able

s B

rass

ica

Ole

race

a A

cep

ha

la S

eed

Oil

[Ka

le]

Maj

or O

ils

Hyd

roge

na

ted

Sun

flow

er S

eed

Oil

Bra

ssic

a O

lera

cea

Ita

lica

(B

rocc

oli)

See

d O

il B

rass

ica

Cam

pes

tris

(R

ap

esee

d)

See

d O

il (C

AS

No.

800

2-1

3-9

) S

un

flow

er S

eed

Aci

d (

CA

S N

o. 8

4625

-38

-7)

Ca

mel

ina

Sat

iva

See

d O

il [F

als

e F

lax]

Bra

ssic

a C

amp

estr

is (

Ra

pes

eed

) O

il U

nsa

pon

ifiab

les

Ole

a E

uro

pea

(O

live)

Fru

it O

il (C

AS

No.

80

01-2

5-0

) H

ydro

gen

ate

d C

am

elin

a S

ativ

a S

eed

Oil

Hyd

roge

na

ted

Ra

pes

eed

Oil

(CA

S N

o. 8

4681

-71

-0)

Hyd

roge

na

ted

Oliv

e O

il C

am

ellia

Jap

onic

a S

eed

Oil

Pot

ass

ium

Rap

esee

da

te

Hyd

roge

an

ted

Oliv

e O

il U

nsa

pon

ifiab

les

Ca

mel

lia K

issi

See

d O

il [T

ea]

Rap

esee

d A

cid

O

live

Aci

d (

CA

S N

o. 9

2044

-96

-7)

Ca

mel

lia O

leife

ra S

eed

Oil

[Tea

See

d]

Sod

ium

Ra

pes

eed

ate

O

lea

Eu

rop

aea

(O

live)

Hu

sk O

il H

ydro

gen

ate

d C

am

ellia

Ole

ifera

Se

ed O

il

Can

ola

Oil

(CA

S N

o. 8

002

-13

-9; 1

209

62-0

3-0

) O

lea

Eu

rop

aea

(O

live)

Oil

Un

sap

onifi

ab

les

(CA

S N

o. 1

567

98-1

2-8

) C

am

ellia

Sin

ensi

s S

eed

Oil

Can

ola

Oil

Un

sap

onifi

ab

les

Pot

ass

ium

Oliv

ate

(CA

S N

o. 6

815

4-7

7-8

) C

aric

a P

apa

ya S

eed

Oil

[Pap

aya

] H

ydro

gen

ate

d C

an

ola

Oil

Sod

ium

Oliv

ate

(C

AS

No.

647

89-8

8-6

) C

ary

oca

r B

rasi

lien

se F

ruit

Oil

[Peq

ui]

Car

tham

us T

inct

oriu

s (S

affl

ower

) Se

ed O

il (C

AS

No.

800

1-23

-8)

Ory

za S

ativ

a (R

ice)

Bra

n O

il (C

AS

No.

685

53-8

1-1;

846

96-3

7-7)

C

hen

opod

ium

Qui

noa

See

d O

il [Q

uin

oa]

Hyd

roge

na

ted

Sa

fflow

er S

eed

Oil

Ory

za S

ativ

a (R

ice)

Ger

m O

il C

itru

llus

Lan

atu

s (W

ate

rmel

on)

Se

ed O

il

Pot

ass

ium

Sa

fflo

we

rate

R

ice

Bra

n A

cid

(CA

S N

o. 9

3165

-33-

4)

Citr

us

Au

ran

tifol

ia (

Lim

e) S

eed

Oil

Sa

fflo

wer

Aci

d H

ydro

gen

ate

d R

ice

Bra

n O

il C

itru

s A

ura

ntif

olia

(Li

me)

See

d O

il U

nsa

pon

ifiab

les

Sod

ium

Sa

fflow

era

te

Ory

za S

ativ

a (

Ric

e) S

eed

Oil

H

ydro

gen

ate

d L

ime

Se

ed O

il

Ela

eis

Gui

neen

sis

(Pal

m)

Oil

(CA

S N

o. 8

002-

75-3

) Se

sam

um I

ndic

um (

Sesa

me)

See

d O

il (C

AS

No.

800

8-74

-0)

Hyd

roge

na

ted

Lim

e S

eed

Oil

Un

sap

onifi

ab

les

Ela

eis

Gui

neen

sis

(Pal

m) K

erne

l Oil

(CA

S N

o. 8

023-

79-8

) H

ydro

gena

ted

Sesa

me

Seed

Oil

Citr

us

Au

ran

tium

Du

lcis

(O

ran

ge)

Se

ed O

il

Hyd

roge

nate

d P

alm

Oil

(CA

S N

o. 8

033-

29-2

; 685

14-7

4-9)

Se

sam

um I

ndic

um (

Sesa

me)

Oil

Uns

apon

ifia

bles

C

itru

s A

ura

ntiu

m D

ulc

is (

Ora

nge

) S

eed

Oil

Un

sap

onifi

ab

les

Hyd

roge

nate

d P

alm

Ker

nel O

il (C

AS

No.

689

90-8

2-9;

845

40-0

4-5)

So

dium

Ses

ames

eeda

te

Hyd

roge

na

ted

Ora

nge

See

d O

il

Pa

lm K

ern

el A

cid

Ses

am

um

Ind

icu

m (

Ses

am

e) S

eed

But

ter

Hyd

roge

na

ted

Ora

nge

See

d O

il U

nsa

pon

ifiab

les

Ela

eis

Gu

inee

nsi

s (P

alm

) B

utte

r (C

AS

No.

80

02-7

5-3

) Z

ea M

ays

(Cor

n) O

il (C

AS

No.

800

1-30

-7)

Citr

us

Gra

ndis

(G

rap

efru

it) S

eed

Oil

Ela

eis

Ole

ifera

Ke

rnel

Oil

Zea

May

s (C

orn)

Ger

m O

il C

itru

s G

rand

is (

Gra

pef

ruit)

See

d O

il U

nsa

pon

ifiab

les

Ela

eis

(Pa

lm)

Oil

Zea

May

s (C

orn)

Oil

Uns

apon

ifia

bles

C

itru

s P

ara

dis

i (G

rap

efru

it) S

eed

Oil

Pa

lm A

cid

Cor

n A

cid

(CA

S N

o. 6

8308

-50-

9)

Hyd

roge

na

ted

Gra

pef

ruit

See

d O

il

Hyd

roge

na

ted

Pa

lm A

cid

Pot

assi

um C

orna

te (

CA

S N

o. 6

1789

-23-

9)

Hyd

roge

na

ted

Gra

pef

ruit

See

d O

il U

nsa

pon

ifia

ble

s P

ota

ssiu

m P

alm

ate

M

inor

Oils

C

itru

s Li

mon

(Le

mon

) S

eed

Oil

(CA

S N

o. 8

508

5-2

8-5

)

Pot

ass

ium

Hyd

roge

na

ted

Pa

lmat

e A

ctin

idia

Chi

nen

sis

(Kiw

i) S

eed

Oil

Coi

x La

crym

a-J

obi (

Job

's T

ears

) S

eed

Oil

Pot

ass

ium

Pa

lm K

ern

ela

te

Ad

an

son

ia D

igita

ta O

il [B

aob

ab]

Cra

mb

e A

bys

sin

ica

See

d O

il [A

bys

sin

ian

Mu

sta

rd]

Sod

ium

Hyd

roge

na

ted

Pa

lma

te

Ad

an

son

ia D

igita

ta S

eed

Oil

Cuc

um

is S

ativ

us

(Cuc

um

ber

) S

eed

Oil

(CA

S N

o. 7

095

5-2

5-8

) S

odiu

m P

alm

ate

(CA

S N

o. 6

179

0-7

9-2

) H

ydro

gen

ate

d A

da

nso

nia

Dig

itata

See

d O

il C

ucu

rbita

Pep

o (P

um

pki

n)

See

d O

il (C

AS

No.

801

6-4

9-7

)

Sod

ium

Pa

lm K

ern

ela

te (

CA

S N

o. 6

1789

-89

-7)

Am

ara

nth

us

Hyp

och

ond

riacu

s S

eed

Oil

[Am

ara

nth]

H

ydro

gen

ate

d P

um

pkin

See

d O

il

Gly

cin

e S

oja

(S

oyb

ean

) O

il (C

AS

No.

80

01-2

2-7

) A

rctiu

m L

ap

pa S

eed

Oil

[Bu

rdoc

k]

Cyn

ara

Ca

rdun

culu

s S

eed

Oil

[Art

icho

ke]

(CA

S N

o. 9

230

29

-60

-1)

Gly

cin

e S

oja

(S

oyb

ean

) O

il U

nsa

pon

ifia

ble

s (C

AS

No.

91

770

-67

-1)

Arg

an

ia S

pin

osa

Ker

ne

l Oil

[Arg

an

] E

ute

rpe

Ole

race

a F

ruit

Oil

[Aca

i]

Hyd

roge

na

ted

Soy

bea

n O

il (C

AS

No.

80

16-7

0-4

) H

ydro

gen

ate

d A

rga

nia

Sp

inos

a K

ern

el O

il F

raga

ria A

na

na

ssa

(S

tra

wb

erry

) S

eed

Oil

So

y A

cid

(C

AS

No.

683

08

-53

-2)

Ast

roca

ryu

m M

uru

mu

ru S

eed

Bu

tter

[Mu

rum

uru

] F

raga

ria C

hilo

ensi

s (S

tra

wb

erry

) S

ee

d O

il

Pot

ass

ium

Soy

ate

S

odiu

m A

stro

cary

um

Mu

rum

uru

ate

F

raga

ria V

esca

(S

tra

wb

erry

) S

eed

Oil

Sod

ium

Soy

ate

A

ven

a S

ativ

a (

Oat

) K

ern

el O

il

Fra

garia

Virg

inia

na

(S

tra

wb

erry

) S

eed

Oil

Gos

sypi

um H

erba

ceum

(Cot

ton)

See

d O

il (C

AS

No.

800

1-29

-4)

Ba

ssia

But

yra

cea

See

d B

utte

r G

arc

inia

Ind

ica

See

d B

utte

r [K

oku

m]

Cot

tons

eed

Aci

d (C

AS

No.

683

08-5

1-0)

B

ass

ia L

atif

olia

See

d B

utte

r [M

ahw

a]

Gu

izot

ia A

bys

sin

ica

See

d O

il [R

amtil

]

Hyd

roge

nate

d C

otto

nsee

d O

il (C

AS

No.

683

34-0

0-9)

B

ora

go O

ffici

na

lis S

eed

Oil

[Bor

age

] (C

AS

No.

225

234

-12

-8)

Hip

pop

ha

e R

ham

noi

des

Oil

[Sea

-Buc

kth

orn]

* p

revi

ousl

y re

vie

wed

ingr

edie

nts

are

in

bold

and

ital

ics


17

Tab

le 1

. Edi

ble

oils

and

thei

r de

rivat

ives

.*

Hip

pop

ha

e R

ham

noi

des

Fru

it O

il [S

ea-B

uckt

hor

n]

Hyd

roge

na

ted

Pa

ssifl

ora

Edu

lis S

eed

Oil

Hyd

roge

na

ted

Ra

spb

erry

See

d O

il

Hip

pop

ha

e R

ham

noi

des

See

d O

il [S

ea-B

uckt

hor

n]

Per

illa

Ocy

moi

des

See

d O

il [P

erill

a]

Scl

eroc

ary

a B

irrea

See

d O

il [M

aru

la]

Irvi

ngi

a G

ab

onen

sis

Ker

ne

l Bu

tter

[Dik

a] (

CA

S N

o. 1

922

30

-28

-7)

Per

sea

Gra

tissi

ma

(Avo

cado

) O

il (C

AS

No.

802

4-32

-6)

Sily

bu

m M

aria

num

See

d O

il [T

his

tle]

Lim

na

nth

es A

lba

(M

ead

owfo

am

) S

eed

Oil

(CA

S N

o. 1

5306

5-4

0-8

)

Hyd

roge

na

ted

Avo

cad

o O

il S

ola

nu

m L

ycop

ersi

cum

(T

oma

to)

See

d O

il

Hyd

roge

na

ted

Mea

dow

foa

m S

eed

Oil

P

erse

a G

ratis

sim

a (A

voca

do)

But

ter

Sol

an

um

Lyc

oper

sicu

m (

Tom

ato

) F

ruit

Oil

Lin

um

Usi

tatis

sim

um

(Li

nse

ed)

Se

ed O

il (C

AS

No.

800

1-2

6-1

) P

erse

a G

ratis

sim

a (A

voca

do)

Oil

Un

sap

onifi

ab

les

(CA

S N

o. 9

177

0-

40

-0)

Th

eob

rom

a C

aca

o (C

ocoa

) S

eed

But

ter

(CA

S N

o. 8

002

-31

-1)

Lin

seed

Aci

d (

CA

S N

o. 6

8424

-45

-3)

Sod

ium

Avo

cad

oate

S

odiu

m C

ocoa

But

tera

te

Luffa

Cyl

ind

rica

See

d O

il [L

uffa

] P

luke

net

ia V

olu

bilis

See

d O

il [S

ach

a In

chi]

Th

eob

rom

a G

ran

difl

oru

m S

eed

Bu

tter

[Cup

ua

cu]

(CA

S N

o.

394

236

-97

-6)

Lup

inu

s A

lbu

s S

eed

Oil

[Wh

ite L

up

ine]

P

runu

s A

rmen

iaca (A

pric

ot)

Ker

nel

Oil

(CA

S N

o. 7

286

9-6

9-3

) S

odiu

m T

heo

bro

ma

Gra

ndi

floru

m S

eed

ate

Lup

inu

s A

lbu

s O

il U

nsap

onifi

able

s H

ydro

gen

ate

d A

pric

ot K

ern

el O

il T

orre

ya N

uci

fera

See

d O

il [K

aya

]

Lyci

um

Ba

rba

rum

See

d O

il [G

oji B

erry

] H

ydro

gen

ate

d A

pric

ot K

ern

el O

il U

nsa

pon

ifia

ble

s T

ritic

um V

ulga

re (

Whe

at)

Ger

m O

il (C

AS

No.

800

6-95

-9;

6891

7-73

-7)

Man

gife

ra In

dic

a (

Man

go)

See

d O

il P

runu

s A

rmen

iaca

(A

pric

ot)

Ker

nel

Oil

Un

sap

onifi

able

s H

ydro

gen

ate

d W

hea

t G

erm

Oil

Man

gife

ra In

dic

a (

Man

go)

See

d B

utte

r P

runu

s A

viu

m (

Sw

eet

Ch

erry

) S

eed

Oil

Hyd

roge

na

ted

Wh

eat

Ger

m O

il U

nsa

pon

ifiab

les

Sod

ium

Man

gose

eda

te

Pru

nus

Dom

estic

a S

eed

Oil

[Pru

ne/

Plu

m]

Trit

icu

m A

estiv

um

(W

hea

t) G

erm

Oil

Mor

ind

a C

itrifo

lia S

eed

Oil

[Non

i] P

runu

s P

ersi

ca (

Pea

ch)

Ker

ne

l Oil

(CA

S N

o. 8

002

-78

-6; 8

023

-98

-1)

Trit

icu

m V

ulg

are

(W

hea

t) G

erm

Oil

Un

sap

onifi

able

s

Mor

inga

Ole

ifera

Se

ed O

il [B

en]

Hyd

roge

na

ted

Pea

ch K

ern

el O

il W

hea

t G

erm

Aci

d (

CA

S N

o. 6

893

8-3

2-9

)

Mor

inga

Pte

ryg

osp

erm

a S

eed

Oil

P

uni

ca G

ran

atu

m S

eed

Oil

[Pom

egra

nte]

V

acc

iniu

m C

orym

bos

um

(B

lueb

erry

) S

eed

Oil

Oen

oth

era

Bie

nni

s (E

veni

ng

Prim

rose

) O

il H

ydro

gen

ate

d P

unic

a G

ran

atu

m S

eed

Oil

Va

ccin

ium

Ma

croc

arp

on (

Cra

nber

ry)

See

d O

il H

ydro

gen

ate

d E

ven

ing

Prim

rose

Oil

Pyr

us

Ma

lus

(Ap

ple

) S

eed

Oil

Hyd

roge

na

ted

Cra

nber

ry S

eed

Oil

Org

ibn

ya C

ohun

e S

eed

Oil

[Coh

un

e]

Rib

es N

igru

m (

Bla

ck C

urr

ant)

See

d O

il (C

AS

No.

976

76-1

9-2

) V

acc

iniu

m M

yrtil

lus

See

d O

il [B

ilber

ry]

(CA

S N

o. 1

161

921

-09

-0)

Orb

ign

ya O

leife

ra S

eed

Oil

[Bab

ass

u] (

CA

S N

o. 9

107

8-9

2-1

) H

ydro

gen

ate

d B

lack

Cu

rra

nt S

eed

Oil

Va

ccin

ium

Viti

s-Id

aea

See

d O

il [L

igo

nb

erry

]

Orb

ign

ya S

pec

iosa

Ker

ne

l Oil

[Ba

bass

u]

Rib

es R

ub

rum

(C

urr

ant)

See

d O

il V

an

illa

Pla

nifo

lia F

ruit

Oil

[Van

illa

] (C

AS

No.

802

4-0

6-4

) B

aba

ssu

Aci

d R

osa

Can

ina

Fru

it O

il [D

og R

ose]

V

itis

Vin

ifera

(G

rap

e) S

eed

Oil

(CA

S N

o. 8

024

-22

-4)

Pot

ass

ium

Bab

ass

uat

e H

ydro

gen

ate

d R

osa

Ca

nina

Fru

it O

il S

odiu

m G

rap

esee

da

te

Sod

ium

Ba

bass

uat

e R

ubu

s C

ham

aem

oru

s S

eed

Oil

[Clo

udb

erry

] H

ydro

gen

ate

d G

rap

esee

d O

il

Pa

ssifl

ora

Edu

lis S

eed

Oil

[Pa

ssio

n F

ruit]

(C

AS

No.

87

676

-26

-1)

Rub

us

Ida

eus

(Ra

spb

erry

) S

eed

Oil

* p

revi

ousl

y re

vie

wed

ingr

edie

nts

are

in

bold

and

ital

ics


18

Tab

le 2

. Pre

viou

sly

revi

ewed

oil

and

fatty

aci

d in

gred

ient

s.

Ingr

edie

nts

Pub

licat

ion

Dat

e C

oncl

usio

n

Oil

Ingr

edie

nts

Ca

rth

am

us

Tin

ctor

ius

(Sa

fflo

wer

) S

eed

Oil

(CA

S N

o. 8

001

-23

-8)

JAC

T 4

(5):

17

1-1

97,

198

5;

Re-

revi

ew

ed,

not

reo

pen

ed IJ

T 2

5(2

):1

-89

, 20

06

Sa

fe

Ela

eis

Gu

inee

nsi

s (P

alm

) O

il (C

AS

No.

80

02-7

5-3

)

IJT

19

(S2

):7

-28,

200

0 S

afe

E

laei

s G

uin

een

sis

(Pa

lm)

Ke

rnel

Oil

(CA

S N

o. 8

023

-79

-8)

Hyd

roge

na

ted

Pa

lm O

il (C

AS

No.

803

3-2

9-2

; 685

14-7

4-9

)

Hyd

roge

na

ted

Pa

lm K

ern

el O

il (C

AS

No.

68

990

-82

-9; 8

454

0-0

4-5

)

Gos

syp

ium

Her

ba

ceu

m (

Cot

ton

) S

eed

Oil

(CA

S N

o. 8

001

-29

-4)

IJT

20

(S2

):21

-29

, 200

1 S

afe

C

otto

nsee

d A

cid

(C

AS

No.

683

08-5

1-0

)

Hyd

roge

na

ted

Cot

ton

seed

Oil

(CA

S N

o. 6

833

4-0

0-9

)

Ory

za S

ativ

a (

Ric

e) B

ran

Oil

(CA

S N

o. 6

855

3-8

1-1

; 846

96

-37

-7)

IJT

25

(S2

):91

-120

, 20

06

Sa

fe

Ory

za S

ativ

a (

Ric

e) G

erm

Oil

Ric

e B

ran

Aci

d (C

AS

No.

93

165

-33

-4)

Ses

am

um

Ind

icu

m (

Ses

am

e) S

eed

Oil

(CA

S N

o. 8

008

-74

-0)

JAC

T 1

2(3

):2

61-2

77, 1

993;

A

men

ded

Fin

al R

epor

t, 20

09

Sa

fe

Hyd

roge

na

ted

Ses

am

e S

eed

Oil

Ses

am

um

Ind

icu

m (

Ses

am

e) O

il U

nsa

pon

ifiab

les

Sod

ium

Ses

am

esee

da

te

Zea

Ma

ys (

Cor

n)

Oil

(CA

S N

o. 8

001

-30

-7)

Fin

al R

epor

t, 2

008

S

afe

Z

ea M

ays

(C

orn

) G

erm

Oil

Zea

Ma

ys (

Cor

n)

Oil

Un

sap

onifi

able

s

Cor

n A

cid

(CA

S N

o. 6

830

8-5

0-9

)

Pot

ass

ium

Cor

nat

e (C

AS

No.

617

89

-23

-9)

Per

sea

Gra

tissi

ma

(Avo

cad

o) O

il (C

AS

No.

80

24-3

2-6

) JE

PT

4(4

):93

-10

3, 1

980

; R

e-re

vie

wed

, n

ot r

eop

ened

IJT

22

(1):

1-3

5, 2

003

S

afe

Trit

icu

m V

ulg

are

(W

hea

t) G

erm

Oil

(CA

S N

o. 8

006

-95

-9; 6

891

7-7

3-7

) JE

PT

4(4

):33

-45

, 19

80;

Re-

revi

ew

ed,

not

reo

pen

ed IJ

T 2

2(1

):1

-35

, 20

03

Sa

fe

Fat

ty A

cids

Ara

chid

onic

Aci

d (C

AS

No.

506

-32

-1)

JAC

T 1

2 (

5):

481

-55

9, 1

993

Insu

ffici

ent d

ata

Hyd

roxy

stea

ric A

cid

(C

AS

No.

106

-14

-9)

IJT

18

(S1

):1

-10,

199

9 S

afe

Lau

ric A

cid

(C

AS

No.

143

-07

-7)

JAC

T 6

(3):

32

1-4

01,

198

7;

Re-

revi

ew

ed,

not

reo

pen

ed IJ

T 2

5(2

):1

-89

, 20

06

Sa

fe

Myr

istic

Aci

d (

CA

S N

o. 5

44-6

3-8

)

Ole

ic A

cid

(C

AS

No.

11

2-8

0-1

)

Pa

lmiti

c A

cid

(C

AS

No.

57

-10

-3)

Ste

aric

Aci

d (

CA

S N

o. 5

7-1

1-4

)


19

Ta

ble

2.

Pre

viou

sly

revi

ew

ed o

il a

nd fa

tty

aci

d in

gred

ien

ts (

cont

inu

ed)

.

I ngr

edie

nts

Pub

licat

ion

Dat

e C

oncl

usio

n

Gly

cery

l Tri

este

rs

Tril

au

rin

IJT

20

(S

4):

61

-94,

200

1 S

afe

Tria

rach

idin

T

ribeh

enin

Tric

ap

rin

Tric

ap

rylin

Trie

ruci

n T

rihep

tan

oin

Trih

epty

lun

dec

anoi

n

Trii

son

onan

oin

Trii

sop

alm

itin

Trii

sost

earin

Tril

inol

ein

Trim

yris

tin

Trio

cta

noi

n T

riole

in

Trip

alm

itin

Trip

alm

itole

in

Trir

icin

olei

n T

riste

arin

Triu

ndec

an

oin

Gly

cery

l Tria

cety

l Hyd

roxy

stea

rate

Gly

cery

l Tria

cety

l Ric

inol

eate

G

lyce

ryl S

tea

rate

Dia

ceta

te


20

Tab

le 3

. Fat

ty a

cid

com

posi

tion.

Fat

ty A

cids

C

orn

Oil28

,65,

66 *

C

otto

n S

eed

Oil10

O

live

Oil3

Pal

m

Oil8

Pal

m K

erne

l O

il8 R

apes

eed

Oil3

Ful

ly

Hyd

roge

nate

d R

apes

eed

Oil2

Can

ola

Oil2

Saf

flow

er

See

d O

il15,6

7 S

esam

e S

eed

Oil7,

30

Cap

roic

(C

6)

0

.3

Cap

rylic

(C

8)

4

.4

Cap

ric (

C10

)

3.7

Laur

ic (

C12

)

0.2

4

8.3

Myr

istic

(C

14)

0.1

- 1

.7

2 T

race

1

.1

15.

6

< 1

.0

< 0

.2

<

0.5

Myr

isto

leic

(C

14:1

)

Pal

miti

c (C

16)

8-1

2; 8

-16.

5 2

1 7

.5 -

20

44

7.8

1

.5 -

3

3-5

.0

< 6

.0

2 7

.0 -

12.

0

Pal

mito

leic

(C

16:1

) 0

.2 -

1.6

0.3

- 3

.5

0.1

< 1

.0

<

0.5

Hep

tade

cano

ic (

C17

:0)

Ste

aric

(C

18)

2.5

- 4

.5; 0

-4

Tra

ce

0.5

- 3

.5

4.5

2

0.7

- 1

.3

38

-42

< 2

.5

3

.5 -

6.0

Ole

ic (

C18

:1)

19

– 49

; 20

-43

30

53

- 86

3

9.2

15.

1 1

2.1

- 57

.4

1 >

50

26

35

- 50

Lino

leic

(C

18:2

) 3

4 –

62; 5

0-6

6 4

5 3

.5 -

20

10.

1 2

.7

11.

4 -

22.1

<

1.0

<

40

.0

68

35

- 50

Lino

leni

c (C

18:3

) 0

-2

0

- 1

.5

0.4

8.3

- 1

2.5

< 1

4 T

race

<

1.0

Ara

chid

ic (

C20

) 1

T

race

T

race

0

.4

8

-10

.0

< 1

.0

Tra

ce

<1

.0

Eic

osen

oic

(C20

:1)

1

5

.6 -

3.1

<

1.0

<

2.0

<0

.5

Eic

osad

ieno

ic (

C20

:2)

Beh

enic

(C

22)

Tra

ce

42

-50

< 0

.5

<

0.5

Eru

cic

(C22

:1)

1 -

58.

6 <

1.0

<

2.0

Doc

osad

ieno

ic (

C22

:2)

Doc

osah

exae

noic

(C

22:6

)

Lign

ocer

ic (

C24

)

T

race

1

-2.0

<

0.2

Ara

chid

onic

(C

20:4

n6)

Ara

chid

ontr

ieno

ic

Oth

ers

0

.2

< C

14 =

<

0.1

; C2

4:1

=

< 0

.2

Tra

ce o

f co

mp

onen

ts

bel

ow

C1

4

Ole

ic/L

inol

eic

Sat

urat

ed, G

ener

al

*Sh

ad

owin

g id

entif

ies

pre

viou

sly

revi

ew

ed in

gred

ien

ts.


21

Tab

le 3

. F

atty

aci

d co

mpo

sitio

n (c

ontin

ued.

)

Fat

ty A

cids

S

oybe

an

Oil3

Sun

flow

er

See

d O

il3 A

cai

Oil68

A

mar

anth

O

il69

Ap

ricot

K

erne

l Oil

3 A

rtic

hoke

O

il70

Avo

cado

O

il3 B

abas

su

Oil3

Ben

O

il71

Cam

elin

a (F

alse

F

lax)

See

d O

il72

Cap

roic

(C

6)

Cap

rylic

(C

8)

4

to

8

Cap

ric (

C10

)

4 t

o 8

Laur

ic (

C12

)

44

- 47

Myr

istic

(C

14)

1

5 -

20

Tra

ce

Myr

isto

leic

(C

14:1

)

Pal

miti

c (C

16)

5

.0 -

7.2

2

2 1

9 -

20

Sm

all

qu

antit

y 1

2 1

3-1

7 6

to

9 9

.3

7.8

Pal

mito

leic

(C

16:1

) 2

3 -

5.1

Hep

tade

cano

ic (

C17

:0)

Ste

aric

(C

18)

2

.0 -

6.5

2

3

3

3 t

o 5

7.4

2

.96

Ole

ic (

C18

:1)

11.

5 -

60.0

1

4.7

- 37

.2

60

22

- 26

25

67

-72

10

to 1

2 6

5.7

16.

77

Lino

leic

(C

18:2

) 2

5 -

63.1

5

1.5

- 73

.5

12

46

- 50

6

0 1

0 to

12

1 t

o 3

23.

08

Lino

leni

c (C

18:3

) 2

.9 -

12.

1 T

race

- 0

.3

Tra

ce

3

1.2

Ara

chid

ic (

C20

) 0

.3 -

1

2.5

Eic

osen

oic

(C20

:1)

1

1.99

Eic

osad

ieno

ic (

C20

:2)

Beh

enic

(C

22)

8

.6

Eru

cic

(C22

:1)

2

.8

Doc

osad

ieno

ic (

C22

:2)

Doc

osah

exae

noic

(C

22:6

)

Lign

ocer

ic (

C24

)

Tra

ce

Ara

chid

onic

(C

20:4

n6)

Ara

chid

ontr

ieno

ic

Oth

ers

3

.4

Ole

ic/L

inol

eic

90

-93

Sat

urat

ed, G

ener

al

12

- 13

.5


22

Tab

le 3

. F

atty

aci

d co

mpo

sitio

n (c

ontin

ued.

)

Fat

ty A

cids

Coc

oa

See

d B

utte

r3 C

ohun

e O

il3 C

ranb

erry

S

eed

Oil73

C

ucum

ber

Oil74

Cup

uacu

S

eed

But

ter75

G

rape

S

eed

Oil3

Lins

eed

Oil3

Ma

ngo

See

d O

il3 **

Ma

rula

O

il76

Mea

dow

foam

S

eed

Oil3

Cap

roic

(C

6)

Cap

rylic

(C

8)

7.5

Cap

ric (

C10

) 6

.5

Laur

ic (

C12

)

46.

5

Myr

istic

(C

14)

1

6

T

race

Myr

isto

leic

(C

14:1

) P

alm

itic

(C16

) 2

4-2

9 9

.5

4.0

- 6

9

.0 -

13

7.2

7

-9.5

5

.5

5.0

-8

9 t

o 12

Pal

mito

leic

(C

16:1

) 0

.1

0.0

5 -

0.15

Hep

tade

cano

ic (

C17

:0)

0.2

Ste

aric

(C

18)

34

-36

3

6.0

- 9

3

0.8

3.5

-5.5

3

.5

33

-48

5 t

o 8

Ole

ic (

C18

:1)

30

-40

10

20

- 24

1

4 -

20

43.

9 1

4-4

4 1

9.1

35

-50

70

- 78

Lino

leic

(C

18:2

) 2

.4

1 3

2 -

37

60

- 68

4

.6

46

-74

15.

3 4

.0-8

4

.0 -

7.0

Lino

leni

c (C

18:3

) 3

0 -

35

< 1

T

race

5

7 0

.1 -

0.6

Ara

chid

ic (

C20

) 1

1 1

.0-7

0

.3 -

0.7

Eic

osen

oic

(C20

:1)

0.1

- 0

.5

52

- 77

Eic

osad

ieno

ic (

C20

:2)

Beh

enic

(C

22)

Eru

cic

(C22

:1)

0.1

- 0

.5

8.0

- 2

9

Doc

osad

ieno

ic (

C22

:2)

7.0

- 2

0

Doc

osah

exae

noic

(C

22:6

) Li

gnoc

eric

(C

24)

Ara

chid

onic

(C

20:4

n6)

Ara

chid

ontr

ieno

ic

Oth

ers

Ole

ic/L

inol

eic

Sat

urat

ed, G

ener

al

**A

s M

an

go K

ern

el F

at


23

Tab

le 3

. F

atty

aci

d co

mpo

sitio

n (c

ontin

ued.

)

Fat

ty A

cids

M

urum

uru

See

d B

utte

r77

Pea

ch

Ker

nel

Oil78

P

erill

a O

il3 Q

uino

a S

eed

Oil79

R

amtil

/Nig

er

Oil3

Ric

e G

erm

O

il11

Stra

wbe

rry

See

d O

il80

***

Wat

erm

elon

S

eed

Oil81

W

heat

Ger

m

Oil13

,27

Bao

bab

Oil82

,83

Cap

roic

(C

6)

Cap

rylic

(C

8)

1.8

5

Cap

ric (

C10

) 1

.85

Laur

ic (

C12

) 4

7.46

Myr

istic

(C

14)

26

0.2

6.9

2

Myr

isto

leic

(C

14:1

)

Pal

miti

c (C

16)

6.2

8 2

.0 -

7

9

.9 -

11

5.0

-13

9.2

8

8.0

- 1

3.0

1

1.0

- 16

1

8-3

0

Pal

mito

leic

(C

16:1

) 0

.1

4.4

1 <

1.0

1

Hep

tade

cano

ic (

C17

:0)

Ste

aric

(C

18)

2.6

5 0

.5 -

3.5

0.7

- 0

.8

2.0

-11

7.9

1

8.0

- 1

2.0

1.0

- 6

2

-8

Ole

ic (

C18

:1)

12.

56

55

- 70

1

4-2

3 2

2 -

24.5

6

.0-4

0 1

7.81

1

6.5

- 19

.5

15.

0 -

30.0

8

.0 -

30

30

-40

Lino

leic

(C

18:2

) 2

.87

22

- 33

1

6 5

0.2

- 56

4

5-7

7 1

6.22

2

8.5

- 41

.5

55.

0 -

65.0

4

4 -

65

24

-34

Lino

leni

c (C

18:3

) <

1

63

-70

5.4

- 7

1

5.56

3

3.5

- 36

.5

< 1

.0

4.0

- 1

0 1

-3

Ara

chid

ic (

C20

) 0

.7

3.0

8 <

1.0

Eic

osen

oic

(C20

:1)

<

1.0

Eic

osad

ieno

ic (

C20

:2)

Beh

enic

(C

22)

<

1.0

Eru

cic

(C22

:1)

Doc

osad

ieno

ic (

C22

:2)

Doc

osah

exae

noic

(C

22:6

)

< 2

.0

Lign

ocer

ic (

C24

) 2

ma

x

Ara

chid

onic

(C

20:4

n6)

5

.48

Ara

chid

ontr

ieno

ic

5.2

1

Oth

ers

5

.5 -

8.5

<

1.0

0 -

1.2

C20

-22

S

atu

rate

d a

cid

s

Ole

ic/L

inol

eic

Sat

urat

ed, G

ener

al

6.0

-12

***R

epor

ted

as

Fra

garia

An

ana

ssa

(Str

aw

ber

ry)

Se

ed O

il.


24

Tab

le 3

. F

atty

aci

d co

mpo

sitio

n (c

ontin

ued.

)

Fat

ty A

cids

R

ice

Bra

n O

il84

Che

rry

Ker

nel

Oil85

,86

Arg

an

Oil87

,88

Bor

age

Oil89

,90

Cam

ellia

O

leife

ra

See

d O

il91,9

2 P

apay

a S

eed

Oil93

,94

Lim

e S

eed

Oil95

,96

Ora

nge

See

d O

il97,9

8 G

rape

frui

t S

eed

Oil99

,100

Pum

pki

n S

eed

Oil10

1,10

2

Cap

roic

(C

6)

Cap

rylic

(C

8)

Cap

ric (

C10

)

Laur

ic (

C12

) 1

.5

Myr

istic

(C

14)

1 1

Myr

isto

leic

(C

14:1

)

Pal

miti

c (C

16)

14

4-1

0 1

0-1

5 9

-13

6.1

-15

8-1

8 2

0-3

0 1

4-2

2 1

8-3

0 1

0-1

6

Pal

mito

leic

(C

16:1

) 2

Hep

tade

cano

ic (

C17

:0)

Ste

aric

(C

18)

2 1

-4

5-6

.5

3-5

0

.8-2

2

-6

3-8

2

-6

2-8

3

-7

Ole

ic (

C18

:1)

45

23

-55

45

-55

10

-22

72

-87

60

-77

20

-38

26

-35

20

-38

18

-38

Lino

leic

(C

18:2

) 3

4 3

0-5

5 2

8-3

6 3

3-4

6 5

.3-1

4.3

3

-25

30

-45

35

-45

30

-48

40

-62

Lino

leni

c (C

18:3

) 1

13

18

-25

0.8

5

-15

2-6

2

-6

1

Ara

chid

ic (

C20

) 2

2 0

.5

Eic

osen

oic

(C20

:1)

2-6

2

Eic

osad

ieno

ic (

C20

:2)

Beh

enic

(C

22)

Eru

cic

(C22

:1)

1-3

.5

Doc

osad

ieno

ic (

C22

:2)

Doc

osah

exae

noic

(C

22:6

)

Lign

ocer

ic (

C24

)

Ara

chid

onic

(C

20:4

n6)

Ara

chid

ontr

ieno

ic

Oth

ers

Ele

oste

aric

(C

18:3

con

j) =

1

0%

α-L

inol

enic

(C

1 8:3

) =

0

.4%

; γ-L

inol

enic

=

1-3

.5%

α-L

inol

enic

(C

1 8:3

) =

2

%;

Ole

ic/L

inol

eic

Sat

urat

ed, G

ener

al


25

Tab

le 3

. F

atty

aci

d co

mpo

sitio

n (c

ontin

ued.

)

Fat

ty A

cids

Cra

nber

ry

See

d O

il103,

104

Eve

ning

P

rimro

se

Oil10

5,10

6 P

lum

O

il107,

108

Bla

ckcu

rran

t S

eed

Oil10

9,11

0 R

ed R

aspb

erry

S

eed

Oil11

1,11

2 M

orin

ga

Oil11

3,11

4

Cap

roic

(C

6)

Cap

rylic

(C

8)

Cap

ric (

C10

) La

uric

(C

12)

Myr

istic

(C

14)

Myr

isto

leic

(C

14:1

) P

alm

itic

(C16

) 5

-5.4

4

-10

4-9

6

-10

2-2

.3

5-9

5-9P

alm

itole

ic (

C16

:1)

1 1

.5-3

Hep

tade

cano

ic (

C17

:0)

Ste

aric

(C

18)

1 2

-4

3 1

-4

0.9

-1

3-8

Ole

ic (

C18

:1)

24

5-1

2 6

0-8

0 9

-16

10.

9-1

1 6

5-8

0

Lino

leic

(C

18:2

) 3

5 6

0-8

5 1

5-2

5 4

0-5

0 5

2.6

-53

1.5

-5

Lino

leni

c (C

18:3

) 1

31.

9-3

2 1

-1.5

Ara

chid

ic (

C20

) 1

2-5

Eic

osen

oic

(C20

:1)

3 2

.5-4

Eic

osad

ieno

ic (

C20

:2)

Beh

enic

(C

22)

1 8

Eru

cic

(C22

:1)

1 3

Doc

osad

ieno

ic (

C22

:2)

Doc

osah

exae

noic

(C

22:6

) Li

gnoc

eric

(C

24)

Ara

chid

onic

(C

20:4

n6)

Ara

chid

ontr

ieno

ic

Oth

ers

α-L

inol

enic

(C

18:3

) =

3

4-3

5%

α-L

inol

enic

(C

1 8:3

) =

1%

γ-L

inol

enic

= 7

-1

2%

α-L

inol

enic

(C

1 8:3

) =

11

-1

7%

γ-L

inol

enic

=

11-

14%

S

tea

ridon

ic

(18

:4)

= 2

-2

.5%

Ole

ic/L

inol

eic

Sat

urat

ed, G

ener

al


26

T

able

4. C

hem

ical

pro

pert

ies.

Pro

pert

ies

and

Con

stitu

ents

C

anol

a O

il2 C

otto

nsee

d O

il2,3

Oliv

e O

il3 P

alm

Oil2,

3 P

alm

Ker

nel O

il2,3

Rap

esee

d O

il3

App

eara

nce

Ligh

t ye

lllo

w o

il D

ark

red

-bro

wn

oil

Alm

ost

colo

rless

to

yello

w,

gre

enis

h, o

r b

row

n in

col

or

Pa

le y

ello

w t

o d

eep

or

an

ge in

col

or

Nea

rly c

olo

rless

Spe

cific

gra

vity

0

.914

-0.9

18

0.9

21-0

.925

(4

0◦C

)

Ref

ract

ive

inde

x

1.4

65-1

.467

(4

0◦C)

1.4

69-1

.484

1

.453

-1.4

58 (

40◦C

)

Iod

ine

valu

e 1

10-1

26

90

-113

6

4-8

8; r

efin

ed 7

5-9

4 4

4-5

8 1

4-3

3 8

1-1

12

Sap

onifi

catio

n va

lue

178

-193

1

80-1

98

185

-212

; ref

ined

184

-1

86

195

-205

2

45-2

55

168

-192

Per

oxid

e va

lue

(meq

/kg)

1

0 m

ax

10

ma

x 2

0 m

ax

(ref

ined

) 1

0 m

ax

10

ma

x

Mel

ting

poin

t (◦C

) 2

5-5

0 2

5-3

0

Uns

apon

ifiab

le m

atte

r (%

) 1

.5 m

ax

1.5

ma

x 0

.6-1

.2; 1

.5 m

ax

refin

ed

0.2

-0.8

1

.5 m

ax

0.5

- 2

Fre

e fa

tty a

cids

(%

) 0

.05

ma

x (a

s ol

eic

aci

d)

0.1

ma

x (a

s ol

eic

aci

d)#

# 0

.6-1

.4; 0

.3 m

ax

refin

ed 0

.1 m

ax

(as

olei

c ac

id);

0

.09

(as

pa

lmiti

c a

cid

)

0.1

ma

x (a

s ol

eic

acid

);

0.0

7 m

ax

(as

lau

ric

aci

d)

1

Lead

(m

g/kg

) 0

.1 m

ax

0.1

ma

x 0

.1 m

ax

0.1

mg/

kg m

ax

Aci

d va

lue

Pro

pert

ies

and

Con

stitu

ents

H

ydro

gena

ted

Rap

esee

d O

il2 S

afflo

wer

Oil2

Soy

bean

Oil2,

3 S

unflo

wer

Oil2,

3 A

pric

ot O

il3

Av o

cado

Oil3

App

eara

nce

Wh

ite w

axy

sol

id

Ligh

t ye

llow

oil

Ligh

t a

mb

er o

il Li

ght

am

ber

oil

Spe

cific

gra

vity

0

.894

-0.8

99 (

60◦C

) 0

.923

0

.910

-0.9

16

Ref

ract

ive

inde

x

1.4

597

-1.4

745

(a

t 25◦C

) 1

.467

2-1

.47

22

1.4

61-1

.465

Iod

ine

valu

e 4

ma

x 1

35-1

50

120

.9-1

51.4

1

28-1

44

81

-123

7

1-9

5

Sap

onifi

catio

n va

lue

188

-194

1

91

177

-198

Per

oxid

e va

lue

(meq

/kg)

2

.0 m

ax

10

ma

x 1

0 m

ax

10

ma

x

Mel

ting

poin

t (◦C

) 0

Uns

apon

ifiab

le m

atte

r (%

) 1

.5 m

ax

0.3

-0.6

0

.3-0

.5

Fre

e fa

tty a

cids

(%

) 2

.0 m

ax

(as

olei

c ac

id)

0.1

ma

x (a

s ol

eic

acid

) 0

.05

-0.7

0

.1 m

ax

(as

olei

c ac

id)

Lead

(m

g/kg

) 0

.1 m

ax

0.1

ma

x 0

.1 m

ax

0.1

ma

x

Aci

d va

lue


27

T

able

4. C

hem

ical

pro

pert

ies

(con

tinue

d).

Pro

pert

ies

and

Con

stitu

ents

B

abas

su O

il3 C

o coa

Oil3

Cra

nber

ry S

eed

Oil3,

73

Gra

pe S

eed

Oil3

Lins

eed

Oil3

Ma

ngo

Oil3

App

eara

nce

Ligh

t gr

een

P

ale

ye

llo t

o iv

ory

crea

m c

olor

Spe

cific

gra

vity

0

.916

-0.9

18 (

15◦C

) 0

.950

-0.9

98

0.9

23

0.9

1-0

.93

0.9

27-0

.931

(2

0◦C

) 0

.91

Ref

ract

ive

inde

x

1.4

49-1

.451

(4

0◦C)

1.4

53-1

.458

1

.470

-1.4

76

1.4

786

-1.4

815

1

.456

Iod

ine

valu

e 1

4-1

8 3

5-4

0 1

50.1

1

25-1

43

170

-204

3

2-9

3

Sap

onifi

catio

n va

lue

247

-251

1

90-2

00

176

-206

1

89-1

96

190

-195

Per

oxid

e va

lue

(meq

/kg)

<

15

Mel

ting

poin

t (◦C

) 3

3.5

0 3

4-4

3

Uns

apon

ifiab

le m

atte

r (%

) 0

.5-1

.5

0.8

-2.9

Fre

e fa

tty a

cids

(%

) 5

Lead

(m

g/kg

)

Aci

d va

lue

Pro

pert

ies

and

Con

stitu

ents

M

urum

uru

But

ter

3,77

P

each

Ker

nel O

il3,78

R

amtil

/Nig

er O

il3

Stra

wbe

rry

See

d O

il3,80

W

ater

mel

on S

eed

Oil3,

81

Bao

bab

Oil82

,83

App

eara

nce

Pa

le b

row

n w

axy

sol

id

at

room

tem

per

atu

re

Pa

le y

ello

w (

refin

ed)

Pa

le y

ello

w w

ith a

b

luis

h ti

nt

Ligh

t go

lden

P

ale

to

gold

en y

ello

w

liqui

d P

ale

ye

llow

Spe

cific

gra

vity

0

.890

-0.9

10 (

25◦C

) 0

.910

-0.9

20 (

20◦C

) re

fined

0

.910

-0.9

28

0.9

5 0

.893

0-0

.91

66

Ref

ract

ive

inde

x

1.4

67-1

.471

1

.466

8

Iodi

ne v

alue

1

5 m

ax

90

-115

(re

fined

) 1

26-1

39

113

-123

6

5-9

5

Sap

onifi

catio

n va

lue

270

-350

1

80-1

95

193

-195

1

90-2

10

Per

oxid

e va

lue

(meq

/kg)

2

0.0

ma

x 5

.0 m

ax

(ref

ined

) <

15

< 5

.0

5.0

-10

Mel

ting

poin

t (◦C

) 2

5- 3

7

Uns

apon

ifiab

le m

atte

r (%

) 0

.5-1

Fre

e fa

tty a

cids

(%

) 1

2.56

(a

s ol

eic

aci

d)

0.4

-3

< 5

.0 (

as

olei

c ac

id)

2.0

ma

x (a

s ol

eic

aci

d)

Lead

(m

g/kg

)

Aci

d va

lue


28

Tab

le 4

. Che

mic

al p

rope

rtie

s (c

ontin

ued)

.

Pro

pert

ies

and

Con

stitu

ents

R

ice

Bra

n O

il84,1

15

Che

rry

Ker

nel

Oil85

,86

Cor

n O

il65

,66

Arg

an O

il87,8

8 B

orag

e O

il89,9

0 C

amel

lia O

leife

ra

See

d O

il91,9

2

App

eara

nce

Ligh

t go

lden

ye

llow

C

lea

r lig

ht

yello

w

Cle

ar,

brig

ht

gold

en

yello

w

Yel

low

C

lea

r, p

ale

ye

llow

-go

lden

C

lea

r, p

ale

ye

llow

or

“wa

ter

wh

ite”

Spe

cific

gra

vity

0

.916

-0.9

22 (

15.

5◦C)

0.9

05-0

.925

(2

0◦C)

0.9

20-0

.928

(1

5.5◦C

) 0

.908

-0.9

18 (

20◦C

) 0

.918

-0.9

28 (

20◦C

)

Ref

ract

ive

inde

x

1.4

70-1

.473

(2

0◦C)

1.4

63-1

.480

(2

0◦C)

1.4

72-1

.476

(2

0◦C)

1.4

74-1

.479

(2

0◦C)

Iod

ine

valu

e 9

2-1

15

90

-115

1

03-1

28

95

130

-155

8

0-9

4

Sap

onifi

catio

n va

lue

180

-195

1

05-1

35

185

-195

1

84-1

94

188

-196

Per

oxid

e va

lue

(meq

/kg)

1

0.0

ma

x 1

0.0

ma

x 1

0.0

ma

x 1

0.0

ma

x 1

0.0

ma

x 1

0.0

ma

x

Mel

ting

poin

t (◦C

)

Uns

apon

ifiab

le m

atte

r (%

) 1

.5 m

ax

Fre

e fa

tty a

cids

(%

) 1

.0 (

as

olei

c a

cid

) 0

.5%

ma

x

Lead

(m

g/kg

) A

cid

valu

e 1

.0 m

ax

0.2

ma

x 3

-4

1.0

ma

x 1

.0 m

ax

Pro

pert

ies

and

Con

stitu

ents

P

apay

a S

eed

Oil

93,9

4 Li

me

See

d O

il95,9

6 O

rang

e S

eed

Oil97

,98

Gra

pefr

uit S

eed

Oil99

,100

Pum

pki

n S

eed

Oil10

1,10

2 C

ranb

erry

See

d O

il103,

104

App

eara

nce

Pa

le y

ello

w

Cle

ar

yello

w

Cle

ar,

ligh

t ye

llow

C

lea

r ye

llow

D

ark

gre

en

Spe

cific

gra

vity

0

.910

-0.9

20 (

20◦C

)

Ref

ract

ive

inde

x

1.4

66-1

.475

(2

0◦C)

Iod

ine

valu

e 6

5-1

00

90

-110

8

0-1

25

110

-330

1

40-1

80

Sap

onifi

catio

n va

lue

185

-200

1

74-1

97

170

-200

Per

oxid

e va

lue

(meq

/kg)

1

0.0

ma

x 5

.0 m

ax

5-1

0 5

-10

5.0

ma

x 5

.0 m

ax

Mel

ting

poin

t (◦C

)

Uns

apon

ifiab

le m

atte

r (%

) 1

.5

Fre

e fa

tty a

cids

(%

) 0

.8-3

0

.5 (

as

olei

c a

cid

) 1

.5 (

as

olei

c)

1.0

(a

s ol

eic

aci

d)

Lead

(m

g/kg

) A

cid

valu

e 1

.0 m

ax

0.8

ma

x 1

.0 m

ax

2.0

ma

x


29

Tab

le 4

. Che

mic

al p

rope

rtie

s (c

ontin

ued)

.

Pro

pert

ies

and

Con

stitu

ents

E

veni

ng P

rimro

se

Oil10

5,10

6 P

lum

Oil10

7,10

8 B

lack

curr

ant S

eed

Oil10

9,11

0 R

ed R

aspb

erry

S

eed

Oil11

1,11

2 M

orin

ga O

il11

3,11

4

App

eara

nce

Ligh

t ye

llow

Spe

cific

gra

vity

0

.920

-0.9

30 (

20◦C

) 0

.908

(2

0◦C

)

Ref

ract

ive

inde

x

1.4

75-1

.480

(2

0◦C)

Iod

ine

valu

e 1

45-1

65

90

-108

1

45-1

85

175

-195

Sap

onifi

catio

n va

lue

180

-195

1

80-2

00

192

Per

oxid

e va

lue

(meq

/kg)

1

0.0

ma

x 1

0.0

ma

x 1

-10

5.0

ma

x 1

0.0

Mel

ting

poin

t (◦C

)

Uns

apon

ifiab

le m

atte

r (%

)

Fre

e fa

tty a

cids

(%

) 2

.0 m

ax

(as

olei

c a

cid

) 0

.2

1.5

ma

x (a

s ol

eic

aci

d)

2.0

ma

x (a

s ol

eic

acid

)

Lead

(m

g/kg

) A

cid

valu

e 1

-2

3


30

Tab

le 5

a. F

requ

ency

of u

se a

ccor

ding

to d

urat

ion

and

expo

sure

. N

R =

Not

rep

orte

d t

o V

CR

P o

r C

ounc

il. N

S =

Not

yet

su

rve

yed

.

No.

of

Use

s (2

010)

C

onc.

of

Use

(2

010)

(%)

No.

of

Use

s (2

010)

C

onc.

of

Use

(2

010)

(%)

No.

of

Use

s (2

010)

C

onc.

of

Use

(2

010)

(%)

No.

of

Use

s (2

010)

Con

c. o

f U

se (

2010

) (%

)

No.

of

Use

s (2

010)

C

onc.

of

Use

(2

010)

(%)

No.

of

Use

s (2

010)

C

onc.

of

Use

(2

010)

(%)

Veg

etab

le (

Olu

s) O

il

Hyd

roge

nate

d V

eget

able

Oil

Bra

ssic

a C

ampe

stris

(R

apes

eed)

See

d O

il H

ydro

gena

ted

Rap

esee

d O

il C

anol

a O

il C

anol

a O

il U

nsap

onifi

able

s

Tot

als

165

0.00

05-3

1 45

7 0.

0004

-60

27

0.00

7-17

1

0.3-

4 13

2 0.

0002

-73

NR

0.

001

Dur

atio

n of

Use

Le

ave

-On

135

0

.000

5-1

1 4

39

0.0

005

-60

23

0.0

07-1

7 N

R

0.3

-4

112

0

.002

-73

NR

N

R

Rin

se O

ff

30

0.0

02-3

1 1

8 0

.000

4-8

4

0.1

-1

1 N

R

20

0.0

2-3

3 N

R

0.0

001

Exp

osur

e T

ype

Eye

Are

a 1

1 0

.01

-11

102

0

.008

-49

2 N

R

NR

2

3 0

.002

-0.0

3 N

R

NR

P

oss

ible

Ing

est

ion

74

0.0

3-1

1 2

16

0.8

-60

1 9

NR

N

R

62

0.3

-70

NR

N

R

Inha

latio

n 1

0.0

005

-0.0

2 1

3 N

R

NR

N

R

NR

1

0.0

002

-17

NR

N

R

De

rma

l Co

nta

ct

143

0

.000

5-3

1 4

50

0.0

05-6

0 2

7 0

.007

-17

1 0

.3-4

1

13

0.0

002

-73

NR

N

R

De

odo

ran

t (U

nde

rarm

) N

R

---

NR

N

R

NR

N

R

NR

N

R

NR

N

R

NR

N

R

Ha

ir -

No

n-C

olor

ing

2 0

.02

-2

2 0

.000

5-0

.09

NR

0

.1

NR

N

R

19

0.0

06-2

4 N

R

0.0

01

Ha

ir -

Co

lorin

g 1

8 --

- N

R

0.0

004

-1

NR

N

R

NR

N

R

NR

N

R

NR

N

R

Nai

l 1

2 1

0.2

N

R

NR

N

R

NR

N

R

5 N

R

NR

M

ucou

s M

em

bra

ne

1 0

.03

-2

2 2

-4

1 N

R

NR

N

R

2 0

.02

-1

NR

N

R

Ba

th P

rodu

cts

2 0

.002

-0.0

2 N

R

0.5

N

R

NR

N

R

NR

1

1-3

3 N

R

NR

B

aby

Pro

duct

s 1

---

NR

N

R

NR

N

R

NR

N

R

NR

N

R

NR

N

R

H

ydro

gena

ted

Can

ola

Oil

Pal

m K

erne

l Aci

d E

laei

s O

leife

ra K

erne

l Oil

Pal

m A

cid

Pot

assi

um P

alm

ate

Pot

assi

um P

alm

Ker

nela

te

Tot

als

3 N

R

72

0.2-

12

5 N

R

33

1-17

5

0.3-

3 7

0.3-

30

Dur

atio

n of

Use

Le

ave

-On

2 N

R

3 N

R

NR

N

R

1 N

R

NR

N

R

NR

N

R

Rin

se-O

ff

1 N

R

69

0.2

-12

5 N

R

32

1-1

7 5

0.3

-3

7 0

.3-3

0 E

xpos

ure

Typ

e

Eye

Are

a N

R

NR

N

R

NR

N

R

NR

N

R

NR

N

R

NR

N

R

NR

P

oss

ible

Ing

est

ion

NR

N

R

NR

N

R

NR

N

R

NR

N

R

NR

N

R

NR

N

R

Inha

latio

n N

R

NR

N

R

NR

N

R

NR

1

NR

N

R

NR

N

R

NR

D

erm

al C

ont

act

3

NR

7

1 0

.2-1

2 N

R

NR

3

3 1

-17

5 0

.3-3

7

0.3

-30

De

odo

ran

t (U

nde

rarm

) N

R

NR

N

R

NR

N

R

NR

N

R

NR

N

R

NR

N

R

NR

H

air

- N

on

-Col

orin

g N

R

NR

1

NR

2

NR

N

R

NR

N

R

NR

N

R

NR

H

air

- C

olo

ring

NR

N

R

NR

N

R

3 N

R

NR

N

R

NR

N

R

NR

N

R

Nai

l N

R

NR

N

R

NR

N

R

NR

N

R

NR

N

R

NR

N

R

NR

M

ucou

s M

em

bra

ne

NR

N

R

64

0.2

-3

NR

N

R

31

1-4

2

0.3

-3

1 0

.3-3

0 B

ath

Pro

duct

s N

R

NR

N

R

NR

N

R

NR

N

R

NR

N

R

NR

N

R

NR

B

aby

Pro

duct

s N

R

NR

N

R

NR

N

R

NR

N

R

NR

N

R

NR

N

R

NR


31

Tab

le 5

a. F

requ

ency

of u

se a

ccor

ding

to d

urat

ion

and

expo

sure

. (co

ntin

ued)

NR

= N

ot r

epor

ted

to

VC

RP

or

Cou

ncil.

NS

= N

ot y

et s

urv

eye

d.

N

o. o

f U

ses

(201

0)

Con

c. o

f U

se

(201

0) (%

) N

o. o

f U

ses

(201

0)

Con

c. o

f U

se

(201

0) (%

) N

o. o

f U

ses

(201

0)

Con

c. o

f U

se

(201

0) (%

) N

o. o

f U

ses

(201

0)

Con

c. o

f U

se

(201

0) (%

) N

o. o

f U

ses

(201

0)

Con

c. o

f U

se

(201

0) (%

) N

o. o

f U

ses

(201

0)

Con

c. o

f U

se

(201

0) (%

)

Sod

ium

Pal

mat

e S

odiu

m P

alm

Ker

nela

te

Gly

cine

Soj

a (S

oybe

an)

Oil

Gly

cine

Soj

a (S

oybe

an)

Oil

Uns

apon

ifiab

les

Hyd

roge

nate

d S

oybe

an O

il H

elia

nthu

s A

nnuu

s (S

unflo

wer

) S

eed

Oil

Tot

als

212

3-68

19

4 12

-44

912

0.00

02-9

5 12

0.

0001

-0.2

36

0.

001-

42

1414

0.

0000

07-9

6 D

urat

ion

of U

se

Le

ave

-On

7 N

R

10

NR

7

18

0.0

005

-95

12

0.0

001

-0.2

3

3 0

.001

-39

105

4 0

.000

2-9

6 R

inse

Off

205

3

-68

184

1

2-4

4 1

94

0.0

002

-95

NR

N

R

3 0

.05

-42

360

0

.000

007

-92

Exp

osur

e T

ype

Eye

Are

a

NR

N

R

NR

N

R

53

0.0

4-2

N

R

NR

4

0.0

3-7

6

4 0

.000

5-1

9 P

ossi

ble

Inge

stio

n

NR

N

R

NR

N

R

103

0

.6-4

N

R

NR

3

0.1

-39

260

0

.08

-41

Inh

ala

tion

1 N

R

1 N

R

6 0

.03

-0.5

N

R

NR

N

R

NR

3

0.0

002

-85

Der

ma

l Con

tact

2

12

3-6

8 1

94

12

-44

800

0

.000

5-9

3 1

2 0

.000

1-0

.2

34

0.0

1-3

9 7

07

0.0

002

-96

Deo

dor

an

t (U

nder

arm

) N

R

NR

N

R

NR

N

R

0.0

1-0

.5

NR

N

R

NR

N

R

1 0

.000

3-4

H

air

- N

on-C

olor

ing

NR

N

R

NR

N

R

97

0.0

002

-95

NR

N

R

1 0

.1

179

0

.000

007

-92

Ha

ir -

Col

orin

g N

R

NR

N

R

NR

5

NR

N

R

NR

N

R

NR

8

5 0

.03

-35

Na

il N

R

NR

N

R

NR

6

0.0

2-9

5 N

R

NR

N

R

0.0

01-2

5 8

0.0

5-3

0 M

ucou

s M

emb

ran

e 1

89

3-6

8 1

73

16

-44

70

0.0

1-5

2 N

R

NR

N

R

0.0

5-6

5

2 0

.000

3-4

B

ath

Pro

duct

s 1

NR

3

NR

1

9 0

.1-7

8 N

R

NR

N

R

5-4

2 1

1 0

.005

-75

Bab

y P

rod

uct

s 3

NR

4

NR

2

1 2

NR

N

R

NR

N

R

18

0.2

H

el. A

nnuu

s (S

unflo

wer

) S

eed

Oil

Uns

apon

ifiab

les

Hyd

roge

nate

d S

unflo

wer

S

eed

Oil

Ole

a E

urop

ea (

Oliv

e) F

ruit

Oil

Hyd

roge

nate

d O

live

Oil

Hyd

roge

nate

d O

live

Oil

Uns

apon

ifiab

les

Ole

a E

urop

aea

(Oliv

e) O

il U

nsap

onifi

able

s

Tot

als

10

0.00

5-2

NR

6-

35

915

0.00

05-1

00

50

0.00

05-1

2 2

0.05

-5

77

0.00

01-3

Dur

atio

n of

Use

Le

ave

-On

10

0.0

05-2

N

R

6-3

5 6

17

0.0

01-1

00

36

0.1

-12

2 0

.05

-5

68

0.0

001

-3

Rin

se-O

ff

NR

0

.002

N

R

15

-35

298

0

.000

5-9

4 1

4 0

.000

5-0

.1

NR

N

R

9 0

.04

-0.3

Exp

osur

e T

ype

Eye

Are

a

2 0

.02

NR

7

26

0.0

04-1

7 1

3 0

.1-3

N

R

0.3

-2

12

0.0

2-0

.4

Pos

sib

le In

gest

ion

N

R

NR

N

R

6 2

6 0

.7-2

6 7

0.1

-12

NR

N

R

1 0

.08

Inh

ala

tion

NR

N

R

NR

N

R

6 0

.2-5

N

R

NR

N

R

NR

N

R

3

Der

ma

l Con

tact

1

0 0

.005

-2

NR

6

-35

711

0

.000

5-1

00

34

0.0

005

-12

2 0

.05

-5

67

0.0

001

-3

Deo

dor

an

t (U

nder

arm

) N

R

NR

N

R

NR

3

0.0

2-0

.1

NR

N

R

NR

N

R

NR

N

R

Ha

ir -

Non

-Col

orin

g N

R

NR

N

R

NR

1

90

0.0

06-9

4 1

1 0

.01

-0.1

N

R

NR

6

0.0

2-0

.3

Ha

ir -

Col

orin

g N

R

NR

N

R

15

-35

NR

0

.2-0

.5

NR

N

R

NR

N

R

NR

N

R

Na

il N

R

NR

N

R

NR

5

1-4

0 N

R

NR

N

R

NR

N

R

NR

M

ucou

s M

emb

ran

e N

R

0.0

02

NR

N

R

121

0

.000

5-3

1

0.0

005

NR

N

R

4 N

R

Ba

th P

rodu

cts

NR

N

R

NR

N

R

14

0.9

-17

NR

N

R

NR

N

R

NR

N

R

Bab

y P

rod

uct

s N

R

NR

N

R

NR

9

0.2

N

R

0.4

N

R

NR

N

R

0.0

4


32

Tab

le 5

a. F

requ

ency

of u

se a

ccor

ding

to d

urat

ion

and

expo

sure

. (co

ntin

ued)

NR

= N

ot r

epor

ted

to

VC

RP

or

Cou

ncil.

NS

= N

ot y

et s

urv

eye

d.

N

o. o

f U

ses

(201

0)

Con

c. o

f U

se

(201

0) (%

) N

o. o

f U

ses

(201

0)

Con

c. o

f U

se

(201

0) (%

) N

o. o

f U

ses

(201

0)

Con

c. o

f U

se

(201

0) (%

) N

o. o

f U

ses

(201

0)

Con

c. o

f U

se

(201

0) (%

) N

o. o

f U

ses

(201

0)

Con

c. o

f U

se

(201

0) (%

) N

o. o

f U

ses

(201

0)

Con

c. o

f U

se

(201

0) (%

)

Pot

assi

um O

livat

e S

odiu

m O

livat

e A

ctin

idia

Chi

nens

is (

Kiw

i) S

eed

Oil

Ada

nson

ia D

igita

ta O

il [B

aoba

b]

Arg

ania

Spi

nosa

Ker

nel O

il [A

rgan

] A

stro

cary

um M

urum

uru

See

d B

utte

r [M

urum

ura]

Tot

als

3 N

R

16

4-18

7

0.1

6 0.

01

100

0.00

1-10

19

2 0.

001-

7

Dur

atio

n of

Use

Le

ave

-On

NR

N

R

5 N

R

5 N

R

4 0

.01

87

0.0

01-1

0 1

71

0.0

01-7

Rin

se O

ff

3 N

R

11

4-1

8 2

0.1

2

NR

1

3 0

.001

-2

21

0.0

01-0

.2

Exp

osur

e T

ype

Eye

Are

a

NR

N

R

NR

N

R

NR

N

R

NR

N

R

11

0.1

-1

21

0.0

6-0

.5

Pos

sib

le In

gest

ion

N

R

NR

N

R

NR

1

NR

N

R

0.0

1 9

0.1

-1

22

1-7

In

ha

latio

n N

R

NR

N

R

NR

1

NR

N

R

NR

N

R

0.0

1 N

R

NR

D

erm

al C

onta

ct

3 N

R

16

4-1

8 5

NR

5

0.0

1 8

8 0

.001

-10

178

0

.001

-7

Deo

dor

an

t (U

nder

arm

) N

R

NR

N

R

NR

N

R

NR

N

R

NR

N

R

0.0

01

NR

N

R

Ha

ir -

Non

-Col

orin

g N

R

NR

N

R

NR

2

0.1

1

NR

8

0.0

1-1

1

1 0

.001

-0.2

H

air

- C

olor

ing

NR

N

R

NR

N

R

NR

N

R

NR

N

R

NR

0

.07

-0.1

3

NR

N

ail

NR

N

R

NR

N

R

NR

N

R

NR

N

R

2 0

.001

-0..1

N

R

NR

M

ucou

s M

emb

ran

e 1

NR

9

4-1

8 N

R

NR

N

R

NR

2

0.0

01-2

3

NR

B

ath

Pro

duct

s N

R

NR

N

R

NR

N

R

NR

N

R

NR

1

0.0

5 N

R

NR

B

aby

Pro

du

cts

NR

N

R

1 N

R

NR

N

R

1 N

R

NR

N

R

NR

N

R

S

odiu

m A

stro

cary

um

Mur

umur

uate

A

vena

Sat

iva

(Oat

) K

erne

l O

il B

orag

o O

ffici

nalis

See

d O

il [B

orag

e]

Bra

ssic

a O

lera

cea

Italic

a (B

rocc

oli)

See

d O

il C

amel

ina

Sat

iva

See

d O

il [F

alse

Fla

x]

Cam

ellia

Jap

onic

a S

eed

Oil

Tot

als

NR

0.

002-

0.00

5 43

0.

01-3

18

0 0.

001-

1 N

R

0.00

1-3

76

0.00

2-1

NR

0.

01-0

.2

Dur

atio

n of

Use

Le

ave

-On

NR

0

.002

3

7 0

.1-3

1

60

0.0

01-1

N

R

3 6

1 0

.002

-1

NR

0

.01

-0.2

Rin

se-O

ff

NR

0

.002

-0.0

05

6 0

.001

-0.1

2

0 0

.001

-0.0

1 N

R

0.0

01-0

.5

15

1 N

R

0.1

Exp

osur

e T

ype

Eye

Are

a

NR

N

R

NR

0

.2

7 0

.001

-0.5

N

R

NR

N

R

0.0

5 N

R

0.0

1 P

ossi

ble

Inge

stio

n

NR

N

R

NR

2

NR

0

.01

NR

N

R

34

0.0

5-0

.5

NR

0

.1

Inh

ala

tion

NR

N

R

NR

N

R

3 0

.1

NR

N

R

NR

N

R

NR

N

R

Der

ma

l Con

tact

N

R

0.0

02-0

.005

4

1 0

.001

-3

168

0

.001

-1

NR

N

R

47

0.0

02-1

N

R

0.0

1-0

.2

Deo

dor

an

t (U

nder

arm

) N

R

NR

N

R

NR

N

R

NR

N

R

NR

N

R

NR

N

R

0.0

1

Ha

ir -

Non

-Col

orin

g N

R

NR

2

0.1

1

0 N

R

NR

N

R

29

1 N

R

0.1

H

air

- C

olor

ing

NR

N

R

NR

N

R

NR

N

R

NR

0

.001

-3

NR

N

R

NR

N

R

Na

il N

R

NR

N

R

NR

N

R

NR

N

R

NR

N

R

NR

N

R

NR

M

ucou

s M

emb

ran

e N

R

0.0

02

2 0

.01

-0.1

4

0.0

01-0

.01

NR

N

R

NR

N

R

NR

0

.1

Ba

th P

rodu

cts

NR

N

R

1 N

R

1 N

R

NR

N

R

NR

N

R

NR

N

R

Bab

y P

rod

uct

s N

R

NR

6

0.1

3

NR

N

R

NR

N

R

NR

N

R

NR


33

Tab

le 5

a. F

requ

ency

of u

se a

ccor

ding

to d

urat

ion

and

expo

sure

. (co

ntin

ued)

NR

= N

ot r

epor

ted

to

VC

RP

or

Cou

ncil.

NS

= N

ot y

et s

urv

eye

d.

N

o. o

f U

ses

(201

0)

Con

c. o

f U

se

(201

0) (%

) N

o. o

f U

ses

(201

0)

Con

c. o

f U

se

(201

0) (%

) N

o. o

f U

ses

(201

0)

Con

c. o

f U

se

(201

0) (%

) N

o. o

f U

ses

(201

0)

Con

c. o

f U

se

(201

0) (%

) N

o. o

f U

ses

(201

0)

Con

c. o

f U

se

(201

0) (%

) N

o. o

f U

ses

(201

0)

Con

c. o

f U

se

(201

0) (%

)

Cam

ellia

Ole

ifera

See

d O

il [T

ea S

eed]

H

ydro

gena

ted

Cam

ellia

O

leife

ra S

eed

Oil

Cam

ellia

Sin

ensi

s S

eed

Oil

Car

ica

Pap

aya

See

d O

il C

aryo

car

Bra

sile

nse

Fru

it O

il (P

equi

) C

heno

podi

um Q

uino

a S

eed

Oil

[Qui

noa]

Tot

als

25

0.00

3-3

1 N

R

12

0.1

NR

0.

1 31

0.

0005

-0.2

1

0.3

Dur

atio

n of

Use

Le

ave

-On

23

0.0

03-3

1

NR

8

0.1

N

R

0.1

2

9 0

.000

5-2

1

NR

Rin

se O

ff

2 0

.01

-0.1

N

R

NR

4

0.1

N

R

NR

2

NR

N

R

0.3

Exp

osur

e T

ype

Eye

Are

a

NR

2

NR

N

R

NR

N

R

NR

N

R

12

NR

N

R

NR

P

ossi

ble

Inge

stio

n

3 3

NR

N

R

1 0

.1

NR

N

R

12

0.2

N

R

NR

In

ha

latio

n N

R

NR

N

R

NR

N

R

NR

N

R

NR

N

R

NR

N

R

NR

D

erm

al C

onta

ct

23

0.0

03-3

1

NR

1

0 0

.1

NR

0

.1

30

0.0

005

-0.2

N

R

NR

D

eod

ora

nt

(Und

era

rm)

NR

N

R

NR

N

R

NR

0

.1

NR

N

R

NR

N

R

NR

N

R

Ha

ir -

Non

-Col

orin

g 2

2 N

R

NR

2

0.1

N

R

NR

1

NR

1

NR

H

air

- C

olor

ing

NR

N

R

NR

N

R

NR

N

R

NR

N

R

NR

N

R

NR

0

.3

Na

il N

R

NR

N

R

NR

N

R

NR

N

R

NR

N

R

NR

N

R

NR

M

ucou

s M

emb

ran

e N

R

0.0

1-0

.1

NR

N

R

2 0

.1

NR

N

R

NR

N

R

NR

N

R

Ba

th P

rodu

cts

NR

0

.05

NR

N

R

NR

N

R

NR

N

R

NR

N

R

NR

N

R

Bab

y P

rod

uct

s N

R

NR

N

R

NR

N

R

NR

N

R

NR

N

R

NR

N

R

NR

C

itrul

lus

Lana

tus

(Wat

erm

elon

) S

eed

Oil

Citr

us V

ulga

ris

(Wat

erm

elon

) S

eed

Oil

Citr

us G

rand

is (

Gra

pefr

uit)

S

eed

Oil

Citr

us P

arad

isi (

Gra

pefr

uit)

S

eed

Oil

Citr

us M

edic

a Li

mon

um

(Lem

on)

See

d O

il C

ucum

is S

ativ

us (

Cuc

umbe

r)

See

d O

il

Tot

als

1 2

1 N

R

NR

0.

1 6

NR

5

NR

6

NR

D

urat

ion

of U

se

Le

ave

-On

1 2

1 N

R

NR

0

.1

5 N

R

3 N

R

5 N

R

Rin

se-O

ff

NR

N

R

NR

N

R

NR

0

.1

1 N

R

2 N

R

1 N

R

Exp

osur

e T

ype

Eye

Are

a

NR

N

R

NR

N

R

NR

N

R

NR

N

R

NR

N

R

1 N

R

Pos

sib

le In

gest

ion

N

R

NR

N

R

NR

N

R

0.1

N

R

NR

N

R

NR

N

R

NR

In

ha

latio

n N

R

NR

N

R

NR

N

R

NR

N

R

NR

N

R

NR

N

R

NR

D

erm

al C

onta

ct

1 2

1 N

R

NR

0

.1

6 N

R

5 N

R

5 N

R

Deo

dor

an

t (U

nder

arm

) N

R

NR

N

R

NR

N

R

NR

N

R

NR

N

R

NR

N

R

NR

H

air

- N

on-C

olor

ing

NR

N

R

NR

N

R

NR

0

.1

NR

N

R

NR

N

R

1 N

R

Ha

ir -

Col

orin

g N

R

NR

N

R

NR

N

R

NR

N

R

NR

N

R

NR

N

R

NR

N

ail

NR

N

R

NR

N

R

NR

N

R

NR

N

R

NR

N

R

NR

N

R

Muc

ous

Mem

bra

ne

NR

N

R

NR

N

R

NR

0

.1

1 N

R

1 N

R

NR

N

R

Ba

th P

rodu

cts

NR

N

R

NR

N

R

NR

N

R

NR

N

R

NR

N

R

NR

N

R

Bab

y P

rod

uct

s N

R

NR

N

R

NR

N

R

NR

N

R

NR

N

R

NR

N

R

NR


34

Tab

le 5

a. F

requ

ency

of u

se a

ccor

ding

to d

urat

ion

and

expo

sure

. (co

ntin

ued)

NR

= N

ot r

epor

ted

to

VC

RP

or

Cou

ncil.

NS

= N

ot y

et s

urv

eye

d.

N

o. o

f U

ses

(201

0)

Con

c. o

f U

se

(201

0) (%

) N

o. o

f U

ses

(201

0)

Con

c. o

f U

se

(201

0) (%

) N

o. o

f U

ses

(201

0)

Con

c. o

f U

se

(201

0) (%

) N

o. o

f U

ses

(201

0)

Con

c. o

f U

se

(201

0) (%

) N

o. o

f U

ses

(201

0)

Con

c. o

f U

se

(201

0) (%

) N

o. o

f U

ses

(201

0)

Con

c. o

f U

se

(201

0) (%

)

Cuc

urbi

ta P

epo

(Pum

pkin

) S

eed

Oil

Eut

erpe

Ole

race

a F

ruit

Oil

[Aca

i] Ir

ving

ia G

abon

ensi

s K

erne

l B

utte

r [D

ika]

Li

mna

nthe

s A

lba

(Mea

dow

foam

) S

eed

Oil

Linu

m U

sita

tissi

mum

(L

inse

ed)

See

d O

il Li

nsee

d A

cid

Tot

als

18

0.00

3-0.

1 29

0.

0000

1-0.

5 10

9 0.

003-

0.4

316

0.00

2-74

10

2 0.

001-

10

3 N

R

Dur

atio

n of

Use

Le

ave

-On

17

0.0

03-0

.1

19

0.0

000

1-0

.5

109

0

.003

-0.4

2

25

0.0

02-7

4 5

2 0

.002

-10

3 N

R

Rin

se O

ff

1 N

R

10

0.0

5 N

R

NR

9

1 0

.01

-2

50

0.0

01-0

.4

NR

N

R

Exp

osur

e T

ype

Eye

Are

a

1 0

.003

2

0.5

2

NR

3

0 0

.1-2

0 3

0.0

1 N

R

NR

P

ossi

ble

Inge

stio

n

NR

N

R

1 0

.002

6

4 0

.003

-0.3

6

7 0

.6-2

6 N

R

0.0

1 N

R

NR

In

ha

latio

n 1

NR

1

NR

N

R

NR

1

0.1

-3

3 N

R

NR

N

R

Der

ma

l Con

tact

1

8 0

.003

-0.1

1

4 0

.000

01

-0.5

1

08

0.0

03-0

.4

211

0

.002

-74

58

0.0

03-4

3

NR

D

eod

ora

nt

(Und

era

rm)

NR

N

R

NR

N

R

NR

N

R

NR

N

R

NR

0

.05

-0.1

N

R

NR

H

air

- N

on-C

olor

ing

1 N

R

15

NR

1

NR

4

7 0

.1-1

4

2 0

.001

-0.1

N

R

NR

H

air

- C

olor

ing

NR

N

R

NR

N

R

NR

N

R

46

0.2

-2

NR

N

R

NR

N

R

Na

il N

R

NR

N

R

NR

N

R

NR

N

R

0.5

2

0.0

02-0

.05

NR

N

R

Muc

ous

Mem

bra

ne

NR

N

R

3 N

R

NR

N

R

4 0

.001

-0.6

5

0.0

03-0

.4

NR

N

R

Ba

th P

rodu

cts

NR

N

R

NR

N

R

NR

N

R

2 0

.5-0

.9

1 0

.02

-0.2

N

R

NR

B

aby

Pro

du

cts

NR

N

R

NR

N

R

NR

N

R

1 N

R

2 N

R

1 N

R

M

angi

fera

Indi

ca (

Man

go)

See

d O

il M

angi

fera

Indi

ca (

Man

go)

See

d B

utte

r S

odiu

m M

ango

seed

ate

Mor

inga

Ole

ifera

See

d O

il [B

en]

Mor

inga

Pte

rygo

sper

ma

See

d O

il O

enot

hera

Bie

nnis

(E

veni

ng

Prim

rose

) O

il

Tot

als

72

0.00

3-6

175

0.00

05-3

1

NR

N

R

0.00

1 15

0.

003-

3 15

0 0.

0000

2-58

D

urat

ion

of U

se

Le

ave

-On

64

0.0

03-6

1

34

0.0

1-5

N

R

NR

N

R

0.0

01

13

0.0

04-3

1

13

0.0

000

2-5

8 R

inse

-Off

8 0

.05

-0.2

4

1 0

.000

5-0

.5

1 N

R

NR

N

R

2 0

.003

3

7 0

.002

-0.2

E

xpos

ure

Typ

e

Eye

Are

a

13

5 6

0.0

2 N

R

NR

N

R

NR

4

3 4

0.0

000

2-0

.5

Pos

sib

le In

gest

ion

7

0.0

3-6

2

5 1

-5

NR

N

R

NR

N

R

1 N

R

14

0.1

-15

Inh

ala

tion

1 N

R

2 0

.02

NR

N

R

NR

N

R

NR

N

R

2 N

R

Der

ma

l Con

tact

6

0 0

.003

-6

147

0

.000

5-5

1

NR

N

R

0.0

01

11

0.0

03-3

1

09

0.0

000

2-5

8 D

eod

ora

nt

(Und

era

rm)

NR

N

R

NR

N

R

NR

N

R

NR

N

R

NR

N

R

NR

0

.2

Ha

ir -

Non

-Col

orin

g 1

2 0

.05

-0.2

1

2 0

.02

-0.5

N

R

NR

N

R

NR

1

0.0

2 3

7 0

.05

-0.1

H

air

- C

olor

ing

NR

0

.05

16

NR

N

R

NR

N

R

NR

N

R

NR

N

R

NR

N

ail

NR

N

R

NR

0

.5

NR

N

R

NR

N

R

NR

N

R

4 0

.001

-3

Muc

ous

Mem

bra

ne

2 0

.1

10

0.0

005

-0.5

1

NR

N

R

NR

N

R

0.0

03

4 0

.1-0

.2

Ba

th P

rodu

cts

NR

N

R

1 N

R

NR

N

R

NR

N

R

NR

N

R

2 0

.2

Bab

y P

rod

uct

s N

R

NR

3

NR

N

R

NR

N

R

NR

N

R

NR

3

NR


35

Tab

le 5

a. F

requ

ency

of u

se a

ccor

ding

to d

urat

ion

and

expo

sure

. (co

ntin

ued)

NR

= N

ot r

epor

ted

to

VC

RP

or

Cou

ncil.

NS

= N

ot y

et s

urv

eye

d.

N

o. o

f U

ses

(201

0)

Con

c. o

f U

se

(201

0) (%

) N

o. o

f U

ses

(201

0)

Con

c. o

f U

se

(201

0) (%

) N

o. o

f U

ses

(201

0)

Con

c. o

f U

se

(201

0) (%

) N

o. o

f U

ses

(201

0)

Con

c. o

f U

se

(201

0) (%

) N

o. o

f U

ses

(201

0)

Con

c. o

f U

se

(201

0) (%

) N

o. o

f U

ses

(201

0)

Con

c. o

f U

se

(201

0) (%

)

Hyd

roge

nate

d E

veni

ng

Prim

rose

Oil

Org

ibny

a C

ohum

e S

eed

Oil

Orb

igny

a O

leife

ra S

eed

Oil

[Bab

assu

] S

odiu

m B

abas

suat

e P

erill

a O

cym

oide

s S

eed

Oil

[Per

illa]

H

ydro

gena

ted

Avo

cado

Oil

Tot

als

14

NR

1

NR

16

1 0.

0009

-27

NR

8

7 N

R

11

0.5

Dur

atio

n of

Use

Le

ave

-On

14

NR

N

R

NR

1

18

0.0

009

-4

NR

N

R

5 N

R

9 N

R

Rin

se O

ff

NR

N

R

1 N

R

43

0.0

1-2

7 N

R

8 2

NR

2

0.5

Exp

osur

e T

ype

Eye

Are

a

1 N

R

NR

N

R

7 0

.5-0

.6

NR

N

R

2 N

R

NR

N

R

Pos

sib

le In

gest

ion

N

R

NR

N

R

NR

5

7 0

.001

-2

NR

N

R

NR

N

R

2 N

R

Inh

ala

tion

NR

N

R

NR

N

R

5 0

.02

-2

NR

N

R

NR

N

R

NR

N

R

Der

ma

l Con

tact

1

4 N

R

NR

N

R

110

0

.000

9-2

7 N

R

8 5

NR

8

NR

D

eod

ora

nt

(Und

era

rm)

NR

N

R

NR

N

R

NR

N

R

NR

N

R

NR

N

R

NR

N

R

Ha

ir -

Non

-Col

orin

g N

R

NR

1

NR

4

3 0

.02

-2

NR

N

R

2 N

R

3 0

.5

Ha

ir -

Col

orin

g N

R

NR

N

R

NR

8

NR

N

R

NR

N

R

NR

N

R

NR

N

ail

NR

N

R

NR

N

R

NR

N

R

NR

N

R

NR

N

R

NR

N

R

Muc

ous

Mem

bra

ne

NR

N

R

NR

N

R

5 2

7 N

R

8 N

R

NR

N

R

NR

B

ath

Pro

duct

s N

R

NR

N

R

NR

2

0.0

1-0

.1

NR

N

R

NR

N

R

NR

N

R

Bab

y P

rod

uct

s N

R

NR

N

R

NR

N

R

NR

N

R

NR

N

R

NR

N

R

NR

P

erse

a G

ratis

sim

a (A

voca

do)

But

ter

Per

sea

Gra

tissi

ma

(Avo

cado

) O

il U

nsap

on.

Sod

ium

Avo

cado

ate

Plu

kene

tia V

olub

ilis

See

d O

il [S

acha

Inch

i] P

runu

s A

rmen

iaca

(A

pric

ot)

Ker

nel O

il H

ydro

gena

ted

Apr

icot

K

erne

l Oil

Tot

als

15

NR

63

0.

2-6

1 N

R

13

NS

58

8 0.

0000

1-89

2

NR

D

urat

ion

of U

se

Le

ave

-On

15

NR

5

7 0

.5-6

N

R

NR

1

2 N

S

449

0

.000

1-4

0 2

NR

R

inse

-Off

NR

N

R

6 0

.2

1 N

R

1 N

S

139

0

.000

01

-89

NR

N

R

Exp

osur

e T

ype

Eye

Are

a

NR

N

R

9 0

.5

NR

N

R

1 N

S

25

0.0

02-1

8 N

R

NR

P

ossi

ble

Inge

stio

n

11

NR

2

3 N

R

NR

3

NS

3

8 0

.001

-5

NR

N

R

Inh

ala

tion

NR

N

R

4 N

R

NR

N

R

NR

N

S

5 0

.000

9-1

N

R

NR

D

erm

al C

onta

ct

15

NR

5

6 0

.2-3

1

NR

1

3 N

S

486

0

.000

01

-18

2 N

R

Deo

dor

an

t (U

nder

arm

) N

R

NR

N

R

NR

N

R

NR

N

R

NS

1

0.0

03-0

.1

NR

N

R

Ha

ir -

Non

-Col

orin

g N

R

NR

2

6 N

R

NR

N

R

NS

7

8 0

.000

1-8

9 N

R

NR

H

air

- C

olor

ing

NR

N

R

NR

N

R

NR

N

R

NR

N

S

10

0.1

N

R

NR

N

ail

NR

N

R

3 N

R

NR

N

R

NR

N

S

10

0.0

02-4

0 N

R

NR

M

ucou

s M

emb

ran

e N

R

NR

N

R

NR

1

NR

N

R

NS

2

4 0

.01

-9

NR

N

R

Ba

th P

rodu

cts

NR

N

R

4 N

R

NR

N

R

NR

N

S

8 4

NR

N

R

Bab

y P

rod

uct

s N

R

NR

1

NR

N

R

NR

N

R

NS

7

NR

N

R

NR


36

Tab

le 5

a. F

requ

ency

of u

se a

ccor

ding

to d

urat

ion

and

expo

sure

. (co

ntin

ued)

NR

= N

ot r

epor

ted

to

VC

RP

or

Cou

ncil.

NS

= N

ot y

et s

urv

eye

d.

N

o. o

f U

ses

(201

0)

Con

c. o

f U

se

(201

0) (%

) N

o. o

f U

ses

(201

0)

Con

c. o

f U

se

(201

0) (%

) N

o. o

f U

ses

(201

0)

Con

c. o

f U

se

(201

0) (%

) N

o. o

f U

ses

(201

0)

Con

c. o

f U

se

(201

0) (%

) N

o. o

f U

ses

(201

0)

Con

c. o

f U

se

(201

0) (%

) N

o. o

f U

ses

(201

0)

Con

c. o

f U

se

(201

0) (%

)

Pru

nus

Avi

um (

Sw

eet

Che

rry)

See

d O

il P

runu

s D

omes

tica

See

d O

il [P

rune

/Plu

m]

Pru

nus

Per

sica

(P

each

) K

erne

l Oil

Pyr

us M

alus

(A

pple

) S

eed

Oil

Rib

es N

igru

m (

Bla

ck

Cur

rant

) S

eed

Oil

Rub

us Id

aeus

(R

aspb

erry

) S

eed

Oil

Tot

als

2 0.

01-0

.02

NR

0.

04

22

0.00

3-22

8

NR

53

0.

0000

01-0

.3

10

0.1-

5

Dur

atio

n of

Use

Le

ave

-On

NR

N

R

NR

N

R

16

0.0

5-2

2 8

NR

4

5 0

.000

001

-0.3

8

0.1

-5

Rin

se O

ff

2 0

.01

-+0

.02

NR

0

.04

6 0

.003

-6

NR

N

R

8 0

.05

2 N

R

Exp

osur

e T

ype

Eye

Are

a

NR

N

R

NR

N

R

NR

N

R

NR

N

R

2 0

.08

NR

N

R

Pos

sib

le In

gest

ion

N

R

NR

N

R

NR

N

R

0.0

4-2

2 1

NR

7

0.0

3-0

.1

1 N

R

Inh

ala

tion

NR

N

R

NR

N

R

NR

2

NR

N

R

NR

N

R

NR

N

R

Der

ma

l Con

tact

2

0.0

1-0

.02

NR

0

.04

18

0.0

03-2

2 8

NR

4

3 0

.000

001

-0.3

8

0.1

-5

Deo

dor

an

t (U

nder

arm

) N

R

NR

N

R

NR

N

R

NR

N

R

NR

N

R

NR

N

R

NR

H

air

- N

on-C

olor

ing

NR

N

R

NR

N

R

4 N

R

NR

N

R

5 N

R

NR

N

R

Ha

ir -

Col

orin

g N

R

NR

N

R

NR

N

R

0.1

N

R

NR

N

R

NR

N

R

NR

N

ail

NR

N

R

NR

N

R

NR

N

R

NR

N

R

5 0

.2

NR

N

R

Muc

ous

Mem

bra

ne

2 0

.01

-0.0

2 N

R

NR

1

NR

N

R

NR

2

NR

2

NR

B

ath

Pro

duct

s N

R

NR

N

R

NR

1

0.1

-1

NR

N

R

NR

N

R

1 N

R

Bab

y P

rod

uct

s N

R

NR

N

R

NR

N

R

NR

N

R

NR

N

R

NR

N

R

NR

S

cler

ocar

ya B

irrea

See

d O

il [M

arul

a]

Sily

bum

Mar

ianu

m S

eed

Oil

[Thi

stle

] S

olan

um L

ycop

ersi

cum

(T

omat

o) S

eed

Oil

Sol

anum

Lyc

oper

sicu

m

(Tom

ato)

Fru

it O

il T

heob

rom

a C

acao

(C

ocoa

) S

eed

But

ter

The

obro

ma

Gra

ndifl

orum

S

eed

But

ter

[Cap

uacu

]

Tot

als

29

1 N

R

0.5

1 N

R

NR

0.

01-1

44

2 0.

0000

02-3

7 15

3 0.

0000

5-7

Dur

atio

n of

Use

Le

ave

-On

23

1 N

R

0.5

1

NR

N

R

0.0

01-1

3

67

0.0

000

02-3

7 1

19

0.0

000

5-7

R

inse

-Off

6 1

NR

N

R

NR

N

R

NR

N

R

75

0.0

001

-2

34

0.0

01-1

E

xpos

ure

Typ

e

Eye

Are

a

NR

N

R

NR

N

R

NR

N

R

NR

0

.01

11

0.0

002

-9

21

0.1

-2

Pos

sib

le In

gest

ion

6

NR

N

R

NR

N

R

NR

N

R

0.0

01

33

37

49

7 In

ha

latio

n 2

NR

N

R

NR

N

R

NR

N

R

NR

2

0.4

N

R

NR

D

erm

al C

onta

ct

23

1 N

R

0.5

1

NR

N

R

0.0

01-1

4

17

0.0

000

02-3

7 1

41

0.0

000

5-7

D

eod

ora

nt

(Und

era

rm)

NR

N

R

NR

N

R

NR

N

R

NR

N

R

NR

0

.001

-1

NR

0

.1

Ha

ir -

Non

-Col

orin

g 6

1 N

R

NR

N

R

NR

N

R

NR

2

4 0

.01

-2

9 0

.001

-1

Ha

ir -

Col

orin

g N

R

NR

N

R

NR

N

R

NR

N

R

NR

N

R

0.1

3

NR

N

ail

NR

N

R

NR

N

R

NR

N

R

NR

N

R

NR

0

.1-1

N

R

NR

M

ucou

s M

emb

ran

e 2

NR

N

R

NR

N

R

NR

N

R

NR

3

5 0

.02

-2

19

0.0

5-0

.1

Ba

th P

rodu

cts

NR

N

R

NR

N

R

NR

N

R

NR

N

R

4 0

.1-1

4

NR

B

aby

Pro

du

cts

NR

N

R

NR

N

R

NR

N

R

NR

N

R

8 0

.01

NR

N

R


37

Tab

le 5

a. F

requ

ency

of u

se a

ccor

ding

to d

urat

ion

and

expo

sure

. (co

ntin

ued)

NR

= N

ot r

epor

ted

to

VC

RP

or

Cou

ncil.

NS

= N

ot y

et s

urv

eye

d.

N

o. o

f U

ses

(201

0)

Con

c. o

f U

se

(201

0) (%

) N

o. o

f U

ses

(201

0)

Con

c. o

f U

se

(201

0) (%

) N

o. o

f U

ses

(201

0)

Con

c. o

f U

se

(201

0) (%

) N

o. o

f U

ses

(201

0)

Con

c. o

f U

se

(201

0) (%

) N

o. o

f U

ses

(201

0)

Con

c. o

f U

se

(201

0) (%

) N

o. o

f U

ses

(201

0)

Con

c. o

f U

se

(201

0) (%

)

Trit

icum

Vul

gare

(W

heat

) G

erm

Oil

Uns

apon

ifiab

les

Whe

at G

erm

Aci

d V

acci

nium

Mac

roca

rpon

(C

ranb

erry

) S

eed

Oil

Vac

cini

um O

xyco

ccos

(C

ranb

erry

) S

eed

Oil

Viti

s V

inife

ra (

Gra

pe)

See

d O

il S

odiu

m G

rape

seed

ate

Tot

als

17

0.2

16

NR

21

0.

002-

2 4

NS

46

5 0.

001-

43

4 N

R

Dur

atio

n of

Use

Le

ave

-On

17

0.2

3

NR

1

8 0

.002

-2

3 N

S

368

0

.001

-41

4 N

R

Rin

se O

ff

NR

N

R

13

NR

3

0.0

03-0

.1

1 N

S

97

0.0

01-4

3 N

R

NR

E

xpos

ure

Typ

e

Eye

Are

a

1 N

R

NR

N

R

2 N

R

NR

N

S

14

0.0

1-5

N

R

NR

P

ossi

ble

Inge

stio

n

NR

N

R

NR

N

R

NR

0

.3

NR

N

S

34

0.0

3-7

N

R

NR

In

ha

latio

n N

R

NR

N

R

NR

N

R

NR

N

R

NS

6

0.0

01-7

N

R

NR

D

erm

al C

onta

ct

17

0.2

N

R

NR

1

7 0

.002

-2

4 N

S

401

0

.001

-41

NR

N

R

Deo

dor

an

t (U

nder

arm

) N

R

NR

N

R

NR

N

R

NR

N

R

NS

N

R

0.0

01-0

.2

NR

N

R

Ha

ir -

Non

-Col

orin

g N

R

NR

1

6 N

R

4 0

.01

-0.1

N

R

NS

4

6 0

.01

-0.3

4

NR

H

air

- C

olor

ing

NR

N

R

NR

N

R

NR

N

R

NR

N

S

10

43

NR

N

R

Na

il N

R

NR

N

R

NR

N

R

NR

N

R

NS

8

0.0

01-3

5 N

R

NR

M

ucou

s M

emb

ran

e N

R

NR

N

R

NR

1

0.0

03-0

.1

NR

N

S

21

0.0

01-7

N

R

NR

B

ath

Pro

duct

s N

R

NR

N

R

NR

N

R

NR

N

R

NS

8

0.0

1-2

N

R

NR

B

aby

Pro

du

cts

NR

N

R

NR

N

R

NR

N

R

NR

N

S

5 N

R

NR

N

R

H

ydro

gena

ted

Gra

pese

ed O

il B

assi

a La

tifol

ia S

eed

But

ter

Cam

ellia

Kis

si S

eed

Oil

Cra

mbe

Aby

ssin

ica

See

d O

il G

arci

nia

Indi

ca S

eed

But

ter

Hip

poph

ae R

ham

noid

es

Fru

it O

il

Tot

als

7 0.

3-0.

5 22

N

S

47

NS

26

N

S

30

NS

7

NS

D

urat

ion

of U

se

Le

ave

-On

4 0

.3-0

.5

17

NS

3

4 N

S

15

NS

2

7 N

S

7 N

S

Rin

se O

ff

3 0

.5

5 N

S

13

NS

1

1 N

S

3 N

S

NR

N

S

Exp

osur

e T

ype

Eye

Are

a

NR

N

R

4 N

S

4 N

S

1 N

S

1 N

S

1 N

S

Pos

sib

le In

gest

ion

1

0.5

N

R

NS

1

NS

1

NS

3

NS

N

R

NS

In

ha

latio

n N

R

NR

N

R

NS

N

R

NS

N

R

NS

N

R

NS

N

R

NS

D

erm

al C

onta

ct

5 0

.5

22

NS

3

6 N

S

8 N

S

30

NS

6

NS

D

eod

ora

nt

(Und

era

rm)

NR

N

R

NR

N

S

NR

N

S

NR

N

S

NR

N

S

NR

N

S

Ha

ir -

Non

-Col

orin

g 1

NR

N

R

NS

1

1 N

S

14

NS

N

R

NS

N

R

NS

H

air

- C

olor

ing

NR

N

R

NR

N

S

NR

N

S

4 N

S

NR

N

S

NR

N

S

Na

il 1

0.3

N

R

NS

N

R

NS

N

R

NS

N

R

NS

1

NS

M

ucou

s M

emb

ran

e 1

NR

5

NS

1

NS

N

R

NS

1

NS

N

R

NS

B

ath

Pro

duct

s N

R

NR

N

R

NS

1

NS

N

R

NS

N

R

NS

N

R

NS

B

aby

Pro

du

cts

NR

N

R

NR

N

S

NR

N

S

NR

N

S

NR

N

S

NR

N

S


38

Tab

le 5

a. F

requ

ency

of u

se a

ccor

ding

to d

urat

ion

and

expo

sure

. (co

ntin

ued)

NR

= N

ot r

epor

ted

to

VC

RP

or

Cou

ncil.

NS

= N

ot y

et s

urv

eye

d.

N

o. o

f U

ses

(201

0)

Con

c. o

f U

se

(201

0) (%

) N

o. o

f U

ses

(201

0)

Con

c. o

f U

se

(201

0) (%

) N

o. o

f U

ses

(201

0)

Con

c. o

f U

se

(201

0) (%

) N

o. o

f U

ses

(201

0)

Con

c. o

f U

se

(201

0) (%

) N

o. o

f U

ses

(201

0)

Con

c. o

f U

se

(201

0) (%

) N

o. o

f U

ses

(201

0)

Con

c. o

f U

se

(201

0) (%

)

Hip

poph

ae R

ham

noid

es O

il Lu

ffa C

ylin

dric

a S

eed

Oil

Lupi

nus

Alb

us S

eed

Oil

Lyci

um B

arba

rum

See

d O

il O

rbig

nya

Spe

cios

a K

erne

l O

il P

assi

flora

Edu

lis S

eed

Oil

Tot

als

15

NS

21

N

S

1 N

S

2 N

S

8 N

S

62

NS

D

urat

ion

of U

se

Le

ave

-On

10

NS

2

1 N

S

1 N

S

2 N

S

1 N

S

53

NS

R

inse

Off

5 N

S

NR

N

S

NR

N

S

NR

N

S

7 N

S

9 N

S

Exp

osur

e T

ype

Eye

Are

a

NR

N

S

1 N

S

NR

N

S

1 N

S

NR

N

S

3 N

S

Pos

sib

le In

gest

ion

N

R

NS

9

NS

N

R

NS

1

NS

N

R

NS

1

4 N

S

Inh

ala

tion

NR

N

S

NR

N

S

NR

N

S

NR

N

S

NR

N

S

3 N

S

Der

ma

l Con

tact

1

NS

2

1 N

S

1 N

S

2 N

S

NR

N

S

49

NS

D

eod

ora

nt

(Und

era

rm)

NR

N

S

NR

N

S

NR

N

S

NR

N

S

NR

N

S

NR

N

S

Ha

ir -

Non

-Col

orin

g 6

NS

N

R

NS

N

R

NS

N

R

NS

5

NS

1

0 N

S

Ha

ir -

Col

orin

g N

R

NS

N

R

NS

N

R

NS

N

R

NS

3

NS

3

NS

N

ail

8 N

S

NR

N

S

NR

N

S

NR

N

S

NR

N

S

NR

N

S

Muc

ous

Mem

bra

ne

1 N

S

NR

N

S

NR

N

S

NR

N

S

NR

N

S

1 N

S

Ba

th P

rodu

cts

NR

N

S

NR

N

S

NR

N

S

NR

N

S

NR

N

S

NR

N

S

Bab

y P

rod

uct

s N

R

NS

N

R

NS

N

R

NS

N

R

NS

N

R

NS

N

R

NS

P

unic

a G

rana

tum

See

d O

il R

osa

Can

ina

Fru

it O

il R

ubus

Cha

mem

orus

See

d O

il V

acci

nium

Myr

tillu

s S

eed

Oil

Vac

cini

um V

itis-

Idae

a S

eed

Oil

Van

illa

Pla

nifo

lia F

ruit

Oil

Tot

als

46

NS

12

1 N

S

3 N

S

33

NS

9

NS

9

NS

D

urat

ion

of U

se

Le

ave

-On

44

NS

1

06

NS

3

NS

3

2 N

S

9 N

S

8 N

S

Rin

se O

ff

2 N

S

15

NS

N

R

NS

1

NS

N

R

NS

1

NS

E

xpos

ure

Typ

e

Eye

Are

a

2 N

S

17

NS

N

R

NS

N

R

NS

N

R

NS

2

NS

P

ossi

ble

Inge

stio

n

30

NS

7

NS

N

R

NS

2

9 N

S

NR

N

S

NR

N

S

Inh

ala

tion

NR

N

S

1 N

S

NR

N

S

NR

N

S

NR

N

S

NR

N

S

Der

ma

l Con

tact

4

6 N

S

109

N

S

3 N

S

33

NS

1

NS

9

NS

D

eod

ora

nt

(Und

era

rm)

NR

N

S

NR

N

S

NR

N

S

NR

N

S

NR

N

S

NR

N

S

Ha

ir -

Non

-Col

orin

g N

R

NS

9

NS

N

R

NS

N

R

NS

N

R

NS

N

R

NS

H

air

- C

olor

ing

NR

N

S

NR

N

S

NR

N

S

NR

N

S

NR

N

S

NR

N

S

Na

il N

R

NS

1

NS

N

R

NS

N

R

NS

8

NS

N

R

NS

M

ucou

s M

emb

ran

e 2

NS

3

NS

N

R

NS

N

R

NS

N

R

NS

1

NS

B

ath

Pro

duct

s N

R

NS

1

NS

N

R

NS

N

R

NS

N

R

NS

N

R

NS

B

aby

Pro

du

cts

NR

N

S

NR

N

S

NR

N

S

NR

N

S

NR

N

S

NR

N

S


39

Tab

le 5

b. C

urre

nt a

md

hist

oric

al fr

eque

ncy

and

conc

entr

atio

n of

use

acc

ordi

ng to

dur

atio

n an

d ty

pe o

f exp

osur

e -

pre

viou

sly

revi

ewed

ingr

edie

nts

#

of

Use

s C

onc.

of

Use

(%

) #

of

Use

s C

onc.

of

Use

(%

) #

of

Use

s C

onc.

of

Use

(%

) #

of

Use

s C

onc.

of

Use

(%

)

C

arth

amus

Tin

ctor

ius

(Saf

flow

er)

See

d O

il E

laei

s G

uine

ensi

s (P

alm

) O

il E

laei

s G

uine

ensi

s (P

alm

) K

erne

l Oil

Hyd

roge

nate

d P

alm

Oil

dat

a ye

ar

2002

20

10

2003

20

10

1997

20

10

1997

20

10

1997

20

10

1997

20

10

1997

20

10

1997

20

10

Tot

als

142

508

0.00

005-

84

NS

36

27

2 **

0.

002-

48

11

77

**

0.05

-23

13

152

**

0.2-

30

Dur

atio

n of

Use

Le

ave

-On

114

4

02

0.0

000

5-

84

NS

2

8 1

71

**

0.0

08-1

3 9

60

**

0.8

-3

13

134

**

0

.2-3

0

Rin

se O

ff

28

106

0

.001

-72

NS

8

101

**

0

.002

-48

2 1

7 **

0

.05

-23

NR

1

8 **

2

Exp

osur

e T

ype

Eye

Are

a

5 1

5 1

-6

NS

N

R

12

**

0.0

4-2

N

R

10

**

0.8

1

61

**

0.2

-30

Pos

sib

le In

gest

ion

1

8 8

3 0

.1-6

0 N

S

NR

1

1 **

2

NR

6

**

NR

3

12

**

2-3

0

Inh

ala

tion

3 5

5 N

S

1 3

**

NR

N

R

NR

**

N

R

NR

N

R

**

1

Der

ma

l Con

tact

1

13

395

0

.001

-72

NS

3

6 2

29

**

0.0

02-4

8 1

1 7

1 **

0

.05

-2

12

123

**

0

.4-3

0

Deo

dor

an

t (u

nder

arm

) N

R

NR

N

R

NS

N

R

NR

**

N

R

NR

N

R

**

NR

N

R

NR

**

N

R

Ha

ir -

Non

-Col

orin

g 2

8 7

9 0

.000

05

-2

7 N

S

NR

4

3 **

2

-34

NR

6

**

0.9

-23

NR

N

R

**

NR

Ha

ir-C

olor

ing

NR

2

0 1

NS

N

R

NR

**

N

R

NR

N

R

**

NR

N

R

NR

**

N

R

Na

il 1

32

84

NS

N

R

NR

**

N

R

NR

N

R

**

3 N

R

NR

**

N

R

Muc

ous

Mem

bra

ne

NR

3

1 N

R

NS

7

68

**

0.0

02-4

8 N

R

10

**

0.0

5 N

R

17

**

2

Ba

th P

rodu

cts

NR

3

7 N

S

NR

N

R

**

NR

N

R

1 **

N

R

NR

N

R

**

NR

Bab

y P

rod

uct

s N

R

6 1

0 N

S

1 2

**

NR

N

R

NR

**

N

R

NR

N

R

**

NR

H

ydro

gena

ted

Pal

m K

erne

l Oil

Gos

sypi

um H

erba

ceum

(C

otto

n) S

eed

Oil

Hyd

roge

nate

d C

otto

nsee

d O

il O

ryza

Sat

iva

(Ric

e) B

ran

Oil

dat

a ye

ar

199

7 2

010

199

7 2

010

199

8 2

010

199

8 2

010

199

8 2

010

199

8 2

010

200

2 2

010

200

0-

200

3 2

010

Tot

als

29

47

**

0.4-

13

4 83

0.00

4-32

27

2 36

2 **

0.

001-

24

39

371

0.1-

39

0.00

03-7

8

Dur

atio

n of

Use

**

Le

ave

-On

27

45

**

0.4

-13

1 6

8 0

.08

-32

272

3

58

**

0.0

01-2

4 3

2 2

67

0.1

-8

0.0

003

-78

Rin

se-O

ff

2 2

**

0.6

-2

3 1

5 **

0

.004

-29

NR

4

**

0.0

1-0

.1

7 1

04

0.2

-39

0.0

05-6

Exp

osur

e T

ype

**

Eye

Are

a

5 2

**

2-1

0 N

R

4

0.1

-11

116

1

55

**

0.5

-24

NR

5

0.1

-1

0.5

-0.8

Pos

sib

le In

gest

ion

2

5 **

3

-13

NR

9

**

0.2

-1

151

N

R

**

8-1

2 N

R

17

0.1

-1

0.1

-8

Inh

ala

tion

NR

1

**

NR

N

R

12

**

0.2

N

R

NR

**

N

R

NR

1

1 N

R

0.1

Der

ma

l Con

tact

2

4 4

7 **

0

.4-1

3 4

78

**

0.0

04-2

9 1

56

356

**

0

.001

-24

36

321

0

.1-3

9 0

.000

3-2

7

Deo

dor

an

t (u

nder

arm

) N

R

NR

**

N

R

NR

1

**

0.2

N

R

NR

**

N

R

NR

N

R

NR

0

.5

Ha

ir -

Non

-Col

orin

g N

R

NR

**

N

R

NR

2

**

NR

N

R

4 **

0

.01

-0.1

3

33

0.3

0

.005

-0.5

Ha

ir-C

olor

ing

NR

N

R

**

NR

N

R

NR

**

N

R

NR

N

R

**

NR

N

R

NR

N

R

0.3

Na

il N

R

NR

**

N

R

NR

1

**

0.5

-32

NR

N

R

**

NR

2

5 N

R

0.0

2-7

8

Muc

ous

Mem

bra

ne

2 2

**

0.9

-2

NR

7

**

0.0

04-

0.0

1 N

R

NR

**

N

R

NR

4

8 1

0.0

006

-6

Ba

th P

rodu

cts

NR

N

R

**

NR

N

R

NR

**

N

R

NR

N

R

**

NR

1

17

,1-3

9 0

.2

Bab

y P

rod

uct

s N

R

NR

**

N

R

NR

N

R

**

NR

N

R

8 **

N

R

NR

1

NR

N

R

NR

- n

ot r

epor

ted

to th

e V

CR

P o

r th

e C

oun

cil

** c

once

ntra

tion

of u

se d

ata

wer

e n

ot g

iven

in th

e or

igin

al r

epor

t


40

Tab

le 5

b. C

urre

nt a

md

hist

oric

al fr

eque

ncy

and

conc

entr

atio

n of

use

* ac

cord

ing

to d

urat

ion

and

type

of e

xpos

ure

- p

revi

ousl

y re

view

ed in

gred

ient

s (c

ontin

ued)

# o

f U

ses

Con

c. o

f U

se (

%)

# o

f U

ses

Con

c. o

f U

se (

%)

# o

f U

ses

Con

c. o

f U

se (

%)

# o

f U

ses

Con

c. o

f U

se (

%)

O

ryza

Sat

iva

(Ric

e) G

erm

Oil

Ses

amum

Indi

cum

(S

esam

e) S

eed

Oil

Ses

amum

Indi

cum

(S

esam

e) O

il U

nsap

onifi

able

s Z

ea M

ays

(Cor

n) O

il

dat

a ye

ar

200

2 2

010

200

0-

200

3 2

010

198

7 2

010

198

7 2

010

198

7 2

010

198

7 2

010

200

7 2

010

200

6 2

010

Tot

als

6 34

0.

1 0.

003-

3 25

3 48

0 ≤1

- >

50

NS

N

R

17

NR

N

S

498

598

0.00

003-

14

NS

Dur

atio

n of

Use

Le

ave

-On

5 2

9 0

.1

0.0

03-3

3

5 3

74 ≤1

- >

50

NS

N

R

17

NR

N

S

241

3

61

0.0

000

3-

14

NS

Rin

se O

ff

1 5

NR

0

.003

-3

218

1

06 ≤1

- >

50

NS

N

R

NR

N

R

NS

2

57

237

0

.001

-0

.07

NS

Exp

osur

e T

ype

Eye

Are

a

NR

2

NR

0

.01

-1

6 1

4 ≤1

- >

50

NS

N

R

NR

N

R

NS

3

9 3

5 0

.000

8-

0.2

N

S

Pos

sib

le In

gest

ion

N

R

4 N

R

0.1

-3

59

52

≤1

- 1

0 N

S

NR

1

1 N

R

NS

2

9 3

0 0

.003

-10

NS

Inh

ala

tion

NR

N

R

NR

N

R

NR

5

NR

N

S

NR

N

R

NR

N

S

1 1

0.0

01-0

.1

NS

Der

ma

l Con

tact

6

32

0.1

0

.003

-3

233

4

14

≤1

-50

NS

NR

1

7 N

R

NS

2

76

371

0

.000

03

-1

4 N

S

Deo

dor

an

t (u

nder

arm

) N

R

NR

N

R

0.0

03

NR

N

R

NR

N

S

NR

N

R

NR

N

S

1 4

NR

N

S

Ha

ir -

Non

-Col

orin

g N

R

NR

N

R

NR

1

1 5

9 ≤1

-50

NS

NR

N

R

NR

N

S

38

40

0.0

001

-0

.02

NS

Ha

ir-C

olor

ing

NR

N

R

NR

N

R

NR

N

R

NR

N

S

NR

N

R

NR

N

S

182

1

83

0.0

04-

0.0

07

NS

Na

il N

R

NR

N

R

NR

3

7 ≤1

-10

NS

NR

N

R

NR

N

S

1 3

0.0

01-5

N

S

Muc

ous

Mem

bra

ne

NR

1

NR

0

.003

-0

.005

N

R

28

NR

N

S

NR

N

R

NR

N

S

2 2

0.0

04-

0.0

1 N

S

Ba

th P

rodu

cts

NR

1

NR

0

.5

3 5

1-5

0 N

S

NR

N

R

NR

N

S

NR

N

R

0.0

01-

0.0

1 N

S

Bab

y P

rod

uct

s N

R

NR

N

R

NR

2

3 1

-50

NS

N

R

NR

N

R

NS

8

8 0

.004

N

S

NR

- n

ot r

epor

ted

to th

e V

CR

P o

r th

e C

oun

cil

** c

once

ntr

atio

n o

f use

dat

a w

ere

not

giv

en in

the

orig

ina

l rep

ort


41

T

able

5b.

Cur

rent

am

d hi

stor

ical

freq

uenc

y an

d co

ncen

trat

ion

of u

se*

acco

rdin

g to

dur

atio

n an

d ty

pe o

f exp

osur

e -

pre

viou

sly

revi

ewed

ingr

edie

nts

(con

tinue

d)

#

of

Use

s C

onc.

of

Use

(%

) #

of

Use

s C

onc.

of

Use

(%

) #

of

Use

s C

onc.

of

Use

(%

) #

of

Use

s C

onc.

of

Use

(%

)

Z

ea M

ays

(Cor

n) G

erm

Oil

Z

ea M

ays

(Cor

n) O

il U

nsap

onifi

able

s P

erse

a G

ratis

sim

a (A

voca

do)

Oil

Trit

icum

Vul

gare

(W

heat

) G

erm

Oil

dat

a ye

ar

200

7 2

010

200

6 2

010

200

7 2

010

200

6 2

010

200

1 2

010

200

1 2

010

200

1 2

010

200

1 2

010

Tot

als

37

53

0.2-

25

NS

7

1 N

R

NS

18

8 88

3 0.

001-

23

0.00

01-9

8 30

3 52

7 0.

0000

2-18

0.

0001

-28

Dur

atio

n of

Use

Le

ave

-On

25

34

3-2

5 N

S

6 1

NR

N

S

40

657

0

.001

-23

0.0

005

-98

80

373

0

.000

02

-1

8 0

.000

1-2

8

Rin

se-O

ff

12

19

0.2

-3

NS

1

NR

N

R

NS

1

48

226

0

.1-5

0

.000

1-1

5 2

23

154

0

.000

02

-5

0.0

01-2

Exp

osur

e T

ype

Eye

Are

a

NR

N

R

NR

N

S

NR

N

R

NR

N

S

8 2

4 0

.1-3

0

.05

-2

9 1

2 0

.000

04

-3

0.0

001

-0.5

Pos

sib

le In

gest

ion

N

R

NR

N

R

NS

N

R

NR

N

R

NS

2

9 6

0 0

.7-2

1 0

.05

-26

33

29

0.1

-3

0.3

-5

Inh

ala

tion

NR

N

R

NR

N

S

NR

N

R

NR

N

S

2 1

1 0

.02

-3

0.0

1-8

2

7 0

.000

2-

0.0

1 0

.000

1-0

.00

05

Der

ma

l Con

tact

3

1 5

0 3

-25

NS

7

1 N

R

NS

1

65

685

0

.001

-23

0.0

005

--98

2

20

360

0

.000

02

-1

8 0

.000

5-2

3

Deo

dor

an

t (u

nder

arm

) N

R

NR

N

R

NS

N

R

NR

N

R

NS

N

R

NR

N

R

0.1

N

R

NR

0

.02

NR

Ha

ir -

Non

-Col

orin

g 4

3 0

.2

NS

N

R

NR

N

R

NS

1

1 1

89

0.0

02-3

0

.000

1-4

1 6

3 1

42

0.0

001

-2

0.0

001

-<1

Ha

ir-C

olor

ing

NR

N

R

NR

N

S

NR

N

R

NR

N

S

8 N

R

NR

0

.3

12

20

0.1

0

.01

-0.2

Na

il N

R

NR

N

R

NS

N

R

NR

N

R

NS

4

7 0

.4-1

9 0

.001

-34

4 2

0.1

-4

0.1

-28

Muc

ous

Mem

bra

ne

4 3

3 N

S

NR

N

R

NR

N

S

NR

4

3 0

.1-5

0

.002

-3

3 2

2 0

.02

-1

0.0

1-0

.5

Ba

th P

rodu

cts

3 4

NR

N

S

NR

N

R

NR

N

S

5 2

5 0

.1-5

0

.6-6

1

2 0

.001

-2

0.5

Bab

y P

rod

uct

s 2

4 N

R

NS

N

R

NR

N

R

NS

N

R

9 N

R

NR

1

9 0

.5

NR

NR

- n

ot r

epor

ted

to th

e V

CR

P o

r th

e C

oun

cil

** c

once

ntr

atio

n o

f use

dat

a w

ere

not

giv

en in

the

orig

ina

l rep

ort


42

Table 5c. Ingredients not reported to be used

Brassica Campestris (Rapeseed) Oil Unsaponifiables Potasium Rapeseedate Rapeseed Acid Sodium Rapeseedate Hydroganted Safflower Seed Oil Potassium Safflowerate Safflower Acid Sodium Safflowerate Elaeis Guineensis (Palm) Butter Hydrogenated Palm Acid Potassium Hydrogenated Palmate Sodium Hydrogenated Palmate Soy Acid Potassium Soyate Sodium Soyate Cottonseed Acid Sunflower Seed Acid Olive Acid Rice Bran Acid Hydrogenated Rice Bran Oil Oryza Sativa (Rice) Seed Oil Hydrogenated Sesame Seed Oil Sodium Sesameseedate Sesamum Indicum (Sesame) Seed Butter Corn Acid Potassium Cornate Adansonia Digitata Seed Oil Hydrogenated Adansonia Digitata Seed Oil Amaranthus Hypochondriacus Seed Oil Arctium Lappa Seed Oil Hydrogenated Argania Spinosa Kernel Oil Hydrogenated Camelina Sativa Seed Oil Citrus Aurantifolia (Lime) Seed Oil Citrus Aurantifolia (Lime) Seed Oil Unsaponifiables Hydrogenated Lime Seed Oil Hydrogenated Lime Seed Oil Unsaponifiables Citrus Aurantium Dulcis (Orange) Seed Oil Citrus Aurantium Dulcis (Orange) Seed Oil Unsaponifiables Hydrogenated Orange Seed Oil Hydrogenated Orange Seed Oil Unsaponifiables Citrus Grandis (Grapefruit) Seed Oil Unsaponifiables Hydrogenated Grapefruit Seed Oil

Hydrogenated Grapefruit Seed Oil Unsaponifiables Citrus Limon (Lemon) Seed Oil Coix Lacryma-Jobi (Job's Tears) Seed Oil Hydrogenated Pumpkin Seed Oil Cynara Cardunculus Seed Oil [Artichoke] Fragaria Ananassa (Strawberry) Seed Oil Fragaria Chiloensis (Strawberry) Seed Oil Fragaria Vesca (Strawberry) Seed Oil Fragaria Virginiana (Strawberry) Seed Oil Guizotia Abyssinica Seed Oil [Ramtil] Hydrogenated Meadowfoam Seed Oil Babassu Acid Potassium Babassuate Hydrogenated Apricot Kernel Oil Hydrogenated Apricot Kernel Oil Unsaponifiables Prunus Armeniaca (Apricot) Kernel Oil Unsaponifiables Hydrogenated Peach Kernel Oil Hydrogenated Black Currant Seed Oil Ribes Rubrum (Currant) Seed Oil Hydrogenated Raspberry Seed Oil Sodium Cocoa Butterate Sodium Theobroma Grandiflorum Seedate Torreya Nucifera Seed Oil [Kaya] Hydrogenated Wheat Germ Oil Hydrogenated Wheat Germ Oil Unsaponifiables Triticum Aestivum (Wheat) Germ Oil Hydrogenated Cranberry Seed Oil Vitis Vinifera (Grape) Seed Oil Sodium Grapeseedate Hydrogenated Grapeseed Oil Bassia Butyracea Seed Butter Brassica Napus Seed Oil [Rapeseed] Brassica Oleracea Acephala Seed Oil [Kale] Hippophae Rhamnoides Seed Oil [Sea-Buckthorn] Lupinus Albus Oil Unsaponifiables Morinda Citrifolia Seed Oil [Noni] Hydrogenated Passiflora Edulis Seed Oil Hydrogenated Punica Granatum Seed Oil Hydrogenated Rosa Canina Fruit Oil Rubus Chamaemorus Seed Oil [Cloudberry] Vaccinium Corymbosum (Blueberry) Seed Oil Vanilla Planifolia Fruit Oil [Vanilla]


43

5d. Ingredients for which concentration of use information has not yet been provided

Carthamus Tinctorius Safflower Seed Oil Oryza Sativea (Rice) Germ Oil Sesamum Indicum (Sesame) Seed Oil Hydrogenated Sesame Seed Oil Sesamum Indicum (Sesame) Oil Unsaponifiables Sodium Sesameseedate Zea Mays (Corn) Oil Zea Mays (Corn) Germ Oil Zea Mays (Corn) Oil Unsaponifiables Corn Acid Potassium Cornate Orgibnuya Cohune Seed Oil [Cohune] Plukenetia Volubilis Seed Oil [Sacha Inchi] Triticum Vulgare (Wheat) Germ Oil Unsaponifiables Bassia Butyracea Seed Butter Bassia Latifolia Seed Butter [Mahwa] Brassica Napus Seed Oil [Rapeseed] Brassica Oleracea Acephala Seed Oil [Kale] Camellia Kissi Seed Oil [Tea] Crambe Abyssinica Seed Oil [Abyssinian Mustard]

Garcinia Indica Seed Butter [Kokum] Hippophae Rhamnoides Fruit Oil [Sea-Buckthorn] Hippophae Rhamnoides Oil [Sea-Buckthorn] Hippophae Rhamnoides Seed Oil [Sea-Buckthorn] Luffa Cylindrica Seed Oil [Luffa] Lupinus Albus Seed Oil [White Lupine] Lupinus Albus Oil Unsaponifiables Lycium Barbarum Seed Oil [Goji Berry] Morinda Citrifolia Seed Oil [Noni] Orbignya Speciosa Kernel Oil [Babassu] Passiflora Edulis Seed Oil [Passion Fruit] Hydrogenated Passiflora Edulis Seed Oil Punica Granatum Seed Oil [Pomegrante] Hydrogenated Punica Granatum Seed Oil Rosa Canina Fruit Oil [Dog Rose] Hydrogenated Rosa Canina Fruit Oil Rubus Chamaemorus Seed Oil [Cloudberry] Vaccinium Corymbosum (Blueberry) Seed Oil Vaccinium Myrtillus Seed Oil [Bilberry] Vaccinium Vitis-Idaea Seed Oil [Ligonberry] Vanilla Planifolia Fruit Oil [Vanilla]


44

Tab

le 6

. N

on-f

ood,

non

-cos

met

ic u

ses

of e

dibl

e oi

ls.

3

Oil

Use

ra

pes

eed

/can

ola

ru

bber

add

itive

· l

ub

rican

ts · f

at l

iqu

orin

g of

lea

ther

· va

rnis

hes

and

lacq

uer

s · t

extil

e ch

emic

als

· det

erge

nt

add

itive

s · p

last

iciz

ers ·

we

ed c

ontr

ol · m

edic

ina

l pro

cedu

res

sun

flow

er

ma

nufa

ctu

ring

of la

cqu

ers,

cop

olym

ers,

pol

yest

er

film

s, m

odifi

ed r

esin

s, p

last

iciz

ers,

alk

yld

res

ins,

oth

er s

imila

r p

rod

ucts

pa

lm

cra

yon

and

ca

ndle

man

ufa

ctu

ring · t

in p

late

indu

stry

pa

l m k

ern

el

det

erge

nt

pro

duct

ion ·

ph

arm

ace

utic

al · c

rayo

n a

nd c

and

le m

anu

fact

urin

g · t

in p

late

indu

stry

nig

er

pai

nt ·

lub

rica

nt · p

ha

rma

ceut

ica

l ol

ive

te

xtile

ind

ust

ry · p

ha

rmac

eutic

al

coco

a p

harm

ace

utic

al

gra

pes

eed

su

bst

itute

for

linse

ed o

il in

the

ma

nufa

ctu

re o

f pai

nts

, an

d va

rnis

hes

per

illa

su

bst

itute

for

linse

ed o

il in

the

ma

nufa

ctu

re o

f pai

nts

, va

rnis

hes

, lin

oleu

m, o

ilclo

thes

, an

d p

rintin

g in

ks

fals

e fla

x d

ryin

g oi

l · m

anu

fact

urin

g of

va

rnis

hes

and

pa

ints

wa

term

elon

ill

um

ina

tion

ap

ricot

p

harm

ace

utic

al

coh

une

ma

nufa

ctu

ring

of s

oap

s, c

and

les,

an

d n

ight

light

s · c

otto

n d

yein

g · oi

ntm

ent b

ase

· s

ubst

itute

for

coco

a b

utte

r in

fo

od

linse

ed

ma

nufa

ctu

ring

of li

nol

eum

, cl

oth

oil,

prin

ting

and

lith

ogra

phi

c in

ks,

core

oils

, lin

ings

, pac

kin

gs,

oil-m

odifi

ed

alk

yd r

esin

s, c

aulk

ing

com

pou

nds,

put

ties,

lea

ther

-fin

ishi

ng

com

pou

nds,

lub

rica

nts,

gre

ase

s, p

olis

hes

, p

yrot

ech

nic

com

pos

ition

s · pig

men

t bin

der

in p

etro

chem

ica

ls ·

con

cret

e p

rote

ctor

· s

tab

ilize

r/p

last

iciz

er fo

r vi

nyl

p

last

ics ·

ind

ustr

ial s

tain

s · ju

te t

extil

es · d

ryin

g oi

l in

pain

ts a

nd v

arn

ish

es


45

Tab

le 7

. Clin

ical

irrit

atio

n an

d se

nsiti

zatio

n st

udie

s on

veg

etab

le o

ils.

Ingr

edie

nt a

nd C

once

ntra

tion

Sub

ject

s C

ompl

eted

M

etho

d R

esul

ts

Ref

eren

ce

0.0

1% A

dan

soni

a D

igita

ta S

eed

Oil

[Ba

oba

b] in

a li

p p

rod

uct

106

H

RIP

T w

ith 0

.2 g

test

ma

teria

l, se

mi-o

cclu

ded

n

ot a

der

ma

l irr

itatio

n o

r se

nsi

tizer

11

6

100

% A

da

nso

nia

Dig

itata

See

d O

il [B

aob

ab]

107

H

RIP

T w

ith 0

.02

-0.0

5 m

l tes

t m

ate

rial,

sem

i-oc

clu

ded

n

ot a

der

ma

l irr

itant

or

sen

sitiz

er

117

1%

Ast

roca

ryu

m M

uru

mu

ru S

eed

But

ter

[Mu

rum

uru

] in

a li

pst

ick

97

HR

IPT

with

15

0 m

g te

st m

ater

ial,

sem

i-occ

lud

ed

not

a d

erm

al i

rrita

tion

or

sen

sitiz

er

118

4% A

stro

cary

um

Mu

rum

uru

See

d B

utte

r in

a li

pst

ick

108

H

RIP

T,

occl

ud

ed

not

a d

erm

al i

rrita

nt o

r se

nsi

tizer

11

9

4%

Ast

roca

ryu

m M

uru

mu

ru S

eed

But

ter

in a

lip

stic

k 1

08

HR

IPT

, oc

clu

ded

n

ot a

der

ma

l irr

itant

or

sen

sitiz

er

120

4%

Ast

roca

ryu

m M

uru

mu

ru S

eed

But

ter

in a

lip

stic

k 1

08

HR

IPT

, oc

clu

ded

n

ot a

der

ma

l irr

itant

or

sen

sitiz

er

121

4%

Ast

roca

ryu

m M

uru

mu

ru S

eed

But

ter

in a

lip

stic

k 1

06

HR

IPT

, oc

clu

ded

n

ot a

der

ma

l irr

itant

or

sen

sitiz

er

122

4%

Ast

roca

ryu

m M

uru

mu

ru S

eed

But

ter

in a

lip

stic

k 1

06

HR

IPT

, oc

clu

ded

n

ot a

der

ma

l irr

itant

or

sen

sitiz

er

123

4%

Ast

roca

ryu

m M

uru

mu

ru S

eed

But

ter

in a

lip

stic

k 1

08

HR

IPT

, oc

clu

ded

n

ot a

der

ma

l irr

itant

or

sen

sitiz

er

124

3%

Ave

na

Sat

iva

(O

at)

Ker

ne

l Oil

in a

bod

y a

nd h

and

fo

rmu

latio

n 1

00

HR

IPT

with

0.2

ml,

occl

uded

n

ot a

der

ma

l irr

itant

or

sen

sitiz

er

125

1%

Bor

ago

Offi

cin

alis

See

d O

il in

a b

ody

an

d h

and

fo

rmu

latio

n 2

13

HR

IPT

with

0.2

g, o

cclu

ded

n

ot a

der

ma

l irr

itant

or

sen

sitiz

er

126

5%

Hyd

roge

na

ted

Rap

esee

d O

il in

a b

ab

y oi

l 1

05

HR

IPT

with

0.2

ml,

sem

i-occ

lud

ed

not

a d

erm

al i

rrita

nt o

r se

nsi

tizer

12

7

0.5

% B

rass

ica

Ole

race

a It

alic

a (

Bro

ccol

i) S

eed

Oil

in a

h

air

cond

ition

er

102

H

RIP

T w

ith 1

50

µl o

f tes

t mat

eria

l, 10

% d

ilutio

n,

sem

i-occ

lud

ed

not

a d

erm

al i

rrita

tion

or

sen

sitiz

er

128

0.0

985

% C

amel

lia S

inen

sis

See

d O

il in

a li

pst

ick

108

H

RIP

T w

ith 0

.2 g

, occ

lud

ed

not

a d

erm

al i

rrita

nt o

r se

nsi

tizer

12

9

0.0

985

% C

amel

lia S

inen

sis

See

d O

il in

a li

pst

ick

108

H

RIP

T w

ith 0

.2 g

, occ

lud

ed

not

a d

erm

al i

rrita

nt o

r se

nsi

tizer

13

0

74.

7% C

anol

a O

il in

a b

ody

oil

101

H

RIP

T w

ith 1

50

µl t

est

ma

teria

l, se

mi-o

cclu

ded

n

ot a

der

ma

l irr

itant

or

sen

sitiz

er

131

0.1

% C

ary

oca

r B

raili

nes

e F

ruit

Oil

in a

lip

stic

k 1

00

HR

IPT

with

20

0 m

g te

st m

ater

ial,

sem

i-occ

lud

ed

not

a d

erm

al i

rrita

nt o

r se

nsi

tizer

13

2

2%

Citr

ullu

s La

nat

us

(Wa

term

elon

) S

eed

Oil

in a

faci

al

oil

105

H

RIP

T,

sem

i-occ

lud

ed

not

a d

erm

al i

rrita

nt o

r se

nsi

tizer

13

3

0.5

% E

uter

pe

Ole

race

a F

ruit

Oil

in a

n e

ye t

rea

tmen

t 1

04

HR

IPT

with

15

0 µ

l tes

t m

ate

rial,

sem

i-occ

lud

ed

not

a d

erm

al i

rrita

nt o

r se

nsi

tizer

13

4

0.1

9% G

lyci

ne

Soj

a (

Soy

bea

n)

Un

sapo

nifi

able

s in

a fa

ce

and

nec

k p

rodu

ct

50

HR

IPT

, oc

clu

ded

n

ot a

der

ma

l irr

itatio

n o

r se

nsi

tizer

13

5


46

Tab

le 7

. Clin

ical

irrit

atio

n an

d se

nsiti

zatio

n st

udie

s on

veg

etab

le o

ils.

Ingr

edie

nt a

nd C

once

ntra

tion

Sub

ject

s C

ompl

eted

M

etho

d R

esul

ts

Ref

eren

ce

39%

Hyd

roge

na

ted

Soy

bea

n O

il in

a li

pst

ick

108

H

RIP

T,

occl

ud

ed

not

a d

erm

al i

rrita

nt o

r se

nsi

tizer

13

6

2%

Hel

ian

thu

s A

nnu

us

(Sun

flow

er)

See

d O

il U

nsa

pon

ifiab

les

in a

nig

ht p

rodu

ct

100

H

RIP

T,

sem

i-occ

lud

ed

not

a d

erm

al i

rrita

tion

or

sen

sitiz

er

135

2% H

elia

nth

us

An

nuu

s (S

unflo

wer

) S

eed

Oil

Un

sap

onifi

able

s in

a fa

ce a

nd

nec

k p

rod

uct

1

00

HR

IPT

, se

mi-o

cclu

ded

n

ot a

der

ma

l irr

itatio

n o

r se

nsi

tizer

13

5

0.3

1% Ir

vin

gia

Ga

nen

sis

Ker

nel

Bu

tter

[D

ika]

in a

face

a

nd n

eck

pro

duct

5

2 H

RIP

T,

occl

ud

ed

not

a d

erm

al i

rrita

tion

or

sen

sitiz

er

135

71.

3% L

imn

anth

es A

lba

(M

ead

owfo

am

) S

eed

Oil

in a

fa

cia

l rep

air

pro

duct

1

09

HR

IPT

, se

mi-o

cclu

ded

7 s

ubj

ects

ha

d + o

n th

e fir

st d

ay

of t

he

ind

uctio

n o

nly

, n

o ot

her

rea

ctio

ns.

Not

a

der

ma

l irr

itant

or

sen

sitiz

er.

137

9.4

% L

inu

m U

sita

tissi

mu

m (

Lin

seed

) S

eed

Oil

in

ma

sca

ra

105

H

RIP

T w

ith 0

.2 g

test

ma

teria

l, se

mi-o

cclu

ded

n

ot a

der

ma

l irr

itatio

n o

r se

nsi

tizer

13

8

3.8

7% M

angi

fera

Ind

ica

(Man

go)

See

d O

il in

an

eye

liner

1

02

HR

IPT

with

0.2

g o

f tes

t m

ate

rial,

sem

i-occ

lud

ed

not

a d

erm

al i

rrita

nt o

r se

nsi

tizer

13

9

2%

Ma

ngi

fera

Ind

ica

(M

an

go)

See

d O

il in

a li

pst

ick

100

H

RIP

T w

ith 1

50

µl t

est

ma

teria

l, se

mi-o

cclu

ded

n

ot a

der

ma

l irr

itant

or

sen

sitiz

er

140

9%

Ma

ngi

fera

Ind

ica

(M

an

go)

See

d B

utte

r in

a b

ody

pro

duc

t 1

02

HR

IPT

with

0.2

g, s

emi-o

cclu

ded

n

ot a

sen

sitiz

er

141

1%

Ma

ngi

fera

Ind

ica

(M

an

go)

See

d B

utte

r in

a fa

cia

l lo

tion

1

00

HR

IPT

with

20

0 µ

l tes

t m

ate

rial,

sem

i-occ

lud

ed

not

a d

erm

al i

rrita

nt o

r se

nsi

tizer

14

2

3%

Mor

inga

Pte

rygo

sper

na

See

d O

il in

an

eye

tre

atm

ent

104

H

RIP

T w

ith 1

50

µl t

est

ma

teria

l, se

mi-o

cclu

ded

not

a d

erm

al i

rrita

nt o

r se

nsi

tizer

14

3

1.9

9% O

enot

her

a B

ienn

is (

Eve

nin

g P

rimro

se)

Oil

in a

fo

un

datio

n 6

00

HR

IPT

, oc

clu

ded

n

ot a

der

ma

l irr

itant

or

sen

sitiz

er

144

22%

Ole

a E

uro

pa

ea (

Oliv

e) F

ruit

Oil

in a

bod

y m

oist

uriz

er

105

H

RIP

T,

sem

i-occ

lud

ed

not

a d

erm

al i

rrita

nt o

r se

nsi

tizer

14

5

58.

7% O

lea

Eu

rop

aea

(O

live)

Fru

it O

il in

a c

ondi

tioni

ng

hai

r oi

l 1

02

HR

IPT

with

0.2

ml,

sem

i-occ

lud

ed

not

a d

erm

al i

rrita

nt o

r se

nsi

tizer

14

6

5%

Hyd

roge

na

ted

Oliv

e O

il U

nsa

pon

ifia

ble

s in

a s

kin

cl

ean

sin

g p

rodu

ct

57

HR

IPT

, se

mi-o

cclu

ded

, 10%

dilu

tion

not

a d

erm

al i

rrita

tion

or

sen

sitiz

er

135

2%

Hyd

roge

na

ted

Oliv

e O

il U

nsa

pon

ifia

ble

s in

a fa

ce

and

nec

k p

rodu

ct

50

HR

IPT

, oc

clu

ded

n

ot a

der

ma

l irr

itatio

n o

r se

nsi

tizer

13

5

12%

Hyd

roge

na

ted

Oliv

e O

il in

a li

pst

ick

108

H

RIP

T,

occl

ud

ed

not

a d

erm

al i

rrita

nt o

r se

nsi

tizer

13

6

2.5

% O

lea

Eu

rop

aea

(O

live)

Oil

Un

sap

onfia

ble

s in

a

bat

h b

ody

mis

t 1

07

HR

IPT

with

15

0 µ

l tes

t m

ate

rial,

sem

i-occ

lud

ed

not

a d

erm

al i

rrita

nt o

r se

nsi

tizer

14

7


47

Tab

le 7

. Clin

ical

irrit

atio

n an

d se

nsiti

zatio

n st

udie

s on

veg

etab

le o

ils.

Ingr

edie

nt a

nd C

once

ntra

tion

Sub

ject

s C

ompl

eted

M

etho

d R

esul

ts

Ref

eren

ce

17.

64%

Sod

ium

Oliv

ate

in a

bod

y b

ar

soa

p 1

07

HR

IPT

, se

mi-o

cclu

ded

n

ot a

der

ma

l irr

itant

or

sen

sitiz

er

148

3.7

9% O

rbig

nya

Ole

ifera

Se

ed O

il in

a c

rea

m c

lea

nse

r 1

04

HR

IPT

with

0.2

ml o

f a 1

0% d

ilutio

n ,

sem

i-occ

lud

ed

not

a d

erm

al i

rrita

nt o

r se

nsi

tizer

14

9

0.0

4% P

runu

s D

omes

tica

See

d O

il in

a p

resh

ave

lotio

n 1

05

HR

IPT

with

0.2

ml,

occl

uded

n

ot a

sen

sitiz

er

150

0.2

% R

ibes

Nig

rum

(B

lack

Cu

rra

nt)

See

d O

il is

an

eye

m

ask

2

28

HR

IPT

, oc

clu

ded

4 s

ubj

ects

ha

d "?

" or

"+

" re

act

ion

du

ring

indu

ctio

n th

at w

ere

not

co

nsi

der

ed c

linic

ally

re

leva

nt,

no

oth

er r

eact

ion

s ob

serv

ed.

Not

se

nsi

tizin

g 15

1

0.2

% R

ibes

Nig

rum

(B

lack

Cu

rra

nt)

See

d O

il is

an

eye

m

ask

1

95

4-w

eek

sa

fety

in-u

se s

tud

y

No

ad

vers

e re

act

ion

s re

por

ted

. P

rod

uct

con

sid

ered

sui

tab

le fo

r se

nsi

tive

skin

. 15

2

Rub

us

Ida

eus

(Ra

spb

erry

) S

eed

Oil

in a

face

and

nec

k p

rod

uct (

conc

entr

atio

n n

ot r

epor

ted

) 1

02

HR

IPT

, oc

clu

ded

n

ot a

der

ma

l irr

itatio

n o

r se

nsi

tizer

13

5

0.0

023

% S

olan

um

Lyc

oper

sicu

m (

To

ma

to)

See

d O

il in

a

crea

m c

lea

nse

r 1

04

HR

IPT

with

0.2

ml o

f a 1

0% d

ilutio

n ,

sem

i-occ

lud

ed

not

a d

erm

al i

rrita

nt o

r se

nsi

tizer

15

3

50.

1% T

heo

bro

ma

Ca

cao

(Coc

oa)

See

d B

utte

r in

a li

p

ba

lm

106

H

RIP

T w

ith 1

50

µl t

est

ma

teria

l, se

mi-o

cclu

ded

n

ot a

der

ma

l irr

itant

or

sen

sitiz

er

154

5%

Th

eob

rom

a G

rand

iflor

um

See

d B

utte

r in

a li

p b

alm

1

06

HR

IPT

with

15

0 µ

l tes

t m

ate

rial,

sem

i-occ

lud

ed

not

a d

erm

al i

rrita

nt o

r se

nsi

tizer

15

5

0.0

4% V

acci

nium

Ma

croc

arp

on (

Cra

nber

ry)

Se

ed O

il in

a

face

and

nec

k p

rodu

ct

53

HR

IPT

, oc

clu

ded

n

ot a

der

ma

l irr

itatio

n o

r se

nsi

tizer

13

5

4%

Veg

eta

ble

Oil

in a

foun

datio

n 1

15

HR

IPT

, se

mi-o

cclu

ded

1 s

ubj

ect h

ad

+ on

the

first

da

y of

th

e in

duc

tion

on

ly,

no

oth

er r

eact

ion

s. N

ot

ad

erm

al i

rrita

nt o

r se

nsi

tizer

. 15

6

4%

Veg

eta

ble

Oil

in a

lip

stic

k 1

06

HR

IPT

with

0.2

g, o

cclu

ded

n

ot a

der

ma

l irr

itant

or

sen

sitiz

er

157

11%

Veg

eta

ble

Oil

in a

n e

ye s

ha

dow

1

06

HR

IPT

, se

mi-o

cclu

ded

n

ot a

der

ma

l irr

itant

or

sen

sitiz

er

158

39%

Viti

s V

inife

ra (

Gra

pe

)See

d O

il in

a p

resh

ave

lotio

n 1

05

HR

IPT

with

0.2

ml,

occl

uded

n

ot a

sen

sitiz

er

150

0.5

% H

ydro

gen

ate

d G

rap

esee

d O

il in

a li

p p

rodu

ct

53

HR

IPT

, se

mi-o

cclu

ded

n

ot a

der

ma

l irr

itatio

n o

r se

nsi

tizer

15

9


48

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55

145. Clinical Research Laboratories, Inc. Repeated insult patch test on a body moisturizer containing 22% Olea Europaea (Olive) Fruit Oil. Unpublished data. 2007.

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Data


2010 FDA VCRP Raw Data

VEGETABLE FATTY ACID 06A - Hair Dyes and Colors (all types requiring caution statements and patch tests) 17

VEGETABLE FATTY ACID 07E - Lipstick 3

VEGETABLE FATTY ACID 12F - Moisturizing 1

VEGETABLE OIL 01B - Baby Lotions, Oils, Powders, and Creams 1

VEGETABLE OIL 02A - Bath Oils, Tablets, and Salts 1

VEGETABLE OIL 02D - Other Bath Preparations 1

VEGETABLE OIL 03C - Eye Shadow 1

VEGETABLE OIL 03D - Eye Lotion 1

VEGETABLE OIL 03F - Mascara 2

VEGETABLE OIL 03G - Other Eye Makeup Preparations 7

VEGETABLE OIL 04E - Other Fragrance Preparation 1

VEGETABLE OIL 05F - Shampoos (non-coloring) 1

VEGETABLE OIL 06H - Other Hair Coloring Preparation 1

VEGETABLE OIL 07C - Foundations 3

VEGETABLE OIL 07E - Lipstick 71

VEGETABLE OIL 07I - Other Makeup Preparations 6

VEGETABLE OIL 08C - Nail Creams and Lotions 1

VEGETABLE OIL 10A - Bath Soaps and Detergents 1

VEGETABLE OIL 12A - Cleansing 5

VEGETABLE OIL 12C - Face and Neck (exc shave) 5

VEGETABLE OIL 12D - Body and Hand (exc shave) 7

VEGETABLE OIL 12F - Moisturizing 8

VEGETABLE OIL 12G - Night 4

VEGETABLE OIL 12H - Paste Masks (mud packs) 3

VEGETABLE OIL 12J - Other Skin Care Preps 10

VEGETABLE OIL 13A - Suntan Gels, Creams, and Liquids 3

HYDROGENATED VEGETABLE OIL 03A - Eyebrow Pencil 29

HYDROGENATED VEGETABLE OIL 03B - Eyeliner 38

HYDROGENATED VEGETABLE OIL 03C - Eye Shadow 11

HYDROGENATED VEGETABLE OIL 03D - Eye Lotion 9

HYDROGENATED VEGETABLE OIL 03F - Mascara 4

HYDROGENATED VEGETABLE OIL 03G - Other Eye Makeup Preparations 11

HYDROGENATED VEGETABLE OIL 04E - Other Fragrance Preparation 1

HYDROGENATED VEGETABLE OIL 05A - Hair Conditioner 2

HYDROGENATED VEGETABLE OIL 07B - Face Powders 1

HYDROGENATED VEGETABLE OIL 07C - Foundations 8

HYDROGENATED VEGETABLE OIL 07E - Lipstick 216

HYDROGENATED VEGETABLE OIL 07I - Other Makeup Preparations 27

HYDROGENATED VEGETABLE OIL 08B - Cuticle Softeners 1

HYDROGENATED VEGETABLE OIL 10A - Bath Soaps and Detergents 1

HYDROGENATED VEGETABLE OIL 10E - Other Personal Cleanliness Products 1

HYDROGENATED VEGETABLE OIL 12A - Cleansing 12

HYDROGENATED VEGETABLE OIL 12C - Face and Neck (exc shave) 7

HYDROGENATED VEGETABLE OIL 12D - Body and Hand (exc shave) 21

HYDROGENATED VEGETABLE OIL 12E - Foot Powders and Sprays 1

HYDROGENATED VEGETABLE OIL 12F - Moisturizing 30

HYDROGENATED VEGETABLE OIL 12G - Night 7

HYDROGENATED VEGETABLE OIL 12H - Paste Masks (mud packs) 2

HYDROGENATED VEGETABLE OIL 12J - Other Skin Care Preps 15

HYDROGENATED VEGETABLE OIL 13B - Indoor Tanning Preparations 1

HYDROGENATED VEGETABLE OIL 13C - Other Suntan Preparations 1

BRASSICA CAMPESTRIS (RAPESEED) SEED OIL 03D - Eye Lotion 1

BRASSICA CAMPESTRIS (RAPESEED) SEED OIL 03G - Other Eye Makeup Preparations 1

BRASSICA CAMPESTRIS (RAPESEED) SEED OIL 07E - Lipstick 1

BRASSICA CAMPESTRIS (RAPESEED) SEED OIL 10E - Other Personal Cleanliness Products 1

BRASSICA CAMPESTRIS (RAPESEED) SEED OIL 12A - Cleansing 3

BRASSICA CAMPESTRIS (RAPESEED) SEED OIL 12C - Face and Neck (exc shave) 4

BRASSICA CAMPESTRIS (RAPESEED) SEED OIL 12D - Body and Hand (exc shave) 9

BRASSICA CAMPESTRIS (RAPESEED) SEED OIL 12F - Moisturizing 3

BRASSICA CAMPESTRIS (RAPESEED) SEED OIL 12G - Night 1

BRASSICA CAMPESTRIS (RAPESEED) SEED OIL 12J - Other Skin Care Preps 1

BRASSICA CAMPESTRIS (RAPESEED) SEED OIL 13B - Indoor Tanning Preparations 2



HYDROGENATED RAPESEED OIL 12A - Cleansing 1

CANOLA OIL 02A - Bath Oils, Tablets, and Salts 1

CANOLA OIL 03B - Eyeliner 1

CANOLA OIL 03C - Eye Shadow 1

CANOLA OIL 03D - Eye Lotion 1

CANOLA OIL 05A - Hair Conditioner 6

CANOLA OIL 05F - Shampoos (non-coloring) 2

CANOLA OIL 05G - Tonics, Dressings, and Other Hair Grooming Aids 7

CANOLA OIL 05I - Other Hair Preparations 4

CANOLA OIL 07E - Lipstick 62

CANOLA OIL 07I - Other Makeup Preparations 4

CANOLA OIL 10A - Bath Soaps and Detergents 2

CANOLA OIL 11G - Other Shaving Preparation Products 1

CANOLA OIL 12A - Cleansing 4

CANOLA OIL 12D - Body and Hand (exc shave) 13

CANOLA OIL 12E - Foot Powders and Sprays 1

CANOLA OIL 12F - Moisturizing 15

CANOLA OIL 12G - Night 2

CANOLA OIL 12J - Other Skin Care Preps 5

HYDROGENATED CANOLA OIL 12A - Cleansing 1

HYDROGENATED CANOLA OIL 12J - Other Skin Care Preps 2

PALM KERNEL ACID 04E - Other Fragrance Preparation 1

PALM KERNEL ACID 05F - Shampoos (non-coloring) 1

PALM KERNEL ACID 10A - Bath Soaps and Detergents 61

PALM KERNEL ACID 10E - Other Personal Cleanliness Products 3

PALM KERNEL ACID 11F - Shaving Soap 2

PALM KERNEL ACID 12A - Cleansing 2

PALM KERNEL ACID 12I - Skin Fresheners 2

ELAEIS OLEIFERA KERNEL OIL 05E - Rinses (non-coloring) 1

ELAEIS OLEIFERA KERNEL OIL 05I - Other Hair Preparations 1

ELAEIS OLEIFERA KERNEL OIL 06H - Other Hair Coloring Preparation 3

PALM ACID 04E - Other Fragrance Preparation 1

PALM ACID 10A - Bath Soaps and Detergents 31

PALM ACID 12A - Cleansing 1

PALM FATTY ACID 10A - Bath Soaps and Detergents 27

PALM FATTY ACID 12A - Cleansing 2

POTASSIUM PALMATE 10A - Bath Soaps and Detergents 2

POTASSIUM PALMATE 11F - Shaving Soap 3

POTASSIUM PALM KERNELATE 10A - Bath Soaps and Detergents 1

POTASSIUM PALM KERNELATE 10E - Other Personal Cleanliness Products 3

POTASSIUM PALM KERNELATE 11F - Shaving Soap 3

SODIUM PALMATE 01C - Other Baby Products 3

SODIUM PALMATE 02D - Other Bath Preparations 1

SODIUM PALMATE 04E - Other Fragrance Preparation 1

SODIUM PALMATE 10A - Bath Soaps and Detergents 184

SODIUM PALMATE 10E - Other Personal Cleanliness Products 5



SODIUM PALMATE 11F - Shaving Soap 5

SODIUM PALMATE 12A - Cleansing 10

SODIUM PALMATE 12C - Face and Neck (exc shave) 2

SODIUM PALMATE 12H - Paste Masks (mud packs) 1

SODIUM PALM KERNELATE 01C - Other Baby Products 4

SODIUM PALM KERNELATE 02D - Other Bath Preparations 3

SODIUM PALM KERNELATE 04E - Other Fragrance Preparation 1

SODIUM PALM KERNELATE 10A - Bath Soaps and Detergents 169

SODIUM PALM KERNELATE 10E - Other Personal Cleanliness Products 4

SODIUM PALM KERNELATE 11A - Aftershave Lotion 1

SODIUM PALM KERNELATE 11F - Shaving Soap 3

SODIUM PALM KERNELATE 12A - Cleansing 5

SODIUM PALM KERNELATE 12J - Other Skin Care Preps 4

GLYCINE SOJA (SOYBEAN) OIL 01A - Baby Shampoos 1

GLYCINE SOJA (SOYBEAN) OIL 01B - Baby Lotions, Oils, Powders, and Creams 17

GLYCINE SOJA (SOYBEAN) OIL 01C - Other Baby Products 3

GLYCINE SOJA (SOYBEAN) OIL 02A - Bath Oils, Tablets, and Salts 13

GLYCINE SOJA (SOYBEAN) OIL 02B - Bubble Baths 1

GLYCINE SOJA (SOYBEAN) OIL 02D - Other Bath Preparations 5

GLYCINE SOJA (SOYBEAN) OIL 03B - Eyeliner 7

GLYCINE SOJA (SOYBEAN) OIL 03C - Eye Shadow 20

GLYCINE SOJA (SOYBEAN) OIL 03D - Eye Lotion 13

GLYCINE SOJA (SOYBEAN) OIL 03E - Eye Makeup Remover 2

GLYCINE SOJA (SOYBEAN) OIL 03F - Mascara 3

GLYCINE SOJA (SOYBEAN) OIL 03G - Other Eye Makeup Preparations 8

GLYCINE SOJA (SOYBEAN) OIL 04E - Other Fragrance Preparation 3

GLYCINE SOJA (SOYBEAN) OIL 05A - Hair Conditioner 25

GLYCINE SOJA (SOYBEAN) OIL 05B - Hair Spray (aerosol fixatives) 2

GLYCINE SOJA (SOYBEAN) OIL 05F - Shampoos (non-coloring) 19

GLYCINE SOJA (SOYBEAN) OIL 05G - Tonics, Dressings, and Other Hair Grooming Aids 23

GLYCINE SOJA (SOYBEAN) OIL 05H - Wave Sets 1

GLYCINE SOJA (SOYBEAN) OIL 05I - Other Hair Preparations 27

GLYCINE SOJA (SOYBEAN) OIL 06C - Hair Rinses (coloring) 5

GLYCINE SOJA (SOYBEAN) OIL 07A - Blushers (all types) 12

GLYCINE SOJA (SOYBEAN) OIL 07B - Face Powders 21

GLYCINE SOJA (SOYBEAN) OIL 07C - Foundations 22

GLYCINE SOJA (SOYBEAN) OIL 07E - Lipstick 103

GLYCINE SOJA (SOYBEAN) OIL 07F - Makeup Bases 3

GLYCINE SOJA (SOYBEAN) OIL 07G - Rouges 14

GLYCINE SOJA (SOYBEAN) OIL 07H - Makeup Fixatives 1

GLYCINE SOJA (SOYBEAN) OIL 07I - Other Makeup Preparations 19

GLYCINE SOJA (SOYBEAN) OIL 08B - Cuticle Softeners 2

GLYCINE SOJA (SOYBEAN) OIL 08E - Nail Polish and Enamel 2

GLYCINE SOJA (SOYBEAN) OIL 08G - Other Manicuring Preparations 2

GLYCINE SOJA (SOYBEAN) OIL 10A - Bath Soaps and Detergents 23

GLYCINE SOJA (SOYBEAN) OIL 10E - Other Personal Cleanliness Products 47

GLYCINE SOJA (SOYBEAN) OIL 11A - Aftershave Lotion 1

GLYCINE SOJA (SOYBEAN) OIL 11D - Preshave Lotions (all types) 1

GLYCINE SOJA (SOYBEAN) OIL 11E - Shaving Cream 2

GLYCINE SOJA (SOYBEAN) OIL 11G - Other Shaving Preparation Products 2

GLYCINE SOJA (SOYBEAN) OIL 12A - Cleansing 36

GLYCINE SOJA (SOYBEAN) OIL 12B - Depilatories 4

GLYCINE SOJA (SOYBEAN) OIL 12C - Face and Neck (exc shave) 50

GLYCINE SOJA (SOYBEAN) OIL 12D - Body and Hand (exc shave) 82

GLYCINE SOJA (SOYBEAN) OIL 12E - Foot Powders and Sprays 1

GLYCINE SOJA (SOYBEAN) OIL 12F - Moisturizing 152

GLYCINE SOJA (SOYBEAN) OIL 12G - Night 19

GLYCINE SOJA (SOYBEAN) OIL 12H - Paste Masks (mud packs) 7

GLYCINE SOJA (SOYBEAN) OIL 12I - Skin Fresheners 9

GLYCINE SOJA (SOYBEAN) OIL 12J - Other Skin Care Preps 49

GLYCINE SOJA (SOYBEAN) OIL 13A - Suntan Gels, Creams, and Liquids 7



GLYCINE SOJA (SOYBEAN) OIL 13B - Indoor Tanning Preparations 19

GLYCINE SOJA (SOYBEAN) OIL 13C - Other Suntan Preparations 2

EPOXIDIZED SOYBEAN OIL 08A - Basecoats and Undercoats 1

EPOXIDIZED SOYBEAN OIL 08E - Nail Polish and Enamel 3

EPOXIDIZED SOYBEAN OIL 08G - Other Manicuring Preparations 1

GLYCINE SOJA (SOYBEAN) OIL UNSAPONIFIABLES 07C - Foundations 1

GLYCINE SOJA (SOYBEAN) OIL UNSAPONIFIABLES 12C - Face and Neck (exc shave) 7

GLYCINE SOJA (SOYBEAN) OIL UNSAPONIFIABLES 12D - Body and Hand (exc shave) 1

GLYCINE SOJA (SOYBEAN) OIL UNSAPONIFIABLES 12J - Other Skin Care Preps 3

HYDROGENATED SOYBEAN OIL 03B - Eyeliner 1

HYDROGENATED SOYBEAN OIL 03C - Eye Shadow 1

HYDROGENATED SOYBEAN OIL 03D - Eye Lotion 1

HYDROGENATED SOYBEAN OIL 03G - Other Eye Makeup Preparations 1

HYDROGENATED SOYBEAN OIL 05F - Shampoos (non-coloring) 1

HYDROGENATED SOYBEAN OIL 05G - Tonics, Dressings, and Other Hair Grooming Aids 1

HYDROGENATED SOYBEAN OIL 07D - Leg and Body Paints 1

HYDROGENATED SOYBEAN OIL 07E - Lipstick 3

HYDROGENATED SOYBEAN OIL 07I - Other Makeup Preparations 3

HYDROGENATED SOYBEAN OIL 12A - Cleansing 2

HYDROGENATED SOYBEAN OIL 12C - Face and Neck (exc shave) 4

HYDROGENATED SOYBEAN OIL 12D - Body and Hand (exc shave) 7

HYDROGENATED SOYBEAN OIL 12F - Moisturizing 8

HYDROGENATED SOYBEAN OIL 12J - Other Skin Care Preps 2

HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 01A - Baby Shampoos 1

HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 01B - Baby Lotions, Oils, Powders, and Creams 16

HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 01C - Other Baby Products 1

HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 02A - Bath Oils, Tablets, and Salts 3

HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 02B - Bubble Baths 1

HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 02C - Bath Capsules 1

HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 02D - Other Bath Preparations 6

HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 03B - Eyeliner 12

HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 03C - Eye Shadow 17

HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 03D - Eye Lotion 21

HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 03F - Mascara 1

HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 03G - Other Eye Makeup Preparations 13

HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 04E - Other Fragrance Preparation 12

HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 05A - Hair Conditioner 68

HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 05B - Hair Spray (aerosol fixatives) 4

HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 05C - Hair Straighteners 3

HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 05F - Shampoos (non-coloring) 30

HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 05G - Tonics, Dressings, and Other Hair Grooming Aids 25

HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 05H - Wave Sets 1

HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 05I - Other Hair Preparations 48

HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 06A - Hair Dyes and Colors (all types requiring caution statements and patch tests) 81

HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 06G - Hair Bleaches 3

HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 06H - Other Hair Coloring Preparation 1

HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 07A - Blushers (all types) 23

HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 07B - Face Powders 7

HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 07C - Foundations 19

HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 07E - Lipstick 260

HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 07H - Makeup Fixatives 2

HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 07I - Other Makeup Preparations 19

HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 08A - Basecoats and Undercoats 1

HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 08B - Cuticle Softeners 2

HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 08C - Nail Creams and Lotions 2

HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 08G - Other Manicuring Preparations 3

HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 10A - Bath Soaps and Detergents 46

HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 10B - Deodorants (underarm) 1



HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 10E - Other Personal Cleanliness Products 52

HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 11A - Aftershave Lotion 2

HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 11E - Shaving Cream 7

HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 11G - Other Shaving Preparation Products 2

HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 12A - Cleansing 34

HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 12B - Depilatories 1

HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 12C - Face and Neck (exc shave) 93

HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 12D - Body and Hand (exc shave) 100

HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 12E - Foot Powders and Sprays 3

HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 12F - Moisturizing 225

HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 12G - Night 25

HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 12H - Paste Masks (mud packs) 19

HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 12I - Skin Fresheners 2

HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 12J - Other Skin Care Preps 76

HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 13A - Suntan Gels, Creams, and Liquids 4

HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 13B - Indoor Tanning Preparations 9

HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL 13C - Other Suntan Preparations 6

HYBRID SUNFLOWER SEED OIL 07E - Lipstick 1

HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL UNSAPONIFIABLES03B - Eyeliner 1

HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL UNSAPONIFIABLES12C - Face and Neck (exc shave) 1

HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL UNSAPONIFIABLES12G - Night 1

HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL UNSAPONIFIABLES13A - Suntan Gels, Creams, and Liquids 2

HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL UNSAPONIFIABLES13B - Indoor Tanning Preparations 1

SUNFLOWER OIL, UNSAPONIFIABLE FRACTION 03G - Other Eye Makeup Preparations 1

SUNFLOWER OIL, UNSAPONIFIABLE FRACTION 12D - Body and Hand (exc shave) 1

SUNFLOWER OIL, UNSAPONIFIABLE FRACTION 12I - Skin Fresheners 1

SUNFLOWER OIL, UNSAPONIFIABLE FRACTION 13A - Suntan Gels, Creams, and Liquids 1

OLEA EUROPAEA (OLIVE) FRUIT OIL 01B - Baby Lotions, Oils, Powders, and Creams 7

OLEA EUROPAEA (OLIVE) FRUIT OIL 01C - Other Baby Products 2

OLEA EUROPAEA (OLIVE) FRUIT OIL 02A - Bath Oils, Tablets, and Salts 7

OLEA EUROPAEA (OLIVE) FRUIT OIL 02D - Other Bath Preparations 7

OLEA EUROPAEA (OLIVE) FRUIT OIL 03B - Eyeliner 1

OLEA EUROPAEA (OLIVE) FRUIT OIL 03C - Eye Shadow 3

OLEA EUROPAEA (OLIVE) FRUIT OIL 03D - Eye Lotion 6

OLEA EUROPAEA (OLIVE) FRUIT OIL 03F - Mascara 9

OLEA EUROPAEA (OLIVE) FRUIT OIL 03G - Other Eye Makeup Preparations 7

OLEA EUROPAEA (OLIVE) FRUIT OIL 04A - Cologne and Toilet waters 2

OLEA EUROPAEA (OLIVE) FRUIT OIL 04E - Other Fragrance Preparation 4

OLEA EUROPAEA (OLIVE) FRUIT OIL 05A - Hair Conditioner 54

OLEA EUROPAEA (OLIVE) FRUIT OIL 05C - Hair Straighteners 8

OLEA EUROPAEA (OLIVE) FRUIT OIL 05F - Shampoos (non-coloring) 39

OLEA EUROPAEA (OLIVE) FRUIT OIL 05G - Tonics, Dressings, and Other Hair Grooming Aids 55

OLEA EUROPAEA (OLIVE) FRUIT OIL 05I - Other Hair Preparations 34

OLEA EUROPAEA (OLIVE) FRUIT OIL 07A - Blushers (all types) 9

OLEA EUROPAEA (OLIVE) FRUIT OIL 07B - Face Powders 6

OLEA EUROPAEA (OLIVE) FRUIT OIL 07C - Foundations 3

OLEA EUROPAEA (OLIVE) FRUIT OIL 07E - Lipstick 26

OLEA EUROPAEA (OLIVE) FRUIT OIL 07F - Makeup Bases 3

OLEA EUROPAEA (OLIVE) FRUIT OIL 07I - Other Makeup Preparations 10

OLEA EUROPAEA (OLIVE) FRUIT OIL 08B - Cuticle Softeners 2

OLEA EUROPAEA (OLIVE) FRUIT OIL 08C - Nail Creams and Lotions 1

OLEA EUROPAEA (OLIVE) FRUIT OIL 08E - Nail Polish and Enamel 1

OLEA EUROPAEA (OLIVE) FRUIT OIL 08G - Other Manicuring Preparations 1

OLEA EUROPAEA (OLIVE) FRUIT OIL 10A - Bath Soaps and Detergents 95

OLEA EUROPAEA (OLIVE) FRUIT OIL 10B - Deodorants (underarm) 3

OLEA EUROPAEA (OLIVE) FRUIT OIL 10E - Other Personal Cleanliness Products 26

OLEA EUROPAEA (OLIVE) FRUIT OIL 11A - Aftershave Lotion 1

OLEA EUROPAEA (OLIVE) FRUIT OIL 11B - Beard Softeners 1

OLEA EUROPAEA (OLIVE) FRUIT OIL 11E - Shaving Cream 12

OLEA EUROPAEA (OLIVE) FRUIT OIL 11F - Shaving Soap 2



OLEA EUROPAEA (OLIVE) FRUIT OIL 11G - Other Shaving Preparation Products 2

OLEA EUROPAEA (OLIVE) FRUIT OIL 12A - Cleansing 40

OLEA EUROPAEA (OLIVE) FRUIT OIL 12C - Face and Neck (exc shave) 58

OLEA EUROPAEA (OLIVE) FRUIT OIL 12D - Body and Hand (exc shave) 111

OLEA EUROPAEA (OLIVE) FRUIT OIL 12F - Moisturizing 183

OLEA EUROPAEA (OLIVE) FRUIT OIL 12G - Night 9

OLEA EUROPAEA (OLIVE) FRUIT OIL 12H - Paste Masks (mud packs) 6

OLEA EUROPAEA (OLIVE) FRUIT OIL 12J - Other Skin Care Preps 35

OLEA EUROPAEA (OLIVE) FRUIT OIL 13A - Suntan Gels, Creams, and Liquids 3

OLEA EUROPAEA (OLIVE) FRUIT OIL 13B - Indoor Tanning Preparations 18

OLEA EUROPAEA (OLIVE) FRUIT OIL 13C - Other Suntan Preparations 3

HYDROGENATED OLIVE OIL 03B - Eyeliner 1

HYDROGENATED OLIVE OIL 03C - Eye Shadow 1

HYDROGENATED OLIVE OIL 03D - Eye Lotion 1

HYDROGENATED OLIVE OIL 03F - Mascara 5

HYDROGENATED OLIVE OIL 03G - Other Eye Makeup Preparations 5

HYDROGENATED OLIVE OIL 05A - Hair Conditioner 4

HYDROGENATED OLIVE OIL 05F - Shampoos (non-coloring) 6

HYDROGENATED OLIVE OIL 05I - Other Hair Preparations 1

HYDROGENATED OLIVE OIL 07E - Lipstick 7

HYDROGENATED OLIVE OIL 10A - Bath Soaps and Detergents 1

HYDROGENATED OLIVE OIL 11F - Shaving Soap 1

HYDROGENATED OLIVE OIL 12A - Cleansing 1

HYDROGENATED OLIVE OIL 12C - Face and Neck (exc shave) 3

HYDROGENATED OLIVE OIL 12D - Body and Hand (exc shave) 2

HYDROGENATED OLIVE OIL 12F - Moisturizing 4

HYDROGENATED OLIVE OIL 12G - Night 2

HYDROGENATED OLIVE OIL 12I - Skin Fresheners 3

HYDROGENATED OLIVE OIL 12J - Other Skin Care Preps 2

HYDROGENATED OLIVE OIL UNSAPONIFIABLES 07C - Foundations 1

HYDROGENATED OLIVE OIL UNSAPONIFIABLES 12D - Body and Hand (exc shave) 1

OLEA EUROPAEA (OLIVE) OIL UNSAPONIFIABLES 03D - Eye Lotion 2

OLEA EUROPAEA (OLIVE) OIL UNSAPONIFIABLES 03F - Mascara 4

OLEA EUROPAEA (OLIVE) OIL UNSAPONIFIABLES 03G - Other Eye Makeup Preparations 6

OLEA EUROPAEA (OLIVE) OIL UNSAPONIFIABLES 05A - Hair Conditioner 2

OLEA EUROPAEA (OLIVE) OIL UNSAPONIFIABLES 05C - Hair Straighteners 1

OLEA EUROPAEA (OLIVE) OIL UNSAPONIFIABLES 05F - Shampoos (non-coloring) 2

OLEA EUROPAEA (OLIVE) OIL UNSAPONIFIABLES 05I - Other Hair Preparations 1

OLEA EUROPAEA (OLIVE) OIL UNSAPONIFIABLES 07B - Face Powders 1

OLEA EUROPAEA (OLIVE) OIL UNSAPONIFIABLES 07E - Lipstick 1

OLEA EUROPAEA (OLIVE) OIL UNSAPONIFIABLES 07I - Other Makeup Preparations 2

OLEA EUROPAEA (OLIVE) OIL UNSAPONIFIABLES 10A - Bath Soaps and Detergents 4

OLEA EUROPAEA (OLIVE) OIL UNSAPONIFIABLES 12C - Face and Neck (exc shave) 14

OLEA EUROPAEA (OLIVE) OIL UNSAPONIFIABLES 12D - Body and Hand (exc shave) 2

OLEA EUROPAEA (OLIVE) OIL UNSAPONIFIABLES 12F - Moisturizing 26

OLEA EUROPAEA (OLIVE) OIL UNSAPONIFIABLES 12G - Night 4

OLEA EUROPAEA (OLIVE) OIL UNSAPONIFIABLES 12J - Other Skin Care Preps 3

OLEA EUROPAEA (OLIVE) OIL UNSAPONIFIABLES 13C - Other Suntan Preparations 2

OLIVE OIL FATTY ACIDS, POTASSIUM SALTS 10E - Other Personal Cleanliness Products 1

OLIVE OIL FATTY ACIDS, POTASSIUM SALTS 11E - Shaving Cream 2

SODIUM OLIVATE 01C - Other Baby Products 1

SODIUM OLIVATE 10A - Bath Soaps and Detergents 9

SODIUM OLIVATE 11E - Shaving Cream 2

SODIUM OLIVATE 12J - Other Skin Care Preps 4



ACTINIDIA CHINENSIS (KIWI) SEED OIL 04E - Other Fragrance Preparation 1

ACTINIDIA CHINENSIS (KIWI) SEED OIL 05A - Hair Conditioner 2

ACTINIDIA CHINENSIS (KIWI) SEED OIL 07E - Lipstick 1

ACTINIDIA CHINENSIS (KIWI) SEED OIL 12G - Night 3

ADANSONIA DIGITATA SEED OIL 01A - Baby Shampoos 1

ADANSONIA DIGITATA SEED OIL 01B - Baby Lotions, Oils, Powders, and Creams 1

ADANSONIA DIGITATA SEED OIL 12F - Moisturizing 2

ADANSONIA DIGITATA SEED OIL 12H - Paste Masks (mud packs) 1

ADANSONIA DIGITATA SEED OIL 12J - Other Skin Care Preps 1

ARGANIA SPINOSA KERNEL OIL 02D - Other Bath Preparations 1

ARGANIA SPINOSA KERNEL OIL 03A - Eyebrow Pencil 1

ARGANIA SPINOSA KERNEL OIL 03B - Eyeliner 3

ARGANIA SPINOSA KERNEL OIL 03C - Eye Shadow 2

ARGANIA SPINOSA KERNEL OIL 03D - Eye Lotion 1

ARGANIA SPINOSA KERNEL OIL 03F - Mascara 2

ARGANIA SPINOSA KERNEL OIL 05A - Hair Conditioner 2

ARGANIA SPINOSA KERNEL OIL 05F - Shampoos (non-coloring) 1

ARGANIA SPINOSA KERNEL OIL 05G - Tonics, Dressings, and Other Hair Grooming Aids 2

ARGANIA SPINOSA KERNEL OIL 05I - Other Hair Preparations 3

ARGANIA SPINOSA KERNEL OIL 07A - Blushers (all types) 1

ARGANIA SPINOSA KERNEL OIL 07B - Face Powders 1

ARGANIA SPINOSA KERNEL OIL 07E - Lipstick 9

ARGANIA SPINOSA KERNEL OIL 07I - Other Makeup Preparations 1

ARGANIA SPINOSA KERNEL OIL 08E - Nail Polish and Enamel 1

ARGANIA SPINOSA KERNEL OIL 08G - Other Manicuring Preparations 1

ARGANIA SPINOSA KERNEL OIL 10A - Bath Soaps and Detergents 2

ARGANIA SPINOSA KERNEL OIL 10E - Other Personal Cleanliness Products 1

ARGANIA SPINOSA KERNEL OIL 11A - Aftershave Lotion 1

ARGANIA SPINOSA KERNEL OIL 11E - Shaving Cream 1

ARGANIA SPINOSA KERNEL OIL 11G - Other Shaving Preparation Products 1

ARGANIA SPINOSA KERNEL OIL 12A - Cleansing 2

ARGANIA SPINOSA KERNEL OIL 12C - Face and Neck (exc shave) 8

ARGANIA SPINOSA KERNEL OIL 12D - Body and Hand (exc shave) 12

ARGANIA SPINOSA KERNEL OIL 12F - Moisturizing 12

ARGANIA SPINOSA KERNEL OIL 12G - Night 3

ARGANIA SPINOSA KERNEL OIL 12H - Paste Masks (mud packs) 2

ARGANIA SPINOSA KERNEL OIL 12J - Other Skin Care Preps 3

ARGANIA SPINOSA KERNEL OIL 13A - Suntan Gels, Creams, and Liquids 3

ARGANIA SPINOSA KERNEL OIL 13B - Indoor Tanning Preparations 11

ARGANIA SPINOSA KERNEL OIL 13C - Other Suntan Preparations 6

ASTROCARYUM MURUMURU SEED BUTTER 03B - Eyeliner 3

ASTROCARYUM MURUMURU SEED BUTTER 03D - Eye Lotion 7

ASTROCARYUM MURUMURU SEED BUTTER 03G - Other Eye Makeup Preparations 11

ASTROCARYUM MURUMURU SEED BUTTER 05A - Hair Conditioner 4

ASTROCARYUM MURUMURU SEED BUTTER 05E - Rinses (non-coloring) 1

ASTROCARYUM MURUMURU SEED BUTTER 05F - Shampoos (non-coloring) 3

ASTROCARYUM MURUMURU SEED BUTTER 05G - Tonics, Dressings, and Other Hair Grooming Aids 1

ASTROCARYUM MURUMURU SEED BUTTER 05I - Other Hair Preparations 2

ASTROCARYUM MURUMURU SEED BUTTER 06H - Other Hair Coloring Preparation 3

ASTROCARYUM MURUMURU SEED BUTTER 07B - Face Powders 5

ASTROCARYUM MURUMURU SEED BUTTER 07C - Foundations 23

ASTROCARYUM MURUMURU SEED BUTTER 07E - Lipstick 22

ASTROCARYUM MURUMURU SEED BUTTER 07I - Other Makeup Preparations 6

ASTROCARYUM MURUMURU SEED BUTTER 10A - Bath Soaps and Detergents 1

ASTROCARYUM MURUMURU SEED BUTTER 10E - Other Personal Cleanliness Products 2

ASTROCARYUM MURUMURU SEED BUTTER 11A - Aftershave Lotion 1

ASTROCARYUM MURUMURU SEED BUTTER 12A - Cleansing 4

ASTROCARYUM MURUMURU SEED BUTTER 12C - Face and Neck (exc shave) 5



ASTROCARYUM MURUMURU SEED BUTTER 12D - Body and Hand (exc shave) 21

ASTROCARYUM MURUMURU SEED BUTTER 12F - Moisturizing 57

ASTROCARYUM MURUMURU SEED BUTTER 12G - Night 6

ASTROCARYUM MURUMURU SEED BUTTER 12H - Paste Masks (mud packs) 3

ASTROCARYUM MURUMURU SEED BUTTER 12J - Other Skin Care Preps 1

AVENA SATIVA (OAT) KERNEL OIL 01A - Baby Shampoos 2

AVENA SATIVA (OAT) KERNEL OIL 01B - Baby Lotions, Oils, Powders, and Creams 4

AVENA SATIVA (OAT) KERNEL OIL 02B - Bubble Baths 1

AVENA SATIVA (OAT) KERNEL OIL 07I - Other Makeup Preparations 1

AVENA SATIVA (OAT) KERNEL OIL 10A - Bath Soaps and Detergents 1

AVENA SATIVA (OAT) KERNEL OIL 10E - Other Personal Cleanliness Products 1

AVENA SATIVA (OAT) KERNEL OIL 12A - Cleansing 1

AVENA SATIVA (OAT) KERNEL OIL 12D - Body and Hand (exc shave) 3

AVENA SATIVA (OAT) KERNEL OIL 12F - Moisturizing 27

AVENA SATIVA (OAT) KERNEL OIL 12G - Night 1

AVENA SATIVA (OAT) KERNEL OIL 13C - Other Suntan Preparations 1

BORAGO OFFICINALIS SEED OIL 01B - Baby Lotions, Oils, Powders, and Creams 3

BORAGO OFFICINALIS SEED OIL 02A - Bath Oils, Tablets, and Salts 1

BORAGO OFFICINALIS SEED OIL 03C - Eye Shadow 2

BORAGO OFFICINALIS SEED OIL 03D - Eye Lotion 3

BORAGO OFFICINALIS SEED OIL 03F - Mascara 2

BORAGO OFFICINALIS SEED OIL 04E - Other Fragrance Preparation 1

BORAGO OFFICINALIS SEED OIL 05A - Hair Conditioner 3

BORAGO OFFICINALIS SEED OIL 05B - Hair Spray (aerosol fixatives) 2

BORAGO OFFICINALIS SEED OIL 05F - Shampoos (non-coloring) 2

BORAGO OFFICINALIS SEED OIL 05G - Tonics, Dressings, and Other Hair Grooming Aids 3

BORAGO OFFICINALIS SEED OIL 07A - Blushers (all types) 2

BORAGO OFFICINALIS SEED OIL 07C - Foundations 1

BORAGO OFFICINALIS SEED OIL 07E - Lipstick 1

BORAGO OFFICINALIS SEED OIL 07I - Other Makeup Preparations 1

BORAGO OFFICINALIS SEED OIL 10A - Bath Soaps and Detergents 2

BORAGO OFFICINALIS SEED OIL 10E - Other Personal Cleanliness Products 2

BORAGO OFFICINALIS SEED OIL 12A - Cleansing 7

BORAGO OFFICINALIS SEED OIL 12C - Face and Neck (exc shave) 30

BORAGO OFFICINALIS SEED OIL 12D - Body and Hand (exc shave) 23

BORAGO OFFICINALIS SEED OIL 12F - Moisturizing 54

BORAGO OFFICINALIS SEED OIL 12G - Night 8

BORAGO OFFICINALIS SEED OIL 12H - Paste Masks (mud packs) 3

BORAGO OFFICINALIS SEED OIL 12J - Other Skin Care Preps 17

BORAGO OFFICINALIS SEED OIL 13B - Indoor Tanning Preparations 7

CAMELINA SATIVA SEED OIL 05A - Hair Conditioner 8

CAMELINA SATIVA SEED OIL 05F - Shampoos (non-coloring) 7

CAMELINA SATIVA SEED OIL 05G - Tonics, Dressings, and Other Hair Grooming Aids 1

CAMELINA SATIVA SEED OIL 05I - Other Hair Preparations 13

CAMELINA SATIVA SEED OIL 07E - Lipstick 34

CAMELINA SATIVA SEED OIL 12C - Face and Neck (exc shave) 3

CAMELINA SATIVA SEED OIL 12D - Body and Hand (exc shave) 4

CAMELINA SATIVA SEED OIL 12F - Moisturizing 6

CAMELLIA OLEIFERA SEED OIL 05F - Shampoos (non-coloring) 1

CAMELLIA OLEIFERA SEED OIL 05G - Tonics, Dressings, and Other Hair Grooming Aids 1

CAMELLIA OLEIFERA SEED OIL 07E - Lipstick 3

CAMELLIA OLEIFERA SEED OIL 12A - Cleansing 1

CAMELLIA OLEIFERA SEED OIL 12C - Face and Neck (exc shave) 2

CAMELLIA OLEIFERA SEED OIL 12D - Body and Hand (exc shave) 7

CAMELLIA OLEIFERA SEED OIL 12F - Moisturizing 8

CAMELLIA OLEIFERA SEED OIL 12G - Night 2



HYDROGENATED CAMELLIA OLEIFERA SEED OIL 12F - Moisturizing 1

CAMELLIA SINENSIS SEED OIL 05A - Hair Conditioner 1

CAMELLIA SINENSIS SEED OIL 05F - Shampoos (non-coloring) 1

CAMELLIA SINENSIS SEED OIL 07B - Face Powders 1

CAMELLIA SINENSIS SEED OIL 07E - Lipstick 1

CAMELLIA SINENSIS SEED OIL 07I - Other Makeup Preparations 2

CAMELLIA SINENSIS SEED OIL 10A - Bath Soaps and Detergents 2

CAMELLIA SINENSIS SEED OIL 12F - Moisturizing 4

CARYOCAR BRASILIENSE FRUIT OIL 03D - Eye Lotion 12

CARYOCAR BRASILIENSE FRUIT OIL 05A - Hair Conditioner 1

CARYOCAR BRASILIENSE FRUIT OIL 07E - Lipstick 12

CARYOCAR BRASILIENSE FRUIT OIL 12C - Face and Neck (exc shave) 2

CARYOCAR BRASILIENSE FRUIT OIL 12D - Body and Hand (exc shave) 2

CARYOCAR BRASILIENSE FRUIT OIL 12F - Moisturizing 1

CARYOCAR BRASILIENSE FRUIT OIL 12H - Paste Masks (mud packs) 1

QUINOA OIL 05G - Tonics, Dressings, and Other Hair Grooming Aids 1

CITRULLUS LANATUS (WATERMELON) SEED OIL 07A - Blushers (all types) 1

CITRULLUS VULGARIS (WATERMELON) SEED OIL 07I - Other Makeup Preparations 1

CITRUS PARADISI (GRAPEFRUIT) SEED OIL 10A - Bath Soaps and Detergents 1

CITRUS PARADISI (GRAPEFRUIT) SEED OIL 12C - Face and Neck (exc shave) 1

CITRUS PARADISI (GRAPEFRUIT) SEED OIL 12D - Body and Hand (exc shave) 1

CITRUS PARADISI (GRAPEFRUIT) SEED OIL 12F - Moisturizing 3

CITRUS MEDICA LIMONUM (LEMON) SEED OIL 10A - Bath Soaps and Detergents 1

CITRUS MEDICA LIMONUM (LEMON) SEED OIL 12F - Moisturizing 1

CITRUS MEDICA LIMONUM (LEMON) SEED OIL 12H - Paste Masks (mud packs) 1

CITRUS MEDICA LIMONUM (LEMON) SEED OIL 12J - Other Skin Care Preps 2

CUCUMIS SATIVUS (CUCUMBER) OIL 03D - Eye Lotion 1

CUCUMIS SATIVUS (CUCUMBER) OIL 05F - Shampoos (non-coloring) 1

CUCUMIS SATIVUS (CUCUMBER) OIL 12C - Face and Neck (exc shave) 1

CUCUMIS SATIVUS (CUCUMBER) OIL 12F - Moisturizing 1

CUCUMIS SATIVUS (CUCUMBER) OIL 12J - Other Skin Care Preps 2

CUCURBITA PEPO (PUMPKIN) SEED OIL 03D - Eye Lotion 1

CUCURBITA PEPO (PUMPKIN) SEED OIL 04C - Powders (dusting and talcum, excluding aftershave talc) 1

CUCURBITA PEPO (PUMPKIN) SEED OIL 05G - Tonics, Dressings, and Other Hair Grooming Aids 1

CUCURBITA PEPO (PUMPKIN) SEED OIL 12A - Cleansing 1

CUCURBITA PEPO (PUMPKIN) SEED OIL 12C - Face and Neck (exc shave) 4

CUCURBITA PEPO (PUMPKIN) SEED OIL 12D - Body and Hand (exc shave) 3

CUCURBITA PEPO (PUMPKIN) SEED OIL 12F - Moisturizing 5

CUCURBITA PEPO (PUMPKIN) SEED OIL 12G - Night 1

CUCURBITA PEPO (PUMPKIN) SEED OIL 13A - Suntan Gels, Creams, and Liquids 1

EUTERPE OLERACEA FRUIT OIL 03C - Eye Shadow 1

EUTERPE OLERACEA FRUIT OIL 03D - Eye Lotion 1

EUTERPE OLERACEA FRUIT OIL 05A - Hair Conditioner 2

EUTERPE OLERACEA FRUIT OIL 05B - Hair Spray (aerosol fixatives) 1

EUTERPE OLERACEA FRUIT OIL 05F - Shampoos (non-coloring) 4



EUTERPE OLERACEA FRUIT OIL 05G - Tonics, Dressings, and Other Hair Grooming Aids 5

EUTERPE OLERACEA FRUIT OIL 05I - Other Hair Preparations 3

EUTERPE OLERACEA FRUIT OIL 07E - Lipstick 1

EUTERPE OLERACEA FRUIT OIL 10A - Bath Soaps and Detergents 2

EUTERPE OLERACEA FRUIT OIL 10E - Other Personal Cleanliness Products 1

EUTERPE OLERACEA FRUIT OIL 12A - Cleansing 1

EUTERPE OLERACEA FRUIT OIL 12C - Face and Neck (exc shave) 2

EUTERPE OLERACEA FRUIT OIL 12F - Moisturizing 3

EUTERPE OLERACEA FRUIT OIL 12G - Night 2

IRVINGIA GABONENSIS KERNEL BUTTER 03D - Eye Lotion 2

IRVINGIA GABONENSIS KERNEL BUTTER 05G - Tonics, Dressings, and Other Hair Grooming Aids 1

IRVINGIA GABONENSIS KERNEL BUTTER 07E - Lipstick 64

IRVINGIA GABONENSIS KERNEL BUTTER 07I - Other Makeup Preparations 1

IRVINGIA GABONENSIS KERNEL BUTTER 12C - Face and Neck (exc shave) 11

IRVINGIA GABONENSIS KERNEL BUTTER 12D - Body and Hand (exc shave) 8

IRVINGIA GABONENSIS KERNEL BUTTER 12F - Moisturizing 15

IRVINGIA GABONENSIS KERNEL BUTTER 12G - Night 1

IRVINGIA GABONENSIS KERNEL BUTTER 12J - Other Skin Care Preps 1

IRVINGIA GABONENSIS KERNEL BUTTER 13A - Suntan Gels, Creams, and Liquids 2

IRVINGIA GABONENSIS KERNEL BUTTER 13B - Indoor Tanning Preparations 3

LIMNANTHES ALBA (MEADOWFOAM) SEED OIL 01B - Baby Lotions, Oils, Powders, and Creams 1

LIMNANTHES ALBA (MEADOWFOAM) SEED OIL 02A - Bath Oils, Tablets, and Salts 2

LIMNANTHES ALBA (MEADOWFOAM) SEED OIL 03B - Eyeliner 13

LIMNANTHES ALBA (MEADOWFOAM) SEED OIL 03D - Eye Lotion 4

LIMNANTHES ALBA (MEADOWFOAM) SEED OIL 03F - Mascara 12

LIMNANTHES ALBA (MEADOWFOAM) SEED OIL 03G - Other Eye Makeup Preparations 1

LIMNANTHES ALBA (MEADOWFOAM) SEED OIL 05A - Hair Conditioner 17

LIMNANTHES ALBA (MEADOWFOAM) SEED OIL 05F - Shampoos (non-coloring) 7

LIMNANTHES ALBA (MEADOWFOAM) SEED OIL 05G - Tonics, Dressings, and Other Hair Grooming Aids 17

LIMNANTHES ALBA (MEADOWFOAM) SEED OIL 05I - Other Hair Preparations 6

LIMNANTHES ALBA (MEADOWFOAM) SEED OIL 06A - Hair Dyes and Colors (all types requiring caution statements and patch tests) 43

LIMNANTHES ALBA (MEADOWFOAM) SEED OIL 06D - Hair Shampoos (coloring) 2

LIMNANTHES ALBA (MEADOWFOAM) SEED OIL 06H - Other Hair Coloring Preparation 1

LIMNANTHES ALBA (MEADOWFOAM) SEED OIL 07C - Foundations 6

LIMNANTHES ALBA (MEADOWFOAM) SEED OIL 07E - Lipstick 67

LIMNANTHES ALBA (MEADOWFOAM) SEED OIL 07I - Other Makeup Preparations 7

LIMNANTHES ALBA (MEADOWFOAM) SEED OIL 10A - Bath Soaps and Detergents 3

LIMNANTHES ALBA (MEADOWFOAM) SEED OIL 10E - Other Personal Cleanliness Products 1

LIMNANTHES ALBA (MEADOWFOAM) SEED OIL 11E - Shaving Cream 2

LIMNANTHES ALBA (MEADOWFOAM) SEED OIL 11G - Other Shaving Preparation Products 1

LIMNANTHES ALBA (MEADOWFOAM) SEED OIL 12A - Cleansing 9

LIMNANTHES ALBA (MEADOWFOAM) SEED OIL 12C - Face and Neck (exc shave) 24

LIMNANTHES ALBA (MEADOWFOAM) SEED OIL 12D - Body and Hand (exc shave) 18

LIMNANTHES ALBA (MEADOWFOAM) SEED OIL 12E - Foot Powders and Sprays 1

LIMNANTHES ALBA (MEADOWFOAM) SEED OIL 12F - Moisturizing 28

LIMNANTHES ALBA (MEADOWFOAM) SEED OIL 12G - Night 9

LIMNANTHES ALBA (MEADOWFOAM) SEED OIL 12H - Paste Masks (mud packs) 3

LIMNANTHES ALBA (MEADOWFOAM) SEED OIL 12I - Skin Fresheners 1

LIMNANTHES ALBA (MEADOWFOAM) SEED OIL 12J - Other Skin Care Preps 9

LIMNANTHES ALBA (MEADOWFOAM) SEED OIL 13B - Indoor Tanning Preparations 1

LINUM USITATISSIMUM (LINSEED) SEED OIL 01B - Baby Lotions, Oils, Powders, and Creams 2

LINUM USITATISSIMUM (LINSEED) SEED OIL 02A - Bath Oils, Tablets, and Salts 1

LINUM USITATISSIMUM (LINSEED) SEED OIL 02D - Other Bath Preparations 1

LINUM USITATISSIMUM (LINSEED) SEED OIL 03D - Eye Lotion 2

LINUM USITATISSIMUM (LINSEED) SEED OIL 03G - Other Eye Makeup Preparations 1

LINUM USITATISSIMUM (LINSEED) SEED OIL 05A - Hair Conditioner 13

LINUM USITATISSIMUM (LINSEED) SEED OIL 05B - Hair Spray (aerosol fixatives) 3

LINUM USITATISSIMUM (LINSEED) SEED OIL 05F - Shampoos (non-coloring) 10

LINUM USITATISSIMUM (LINSEED) SEED OIL 05G - Tonics, Dressings, and Other Hair Grooming Aids 14



LINUM USITATISSIMUM (LINSEED) SEED OIL 05I - Other Hair Preparations 2

LINUM USITATISSIMUM (LINSEED) SEED OIL 07I - Other Makeup Preparations 1

LINUM USITATISSIMUM (LINSEED) SEED OIL 08E - Nail Polish and Enamel 2

LINUM USITATISSIMUM (LINSEED) SEED OIL 10A - Bath Soaps and Detergents 4

LINUM USITATISSIMUM (LINSEED) SEED OIL 10E - Other Personal Cleanliness Products 1

LINUM USITATISSIMUM (LINSEED) SEED OIL 11E - Shaving Cream 2

LINUM USITATISSIMUM (LINSEED) SEED OIL 12A - Cleansing 18

LINUM USITATISSIMUM (LINSEED) SEED OIL 12C - Face and Neck (exc shave) 7

LINUM USITATISSIMUM (LINSEED) SEED OIL 12D - Body and Hand (exc shave) 5

LINUM USITATISSIMUM (LINSEED) SEED OIL 12F - Moisturizing 8

LINUM USITATISSIMUM (LINSEED) SEED OIL 12G - Night 2

LINUM USITATISSIMUM (LINSEED) SEED OIL 12I - Skin Fresheners 1

LINUM USITATISSIMUM (LINSEED) SEED OIL 12J - Other Skin Care Preps 2

LINSEED ACID 01B - Baby Lotions, Oils, Powders, and Creams 1

LINSEED ACID 12D - Body and Hand (exc shave) 1

LINSEED ACID 12J - Other Skin Care Preps 1

MANGIFERA INDICA (MANGO) SEED OIL 03B - Eyeliner 13

MANGIFERA INDICA (MANGO) SEED OIL 04E - Other Fragrance Preparation 1

MANGIFERA INDICA (MANGO) SEED OIL 05A - Hair Conditioner 2

MANGIFERA INDICA (MANGO) SEED OIL 05F - Shampoos (non-coloring) 3

MANGIFERA INDICA (MANGO) SEED OIL 05G - Tonics, Dressings, and Other Hair Grooming Aids 1

MANGIFERA INDICA (MANGO) SEED OIL 05I - Other Hair Preparations 6

MANGIFERA INDICA (MANGO) SEED OIL 07E - Lipstick 7

MANGIFERA INDICA (MANGO) SEED OIL 07I - Other Makeup Preparations 7

MANGIFERA INDICA (MANGO) SEED OIL 10E - Other Personal Cleanliness Products 2

MANGIFERA INDICA (MANGO) SEED OIL 12C - Face and Neck (exc shave) 8

MANGIFERA INDICA (MANGO) SEED OIL 12D - Body and Hand (exc shave) 7

MANGIFERA INDICA (MANGO) SEED OIL 12F - Moisturizing 9

MANGIFERA INDICA (MANGO) SEED OIL 12G - Night 1

MANGIFERA INDICA (MANGO) SEED OIL 12H - Paste Masks (mud packs) 1

MANGIFERA INDICA (MANGO) SEED OIL 12J - Other Skin Care Preps 4

MANGIFERA INDICA (MANGO) SEED BUTTER 01B - Baby Lotions, Oils, Powders, and Creams 3

MANGIFERA INDICA (MANGO) SEED BUTTER 02B - Bubble Baths 1

MANGIFERA INDICA (MANGO) SEED BUTTER 02D - Other Bath Preparations 3

MANGIFERA INDICA (MANGO) SEED BUTTER 03C - Eye Shadow 4

MANGIFERA INDICA (MANGO) SEED BUTTER 03D - Eye Lotion 2

MANGIFERA INDICA (MANGO) SEED BUTTER 04B - Perfumes 2

MANGIFERA INDICA (MANGO) SEED BUTTER 05A - Hair Conditioner 2

MANGIFERA INDICA (MANGO) SEED BUTTER 05F - Shampoos (non-coloring) 3

MANGIFERA INDICA (MANGO) SEED BUTTER 05G - Tonics, Dressings, and Other Hair Grooming Aids 4

MANGIFERA INDICA (MANGO) SEED BUTTER 05I - Other Hair Preparations 3

MANGIFERA INDICA (MANGO) SEED BUTTER 06A - Hair Dyes and Colors (all types requiring caution statements and patch tests) 13

MANGIFERA INDICA (MANGO) SEED BUTTER 06H - Other Hair Coloring Preparation 3

MANGIFERA INDICA (MANGO) SEED BUTTER 07A - Blushers (all types) 3

MANGIFERA INDICA (MANGO) SEED BUTTER 07B - Face Powders 5

MANGIFERA INDICA (MANGO) SEED BUTTER 07C - Foundations 1

MANGIFERA INDICA (MANGO) SEED BUTTER 07E - Lipstick 25

MANGIFERA INDICA (MANGO) SEED BUTTER 07H - Makeup Fixatives 3

MANGIFERA INDICA (MANGO) SEED BUTTER 07I - Other Makeup Preparations 7

MANGIFERA INDICA (MANGO) SEED BUTTER 10A - Bath Soaps and Detergents 5

MANGIFERA INDICA (MANGO) SEED BUTTER 10E - Other Personal Cleanliness Products 5

MANGIFERA INDICA (MANGO) SEED BUTTER 12A - Cleansing 3

MANGIFERA INDICA (MANGO) SEED BUTTER 12C - Face and Neck (exc shave) 4

MANGIFERA INDICA (MANGO) SEED BUTTER 12D - Body and Hand (exc shave) 15

MANGIFERA INDICA (MANGO) SEED BUTTER 12F - Moisturizing 39

MANGIFERA INDICA (MANGO) SEED BUTTER 12G - Night 2

MANGIFERA INDICA (MANGO) SEED BUTTER 12H - Paste Masks (mud packs) 3

MANGIFERA INDICA (MANGO) SEED BUTTER 12J - Other Skin Care Preps 10

MANGIFERA INDICA (MANGO) SEED BUTTER 13B - Indoor Tanning Preparations 2



SODIUM MANGOSEEDATE 10A - Bath Soaps and Detergents 1

#REF! 03F - Mascara 4

MORINGA PTERYGOSPERMA SEED OIL 07E - Lipstick 1

MORINGA PTERYGOSPERMA SEED OIL 07I - Other Makeup Preparations 1

MORINGA PTERYGOSPERMA SEED OIL 12A - Cleansing 2

MORINGA PTERYGOSPERMA SEED OIL 12C - Face and Neck (exc shave) 2

MORINGA PTERYGOSPERMA SEED OIL 12D - Body and Hand (exc shave) 2

MORINGA PTERYGOSPERMA SEED OIL 12F - Moisturizing 2

MORINGA PTERYGOSPERMA SEED OIL 12J - Other Skin Care Preps 1

OENOTHERA BIENNIS (EVENING PRIMROSE) OIL 01B - Baby Lotions, Oils, Powders, and Creams 3

OENOTHERA BIENNIS (EVENING PRIMROSE) OIL 02A - Bath Oils, Tablets, and Salts 1

OENOTHERA BIENNIS (EVENING PRIMROSE) OIL 02B - Bubble Baths 1

OENOTHERA BIENNIS (EVENING PRIMROSE) OIL 03D - Eye Lotion 4

OENOTHERA BIENNIS (EVENING PRIMROSE) OIL 05A - Hair Conditioner 16

OENOTHERA BIENNIS (EVENING PRIMROSE) OIL 05B - Hair Spray (aerosol fixatives) 2

OENOTHERA BIENNIS (EVENING PRIMROSE) OIL 05F - Shampoos (non-coloring) 5

OENOTHERA BIENNIS (EVENING PRIMROSE) OIL 05G - Tonics, Dressings, and Other Hair Grooming Aids 6

OENOTHERA BIENNIS (EVENING PRIMROSE) OIL 05I - Other Hair Preparations 8

OENOTHERA BIENNIS (EVENING PRIMROSE) OIL 07A - Blushers (all types) 1

OENOTHERA BIENNIS (EVENING PRIMROSE) OIL 07C - Foundations 2

OENOTHERA BIENNIS (EVENING PRIMROSE) OIL 07E - Lipstick 14

OENOTHERA BIENNIS (EVENING PRIMROSE) OIL 07I - Other Makeup Preparations 2

OENOTHERA BIENNIS (EVENING PRIMROSE) OIL 08B - Cuticle Softeners 1

OENOTHERA BIENNIS (EVENING PRIMROSE) OIL 08E - Nail Polish and Enamel 2

OENOTHERA BIENNIS (EVENING PRIMROSE) OIL 08G - Other Manicuring Preparations 1

OENOTHERA BIENNIS (EVENING PRIMROSE) OIL 10A - Bath Soaps and Detergents 4

OENOTHERA BIENNIS (EVENING PRIMROSE) OIL 11E - Shaving Cream 1

OENOTHERA BIENNIS (EVENING PRIMROSE) OIL 12A - Cleansing 6

OENOTHERA BIENNIS (EVENING PRIMROSE) OIL 12C - Face and Neck (exc shave) 10

OENOTHERA BIENNIS (EVENING PRIMROSE) OIL 12D - Body and Hand (exc shave) 15

OENOTHERA BIENNIS (EVENING PRIMROSE) OIL 12F - Moisturizing 24

OENOTHERA BIENNIS (EVENING PRIMROSE) OIL 12G - Night 8

OENOTHERA BIENNIS (EVENING PRIMROSE) OIL 12H - Paste Masks (mud packs) 3

OENOTHERA BIENNIS (EVENING PRIMROSE) OIL 12J - Other Skin Care Preps 9

OENOTHERA BIENNIS (EVENING PRIMROSE) OIL 13B - Indoor Tanning Preparations 1

HYDROGENATED EVENING PRIMROSE OIL 03B - Eyeliner 1

HYDROGENATED EVENING PRIMROSE OIL 12C - Face and Neck (exc shave) 2

HYDROGENATED EVENING PRIMROSE OIL 12D - Body and Hand (exc shave) 5

HYDROGENATED EVENING PRIMROSE OIL 12F - Moisturizing 6

ORBIGNYA COHUNE SEED OIL 05A - Hair Conditioner 1

ORBIGNYA OLEIFERA SEED OIL 02D - Other Bath Preparations 2

ORBIGNYA OLEIFERA SEED OIL 03C - Eye Shadow 1

ORBIGNYA OLEIFERA SEED OIL 03D - Eye Lotion 1

ORBIGNYA OLEIFERA SEED OIL 03G - Other Eye Makeup Preparations 5

ORBIGNYA OLEIFERA SEED OIL 05A - Hair Conditioner 16

ORBIGNYA OLEIFERA SEED OIL 05B - Hair Spray (aerosol fixatives) 5

ORBIGNYA OLEIFERA SEED OIL 05F - Shampoos (non-coloring) 7

ORBIGNYA OLEIFERA SEED OIL 05G - Tonics, Dressings, and Other Hair Grooming Aids 10

ORBIGNYA OLEIFERA SEED OIL 05I - Other Hair Preparations 5

ORBIGNYA OLEIFERA SEED OIL 06C - Hair Rinses (coloring) 5

ORBIGNYA OLEIFERA SEED OIL 06H - Other Hair Coloring Preparation 3

ORBIGNYA OLEIFERA SEED OIL 07E - Lipstick 57

ORBIGNYA OLEIFERA SEED OIL 07I - Other Makeup Preparations 4



ORBIGNYA OLEIFERA SEED OIL 10A - Bath Soaps and Detergents 3

ORBIGNYA OLEIFERA SEED OIL 10E - Other Personal Cleanliness Products 2

ORBIGNYA OLEIFERA SEED OIL 11G - Other Shaving Preparation Products 1

ORBIGNYA OLEIFERA SEED OIL 12A - Cleansing 4

ORBIGNYA OLEIFERA SEED OIL 12C - Face and Neck (exc shave) 3

ORBIGNYA OLEIFERA SEED OIL 12D - Body and Hand (exc shave) 9

ORBIGNYA OLEIFERA SEED OIL 12F - Moisturizing 12

ORBIGNYA OLEIFERA SEED OIL 12G - Night 3

ORBIGNYA OLEIFERA SEED OIL 12J - Other Skin Care Preps 3

PERILLA OCYMOIDES SEED OIL 03D - Eye Lotion 2

PERILLA OCYMOIDES SEED OIL 05A - Hair Conditioner 2

PERILLA OCYMOIDES SEED OIL 07I - Other Makeup Preparations 1

PERILLA OCYMOIDES SEED OIL 12D - Body and Hand (exc shave) 2

HYDROGENATED AVOCADO OIL 05A - Hair Conditioner 1

HYDROGENATED AVOCADO OIL 05F - Shampoos (non-coloring) 1

HYDROGENATED AVOCADO OIL 05G - Tonics, Dressings, and Other Hair Grooming Aids 1

HYDROGENATED AVOCADO OIL 07E - Lipstick 2

HYDROGENATED AVOCADO OIL 12F - Moisturizing 6

PERSEA GRATISSIMA (AVOCADO) BUTTER 07E - Lipstick 11

PERSEA GRATISSIMA (AVOCADO) BUTTER 12F - Moisturizing 4

PERSEA GRATISSIMA (AVOCADO) OIL UNSAPONIFIABLES 01B - Baby Lotions, Oils, Powders, and Creams 1

PERSEA GRATISSIMA (AVOCADO) OIL UNSAPONIFIABLES 02D - Other Bath Preparations 4

PERSEA GRATISSIMA (AVOCADO) OIL UNSAPONIFIABLES 03B - Eyeliner 1

PERSEA GRATISSIMA (AVOCADO) OIL UNSAPONIFIABLES 03C - Eye Shadow 4

PERSEA GRATISSIMA (AVOCADO) OIL UNSAPONIFIABLES 03D - Eye Lotion 2

PERSEA GRATISSIMA (AVOCADO) OIL UNSAPONIFIABLES 03G - Other Eye Makeup Preparations 2

PERSEA GRATISSIMA (AVOCADO) OIL UNSAPONIFIABLES 04E - Other Fragrance Preparation 4

PERSEA GRATISSIMA (AVOCADO) OIL UNSAPONIFIABLES 05G - Tonics, Dressings, and Other Hair Grooming Aids 2

PERSEA GRATISSIMA (AVOCADO) OIL UNSAPONIFIABLES 07E - Lipstick 2

PERSEA GRATISSIMA (AVOCADO) OIL UNSAPONIFIABLES 07I - Other Makeup Preparations 2

PERSEA GRATISSIMA (AVOCADO) OIL UNSAPONIFIABLES 08C - Nail Creams and Lotions 2

PERSEA GRATISSIMA (AVOCADO) OIL UNSAPONIFIABLES 08G - Other Manicuring Preparations 1

PERSEA GRATISSIMA (AVOCADO) OIL UNSAPONIFIABLES 12A - Cleansing 2

PERSEA GRATISSIMA (AVOCADO) OIL UNSAPONIFIABLES 12C - Face and Neck (exc shave) 4

PERSEA GRATISSIMA (AVOCADO) OIL UNSAPONIFIABLES 12D - Body and Hand (exc shave) 6

PERSEA GRATISSIMA (AVOCADO) OIL UNSAPONIFIABLES 12F - Moisturizing 16

PERSEA GRATISSIMA (AVOCADO) OIL UNSAPONIFIABLES 12G - Night 2

PERSEA GRATISSIMA (AVOCADO) OIL UNSAPONIFIABLES 12J - Other Skin Care Preps 5

PERSEA GRATISSIMA (AVOCADO) OIL UNSAPONIFIABLES 13C - Other Suntan Preparations 1

SODIUM AVOCADOATE 10A - Bath Soaps and Detergents 1

PLUKENETIA VOLUBILIS SEED OIL 03G - Other Eye Makeup Preparations 1

PLUKENETIA VOLUBILIS SEED OIL 07E - Lipstick 3

PLUKENETIA VOLUBILIS SEED OIL 12C - Face and Neck (exc shave) 4

PLUKENETIA VOLUBILIS SEED OIL 12F - Moisturizing 2

PLUKENETIA VOLUBILIS SEED OIL 12G - Night 2

PLUKENETIA VOLUBILIS SEED OIL 12H - Paste Masks (mud packs) 1

PRUNUS ARMENIACA (APRICOT) KERNEL OIL 01B - Baby Lotions, Oils, Powders, and Creams 5

PRUNUS ARMENIACA (APRICOT) KERNEL OIL 01C - Other Baby Products 2

PRUNUS ARMENIACA (APRICOT) KERNEL OIL 02A - Bath Oils, Tablets, and Salts 5

PRUNUS ARMENIACA (APRICOT) KERNEL OIL 02D - Other Bath Preparations 3

PRUNUS ARMENIACA (APRICOT) KERNEL OIL 03A - Eyebrow Pencil 1



PRUNUS ARMENIACA (APRICOT) KERNEL OIL 03B - Eyeliner 1

PRUNUS ARMENIACA (APRICOT) KERNEL OIL 03D - Eye Lotion 8

PRUNUS ARMENIACA (APRICOT) KERNEL OIL 03E - Eye Makeup Remover 2

PRUNUS ARMENIACA (APRICOT) KERNEL OIL 03F - Mascara 4

PRUNUS ARMENIACA (APRICOT) KERNEL OIL 03G - Other Eye Makeup Preparations 9

PRUNUS ARMENIACA (APRICOT) KERNEL OIL 04E - Other Fragrance Preparation 5

PRUNUS ARMENIACA (APRICOT) KERNEL OIL 05A - Hair Conditioner 33

PRUNUS ARMENIACA (APRICOT) KERNEL OIL 05E - Rinses (non-coloring) 1

PRUNUS ARMENIACA (APRICOT) KERNEL OIL 05F - Shampoos (non-coloring) 22

PRUNUS ARMENIACA (APRICOT) KERNEL OIL 05G - Tonics, Dressings, and Other Hair Grooming Aids 3

PRUNUS ARMENIACA (APRICOT) KERNEL OIL 05I - Other Hair Preparations 19

PRUNUS ARMENIACA (APRICOT) KERNEL OIL 06A - Hair Dyes and Colors (all types requiring caution statements and patch tests) 5

PRUNUS ARMENIACA (APRICOT) KERNEL OIL 06D - Hair Shampoos (coloring) 3

PRUNUS ARMENIACA (APRICOT) KERNEL OIL 06G - Hair Bleaches 2

PRUNUS ARMENIACA (APRICOT) KERNEL OIL 07B - Face Powders 1

PRUNUS ARMENIACA (APRICOT) KERNEL OIL 07C - Foundations 4

PRUNUS ARMENIACA (APRICOT) KERNEL OIL 07E - Lipstick 38

PRUNUS ARMENIACA (APRICOT) KERNEL OIL 07I - Other Makeup Preparations 10

PRUNUS ARMENIACA (APRICOT) KERNEL OIL 08A - Basecoats and Undercoats 1

PRUNUS ARMENIACA (APRICOT) KERNEL OIL 08B - Cuticle Softeners 4

PRUNUS ARMENIACA (APRICOT) KERNEL OIL 08C - Nail Creams and Lotions 2

PRUNUS ARMENIACA (APRICOT) KERNEL OIL 08E - Nail Polish and Enamel 1

PRUNUS ARMENIACA (APRICOT) KERNEL OIL 08G - Other Manicuring Preparations 2

PRUNUS ARMENIACA (APRICOT) KERNEL OIL 10A - Bath Soaps and Detergents 11

PRUNUS ARMENIACA (APRICOT) KERNEL OIL 10B - Deodorants (underarm) 1

PRUNUS ARMENIACA (APRICOT) KERNEL OIL 10E - Other Personal Cleanliness Products 12

PRUNUS ARMENIACA (APRICOT) KERNEL OIL 11A - Aftershave Lotion 2

PRUNUS ARMENIACA (APRICOT) KERNEL OIL 11E - Shaving Cream 1

PRUNUS ARMENIACA (APRICOT) KERNEL OIL 11G - Other Shaving Preparation Products 3

PRUNUS ARMENIACA (APRICOT) KERNEL OIL 12A - Cleansing 31

PRUNUS ARMENIACA (APRICOT) KERNEL OIL 12B - Depilatories 2

PRUNUS ARMENIACA (APRICOT) KERNEL OIL 12C - Face and Neck (exc shave) 47

PRUNUS ARMENIACA (APRICOT) KERNEL OIL 12D - Body and Hand (exc shave) 87

PRUNUS ARMENIACA (APRICOT) KERNEL OIL 12F - Moisturizing 124

PRUNUS ARMENIACA (APRICOT) KERNEL OIL 12G - Night 13

PRUNUS ARMENIACA (APRICOT) KERNEL OIL 12H - Paste Masks (mud packs) 3

PRUNUS ARMENIACA (APRICOT) KERNEL OIL 12I - Skin Fresheners 4

PRUNUS ARMENIACA (APRICOT) KERNEL OIL 12J - Other Skin Care Preps 46

PRUNUS ARMENIACA (APRICOT) KERNEL OIL 13B - Indoor Tanning Preparations 5

HYDROGENATED APRICOT KERNEL OIL 12D - Body and Hand (exc shave) 1

HYDROGENATED APRICOT KERNEL OIL 12F - Moisturizing 1

PRUNUS AVIUM (SWEET CHERRY) SEED OIL 10A - Bath Soaps and Detergents 2

PRUNUS PERSICA (PEACH) KERNEL OIL 02A - Bath Oils, Tablets, and Salts 1

PRUNUS PERSICA (PEACH) KERNEL OIL 05F - Shampoos (non-coloring) 2

PRUNUS PERSICA (PEACH) KERNEL OIL 05I - Other Hair Preparations 2

PRUNUS PERSICA (PEACH) KERNEL OIL 07I - Other Makeup Preparations 1

PRUNUS PERSICA (PEACH) KERNEL OIL 10E - Other Personal Cleanliness Products 1

PRUNUS PERSICA (PEACH) KERNEL OIL 12A - Cleansing 2

PRUNUS PERSICA (PEACH) KERNEL OIL 12C - Face and Neck (exc shave) 1

PRUNUS PERSICA (PEACH) KERNEL OIL 12D - Body and Hand (exc shave) 4

PRUNUS PERSICA (PEACH) KERNEL OIL 12F - Moisturizing 2

PRUNUS PERSICA (PEACH) KERNEL OIL 12J - Other Skin Care Preps 6

PYRUS MALUS (APPLE ) SEED OIL 07E - Lipstick 7

PYRUS MALUS (APPLE ) SEED OIL 12F - Moisturizing 1

RIBES NIGRUM (BLACK CURRANT) SEED OIL 03G - Other Eye Makeup Preparations 2



RIBES NIGRUM (BLACK CURRANT) SEED OIL 05A - Hair Conditioner 1

RIBES NIGRUM (BLACK CURRANT) SEED OIL 05F - Shampoos (non-coloring) 2

RIBES NIGRUM (BLACK CURRANT) SEED OIL 05I - Other Hair Preparations 2

RIBES NIGRUM (BLACK CURRANT) SEED OIL 07C - Foundations 1

RIBES NIGRUM (BLACK CURRANT) SEED OIL 07E - Lipstick 7

RIBES NIGRUM (BLACK CURRANT) SEED OIL 07I - Other Makeup Preparations 2

RIBES NIGRUM (BLACK CURRANT) SEED OIL 08A - Basecoats and Undercoats 1

RIBES NIGRUM (BLACK CURRANT) SEED OIL 08B - Cuticle Softeners 1

RIBES NIGRUM (BLACK CURRANT) SEED OIL 08E - Nail Polish and Enamel 2

RIBES NIGRUM (BLACK CURRANT) SEED OIL 08G - Other Manicuring Preparations 1

RIBES NIGRUM (BLACK CURRANT) SEED OIL 10A - Bath Soaps and Detergents 1

RIBES NIGRUM (BLACK CURRANT) SEED OIL 10E - Other Personal Cleanliness Products 1

RIBES NIGRUM (BLACK CURRANT) SEED OIL 12A - Cleansing 2

RIBES NIGRUM (BLACK CURRANT) SEED OIL 12C - Face and Neck (exc shave) 7

RIBES NIGRUM (BLACK CURRANT) SEED OIL 12D - Body and Hand (exc shave) 1

RIBES NIGRUM (BLACK CURRANT) SEED OIL 12F - Moisturizing 14

RIBES NIGRUM (BLACK CURRANT) SEED OIL 12G - Night 2

RIBES NIGRUM (BLACK CURRANT) SEED OIL 12H - Paste Masks (mud packs) 1

RIBES NIGRUM (BLACK CURRANT) SEED OIL 12J - Other Skin Care Preps 2

RUBUS IDAEUS (RASPBERRY) SEED OIL 02D - Other Bath Preparations 1

RUBUS IDAEUS (RASPBERRY) SEED OIL 07E - Lipstick 1

RUBUS IDAEUS (RASPBERRY) SEED OIL 07I - Other Makeup Preparations 2

RUBUS IDAEUS (RASPBERRY) SEED OIL 12A - Cleansing 1

RUBUS IDAEUS (RASPBERRY) SEED OIL 12C - Face and Neck (exc shave) 2

RUBUS IDAEUS (RASPBERRY) SEED OIL 12F - Moisturizing 1

RUBUS IDAEUS (RASPBERRY) SEED OIL 12G - Night 2

SCLEROCARYA BIRREA SEED OIL 04E - Other Fragrance Preparation 2

SCLEROCARYA BIRREA SEED OIL 05A - Hair Conditioner 2

SCLEROCARYA BIRREA SEED OIL 05F - Shampoos (non-coloring) 1

SCLEROCARYA BIRREA SEED OIL 05G - Tonics, Dressings, and Other Hair Grooming Aids 3

SCLEROCARYA BIRREA SEED OIL 07E - Lipstick 6

SCLEROCARYA BIRREA SEED OIL 10E - Other Personal Cleanliness Products 2

SCLEROCARYA BIRREA SEED OIL 12A - Cleansing 1

SCLEROCARYA BIRREA SEED OIL 12C - Face and Neck (exc shave) 1

SCLEROCARYA BIRREA SEED OIL 12D - Body and Hand (exc shave) 3

SCLEROCARYA BIRREA SEED OIL 12F - Moisturizing 5

SCLEROCARYA BIRREA SEED OIL 12G - Night 2

SCLEROCARYA BIRREA SEED OIL 12J - Other Skin Care Preps 1

SOLANUM LYCOPERSICUM (TOMATO) SEED OIL 12C - Face and Neck (exc shave) 1

THEOBROMA CACAO (COCOA) SEED BUTTER 01B - Baby Lotions, Oils, Powders, and Creams 8

THEOBROMA CACAO (COCOA) SEED BUTTER 01C - Other Baby Products 4

THEOBROMA CACAO (COCOA) SEED BUTTER 02D - Other Bath Preparations 2

THEOBROMA CACAO (COCOA) SEED BUTTER 03A - Eyebrow Pencil 1

THEOBROMA CACAO (COCOA) SEED BUTTER 03B - Eyeliner 3

THEOBROMA CACAO (COCOA) SEED BUTTER 03D - Eye Lotion 5

THEOBROMA CACAO (COCOA) SEED BUTTER 03E - Eye Makeup Remover 1

THEOBROMA CACAO (COCOA) SEED BUTTER 03G - Other Eye Makeup Preparations 1

THEOBROMA CACAO (COCOA) SEED BUTTER 05A - Hair Conditioner 10

THEOBROMA CACAO (COCOA) SEED BUTTER 05C - Hair Straighteners 7

THEOBROMA CACAO (COCOA) SEED BUTTER 05F - Shampoos (non-coloring) 2

THEOBROMA CACAO (COCOA) SEED BUTTER 05G - Tonics, Dressings, and Other Hair Grooming Aids 2

THEOBROMA CACAO (COCOA) SEED BUTTER 05I - Other Hair Preparations 3

THEOBROMA CACAO (COCOA) SEED BUTTER 07A - Blushers (all types) 2

THEOBROMA CACAO (COCOA) SEED BUTTER 07E - Lipstick 33

THEOBROMA CACAO (COCOA) SEED BUTTER 07F - Makeup Bases 5

THEOBROMA CACAO (COCOA) SEED BUTTER 07G - Rouges 1

THEOBROMA CACAO (COCOA) SEED BUTTER 07I - Other Makeup Preparations 10



THEOBROMA CACAO (COCOA) SEED BUTTER 08B - Cuticle Softeners 1

THEOBROMA CACAO (COCOA) SEED BUTTER 10A - Bath Soaps and Detergents 26

THEOBROMA CACAO (COCOA) SEED BUTTER 10E - Other Personal Cleanliness Products 9

THEOBROMA CACAO (COCOA) SEED BUTTER 11A - Aftershave Lotion 1

THEOBROMA CACAO (COCOA) SEED BUTTER 11B - Beard Softeners 1

THEOBROMA CACAO (COCOA) SEED BUTTER 11E - Shaving Cream 2

THEOBROMA CACAO (COCOA) SEED BUTTER 11G - Other Shaving Preparation Products 5

THEOBROMA CACAO (COCOA) SEED BUTTER 12A - Cleansing 4

THEOBROMA CACAO (COCOA) SEED BUTTER 12B - Depilatories 2

THEOBROMA CACAO (COCOA) SEED BUTTER 12C - Face and Neck (exc shave) 13

THEOBROMA CACAO (COCOA) SEED BUTTER 12D - Body and Hand (exc shave) 72

THEOBROMA CACAO (COCOA) SEED BUTTER 12E - Foot Powders and Sprays 2

THEOBROMA CACAO (COCOA) SEED BUTTER 12F - Moisturizing 147

THEOBROMA CACAO (COCOA) SEED BUTTER 12G - Night 7

THEOBROMA CACAO (COCOA) SEED BUTTER 12H - Paste Masks (mud packs) 5

THEOBROMA CACAO (COCOA) SEED BUTTER 12I - Skin Fresheners 4

THEOBROMA CACAO (COCOA) SEED BUTTER 12J - Other Skin Care Preps 26

THEOBROMA CACAO (COCOA) SEED BUTTER 13A - Suntan Gels, Creams, and Liquids 7

THEOBROMA CACAO (COCOA) SEED BUTTER 13B - Indoor Tanning Preparations 8

THEOBROMA GRANDIFLORUM SEED BUTTER 02B - Bubble Baths 4

THEOBROMA GRANDIFLORUM SEED BUTTER 02D - Other Bath Preparations 1

THEOBROMA GRANDIFLORUM SEED BUTTER 03A - Eyebrow Pencil 1

THEOBROMA GRANDIFLORUM SEED BUTTER 03B - Eyeliner 13

THEOBROMA GRANDIFLORUM SEED BUTTER 03D - Eye Lotion 1

THEOBROMA GRANDIFLORUM SEED BUTTER 03G - Other Eye Makeup Preparations 6

THEOBROMA GRANDIFLORUM SEED BUTTER 05A - Hair Conditioner 3

THEOBROMA GRANDIFLORUM SEED BUTTER 05F - Shampoos (non-coloring) 2

THEOBROMA GRANDIFLORUM SEED BUTTER 05G - Tonics, Dressings, and Other Hair Grooming Aids 2

THEOBROMA GRANDIFLORUM SEED BUTTER 05I - Other Hair Preparations 2

THEOBROMA GRANDIFLORUM SEED BUTTER 06H - Other Hair Coloring Preparation 3

THEOBROMA GRANDIFLORUM SEED BUTTER 07E - Lipstick 49

THEOBROMA GRANDIFLORUM SEED BUTTER 07I - Other Makeup Preparations 4

THEOBROMA GRANDIFLORUM SEED BUTTER 10A - Bath Soaps and Detergents 7

THEOBROMA GRANDIFLORUM SEED BUTTER 10E - Other Personal Cleanliness Products 12

THEOBROMA GRANDIFLORUM SEED BUTTER 11E - Shaving Cream 1

THEOBROMA GRANDIFLORUM SEED BUTTER 12A - Cleansing 1

THEOBROMA GRANDIFLORUM SEED BUTTER 12C - Face and Neck (exc shave) 6

THEOBROMA GRANDIFLORUM SEED BUTTER 12D - Body and Hand (exc shave) 6

THEOBROMA GRANDIFLORUM SEED BUTTER 12F - Moisturizing 25

THEOBROMA GRANDIFLORUM SEED BUTTER 12G - Night 1

THEOBROMA GRANDIFLORUM SEED BUTTER 12J - Other Skin Care Preps 2

THEOBROMA GRANDIFLORUM SEED BUTTER 13C - Other Suntan Preparations 1

TRITICUM VULGARE (WHEAT) GERM OIL UNSAPONIFIABLES03D - Eye Lotion 1

TRITICUM VULGARE (WHEAT) GERM OIL UNSAPONIFIABLES12C - Face and Neck (exc shave) 11

TRITICUM VULGARE (WHEAT) GERM OIL UNSAPONIFIABLES12D - Body and Hand (exc shave) 1

TRITICUM VULGARE (WHEAT) GERM OIL UNSAPONIFIABLES12F - Moisturizing 2

TRITICUM VULGARE (WHEAT) GERM OIL UNSAPONIFIABLES12G - Night 1

TRITICUM VULGARE (WHEAT) GERM OIL UNSAPONIFIABLES13C - Other Suntan Preparations 1

WHEAT GERM ACID 05A - Hair Conditioner 13

WHEAT GERM ACID 05G - Tonics, Dressings, and Other Hair Grooming Aids 2

WHEAT GERM ACID 05I - Other Hair Preparations 1

VACCINIUM MACROCARPON (CRANBERRY) SEED OIL 03D - Eye Lotion 2

VACCINIUM MACROCARPON (CRANBERRY) SEED OIL 05A - Hair Conditioner 1

VACCINIUM MACROCARPON (CRANBERRY) SEED OIL 05I - Other Hair Preparations 3

VACCINIUM MACROCARPON (CRANBERRY) SEED OIL 10E - Other Personal Cleanliness Products 1

VACCINIUM MACROCARPON (CRANBERRY) SEED OIL 12C - Face and Neck (exc shave) 2

VACCINIUM MACROCARPON (CRANBERRY) SEED OIL 12D - Body and Hand (exc shave) 2



VACCINIUM MACROCARPON (CRANBERRY) SEED OIL 12F - Moisturizing 3

VACCINIUM MACROCARPON (CRANBERRY) SEED OIL 12G - Night 3

VACCINIUM MACROCARPON (CRANBERRY) SEED OIL 12H - Paste Masks (mud packs) 1

VACCINIUM MACROCARPON (CRANBERRY) SEED OIL 12J - Other Skin Care Preps 3

VACCINIUM OXYCOCCOS (CRANBERRY) SEED OIL 12F - Moisturizing 1

VACCINIUM OXYCOCCOS SEED OIL 12A - Cleansing 1

VACCINIUM OXYCOCCOS SEED OIL 12D - Body and Hand (exc shave) 1

VACCINIUM OXYCOCCOS SEED OIL 12F - Moisturizing 1

VITIS VINIFERA (GRAPE) SEED OIL 01B - Baby Lotions, Oils, Powders, and Creams 4

VITIS VINIFERA (GRAPE) SEED OIL 01C - Other Baby Products 1

VITIS VINIFERA (GRAPE) SEED OIL 02A - Bath Oils, Tablets, and Salts 4

VITIS VINIFERA (GRAPE) SEED OIL 02D - Other Bath Preparations 3

VITIS VINIFERA (GRAPE) SEED OIL 03C - Eye Shadow 1

VITIS VINIFERA (GRAPE) SEED OIL 03D - Eye Lotion 4

VITIS VINIFERA (GRAPE) SEED OIL 03G - Other Eye Makeup Preparations 3

VITIS VINIFERA (GRAPE) SEED OIL 04E - Other Fragrance Preparation 6

VITIS VINIFERA (GRAPE) SEED OIL 05A - Hair Conditioner 17

VITIS VINIFERA (GRAPE) SEED OIL 05F - Shampoos (non-coloring) 6

VITIS VINIFERA (GRAPE) SEED OIL 05G - Tonics, Dressings, and Other Hair Grooming Aids 9

VITIS VINIFERA (GRAPE) SEED OIL 05I - Other Hair Preparations 14

VITIS VINIFERA (GRAPE) SEED OIL 06A - Hair Dyes and Colors (all types requiring caution statements and patch tests) 4

VITIS VINIFERA (GRAPE) SEED OIL 06D - Hair Shampoos (coloring) 1

VITIS VINIFERA (GRAPE) SEED OIL 06G - Hair Bleaches 2

VITIS VINIFERA (GRAPE) SEED OIL 06H - Other Hair Coloring Preparation 3

VITIS VINIFERA (GRAPE) SEED OIL 07A - Blushers (all types) 1

VITIS VINIFERA (GRAPE) SEED OIL 07B - Face Powders 2

VITIS VINIFERA (GRAPE) SEED OIL 07E - Lipstick 34

VITIS VINIFERA (GRAPE) SEED OIL 07I - Other Makeup Preparations 6

VITIS VINIFERA (GRAPE) SEED OIL 08B - Cuticle Softeners 2

VITIS VINIFERA (GRAPE) SEED OIL 08C - Nail Creams and Lotions 3

VITIS VINIFERA (GRAPE) SEED OIL 08E - Nail Polish and Enamel 1

VITIS VINIFERA (GRAPE) SEED OIL 08G - Other Manicuring Preparations 2

VITIS VINIFERA (GRAPE) SEED OIL 10A - Bath Soaps and Detergents 15

VITIS VINIFERA (GRAPE) SEED OIL 10E - Other Personal Cleanliness Products 19

VITIS VINIFERA (GRAPE) SEED OIL 11A - Aftershave Lotion 1

VITIS VINIFERA (GRAPE) SEED OIL 11D - Preshave Lotions (all types) 1

VITIS VINIFERA (GRAPE) SEED OIL 11E - Shaving Cream 3

VITIS VINIFERA (GRAPE) SEED OIL 11G - Other Shaving Preparation Products 2

VITIS VINIFERA (GRAPE) SEED OIL 12A - Cleansing 11

VITIS VINIFERA (GRAPE) SEED OIL 12C - Face and Neck (exc shave) 18

VITIS VINIFERA (GRAPE) SEED OIL 12D - Body and Hand (exc shave) 59

VITIS VINIFERA (GRAPE) SEED OIL 12F - Moisturizing 134

VITIS VINIFERA (GRAPE) SEED OIL 12G - Night 15

VITIS VINIFERA (GRAPE) SEED OIL 12H - Paste Masks (mud packs) 6

VITIS VINIFERA (GRAPE) SEED OIL 12I - Skin Fresheners 5

VITIS VINIFERA (GRAPE) SEED OIL 12J - Other Skin Care Preps 27

VITIS VINIFERA (GRAPE) SEED OIL 13A - Suntan Gels, Creams, and Liquids 1

VITIS VINIFERA (GRAPE) SEED OIL 13B - Indoor Tanning Preparations 15

SODIUM GRAPESEEDATE 12J - Other Skin Care Preps 4

HYDROGENATED GRAPESEED OIL 05A - Hair Conditioner 1

HYDROGENATED GRAPESEED OIL 07E - Lipstick 1

HYDROGENATED GRAPESEED OIL 07I - Other Makeup Preparations 1

HYDROGENATED GRAPESEED OIL 08B - Cuticle Softeners 1

HYDROGENATED GRAPESEED OIL 10A - Bath Soaps and Detergents 1

HYDROGENATED GRAPESEED OIL 12A - Cleansing 1

HYDROGENATED GRAPESEED OIL 13A - Suntan Gels, Creams, and Liquids 1



BASSIA LATIFOLIA SEED BUTTER 03C - Eye Shadow 4

BASSIA LATIFOLIA SEED BUTTER 07A - Blushers (all types) 1

BASSIA LATIFOLIA SEED BUTTER 07B - Face Powders 5

BASSIA LATIFOLIA SEED BUTTER 10A - Bath Soaps and Detergents 1

BASSIA LATIFOLIA SEED BUTTER 10E - Other Personal Cleanliness Products 4

BASSIA LATIFOLIA SEED BUTTER 12F - Moisturizing 7

CAMELLIA KISSI SEED OIL 02A - Bath Oils, Tablets, and Salts 1

CAMELLIA KISSI SEED OIL 03C - Eye Shadow 4

CAMELLIA KISSI SEED OIL 05A - Hair Conditioner 3

CAMELLIA KISSI SEED OIL 05E - Rinses (non-coloring) 1

CAMELLIA KISSI SEED OIL 05F - Shampoos (non-coloring) 2

CAMELLIA KISSI SEED OIL 05G - Tonics, Dressings, and Other Hair Grooming Aids 2

CAMELLIA KISSI SEED OIL 05I - Other Hair Preparations 3

CAMELLIA KISSI SEED OIL 07A - Blushers (all types) 2

CAMELLIA KISSI SEED OIL 07B - Face Powders 1

CAMELLIA KISSI SEED OIL 07E - Lipstick 1

CAMELLIA KISSI SEED OIL 10A - Bath Soaps and Detergents 1

CAMELLIA KISSI SEED OIL 12A - Cleansing 4

CAMELLIA KISSI SEED OIL 12C - Face and Neck (exc shave) 3

CAMELLIA KISSI SEED OIL 12D - Body and Hand (exc shave) 7

CAMELLIA KISSI SEED OIL 12F - Moisturizing 7

CAMELLIA KISSI SEED OIL 12G - Night 2

CAMELLIA KISSI SEED OIL 12H - Paste Masks (mud packs) 1

CAMELLIA KISSI SEED OIL 12J - Other Skin Care Preps 2

CRAMBE ABYSSINICA SEED OIL 03G - Other Eye Makeup Preparations 1

CRAMBE ABYSSINICA SEED OIL 05A - Hair Conditioner 5

CRAMBE ABYSSINICA SEED OIL 05C - Hair Straighteners 1

CRAMBE ABYSSINICA SEED OIL 05F - Shampoos (non-coloring) 1

CRAMBE ABYSSINICA SEED OIL 05G - Tonics, Dressings, and Other Hair Grooming Aids 5

CRAMBE ABYSSINICA SEED OIL 05I - Other Hair Preparations 2

CRAMBE ABYSSINICA SEED OIL 06H - Other Hair Coloring Preparation 4

CRAMBE ABYSSINICA SEED OIL 07E - Lipstick 1

CRAMBE ABYSSINICA SEED OIL 12C - Face and Neck (exc shave) 2

CRAMBE ABYSSINICA SEED OIL 12D - Body and Hand (exc shave) 1

CRAMBE ABYSSINICA SEED OIL 12G - Night 3

GARCINIA INDICA SEED BUTTER 03D - Eye Lotion 1

GARCINIA INDICA SEED BUTTER 07E - Lipstick 3

GARCINIA INDICA SEED BUTTER 07I - Other Makeup Preparations 5

GARCINIA INDICA SEED BUTTER 10A - Bath Soaps and Detergents 1

GARCINIA INDICA SEED BUTTER 11F - Shaving Soap 2

GARCINIA INDICA SEED BUTTER 12C - Face and Neck (exc shave) 2

GARCINIA INDICA SEED BUTTER 12D - Body and Hand (exc shave) 2

GARCINIA INDICA SEED BUTTER 12F - Moisturizing 9

GARCINIA INDICA SEED BUTTER 12J - Other Skin Care Preps 5

HIPPOPHAE RHAMNOIDES FRUIT OIL 03D - Eye Lotion 1

HIPPOPHAE RHAMNOIDES FRUIT OIL 08G - Other Manicuring Preparations 1

HIPPOPHAE RHAMNOIDES FRUIT OIL 12C - Face and Neck (exc shave) 3

HIPPOPHAE RHAMNOIDES FRUIT OIL 12F - Moisturizing 2

HIPPOPHAE RHAMNOIDES OIL 05A - Hair Conditioner 3

HIPPOPHAE RHAMNOIDES OIL 05F - Shampoos (non-coloring) 1

HIPPOPHAE RHAMNOIDES OIL 05G - Tonics, Dressings, and Other Hair Grooming Aids 2

HIPPOPHAE RHAMNOIDES OIL 08A - Basecoats and Undercoats 1

HIPPOPHAE RHAMNOIDES OIL 08B - Cuticle Softeners 1

HIPPOPHAE RHAMNOIDES OIL 08E - Nail Polish and Enamel 3



HIPPOPHAE RHAMNOIDES OIL 08G - Other Manicuring Preparations 3

HIPPOPHAE RHAMNOIDES OIL 10E - Other Personal Cleanliness Products 1

LUFFA CYLINDRICA SEED OIL 03C - Eye Shadow 1

LUFFA CYLINDRICA SEED OIL 07A - Blushers (all types) 3

LUFFA CYLINDRICA SEED OIL 07B - Face Powders 1

LUFFA CYLINDRICA SEED OIL 07E - Lipstick 9

LUFFA CYLINDRICA SEED OIL 12C - Face and Neck (exc shave) 2

LUFFA CYLINDRICA SEED OIL 12F - Moisturizing 1

LUFFA CYLINDRICA SEED OIL 12G - Night 1

LUFFA CYLINDRICA SEED OIL 13B - Indoor Tanning Preparations 1

LUFFA CYLINDRICA SEED OIL 13C - Other Suntan Preparations 2

LUPINUS ALBUS SEED OIL 13C - Other Suntan Preparations 1

LYCIUM BARBARUM SEED OIL 03G - Other Eye Makeup Preparations 1

LYCIUM BARBARUM SEED OIL 07E - Lipstick 1

ORBIGNYA SPECIOSA KERNEL OIL 05A - Hair Conditioner 2

ORBIGNYA SPECIOSA KERNEL OIL 05F - Shampoos (non-coloring) 2

ORBIGNYA SPECIOSA KERNEL OIL 05I - Other Hair Preparations 1

ORBIGNYA SPECIOSA KERNEL OIL 06H - Other Hair Coloring Preparation 3

PASSIFLORA EDULIS SEED OIL 03C - Eye Shadow 1

PASSIFLORA EDULIS SEED OIL 03D - Eye Lotion 2

PASSIFLORA EDULIS SEED OIL 05A - Hair Conditioner 2

PASSIFLORA EDULIS SEED OIL 05B - Hair Spray (aerosol fixatives) 3

PASSIFLORA EDULIS SEED OIL 05F - Shampoos (non-coloring) 1

PASSIFLORA EDULIS SEED OIL 05G - Tonics, Dressings, and Other Hair Grooming Aids 1

PASSIFLORA EDULIS SEED OIL 05I - Other Hair Preparations 3

PASSIFLORA EDULIS SEED OIL 06H - Other Hair Coloring Preparation 3

PASSIFLORA EDULIS SEED OIL 07B - Face Powders 2

PASSIFLORA EDULIS SEED OIL 07E - Lipstick 14

PASSIFLORA EDULIS SEED OIL 10E - Other Personal Cleanliness Products 1

PASSIFLORA EDULIS SEED OIL 12A - Cleansing 2

PASSIFLORA EDULIS SEED OIL 12C - Face and Neck (exc shave) 6

PASSIFLORA EDULIS SEED OIL 12D - Body and Hand (exc shave) 2

PASSIFLORA EDULIS SEED OIL 12F - Moisturizing 16

PASSIFLORA EDULIS SEED OIL 12G - Night 1

PASSIFLORA EDULIS SEED OIL 12J - Other Skin Care Preps 2

PUNICA GRANATUM SEED OIL 03D - Eye Lotion 2

PUNICA GRANATUM SEED OIL 07A - Blushers (all types) 1

PUNICA GRANATUM SEED OIL 07E - Lipstick 30

PUNICA GRANATUM SEED OIL 10A - Bath Soaps and Detergents 2

PUNICA GRANATUM SEED OIL 12C - Face and Neck (exc shave) 3

PUNICA GRANATUM SEED OIL 12F - Moisturizing 5

PUNICA GRANATUM SEED OIL 12G - Night 1

PUNICA GRANATUM SEED OIL 12J - Other Skin Care Preps 2

ROSA CANINA FRUIT OIL 02B - Bubble Baths 1

ROSA CANINA FRUIT OIL 03B - Eyeliner 4

ROSA CANINA FRUIT OIL 03D - Eye Lotion 7

ROSA CANINA FRUIT OIL 03F - Mascara 2

ROSA CANINA FRUIT OIL 03G - Other Eye Makeup Preparations 4

ROSA CANINA FRUIT OIL 04E - Other Fragrance Preparation 1

ROSA CANINA FRUIT OIL 05A - Hair Conditioner 4

ROSA CANINA FRUIT OIL 05F - Shampoos (non-coloring) 2



ROSA CANINA FRUIT OIL 05G - Tonics, Dressings, and Other Hair Grooming Aids 1

ROSA CANINA FRUIT OIL 05I - Other Hair Preparations 2

ROSA CANINA FRUIT OIL 07C - Foundations 3

ROSA CANINA FRUIT OIL 07E - Lipstick 7

ROSA CANINA FRUIT OIL 07I - Other Makeup Preparations 2

ROSA CANINA FRUIT OIL 08G - Other Manicuring Preparations 1

ROSA CANINA FRUIT OIL 10A - Bath Soaps and Detergents 3

ROSA CANINA FRUIT OIL 12A - Cleansing 4

ROSA CANINA FRUIT OIL 12C - Face and Neck (exc shave) 23

ROSA CANINA FRUIT OIL 12D - Body and Hand (exc shave) 7

ROSA CANINA FRUIT OIL 12F - Moisturizing 22

ROSA CANINA FRUIT OIL 12G - Night 9

ROSA CANINA FRUIT OIL 12H - Paste Masks (mud packs) 1

ROSA CANINA FRUIT OIL 12I - Skin Fresheners 7

ROSA CANINA FRUIT OIL 12J - Other Skin Care Preps 3

ROSA CANINA FRUIT OIL 13B - Indoor Tanning Preparations 1

RUBUS CHAMAEMORUS SEED OIL 12C - Face and Neck (exc shave) 2

RUBUS CHAMAEMORUS SEED OIL 12G - Night 1

VACCINIUM MYRTILLUS SEED OIL 07E - Lipstick 29

VACCINIUM MYRTILLUS SEED OIL 12A - Cleansing 1

VACCINIUM MYRTILLUS SEED OIL 12D - Body and Hand (exc shave) 1

VACCINIUM MYRTILLUS SEED OIL 12F - Moisturizing 2

VACCINIUM VITIS-IDAEA SEED OIL 08A - Basecoats and Undercoats 1

VACCINIUM VITIS-IDAEA SEED OIL 08B - Cuticle Softeners 1

VACCINIUM VITIS-IDAEA SEED OIL 08E - Nail Polish and Enamel 3

VACCINIUM VITIS-IDAEA SEED OIL 08G - Other Manicuring Preparations 3

VACCINIUM VITIS-IDAEA SEED OIL 12D - Body and Hand (exc shave) 1

VANILLA PLANIFOLIA FRUIT OIL 03D - Eye Lotion 1

VANILLA PLANIFOLIA FRUIT OIL 03G - Other Eye Makeup Preparations 1

VANILLA PLANIFOLIA FRUIT OIL 07I - Other Makeup Preparations 2

VANILLA PLANIFOLIA FRUIT OIL 10E - Other Personal Cleanliness Products 1

VANILLA PLANIFOLIA FRUIT OIL 12F - Moisturizing 4



CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 01B - Baby Lotions, Oils, Powders, and Creams 5

CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 01C - Other Baby Products 1

CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 02A - Bath Oils, Tablets, and Salts 2

CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 02D - Other Bath Preparations 1

CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 03B - Eyeliner 6

CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 03C - Eye Shadow 4

CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 03D - Eye Lotion 2

CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 03G - Other Eye Makeup Preparations 3

CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 04E - Other Fragrance Preparation 5

CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 05A - Hair Conditioner 26

CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 05C - Hair Straighteners 1

CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 05F - Shampoos (non-coloring) 10

CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 05G - Tonics, Dressings, and Other Hair Grooming Aids 37

CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 05I - Other Hair Preparations 5

CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 06H - Other Hair Coloring Preparation 2

CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 07A - Blushers (all types) 11

CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 07B - Face Powders 3

CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 07C - Foundations 3

CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 07E - Lipstick 83

CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 07F - Makeup Bases 1

CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 07I - Other Makeup Preparations 7

CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 08A - Basecoats and Undercoats 1

CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 08B - Cuticle Softeners 4

CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 08C - Nail Creams and Lotions 2

CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 08E - Nail Polish and Enamel 16

CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 08G - Other Manicuring Preparations 9

CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 10A - Bath Soaps and Detergents 19

CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 10E - Other Personal Cleanliness Products 12

CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 11A - Aftershave Lotion 1

CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 11D - Preshave Lotions (all types) 1

CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 11E - Shaving Cream 1

CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 12A - Cleansing 22

CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 12B - Depilatories 4

CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 12C - Face and Neck (exc shave) 15

CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 12D - Body and Hand (exc shave) 62

CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 12F - Moisturizing 70

CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 12G - Night 5

CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 12H - Paste Masks (mud packs) 5

CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 12I - Skin Fresheners 3

CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 12J - Other Skin Care Preps 33

CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 13B - Indoor Tanning Preparations 4

CARTHAMUS TINCTORIUS (SAFFLOWER) SEED OIL 13C - Other Suntan Preparations 1

HYBRID SAFFLOWER OIL 05A - Hair Conditioner 2

HYBRID SAFFLOWER OIL 12A - Cleansing 1

HYBRID SAFFLOWER OIL 12C - Face and Neck (exc shave) 1

HYBRID SAFFLOWER OIL 12D - Body and Hand (exc shave) 2

HYBRID SAFFLOWER OIL 12F - Moisturizing 4

HYBRID SAFFLOWER OIL 12G - Night 1

HYBRID SAFFLOWER OIL 12H - Paste Masks (mud packs) 1

HYBRID SAFFLOWER OIL 12J - Other Skin Care Preps 1

HYBRID SAFFLOWER OIL 13A - Suntan Gels, Creams, and Liquids 1

ELAEIS GUINEENSIS (PALM) OIL 01B - Baby Lotions, Oils, Powders, and Creams 1

ELAEIS GUINEENSIS (PALM) OIL 01C - Other Baby Products 1

ELAEIS GUINEENSIS (PALM) OIL 03A - Eyebrow Pencil 5

ELAEIS GUINEENSIS (PALM) OIL 03B - Eyeliner 1

ELAEIS GUINEENSIS (PALM) OIL 03D - Eye Lotion 3

ELAEIS GUINEENSIS (PALM) OIL 03G - Other Eye Makeup Preparations 3

ELAEIS GUINEENSIS (PALM) OIL 05A - Hair Conditioner 16

ELAEIS GUINEENSIS (PALM) OIL 05B - Hair Spray (aerosol fixatives) 3

ELAEIS GUINEENSIS (PALM) OIL 05F - Shampoos (non-coloring) 3

ELAEIS GUINEENSIS (PALM) OIL 05G - Tonics, Dressings, and Other Hair Grooming Aids 4



ELAEIS GUINEENSIS (PALM) OIL 05I - Other Hair Preparations 17

ELAEIS GUINEENSIS (PALM) OIL 07E - Lipstick 11

ELAEIS GUINEENSIS (PALM) OIL 07H - Makeup Fixatives 3

ELAEIS GUINEENSIS (PALM) OIL 07I - Other Makeup Preparations 8

ELAEIS GUINEENSIS (PALM) OIL 10A - Bath Soaps and Detergents 59

ELAEIS GUINEENSIS (PALM) OIL 10E - Other Personal Cleanliness Products 9

ELAEIS GUINEENSIS (PALM) OIL 11A - Aftershave Lotion 7

ELAEIS GUINEENSIS (PALM) OIL 11E - Shaving Cream 4

ELAEIS GUINEENSIS (PALM) OIL 12A - Cleansing 8

ELAEIS GUINEENSIS (PALM) OIL 12C - Face and Neck (exc shave) 17

ELAEIS GUINEENSIS (PALM) OIL 12D - Body and Hand (exc shave) 34

ELAEIS GUINEENSIS (PALM) OIL 12F - Moisturizing 28

ELAEIS GUINEENSIS (PALM) OIL 12G - Night 6

ELAEIS GUINEENSIS (PALM) OIL 12H - Paste Masks (mud packs) 2

ELAEIS GUINEENSIS (PALM) OIL 12J - Other Skin Care Preps 13

ELAEIS GUINEENSIS (PALM) OIL 13B - Indoor Tanning Preparations 5

ELAEIS GUINEENSIS (PALM) OIL 13C - Other Suntan Preparations 1

ELAEIS GUINEENSIS (PALM) KERNEL OIL 02B - Bubble Baths 1

ELAEIS GUINEENSIS (PALM) KERNEL OIL 03A - Eyebrow Pencil 5

ELAEIS GUINEENSIS (PALM) KERNEL OIL 03B - Eyeliner 1

ELAEIS GUINEENSIS (PALM) KERNEL OIL 03D - Eye Lotion 2

ELAEIS GUINEENSIS (PALM) KERNEL OIL 03G - Other Eye Makeup Preparations 2

ELAEIS GUINEENSIS (PALM) KERNEL OIL 05A - Hair Conditioner 5

ELAEIS GUINEENSIS (PALM) KERNEL OIL 05F - Shampoos (non-coloring) 1

ELAEIS GUINEENSIS (PALM) KERNEL OIL 07E - Lipstick 6

ELAEIS GUINEENSIS (PALM) KERNEL OIL 07H - Makeup Fixatives 3

ELAEIS GUINEENSIS (PALM) KERNEL OIL 07I - Other Makeup Preparations 8

ELAEIS GUINEENSIS (PALM) KERNEL OIL 10A - Bath Soaps and Detergents 9

ELAEIS GUINEENSIS (PALM) KERNEL OIL 12A - Cleansing 1

ELAEIS GUINEENSIS (PALM) KERNEL OIL 12C - Face and Neck (exc shave) 7

ELAEIS GUINEENSIS (PALM) KERNEL OIL 12D - Body and Hand (exc shave) 9

ELAEIS GUINEENSIS (PALM) KERNEL OIL 12F - Moisturizing 12

ELAEIS GUINEENSIS (PALM) KERNEL OIL 12G - Night 2

ELAEIS GUINEENSIS (PALM) KERNEL OIL 12J - Other Skin Care Preps 1

ELAEIS GUINEENSIS (PALM) KERNEL OIL 13B - Indoor Tanning Preparations 2

HYDROGENATED PALM OIL 03A - Eyebrow Pencil 13

HYDROGENATED PALM OIL 03B - Eyeliner 9

HYDROGENATED PALM OIL 03D - Eye Lotion 2

HYDROGENATED PALM OIL 03F - Mascara 29

HYDROGENATED PALM OIL 03G - Other Eye Makeup Preparations 8

HYDROGENATED PALM OIL 07C - Foundations 1

HYDROGENATED PALM OIL 07E - Lipstick 12

HYDROGENATED PALM OIL 07H - Makeup Fixatives 3

HYDROGENATED PALM OIL 07I - Other Makeup Preparations 13

HYDROGENATED PALM OIL 10A - Bath Soaps and Detergents 15

HYDROGENATED PALM OIL 10E - Other Personal Cleanliness Products 2

HYDROGENATED PALM OIL 11F - Shaving Soap 1

HYDROGENATED PALM OIL 12C - Face and Neck (exc shave) 9

HYDROGENATED PALM OIL 12D - Body and Hand (exc shave) 9

HYDROGENATED PALM OIL 12F - Moisturizing 17

HYDROGENATED PALM OIL 12G - Night 4

HYDROGENATED PALM OIL 12J - Other Skin Care Preps 2

HYDROGENATED PALM OIL 13A - Suntan Gels, Creams, and Liquids 1

HYDROGENATED PALM OIL 13B - Indoor Tanning Preparations 2

HYDROGENATED PALM KERNEL OIL 03A - Eyebrow Pencil 1

HYDROGENATED PALM KERNEL OIL 03G - Other Eye Makeup Preparations 1

HYDROGENATED PALM KERNEL OIL 04E - Other Fragrance Preparation 1

HYDROGENATED PALM KERNEL OIL 07E - Lipstick 5

HYDROGENATED PALM KERNEL OIL 10A - Bath Soaps and Detergents 2



HYDROGENATED PALM KERNEL OIL 12C - Face and Neck (exc shave) 6

HYDROGENATED PALM KERNEL OIL 12D - Body and Hand (exc shave) 10

HYDROGENATED PALM KERNEL OIL 12F - Moisturizing 13

HYDROGENATED PALM KERNEL OIL 12G - Night 1

HYDROGENATED PALM KERNEL OIL 12J - Other Skin Care Preps 5

HYDROGENATED PALM KERNEL OIL 13A - Suntan Gels, Creams, and Liquids 2

GOSSYPIUM HERBACEUM (COTTON) SEED OIL 03B - Eyeliner 2

GOSSYPIUM HERBACEUM (COTTON) SEED OIL 03F - Mascara 2

GOSSYPIUM HERBACEUM (COTTON) SEED OIL 04B - Perfumes 1

GOSSYPIUM HERBACEUM (COTTON) SEED OIL 04E - Other Fragrance Preparation 10

GOSSYPIUM HERBACEUM (COTTON) SEED OIL 05I - Other Hair Preparations 2

GOSSYPIUM HERBACEUM (COTTON) SEED OIL 07C - Foundations 1

GOSSYPIUM HERBACEUM (COTTON) SEED OIL 07E - Lipstick 9

GOSSYPIUM HERBACEUM (COTTON) SEED OIL 08B - Cuticle Softeners 1

GOSSYPIUM HERBACEUM (COTTON) SEED OIL 10A - Bath Soaps and Detergents 5

GOSSYPIUM HERBACEUM (COTTON) SEED OIL 10B - Deodorants (underarm) 1

GOSSYPIUM HERBACEUM (COTTON) SEED OIL 10E - Other Personal Cleanliness Products 2

GOSSYPIUM HERBACEUM (COTTON) SEED OIL 11E - Shaving Cream 4

GOSSYPIUM HERBACEUM (COTTON) SEED OIL 12A - Cleansing 3

GOSSYPIUM HERBACEUM (COTTON) SEED OIL 12C - Face and Neck (exc shave) 3

GOSSYPIUM HERBACEUM (COTTON) SEED OIL 12D - Body and Hand (exc shave) 14

GOSSYPIUM HERBACEUM (COTTON) SEED OIL 12E - Foot Powders and Sprays 1

GOSSYPIUM HERBACEUM (COTTON) SEED OIL 12F - Moisturizing 10

GOSSYPIUM HERBACEUM (COTTON) SEED OIL 12H - Paste Masks (mud packs) 1

GOSSYPIUM HERBACEUM (COTTON) SEED OIL 12J - Other Skin Care Preps 8

GOSSYPIUM HERBACEUM (COTTON) SEED OIL 13B - Indoor Tanning Preparations 3

HYDROGENATED COTTONSEED OIL 01B - Baby Lotions, Oils, Powders, and Creams 8

HYDROGENATED COTTONSEED OIL 03A - Eyebrow Pencil 32

HYDROGENATED COTTONSEED OIL 03B - Eyeliner 87

HYDROGENATED COTTONSEED OIL 03C - Eye Shadow 18

HYDROGENATED COTTONSEED OIL 03D - Eye Lotion 1

HYDROGENATED COTTONSEED OIL 03F - Mascara 2

HYDROGENATED COTTONSEED OIL 03G - Other Eye Makeup Preparations 15

HYDROGENATED COTTONSEED OIL 05A - Hair Conditioner 3

HYDROGENATED COTTONSEED OIL 05G - Tonics, Dressings, and Other Hair Grooming Aids 1

HYDROGENATED COTTONSEED OIL 07D - Leg and Body Paints 1

HYDROGENATED COTTONSEED OIL 07E - Lipstick 168

HYDROGENATED COTTONSEED OIL 07I - Other Makeup Preparations 13

HYDROGENATED COTTONSEED OIL 12F - Moisturizing 9

HYDROGENATED COTTONSEED OIL 12H - Paste Masks (mud packs) 1

HYDROGENATED COTTONSEED OIL 12I - Skin Fresheners 1

HYDROGENATED COTTONSEED OIL 12J - Other Skin Care Preps 2

ORYZA SATIVA (RICE) BRAN OIL 01B - Baby Lotions, Oils, Powders, and Creams 1

ORYZA SATIVA (RICE) BRAN OIL 01C - Other Baby Products 1

ORYZA SATIVA (RICE) BRAN OIL 02A - Bath Oils, Tablets, and Salts 6

ORYZA SATIVA (RICE) BRAN OIL 02B - Bubble Baths 1

ORYZA SATIVA (RICE) BRAN OIL 02D - Other Bath Preparations 10

ORYZA SATIVA (RICE) BRAN OIL 03D - Eye Lotion 1

ORYZA SATIVA (RICE) BRAN OIL 03F - Mascara 3

ORYZA SATIVA (RICE) BRAN OIL 03G - Other Eye Makeup Preparations 1

ORYZA SATIVA (RICE) BRAN OIL 04E - Other Fragrance Preparation 6

ORYZA SATIVA (RICE) BRAN OIL 05A - Hair Conditioner 13

ORYZA SATIVA (RICE) BRAN OIL 05B - Hair Spray (aerosol fixatives) 4

ORYZA SATIVA (RICE) BRAN OIL 05E - Rinses (non-coloring) 1

ORYZA SATIVA (RICE) BRAN OIL 05F - Shampoos (non-coloring) 10

ORYZA SATIVA (RICE) BRAN OIL 05G - Tonics, Dressings, and Other Hair Grooming Aids 11

ORYZA SATIVA (RICE) BRAN OIL 05I - Other Hair Preparations 3

ORYZA SATIVA (RICE) BRAN OIL 07C - Foundations 1

ORYZA SATIVA (RICE) BRAN OIL 07E - Lipstick 17



ORYZA SATIVA (RICE) BRAN OIL 07I - Other Makeup Preparations 2

ORYZA SATIVA (RICE) BRAN OIL 08B - Cuticle Softeners 2

ORYZA SATIVA (RICE) BRAN OIL 08G - Other Manicuring Preparations 3

ORYZA SATIVA (RICE) BRAN OIL 10A - Bath Soaps and Detergents 39

ORYZA SATIVA (RICE) BRAN OIL 10E - Other Personal Cleanliness Products 9

ORYZA SATIVA (RICE) BRAN OIL 11G - Other Shaving Preparation Products 1

ORYZA SATIVA (RICE) BRAN OIL 12A - Cleansing 9

ORYZA SATIVA (RICE) BRAN OIL 12C - Face and Neck (exc shave) 22

ORYZA SATIVA (RICE) BRAN OIL 12D - Body and Hand (exc shave) 50

ORYZA SATIVA (RICE) BRAN OIL 12E - Foot Powders and Sprays 1

ORYZA SATIVA (RICE) BRAN OIL 12F - Moisturizing 88

ORYZA SATIVA (RICE) BRAN OIL 12G - Night 11

ORYZA SATIVA (RICE) BRAN OIL 12H - Paste Masks (mud packs) 5

ORYZA SATIVA (RICE) BRAN OIL 12J - Other Skin Care Preps 34

ORYZA SATIVA (RICE) BRAN OIL 13A - Suntan Gels, Creams, and Liquids 1

ORYZA SATIVA (RICE) BRAN OIL 13B - Indoor Tanning Preparations 1

ORYZA SATIVA (RICE) BRAN OIL 13C - Other Suntan Preparations 3

ORYZA SATIVA (RICE) GERM OIL 02A - Bath Oils, Tablets, and Salts 1

ORYZA SATIVA (RICE) GERM OIL 03F - Mascara 2

ORYZA SATIVA (RICE) GERM OIL 07E - Lipstick 4

ORYZA SATIVA (RICE) GERM OIL 07I - Other Makeup Preparations 1

ORYZA SATIVA (RICE) GERM OIL 10E - Other Personal Cleanliness Products 1

ORYZA SATIVA (RICE) GERM OIL 12A - Cleansing 3

ORYZA SATIVA (RICE) GERM OIL 12C - Face and Neck (exc shave) 11

ORYZA SATIVA (RICE) GERM OIL 12D - Body and Hand (exc shave) 5

ORYZA SATIVA (RICE) GERM OIL 12F - Moisturizing 4

ORYZA SATIVA (RICE) GERM OIL 12J - Other Skin Care Preps 2

SESAMUM INDICUM (SESAME) SEED OIL 01B - Baby Lotions, Oils, Powders, and Creams 3

SESAMUM INDICUM (SESAME) SEED OIL 02A - Bath Oils, Tablets, and Salts 2

SESAMUM INDICUM (SESAME) SEED OIL 02D - Other Bath Preparations 3

SESAMUM INDICUM (SESAME) SEED OIL 03B - Eyeliner 2

SESAMUM INDICUM (SESAME) SEED OIL 03C - Eye Shadow 2

SESAMUM INDICUM (SESAME) SEED OIL 03D - Eye Lotion 4

SESAMUM INDICUM (SESAME) SEED OIL 03E - Eye Makeup Remover 1

SESAMUM INDICUM (SESAME) SEED OIL 03G - Other Eye Makeup Preparations 5

SESAMUM INDICUM (SESAME) SEED OIL 04C - Powders (dusting and talcum, excluding aftershave talc) 1

SESAMUM INDICUM (SESAME) SEED OIL 04E - Other Fragrance Preparation 1

SESAMUM INDICUM (SESAME) SEED OIL 05A - Hair Conditioner 12

SESAMUM INDICUM (SESAME) SEED OIL 05B - Hair Spray (aerosol fixatives) 3

SESAMUM INDICUM (SESAME) SEED OIL 05F - Shampoos (non-coloring) 16

SESAMUM INDICUM (SESAME) SEED OIL 05G - Tonics, Dressings, and Other Hair Grooming Aids 10

SESAMUM INDICUM (SESAME) SEED OIL 05H - Wave Sets 1

SESAMUM INDICUM (SESAME) SEED OIL 05I - Other Hair Preparations 17

SESAMUM INDICUM (SESAME) SEED OIL 07C - Foundations 11

SESAMUM INDICUM (SESAME) SEED OIL 07E - Lipstick 52

SESAMUM INDICUM (SESAME) SEED OIL 07F - Makeup Bases 23

SESAMUM INDICUM (SESAME) SEED OIL 07H - Makeup Fixatives 1

SESAMUM INDICUM (SESAME) SEED OIL 07I - Other Makeup Preparations 5

SESAMUM INDICUM (SESAME) SEED OIL 08B - Cuticle Softeners 2

SESAMUM INDICUM (SESAME) SEED OIL 08C - Nail Creams and Lotions 2

SESAMUM INDICUM (SESAME) SEED OIL 08G - Other Manicuring Preparations 3

SESAMUM INDICUM (SESAME) SEED OIL 10A - Bath Soaps and Detergents 20

SESAMUM INDICUM (SESAME) SEED OIL 10E - Other Personal Cleanliness Products 8

SESAMUM INDICUM (SESAME) SEED OIL 11A - Aftershave Lotion 3

SESAMUM INDICUM (SESAME) SEED OIL 11B - Beard Softeners 1

SESAMUM INDICUM (SESAME) SEED OIL 11D - Preshave Lotions (all types) 1

SESAMUM INDICUM (SESAME) SEED OIL 11E - Shaving Cream 4

SESAMUM INDICUM (SESAME) SEED OIL 12A - Cleansing 16

SESAMUM INDICUM (SESAME) SEED OIL 12C - Face and Neck (exc shave) 24

SESAMUM INDICUM (SESAME) SEED OIL 12D - Body and Hand (exc shave) 76

SESAMUM INDICUM (SESAME) SEED OIL 12F - Moisturizing 74



SESAMUM INDICUM (SESAME) SEED OIL 12G - Night 14

SESAMUM INDICUM (SESAME) SEED OIL 12H - Paste Masks (mud packs) 5

SESAMUM INDICUM (SESAME) SEED OIL 12J - Other Skin Care Preps 41

SESAMUM INDICUM (SESAME) SEED OIL 13A - Suntan Gels, Creams, and Liquids 6

SESAMUM INDICUM (SESAME) SEED OIL 13B - Indoor Tanning Preparations 3

SESAMUM INDICUM (SESAME) SEED OIL 13C - Other Suntan Preparations 2

SESAMUM INDICUM (SESAME) OIL UNSAPONIFIABLES 07E - Lipstick 11

SESAMUM INDICUM (SESAME) OIL UNSAPONIFIABLES 12C - Face and Neck (exc shave) 4

SESAMUM INDICUM (SESAME) OIL UNSAPONIFIABLES 12D - Body and Hand (exc shave) 1

SESAMUM INDICUM (SESAME) OIL UNSAPONIFIABLES 12F - Moisturizing 1

ZEA MAYS (CORN) OIL 01B - Baby Lotions, Oils, Powders, and Creams 5

ZEA MAYS (CORN) OIL 01C - Other Baby Products 3

ZEA MAYS (CORN) OIL 03C - Eye Shadow 17

ZEA MAYS (CORN) OIL 03D - Eye Lotion 7

ZEA MAYS (CORN) OIL 03E - Eye Makeup Remover 4

ZEA MAYS (CORN) OIL 03F - Mascara 1

ZEA MAYS (CORN) OIL 03G - Other Eye Makeup Preparations 6

ZEA MAYS (CORN) OIL 05A - Hair Conditioner 11

ZEA MAYS (CORN) OIL 05B - Hair Spray (aerosol fixatives) 1

ZEA MAYS (CORN) OIL 05E - Rinses (non-coloring) 1

ZEA MAYS (CORN) OIL 05F - Shampoos (non-coloring) 12

ZEA MAYS (CORN) OIL 05G - Tonics, Dressings, and Other Hair Grooming Aids 11

ZEA MAYS (CORN) OIL 05I - Other Hair Preparations 4

ZEA MAYS (CORN) OIL 06A - Hair Dyes and Colors (all types requiring caution statements and patch tests)178

ZEA MAYS (CORN) OIL 06B - Hair Tints 1

ZEA MAYS (CORN) OIL 06C - Hair Rinses (coloring) 1

ZEA MAYS (CORN) OIL 06G - Hair Bleaches 1

ZEA MAYS (CORN) OIL 06H - Other Hair Coloring Preparation 2

ZEA MAYS (CORN) OIL 07A - Blushers (all types) 22

ZEA MAYS (CORN) OIL 07B - Face Powders 31

ZEA MAYS (CORN) OIL 07C - Foundations 11

ZEA MAYS (CORN) OIL 07E - Lipstick 30

ZEA MAYS (CORN) OIL 07I - Other Makeup Preparations 7

ZEA MAYS (CORN) OIL 08B - Cuticle Softeners 1

ZEA MAYS (CORN) OIL 08E - Nail Polish and Enamel 1

ZEA MAYS (CORN) OIL 08G - Other Manicuring Preparations 1

ZEA MAYS (CORN) OIL 10A - Bath Soaps and Detergents 2

ZEA MAYS (CORN) OIL 10B - Deodorants (underarm) 4

ZEA MAYS (CORN) OIL 12A - Cleansing 13

ZEA MAYS (CORN) OIL 12C - Face and Neck (exc shave) 53

ZEA MAYS (CORN) OIL 12D - Body and Hand (exc shave) 34

ZEA MAYS (CORN) OIL 12F - Moisturizing 68

ZEA MAYS (CORN) OIL 12G - Night 11

ZEA MAYS (CORN) OIL 12H - Paste Masks (mud packs) 11

ZEA MAYS (CORN) OIL 12I - Skin Fresheners 2

ZEA MAYS (CORN) OIL 12J - Other Skin Care Preps 24

ZEA MAYS (CORN) OIL 13A - Suntan Gels, Creams, and Liquids 1

ZEA MAYS (CORN) OIL 13B - Indoor Tanning Preparations 2

ZEA MAYS (CORN) OIL 13C - Other Suntan Preparations 3

ZEA MAYS (CORN) GERM OIL 01B - Baby Lotions, Oils, Powders, and Creams 3

ZEA MAYS (CORN) GERM OIL 01C - Other Baby Products 1

ZEA MAYS (CORN) GERM OIL 02A - Bath Oils, Tablets, and Salts 4

ZEA MAYS (CORN) GERM OIL 05A - Hair Conditioner 1

ZEA MAYS (CORN) GERM OIL 05E - Rinses (non-coloring) 1

ZEA MAYS (CORN) GERM OIL 05F - Shampoos (non-coloring) 1

ZEA MAYS (CORN) GERM OIL 10A - Bath Soaps and Detergents 2

ZEA MAYS (CORN) GERM OIL 10E - Other Personal Cleanliness Products 1

ZEA MAYS (CORN) GERM OIL 12A - Cleansing 9

ZEA MAYS (CORN) GERM OIL 12C - Face and Neck (exc shave) 6



ZEA MAYS (CORN) GERM OIL 12D - Body and Hand (exc shave) 4

ZEA MAYS (CORN) GERM OIL 12F - Moisturizing 16

ZEA MAYS (CORN) GERM OIL 12J - Other Skin Care Preps 3

ZEA MAYS (CORN) GERM OIL 13B - Indoor Tanning Preparations 1

ZEA MAYS (CORN) OIL UNSAPONIFIABLES 12D - Body and Hand (exc shave) 1

PERSEA GRATISSIMA (AVOCADO) OIL 01B - Baby Lotions, Oils, Powders, and Creams 7

PERSEA GRATISSIMA (AVOCADO) OIL 01C - Other Baby Products 2

PERSEA GRATISSIMA (AVOCADO) OIL 02A - Bath Oils, Tablets, and Salts 23

PERSEA GRATISSIMA (AVOCADO) OIL 02B - Bubble Baths 1

PERSEA GRATISSIMA (AVOCADO) OIL 02D - Other Bath Preparations 1

PERSEA GRATISSIMA (AVOCADO) OIL 03A - Eyebrow Pencil 2

PERSEA GRATISSIMA (AVOCADO) OIL 03B - Eyeliner 3

PERSEA GRATISSIMA (AVOCADO) OIL 03C - Eye Shadow 1

PERSEA GRATISSIMA (AVOCADO) OIL 03D - Eye Lotion 12

PERSEA GRATISSIMA (AVOCADO) OIL 03E - Eye Makeup Remover 1

PERSEA GRATISSIMA (AVOCADO) OIL 03F - Mascara 2

PERSEA GRATISSIMA (AVOCADO) OIL 03G - Other Eye Makeup Preparations 3

PERSEA GRATISSIMA (AVOCADO) OIL 04E - Other Fragrance Preparation 7

PERSEA GRATISSIMA (AVOCADO) OIL 05A - Hair Conditioner 58

PERSEA GRATISSIMA (AVOCADO) OIL 05B - Hair Spray (aerosol fixatives) 4

PERSEA GRATISSIMA (AVOCADO) OIL 05C - Hair Straighteners 10

PERSEA GRATISSIMA (AVOCADO) OIL 05D - Permanent Waves 1

PERSEA GRATISSIMA (AVOCADO) OIL 05F - Shampoos (non-coloring) 26

PERSEA GRATISSIMA (AVOCADO) OIL 05G - Tonics, Dressings, and Other Hair Grooming Aids 33

PERSEA GRATISSIMA (AVOCADO) OIL 05I - Other Hair Preparations 57

PERSEA GRATISSIMA (AVOCADO) OIL 07A - Blushers (all types) 2

PERSEA GRATISSIMA (AVOCADO) OIL 07C - Foundations 4

PERSEA GRATISSIMA (AVOCADO) OIL 07E - Lipstick 60

PERSEA GRATISSIMA (AVOCADO) OIL 07F - Makeup Bases 23

PERSEA GRATISSIMA (AVOCADO) OIL 07I - Other Makeup Preparations 14

PERSEA GRATISSIMA (AVOCADO) OIL 08A - Basecoats and Undercoats 1

PERSEA GRATISSIMA (AVOCADO) OIL 08B - Cuticle Softeners 2

PERSEA GRATISSIMA (AVOCADO) OIL 08C - Nail Creams and Lotions 1

PERSEA GRATISSIMA (AVOCADO) OIL 08D - Nail Extenders 1

PERSEA GRATISSIMA (AVOCADO) OIL 08F - Nail Polish and Enamel Removers 1

PERSEA GRATISSIMA (AVOCADO) OIL 08G - Other Manicuring Preparations 1

PERSEA GRATISSIMA (AVOCADO) OIL 10A - Bath Soaps and Detergents 30

PERSEA GRATISSIMA (AVOCADO) OIL 10E - Other Personal Cleanliness Products 13

PERSEA GRATISSIMA (AVOCADO) OIL 11A - Aftershave Lotion 2

PERSEA GRATISSIMA (AVOCADO) OIL 11E - Shaving Cream 4

PERSEA GRATISSIMA (AVOCADO) OIL 11F - Shaving Soap 2

PERSEA GRATISSIMA (AVOCADO) OIL 11G - Other Shaving Preparation Products 2

PERSEA GRATISSIMA (AVOCADO) OIL 12A - Cleansing 37

PERSEA GRATISSIMA (AVOCADO) OIL 12B - Depilatories 1

PERSEA GRATISSIMA (AVOCADO) OIL 12C - Face and Neck (exc shave) 35

PERSEA GRATISSIMA (AVOCADO) OIL 12D - Body and Hand (exc shave) 95

PERSEA GRATISSIMA (AVOCADO) OIL 12E - Foot Powders and Sprays 1

PERSEA GRATISSIMA (AVOCADO) OIL 12F - Moisturizing 199

PERSEA GRATISSIMA (AVOCADO) OIL 12G - Night 20

PERSEA GRATISSIMA (AVOCADO) OIL 12H - Paste Masks (mud packs) 14

PERSEA GRATISSIMA (AVOCADO) OIL 12I - Skin Fresheners 2

PERSEA GRATISSIMA (AVOCADO) OIL 12J - Other Skin Care Preps 46

PERSEA GRATISSIMA (AVOCADO) OIL 13A - Suntan Gels, Creams, and Liquids 5

PERSEA GRATISSIMA (AVOCADO) OIL 13B - Indoor Tanning Preparations 8

PERSEA GRATISSIMA (AVOCADO) OIL 13C - Other Suntan Preparations 3

TRITICUM VULGARE (WHEAT) GERM OIL 01A - Baby Shampoos 1

TRITICUM VULGARE (WHEAT) GERM OIL 01B - Baby Lotions, Oils, Powders, and Creams 6

TRITICUM VULGARE (WHEAT) GERM OIL 01C - Other Baby Products 2

TRITICUM VULGARE (WHEAT) GERM OIL 02A - Bath Oils, Tablets, and Salts 1



TRITICUM VULGARE (WHEAT) GERM OIL 02D - Other Bath Preparations 1

TRITICUM VULGARE (WHEAT) GERM OIL 03C - Eye Shadow 1

TRITICUM VULGARE (WHEAT) GERM OIL 03D - Eye Lotion 5

TRITICUM VULGARE (WHEAT) GERM OIL 03E - Eye Makeup Remover 1

TRITICUM VULGARE (WHEAT) GERM OIL 03F - Mascara 3

TRITICUM VULGARE (WHEAT) GERM OIL 03G - Other Eye Makeup Preparations 2

TRITICUM VULGARE (WHEAT) GERM OIL 04E - Other Fragrance Preparation 2

TRITICUM VULGARE (WHEAT) GERM OIL 05A - Hair Conditioner 48

TRITICUM VULGARE (WHEAT) GERM OIL 05B - Hair Spray (aerosol fixatives) 4

TRITICUM VULGARE (WHEAT) GERM OIL 05C - Hair Straighteners 3

TRITICUM VULGARE (WHEAT) GERM OIL 05F - Shampoos (non-coloring) 30

TRITICUM VULGARE (WHEAT) GERM OIL 05G - Tonics, Dressings, and Other Hair Grooming Aids 30

TRITICUM VULGARE (WHEAT) GERM OIL 05H - Wave Sets 1

TRITICUM VULGARE (WHEAT) GERM OIL 05I - Other Hair Preparations 25

TRITICUM VULGARE (WHEAT) GERM OIL 06A - Hair Dyes and Colors (all types requiring caution statements and patch tests)9

TRITICUM VULGARE (WHEAT) GERM OIL 06D - Hair Shampoos (coloring) 1

TRITICUM VULGARE (WHEAT) GERM OIL 06F - Hair Lighteners with Color 3

TRITICUM VULGARE (WHEAT) GERM OIL 06G - Hair Bleaches 6

TRITICUM VULGARE (WHEAT) GERM OIL 06H - Other Hair Coloring Preparation 1

TRITICUM VULGARE (WHEAT) GERM OIL 07C - Foundations 1

TRITICUM VULGARE (WHEAT) GERM OIL 07E - Lipstick 29

TRITICUM VULGARE (WHEAT) GERM OIL 07I - Other Makeup Preparations 5

TRITICUM VULGARE (WHEAT) GERM OIL 08B - Cuticle Softeners 1

TRITICUM VULGARE (WHEAT) GERM OIL 08C - Nail Creams and Lotions 1

TRITICUM VULGARE (WHEAT) GERM OIL 10A - Bath Soaps and Detergents 16

TRITICUM VULGARE (WHEAT) GERM OIL 10E - Other Personal Cleanliness Products 6

TRITICUM VULGARE (WHEAT) GERM OIL 11A - Aftershave Lotion 1

TRITICUM VULGARE (WHEAT) GERM OIL 12A - Cleansing 19

TRITICUM VULGARE (WHEAT) GERM OIL 12C - Face and Neck (exc shave) 42

TRITICUM VULGARE (WHEAT) GERM OIL 12D - Body and Hand (exc shave) 78

TRITICUM VULGARE (WHEAT) GERM OIL 12F - Moisturizing 75

TRITICUM VULGARE (WHEAT) GERM OIL 12G - Night 15

TRITICUM VULGARE (WHEAT) GERM OIL 12H - Paste Masks (mud packs) 7

TRITICUM VULGARE (WHEAT) GERM OIL 12J - Other Skin Care Preps 39

TRITICUM VULGARE (WHEAT) GERM OIL 13A - Suntan Gels, Creams, and Liquids 2

TRITICUM VULGARE (WHEAT) GERM OIL 13B - Indoor Tanning Preparations 1

TRITICUM VULGARE (WHEAT) GERM OIL 13C - Other Suntan Preparations 3


Personal CareProducts CouncilCommitted to Safety,Quality & Innovation

Memorandum

TO: F. Alan Andersen, Ph.D.Director - COSMETIC INGREDIENT REVIEW (CW)

FROM: CIR Science and Support Committee

DATE: May 13, 2010

SUBJECT: Concentration of Use Plant Oils March 2010 Survey

Concentration of Use Vegetable Oil and Hydrogenated Vegetable Oil

Concentration of Use Major Plant Seed Oils March 2010 Survey

Concentration of Use Minor Plant Seed Oils March 2010 Survey

1101 17th Street, N.W., Suite 3O0 Washington, D.C. 20036-4702 202.331.1770 202.331 .1969 (fax) www.personcilcarecouncil.org CIR Panel Book Page 93

Concentration of Use - Vegetable Oil and Hydrogenated Vegetable Oil

Ingredient Product Category Concentration of Use

Vegetable Oil Bath oils, tablets and salts 0002-0.02%

Vegetable Oil Eyebrow pencil 0.02-0.05%

Vegetable Oil Eye shadow 0.01-11%

Vegetable Oil Eye lotion 0.05-2%

Vegetable Oil Mascara 2%

Vegetable Oil Perfumes 0.0005-0.02%

Vegetable Oil Hair conditioners 2%

Vegetable Oil Pennanent waves 0.02%

Vegetable Oil Tonics, dressings and other hair grooming aids 0.07%

Vegetable Oil Other hair preparations (noncoloring) 0.02%

Vegetable Oil Foundations 0.04-5%

Vegetable Oil Lipstick 0.03-11%

Vegetable Oil Other makeup preparations 0.005-0.09%

Vegetable Oil Cuticle softeners 2%

Vegetable Oil Bath soaps and detergents 0.03-2%

Vegetable Oil Skin cleansing (cold creams, cleansing lotions, 0.1%liquids and pads)

Vegetable Oil Depilatories 31%

Vegetable Oil Face and neck creams, lotions and powders 0.3-2%

Vegetable Oil Body and hand creams, lotions and powders 0.2-5%

Vegetable Oil Moisturizing creams, lotions and powders 0.05%

Vegetable Oil Night creams, lotions and powders 0.05-2%

Vegetable Oil Other skin care preparations 0.0005-8%

Vegetable Oil Other suntan preparations 0.03-1%

Hydrogenated Vegetable Oil Other bath preparations 0.5%

Hydrogenated Vegetable Oil Eyebrow pencil 7-31%

Hydrogenated Vegetable Oil Eyeliner 10-49%

Hydrogenated Vegetable Oil Eye shadow 0.4-25%

Hydrogenated Vegetable Oil Eye lotion 0.2-1 1%

Hydrogenated Vegetable Oil Mascara 0.008-8%

Page 1 of 2


Information collected in 2010Table prepared May 12, 2010

Hydrogenated Vegetable Oil Hair conditioners 0.0007%

Hydrogenated Vegetable Oil Shampoos (noncoloring) 0.0005%

Hyclrogenated Vegetable Oil Tonics, dressings and other hair grooming aids 0.09%

Hydrogenated Vegetable Oil Hair dyes and colors (all types requiring 0.0004%caution statement and patch test)

Hydrogenated Vegetable Oil Hair tints 1%

Hydrogenated Vegetable Oil Blushers (all types) 2-6%

Hydrogenated Vegetable Oil Face powders 1%

Hydrogenated Vegetable Oil Foundations 0.2-57%

Hydrogenated Vegetable Oil Lipstick 0.8-60%

Hydrogenated Vegetable Oil Other makeup preparations 0.02-31%

Hydrogenated Vegetable Oil Cuticle softeners 0.2%

Hydrogenated Vegetable Oil Bath soaps and detergents 2%

Hydrogenated Vegetable Oil Other personal cleanliness products 4%

Hydrogenated Vegetable Oil Shaving cream (aerosol, brushless and lather) 0.002%

Hydrogenated Vegetable Oil Skin cleansing (cold creams, cleansing lotions 8%liquids and pads)

Hydrogenated Vegetable Oil Depilatories 6%

Hydrogenated Vegetable Oil Face and neck cream, lotions and powders 3-20%

Hydrogenated Vegetable Oil Body and hand creams, lotions and powders 0.01-14%

Hydrogenated Vegetable Oil Foot powders and sprays 3%

Hydrogenated Vegetable Oil Night creams, lotions and powders 0.0005-0.2%

Hydrogenated Vegetable Oil Paste masks (mud packs) 8%

Hydrogenated Vegetable Oil Other skin care preparations 2-8%

Hydrogenated Vegetable Oil Suntan gels, creams and liquids 3%

Hydrogenated Vegetable Oil Other suntan preparations 12%

Page 2 of 2


Concentration of Use Major Plant Seed Oils March 2010 SurveyBrassica Campestris (Rapeseed) Seed Oil, Brassica Campestris (Rapeseed) Oil Unsaponifiables, Hydrogenated RapeseedOil, Potassium Rapessedate, Rapeseed Acid, Sodium Rapseedate, Canola Oil, Canola Oil Unsaponifables, Hydrogenated

Canola Oil, Glycine Soja (Soybean) Oil, Glycine Soja (Soybean) Oil Unsaponifiables, Hydrogenated Soybean Oil, SoyAcid, Potassium Sovate, Sodium Soyate. Hetianthus Annuus (Sunflower) Seed Oil, Helianthus Annuns (Sunflower) Seed

Oil Unsaponifiables, Hydrogenated Sunflower Seed Oil, Sunflower Seed Acid, Olea Europaea (Olive) Fruit Oil, OleaEuropaea (Olive) Oil Unsaponifiables, Hydrogenated Olive Oil, 1-lydrogenated Olive Oil Unsaponifiables, Olive Acid, Olea

Europea (Olive) Husk Oil, Olea Europeae (Olive) Oil Unsaponifiables, Potassium Olivate, Sodium Olivate*

Ingredient Product Category Concentration of Use

Brassica Campestris (Rapeseed) Oil Shampoos (noncoloring) 0.1%

Brassica Campestris (Rapeseed) Oil Lipstick 9%

Brassica Campestris (Rapeseed) Oil Preshave lotions (all types) 1%

Brassica Campestris (Rapeseed) Oil Skin cleansing (cold creams, cleansing lotions, 0.01-10%liquids and pads)

Brassica Campestris (Rapeseed) Oil Face and neck creams, lotions, and powders 2-17%

Brassica Campestris (Rapeseed) Oil Body and hand creams, lotions, and powders 0.0 1-9%

Brassica Campestris (Rapeseed) Oil Moisturizing crams, lotions and powders 3%

Brassica Campestris (Rapeseed) Oil Night creams, lotions and powders 3%

Brassica Campestris (Rapeseed) Oil Paste masks (mud packs) 1%

Brassica Campestris (Rapeseed) Oil Other skin care preparations 0.07%

Brassica Campestris (Rapeseed) Oil Other suntan preparations 0,007%

Hydrogenated Rapeseed Oil Mascara 2%

Hydrogenated Rapeseed Oil Foundations 0.3%

Hydrogenated Rapeseed Oil Skin cleansing (cold creams, cleansing lotions, 4%liquids and pads)

Hydrogenated Rapeseed Oil Other skin care preparations 0.8%

Canola Oil Bath oils, tablets, and salts 1-33%

Canola Oil Eye shadow 0.03%

Canola Oil Eye lotion 0.002%

Canola Oil Colognes and toilet waters 0.02%

Canola Oil Perfumes 17%

Canola Oil Other fragrance preparations 0.0002%

Canola Oil Hair conditioners 0.9-24%

Canola Oil Hair sprays (aerosol fixatives) 0.006%

Canola Oil Shampoos (noncoloring) 0.06%

Canola Oil Tonics, dressings, and other hair grooming aids 0.1-1 1%

Page 1 of 9


Canola Oil Foundations 0.02%

Canola Oil Lipstick 0.3-70%

Canola Oil Nail clealus and lutiuns

Canola Oil Bath soaps and detergents 02-1%

Canola Oil Other personal cleanliness products 0.02%

Canola Oil Skin cleansing (cold creams, cleansing lotions, 2%liquids and pads)

Canola Oil Depilatories 002-0.06%

Canola Oil Face and neck creams, lotions, and powders 1-5%

Canola Oil Body and hand creams, lotions, and powders 28-73%

Canola Oil Paste masks (mud packs) 3%

Canola Oil Other skin care preparations 0.03-5%

Canola Oil Other suntan preparations 0.09%

Canola Oil Unsaponifiables Hair conditioners 0.00 1%

Canola Oil Unsaponifiables Shampoos (noncoloring) 0.001%

Glycine Soja (Soybean) Oil Baby lotions, oils, powders and creams 2%

Glycine Soja (Soybean) Oil Bath oils, tablets, and salts 0,1-78%

Glycine Soja (Soybean) Oil Eyebrow pencil 0.1-1%

Glycine Soja (Soybean) Oil Eyeliner 0.1-1%

Glycine Soja (Soybean) Oil Eye shadow 0.005-0.8%

Glycine Soja (Soybean) Oil Eye lotion 0.2-2%

Glycine Soja (Soybean) Oil Mascara 0.04 - 2%

Glycine Soja (Soybean) Oil Perfumes 0.03-0.5%

Glycine Soja (Soybean) Oil Other fragrance preparations 0.04%

Glycine Soja (Soybean) Oil Hair conditioners 0.0002-30%

Glycine Soja (Soybean) Oil Permanent waves 95%

Glycine Soja (Soybean) Oil Rinses (noncoloring) 0.02%

Glycine Soja (Soybean) Oil Shampoos (noncoloring) 0.0 1-0.2%

Glycine Soja (Soybean) Oil Tonics, dressings, and other hair grooming aids 0.2-66%

Glycine Soja (Soybean) Oil Blushers (all types) 0.005-0.7%

Glycine Soja (Soybean) Oil Face powders 0.005%

Glycine Soja (Soybean) Oil Foundations 0.0 1-1%

Page 2 of 9


Glycine Soja (Soybean) Oil Leg and body paints 0.3%

Glycine Soja (Soybean) Oil Lipstick 0.06-4%

Glycine Soja (S%heaa) Oil NIakeup has 0.0

Glycine Soja (Soybean) Oil Nail creams and lotions 2-95%

Glycine Soja (Soybean) Oil Nail polish and enamel 0.02%

Glycine Soja (Soybean) Oil Nail polish and enamel removers 0.02%

Glycine Soja (Soybean) Oil Bath soaps and detergents 0.0 1-52%

Glycine Soja (Soybean) Oil Deodorants (underarm) 0.0 1-0.5%

Glycine Soja (Soybean) Oil Preshave lotions (all types) 8%

Glycine Soja (Soybean) Oil Other shaving preparations 93%

Glycine Soja (Soybean) Oil Skin cleansing (cold creams, cleansing lotions, 0.2-9%liquids and pads)

Glycine Soja (Soybean) Oil Depilatories 0.5%

Glycine Soja (Soybean) Oil Face and neck creams, lotions, and powders 0.0005-4%

Glycine Soja (Soybean) Oil Body and hand creams, lotions, and powders 0.1-75%

Glycine Soja (Soybean) Oil Foot powders and sprays 0.05%

Glycine Soja (Soybean) Oil Moisturizing creams, lotions and powders 0.1-94%

Glycine Soja (Soybean) Oil Night creams, lotions and powders 0.008-4%

Glycine Soja (Soybean) Oil Paste masks (mud packs) 0.008-1%

Glycine Soja (Soybean) Oil Other skin care preparations 0.04-49%

Glycine Soja (Soybean) Oil Suntan gels, creams, and liquids 1%

Glycine Soja (Soybean) Oil Indoor tanning preparations 1%

Glycine Soja (Soybean) Oil Other suntan preparations 0.2-0.3%

Glycine Soja (Soybean) Oil Foundations 0.03-0.1%Unsaponifiables

Glycine Soja (Soybean) Oil Face and neck creams, lotions, and powders 0,2%Unsaponifiables

Glycine Soja (Soybean) Oil Moisturizing creams, lotions and powders 0.0001%Unsaponifiables

Hydrogenated Soybean Oil Bath oils, tablets and salts 42%

Hydrogenated Soybean Oil Bubble baths 5%

Hydrogenated Soybean Oil Eyebrow pencil 7%

Hydrogenated Soybean Oil Eyeliner 5%

Page 3 of 9


Hydrogenated Soybean Oil Eye shadow 0.03-2%

Hydrogenated Soybean Oil Hair conditioners 0.1%

HydrogcLttcl Soybcati Oil Bliislicrs (all ps) I 1

Hydrogenated Soybean Oil Face powders 0.07%

Hydrogenated Soybean Oil Foundations 0.09-15%

Hydrogenated Soybean Oil Lipstick 0.1-39%

Hydrogenated Soybean Oil Makeup bases 4%

Hydrogenated Soybean Oil Other makeup preparations 0.01%

Hydrogenated Soybean Oil Basecoats and undercoats (manicuring preparations) 0.001%

Hydrogenated Soybean Oil Cuticle softeners 0.05-2%

Hydrogenated Soybean Oil Nail creams and lotions 25%

Hydrogenated Soybean Oil Nail polish and enamel 0.00 1-2%

Hydrogenated Soybean Oil Bath soaps and detergents 0.05%

Hydrogenated Soybean Oil Other personal cleanliness products 6%

Hydrogenated Soybean Oil Skin cleansing (cold creams, cleansing lotions, 0.2-15%liquids and pads)

Hydrogenated Soybean Oil Depilatories 0.1%

Hydrogenated Soybean Oil Face and neck creams, lotions, and powders 2%

Hydrogenated Soybean Oil Body and hand creams, lotions, and powders 0.1-5%

Hydrogenated Soybean Oil Moisturizing creams, lotions and powders 0.4-5%

Hydrogenated Soybean Oil Night creams, lotions and powders 0.5-0.8%

Hydrogenated Soybean Oil Paste masks (mud packs) 7%

Hydrogenated Soybean Oil Other skin care preparations 4-21%

Hydrogenated Soybean Oil Indoor tanning preparations 1-2%

Hydrogenated Soybean Oil Other suntan preparations 0.5%

Helianthus Annuus (Sunflower) Seed Oil Other baby products 0.2%

Helianthus Annuus (Sunflower) Seed Oil Bath oils, tablets, and salts 0.05-75%

Helianthus Annuus (Sunflower) Seed Oil Bubble baths 0.2%

Helianthus Annuus (Sunflower) Seed Oil Eyebrow pencil 0.1%

Helianthus Annuus (Sunflower) Seed Oil Eyeliner 0.01-19%

Helianthus Annuus (Sunflower) Seed Oil Eye Shadow 0.002-0.3%

Helianthus Annuus (Sunflower) Seed Oil Eye lotion 0.0 1-5%

Page 4 of 9


Helianthus Annuus (Sunflower) Seed Oil Eye makeup remover 0.0005-2%

Helianthus Annuus (Sunflower) Seed Oil Mascara 0.1%

1—lelianiluis Aiinuns (Suniio\ver) Seed Oil Colngnns and oi Lt waters 0.027

Helianthus Annuus (Sunflower) Seed Oil Perfumes 0.03%

Helianthus Annuus (Sunflower) Seed Oil Other fragrance preparations 0.1-85%

Helianthus Annuus (Sunflower) Seed Oil Hair conditioners 0.000007-92%

Helianthus Annuus (Sunflower) Seed Oil Hair sprays (aerosol fixatives) 0.06-0.07%

Helianthus Annuus (Sunflower) Seed Oil Rinses (noncoloring) 0.1%

Helianthus Annuus (Sunflower) Seed Oil Shampoos (noncoloring) 0.00007- 0.3%

Helianthus Annuus (Sunflower) Seed Oil Tonics, dressings, and other hair grooming aids 0.1-83%

Helianthus Annuus (Sunflower) Seed Oil Other hair preparations (noncoloring) 0.3-15%

Helianthus Annuus (Sunflower) Seed Oil Hair dyes and colors 0.8%

Helianthus Annuus (Sunflower) Seed Oil Hair tints 20-35%

Helianthus Annuus (Sunflower) Seed Oil Hair bleaches 0.03%

Helianthus Annuus (Sunflower) Seed Oil Other hair coloring preparations 2%

Helianthus Annuus (Sunflower) Seed Oil Blushers (all types) 0.1-10%

Helianthus Annuus (Sunflower) Seed Oil Face powders 0.0 1-0.5%

Helianthus Annuus (Sunflower) Seed Oil Foundations 0.1-16%

Helianthus Annuus (Sunflower) Seed Oil Lipstick 0.08-41%

Helianthus Annuus (Sunflower) Seed Oil Makeup bases 0.1%

Helianthus Annuus (Sunflower) Seed Oil Other makeup preparations 2%

Helianthus Annuus (Sunflower) Seed Oil Cuticle softeners 30%

Helianthus Annuus (Sunflower) Seed Oil Nail polish and enamel removers 0.05%

Helianthus Annuus (Sunflower) Seed Oil Other manicuring preparations 0.4%

Helianthus Annuus (Sunflower) Seed Oil Bath soaps and detergents 0.003-10%

Helianthus Annuus (Sunflower) Seed Oil Deodorants (underarm) 0.0003-4%

Helianthus Annuus (Sunflower) Seed Oil Other personal cleanliness products 0.02-6%

Helianthus Annuus (Sunflower) Seed Oil Preshave lotions (all types) 0.2%

Helianthus Annuus (Sunflower) Seed Oil Shaving cream (aerosol, brushless, and lather) 0.1-0.5%

Helianthus Annuus (Sunflower) Seed Oil Skin cleansing (cold creams, cleansing lotions, 0.03-35%liquids and pads)

Helianthus Annuus (Sunflower) Seed Oil Depilatories 0.07-2%

Page 5 of 9


Helianthus Annuus (Sunflower) Seed Oil Face and neck creams, lotions, and powders 0.0 1-28%

Helianthus Annuus (Sunflower) Seed Oil Body and hand creams, lotions, and powders 0.00 1-96%

1-lelianthus .•\niuus (Sunflower) Seed OP Bud’ and hand sprays 00002—I %

Helianthus Annuus (Sunflower) Seed Oil Moisturizing creams, lotions and powders 0.1-3%

Helianthus Annuus (Sunflower) Seed Oil Night creams, lotions and powders 0.05-48%

Helianthus Annuus (Sunflower) Seed Oil Paste masks (mud packs) 0.3-16%

Helianthus Annuus (Sunflower) Seed Oil Skin fresheners 0.1%

Helianthus Annuus (Sunflower) Seed Oil Other skin care preparations 0.02-80%

Helianthus Annuus (Sunflower) Seed Oil Suntan gels, creams, and liquids 1-23%

Helianthus Annuus (Sunflower) Seed Oil Indoor tanning preparations 0.002%

Helianthus Annuus (Sunflower) Seed Oil Other suntan preparations 0.1%

Helianthus Annuus (Sunflower) Seed Eyeliner 0.02%Unsaponifiables

Helianthus Annuus (Sunflower) Seed Blushers (all types) 0.1%Unsaponifiables

Helianthus Annuus (Sunflower) Seed Other personal cleanliness products 0.02%Unsaponifiables

Helianthus Annuus (Sunflower) Seed Face and neck creams, lotions, and powders 2%Unsaponifiables

Helianthus Annuus (Sunflower) Seed Body and hand creams, lotions, and powders 0.02%Unsaponifiables

Helianthus Annuus (Sunflower) Seed Night creams, lotions and powders 0.01-2%Unsaponifiables

Helianthus Annuus (Sunflower) Seed Other skin care preparations 0.005%Unsaponifiables

Hydrogenated Sunflower Seed Oil Eyeliner 7%

Hydrogenated Sunflower Seed Oil Hair tints 15-35%

Hydrogenated Sunflower Seed Oil Lipstick 6%

Hydrogenated Sunflower Seed Oil Skin cleansing (cold creams, cleansing lotions, 15-35%liquids and pads)

Olea Europaea (Olive) Fruit Oil Baby lotions, oils, powders and creams 0.2%

Olea Europaea (Olive) Fruit Oil Bath oils, tablets, and salts 2%

Olea Europaea (Olive) Fruit Oil Bubble baths 0.9%

Olea Europaea (Olive) Fruit Oil Other bath preparations 17%

Page 6 of 9


Olea Europaea (Olive) Fruit Oil Eyeliner 0.1-17%

Olea Europaea (Olive) Fruit Oil Eye shadow 0.1-2%

Olca Eur parI (Olive) Fruit Oil E. lotion 1-3%

Olea Europaea (Olive) Frut Oil Eye makeup remover 0.0 1-10%

Olea Europaea (Olive) Fruit Oil Mascara 0.004-0.8%

Olea Europaea (Olive) Fruit Oil Perfumes 0.2-5%

Olea Europaea (Olive) Fruit Oil Hair conditioners 0.03-94%

Olea Europaea (Olive) Fruit Oil Hair sprays (aerosol fixatives) 3%

Olea Europaea (Olive) Fruit Oil Hair straighteners 0.01-0.5%

Olea Europaea (Olive) Fruit Oil Rinses (noncoloring) 0.01%

Olea Europaea (Olive) Fruit Oil Shampoos (noncoloring) 0.006-0.5%

Olea Europaea (Olive) Fruit Oil Tonics, dressings, arid other hair grooming aids 0.01-15%

Olea Europaea (Olive) Fruit Oil Other hair preparations (noncoloring) 1%

Olea Europaea (Olive) Fruit Oil Hair dyes and colors (all types requiring caution 0.2%statement and patch test)

Olea Europaea (Olive) Fruit Oil Hair bleaches 0.2%

Olea Europaea (Olive) Fruit Oil Other hair coloring preparations 0.5%

Olea Europaea (Olive) Fruit Oil Blushers (all types) 0.1-26%

Olea Europaea (Olive) Fruit Oil Face powders 0.08-2%

Olea Europaea (Olive) Fruit Oil Foundations 0.1-44%

Olea Europaea (Olive) Fruit Oil Leg and body paints 32%

Olea Europaea (Olive) Fruit Oil Lipstick 0.7-26%

Olea Europaea (Olive) Fruit Oil Makeup bases 49%

Olea Europaea (Olive) Fruit Oil Rouges 0.5%

Olea Europaea (Olive) Fruit Oil Other makeup preparations 0.4%

Olea Europaea (Olive) Fruit Oil Basecoats and undercoats (manicuring preparations) 0.00 1%

Olea Europaea (Olive) Fruit Oil Cuticle softeners 1-2%

Olea Europaea (Olive) Fruit Oil Nail creams and lotions 3%

Olea Europaea (Olive) Fruit Oil Other manicuring preparations 40%

Olea Europaea (Olive) Fruit Oil Bath soaps and detergents 0.0005-3%

Olea Europaea (Olive) Fruit Oil Deodorants (underarm) 0.02-0.1%

Olea Europaea (Olive) Fruit Oil Other personal cleanliness products 0.00 1-0.05%

Page 7 of 9


Olea Europaea (Olive) Fruit Oil Aftershave lotions 0.5%

Olea Europaea (Olive) Fruit Oil Shaving cream (aerosol, brushless, and lather) 0.007-0.1%

QIL’a F ropnca (Olive) Fruit Oil Skin cL’nns ing (cold creams. clennsing lotions. 0.01—10%liquids and pads)

Olea Europaea (Olive) Fruit Oil Depilatories 0.1%

Olea Europaea (Olive) Fruit Oil Face and neck creams, lotions, and powders 0.03-50%

Olea Europaea (Olive) Fruit Oil Body and hand creams, lotions, and powders 0.03-100%

Olea Europaea (Olive) Fruit Oil Foot powders and sprays 3%

Olea Europaea (Olive) Fruit Oil Moisturizing creams, lotions and powders 0.05-3%

Olea Europaea (Olive) Fruit Oil Night creams, lotions and powders 0.005-1%

Olea Europaea (Olive) Fruit Oil Paste masks (mud packs) 0.0005-3%

Olea Europaea (Olive) Fruit Oil Other skin care preparations 0.05-33%

Olea Europaea (Olive) Fruit Oil Suntan gels, creams, and liquids 0.1%

Olea Europaea (Olive) Fnut Oil Indoor tanning preparations 1%

Olea Europaea (Olive) Fruit Oil Other suntan preparations 20%

Olea Europaea (Olive) Oil Unsaponifiables Baby lotions, oils, powders and creams 0.04%

Olea Europaea (Olive) Oil Unsaponifiables Eye shadow 0.02-0.4%

Olea Europaea (Olive) Oil Unsaponifiables Eye lotion 0.3%

Olea Europaea (Olive) Oil Unsaponifiables Mascara 0.2%

Olea Europaea (Olive) Oil Unsaponifiables Other fragrance preparations 3%

Olea Europaea (Olive) Oil Unsaponifiables Hair conditioners 0.07-0.3%

Olea Europaea (Olive) Oil Unsaponifiables Shampoos (noncoloring) 0.2%

Olea Europaea (Olive) Oil Unsaponifiables Tonics, dressings, and other hair grooming aids 0.02%

Olea Europaea (Olive) Oil Unsaponifiables Foundations 2%

Olea Europaea (Olive) Oil Unsaponifiables Lipstick 0.08%

Olea Europaea (Olive) Oil Unsaponifiables Face and neck creams, lotions, and powders 0.3%

Olea Europaea (Olive) Oil Unsaponifiables Body and hand creams, lotions, and powders 0.01-0.04%

Olea Europaea (Olive) Oil Unsaponiflables Moisturizing creams, lotions and powders 0.0001%

Hydrogenated Olive Oil Baby lotions, oils, powders and creams 0.4%

Hydrogenated Olive Oil Eye Shadow 0.1-3%

Hydrogenated Olive Oil Eye lotion 0.1%

Hydrogenated Olive Oil Mascara 2%

Page 8 of 9


Hydrogenated Olive Oil Hair conditioners 0.01%

Hydrogenated Olive Oil Shampoos (noncoloring) 0.1%

tld: ‘genated Olive Oil Face po\\ders 12%

Hydrogenated Olive Oil Foundations 0.1-7%

Hydrogenated Olive Oil Lipstick 0.1-12%

Hydrogenated Olive Oil Nail creams and lotions 0.1%

Hydrogenated Olive Oil Bath soaps and detergents 0.0005%

Hydrogenated Olive Oil Face and neck creams, lotions, and powders 1-2%

Hydrogenated Olive Oil Body and hand creams, lotions, and powders 0.1-1%

Hydrogenated Olive Oil Moisturizing creams, lotions and powders 0.2%

Hydrogenated Olive Oil Night creams, lotions and powders 0.1-0.5%

Hydrogenated Olive Oil Paste masks (mud packs) 0.1%

Hydrogenated Olive Oil Other skin care preparations 1%

Hydrogenated Olive Oil Indoor tanning preparations 0.1%

Hydrogenated Olive Oil Other suntan preparations 0.1%

Hydrogenated Olive Oil Unsaponifiables Eye shadow 2%

Hydrogenated Olive Oil Unsaponifiables Eye lotion 0.3%

Hydrogenated Olive Oil Unsaponifiables Foundations 0.05-3%

Hydrogenated Olive Oil Unsaponifiables Skin cleansing (cold creams, cleansing lotions, 5%liquids and pads)

Hydrogenated Olive Oil Unsaponifiables Face and neck creams, lotions, and powders 3%

Hydrogenated Olive Oil Unsaponifiables Body and hand creams, lotions, and powders 2%

Hydrogenated Olive Oil Unsaponifiables Night creams, lotions and powders 2%

Sodium Olivate Bath soaps and detergents 4-18%

*Ingredients included in the title of the table, but not found in the table were included in the survey, but no uses were reportedInformation collected in 2010Table prepared May 13, 2010

The following ingredients will be included in a later concentration of use survey: Hydrogenated Safflower Oil, PotassiumSafflowerate, Safflower Acid, Sodium Safflowerate, Elaeis Guineensis (Palm)Oil, Elaeis Guineensis (Palm) Kernel Oil,Hydrogenated Palm Oil, Hydrogenated Palm Kernel Oil, Palm Kernel Acid, Elaeis Guineensis (Palm) Butter, Elaeis OleiferaKernel Oil, Elaies (Palm) Oil, Palm Acid, Hydrogenated Palm Acid, Potassium Palmate, Potassium Hydrogentaed Pamlate,Potassium Hydrogenated Palmate, Potassium Palm Kernelate, Sodium Hydrogenated Palmate, Sodium Palmate, Sodium PalmKernelate, Gossypium Herbaceum (Cotton) Seed Oil, Cottonseed Acid, Hydrogenated Cottonseed Oil, Oryza Sativa (Rice) BranOil, Oryza Sativa (Rice) Germ Oil, Rice Bran Acid, Hydrogenated Rice Bran Oil, Oryza Sativa (Rice) Seed Oil, SesamumIndicum (Sesame) Seed Butter

Page 9 of 9


Concentration of Use Minor Plant Seed Oils Mach 2010 SurveyActinidia Chinensis (Kiwi) Seed Oil, Adansonia Digitata Oil, Adansonia Digitata Seed Oil, Hydrogenated Adansonia

Digitata Seed Oil, Amaranthus Hypochondriacus Seed Oil, Arctium Lappa Seed Oil, Argania Spinosa Kernel Oil,Hydrogenated Argania Spinosa Kernel Oil, Astrocarym Murumuru Seed Butter, Sodium Astrocaryum Murumuruate,

Avena Sativa (Oat) Kernel Oil, Borago Officinalis Seed Oil, Brassica Oleracea Italica (Broccoli) Seed Oil, Camelina SativaSeed Oil, Hydrogenated Camelina Sativa Seed Oil, Camellia Oleifera Seed Oil, Hydrogenated Camellia Oleifera Seed Oil,

Camellia Sinensis Seed Oil, Carica Papaya Seed Oil, Caryocar Brasiliense Fruit Oil, Chenopodium Quinoa Seed Oil,Citrullus Lanatus (Watermelon) Seed Oil, Citrus Aurantifolia (Lime) Seed Oil, Hydrogenated Lime Seed Oil,

Hydrogenated Lime Seed Oil Unsaponifiables, Citrus Aurantium Dulcis (Orange) Seed Oil, Citrus Aurantium Dulcis(Orange) Seed Oil Unsaponifiables, Hydrogenated Orange Seed Oil, Hydrogenated Orange Seed Oil Unsaponifiables,

Citrus Grandis (Grapefruit) Seed Oil, Citrus Grandis (Grapefruit) Seed Oil Unsaponifiables, Citrus Paradisi (Grapefruit)Seed Oil, Hydrogenated Grapefruit Seed Oil, Hydrogenated Grapefruit Seed Oil Unsaponifiables, Citrus Limon (Lemon)Seed Oil, Coix Lacryma-Jobi (Job’s Tears) Seed Oil, Cucumis Sativus (Cucumber) Seed Oil, Cucurbita Fepo (Pumpkin)

Seed Oil, Hydrogenated Pumpkin Seed Oil, Cynara Cardunculus Seed Oil, Euterpe Oleracea Fruit Oil, Fragaria Ananassa(Strawberry) Seed Oil, Fragaria Chiloensis (Strawberry) Seed Oil, Fragaria Vesca (Strawberry) Seed Oil, Fragaria

Virginiana (Strawberry) Seed Oil, Guizotia Abyssinica Seed Oil, Irvingia Gabonensis Kernel Butter, Limnanthes Alba(Meadowfoam) Seed Oil, Hydrogenated Meadowfoam Seed Oil, Linum Usitatissimum (Linseed) Oil, Linseed Acid,

Mangifera Indica (Mango) Seed Oil, Mangifera Indica (Mango) Seed Butter, Sodium Mangoseedate, Moringa OleiferaSeed Oil, Moringa Pterygosperma Seed Oil, Oenothera Biennis (Evening Primrose) Oil, Hydrogenated Evening PrimroseOil, Orbignya Oleifera Seed Oil, Babassu Acid, Potassium Babassuate, Sodium Babassuate, Perilla Ocymoides Seed Oil,

Prunus Armeniaca (Apricot) Kernel Oil, Hydrogenated Apricot Kernel Oil, Hydrogenated Apricot Kernel OilUnsaponifiables, Prunus Armeniaca (Apricot) Kernel Oil Unsaponifiables, Prunus Avium (Sweet Cherry) Seed Oil,

Prunus Domestica Seed Oil, Prunus Persica (Peach) Kernel Oil, Hydrogenated Peach Kernel Oil, Pyrus Malus (Apple)Seed Oil, Ribes Nigrum (Black Currant) Seed Oil, Hydrogenated Black Currant Seed Oil, Ribes Rubrum (Currant) Seed

Oil, Rubus Idaeus (Raspberry) Seed Oil, Hydrogenated Raspberry Seed Oil, Sclerocarya Birrea Seed Oil, SilybumMarianum Seed Oil, Solanum Lycopersicum (Tomato) Seed Oil, Solanum Lycopersicum (Tomato) Fruit Oil, Theobroma

Cacao (Cocoa) Seed Butter, Sodium Cocoa Butterate, Theobroma Grandiflorum Seed Butter, Sodium TheobromoaGrandiflorum Seedate, Torreya Nucifera Seed Oil, Vaccinum Macrocarpon (Cranberry) Seed Oil, Hydrogenated

Cranberry Seed Oil, Vitis Vinifera (Grape) Seed Oil, Sodium Grapeseedate, Hydrogenated Grapeseed Oil*

Ingredient Product Category Concentrationof Use

Actinidia Chinensis (Kiwi) Seed Oil Hair conditioners 0.1%

Actinidia Chinensis (Kiwi) Seed Oil Shampoos (noncoloring) 0.1%

Adansonia Digitata Oil Lipstick 0.01%

Argania Spinosa Kernel Oil Bath oils, tablets, and salts 0.05%

Argania Spinosa Kernel Oil Eyebrow pencil 0.1%

Argania Spinosa Kernel Oil Eyeliner 0.1%

Argania Spinosa Kernel Oil Eye shadow 0.2%

Argania Spinosa Kernel Oil Eye lotion 1%

Argania Spinosa Kernel Oil Mascara 0.1%

Argania Spinosa Kernel Oil Hair conditioners 1%

Argania Spinosa Kernel Oil Hair sprays (aerosol fixatives) 0.0 1%

Argania Spiriosa Kernel Oil Shampoos (noncoloring) 0.1%

Argania Spinosa Kernel Oil Hair dyes and colors (all types requiring caution statement 0.1%and patch test)

Page 1 of 15


Argania Spinosa Kernel Oil Other hair coloring preparations 0.07%

Argariia Spinosa Kernel Oil Blushers (all types) 0.1%

Argania Spinosa Kernel Oil Lipstick 0.1-1%

Argania Spinosa Kernel Oil Nail polish and enamel 0.001-0.1%

Argania Spinosa Kernel Oil Bath soaps and detergents 0.00 1-2%

Argania Spinosa Kernel Oil Deodorants (underarm) 0.001%

Argania Spinosa Kernel Oil Other personal cleanliness products 0.5%

Argania Spinosa Kernel Oil Aftershave lotions 0.005%

Argania Spinosa Kernel Oil Skin cleansing (cold creams, cleansing lotions, liquids and 0.002%pads)

Argania Spinosa Kernel Oil Face and neck creams, lotions, and powders 0.5-3%

Argania Spinosa Kernel Oil Body and hand creams, lotions, and powders 4-10%

Argania Spinosa Kernel Oil Moisturizing creams, lotions and powders 0.04%

Argania Spinosa Kernel Oil Night creams, lotions and powders 0.04-0.1%

Argania Spinosa Kernel Oil Other skin care preparations 2-3%

Astrocaryum Murumuru Seed Butter Eyeliner 0.06%

Astrocaryum Murumum Seed Butter Eye shadow 0.2%

Astrocaryum Murumuru Seed Butter Eye lotion 0.5%

Astrocaryum Murumuru Seed Butter Hair conditioners 0.00 1-0.2%

Astrocaryum Murumuru Seed Butter Shampoos (noncoloring) 0.09%

Astrocaryum Murumuru Seed Butter Tonics, dressings, and other hair grooming aids 0.2%

Astrocaryum Murumuru Seed Butter Foundations 1%

Astrocaryum Murumuru Seed Butter Lipstick 1-7%

Astrocaryum Murumuru Seed Butter Other makeup preparations 0.001%

Astrocaryum Murumuru Seed Butter Face and neck creams, lotions, and powders 1%

Astrocaryum Murumuru Seed Butter Body and hand creams, lotions, and powders 0.1-0.2%

Astrocaryum Murumuru Seed Butter Other skin care preparations 0.2%

Astrocaryum Murumuru Seed Butter Indoor tanning preparations 0.1%

Astrocaryum Murumuru Seed Butter Other suntan preparations 0.2%

Sodium Astrocaryum Murumuruate Bath soaps and detergents 0.002%

Sodium Astrocaryum Murumuruate Other shaving preparations products 0.005%

Sodium Astrocaryum Murumuruate Skin cleansing (cold creams, cleansing lotions, liquids and 0.002%pads)

Page2of 15


Avena Sative (Oat) Kernel Oil Baby lotions, oils, powders and creams 0.1%

Avena Sative (Oat) Kernel Oil Other baby products 0.1%

Avena Sative (Oat) Kernel Oil Eye lotion 0.2%

Avena Sative (Oat) Kernel Oil Shampoos (noncoloring) 0.1%

Avena Sative (Oat) Kernel Oil Lipstick 2%

Avena Sative (Oat) Kernel Oil Bath soaps and detergents 0.01-0.1%

Avena Sative (Oat) Kernel Oil Face and neck creams, lotions, and powders 0.5%

Avena Sative (Oat) Kernel Oil Body and hand crams, lotions, and powders 0.1-3%

Avena Sative (Oat) Kernel Oil Moisturizing creams, lotions and powders 0.1%

Avena Sative (Oat) Kernel Oil Night creams, lotions and powders 0.1-0.5%

Borago Officinalis Seed Oil Eye lotion 0.001-0.5%

Borago Officinalis Seed Oil Tonics, dressings and other hair grooming aids 0.1%

Borago Officinalis Seed Oil Lipstick 0.0 1%

Borago Officinalis Seed Oil Bath soaps and detergents 0.00 1%

Borago Officinalis Seed Oil Other personal cleanliness products 0.01%

Borago Officinalis Seed Oil Preshave lotions (all types) 0.04%

Borago Officinalis Seed Oil Shaving cream (aerosol, brushless, and lather) 0.5%

Borago Officinalis Seed Oil Skin cleansing (cold creams, cleansing lotions, liquids and 0.1%pads)

Borago Officinalis Seed Oil Face and neck creams, lotions and powders 1%

Borago Officinalis Seed Oil Body and hand crams, lotions, and powders 0.05-1%

Borago Officinalis Seed Oil Body and hand sprays 0.1%

Borago Officinalis Seed Oil Moisturizing creams, lotions and powders 1%

Borago Officinalis Seed Oil Night creams, lotions and powders 0.5%

Borago Officinalis Seed Oil Other skin care preparations 0.5%

Borago Officinalis Seed Oil Indoor tanning preparations 0.5%

Brassica Oleracea Italica (Broccoli) Seed Hair conditioners 0.5%Oil

Brassica Oleracea Italica (Broccoli) Seed Shampoos (noncoloring) 0.00 1%Oil

Brassica Oleracea Italica (Broccoli) Seed Tonics, dressings, and other hair grooming aids 3%Oil

Camelina Sativa Seed Oil Eye lotion 0.05%

Camelina Sativa Seed Oil Hair conditioners 1%

Page 3 of 15


Camelina Sativa Seed Oil Lipstick 0.05-0.5%

Camelina Sativa Seed Oil Skin Cleansing (cold creams, cleansing lotions, liquids 0.002%and pads)

Camelina Sativa Seed Oil Face and neck creams, lotions, and powders 0.05-1%

Camelina Sativa Seed Oil Body and hand crams, lotions, and powders 0.1-0.9%

Camelina Sativa Seed Oil Moisturizing creams, lotions and powders 0.04%

Camelina Sativa Seed Oil Night creams, lotions and powders 0.04%

Camellia Oleifera Seed Oil Bath oils, tablets, and salts 0.05%

Camellia Oleifera Seed Oil Eye lotions 2%

Camellia Oleifera Seed Oil Tonics, dressings, and other hair grooming aids 2%

Camellia Oleifera Seed Oil Blushers (all types) 1%

Camellia Oleifera Seed Oil Lipstick 3%

Camellia Oleifera Seed Oil Bath soaps and detergents 0.01-0.1%

Camellia Oleifera Seed Oil Skin Cleansing (cold creams, cleansing lotions, liquids 0.003%and pads)

Camellia Oleifera Seed Oil Body and hand crams, lotions, and powders 0.0 1-1%

Camellia Oleifera Seed Oil Moisturizing creams, lotions and powders 0.08%

Camellia Oleifera Seed Oil Night creams, lotions and powders 0.08%

Camellia Oleifera Seed Oil Other suntan preparations 0.01%

Camellia Sinensis Seed Oil Shampoos (noncoloring) 0.1%

Camellia Sinensis Seed Oil Lipstick 0.1%

Camellia Sinensis Seed Oil Bath soaps and detergents 0.1%

Camellia Sinensis Seed Oil Deodorants (underarm) 0.1%

Camellia Sinensis Seed Oil Body and hand crams, lotions, and powders 0.1%

Camellia Sinensis Seed Oil Moisturizing creams, lotions and powders 0.1%

Camellia Sinensis Seed Oil Night creams, lotions and powders 0.1%

Carica Papaya Seed Oil Moisturizing creams, lotions and powders 0.1%

Carica Papaya Seed Oil Night creams, lotions and powders 0.1%

Caryocar Brasilinese Fruit Oil Lipstick 0.2%

Caryocar Brasilinese Fruit Oil Skin Cleansing (cold creams, cleansing lotions, liquids 0.0005%and pads)

Chenopodium Quinoa Seed Oil Hair rinses (coloring) 0.3%

Citrullus Lanatus (Watermelon) Seed Oil Face and neck creams, lotions, and powders 2%

Page4of 15


Citrus Grandis (Grapefruit) Seed Oil Hair conditioners 0.1%

Citrus Grandis (Grapefruit) Seed Oil Shampoos (noncoloring) 0.1%

Citrus Grandis (Grapefruit) Seed Oil Dentifrices (aerosol, liquid, pastes and powders) 0.1%

Citrus Grandis (Grapefruit) Seed Oil Mouthwashes and breath fresheners (liquids and sprays) 0.1%

Citrus Grandis (Grapefruit) Seed Oil Bath soaps and detergents 0.1%

Citrus Grandis (Grapefruit) Seed Oil Body and hand creams, lotions and powders 0.1%

Citrus Grandis (Grapefruit) Seed Oil Moisturizing creams, lotions and powders 0.1%

Citrus Grandis (Grapefruit) Seed Oil Night creams, lotions and powders 0.1%

Cucurbita Pepo (Pumpkin) Seed Oil Eye lotion 0.003%

Cucurbita Pepo (Pumpkin) Seed Oil Moisturizing creams, lotions and powders 0.1%

Cucurbita Pepo (Pumpkin) Seed Oil Night creams, lotions and powders 0.1%

Euterpe Oleracea Fruit Oil Bath oils, tablets, and salts 0.05%

Euterpe Oleracea Fruit Oil Eye lotion 0.5%

Euterpe Oleracea Fruit Oil Lipstick 0.002%

Euterpe Oleracea Fruit Oil Skin cleansing (cold creams, cleansing lotions, liquids and 0.00001%pads)

Euterpe Oleracea Fruit Oil Other suntan preparations 0.001%

Irvingia Gabonensis Kernel Butter Lipstick 0.003-0.3%

Irvingia Gabonensis Kernel Butter Face and neck creams, lotions, and powders 0.2-0.4%

Irvingia Gabonensis Kernel Butter Body and hand creams, lotions, and powders 0.03%

Limnanthes Alba (Meadowfoam) Seed Oil Bath oils, tablets, and salts 0.9%

Limnanthes Alba (Meadowfoam) Seed Oil Bubble baths 0.5%

Limnanthes Alba (Meadowfoam) Seed Oil Eyeliner 6-20%

Limnanthes Alba (Meadowfoam) Seed Oil Eye lotion 0.1-0.4%

Limnanthes Alba (Meadowfoam) Seed Oil Other fragrance preparations 3%

Limnanthes Alba (Meadowfoam) Seed Oil Hair conditioners 0.1-1%

Limnanthes Alba (Meadowfoam) Seed Oil Tonics, dressings, and other hair grooming aids 0.5%

Lirnnanthes Alba (Meadowfoam) Seed Oil Hair dyes and colors (all types requiring caution statement 0.2-2%and patch test)

Lininanthes Alba (Meadowfoam) Seed Oil Foundations 0.01-5%

Limnanthes Alba (Meadowfoam) Seed Oil Lipstick 0.6-26%

Lirnnanthes Alba (Meadowfoam) Seed Oil Cuticle softeners 0.5%

Limnanthes Alba (Meadowfoam) Seed Oil Bath soaps and detergents 0.01%

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Linmarithes Alba (Meadowfoam) Seed Oil Other personal cleanliness products 0.6%

Linmanthes Alba (Meadowfoam) Seed Oil Shaving cream (aerosol, brushless, and lather) 0.05%

Limnanthes Alba (Meadowfoam) Seed Oil Skin cleansing (cold creams, cleansing lotions, liquids and 0.002%pads)

Limnanthes Alba (Meadowfoam) Seed Oil Depilatories 2%

Linmanthes Alba (Meadowfoam) Seed Oil Face and neck creams, lotions, and powders 0.08-72%

Linmanthes Alba (Meadowfoam) Seed Oil Body and hand creams, lotions, and powders 0.005-27%

Limnanthes Alba (Meadowfoam) Seed Oil Body and hand sprays 0.1%

Limnanthes Alba (Meadowfoam) Seed Oil Moisturizing creams, lotions and powders 0.04- 74%

Limnanthes Alba (Meadowfoam) Seed Oil Night creams, lotions and powders 0.04-3%

Limnanthes Alba(Meadowfoam) Seed Oil Other skin care preparations 0.1-1%

Linum Usitatissimum (Linseed) Seed Oil Bath oils, tablets, and salts 0.02%

Linum Usitatissimum (Linseed) Seed Oil Bubble baths 0.2%

Linum Usitatissimum (Linseed) Seed Oil Eye lotion 0.01%

Linum Usitatissimum (Linseed) Seed Oil Mascara 10%

Linum Usitatissimum (Linseed) Seed Oil Hair conditioners 0.00 1-0.01%

Linum Usitatissimum (Linseed) Seed Oil Shampoos (noncoloring) 0.00 1-0.1%

Linum Usitatissimum (Linseed) Seed Oil Tonics, dressings, and other hair 0.01%

Linum Usitatissimum (Linseed) Seed Oil Lipstick 0.0 1%

Linum Usitatissimum (Linseed) Seed Oil Cuticle softeners 0.05%

Linum Usitatissimum (Linseed) Seed Oil Nail polish and enamel 0.002%

Linum Usitatissimum (Linseed) Seed Oil Bath soaps and detergents 0.003-0.4%

Linum Usitatissimum (Linseed) Seed Oil Deodorants (underarm) 0.05-0.1%

Linum Usitatissimum (Linseed) Seed Oil Aftershave lotions 4%

Linum Usitatissimum (Linseed) Seed Oil Skin cleansing (cold creams, cleansing lotions, liquids and 0.01-1%pads)

Linum Usitatissimum (Linseed) Seed Oil Face and neck creams, lotions, and powders 0.0 1-0.5%

Linum Usitatissimum (Linseed) Seed Oil Body and hand creams, lotions, and powders 0.1-0.2%

Linum Usitatissimum (Linseed) Seed Oil Moisturizing creams, lotions and powders 0.01-0.1%

Linum Usitatissimum (Linseed) Seed Oil Night creams, lotions and powders 0.1%

Mangifera Indica (Mango) Seed Oil Eyeliner 5%

Mangifera Indica (Mango) Seed Oil Hair conditioners 0.2%

Mangifera Indica (Mango) Seed Oil Hair straighteners 0.05%

Page6of 15


Mangifera Indica (Mango) Seed Oil Shampoos (noncoloring) 0.1%

Mangifera Indica (Mango) Seed Oil Tonics, dressings, and other hair grooming aids 0.01%

Mangifera Indica (Mango) Seed Oil Hair dyes and colors (all types requiring caution statement 0.05%and patch test)

Mangifera Indica (Mango) Seed Oil Lipstick 0.03-6%

Mangifera Indica (Mango) Seed Oil Bath soaps and detergents 0.1%

Mangifera Indica (Mango) Seed Oil Skin cleansing (cold creams, cleansing lotions, liquids and 0.003-0.5%pads)

Mangifera Indica (Mango) Seed Oil Face and neck creams, lotions, and powders 0.2-3%

Mangifera Indica (Mango) Seed Oil Body and hand creams, lotions, and powders 0.1-0.9%

Mangifera Indica (Mango) Seed Oil Moisturizing creams, lotions and powders 0.08%

Mangifera Indica (Mango) Seed Oil Night creams, lotions and powders 0.08%

Mangifera Indica (Mango) Seed Oil Other skin care preparations 1%

Mangifera Indica (Mango) Seed Oil Indoor tanning preparations 0.1%

Mangifera Indica (Mango) Seed Butter Eye shadow 0.02%

Mangifera Indica (Mango) Seed Butter Hair sprays (aerosol fixatives) 0.02%

Mangifera Indica (Mango) Seed Butter Shampoos (noncoloring) 0.1-0.5%

Mangifera Indica (Mango) Seed Butter Tonics, dressings, and other hair grooming aids 0.5%

Mangifera Indica (Mango) Seed Butter Blushers (all types) 0.02%

Mangifera Indica (Mango) Seed Butter Face powders 0.02%

Mangifera Indica (Mango) Seed Butter Foundations 0.02-5%

Mangifera Indica (Mango) Seed Butter Lipstick 1-5%

Mangifera Indica (Mango) Seed Butter Makeup bases 0.0 1%

Mangifera Indica (Mango) Seed Butter Cuticle softeners 0.5%

Mangifera Indica (Mango) Seed Butter Bath soaps and detergents 0.0005-0.1%

Mangifera Indica (Mango) Seed Butter Other personal cleanliness products 0.5%

Mangifera Indica (Mango) Seed Butter Shaving cream (aerosol, brushless and lather) 0.1%

Mangifera Indica (Mango) Seed Butter Depilatories 0.05%

Mangifera Indica (Mango) Seed Butter Face and neck creams, lotions, and powders 1-3%

Mangifera Indica (Mango) Seed Butter Body and hand creams, lotions, and powders 0.1-3%

Mangifera Indica (Mango) Seed Butter Moisturizing creams, lotions and powders 0.1%

Mangifera Indica (Mango) Seed Butter Night creams, lotions and powders 0.1%

Mangifera Indica (Mango) Seed Butter Other skin care preparations 0.04-2%

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Moringa Oleifera Seed Oil Skin cleansing (cold creams, cleansing lotions, liquids and 0.0 1%pads)

Moringa Pterygosperma Seed Oil Eye lotion 3%

Moringa Pterygosperma Seed Oil Tonics, dressings, and other hair grooming aids 0.02%

Moringa Pterygosperma Seed Oil Other personal cleanliness products 0.003%

Moringa Pterygosperma Seed Oil Body and hand creams, lotions, and powders 0.004%

Oenothera Biennis (Evening Primrose) Oil Bubble baths 0.2%

Oenothera Biennis (Evening Primrose) Oil Eye lotion 0.00002-0.5%

Oenothera Biennis (Evening Primrose) Oil Eye makeup remover 0.002%

OenotheraBiennis (Evening Primrose) Oil Shampoos (noncoloring) 0.05-0.1%

Oenothera Biennis (Evening Primrose) Oil Tonics, dressings, and other hair grooming aids 0.1%

Oenothera Biennis (Evening Primrose) Oil Blushers (all types) 0.08%

Oenothera Biennis (Evening Primrose) Oil Foundations 58%

Oenothera Biennis (Evening Primrose) Oil Lipstick 0.1-15%

Oenothera Biennis (Evening Primrose) Oil Cuticle softeners 3%

Oenothera Biennis (Evening Primrose) Oil Nail creams and lotions 0.00 1-0.3%

Oenothera Biennis (Evening Primrose) Oil Nail polish and enamel 0.00 1%

Oenothera Biennis (Evening Primrose) Oil Bath soaps and detergents 0.1-0.2%

Oenothera Biennis (Evening Primrose) Oil Deodorants (underarm) 0.2%

Oenothera Biennis (Evening Primrose) Oil Skin cleansing (cold creams, cleansing lotions, liquids and 0.001-0.5%pads)

Oenothera Biennis (Evening Primrose) Oil Face and neck creams, lotions, and powders 0.08-2%

Oenothera Biennis (Evening Primrose) Oil Body and hand creams, lotions, and powders 0.1-2%

Oenothera Biennis (Evening Primrose) Oil Moisturizing creams, lotions and powders 0.04-0.1%

Oenothera Biennis (Evening Primrose) Oil Night creams, lotions and powders 0.008-3%

Oenothera Biennis (Evening Primrose) Oil Paste masks (mud packs) 0.1%

Oenothera Biennis (Evening Primrose) Oil Other skin care preparations 0.002-0.1%

Oenothera Biennis (Evening Primrose) Oil Indoor tanning preparations 0.003%

Oenothera Biennis (Evening Primrose) Oil Other suntan preparations 0.5%

Orbignya Oleifera Seed Oil Bath capsules 0.1%

Orbignya Oleifera Seed Oil Other bath preparations 0.0 1%

Orbignya Oleifera Seed Oil Eye shadow 0.5-0.6%

Orbignya Oleifera Seed Oil Hair conditioners 0.3-2%

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Orbignya Oleifera Seed Oil Hair sprays (aerosol fixatives) 0.02%

Orbignya Oleifera Seed Oil Tonics, dressings, and other hair grooming aids 0.1-1%

Orbignya Oleifera Seed Oil Foundations 0.5%

Orbignya Oleifera Seed Oil Lipstick 0.001-2%

Orbignya Oleifera Seed Oil Bath soaps and detergents 27%

Orbignya Oleifera Seed Oil Skin cleansing (cold creams, cleansing lotions, liquids and 0.05%pads)

Orbignya Oleifera Seed Oil Body and hand creams, lotions, and powders 0.005-1%

Orbignya Oleifera Seed Oil Foot powders and sprays 2%

Orb ignya Oleifera Seed Oil Moisturizing creams, lotions and powders 0.1%

Orb ignya Oleifera Seed Oil Night creams, lotions and powders 0.1%

Orbignya Oleifera Seed Oil Other skin care preparations 4%

Orbignya Oleifera Seed Oil Suntan gels, creams, and liquids 0.0009%

Sodium Babassuate Bath soaps and detergents 8%

Prunus Armeniaca (Apricot) Kernel Oil Baby lotions, oils, powders and creams 4%

Prunus Armeniaca (Apricot) Kernel Oil Other bath preparations 7%

Prunus Armeniaca (Apricot) Kernel Oil Eye shadow 0.002-2%

Prunus Armeniaca (Apricot) Kernel Oil Eye lotion 0.2-9%

Prunus Armeniaca (Apricot) Kernel Oil Eye makeup remover 18%

Prunus Armeniaca (Apricot) Kernel Oil Mascara 0.002-0.05%

Prunus Armeniaca (Apricot) Kernel Oil Powders (dusting and talcum) (excluding aftershave) 0.1%

Prunus Armeniaca (Apricot) Kernel Oil Other fragrance preparations 0.02-1%

Prunus Armeniaca (Apricot) Kernel Oil Hair conditioners 0.003-89%

Prunus Armeniaca (Apricot) Kernel Oil Hair sprays (aerosol fixatives) 0.0009%

Prunus Armeniaca (Apricot) Kernel Oil Hair straighteners 0.0001%

Prunus Armeniaca (Apricot) Kernel Oil Rinses (noncoloring) 0.05%

Prunus Armeniaca (Apricot) Kernel Oil Shampoos (noncoloring) 0.1-0.5%

Prunus Armeniaca (Apricot) Kernel Oil Tonics, dressings, and other hair grooming aids 0.00 1-0.1%

Prunus Armeniaca (Apricot) Kernel Oil Hair dyes and colors (all types requiring caution statement 0.1%and patch test)

Prunus Armeniaca (Apricot) Kernel Oil Blushers (all types) 0.2%

Prunus Armeniaca (Apricot) Kernel Oil Face powders 0.1-0.6%

Prunus Armeniaca (Apricot) Kernel Oil Foundations 0.1-1%

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Prunus Armeniaca (Apricot) Kernel Oil Leg and body paints 0.001%

Prunus Armeniaca (Apricot) Kernel Oil Lipstick 0.00 1-5%

Prunus Armeniaca (Apricot) Kernel Oil Other makeup preparations 0.2%

Prunus Armeniaca (Apricot) Kernel Oil Basecoats and undercoats (manicuring preparations) 0.05%

Prunus Armeniaca (Apricot) Kernel Oil Cuticle softeners 0.05-5%

Prunus Armeniaca (Apricot) Kernel Oil Nail creams and lotions 2-40%

Prunus Armeniaca (Apricot) Kernel Oil Nail polish and enamel 0.05%

Prunus Armeniaca (Apricot) Kernel Oil Nail polish and enamel removers 0.002-0.01%

Prunus Armeniaca (Apricot) Kernel Oil Bath soaps and detergents 0.1-9%

Prunus Armeniaca (Apricot) Kernel Oil Deodorants (underarm) 0.003-0.1%

Prunus Armeniaca (Apricot) Kernel Oil Other personal cleanliness products 0.0 1-0.5%

Prunus Armeniaca (Apricot) Kernel Oil Aftershave lotions 0.5%

Prunus Armeniaca (Apricot) Kernel Oil Shaving cream (aerosol, brushless, and lather) 0.1%

Prunus Armeniaca (Apricot) Kernel Oil Skin cleansing (cold creams, cleansing lotions, liquids and 0.00 1-3%pads)

Prunus Armeniaca (Apricot) Kernel Oil Depilatories 0.00001-2%

Prunus Armeniaca (Apricot) Kernel Oil Face and neck creams, lotions, and powders 0.05-17%

Prunus Armeniaca (Apricot) Kernel Oil Body and hand creams, lotions, and powders 0.03-12%

Prunus Armeniaca (Apricot) Kernel Oil Moisturizing creams, lotions and powders 0.1-3%

Prunus Armeniaca (Apricot) Kernel Oil Night creams, lotions and powders 0.1-8%

Prunus Armeniaca (Apricot) Kernel Oil Paste masks (mud packs) 2%

Prunus Armeniaca (Apricot) Kernel Oil Skin fresheners 0.01%

Prunus Armeniaca (Apricot) Kernel Oil Other skin care preparations 0.0001-0.5%

Prunus Armeniaca (Apricot) Kernel Oil Suntan gels, creams, and liquids 0.0 1-0.05%

Prunus Armeniaca (Apricot) Kernel Oil Indoor tanning preparations 0.01-1%

Prunus Armeniaca (Apricot) Kernel Oil Other suntan preparations 0.0005%

Prunus Avium (Sweet) Cherry Seed Oil Bath soaps and detergents 0.0 1-0.02%

Pninus Domestica Seed Oil [ Preshave lotions (all types) 0.04%

Prunus Persica (Peach) Kernel Oil Bath oils, tablets, and salts 0.1%

Prunus Persica (Peach) Kernel Oil Other bath preparations 1%

Prunus Persica (Peach) Kernel Oil Other fragrance preparations 2%

Prunus Persica (Peach) Kernel Oil Hair dyes and colors (all types requiring caution statement 0.1%and patch test)

Page lOof 15


Prunus Persica (Peach) Kernel Oil Lipstick 0.04-22%

Prunus Persica (Peach) Kernel Oil Skin cleansing (cold creams, cleansing lotions, liquids and 0.003-6%pads)

Prunus Persica (Peach) Kernel Oil Face and neck creams, lotions, and powders 0.2-0.4%

Prunus Persica (Peach) Kernel Oil Body and hand creams, lotions, and powders 0.8-3%

Prunus Persica (Peach) Kernel Oil Moisturizing creams, lotions and powders 0.08%

Prunus Persica (Peach) Kernel Oil Night creams, lotions and powders 0.08%

Prunus Persica (Peach) Kernel Oil Other suntan preparations 0.05%

Ribes Nigrum (Black Currant) Seed Oil Eye lotion 0.08%

Ribes Nigrum (Black Currant) Seed Oil Lipstick 0.03-0.1%

Ribes Nigrum (Black Currant) Seed Oil Nail creams and lotions 0.2%

Ribes Nigrum (Black Currant) Seed Oil Skin cleansing (cold creams, cleansing lotions, liquids and 0.05%pads)

Ribes Nigrum (Black Currant) Seed Oil Body and hand creams, lotions, and powders 0.01%.

Ribes Nigrum (Black Currant) Seed Oil Moisturizing creams, lotions and powders 0.1-0.3%

Ribes Nigrum (Black Currant) Seed Oil Night creams, lotions and powders 0.1%

Ribes Nigrum (Black Currant) Seed Oil Other skin care preparations 0.000001%

Rubus Idaeus (Raspberry) Seed Oil Face and neck creams, lotions, and powders 5%

Rubus Idaeus (Raspberry) Seed Oil Night creams, lotions and powders 0.1%

Sclerocarya Birrea Seed Oil Hair conditioners 1%

Sclerocarya Birrea Seed Oil Shampoos (noncoloring) 1%

Sclerocarya Birrea Seed Oil Body and hand creams, lotions and powders 1%

Sclerocarya Birrea Seed Oil Other skin care preparations 1%

Silybum Marianum Seed Oil Foundations [ 0.5%

Solanum Lycopersicum (Tomato) Fruit Eye shadow 0.0 1%Oil

Solanum Lycopersicum (Tomato) Fruit Blushers (all types) 0.0 1%Oil

Solanum Lycopersicum (Tomato) Fruit Face powders 0.05%Oil

Solanum Lycopersicum (Tomato) Fruit Lipstick 0.00 1%Oil

Solanum Lycopersicum (Tomato) Fruit Other skin care preparations 1%Oil

Theobroma Cacao (Cocoa) Seed Butter Baby lotions, oils, powders and creams 0.0 1%

Page 11 of 15


Theobroma Cacao (Cocoa) Seed Butter Other baby products 0.0 1%

Theobroma Cacao (Cocoa) Seed Butter Bath oils, tablets and salts 0.1%

Theobroma Cacao (Cocoa) Seed Butter Other bath preparations 1%

Theobroma Cacao (Cocoa) Seed Butter Eyebrow pencil 0.02%

Theobroma Cacao (Cocoa) Seed Butter Eyeliner 0.02-9%

Theobroma Cacao (Cocoa) Seed Butter Eye lotion 0.9-4%

Theobroma Cacao (Cocoa) Seed Butter Mascara 0.0002%

Theobroma Cacao (Cocoa) Seed Butter Hair conditioners 1%

Theobroma Cacao (Cocoa) Seed Butter Hair straighteners 0.01%

Theobroma Cacao (Cocoa) Seed Butter Shampoos (noncoloring) 0.0 1-0.1%

Theobroma Cacao (Cocoa) Seed Butter Tonics, dressings and other hair grooming aids 0.1-2%

Theobroma Cacao (Cocoa) Seed Butter Hair dyes and colors (all types requiring caution statement 0.1%and patch test)

Theobroma Cacao (Cocoa) Seed Butter Blushers (all types) 0.4%

Theobroma Cacao (Cocoa) Seed Butter Foundations 0.2-2%

Theobroma Cacao (Cocoa) Seed Butter Lipstick 0.3-37%

Theobroma Cacao (Cocoa) Seed Butter Makeup bases 0.02%

Theobroma Cacao (Cocoa) Seed Butter Makeup fixatives 0.00004%

Theobroma Cacao (Cocoa) Seed Butter Other makeup preparations 9%

Theobroma Cacao (Cocoa) Seed Butter Cuticle softeners 0.1%

Theobroma Cacao (Cocoa) Seed Butter Nail creams and lotions 1%

Theobroma Cacao (Cocoa) Seed Butter Bath soaps and detergents 0.02-2%

Theobroma Cacao (Cocoa) Seed Butter Deodorants (underarm) 0.00 1-1%

Theobroma Cacao (Cocoa) Seed Butter Other personal cleanliness products 0.1%

Theobroma Cacao (Cocoa) Seed Butter Aftershave lotions 1%

Theobroma Cacao (Cocoa) Seed Butter Shaving (aerosol, brushless and lather) 0.0 1-0.1%

Theobroma Cacao (Cocoa) Seed Butter Skin cleansing (cold creams, cleansing lotions, liquids and 0.0001-1%pads)

Theobroma Cacao (Cocoa) Seed Butter Depilatories 0.05-1%

Theobroma Cacao (Cocoa) Seed Butter Face and neck creams, lotions and powders 0.08-3%

Theobroma Cacao (Cocoa) Seed Butter Body and hand creams, lotions and powders 0.000002-6%

Theobroma Cacao (Cocoa) Seed Butter Foot powders and sprays 0.4%

Theobroma Cacao (Cocoa) Seed Butter Moisturizing creams, lotions and powders 2%

Page l2of 15


Theobroma Cacao (Cocoa) Seed Butter Night creams, lotions asd powders 2%

Theobroma Cacao (Cocoa) Seed Butter Other skin care preparations 0.1-25%

Theobroma Cacao (Cocoa) Seed Butter Suntan gels, creams and liquids 5%

Theobroma Cacao (Cocoa) Seed Butter Indoor tanning preparations 0.1-0.5%

Theobroma Cacao (Cocoa) Seed Butter Other suntan preparations 0.5%

Theobroma Grandiflorum Seed Butter Eyeliner 2%

Theobroma Grandiflorum Seed Butter Eye shadow 0.1%

Theobroma Grandiflorum Seed Butter Eye lotion 2%

Theobroma Grandiflorum Seed Butter Hair conditioners 0.001-1%

Theobroma Grandiflorum Seed Butter Shampoos (noncoloring) 0.001-0.1%

Theobroma Grandiflorum Seed Butter Tonics, dressings and other hair grooming aids 0.01%

Theobroma Grandiflorum Seed Butter Other hair preparations (noncoloring) 1%

Theobroma Grandiflorum Seed Butter Foundations 5%

Theobroma Grandiflorum Seed Butter Lipstick 7%

Theobroma Grandiflorum Seed Butter Bath soaps and detergents 0.1%

Theobroma Grandiflorum Seed Butter Deodorants (underarm) 0.1%

Theobroma Grandiflorum Seed Butter Other personal cleanliness products 0.05%

Theobroma Grandiflorum Seed Butter Aftershave lotions 0. t %

Theobroma Grandiflorum Seed Butter Shaving cream (aerosol, brushless and lather) 0.1%

Theobroma Grandiflorum Seed Butter Skin cleansing (cold creams, cleansing lotions, liquids and 0.003%pads)

Theobroma Grandiflorum Seed Butter Face and neck creams, lotions and powders 2-5%

Theobroma Grandiflorum Seed Butter Body and hand creams, lotions and powders 0.1-5%

Theobroma Grandiflorum Seed Butter Moisturizing creams, lotions and powders 0.1%

Theobroma Grandiflorum Seed Butter Night creams, lotions and powders 0.1-3%

Theobroma Grandiflorum Seed Butter Other skin care preparations 0.00005%

Vaccinium Macrocarpon (Cranberry) Seed Hair conditioners 0.1%Oil

Vaccinium Macrocarpon (Cranberry) Seed Shampoos (noncoloring) 0.0 1%Oil

Vaccinium Macrocarpon (Cranberry) Seed Tonics, dressings and other hair grooming aids 0.1%Oil

Vaccinium Macrocarpon (Cranberry) Seed Foundations 0.1%Oil

Page 13 of 15


Vaccinium Macrocarpon (Cranberry) Seed Lipstick 0.3%Oil

Vaccinium Macrocarpon (Cranberry) Seed Other makeup preparations 0.002%Oil

Vaccinium Macrocarpon (Cranberry) Seed Bath soaps and detergents 0.003-0.1%Oil

Vaccinium Macrocarpon (Cranberry) Seed Face and neck creams, lotions and powders 2%Oil

Vaccinium Macrocarpon (Cranberry) Seed Body and hand creams, lotions and powders 0.1%Oil

Vaccinium Macrocarpon (Cranberry) Seed Moisturizing creams, lotions and powders 0.1%Oil

Vaccinium Macrocarpon (Cranberry) Seed Night creams, lotions and powders 0.1%Oil

Vitis Vinifera (Grape) Seed Oil Bath oils, tablets and salts 0.1-0.5%

Vitis Vinifera (Grape) Seed Oil Bubble baths 2%

Vitis Vinifera (Grape) Seed Oil Other bath preparations 0.01%

Vitis Vinifera (Grape) Seed Oil Eye lotion 5%

Vitis Vinifera (Grape) Seed Oil Eye makeup remover 0.01%

Vitis Vinifera (Grape) Seed Oil Perfumes 1%

Vitis Vinifera (Grape) Seed Oil Other fragrance preparations 0.00 1-7%

Vitis Vinifera (Grape) Seed Oil Hair conditioners 0.01-0.3%

Vitis Vinifera (Grape) Seed Oil Shampoos (noncoloring) 0.05-0.1%

Vitis Vinifera (Grape) Seed Oil Tonics, dressings and other hair grooming aids 0.01-0.1%

Vitis Vinifera (Grape) Seed Oil Hair dyes and colors (all types requiring caution statement 43%and patch test)

Vitis Vinifera (Grape) Seed Oil Foundations 0.2%

Vitis Vinifera (Grape) Seed Oil Lipstick 0.03-7%

Vitis Vinifera (Grape) Seed Oil Cuticle softeners 35%

Vitis Vinifera (Grape) Seed Oil Nail creams and lotions 1%

Vitis Vinifera (Grape) Seed Oil Nail polish and enamel 0.00 1%

Vitis Vinifera (Grape) Seed Oil Bath soaps and detergents 0.0 1-7%

Vitis Vinifera (Grape) Seed Oil Deodorants (underarm) 0.00 1-0.2%

Vitis Vinifera (Grape) Seed Oil Other personal cleanliness products 0.001-1%

Vitis Vinifera (Grape) Seed Oil Aftershave lotions 0.1-1%

Page l4of 15


Vitis Vinifera (Grape) Seed Oil Preshave lotions (all types) 16-39%

Vitis Vinifera (Grape) Seed Oil Shaving cream (aerosol, brushless and lather) 2%

Vitis Vinifera (Grape) Seed Oil Other shaving preparations 0.1%

Vitis Vinifera (Grape) Seed Oil Skin cleansing (cold creams, cleansing lotions, liquids and 0.004-20%pads)

Vitis Vinifera (Grape) Seed Oil Depilatories 0.5%

Vitis Vinifera (Grape) Seed Oil Face and neck creams, lotions and powders 0.1-8%

Vitis Vinifera (Grape) Seed Oil Body and hand creams, lotions and powders 0.0141%

Vitis Vinifera (Grape) Seed Oil Body and hand sprays 1%

Vitis Vinifera (Grape) Seed Oil Moisturizing creams, lotions and powders 0.0 1-5%

Vitis Vinifera (Grape) Seed Oil Night creams, lotions and powders 0.0 1-5%

Vitis Vinifera (Grape) Seed Oil Paste masks (mud packs) 0.01%

Vitis Vinifera (Grape) Seed Oil Other skin care preparations 0.01-13%

Vitis Vinifera (Grape) Seed Oil Indoor tanning preparations 0.00 1%

Vitis Vinifera (Grape) Seed Oil Other suntan preparations 15%

Hydrogenated Grapeseed Oil Other bath preparations 0.5%

Hydrogenated Grapeseed Oil Lipstick 0.5%

Hydrogenated Grapeseed Oil Cuticle softeners 0.3%

Ingredients included in the title of the table, out not found in the table were included in the survey, but no uses were reportedInformation collected in 2010Table prepared May 13, 2010

The following ingredients will be included in a later concentration of use survey: Camellia Japonica Seed Oil, Citrus Aurantifolia(Lime) Seed Oil Unsaponifiables, Persea Gratissima (Avocado) Oil, Hydrogenated Avocado Oil, Persea Gratissima (Avocado)Butter, Persea Gratissima (Avocado) Oil Unsaponifiables, Sodium Avocadoate, Triticum Vulgare (Wheat) Germ Oil,Hydrogenated Wheat Germ Oil, Hydrogenated Wheat Germ Oil Unsaponifiables, Triticum Aestivum (Wheat) Germ Oil, TriticumVulgare (Wheat) Germ Oil Unsaponifiables and Wheat Germ Acid.

Page 15 of 15


Personal Care Products CouncilCommitted to Safety,

ua if y nnovaf ion

Memorandum

TO: F. Alan Andersen, Ph.D.Director - COSMETIC INGREDIENT REVIEW (CIR)

FROM: John Bailey, Ph.D.Industry Liaison to the CIR Expert Panel

DATE: July 12, 2010

SUBJECT: Concentration of Use Plant Oils May 2010 Use Survey


Concentration of Use by FDA Product CategoryGossypium Herbaceum (Cotton) Seed Oil, Cottonseed Acid, Hydrogenated Cottonseed Oil, Elaeis Guinennsis

(Palm) Oil, Elaeis Guinennsis (Palm) Kernel Oil, Hydrogenated Palm Oil, Hydrogenated Palm Kernel Oil,Elaeis Guineensis (Palm) Butter, Elaeis Oleifera Kernel Oil, Elaeis (Palm) Oil, Hydrogenated Palm Acid,Palm Acid, Palm Kernel Acid, Potassium Palmate, Potassium Hydrogenated Palmate, Potassium PalmKernelate, Sodium Hydrogenated Palmate, Sodium Palmate, Sodium Palm Kernelate, HydrogenatedSafflower Seed Oil, Potassium Safflowerate, Safflower Acid, Sodium Safflowerate, Sesamum Indicum

(Sesame) Seed Butter, Persea Gratissima (Avocado) Oil, Hydrogenated Avocado Oil, Persea Gratissima(Avocado) Butter, Persea Gratissima (Avocado) Oil Unsaponifiables, Sodium Avocadoate, Oryza Sativa

(Rice) Bran Oil, Oryza Sativa (Rice) Germ Oil, Rice Bran Acid, Hydrogenated Rice Bran Oil, Oryza Sativa(Rice) Seed Oil, Triticum Vulgare (Wheat) Germ Oil, Triticum Vulgare (Wheat) Germ Oil Unsaponifiables,

Hydrogenated Wheat Germ Oil, Hydrogenated Wheat Germ Oil Unsaponifiables, Triticum Aestivum(Wheat) Germ Oil, Wheat Germ Acid, Camellia Japonica Seed Oil, Citrus Aurantifolia (Lime) Seed Oil

Unsaponifiables

Ingredient Product Category Concentration ofUse

Gossypium Herbaceum (Cottonseed) Oil Eyeliner 0.1-11%

Gossypium Herbaceum (Cottonseed) Oil Eye shadow 0.1%

Gossypium Herbaceum (Cottonseed) Oil Eye lotion 0.5%

Gossypium Herbaceum (Cottonseed) Oil Foundations 0.5%

Gossypium Herbaceum (Cottonseed) Oil Lipstick 0.2-1%

Gossypium Herbaceum (Cottonseed) Oil Nail creams and lotions 30-32%

Gossypium Herbaceum (Cottonseed) Oil Other manicuring preparations 0.5%

Gossypium Herbaceum (Cottonseed) Oil Bath soaps and detergents 0.1%

Gossypium Herbaceum (Cottonseed) Oil Deodorants (underarm) 0.2%

Gossypium Herbaceum (Cottonseed) Oil Other personal cleanliness products 0.004-0.01%

Gossypium Herbaceum (Cottonseed) Oil Preshave lotions (all types) 29%

Gossypium Herbaceum (Cottonseed) Oil Shaving creams (aerosol, brushless and 1%lather)

Gossypium Herbaceum (Cottonseed) Oil Skin cleansing (cold creams, cleansing 0.5%lotions, liquids and pads)

Gossypium Herbaceum (Cottonseed) Oil Face and neck creams, lotions and powders 0.5%

Gossypium Herbaceum (Cottonseed) Oil Body and hand creams, lotions and powders 0.3-2%

Gossypium Herbaceum (Cottonseed) Oil Body and hand sprays 0.2%

Gossypium Herbaceum (Cottonseed) Oil Moisturizing creams, lotions and powders 0.08%

Gossypium Herbaceum (Cottonseed) Oil Night creams, lotions and powders 0.08-2%

Page 1 of 9


Gossypium Herbaceum (Cottonseed) Oil Other skin care preparations 5%

Hydrogenated Cottonseed Oil Eyebrow pencil 1 1-24%

Hydrogenated Cottonseed Oil Eyeliner 8-15%

Hydrogenated Cottonseed Oil Mascara 0.5%

Hydrogenated Cottonseed Oil Other eye makeup preparations 8%

Hydrogenated Cottonseed Oil Hair conditioners 0.0 1%

Hydrogenated Cottonseed Oil Shampoos (noncoloring) 0.01%

Hydrogenated Cottonseed Oil Tonics, dressings and other hair grooming 0.1%aids

Hydrogenated Cottonseed Oil Foundations 5%

Hydrogenated Cottonseed Oil Lipstick 8-12%

Hydrogenated Cottonseed Oil Other makeup preparations 0.002-1 1%

Hydrogenated Cottonseed Oil Face and neck creams, lotions and powders 0.005-5%

Hydrogenated Cottonseed Oil Other skin care preparations 0.00 1%

Elaeis Guineensis (Palm) Oil Eye lotion 0.04-2%

Elaeis Guineensis (Palm) Oil Hair conditioners 2%

Elaeis Guineensis (Palm) Oil Tonics, dressings and other hair grooming 13%aids

Elaeis Guineensis (Palm) Oil Other hair preparations (noncoloring) 34%

Elaeis Guineensis (Palm) Oil Foundations 5%

Elaeis Guineensis (Palm) Oil Lipstick 2%

Elaeis Guineensis (Palm) Oil Bath soaps and detergents 48%

Elaeis Guineensis (Palm) Oil Other personal cleanliness products 0.002%

Elaeis Guineensis (Palm) Oil Aftershave lotions 0.5%

Elaeis Guineensis (Palm) Oil Skin cleansing (cold creams, cleansing 0.002-8%lotions, liquids and pads)

Elaeis Guineensis (Palm) Oil Face and neck creams, lotions and powders 0.008-4%

Elaeis Guineensis (Palm) Oil Body and hand creams, lotions and powders 4-6%

Elaeis Guineensis (Palm) Oil Moisturizing creams, lotions and powders 0.4-3%

Elaeis Guineensis (Palm) Oil Night creams, lotions and powders 3-4%

Elaeis Guineensis (Palm) Oil Paste masks (mud packs) 4-5%

Page 2 of 9


Elaeis Guineensis (Palm) Oil Other skin care preparations 0.9-2%

Elaeis Guineensis (Palm) Kernel Oil Eye lotion 0.8%

Elaeis Guineensis (Palm) Kernel Oil Shampoos (noncoloring) 0.9-23%

Elaeis Guineensis (Palm) Kernel Oil Other manicuring preparations 3%

Elaeis Guineensis (Palm) Kernel Oil Bath soaps and detergents 0.05%

Elaeis Guineensis (Palm) Kernel Oil Shaving cream (aerosol, brushless and 0.05%lather)

Elaeis Guineensis (Palm) Kernel Oil Moisturizing creams, lotions and powders 0.8%

Elaeis Guineensis (Palm) Kernel Oil Other skin care preparations 2%

Hydrogenated Palm Oil Eyebrow pencil 3-5%

Hydrogenated Palm Oil Eyeliner 2-30%

Hydrogenated Palm Oil Eye lotion 0.9%

Hydrogenated Palm Oil Mascara 0.2%

Hydrogenated Palm Oil Colognes and toilet waters 1%

Hydrogenated Palm Oil Face powders 0.4%

Hydrogenated Palm Oil Foundations 8%

Hydrogenated Palm Oil Lipstick 2-30%

Hydrogenated Palm Oil Makeup bases 1%

Hydrogenated Palm Oil Makeup fixatives 0.5%

Hydrogenated Palm Oil Other makeup preparations 25%

Hydrogenated Palm Oil Bath soaps and detergents 2%

Hydrogenated Palm Oil Face and neck creams, lotions and powders 2%

Hydrogenated Palm Oil Body and hand creams, lotions and powders 10%

Hydrogenated Palm Oil Moisturizing creams, lotions and powders 3%

Hydrogenated Palm Oil Paste masks (mud packs) 2%

Hydrogenated Palm Oil Other skin care preparations 3%

Hydrogenated Palm Oil Suntan gels, creams and liquids 1%

Hydrogenated Palm Kernel Oil Eyebrow pencil 2%

Hydrogenated Palm Kernel Oil Eyeliner 7-10%

Hydrogenated Palm Kernel Oil Foundations 0.4%

Page 3 of 9


Hydrogenated Palm Kernel Oil Lipstick 3-13%

Hydrogenated Palm Kernel Oil Bath soaps and detergents 0.9-2%

Hydrogenated Palm Kernel Oil Face and neck creams, lotions and powders 1-5%

Hydrogenated Palm Kernel Oil Body and hand creams, lotions and powders 0.6-3%

Hydrogenated Palm Kernel Oil Moisturizing creams, lotions and powders 2%

Hydrogenated Palm Kernel Oil Night creams, lotions and powders 3%

Hydrogenated Palm Kernel Oil Paste masks (mud packs) 0.6-1%

Hydrogenated Palm Kernel Oil Suntan gels, creams and liquids 0.6%

Palm Acid Bath soaps and detergents 1-4%

Palm Acid Skin cleansing (cold creams, cleansing 17%lotions, liquids and pads)

Palm Kernel Acid Bath soaps and detergents 0.2-3%

Palm Kernel Acid Skin cleansing (cold creams, cleansing 12%lotions, liquids

Potassium Palmate I Bath soaps and detergents 0.3-3%

Potassium Palm Kernelate I Bath soaps and detergents 0.3-30%

Sodium Palmate Bath soaps and detergents 3-68%

Sodium Palmate Shaving soap (cakes, sticks, etc.) 63%

Sodium Palmate Skin cleansing (cold creams, cleansing 28%lotions, liquids and pads)

Sodium Palm Kernelate Bath soaps and detergents 16-44%

Sodium Palm Kernelate Shaving soaps (cakes, sticks, etc.) 15%

Sodium Palm Kernelate Skin cleansing (cold creams, cleansing 12%lotions, liquids and pads)

-

Persea Gratissima (Avocado) Oil Bath oils, tablets and salts 0.6-6%

Persea Gratissima (Avocado) Oil Eyeliner 0.1-1%

Persea Gratissima (Avocado) Oil Eye shadow 0.1%

Persea Gratissima (Avocado) Oil Eye lotion 0.05-2%

Persea Gratissima (Avocado) Oil Eye makeup remover 2%

Persea Gratissima (Avocado) Oil Mascara 0.2%

Persea Gratissima (Avocado) Oil Perfumes 8%

Page 4 of 9


Persea Gratissima (Avocado) Oil Powders (dusting and talcum) 02%

Persea Gratissima (Avocado) Oil Other fragrance preparations 1%

Persea Gratissima (Avocado) Oil Hair conditioners 0.0001-15%

Persea Gratissima (Avocado) Oil Hair sprays (aerosol fixatives) 0.05%

Persea Gratissima (Avocado) Oil Shampoos (noncoloring) 0.01-1%

Persea Gratissima (Avocado) Oil Tonics, dressings and other hair grooming 41%aids

Persea Gratissima (Avocado) Oil Hair dyes and colors (all types requiring 0.3%caution Statement and patch test)

Persea Gratissima (Avocado) Oil Hair rinses (coloring) 0.3%

Persea Gratissima (Avocado) Oil Blushers (all types) 0.2-0.5%

Persea Gratissima (Avocado) Oil Face powders 0.1-0.3%

Persea Gratissima (Avocado) Oil Foundations 0.0 1-3%

Persea Gratissima (Avocado) Oil Lipstick 0.05-26%

Persea Gratissima (Avocado) Oil Makeup bases 2%

Persea Gratissima (Avocado) Oil Other makeup preparations 0.1%

Persea Gratissima (Avocado) Oil Cuticle softeners 18-19%

Persea Gratissima (Avocado) Oil Nail creams and lotions 2-5%

Persea Gratissima (Avocado) Oil Nail polish and enamel 0.00 1%

Persea Gratissima (Avocado) Oil Other manicuring preparations 34%

Persea Gratissima (Avocado) Oil Bath soaps and detergents 0.02-0.5%

Persea Gratissima (Avocado) Oil Deodorants (underarm) 0.1%

Persea Gratissima (Avocado) Oil Other personal cleanliness products 1-3%

Persea Gratissima (Avocado) Oil Aftershave lotions 0.5%

Persea Gratissima (Avocado) Oil Preshave lotions (all types) 0.00 1%

Persea Gratissima (Avocado) Oil Shaving cream (aerosol. brushless and 0.05%lather)

Persea Gratissima (Avocado) Oil Other shaving preparations 0.8-2%

Persea Gratissima (Avocado) Oil Skin cleansing (cold creams, cleansing 0.003-3%lotions, liquids and pads)

Persea Gratissima (Avocado) Oil Depilatories 0. 1%

Page 5 of 9


Persea Gratissima (Avocado) Oil Face and neck creams, lotions and powders 0.01-98%

Persea Gratissima (Avocado) Oil Body and hand creams, lotions and powders 0.01-6%

Persea Gratissima (Avocado) Oil Foot powders and sprays 0.0 1%

Persea Gratissima (Avocado) Oil Moisturizing creams, lotions and powders 0.1-2%

Persea Gratissima (Avocado) Oil Night creams, lotions and powders 0.02-1%

Persea Gratissima (Avocado) Oil Paste masks (mud packs) 0.3-2%

Persea Gratissima (Avocado) Oil Other skin care preparations 0.1-31%

Persea Gratissima (Avocado) Oil Suntan gels, creams and liquids 0.02-2%

Persea Gratissima (Avocado) Oil Indoor tanning preparations 0.0005-0.5%

Hydrogenated Avocado Oil Other hair preparations (noncoloring) 0.5%

Persea Gratissima (Avocado) Oil Eye shadow 0.5%Unsaponifiables

Persea Gratissima (Avocado) Oil Tonics, dressings and other hair grooming 6%Unsaponifiables aids

Persea Gratissima (Avocado) Oil Lipstick 3%Unsaponifiables

Persea Gratissima (Avocado) Oil Skin cleansing (cold creams, cleansing 0.2%Unsaponifiables lotions , liquids and pads)

Oryza Sativa (Rice) Bran Oil Bath oils, tablets and salts 0.2%

Oryza Sativa (Rice) Bran Oil Eyeliner 0.8%

Oryza Sativa (Rice) Bran Oil Eye shadow 0.5%

Oryza Sativa (Rice) Bran Oil Eye lotion 0.5-0.6%

Oryza Sativa (Rice) Bran Oil Hair conditioners 0.2-0.3%

Oryza Sativa (Rice) Bran Oil Hair sprays (aerosol fixatives) 0.1%

Oryza Sativa (Rice) Bran Oil Shampoos (noncoloring) 0.005-0.3%

Oryza Sativa (Rice) Bran Oil Tonics, dressings and other hair grooming 0.02-0.5%aids

Oryza Sativa (Rice) Bran Oil Other hair preparations (noncoloring) 0.3%

Oryza Sativa (Rice) Bran Oil Hair rinses (coloring) 0.3%

Oryza Sativa (Rice) Bran Oil Face powders 0.3%

Oryza Sativa (Rice) Bran Oil Foundations 0.1-1%

Oryza Sativa (Rice) Bran Oil Lipstick 0.1-8%

Page 6 of 9


Oryza Sativa (Rice) Bran Oil Makeup bases 0.4%

Oryza Sativa (Rice) Bran Oil Nail creams and lotions 3-78%

Oryza Sativa (Rice) Bran Oil Nail polish and enamel 0.02%

Oryza Sativa (Rice) Bran Oil Other manicuring preparations 0.1%

Oryza Sativa (Rice) Bran Oil Bath soap and detergents 1%

Oryza Sativa (Rice) Bran Oil Deodorants (underarm) 0.5%

Oryza Sativa (Rice) Bran Oil Other personal cleanliness products 0.0006-6%

Oryza Sativa (Rice) Bran Oil Aftershave lotions 0.5%

Oryza Sativa (Rice) Bran Oil Preshave lotions (all types) 1%

Oryza Sativa (Rice) Bran Oil Skin cleansing (cold creams, cleansing 0.2-0.6%lotions, liquids and pads)

Oryza Sativa (Rice) Bran Oil Depilatories 0.5%

Oryza Sativa (Rice) Bran Oil Face and neck creams, lotions and powders 0.1-27%

Oryza Sativa (Rice) Bran Oil Body and hand creams, lotions and powders 0.5-5%

Oryza Sativa (Rice) Bran Oil Body and hand sprays 0.0003%

Oryza Sativa (Rice) Bran Oil Moisturizing creams, lotions and powders 8%

Oryza Sativa (Rice) Bran Oil Night creams, lotions and powders 4-5%

Oryza Sativa (Rice) Bran Oil Other skin care preparations 0.5-27%

Oryza Sativa (Rice) Germ Oil Bath oils, tablets and salts 3%

Oryza Sativa (Rice) Germ Oil Bubble baths 0.03%

Oryza Sativa (Rice) Germ Oil Eyebrow pencil 0.1%

Oryza Sativa (Rice) Germ Oil Eyeliner 0.1%

Oryza Sativa (Rice) Germ Oil Eye shadow 0.01%

Oryza Sativa (Rice) Germ Oil Eye makeup remover 0.01-0.1%

Oryza Sativa (Rice) Germ Oil Mascara 0.1-1%

Oryza Sativa (Rice) Germ Oil Blushers (all types) 0.1%

Oryza Sativa (Rice) Germ Oil Face powders 0.01%

Oryza Sativa (Rice) Germ Oil Foundations 0.1%

Oryza Sativa (Rice) Germ Oil Lipstick 0.1-3%

Oryza Sativa (Rice) Germ Oil Makeup bases 0.1%

Page 7 of 9


Oryza Sativa (Rice) Germ Oil Bath soaps and detergents 0.5%

Oryza Sativa (Rice) Germ Oil Deodorants (underarm) 0.003%

Oryza Sativa (Rice) Germ Oil Other personal cleanliness products 0.003-0.005%

Oryza Sativa (Rice) Germ Oil Skin cleansing (cold creams, cleansing 0.003-0.01%lotions, liquids and pads)

Oryza Sativa (Rice) Germ Oil Face and neck creams, lotions and powders 0.2-3%

Oryza Sativa (Rice) Germ Oil Body and hand creams, lotions and powders 0.02-2%

Oryza Sativa (Rice) Germ Oil Moisturizing creams, lotions and powders 0.01-0.1%

Oryza Sativa (Rice) Germ Oil Night creams, lotions and powders 0.08%

Oryza Sativa (Rice) Germ Oil Paste masks (mud packs) 0.0 1%

Oryza Sativa (Rice) Germ Oil Other skin care preparations 0.1%

Oryza Sativa (Rice) Germ Oil Suntan gels, creams and liquids 0.01%

Triticum Vulgare (Wheat) Germ Oil Bath oils, tablets and salts 0.5%

Triticum Vulgare (Wheat) Germ Oil Eye shadow 0.02%

Triticum Vulgare (Wheat) Germ Oil Eye lotion 0.1-0.5%

Triticum Vulgare (Wheat) Germ Oil Eye makeup remover 0.01%

Triticum Vulgare (Wheat) Germ Oil Mascara 0.05-0.1%

Triticum Vulgare (Wheat) Germ Oil Hair conditioners 0.00 1-0.5%

Triticum Vulgare (Wheat) Germ Oil Hair sprays (aerosol fixatives) 0.0001-00005%

Triticum Vulgare (Wheat) Germ Oil Shampoos (noncoloring) 0.00 1-0.5%

Triticum Vulgare (Wheat) Germ Oil Tonics, dressings and other hair grooming 0.00 1-0.5%aids

Triticum Vulgare (Wheat) Germ Oil Other hair preparations (noncoloring) 0.1%

Triticum Vulgare (Wheat) Germ Oil Hair dyes and colors (all types requiring 0.0 1-0.2%caution statement and patch test)

Triticum Vulgare (Wheat) Germ Oil Face powders 0.1%

Triticum Vulgare (Wheat) Germ Oil Foundations 0.00 1-2%

Triticum Vulgare (Wheat) Germ Oil Lipstick 0.3-5%

Triticum Vulgare (Wheat) Germ Oil Makeup bases 0.1%

Triticum Vulgare (Wheat) Germ Oil Cuticle softeners 1%

Triticum Vulgare (Wheat) Germ Oil Nail creams and lotions 3%

Page 8 of 9


Triticum Vulgare (Wheat) Germ Oil Other manicuring preparations 0.1-28%

Triticum Vulgare (Wheat) Germ Oil Bath soaps and detergents 0.0 1-0.5%

Triticum Vulgare (Wheat) Germ Oil Other personal cleanliness products 0.2%

Triticum Vulgare (Wheat) Germ Oil Skin cleansing (cold creams, cleansing 0.0 1-2%lotions , liquids and pads)

Triticum Vulgare (Wheat) Germ Oil Depilatories 0.6%

Triticum Vulgare (Wheat) Germ Oil Face and neck creams, lotions and powders 0.001-20%

Triticum Vulgare (Wheat) Germ Oil Body and hand creams, lotions and powders 0.3-1%

Triticum Vulgare (Wheat) Germ Oil Moisturizing creams, lotions and powders 0.5%

Triticum Vulgare (Wheat) Germ Oil Night creams, lotions and powders 0.08-0.5%

Triticum Vulgare (Wheat) Germ Oil Paste masks (mud packs) 2%

Triticum Vulgare (Wheat) Germ Oil Other skin care preparations 0.1-23%

Triticum Vulgare (Wheat) Germ Oil Suntan gels, creams and liquids 0.04%

Triticum Vulgare (Wheat) Germ Oil Indoor tanning preparations 0.0005%

Triticum Vulgare (Wheat) Germ Oil Face and neck creams, lotions and powders 0.2%Unsaponifiables

Triticum Aestivüm (Wheat) Germ Oil Hair conditioners <1%

Triticum Aestivum (Wheat) Germ Oil Hair straighteners <1%

Triticum Aestivum (Wheat) Germ Oil Moisturizing creams, lotions and powders <1%

Camellia Japonica Seed Oil Eye shadow 0.01%

Camellia Japonica Seed Oil Rinses (noncoloring) 0.1%

Camellia Japonica Seed Oil Blushers (all types) 0.01%

Camellia Japonica Seed Oil Lipstick 0.1%

Camellia Japonica Seed Oil Deodorants (underarm) 0.0 1%

Camellia Japonica Seed Oil Other personal cleanliness products 0.1%

Camellia Japonica Seed Oil Moisturizing creams, lotions and powders 0.2%*Ingredients included in the title of the table but not found in the table were included in the concentration of usesurvey, but no uses were reported.

Information collected in 2010Table prepared July 12, 2010

Page 9 of 9


Persona’ Care Products CouncilCommitted to Safety,Quality & Innovation

Memorandum


FROM: CIR Science and Support Committee

DATE: July2l,2010

SUBJECT: Concentration of Use Plant Oils Updated May 2010 Survey

1101 17th Street, N.W., Suite 300 Washington, D.C. 20036-4702 202.331.1770 I 202.331.1969 (fax) www.personalcarecouncil.org CIR Panel Book Page 130

Concentration of Use by FDA Product CategoryGossypium Herbaceum (Cotton) Seed Oil, Cottonseed Acid, Hydrogenated Cottonseed Oil, Elaeis Guinennsis

(Palm) Oil, Elaeis Guinennsis (Palm) Kernel Oil, Hydrogenated Palm Oil, Hydrogenated Palm Kernel Oil,Elaeis Guineensis (Palm) Butter, Elaeis Oleifera Kernel Oil, Elaeis (Palm) Oil, Hydrogenated Palm Acid,

Palm Acid, Palm Kernel Acid, Potassium Palmate, Potassium Hydrogenated Palmate, Potassium PalmKernelate, Sodium Hydrogenated Palmate, Sodium Palmate, Sodium Palm Kernelate, HydrogenatedSafflower Seed Oil, Potassium Safflowerate, Safflower Acid, Sodium Safflowerate, Sesamum Indicum

(Sesame) Seed Butter, Persea Gratissima (Avocado) Oil, Hydrogenated Avocado Oil, Persea Gratissima(Avocado) Butter, Persea Gratissima (Avocado) Oil Unsaponifiables, Sodium Avocadoate, Oryza Sativa

(Rice) Bran Oil, Oryza Sativa (Rice) Germ Oil, Rice Bran Acid, Hydrogenated Rice Bran Oil, Oryza Sativa(Rice) Seed Oil, Triticum Vulgare (Wheat) Germ Oil, Triticum Vulgare (Wheat) Germ Oil Unsaponiflables,

Hydrogenated Wheat Germ Oil, Hydrogenated Wheat Germ Oil Unsaponiflables, Triticum Aestivum(Wheat) Germ Oil, Wheat Germ Acid, Camellia Japonica Seed Oil, Citrus Aurantifolia (Lime) Seed Oil

Unsaponifiables

Ingredient Product Category Concentration ofUse

Gossypium Herbaceum (Cottonseed) Oil Eyeliner 0.1-11%

Gossypium Herbaceum (Cottonseed) Oil Eye shadow 0.1%

Gossypium Herbaceum (Cottonseed) Oil Eye lotion 0.5%

Gossypium Herbaceum (Cottonseed) Oil Foundations 0.5%

Gossypium Herbaceum (Cottonseed) Oil Lipstick 0.2-1%

Gossypium Herbaceum (Cottonseed) Oil Nail creams and lotions 30-32%

Gossypium Herbaceum (Cottonseed) Oil Other manicuring preparations 0.5%

Gossypium Herbaceum (Cottonseed) Oil Bath soaps and detergents 0.1%

Gossypium Herbaceum (Cottonseed) Oil Deodorants (underarm) 0.2%

Gossypium Herbaceum (Cottonseed) Oil Other personal cleanliness products 0.004-0.01%

Gossypium Herbaceum (Cottonseed) Oil Preshave lotions (all types) 29%

Gossypium Herbaceum (Cottonseed) Oil Shaving creams (aerosol, brushless and 1%lather)

Gossypium Herbaceum (Cottonseed) Oil Skin cleansing (cold creams, cleansing 0.5%lotions, liquids and pads)

Gossypium Herbaceum (Cottonseed) Oil Face and neck creams, lotions and powders 0.5%

Gossypium Herbaceum (Cottonseed) Oil Body and hand creams, lotions and powders 0.3-2%

Gossypium Herbaceum (Cottonseed) Oil Body and hand sprays 0.2%

Gossypium Herbaceum (Cottonseed) Oil Moisturizing creams, lotions and powders 0.08%

Gossypium Herbaceum (Cottonseed) Oil Night creams, lotions and powders 0.08-2%

Page 1 of 9


Gossypium Herbaceum (Cottonseed) Oil Other skin care preparations 5%

Hydrogenated Cottonseed Oil Eyebrow pencil 11-24%

Hydrogenated Cottonseed Oil Eyeliner 8-15%

Hydrogenated Cottonseed Oil Mascara 0.5%

Hydrogenated Cottonseed Oil Other eye makeup preparations 8%

Hydrogenated Cottonseed Oil Hair conditioners 0.01%

Hydrogenated Cottonseed Oil Shampoos (noncoloring) 0.01%

Hydrogenated Cottonseed Oil Tonics, dressings and other hair grooming 0.1%aids

Hydrogenated Cottonseed Oil Foundations 5%

Hydrogenated Cottonseed Oil Lipstick 8-12%

Hydrogenated Cottonseed Oil Other makeup preparations 0.002-11%

Hydrogenated Cottonseed Oil Face and neck creams, lotions and powders 0.005-5%

Hydrogenated Cottonseed Oil Other skin care preparations 0.00 1%

Elaeis Guineensis (Palm) Oil Eye lotion 0.04-2%

Elaeis Guineensis (Palm) Oil Hair conditioners 2%

Elaeis Guineensis (Palm) Oil Tonics, dressings and other hair grooming 13%aids

Elaeis Guineensis (Palm) Oil Other hair preparations (noncoloring) 34%

Elaeis Guineensis (Palm) Oil Foundations 5%

Elaeis Guineensis (Palm) Oil Lipstick 2%

Elaeis Guineensis (Palm) Oil Bath soaps and detergents 48%

Elaeis Guineensis (Palm) Oil Other personal cleanliness products 0.002%

Elaeis Guineensis (Palm) Oil Aftershave lotions 0.5%

Elaeis Guineensis (Palm) Oil Skin cleansing (cold creams, cleansing 0.002-8%lotions, liquids and pads)

Elaeis Guineensis (Palm) Oil Face and neck creams, lotions and powders 0.008-4%

Elaeis Guineensis (Palm) Oil Body and hand creams, lotions and powders 4-6%

Elaeis Guineensis (Palm) Oil Moisturizing creams, lotions and powders 0.4-3%

Elaeis Guineensis (Palm) Oil Night creams, lotions and powders 3-4%

Elaeis Guineensis (Palm) Oil Paste masks (mud packs) 4-5%

Page 2 of 9


Elaeis Guineensis (Palm) Oil Other skin care preparations 0.9-2%

Elaeis Guineensis (Palm) Kernel Oil Eye lotion 0.8%

Elaeis Guineensis (Palm) Kernel Oil Shampoos (noncoloring) 0.9-23%

Elaeis Guineensis (Palm) Kernel Oil Other manicuring preparations 3%

Elaeis Guineensis (Palm) Kernel Oil Bath soaps and detergents 0.05%

Elaeis Guineensis (Palm) Kernel Oil Shaving cream (aerosol, brushless and 0.05%lather)

Elaeis Guineensis (Palm) Kernel Oil Moisturizing creams, lotions and powders 0.8%

Elaeis Guineensis (Palm) Kernel Oil Other skin care preparations 2%

Hydrogenated Palm Oil Eyebrow pencil 3-5%

Hydrogenated Palm Oil Eyeliner 2-30%

Hydrogenated Palm Oil Eye lotion 0.9%

Hydrogenated Palm Oil Mascara 0.2%

Hydrogenated Palm Oil Colognes and toilet waters 1%

Hydrogenated Palm Oil Face powders 0.4%

Hydrogenated Palm Oil Foundations 8%

Hydrogenated Palm Oil Lipstick 2-30%

Hydrogenated Palm Oil Makeup bases 1%

Hydrogenated Palm Oil Makeup fixatives 0.5%

Hydrogenated Palm Oil Other makeup preparations 25%

Hydrogenated Palm Oil Bath soaps and detergents 2%

Hydrogenated Palm Oil Face and neck creams, lotions and powders 2%

Hydrogenated Palm Oil Body and hand creams, lotions and powders 10%

Hydrogenated Palm Oil Moisturizing creams, lotions and powders 3%

Hydrogenated Palm Oil Paste masks (mud packs) 2%

Hydrogenated Palm Oil Other skin care preparations 3%

Hydrogenated Palm Oil Suntan gels, creams and liquids 1%

Hydrogenated Palm Kernel Oil Eyebrow pencil 2%

Hydrogenated Palm Kernel Oil Eyeliner 7-10%

Hydrogenated Palm Kernel Oil Foundations 0.4%

Page 3 of 9


Hydrogenated Palm Kernel Oil Lipstick 3-13%

Hydrogenated Palm Kernel Oil Bath soaps and detergents 0.9-2%

Hydrogenated Palm Kernel Oil Face and neck creams, lotions and powders 1-5%

Hydrogenated Palm Kernel Oil Body and hand creams, lotions and powders 0.6-3%

Hydrogenated Palm Kernel Oil Moisturizing creams, lotions and powders 2%

Hydrogenated Palm Kernel Oil Night creams, lotions and powders 3%

Hydrogenated Palm Kernel Oil Paste masks (mud packs) 0.6-1%

Hydrogenated Palm Kernel Oil Suntan gels, creams and liquids 0.6%

Palm Acid Bath soaps and detergents 1-4%

Palm Acid Skin cleansing (cold creams, cleansing 17%lotions, liquids and pads)

Palm Kernel Acid Bath soaps and detergents 0.2-3%

Palm Kernel Acid Skin cleansing (cold creams, cleansing 12%lotions, liquids

Potassium Palmate Bath soaps and detergents 0.3-3%

Potassium Palm Kernelate Bath soaps and detergents 0.3-30%

Sodium Palmate Bath soaps and detergents 3-68%

Sodium Palmate Shaving soap (cakes, sticks, etc.) 63%

Sodium Palmate Skin cleansing (cold creams, cleansing 28%lotions, liquids and pads)

Sodium Palm Kernelate Bath soaps and detergents 16-44%

Sodium Palm Kernelate Shaving soaps (cakes, sticks, etc.) 15%

Sodium Palm Kernelate Skin cleansing (cold creams, cleansing 12%lotions, liquids and pads)

Persea Gratissima (Avocado) Oil Bath oils, tablets and salts 0.6-6%

Persea Gratissima (Avocado) Oil Eyeliner 0.1-1%

Persea Gratissima (Avocado) Oil Eye shadow 0.1%

Persea Gratissima (Avocado) Oil Eye lotion 0.05-2%

Persea Gratissima (Avocado) Oil Eye makeup remover 2%

Persea Gratissima (Avocado) Oil Mascara 0.2%

Persea Gratissima (Avocado) Oil Perfumes 8%

Page 4 of 9


Persea Gratissima (Avocado) Oil Powders (dusting and talcum) 0.2%

Persea Gratissima (Avocado) Oil Other fragrance preparations 1%

Persea Gratissima (Avocado) Oil Hair conditioners 0.0001-15%

Persea Gratissima (Avocado) Oil Hair sprays (aerosol fixatives) 0.05%

Persea Gratissima (Avocado) Oil Shampoos (noncoloring) 0.01-1%

Persea Gratissima (Avocado) Oil Tonics, dressings and other hair grooming 41%aids

Persea Gratissima (Avocado) Oil Hair dyes and colors (all types requiring 0.3%caution statement and patch test)

Persea Gratissima (Avocado) Oil Hair rinses (coloring) 0.3%

Persea Gratissima (Avocado) Oil Blushers (all types) 0.2-0.5%

Persea Gratissima (Avocado) Oil Face powders 0.1-0.3%

Persea Gratissima (Avocado) Oil Foundations 0.01-3%

Persea Gratissima (Avocado) Oil Lipstick 0.05-26%

Persea Gratissima (Avocado) Oil Makeup bases 2%

Persea Gratissima (Avocado) Oil Other makeup preparations 0.1%

Persea Gratissima (Avocado) Oil Cuticle softeners 18-19%

Persea Gratissima (Avocado) Oil Nail creams and lotions 2-5%

Persea Gratissima (Avocado) Oil Nail polish and enamel 0.00 1%

Persea Gratissima (Avocado) Oil Other manicuring preparations 34%

Persea Gratissima (Avocado) Oil Bath soaps and detergents 0.02-0.5%

Persea Gratissima (Avocado) Oil Deodorants (underarm) 0.1%

Persea Gratissima (Avocado) Oil Other personal cleanliness products 1-3%

Persea Gratissima (Avocado) Oil Aftershave lotions 0.5%

Persea Gratissima (Avocado) Oil Preshave lotions (all types) 0.00 1%

Persea Gratissima (Avocado) Oil Shaving cream (aerosol, brushless and 0.05%lather)

Persea Gratissima (Avocado) Oil Other shaving preparations 0.8-2%

Persea Gratissima (Avocado) Oil Skin cleansing (cold creams, cleansing 0.003-3%lotions, liquids and pads)

Persea Gratissima (Avocado) Oil Depilatories 0.1%

Page 5 of 9


Persea Gratissima (Avocado) Oil Face and neck creams, lotions and powders 0.01-98%

Persea Gratissima (Avocado) Oil Body and hand creams, lotions and powders 0.01-6%

Persea Gratissima (Avocado) Oil Foot powders and sprays 0.0 1%

Persea Gratissima (Avocado) Oil Moisturizing creams, lotions and powders 0.1-2%

Persea Gratissima (Avocado) Oil Night creams, lotions and powders 0.02-1%

Persea Gratissima (Avocado) Oil Paste masks (mud packs) 0.3-2%

Persea Gratissima (Avocado) Oil Other skin care preparations 0.1-31%

Persea Gratissima (Avocado) Oil Suntan gels, creams and liquids 0.02-2%

Persea Gratissima (Avocado) Oil Indoor tanning preparations 0.0005-0.5%

Hydrogenated Avocado Oil Other hair preparations (noncoloring) 0.5%

Persea Gratissima (Avocado) Oil Eye shadow 0.5%Unsaponifiables

Persea Gratissima (Avocado) Oil Tonics, dressings and other hair grooming 6%Unsaponifiables aids

Persea Gratissima (Avocado) Oil Lipstick 3%Unsaponifiables

Persea Gratissima (Avocado) Oil Skin cleansing (cold creams, cleansing 0.2%Unsaponifiables lotions , liquids and pads)

Oryza Sativa (Rice) Bran Oil Bath oils, tablets and salts 0.2%

Oryza Sativa (Rice) Bran Oil Eyeliner 0.8%

Oryza Sativa (Rice) Bran Oil Eye shadow 0.5%

Oryza Sativa (Rice) Bran Oil Eye lotion 0.5-0.6%

Oryza Sativa (Rice) Bran Oil Hair conditioners 0.2-0.3%

Oryza Sativa (Rice) Bran Oil Hair sprays (aerosol fixatives) 0.1%

Oryza Sativa (Rice) Bran Oil Shampoos (noncoloring) 0.005-0.3%

Oryza Sativa (Rice) Bran Oil Tonics, dressings and other hair grooming 0.02-0.5%aids

Oryza Sativa (Rice) Bran Oil Other hair preparations (noncoloring) 0.3%

Oryza Sativa (Rice) Bran Oil Hair rinses (coloring) 0.3%

Oryza Sativa (Rice) Bran Oil Face powders 0.3%

Oryza Sativa (Rice) Bran Oil Foundations 0.1-1%

Oryza Sativa (Rice) Bran Oil Lipstick 0.1-8%

Page 6 of 9


Oryza Sativa (Rice) Bran Oil Makeup bases 0.4%

Oryza Sativa (Rice) Bran Oil Nail creams and lotions 3-78%

Oryza Sativa (Rice) Bran Oil Nail polish and enamel 0.02%

Oryza Sativa (Rice) Bran Oil Other manicuring preparations 0.1%

Oryza Sativa (Rice) Bran Oil Bath soap and detergents 1%

Oryza Sativa (Rice) Bran Oil Deodorants (underarm) 0.5%

Oryza Sativa (Rice) Bran Oil Other personal cleanliness products 0.0006-6%

Oryza Sativa (Rice) Bran Oil Aftershave lotions 0.5%

Oryza Sativa (Rice) Bran Oil Preshave lotions (all types) 1%

Oryza Sativa (Rice) Bran Oil Skin cleansing (cold creams, cleansing 0.2-0.6%lotions, liquids and pads)

Oryza Sativa (Rice) Bran Oil Depilatories 0.5%

Oryza Sativa (Rice) Bran Oil Face and neck creams, lotions and powders 0.1-27%

Oryza Sativa (Rice) Bran Oil Body and hand creams, lotions and powders 0.5-5%

Oryza Sativa (Rice) Bran Oil Body and hand sprays 0.0003%

Oryza Sativa (Rice) Bran Oil Moisturizing creams, lotions and powders 8%

Oryza Sativa (Rice) Bran Oil Night creams, lotions and powders 4-5%

Oryza Sativa (Rice) Bran Oil Other skin care preparations 0.5-27%

Oryza Sativa (Rice) Germ Oil Bath oils, tablets and salts 3%

Oryza Sativa (Rice) Germ Oil Bubble baths 0.03%

Oryza Sativa (Rice) Germ Oil Eyebrow pencil 0.1%

Oryza Sativa (Rice) Germ Oil Eyeliner 0.1%

Oryza Sativa (Rice) Germ Oil Eye shadow 0.0 1%

Oryza Sativa (Rice) Germ Oil Eye makeup remover 0.01-0.1%

Oryza Sativa (Rice) Germ Oil Mascara 0.1-1%

Oryza Sativa (Rice) Germ Oil Blushers (all types) 0.1%

Oryza Sativa (Rice) Germ Oil Face powders 0.0 1%

Oryza Sativa (Rice) Germ Oil Foundations 0.1%

Oryza Sativa (Rice) Germ Oil Lipstick 0.1-3%

Oryza Sativa (Rice) Germ Oil Makeup bases 0.1%

Page 7 of 9


Oryza Sativa (Rice) Germ Oil Bath soaps and detergents 05%

Oryza Saliva (Rice) Germ Oil Deodorants (underarm) 0.003%

Oryza Sativa (Rice) Germ Oil Other personal cleanliness products 0.003-0.005%

Oryza Sativa (Rice) Germ Oil Skin cleansing (cold creams, cleansing 0.003-0.01%lotions, liquids and pads)

Oryza Sativa (Rice) Germ Oil Face and neck creams, lotions and powders 0.2-3%

Oryza Sativa (Rice) Germ Oil Body and hand creams, lotions and powders 0.02-2%

Oryza Sativa (Rice) Germ Oil Moisturizing creams, lotions and powders 0.01-0.1%

Oryza Sativa (Rice) Germ Oil Night creams, lotions and powders 0.08%

Oryza Saliva (Rice) Germ Oil Paste masks (mud packs) 0.01%

Oryza Sativa (Rice) Germ Oil Other skin care preparations 0.1%

Oryza Sativa (Rice) Germ Oil Suntan gels, creams and liquids 0.01%

Triticum Vulgare (Wheat) Germ Oil Bath oils, tablets and salts 0.5%

Triticum Vulgare (Wheat) Germ Oil Eye shadow 0.02%

Triticum Vulgare (Wheat) Germ Oil Eye lotion 0.1-0.5%

Triticum Vulgare (Wheat) Germ Oil Eye makeup remover 0.0 1%

Triticum Vulgare (Wheat) Germ Oil Mascara 0.05-0.1%

Triticum Vulgare (Wheat) Germ Oil Hair conditioners 0.00 1-0.5%

Triticum Vulgare (Wheat) Germ Oil Hair sprays (aerosol fixatives) 0.0001-00005%

Triticum Vulgare (Wheat) Germ Oil Hair straighteners <1%

Triticum Vulgare (Wheat) Germ Oil Shampoos (noncoloring) 0.00 1-0.5%

Triticum Vulgare (Wheat) Germ Oil Tonics, dressings and other hair grooming 0.00 1-0.5%aids

Triticum Vulgare (Wheat) Germ Oil Other hair preparations (noncoloring) 0.1%

Triticum Vulgare (Wheat) Germ Oil Hair dyes and colors (all types requiring 0.0 1-0.2%caution statement and patch test)

Triticum Vulgare (Wheat) Germ Oil Face powders 0.1%

Triticum Vulgare (Wheat) Germ Oil Foundations 0.001-2%

Triticum Vulgare (Wheat) Germ Oil Lipstick 0.3-5%

Triticum Vulgare (Wheat) Germ Oil Makeup bases 0.1%

Triticum Vulgare (Wheat) Germ Oil Cuticle softeners 1%

Page 8 of 9


Triticum Vulgare (Wheat) Germ Oil Nail creams and lotions 3%

Triticum Vulgare (Wheat) Germ Oil Other manicuring preparations 0.1-28%

Triticum Vulgare (Wheat) Germ Oil Bath soaps and detergents 0.01-0.5%

Triticum Vulgare (Wheat) Germ Oil Other personal cleanliness products 0.2%

Triticum Vulgare (Wheat) Germ Oil Skin cleansing (cold creams, cleansing 0.0 1-2%lotions , liquids and pads)

Triticum Vulgare (Wheat) Germ Oil Depilatories 0.6%

Triticum Vulgare (Wheat) Germ Oil Face and neck creams, lotions and powders 0.00 1-20%

Triticum Vulgare (Wheat) Germ Oil Body and hand creams, lotions and powders 0.3-1%

Triticum Vulgare (Wheat) Germ Oil Moisturizing creams, lotions and powders 0.5-1%

Triticum Vulgare (Wheat) Germ Oil Night creams, lotions and powders 0.08-0.5%

Triticum Vulgare (Wheat) Germ Oil Paste masks (mud packs) 2%

Triticum Vulgare (Wheat) Germ Oil Other skin care preparations 0.1-23%

Triticum Vulgare (Wheat) Germ Oil Suntan gels, creams and liquids 0.04%

Triticum Vulgare (Wheat) Germ Oil Indoor tanning preparations 0.0005%

Triticum Vulgare (Wheat) Germ Oil Face and neck creams, lotions and powders 0.2%Unsaponifiables

Camellia Japonica Seed Oil Eye shadow 0.0 1%

Camellia Japonica Seed Oil Rinses (noncoloring) 0.1%

Camellia Japonica Seed Oil Blushers (all types) 0.01%

Camellia Japonica Seed Oil Lipstick 0.1%

Camellia Japonica Seed Oil Deodorants (underarm) 0.0 1%

Camellia Japonica Seed Oil Other personal cleanliness products 0.1%

Camellia Japonica Seed Oil Moisturizing creams, lotions and powders 0.2%*Ingredients included in the title of the table but not found in the table were included in the concentration of usesurvey, but no uses were reported.

Information collected in 2010Table prepared July 12, 2010

Updated July 21, 2010 (Triticum Aestivum removed)

Page 9 of 9


Personal Care Products CouncilCommitted to Safety,Quality & Innovation

Memorandum

TO: F. Alan Andersen, Ph.D.Director - COSMETIC INGREDiENT REVIEW (Cifi)

FROM: Plant Oil Subcommittee of the Cifi Science and Support Committee

DATE: May 11, 2010

SUBJECT: Comments on the Scientific Literature Review on Vegetable Oil and Related EdibleOils and Derivatives as Used in Cosmetics

A Subcommittee of the CW Science and Support Committee (CIR SSC) reviewed the ScientificLiterature Review (SLR) on Vegetable Oil and Related Edible Oils and Derivatives as Used inCosmetics. The subcommittee is concerned that the SLR contains incorrect information aboutthe chemistry of plant oils, and that the composition information on the oils is still veryincomplete. The subcommittee recommends that the Vegetable Oil and Related Edible Oilsand Derivatives report be revised based on these comments before the CW Expert Panel isgiven the opportunity to review the report. This delay will also allow industry to work onidentifying additional dermal safety data on the ingredients in the report before the report isprovided to the Cifi Expert Panel

In the introduction, please provide a rational as to why the ingredients listed in Table 1 are included inthe report. Please consider including only triglyceride oils (oils, butters and hydrogenated oils)in this report, removing the fatty acids, salts of fatty acids and unsaponifiables. If theunsaponifiable ingredients are left in the report, please provide a rational as to why it isappropriate to include these ingredients in the report, as they generally are neither triglyceridesnor fatty acids.

The Dictionary has misclassified at least three of the ingredients listed in Table 1. AngelicaArchangelica Seed Oil, Apium Graveolens (Celery) Seed Oil, and Daucus Carota Sativa(Carrot) Seed Oil are all essential oils rather than in the chemical class fats and oils. Thechemical class for these ingredients listed in the Dictionary has now been changed to essentialoil. These three ingredients need to be removed from the report. Food Chemical Codex saysthese ingredients are obtained by steam distillation. This is how essential oils are obtained, nottriglyceride oils.

Please consider moving Sclerocarya Birrea Seed Oil, Mangifera Indica (Mango) Seed Oil andMangifera Indica (Mango) Seed Butter to the nut oil report. These two species are in the familyAnacardiaceae, along with other nuts such as cashews and pistachios.

If composition information on an oil cannot be identified in either published or unpublished reports,please consider removing the oil from the report.

1101 17th Street, N.W., Suite 300 Washington, D.C. 20036-4702 202.331.1770 202.331.1969 (fax) www.personalcarecouncil.org CIR Panel Book Page 140

Title - The title of the report should be changed. Edible is not an appropriate descriptor for all of theseoils. Vegetable oils may be a better term to describe them. If the fatty acids andunsaponifiables are left in the report these classes of ingredients should be specificallymentioned in the title.

p.1 - Although common names may be easier, the full INCI names including genus species nameshould be used to avoid confusion (see blackberry seed oil example below).

p.1 - If the fatty acids are left in the report, it should be made clear that “acid” refers to “fatty acid”.p.1 - It is not correct to state the oils are “mixtures of fatty acids”. The oils are mixtures of glyceryl

esters of fatty acids.p.1, 14, Table 2 - It should also be noted that the glyceryl triesters have been reviewed by Cifi and

found safe as used (report published in 2001).p.1 - The Chemistry section needs to be rewritten. These oils are not “a varying assortment of fatty

acids.” As indicated in the fats and oils chemical class definition in the Dictionary, “Fats andOils, as a group, are the glyceryl esters of Fatty Acids (triglycerides)” - a general structure asshown in the Dictionary definition of the fats and oils chemical class would also be helpful.The Chemistry section should note how the hydrogenated oil differs from the oil(hydrogenation reduces or eliminates unsaturation) and define butter (“solid triglyceridewithout any modification”). If the fatty acid and unsaponifiable ingredients are left in thereport, these terms should also be defined. The Dictionary says “unsaponifiables refers to lipidcomponents of natural Fats and Oils which are not hydrolyzed and remain soluble in lipidsolvents after alkaline hydrolysis”. More information about oil chemistry basics can be foundin AAK AarhusKarlshamn Handbook Vegetable Fats and Oils athttp://www.annaochanna.se/pdf/Vegetabilisk%20Handbok.pdf (this is large file that may take along time to open).

p.1, 15-18, Table 3 - Please provide a reason as to why fatty acid composition for some oils areincluded in Table 3 but others are not included. For example the fatty acid composition ofOenothera Biennis (Evening Primrose) Oil is readily available on the internet, e.g.,http://www.vitaplant.ch/plant-oils.pdf and is also found in the PDR for Herbal Medicines (acopy can be found in CJE’s office). Why is the composition of Oenothera Biennis (EveningPrimrose) Oil missing from Table 3? If it has not been done already, please search theAGRICOLA - AGRICultural On Line Access http://www.nal.usda.gov/ag98/ database whichmay have additional information about composition of the plant oils included in this report.Were there criteria for the types of references that were included for composition informationcompared to the types of references that were not included? If only specific references wereconsidered acceptable, the acceptance criteria should be stated.

p.1 - It should be noted that Table 4 includes Food Chemical Codex specifications for oils whereavailable.

p.1 - Please be consistent when talking about vitamin E. In the last paragraph, both vitamin E and -

tocopherol are used.p.2 - As nut oils are not included in this report, “nut” should be removed from the first paragraph of the

Processing section.

Page 2 of 5


p.2, 22-28, Table 5 - The members of the Cifi Expert Panel are accustomed to seeing the cosmetic useinformation by FDA product category. It would be helpful if the CIR Expert Panel memberswere provided with an explanation about which FDA categories fit in each of the categoriespresented in Table 5. For example, From the categories provided in Table 5, it is not clearwhich category includes the FDA bath product categories. Bath products are highly dilutedbefore use. Including them with rinse-off products would be misleading, as the concentrationsof some ingredients in bath products may be higher than in rinse-off products, although actualexposure concentrations will be lower. As FDA uses the term “baby” please continue to use“baby” rather than “infant” - the use of “infant” suggests you mean something different thanwhat is meant by the FDA product category terms. Use information as provided in Table 5 isnot sufficient to complete as risk assessment. A specific product category is needed to estimateexposure.

p.3 - In the second paragraph of this page, please change “particle diameters” to “aerodynamicdiameters” or “da” as used in the previous paragraph.

p.3 - Please add the concentrations of Elaeis Guineensis (Palm) Oil that were practically non- tominimally irritating to rabbit skin. What concentration was non-allergenic in a maximizationstudy? What protocol was used for the in vitro phototoxicity study?

p.4 - In the Olea Europaea (Olive) Fruit Oil section, it would be helpful to note that acetone/olive oil isthe recommended vehicle in murine local lymph node assays (seehttp://iccvam.niehs.nih.gov/docs/immunotox docs/llna/LLNAProt .pdf).

p.4 - What protocol was used in the guinea pig sensitization study by Grover (1962) (reference 20) (itshould be briefly mentioned each time this study is discussed)? Was the composition of the 10-year old oil olive oil measured?

p.4 - What concentrations of Oryza Sativa (Rice) Bran Oil were not irritating or sensitizing to animals?p.4 - What were the concentrations of Triticum Vulgare (Wheat) Germ Oil tested in formulations?p.5 - Please provide a reference that indicates that limonene is a main component of citrus seed oils.

Limonene is a major component of citrus essential oils (from the peel and fruit), but those oilsare not the subject of this report. If the citrus seed oils are not triglycerides they should beremoved from the report. Please see the following reference athttp://www.fshs .org/Proceedings/Password%20Protectedl1963 %2OVol. %2076/249-253 %20(HENDRICKSON).pdf for information on the composition of lemon seed oil.Hendrickson H, Kesterson. 1963. Florida lemon seed oil. Florida Agricultural Experimental

Station Journal Series No. 1726. Florida State Horticultural Society.The following references may also be helpful in determining the composition of the citrus seedoils.Ranganna S, Govindarajan VS, Ramana Ky. 1983. Citrus Fruits Part II Chemistry, technology

and quality evaluation Part A. Chemistry Crit Rev Food Sci Nutr 18(4): 3 13-386Part B. Technology Crit Rev Food Sci Nutr 19(1) 1-98.

p.6 - What concentrations of Oryza Sativa (Rice) Bran Oil and Oryza Sativa (Rice) Germ Oil werenon- to minimally irritating to rabbit eyes? As two oils are mentioned, they should both be inthe subheading.

p.6 - What concentration of Triticum Vulgare (Wheat) Germ Oil was not an ocular irritant?

Page 3 of 5


p.6-7 - IARC states that glycidol is not known to occur as a natural product. IARC did not assess“glycidol fatty esters in refined vegetable oils”, they assessed glycidyl stearate and glycidyloleate and put them in Group 3. If the Cifi Expert Panel determines that the carcinogenicity ofglycidol is important to assessing the safety of the plant oils, tL NTP study (found athttp://ntp.ni ehs.ni h. gov/ntp/htdocs/LT rpts/tr3 74.pdf) should be cited.

p.6-7 - The English summary of the BdR report is athttp://www.bfr.bund.de/cm1245/initial evaluation of the assessment of levels of glycidol fatty acid esters.pdf. They also state “At the present time, the detection of glycidol fatty acidesters in refined vegetable fats has no impact on the fundamental statements on the riskassessment of 3-MCPD fatty acid esters which also occur in these fats.’

p.7 - If “the conversion of glycidol to 3-chloropropanediol was presented as an artifact of the analyticalmethod”, why is this information in the report? Please identify the “crude oil” discussed in thepresentation by Weisshour.

p.7 - If the CIR Expert Panel believes that carcinogenicity is an issue for the oils reviewed in the report,literature searches on carcinogenicity and each oil need to be completed and studies on thecarcinogenicity of the oils need to be added to the report.

p.7 - Aflatoxins are a toxicity issue and not an allergy issue.p.8 - The paragraph concerning protein impurities in oils should be in an impurities section.p.9 - What concentrations of Olea Europea (Olive) Fruit Oil were used in the patch tests (references 42-

49)?p.10, Item 3 - It would helpful if CJR staff would do a more complete job of finding published

information regarding the composition of the oils proposed for inclusion in this report.p.10 - In item 4 of Information Sought, what is meant by “specified concentrations”?p.10, Item 5 - As the oils are triglycerides not mixtures of fatty acids, having irritation and sensitization

testing of individual fatty acids is not necessary if the fatty acids are removed from the report.If the fatty acids are left in the report, Cifi staff should look for published information regardingirritation and sensitization of individual fatty acids. Searching PubMed for Linolenic Acid andsensitization the following was the first reference identified.

Kreilling R, Hollnagal HM, Hareng L, et al. 2008. Comparison of the skin sensitizationpotential of unsaturated compounds as assessed by the murine local lymph nodeassay (LLNA) and the guinea pig maximization test (GPMT). Food ChemicalToxicology 46(6): 1896-1904.

p.10 - Request 6 is not clear. If this review is focused only on the composition of the ingredients andthe dermal effects of the ingredients, why is “any other information that pertains to the safety ofuse in cosmetics” necessary? Requests to industry should reflect the same criteria Cifi staffused for identifying information in the published literature. If all types of safety information areneeded from industry, CIR staff need to go back and identify all the relevant published safetyinformation on these oils. Two examples (identified using the NTP website and ToxNet):there is an NTP study on corn oil and safflower oil that is not mentioned in this report, there is adevelopmental study on perilla oil not in the report (Naito et al. 1990. Shokuhin EiseigakuZasshi 3 1(3): 25 1-254).

p.11 - Please provide a reference for Figure 1.

Page 4 of 5


p.15-18, Table 3 - What is meant by “Araquidic?”? As no oil in the table appears to contain it, it canbe deleted.

p.15-18, Table3, p.19-2!,Table 4 - Rather than arranging these tables in alphabetical order by commonname, these tables should be wTangecl in the same order as tha ingredients are arranged in Table1, alphabetical order by genus species name. Arranging by genus species name will result inspecies of the same genus being presented near each other so similarities among species of thesame genus will be easier to see.

p.16, Table 3, p.20, Table 4 - Reference 60 is for Blackberry Seed Oil (Rubus Fruticosus (Blackberry)Seed Oil) - it is incorrectly called Black Currant Oil in Table 3. Although the company saysthis is an INCI name, it has not been officially assigned and it is not in the Dictionary, nor is iton the list of ingredients included in the report (Table 1). Therefore, the information about thisingredient should be deleted from the report (Tables 3 and 4).

p.18, Table 3, p. 21, Table 4 - As there are several species of strawberries in the Dictionary, the speciesneeds to be identified. Reference 69 indicates that this is Fragaria Ananassa (Strawberry) SeedOil.

p.19-21, Table 4 - Please delete Carrot Seed Oil, Celery Seed Oil and Wild Celery Seed Oil from thistable (and from this report). As discussed above, these essential oils were incorrectly classifiedas fats and oils in the Dictionary. What is the meaning of “*“ with murumuru butter andstrawberry seed oil, and ““ with peach kernel oil?

p.Z2-28, Table 5 - The font used for this table makes it difficult to read.p.29,Table 6 - Please provide references for this table. As ingredients derived from the shea nut are

not included in this report, please delete “shea” from this table. It would be helpful ifinformation about the dietary supplement use for some of these oils, e.g,. Oenothera Biennis(Evening Primrose) Oil, were also provided in this table. If this table is supposed to includeonly non-food, non-cosmetic uses, “substitute for cocoa butter in food” needs to be deletedfrom this table.

Page 5 of 5


GREEN BOOK 3

Nut Oils


AUGUST 30-31, 2010


CIR Expert Panel History with Nut Oils June 2010 - CIR issued a Scientific Literature Review.


Memorandum

To: CIR Expert Panel Members and Liaisons

From: Christina L. Burnett, Scientific Writer/Analyst

Date: July 26, 2010

Subject: Draft Report of the Nut Oil Group

The Scientific Literature Review (SLR) for this group of edible nut oils was announced June 23, 2010. A related SLR on an expansive group of edible plant oils was announced in April of this year, and is to be reviewed by the Panel at this meeting as well. Both reports are taking a slightly new approach to reviewing multiple related ingredients at one time and are including oil ingredients that have previously been reviewed by the CIR Expert Panel, which are designated in italic print.

At the time that the SLR was announced, CIR sought the following additional information:

1. Manufacturing information about oils used in cosmetic formulation, particularly on methods used to remove non-fatty acid components (e.g., glycidol fatty acid esters);

2. Cosmetic grade specifications, if such exist, for oils used in cosmetic formulations.

3. Fatty acid composition for those oils covered in this report (where such information has not been provided or differs from what is presented).

4. Irritation and sensitization testing on cosmetics (finished products) containing specified concentrations of oils covered in this report.

5. Irritation and sensitization testing on those fatty acids present in the oils covered in this report that have previously not been reviewed by CIR.

6. Any other information that pertains to the safety of the use in cosmetics of the oils covered in this report.

Data on cosmetic grade specifications and fatty acid compositions, as well as an HRIPT study on Plukenetia Volubilis Seed Oil have been received from the Personal Care Products Council and are incorporated in this draft report.

Please note that the new use table is being employed in this report. The raw data from which the table was created can be found with the unpublished data.

If the data provided are sufficient for the Panel to assess the safety of these ingredients, a tentative conclusion should be developed regarding their safety in cosmetics, along with a rationale for that conclusion. The report will then be issued as a Tentative Safety Assessment. If additional data are needed, these should be identified and an Insufficient Data Announcement should be issued.

For your convenience, the materials for this report can also be found at http://www.cir-safety.org/aug10.shtml.


Literature Search on Nut Oils

1

Ingredients Toxline PubMed

ChemIDplus HSDB CAplus NTIS HPV Merck USP

Search Date 5/25/2010 5/26/2010 5/26/2010 5/26/2010 5/27/2010 5/27/2010 5/27/2010 CoconutOil √ √ √ √ √ √ √ PeanutOil √ √ √ √ √ √ √ SachaInchiSd √ √ √ √ √ √ √ SheaOil √ √ √ √ √ √ √ ChileanHzlOil √ √ √ √ √ √ √ GalipSdOil √ √ √ √ √ √ √ BrazilSdOil √ √ √ √ √ √ √ KukuiSdOil √ √ √ √ √ √ √ WalnutSdOil √ √ √ √ √ √ √ PistachioSdOil √ √ √ √ √ √ √ PecanSdOil √ √ √ √ √ √ √ MongongoKrnlOil √ √ √ √ √ √ √ MacadamiaSdOil √ √ √ √ √ √ √ HazelSdOil √ √ √ √ √ √ √ CashewSdOil √ √ √ √ √ √ √ SwtAlmondOil √ √ √ √ √ √ √ Ingredients – All Searched with Chemical Composition, Dermal Toxicity, Irritation and Sensitization qualifiers

CoconutOil – (Limited from Panel’s last review to present day) Coconut Oil; 8001-31-8; Cocos Nucifera Oil; 61788-47-4 Coconut Acid; 68938-15-8; Hydrog Coco Acid; 84836-98-6; Hydrog Coco Oil; 61789-30-8; Potassium (Hydrog) Cocoate; 61789-31-9; Sodium (Hydrog) Cocoate; Magnesium Cocoate; Cocos Nucifera Seed OR Coconut Butter

PeanutOil – (Limited from Panel’s last review to present day) Arachis Hypogaea Oil; 8002-03-7; Peanut Oil; 68425-36-5; Hydrog Peanut Oil; 91051-35-3; Peanut Acid; Potassium OR Sodium Peanutate

SachaInchiSdOil – Plukenetia Volubilis Seed Oil; Sacha Inchi Oil

SheaOil – Shea Oil; 68920-03-6; 194043-92-0; Shea Butter; 225234-14-0; Shea Butter Unsap; Butyrospermum Parkii; Vitellaria paradoxa

ChileanHzlOil – Gevuina Avellana Oil; Chilean Hazel Nut Oil

GalipSdOil – Canarium Indicum Seed Oil; Galip Oil

BrazilSdOil – Bertholletia Excelsa Seed Oil; Brazil Nut Oil

KukuiSdOil – Kukui Nut Oil; 8015-80-3;Aleurites Moluccana Seed Oil; Aleurites Moluccanus Bakoly Seed Oil; Hydrogenated Kukui Nut Oil

WalnutSdOil – Walnut Oil; Juglans Regia Seed Oil; 8024-09-7

PistachioSdOil – Pistachio Nut Oil; Pistacia Vera Seed Oil; 90082-81-8; 129871-01-8

PecanSdOil – Pecan Oil; Carya Illinoensis Seed Oil

MongongoKrnlOil – Mongongo Oil; Schinziophyton Rautanenii Kernel Oil

MacadamiaSdOil – Macadamia Nut Oil; Macadamia Integrifolia Seed Oil; Macadamia Ternifolia Seed Oil; 128497-20-1; 129811-19-4; Hydrog. Macadamia Nut Oil; Sodium Macadamiaseedate

HazelSdOil – (Limited from Panel’s last review to present day) Hazelnut Oil; Corylus Americana Seed Oil; Corylus Avellana Seed Oil; Hydrog Hazelnut Oil

CashewSdOil – Cashew Nut Oil; Anacardium Occidentale Seed Oil; 8007-24-7

SwtAlmondOil – (Limited from Panel’s last review to present day) (Sweet) Almond Oil; Prunus Amygdalus (Dulcis) Oil; 8007-69-0; 90320-37-9; Hydrog Sweet Almond Oil (Unsapon.); Sodium Sweet Almondate


Report


Draft Report

Nut Oils as used in Cosmetics

August 30, 2010

The 2010 Cosmetic Ingredient Review Expert Panel members are: Chairman, Wilma F. Bergfeld, M.D., F.A.C.P.; Donald V. Belsito, M.D.; Curtis D. Klaassen, Ph.D.; Daniel C. Liebler, Ph.D.; Ronald A Hill, Ph.D. James G. Marks, Jr., M.D.; Ronald C. Shank, Ph.D.; Thomas J. Slaga, Ph.D.; and Paul W. Snyder, D.V.M., Ph.D. The CIR Director is F. Alan Andersen, Ph.D. This report was prepared by Christina L. Burnett and Monice Fiume, Scientific Analyst/Writers.

© Cosmetic Ingredient Review 1101 17th Street, NW, Suite 412 " Washington, DC 20036-4702 " ph 202.331.0651 " fax 202.331.0088 "

[email protected]


ii

TABLE OF CONTENTS

INTRODUCTION ............................................................................................................................................................................... 1

Chemistry ............................................................................................................................................................................................. 1

Processing .......................................................................................................................................................................... 2

Analytical Methods ............................................................................................................................................................ 2

Impurities ........................................................................................................................................................................... 3

Use ....................................................................................................................................................................................................... 4

Cosmetic ............................................................................................................................................................................ 4

Non-Cosmetic .................................................................................................................................................................... 5

ANIMAL TOXICOLOGY .................................................................................................................................................................. 5

Acute Dermal Toxicity ...................................................................................................................................................... 5

Acute Subcutaneous Toxicity ............................................................................................................................................ 6

Dermal Irritation ................................................................................................................................................................ 6

Arachis Hypogaea (Peanut) Oil..................................................................................................................................... 6

Cocos Nucifera (Coconut) Oil ....................................................................................................................................... 6

Corylus Avellana (Hazel) Seed Oil ................................................................................................................................ 6

Prunus Amygdalus Dulcis (Sweet Almond) Oil ............................................................................................................. 6

Dermal Sensitization .......................................................................................................................................................... 7

Arachis Hypogaea (Peanut) Oil..................................................................................................................................... 7

Cocos Nucifera (Coconut) Oil ....................................................................................................................................... 7



Aleurites Moluccana Seed Oil ....................................................................................................................................... 8

Cocos Nucifera (Coconut) Oil, Hydrogenated Coconut Oil, Coconut Acid .................................................................. 8


CARCINOGENICITY ......................................................................................................................................................................... 8

Anacardium Occidentale (Cashew) Seed Oil ................................................................................................................. 9

CLINICAL ASSESSMENT OF SAFETY .......................................................................................................................................... 9

Irritation/Sensitization/Allergenicity ................................................................................................................................. 9

Arachis Hypogaea (Peanut) Oil................................................................................................................................... 10

Butyrospermum Parkii (Shea) Butter and Unsaponifiables ......................................................................................... 10

Cocos Nucifera (Coconut) Oil and Potassium Cocoate .............................................................................................. 11

Hazel Nut Oil ............................................................................................................................................................... 12

Plukenetia Volubilis ..................................................................................................................................................... 12

Prunus Amygdalus Dulcis (Sweet Almond) Oil ........................................................................................................... 12

Phototoxicity/Photosensitization...................................................................................................................................... 13

Cocos Nucifera (Coconut) Oil and Sodium Cocoate ................................................................................................... 13

Prunus Amygdalus Dulcis (Sweet Almond) Oil ........................................................................................................... 13

Clinical Trials/Case Studies ............................................................................................................................................. 13

Aleurites Moluccana Seed Oil ..................................................................................................................................... 13

Anacardium Occidentale (Cashew) Seed Oil ............................................................................................................... 13

Cocos Nucifera (Coconut) Oil ..................................................................................................................................... 14

Macadamia Nut Oil ..................................................................................................................................................... 14

SUMMARY ....................................................................................................................................................................................... 14

FIGURES AND TABLES ................................................................................................................................................................. 17


1

INTRODUCTION

Oils derived from edible tree and ground nuts have been safely consumed by humans for millennia. While nuts

themselves may cause allergic reactions in certain individuals, the refined oils derived from the nuts generally pose no

significant safety concern following oral exposure, and their general biology is well characterized due to extensive use in

food materials. Various oils have been used on the skin since antiquity. Initially used for anointing in religious ceremonies,

oils and their components have long been used on the skin for cosmetic purposes. This safety assessment will focus solely on

the basic chemistry, manufacturing/production, uses, and irritation and sensitization data available on these oils as they are

used in cosmetic products. The full list of ingredients this report covers, which includes oils, hydrogenated oils,

unsaponifiables, acids, and simple salts, is found in Table 1. For the sake of brevity, the common name of the oil, when

available, will be used throughout this report. While a large number of oils derived from plants are included in this literature

review, there is a commonality in their structure and composition; they all are triglycerides containing various fatty acids and

fatty acid derivatives, the safety of which in cosmetics have been established.

This report includes the macadamia nut ingredients, Macadamia Integrifolia Seed Oil and Macadamia Ternifolia

Seed Oil, which are described in the International Cosmetic Ingredient Dictionary and Handbook.1 The species M.

integrifolia is currently the only species of macadamia nut that is used for oil production. The name M. ternifolia is an old

naming convention for the edible nut that is currently used to describe a non-cultivated, inedible species.2;3 Macadamia

Integrifolia Seed Oil and Macadamia Ternifolia Seed Oil are the same ingredient. The shea plant also has two species names,

Butyrospermum parkii and Vitellaria paradoxa. Only B. parkii (as Butyrospermum Parkii [Shea] Oil or Butter) is the current

naming convention described by the cosmetics industry.

This report includes cosmetic ingredients that have been previously reviewed by the Cosmetic Ingredient Review

Expert Panel. The ingredients, their conclusion, and published citations are found in Table 2. Previously reviewed fatty

acids and glyceryl triesters are also found in Table 2. A report on the safety of vegetable oils and related ingredients is

currently in CIR’s review process.

CHEMISTRY

This group of cosmetic ingredients characterized as fats and oils are the glyceryl esters of fatty acids (triglycerides)

normally found in plant tissues, including those which have been hydrogenated to reduce or eliminate unsaturation.1 Figure 1

provides the general structure of fats and oils. In additions to triglycerides, tree nut oils are also composed of diglycerides,

monoglycerides, free fatty acids, and other minor components, including natural antioxidants and fat-soluble vitamins.4 The

extent to which these components are removed during processing varies. The available information on chemical properties


2

and chemical constituents are found in Tables 3 and 4, respectively. The available fatty acid compositions for the oils in this

report are found in Table 5. The percentage of chemical constituents in individual oil types is dependent on region where the

nut plant is grown, individual cultivars, and plant genetics.5 The nutritional content of these oils varies with oil type, also.

In a study by Lodén and Andersson, shea butter “liquid” contained 9% unsaponifiable lipids, mainly triterpene esters

and sterol esters with cinnamic acid (as determined by high performance liquid chromatography). 6 The unsaponifiable

fraction in this study contained 22% unsaponifiable lipids, out of which 40% consisted of triterpene and sterol esters with

cinnamic acid.

Processing

Oils used in cosmetics are probably produced using the same process used in the food industry. Depending on the

source, oil may be directly expressed from the source (seed or pulp) followed by solvent extraction. Bailey states that the

removal of pigments and polar materials is mandatory for most cosmetic applications.7 The process used for oil refining for

foods may be adequate for this purpose, or additional steps may be required. Special refining methods to yield colorless and

odorless oils are used by the cosmetic industry and include proprietary adsorption chromatography and supercritical fluid

extractions.

The majority of the oils presented in this report are produced either from mechanical extraction or solvent extraction

or a hybrid of both methods, known as prepress solvent extraction.5 In solvent extraction, hexane is the most commonly used

solvent as it is economical and has low toxicity potential when compared to other solvents.

After the initial extraction by methods such as solvent extraction, the crude (degummed) oil is often refined.5 The

first step is treating the oil with caustic soda to neutralize free fatty acids, hydrolyze phosphatides, and remove some colored

pigments and unsaponifiable materials. Soap stock is usually a by-product of this step. The next step involves bleaching the

neutralized oil with activated earth to further absorb pigments. The last major step in refining oil is deodorizing, which

removes all oxidative cleavage products that impart odor or flavor to the oil. Deodorization also removes tocopherols,

sterols, and other minor constituents of free fatty acids and undesirable foreign materials. Figure 2 is a flowchart of the basic

refinement process.

After deodorization, oils can be further processed by hydrogenation, which makes oil more resistant to oxidative and

thermal damage, and by winterization, where oil is slowly cooled to promote formation of crystals that cause cloudiness and

filtered to remove the crystals.

Analytical Methods

Near infrared spectroscopy and gas chromatography have been used, respectively, to phenotype and analyze fatty

acid profiles in shea fat (described as Vitellaria paradoxa, not Butyrospermum parkii).8 The fatty acid composition of


3

hazelnut oil (Corylus avellana, in crude form) has also been analyzed by gas chromatography.9 The triacylglycerol and

diacylglycerol composition oils from hazelnut, pistachio, almond, Brazil nut, and macadamia nuts have been characterized

with high-performance liquid chromatography with atmospheric pressure chemical ionization and UV detection.10 The

triacylglycerol profile of Brazil nut oil has also been quantified using dry matrix-assisted laser desorption/ionization time-of

flight mass spectrometry.11 According to Crevel et al., a validated analytical methodology for establishing the protein content

of oil is needed.12

Impurities

Proteins

Many edible oils are derived from foods that are recognized as potent food allergens. It has been shown that often

an individual that is allergic to a food will generally not react to the refined oil, especially if the oil has been “hot-pressed” or

has undergone more processing.12;13 It should be noted that while the Panel has found a general lack of clinical effects for nut

oils that they have already reviewed,14;15 other researchers have raised concerns about the presence of residual proteins in nut

oils. Olszewski et al. found 0.1-0.2 µg protein per g of peanut oil,16 while Ramazzotti et al. reported finding IgE responsive

residual proteins in peanut oil extracts. 17 The European Medicines Agency (EMEA) Working Party on Herbal Medicinal

Products concluded that peanut products “should be treated as allergenic unless they have an analytically-monitored non-

allergenic specification and a safe maximum daily dose.”18 The EMEA found that threshold concentrations for induction of a

protein contact dermatitis were not available and recommended that “all medications for topical use containing peanut

products should be treated as allergenic.”

Aflatoxin

Aflatoxins are metabolic products of the molds Aspergillus flavus and Aspergillus parasiticus. They are most often

produced in stored agricultural crops (such as peanuts and other nut crops) when growth conditions and genetic requirements

are favorable.19-21 Aflatoxins are identified as B1, B2, G1, G2, M1 and M2 (milk toxins), B2a, and G2a based on fluorescent

color (B = blue, G = green) when separated chromatographically. Aflatoxins B3, R0, P1, Q1, RB1, RB2 and D1 have also been

isolated.20

The International Agency for Research on Cancer (IARC) categorized aflatoxins as group 1 agents, “carcinogenic to

humans”.22;23 Epidemiological studies noted “positive correlation between estimated aflatoxin intake or level of aflatoxin

contamination of market food samples and cooked food and incidence of hepatocellular cancer.” The observations were

supported by positive results in laboratory carcinogenicity and mutagenicity studies. Aflatoxin B1 specifically is recognized

as “one of the most potent environmental mutagens and carcinogens known”.20 Aflatoxin B1 and B2 are the most common

aflatoxins found in peanuts.24


4

The United States government places the following limitations on peanuts to be considered “negative” for aflatoxin:

< 15 ppb for “peanuts which have been certified as meeting edible quality grade requirements” and < 25 ppb for “non-edible

quality categories” (7 CFR Sections 997.30 and 998.200). The FDA has defined the action levels for aflatoxin content in

foods at 20 ppb.25

A study reported that crude peanut oil (obtained by solvent extraction or hydraulic pressing) has reduced aflatoxin

concentration compared to peanut kernels, and that subsequent processing (alkali refining and bleaching) reduces the

concentration still further.14 In one example, processed peanut oil from moldy peanuts (contaminated with 5500 ppb

aflatoxin) had an aflatoxin concentration of < 1ppb. [From CIR assessment on peanut oil, 2001.]

In 50 samples of hazel nuts from Spain, all samples showed fungal contamination, but no aflatoxin contamination.26

Of the 50 fungal strains identified, 25 were aflatoxigenic strains. In 20 hazel nut samples collected in Egypt, however,

aflatoxin (25-175 µg/kg) was reported as a contaminant in 90% of samples. [From CIR assessment on hazel seed oil, 2001.]

Aflatoxin contamination of raw and dried coconut copra has been reported.15 Improper drying, handling, and

storage greatly increase the possibility of contamination by aflatoxins growing on copra. Smoke drying of copra inhibited

aflatoxin formation. [From CIR assessment on coconut oil, 2008.]

USE

Cosmetic

The available use information supplied to the Food and Drug Administration (FDA) by industry as part of the

Voluntary Cosmetic Registration Program (VCRP) on these oil ingredients can be found in Table 6.27 Shea butter has the

most reported uses in cosmetic and personal care products with a total of 1950. A recent survey of use concentrations for shea

butter reports a maximum use concentration of 60% in leave-on products as a cuticle softener, a manicuring application.28 A

survey of use concentrations in the remaining ingredients discussed in this report is currently being conducted by the Personal

Care Products Council (Council). The use concentrations that were reported in previous CIR safety assessments of oils are

also found in Table 5.14;15;26;29 (The year the data were reported is included in parentheses; if no date is available, the data is

current.) Although hazel nut oil (Corylus Americana and Corylus Avellana) were previously reviewed, specific

concentration of use data were not available. One source reported Corylus Avellana seed oil was used up to 100%. Non-

specific hazel nut oil concentration of use ranged from <5% to 50% according to historical FDA data.26

Oils are used in a wide variety of cosmetic products for their skin conditioning, occlusive, emollient, moisturizing

and other properties. The oil ingredients described in this report may be used in hair sprays, and effects on the lungs that may

be induced by aerosolized products containing these ingredients are of concern.


5

The aerosol properties that determine deposition in the respiratory system are particle size and density. The

parameter most closely associated with deposition is the aerodynamic diameter, da, defined as the diameter of a sphere of unit

density possessing the same terminal settling velocity as the particle in question. In humans, particles with an aerodynamic

diameter of ≤ 10µm are respirable. Particles with a da from 0.1 - 10µm settle in the upper respiratory tract and particles with

a da < 0.1 µm settle in the lower respiratory tract.30;31

Particle diameters of 60-80 µm and ≥80 µm have been reported for anhydrous hair sprays and pump hairsprays,

respectively.32 In practice, aerosols should have at least 99% of their particle diameters in the 10 – 110 µm range and the

mean particle diameter in a typical aerosol spray has been reported as ~38 µm.33 Therefore, most aerosol particles are

deposited in the nasopharyngeal region and are not respirable.

None of the oils or their related counterparts described in this report were restricted from use in any way under the

rules governing cosmetic products in the European Union.34

Non-Cosmetic

The primary uses for nut oils are for cooking. Of the nut oils, peanut oil and coconut oil are the world's most widely

consumed.5;35 Non-food, non-cosmetic uses for edible nut oils are found in Table 7.

ANIMAL TOXICOLOGY

Irritation, sensitization and phototoxicity information were not found for all the oils listed in this report. The data

available were reviewed and are summarized below. Information from previous CIR reports on nut oils is identified by

italics.

Acute Dermal Toxicity

Cocos Nucifera (Coconut) Oil

Undiluted hydrogenated coconut oil was applied as a single dose of 3 g/kg to the skin of 12 guinea pigs.15 No

deaths occurred during the 7-d observation period.

Prunus Amygdalus Dulcis (Sweet Almond) Oil

Undiluted sweet almond oil was tested for acute dermal toxicity in guinea pigs.36 The test material was applied

under occlusion to the clipped abraded and intact skin of 12 animals (6 male/6 female) at a dose of 3 g/kg. At 24 hours,

excess material was rinsed off. Observations were made daily for seven days; animals were then killed and necropsied. The

acute dermal LD50 was > 3 g/kg.


6

Acute Subcutaneous Toxicity


Guinea pigs were injected subcutaneously with single or multiple doses of a 10% sweet almond oil emulsion in

saline (1 ml/dose).36 After a single injection, minute oil emboli were found in the lungs of these animals. After six to ten

hours, emboli caused local infiltration of eosinophils in the lung parenchyma. Six days after repeated oil injections,

investigators observed a peripheral blood eosinophilia, which reached a maximum increase of 16.5% by the third week. The

eosinophilia was suggested to be a nonallergic reaction.

Dermal Irritation

Arachis Hypogaea (Peanut) Oil

Undiluted technical grade peanut oil was moderately irritating to rabbits and guinea pig skin and mildly irritating

to rat skin following exposure; there was no indication that the test site was occluded. However, in a 48 h occlusive patch

test using miniature swine, technical grade peanut oil was not irritating.14


Undiluted coconut oil, hydrogenated coconut oil, and coconut acid were non- to minimally irritating to rabbit skin.

In single-insult occlusive patch tests of a 5% aq. solution of a bar soap containing 13% sodium cocoate, scores of 1.6-4.0/8.0

were reported.15

Corylus Avellana (Hazel) Seed Oil

A comedogenicity study was conducted in which 0.1 ml of Corylus Avellana (hazel) nut oil (pH 6) was applied to the

internal fold and the pinna of the right ear of 6 albino rabbits, 5 days per week for 2 weeks.26 Animals were killed at the end

of the study and epidermal samples were obtained from both ears of each rabbit. The samples were examined both by a

magnifying glass and microscopically. No local irritation was noted at the application site. A “slight difference in the

number and size of the pilosebaceous follicles” was noted via magnifying glass. A “slight excess of sebum and a dilation of

the follicles” was noted upon microscopic examination of the treated areas.


Undiluted sweet almond oil was tested for irritancy in groups of 6 male albino rabbits.36 The test material was

applied under occlusion to the clipped intact and abraded dorsal skin of each animal. Twenty-three hours later, patches

were removed; sites were scored at 24 and 48 hours. The Primary Irritation Indices (PIIs) for seven test samples of Sweet

Almond Oil ranged from 0 to 0.18 (maximum score = 8), indicating that this ingredient is practically nonirritating to skin.

Undiluted sweet almond oil and two moisturizer formulations each containing 25% sweet almond oil were tested for

skin irritancy by the following procedure.36 The test material was applied under occlusion to the shaved intact dorsal skin of

groups of 9 female albino rabbits. Patches were removed and sites were scored for erythema at 24 and 72 hours. Undiluted


7

sweet almond oil was nonirritating (PII = 0; maximum score = 4); whereas, the formulations containing 25% sweet almond

oil were minimally irritating (PIIs = 0.28 and 0.72, respectively).

A 60-day cumulative irritation test was used to evaluate the subchronic irritancy of sweet almond oil in rabbits.36

The test material, at concentrations of 10% or 100%, was applied daily to the clipped dorsal skin of groups of 3 albino

rabbits. Sites were scored daily. When tested in 7 separate trials, 100% sweet almond oil produced mean maximum

irritation indices (MMIIs) ranging from 0.34 to 1.34 (maximum score = 8). At a concentration of 10%, MMIIs for this

ingredient ranged from 0 to 0.66. Results indicated that, when applied to the skin over a long period of time, undiluted sweet

almond oil is slightly irritating; whereas, at 10% it is practically nonirritating.

Dermal Sensitization


Hartley and/or Himalayan guinea pigs were used to determine the sensitization potential of peanut oil. Single drops

of a store-bought peanut oil were applied to an area clipped free of hair on the backs of 4 guinea pigs. Applications were

made at 2-6 wk intervals, for a total of 7 applications over a 5-mo period. It appears that the test sites were not covered. The

test sites were scored 24 h after application. Well-defined erythema was considered a positive reaction. None of the animals

had a positive reaction following the initial application. Two animals had positive reactions following application at wks 6

and 12, while one animal had a positive reaction following dosing at wk 12 only.14


In guinea pigs, neither undiluted coconut oil or hydrogenated coconut oil were sensitizers.15


A maximization assay was used to determine the sensitizing potential of sweet almond oil.36 Hartley-strain female

guinea pigs were divided into groups of 10 animals. Each animal received intradermal injections of 50% aqueous Freund’s

complete adjuvant (FCA), 5% sweet almond oil in propylene glycol, and 5% sweet almond oil in 50% FCA into different sites

on epilated dorsal skin. Vehicle control animals were also used. In the dose-range phase of the experiment, each of 50

animals received a single dermal application of 5%, 10%, or 100% sweet almond oil to determine “subirritating” and

“slightly irritating” concentrations to be used for the challenge and booster phases. One week after the induction injection,

100% sweet almond oil was applied occlusively to the treated sites for 48 hours as a topical booster. Animals were

challenged 2 weeks later with 5% sweet almond oil in petrolatum applied topically under occlusion for 24 h. Patches were

then removed and sites were scored 24 and 48 h later. Sweet almond oil was nonsensitizing under these test procedures.


8

Ocular Irritation

Aleurites Moluccana Seed Oil

In in vitro human conjunctival cell assays and in vivo guinea pig Draize tests, Aleurites Moluccana oil was not

cytotoxic and was not an ocular irritant.37 The same authors tested the efficacy of Aleurites Moluccana oil in ocular burn

treatment in vitro and in vivo and did not observe any adverse effects.38

Cocos Nucifera (Coconut) Oil, Hydrogenated Coconut Oil, Coconut Acid

Undiluted coconut oil was instilled into the conjunctival sac of the eyes of each of 2 groups of rabbits (6

rabbits/group). Without subsequent water rinsing of the eyes, maximum irritation scores of 2 and 1 were reported for the 2

treatment groups (max = 110). These results were indicative of minimal eye irritation.15

Undiluted hydrogenated coconut oil was instilled into the eyes of 10 groups of 6 rabbits each in a single dose. The

treated eyes received no subsequent water rinse. In 1 test, mild irritation (6/110) was observed. The eyes appeared normal by

the fourth day. In another study, minimal irritation (2/110) was observed, and the eyes appeared normal by the third day. In

eight tests, negligible or minimal irritation was observed. The eyes were clinically normal by the second day.15

Tests of 2 lipstick formulations containing 10% hydrogenated coconut oil were conducted with 6 albino rabbits

each. Slight conjunctivitis was observed from both formulations (no score provided), but the reaction disappeared by 48 and

24 h, respectively. Undiluted coconut acid was assayed for ocular toxicity in 3 groups of 6 rabbits each. In 2 tests, mild

irritation (8/110 and 9/110) was observed. The eyes were considered normal by the fourth day. In 1 test, minimal irritation

(1/110) was observed, with the eyes returning to normal by the third day.15


The Draize method or a modification of it was used to test the eye irritancy of undiluted sweet almond oil and

cosmetic formulations containing up to 25% sweet almond oil.36 The test material was instilled into one eye of each of 3 to

6 rabbits; the other eye served as an untreated control. Irritation was evaluated 1 h, as well as 1, 2, 3, 4, and 7 days later.

Undiluted sweet almond oil was practically nonirritating or minimally irritating. Formulations containing up to 25% sweet

almond oil were nonirritating to minimally irritating. In most instances, reactions that occurred were limited to conjunctival

irritation, which cleared by the third day of observation.

CARCINOGENICITY

The safety of glycidol fatty acid esters in refined vegetable oils was assessed by IARC. Glycidol was determined to

be a Group2A (probably carcinogenic to humans) chemical while Glycidol Fatty Acid Esters was determined to be a Group 3

(not classifiable as to carcinogenicity to humans) chemical.39;40


9

The Federal Institute for Risk Assessment in Germany released a summary of their initial evaluation of the

assessment of levels of glycidol fatty acid esters detected in refined vegetable fats.41 While acknowledging that the levels of

glycidol that may be released from glycidol fatty acid esters are not known, the evaluation noted that glycidol is classified as

probably carcinogenic to humans. The evaluation was based on findings of the German Chemical and Veterinary Test

Agency (CVUA).

In a presentation by Weisshauer from the CVUA, the conversion of glycidol to 3-chloropropanediol was presented

as an artifact of the analytical method, and it appeared to be the 3-chloropropanediol that was detected its indicative of the

presence of glycidol.42 The levels of 3-chloropropanediol were negligible at the crude oil, degummed, neutralized, and

bleached stages, but levels were significant at the deodorized stage.

Anacardium Occidentale (Cashew) Seed Oil

Singh et al. investigated the modulatory effect of cashew nut oil on antioxidant potential in female Swiss albino

mice in a 120 day skin papillomagenesis study.43 The mice were divided into 4 groups of 15 and 1 group of 10 (vehicle

control). Test groups were as follows: Group I was the vehicle control, receiving 0.1 ml acetone; Group II was the positive

control, receiving a single dose of 7,12-dimethylbenz(a)anthracene (DMBA) (0.005 mg/0.05 ml acetone ) followed by

applications of 2% croton oil 3 times a week until study termination; Group III received a single dose of DMBA followed by

applications of 2.5% cashew nut kernel oil 3 times a week until study termination; Group IV received a single dose of DMBA

followed by applications of 5% cashew nut kernel oil 3 times a week until study termination; and Group V was 5% cashew

nut kernel oil applied until study termination. The oil was applied to the clipped dorsal scapular region that was 2 cm in

diameter. Body weights were recorded at regular intervals. Skin papillomas greater than 1 mm in diameter at the application

sites were recorded weekly and included in the data analysis if they persisted for more than 2 weeks. The positive control

group yielded expected results (86% tumor incidence). No tumors were observed in the vehicle control or the other test

groups. The authors concluded that cashew nut kernel oil did not exhibit any solitary carcinogenic activity.

CLINICAL ASSESSMENT OF SAFETY

Edible oils, including nut oils, are commonly believed to be safe for use on the skin.7 de Groot notes that no

documentation exist to show that high quality edible lipids cause adverse reactions in normal individuals (except for potential

comedogenicity).44 Very few reports of adverse reactions to cosmetic use of edible oils have been reported.

Irritation/Sensitization/Allergenicity

Many edible oils are derived from foods that are recognized as potent food allergens. It has been shown that often

an individual that is allergic to a food will generally not react to the refined oil, especially if the oil has been “hot-pressed” or

has undergone more processing.12;13 A prime example is peanut oil. Peanuts are extremely allergenic to a large population,


10

but reaction to the oil is rare. In the original safety assessment on peanut (Arachis hypogaea) oil, the Expert Panel noted that

the major concern associated with allergic reactions to peanuts is the protein.14 The protein does not partition into the refined

oil, and therefore, oil does not raise the same type of safety concerns as the food containing oil and protein. Crevel et al. also

concluded that chemically refined peanut oil is safe for the majority of peanut allergic individuals.12 They stated that “as

peanut is acknowledged to be one of the most potent food allergens, it is reasonable to extrapolate the conclusions drawn up

for peanut oil to other edible oils.” However, they concede that validated analytical methodology for establishing the protein

content of oil is needed.

In support of the conclusions stated earlier, Crevel et al. also examined the allergenicity of some other oils. Very

few instances of allergic reactions to other major edible oils have been reported. Even sesame oil, which differs from the

other oils in that it is used as a flavorant and therefore is not as refined and expected to contain significantly more protein that

the other edible oils, has had very few reports of allergic reaction.

The preceding paragraphs addressed general allergenicity issues of edible oils. Specific information, where

available, follows and is either summarized from previous CIR reports on edible oils, and is identified by italics, or is new

data and identified by normal text.


The sensitization potential of a topical dermatologic product containing 0.01% fluocinolone and refined peanut oil

was studied in peanut-sensitive children and adults.45 The volunteers for the study included 8 children and 6 adults. The

subjects first underwent a prick skin test with peanut extracts, a solution of 50% glycerin (negative control), a solution o f 1.8

mg.ml histamine phosphate in 50% glycerin (positive control) the complete test product, the product’s vehicle only (without

fluocinolone), and refined peanut oil. Wheals that appeared were measured and recorded after 15 minutes. The subjects

were also patch tested with the complete test product, the product’s vehicle only, and the refined peanut oil. The materials

were applied with Finn chambers on the mid-back, were left in place for 48 h, removed, and observed immediately and after

24 h. Only 1 child had a trace positive reaction to refined peanut oil in the prick skin test. There were no reactions in any of

the subjects to the test product, product vehicle, or the negative control; positive results were observed to the positive control

and the peanut extracts. All subjects had negative patch tests at 48 and 72 h.

Butyrospermum Parkii (Shea) Butter and Unsaponifiables

The effect of a single application of 9 different lipids, including shea butter and fractions of unsaponifiable lipids

from shea butter, on “normal” skin and sodium lauryl sulfate (SLS)-irritated skin was studied in 21 healthy subjects.6 The

shea butter “liquid” sample was obtained from a supplier and the unsaponifiable fraction was obtained through low

temperature crystallization of the supplied sample. The right volar forearm was treated with 50 µl of each test material in 12


11

mm Finn chambers for 48 h. The left volar forearm was treated with 50 µl of 14% aq. SLS for 7 h, rinsed, dried, and then

treated with 50 µl of each test material for 17 h. The treated areas were then washed with mild soap solution, dried, and

examined after 24 h. Visible signs of irritation were assessed and cutaneous blood flow and transepidermal water loss

(TEWL) were measured.

In the normal skin treated with shea butter, barely perceptible erythema was observed in a small number of subjects

(number not reported) 24 h after patching. No irritation from the shea unsaponifiable fraction was observed in any of the

subjects. In the SLS-irritated skin treated with shea butter, 7 subjects had no irritation reaction, 6 had barely perceptible

erythema, 7 had slight erythema, and 1 had moderate erythema. In the SLS-irritated skin treated with shea unsaponifiable

fraction, 9 subjects had no irritation reaction, 8 had barely perceptible erythema, and 2 subjects each had slight and moderate

erythema. No significant differences in cutaneous blood flow or TEWL were observed in shea butter and shea unsaponifiable

fraction when compared to water (control) in either normal or SLS-irritated skin.6

Cocos Nucifera (Coconut) Oil and Potassium Cocoate

A bar soap containing 13% coconut oil was evaluated for skin irritation using standard Draize procedures. One

percent aqueous solutions of the product were applied with occlusive patches to the forearms of 106 panelists over a 3-wk

period. Very minimal skin reactions were recorded, and the researchers concluded the material was not hazardous under

conditions of normal use.15

Bar soaps containing 13% coconut oil were evaluated in a 2-week normal use test. The investigators reported no

unusual irritation response under normal use conditions in 72 panelists.15

Soap chamber tests employing Duhring chambers applied to the forearm were conducted with 8% aqueous

suspension of bar soaps containing 13% coconut oil. One 24-h patch and four 6-h patches were applied over a 5-d period.

In one test with 10 panelists the soap was moderately irritating, and the researchers concluded it was safe under conditions

of normal use. In a second soap chamber test, minimal irritation was observed in a panel of 10 individuals.15

The skin of 40 healthy volunteers and 480 subjects with active skin diseases were patch tested with 15 µL of 5%

aqueous potassium cocoate. Positive responses were observed in 5 subjects (0.9%). Intensities of the positive responses

were not reported; however, 2 subjects had active psoriasis and 3 had active eczema.15

A tanning butter containing 2.5% coconut oil was evaluated using a repeat insult predictive patch test. Nine 24-h

induction patches were applied over a 3-week period. No erythematous reactions were observed in 103 panelists after a

single challenge in the sixth wk of the study.15

Four lipstick formulations containing 10% hydrogenated coconut oil were tested with a single 48-h application on

204 white females. There was no evidence of primary irritation and no indication of sensitization on retests performed 14 d


12

later. 15

Coconut oil was not an allergen at 100% concentration in 12 subjects in a double-blind randomized controlled pilot

study.15

Hazel Nut Oil

A patch testing reference book by de Groot noted that the published literature does not contain recommended test

concentrations concerning hazel nut oil.26 To serve as a guide to the reader, de Groot reported that an unpublished (and at

the time, ongoing) study found no irritant reaction in 1 to 20 patients suffering from or suspected to suffer from cosmetic

product contact allergy who had been patch tested with 30% hazel nut oil in petrolatum.

Plukenetia Volubilis

A human repeat insult patch test (HRIPT) was performed on a lipstick containing 0.51% Plukenetia Volubilis seed

oil in 108 subjects.46 The test material (0.2 g) was applied to the upper back with a ¾ inch square absorbent pad and

occluded. A total of 9 applications were applied for 24 h over a 3-week period during the induction phase. After a 2-week

resting period, a challenge patch was applied to a virgin site for 24 h and the test site was scored at 24 and 72 h post-

application. No reactions were observed and it was concluded that the lipstick containing 0.51% Plukenetia Volubilis seed

oil was not a dermal irritant or sensitizer.


A single insult patch test (SIPT) was used to determine the irritancy of undiluted sweet almond oil.36 The test

material was applied under occlusion to the backs of 101 subjects; 48 h later, the patches were removed and the sites scored.

Sweet almond oil produced no reactions in the test subjects and was determined to be nonirritating.

A HRIPT was used to study the irritancy and sensitizing potential of undiluted sweet almond oil in 52 subjects.36

The test material was applied under occlusion to the back of each subject for 48 h; sites were then read and the compound

reapplied. This procedure was repeated 3 days per week for 3 weeks (9 applications). Following a 2-week rest, 1 or 2

challenge patches were applied to previously untreated skin of each subject. Sites were scored 48 and/or 96 h later.

Undiluted sweet almond oil produced no reactions in any of the 52 subjects and was concluded to be nonirritating and

nonsensitizing.

Repeated insult patch tests were used to study the effects of cosmetic formulations containing 0.1%-25% sweet

almond oil in a total of 6906 subjects.36 Results indicate that these products are practically nonirritating and nonsensitizing

to human skin. Additionally, the Lanman-Maibach 21-day Cumulative Irritancy Assay was used to test the subchronjc

irritancy of a moisturizer containing 25% sweet almond oil. The test material was applied under occlusion to the backs of 10

subjects for 23 hours. Patches were then removed, the site rinsed and scored 1 h later, and the compound reapplied. This


13

procedure was repeated for 21 consecutive days. Of the 10 subjects tested, 7 reacted to 1 or more patches. The total

irritancy score was 14 out of a maximum possible 630.

Phototoxicity/Photosensitization

Cocos Nucifera (Coconut) Oil and Sodium Cocoate

Bar soaps made with 13% coconut oil were tested as a 3% aqueous solution. Patches containing 0.2 ml were

applied 3 times a week for 24 h for a 3-wk period to stripped skin. Sites were exposed to a Wood's lamp for 40 min and a sun

lamp for 15 min following each application. Following a 2-week nontreatment period, duplicate challenge patches were

applied. No evidence of photosensitization was observed in any of the 10 panelists.15

A similar soap prepared as 1 or 3% aqueous solutions was tested on 52 panelists. Occlusive patches containing 0.4

ml of the test solution were applied to the arms 3 times a week for a 3-week period. Sites were exposed to sunlight for 30 min,

24 h after application. Following a 2-week nontreatment period, duplicate challenge patches were applied. Sun exposures

were made 24 h following the challenge application. No evidence of photosensitization was noted.15

Bar soaps made with 13% sodium cocoate were prepared as a 3% aqueous solution. Occlusive patches containing

0.2 ml of the test solution were applied to the tape-stripped backs of 10 volunteers over a 6-week period. After each

application, the treated sites were exposed to an inspectrolamp for 45 min. After UVA exposure, the area was exposed to

about 2/3 of the minimal erythemal dose (MED) from an air-cooled Kromayer lamp. No evidence of phototoxicity was

observed.15


Formulations containing 0.1% - 2.0% sweet almond oil were tested for photosensitization in a total of 764 subjects.

The test material was applied under occlusion to each subject’s back.36 Twenty-four hours later, the patch was removed and

the site scored and irradiated with ultraviolet light from a 150W Xenon Arc Solar Simulator (290-400 nm) at a dose equal to

3 times the individual’s minimal erythema dose (MED). The site was again graded at 72 h and the procedure repeated once.

The products containing 0.1% - 2% sweet almond oil did not manifest photosensitivity in any of the test subjects.

Clinical Trials/Case Studies

Aleurites Moluccana Seed Oil

In an efficacy study of Aleurites Moluccana oil as a topical treatment for psoriasis, 15 patients with mild, stable

plaque psoriasis (less than 15% total body surface area) applied “just enough (oil) to moisten the plaque” 3 times daily for 12

weeks. No side effects or adverse events were reported.47

Anacardium Occidentale (Cashew) Seed Oil

A 37-year-old male resin researcher presented with painful, edematous erythema with bullae on his right leg after

dropping pure cashew nut oil from a bottle on his right thigh.48 He had removed his clothes immediately and thoroughly


14

washed the skin. The erythema developed 10 days after exposure. Patch testing was performed with cashew nut oil 3%

alcohol, cashew nut oil 0.3% alcohol, cashew nut oil 0.03% alcohol, and urushiol 0.01% petrolatum. The patients had a “+”

reaction on day 2 and “++” reactions on days 3 and 4 to the 3% dilution, and “+” reactions to the 0.3% dilution and urushiol

on days 2-4. A “?+” reaction was observed on days 2 and 3 and a “+” reaction was observed on day 4 to the 0.03% dilution.


Coconut oil did not produce adverse effects in several therapeutic studies.15

Macadamia Nut Oil

A case of cheilitis was reported in a 28-year-old woman that had used a lipstick that contained macadamia nut oil

(no species description or concentration of oil were reported).49 When patch tested with the ingredients contained in the

lipstick, the patient had positive reactions to di-isostearyl malate and macadamia nut oil. The patient was told to discontinue

use of lipsticks containing these 2 ingredients and her condition improved with steroid ointment.

SUMMARY

The oils derived from edible nuts are composed of mono-, di-, and triglycerides, free fatty acids and other minor

components, including natural antioxidants and fat-soluble vitamins. The percentage of chemical constituents and nutritional

content of individual oil types is dependent on region where the nut plant is grown, individual cultivars, and plant genetics.

Oils used in cosmetics are likely produced in the same manner as those used in the food industry. Oils may be expressed

through mechanical or solvent extraction. The oils may undergo further refining to remove pigments, odors, unsaponifiable

materials, and other undesirables.

It has been shown that often an individual that is allergic to a food will generally not react to the refined oil. The

CIR Expert Panel has found a general lack of clinical effects for edible nut oils that they have already reviewed; however,

other researchers have raised concerns about the presence of residual proteins in oils, such as peanut and soy. These

ingredients may also contain aflatoxins, a metabolic products of certain molds that are carcinogenic to humans. The FDA

action level for aflatoxin in foods is 20 ppb.

Of the nut oils described in this report, shea butter has the most reported uses in cosmetic and personal care products

with a total of 1950 and is used at a maximum concentration of 60% in leave-on products with manicuring applications. Nut

oils are used in a wide variety of cosmetic products for their skin conditioning, occlusive, emollient, moisturizing, and other

properties. These ingredients may be used in hair spray and other aerosolized products. None of the oils or the related

counterparts described in this report were restricted from use in the European Union.


15

In acute animal studies, undiluted hydrogenated coconut oil and undiluted sweet almond oil were not dermal

toxicants in dermal toxicity studies in guinea pigs at doses of 3 g/kg. In a subcutaneous toxicity study, 10% sweet almond oil

produced nonallergic eosinophilia reactions in guinea pigs.

Undiluted peanut oil was moderately irritating to rabbits and guinea pig skin, mildly irritating in rat skin, and non-

irritating in miniature swine in dermal studies. Undiluted coconut oil, hydrogenated coconut oil, and coconut acid were non-

to minimally irritating in rabbit skin. Corylus Avellana (hazel) nut oil was not irritating to rabbit skin. Sweet almond oil at

25% in formulations was minimally irritating; at 10%, it was practically non-irritating, and at undiluted concentrations, it was

practically non-irritating to slightly irritating.

In animal sensitization studies, store-bought peanut oil produced well-defined erythema only at 12 weeks in a 5

month guinea pig study. Undiluted coconut oil and hydrogenated coconut oil were not sensitizers in guinea pig studies.

Sweet almond oil up to 100% was not sensitizing in a guinea pig study.

Aleurites Moluccana seed oil was not cytoxic or irritating in in vitro and in vivo ocular efficacy studies. Undiluted

coconut oil and undiluted hydrogenated coconut oil were minimal to mild eye irritants in rabbit eyes, while formulations

containing 10% hydrogenated coconut oil produced slight conjunctivitis in rabbit eyes that disappears after 24-48 h.

Undiluted sweet almond oil and formulations containing up to 25% sweet almond oil were nonirritating to minimally

irritating in Draize studies.

Glycidol and glycidol fatty acid esters, possible constituents in refined vegetable and nut oils, were determined to be

Group 2A (probably carcinogenic to humans) and Group 3 (not classifiable as to carcinogenicity to humans) chemicals,

respectively, by IARC. Cashew nut oil did not exhibit solitary carcinogenic activity in a study of the modulatory effect on

the antioxidant potential of this nut oil.

Edible nut oils are believed to be safe for use on the skin and very few reports of adverse reactions have been

reported. While the nuts that these oils are derived from are recognized food allergens, the proteins that are responsible for

allergenic responses do not partition into refined oils.

In 14 peanut-sensitive subjects, only one trace positive reaction was observed to refined peanut oil in a prick skin

test, but no reactions were observed in patch tests. Barely perceptible erythema was observed after exposure to shea butter on

normal skin while no irritation was observed following exposure to shea unsaponifiable fractions.

Bar soaps containing 13% coconut oil, when tested using standard Draize procedures, produced very minimal skin

reactions. In a 2-week normal use test, the bar soaps caused no unusual irritation response. The results of soap chamber tests

of bar soaps were minimal irritation in one study and mild irritation in another. A tanning butter containing 2.5% coconut

oil did not cause erythematous reactions in a 6-week repeat insult predictive patch test. Lipstick containing 10%


16

hydrogenated coconut oil caused no evidence of primary irritation after a single patch application and no indication of

sensitization in retests performed 14 days later. Coconut oil was not an allergen at 100% concentration in 12 subjects in a

double-blind randomized controlled pilot study.

No irritation was observed in patients that were patch tested with 30% hazel nut oil. Irritation and sensitization was

not observed in subjects tested with 0.51% Plukenetia Volubilis seed oil in a HIPT. Undiluted sweet almond oil was non-

irritating and nonsensitizing in SIPT and RIPT studies, and formulations containing 0.1%-25% sweet almond oil were

practically nonirritating and nonsensitizing to human skin.

Bar soaps containing up to 13% coconut oil or sodium cocoate were not photosensitizers in human subjects, nor

were formulations containing 0.1%-2% sweet almond oil.

Aleurites Moluccana seed oil and coconut oil did not produce adverse effects in efficacy studies. Cashew nut oil

and macadamia nut oil caused allergic response in separate case studies.


17

FIGURES AND TABLES

OCR

O

H2C

HC OCR'

O

H2C OCR"

O

-OCR, -OCR', and -OCR" may be the same or dif ferent fatty acid radicals.

Figure 1. General structure of fats and oils.1


18

Figure 2. Basic oil refinement flowchart.5

Crude Oil

Degummed Oil Lecithin Sludge

Alkali Refined Oil Soap Stock

Salad Oil

Cooking Oil Salad and

Cooking Oil Partially

Hydrogenated Oil

Other Fatty Oil

Shortening Stock

Blended Oils

Margarine Stock

Bleached Oil

Salad Oil

Water

Alkali

Deodorization

Deodorization

Deodorization

Deodorization

Deodorization

Deodorization

Activated Earth

H2, Catalyst

Winterization & Deodorization


19

Table 1. Nut oils and their derivatives.

Aleurites Moluccana Seed Oil (CAS No. 8015-80-3) [Kukui]

Aleurites Moluccanus Bakoly Seed Oil Hydrogenated Kukui Nut Oil

Anacardium Occidentale (Cashew) Seed Oil (CAS No. 8007-24-7)

Arachis Hypogaea (Peanut) Oil (CAS No. 8002-03-7)

Peanut Acid (CAS No. 91051-35-3) Potassium Peanutate

Sodium Peanutate

Bertholletia Excelsa Seed Oil [Brazil]

Butyrospermum Parkii (Shea) Oil Butyrospermum Parkii (Shea) Butter (CAS No. 68920-03-6; 194043-92-0)

Butyrospermum Parkii (Shea) Butter Unsaponifiables (CAS No. 194043-92-0; 225234-14-0)

Hydrogenated Shea Butter

Canarium Indicum Seed Oil [Galip] Carya Illinoensis (Pecan) Seed Oil

Cocos Nucifera (Coconut) Oil (CAS No. 8001-31-8)

Coconut Acid (CAS No. 61788-47-4)

Hydrogenated Coconut Acid (CAS No. 68938-15-8) Hydrogenated Coconut Oil (CAS No. 84836-98-6)

Magnesium Cocoate

Potassium Cocoate (CAS No. 61789-30-8)

Potassium Hydrogenated Cocoate Sodium Cocoate (CAS No. 61789-31-9)

Sodium Hydrogenated Cocoate

Cocos Nucifera (Coconut) Seed Butter

Corylus Americana (Hazel) Seed Oil Corylus Avellana (Hazel) Seed Oil

Hydrogenated Hazelnut Oil

Gevuina Avellana Oil [Chilean Hazel]

Juglans Regia (Walnut) Seed Oil (CAS No. 8024-09-7) Macadamia Integrifolia Seed Oil

Macadamia Ternifolia Seed Oil (CAS No. 128497-20-1 or 129811-19-4)

Hydrogenated Macadamia Seed Oil

Sodium Macadamiaseedate Pistacia Vera Seed Oil [Pistachio] (CAS No. 90082-81-8 or 129871-01-8)

Hydrogenated Pistachio Seed Oil

Plukenetia Volubilis Seed Oil [Sacha Inchi]

Prunus Amygdalus Dulcis (Sweet Almond) Oil (CAS No. 8007-69-0 or 90320-37-9) Hydrogenated Sweet Almond Oil

Hydrogenated Sweet Almond Oil Unsaponifiables

Sodium Sweet Almondate

Schinziophyton Rautanenii Kernel Oil [Mongongo]


20

Table 2. Previously reviewed nut oils, fatty acids, and glyceryl triesters.

Ingredients Publication Date Conclusion

Oil Ingredients Arachis Hypogaea (Peanut) Oil (CAS No. 8002-03-7)

IJT 20(S2):65-77, 2001 Safe Hydrogenated Peanut Oil (CAS No. 68425-36-5)

Peanut Acid (CAS No. 91051-35-3)

Cocos Nucifera (Coconut) Oil (CAS No. 8001-31-8)

JACT 5(3):103-121, 1986; CIR Final Report, 2008 Safe

Coconut Acid (CAS No. 61788-47-4) Hydrogenated Coconut Acid (CAS No. 68938-15-8)

Hydrogenated Coconut Oil (CAS No. 84836-98-6)

Magnesium Cocoate

Potassium Cocoate (CAS No. 61789-30-8) Potassium Hydrogenated Cocoate

Sodium Cocoate (CAS No. 61789-31-9)

Sodium Hydrogenated Cocoate

Corylus Americana (Hazel) Seed Oil IJT 20 (S1):15-20, 2001 Insufficient data

Corylus Avellana (Hazel) Seed Oil

Prunus Amygdalus Dulcis (Sweet Almond) Oil (CAS No. 8007-69-0)

JACT 2(5):85-99, 1983; Re-reviewed, not reopened IJT 24 (S1):1-102, 2005 Safe

Fatty Acids

Arachidonic Acid (CAS No. 506-32-1) JACT 12 (5):481-559, 1993 Insufficient data

Hydroxystearic Acid (CAS No. 106-14-9) IJT 18(S1):1-10, 1999 Safe

Lauric Acid (CAS No. 143-07-7)

JACT 6(3):321-401, 1987; Re-reviewed, not reopened IJT 25(2):1-89, 2006

Safe Myristic Acid (CAS No. 544-63-8)

Oleic Acid (CAS No. 112-80-1)

Palmitic Acid (CAS No. 57-10-3)

Stearic Acid (CAS No. 57-11-4)

Glyceryl Triesters

Trilaurin (CAS No. 538-24-9)

IJT 20 (S4):61-94, 2001 Safe

Triarachidin (CAS No. 620-64-4)

Tribehenin (CAS No. 18641-57-1)

Tricaprin (CAS No. 621-71-6)

Tricaprylin (CAS No. 538-23-8)

Trierucin (CAS No. 2752-99-0)

Triheptanoin (CAS No. 620-67-7)

Triheptylundecanoin (CAS No. 105214-66-2)

Triisononanoin

Triisopalmitin (CAS No. 68957-79-9)

Triisostearin (CAS No. 26942-95-0)

Trilinolenin (CAS No. 14465-68-0)

Trimyristin (CAS No. 555-45-3)

Trioctanoin (CAS No. 7360-38-5)

Triolein (CAS No. 122-32-7)

Tripalmitin (CAS No. 555-44-2)

Tripalmitolein (CAS No. 20246-55-3)

Triricinolein (CAS No. 2540-54-7)

Tristearin (CAS No. 555-43-1)

Triundecanoin (CAS No. 13552-80-2)

Glyceryl Triacetyl Hydroxystearate (CAS No. 27233-00-7)

Glyceryl Triacetyl Ricinoleate (CAS No. 101-34-8) Glyceryl Stearate Diacetate


21

Tab

le 3

. Ave

rage

che

mic

al p

rope

rtie

s fo

r cr

ude

and

refin

ed o

ils.

Ale

urite

s M

oluc

anna

See

d O

il [K

ukui

]50

-53

Ana

card

ium

O

ccid

enta

le

(Cas

hew

) S

eed

Oil54

A

rach

is H

ypog

aea

(Pea

nut)

Oil5;

50;5

5-57

Ber

thol

letia

E

xcel

sa S

eed

Oil

[Bra

zil]

54;5

8

But

yros

perm

um

Par

kii (

She

a)

But

ter5;

50;5

9;60

But

yros

perm

um

Par

kii (

She

a) O

il61

Car

ya Il

linoe

nsis

(P

ecan

) S

eed

Oil50

;54;

58

Fre

e fa

tty

aci

ds

(%)

0.1

- 4

; 2 m

ax

(ref

ined

) 0

.2-2

.08

; 0.5

ma

x 1

.0 m

ax

as

olei

c a

cid

< 0.

1 a

s ol

eic

aci

d

Tite

r (◦

C)

26-3

2 4

9-5

4

Mel

ting

poi

nt

(◦C)

32 -

45;

28

-42

(slip

)

Sol

idifi

catio

n p

oin

t (◦

C)

-15

Ref

ract

ive

ind

ex

1.4

73 -

1.4

79

(25◦

C);

1.4

70-1

.48

0 (2

0◦C

) 1.

470

-1.4

72; 1

.462

-1

.464

(4

0◦C)

1.4

73

1.4

68 (

25◦C

) 1

.472

Iod

ine

valu

e 1

.0 m

ax

1.5

ma

x

Sa

pon

ifica

tion

va

lue

146

- 1

66;

13

0-1

75

74

-107

; 80

-106

7

4.2

50

-67;

45

-73

28

- 43

1

00 -

10

5

Per

oxi

de

valu

e (m

eq

O2

/kg

oil)

190

- 1

93;

18

5-2

10

180

-208

; 185

-19

5 1

92.4

1

78-1

90; 1

65-1

90

185

-195

1

90

Sp

ecifi

c gr

avi

ty

5.0

ma

x 0

.22

0.3

9; 5

.0 m

ax

0.1

6 5

.0 m

ax

< 1

0 0

.15

Ap

pea

ran

ce

0.9

20-0

.940

(1

5.5◦C

); 0

.920

-0 .

930

(2

0◦C

)

0.9

10 -

0.9

15

(25◦

/25◦

C);

0.9

12-

0 .9

20 (

20◦

C)

0.9

14 (

25◦C

) 0

.918

(1

5◦C)

0.9

24 (

25◦C

)


22

Tab

le 3

. Ave

rage

che

mic

al p

rope

rtie

s fo

r cr

ude

and

refin

ed n

ut o

ils (

cont

inue

d).

C

ocos

Nuc

ifier

a (C

ocon

ut)

Oil5;

50;6

1 H

azel

See

d O

il55;6

2;63

Jugl

ans

Reg

ia

(Wal

nut)

See

d O

il50;5

5;58

Mac

adam

ia N

ut

Oil55

;58;

64;6

5 P

ista

cia

Ver

a S

eed

Oil

[Pis

tach

io]54

Pru

nus

Am

ygda

lus

(Sw

eet A

lmon

d)

Oil5;

50;5

5;66

;67

Fre

e fa

tty

aci

ds

(%)

< 0

.1%

as

olei

c a

cid

; < 0

.07

% a

s la

uric

aci

d 0

.2 m

ax

as

olei

c a

cid

0.2

- 2

.5

0.5

ma

x; 1

.0 m

ax

as

olei

c a

cid

1.0

ma

x

Tite

r (◦

C)

20

- 24

M

eltin

g p

oin

t (◦C

) 2

2 -

26

Solid

ifica

tion

poi

nt

(◦C

) 9.

0 -

12.

0

Ref

ract

ive

ind

ex

1.4

48 -

1.4

50

(40◦C

) 1

.467

-1.4

74 (

20◦C

) 1

.475

(2

5◦C)

1.4

69; 1

.466

-1.4

70

(20◦

C)

1.4

62 -

1.4

66

(40◦

C);

1.4

67-1

.47

3 ( 2

0◦C

)

Iod

ine

valu

e 0

.6 m

ax

(ref

ined

) S

ap

onifi

catio

n v

alu

e 6

.0 -

11

83

-97

150

- 1

62

78.

3; 6

2-8

2 9

3 -

106

Per

oxi

de

valu

e (m

eq

O2

/kg

oil)

248

- 2

65

187

-197

1

90 -

19

7 1

93.7

; 190

-200

1

83 -

19

7; 1

85

-195

Sp

ecifi

c gr

avi

ty

< 1

0 0

.43;

10.

0 m

ax

0.3

7 0

.36;

10.

0 m

ax

0.2

2 0

.19

Ap

pea

ran

ce

0.9

17 -

0.9

19

(25◦

/15.

5◦C

) 0.

912

-0.9

17

(15

.5◦C

) 0

.917

(2

5◦C)

0.9

15 (

25◦

C);

0.

911

-0.9

18 (

20◦C

)

0.9

13 -

0.9

16

(25◦

C);

0.9

11-0

.92

0 (2

0◦C

)


23

Tab

le 4

. Ave

rage

che

mic

al c

onst

ituen

ts fo

r cr

ude

and

refin

ed o

ils.

Ale

urite

s M

oluc

anna

See

d O

il [K

ukui

]50

-53

Ana

card

ium

O

ccid

enta

le

(Cas

hew

) S

eed

Oil54

A

rach

is H

ypog

aea

(Pea

nut)

Oil5;

50;5

5-57

Ber

thol

letia

E

xcel

sa S

eed

Oil

[Bra

zil]

54;5

8

But

yros

perm

um

Par

kii (

She

a)

But

ter5;

50;5

9;60

But

yros

perm

um

Par

kii (

She

a) O

il61

Car

ya Il

linoe

nsis

(P

ecan

) S

eed

Oil50

;54;

58

Un

sap

onifi

able

m

atte

rs (

%)

0.3

- 1

; 1.0

ma

x <

1.0

3

.0 -

10.

0 <

1.5

0

.35

- 40

α-T

ocoh

ph

erol

(m

g/g)

3

.6

0.0

879

82.

9 1

2.2

γ-T

ocop

her

ol

(mg/

g)

57.

2 0

.060

3 1

16.2

1

68.5

Sq

uale

ne

(mg/

g)

89.

4 0

.098

3 1

377

.8

151

.7

β-S

itost

erol

(m

g/g)

1

768

1.3

6 1

325

.4

1572

.4

Ca

mp

este

rol (

mg/

g)

105

.3

0.1

98

26.

9 5

2.2

Stig

ma

ster

ol

116

.7

0.1

63

577

.5

340

.4

C

ocos

Nuc

ifier

a (C

ocon

ut)

Oil5;

50;6

1 H

azel

See

d O

il55;6

2;63

Jugl

ans

Reg

ia

(Wal

nut)

See

d O

il50;5

5;58

Mac

adam

ia N

ut

Oil55

;58;

64;6

5 P

ista

cia

Ver

a S

eed

Oil

[Pis

tach

io]54

Pru

nus

Am

ygda

lus

(Sw

eet A

lmon

d)

Oil5;

50;5

5;66

;67

Un

sap

onifi

able

m

atte

rs (

%)

< 0

.5

0.5

0

.4 -

1.0

α-T

ocoh

ph

erol

(m

g/g)

0

.31

0.0

21

0.1

22

15.

6 0

.439

5

γ-T

ocop

her

ol

(mg/

g)

0.0

612

0.3

01

Tra

ce

275

.4

0.0

125

Sq

uale

ne

(mg/

g)

0.1

86

0.0

094

0.1

85

91.

4 0

.095

β-S

itost

erol

(m

g/g)

0

.991

1

.13

1.5

1 4

685

.9

2.0

7

Ca

mp

este

rol (

mg/

g)

0.0

667

0.0

51

0.0

733

236

.8

0.0

55

Stig

ma

ster

ol

0.0

381

0.0

555

0.0

383

663

.3

0.0

517


24

T

able

5. F

atty

aci

d co

mpo

sitio

n.

Fat

ty A

cids

C

ocos

Nuc

ifier

a (C

ocon

ut)

Oil15

A

rach

is H

ypog

aea

(Pea

nut)

Oil5;

56;5

7 B

utyr

ospe

rmum

P

arki

i (S

hea)

Oil61

But

yros

perm

um

Par

kii (

She

a)

But

ter5;

59;6

0

Jugl

ans

Reg

ia

(Wal

nut)

See

d O

il68

Mac

adam

ia N

ut

Oil2;

64;6

5

Pru

nus

Am

ygda

lus

(Sw

eet A

lmon

d)

Oil5;

50;6

6;67

;69

Cap

roic

(C

6)

0-1

Cap

rylic

(C

8)

5-9

Cap

ric (

C1

0)

6-1

0 La

uric

(C

12)

44

-52

0.1

- 1

.4

Myr

istic

(C

14)

13

-19

0.7

- 0

.8

1

(C15

)

Pa

lmiti

c (C

16)

8-1

1 7

.2-1

4.2

; 7.0

-16.

0 3

.8-4

.1

5.0

-9.0

; 3.0

-9.0

3

.0 -

7

8.0

- 9

.2; 6

.0-1

2.0

5.5

-6.5

; 6

Pa

lmito

leic

(C

16

:1)

0-1

1

5.6

- 24

.6; 1

2-2

5 H

epta

dec

an

oic

(C17

)

(C17

:1)

Ste

aric

(C

18)

1-3

1

.1-5

; 1.3

-6.5

4

1.2

-56.

8 3

0-4

1; 3

4.0

-50

.0

0.5

- 3

3

.3 -

3.4

; 0.5

-8

2.0

-3.0

Ole

ic (

C18

:1)

5-8

3

3.3

-71.

2; 3

5.0

-72

.0

34.

0-4

6.9

45

-50;

38

.0-5

0.0

9

.0 -

30

54.

8 -

64.2

; 50

-67

70

-77;

69

Lin

olei

c (C

18:2

) T

race

- 2

.5

12

-47.

5; 1

3.0

-43

.0

3.7

-6.5

4

.0-5

; 3.0

-8.0

5

7 -

76

1.5

-5

17

- 20

Li

nol

enic

(C

18

:3)

0

-0.0

4; 0

.6

0.5

ma

x 2

.0 -

16

1.5

- 1

.9; 0

.5 m

ax

0.4

Ara

chid

ic (

C20

)

0.1

7-2

.7; 0

.5-3

.0

1.0

-2.0

3

2.4

- 2

.7; 1

.5-5

Eic

osen

oic

(C2

0:1

)

0.3

3-2

.3; 0

.5-2

.1

2.1

- 3

.1; 1

.5-3

E

icos

adie

noi

c (C

20:2

)

Beh

enic

(C

22)

0

.7-4

.1; 1

.0-5

.0

0.3

- 0

.7

Eru

cic

(C22

:1)

0

.5

(C23

)

Lign

ocer

ic (

C2

4)

0

.2-2

.8; 0

.5-3

.0

*Sh

ad

owin

g id

entif

ies

pre

viou

sly

revi

ew

ed in

gred

ien

ts.


25

T

able

5. F

atty

aci

d co

mpo

sitio

n (c

ontin

ued)

.

Fat

ty A

cids

Car

ya Il

linoe

nsis

(P

ecan

) S

eed

Oil50

;54

Ale

urite

s M

oluc

anna

See

d O

il [K

ukui

]50

;52;

53

Cor

ylus

Ave

llana

(H

azel

) S

eed

Oil9;

62;6

3

Ber

thol

letia

E

xcel

sa S

eed

Oil

[Bra

zil]

54

Pis

taci

a V

era

See

d O

il [P

ista

chio

]54

Ana

card

ium

O

ccid

enta

le

(Cas

hew

) S

eed

Oil54

Cap

roic

(C

6)

Cap

rylic

(C

8)

Cap

ric (

C1

0)

Lau

ric (

C12

)

Myr

istic

(C

14)

Tra

ce

0.0

3 -

0.04

0

.06

0.0

9 0

.07

(C15

)

0.0

1

Pa

lmiti

c (C

16)

3 -

4.3

5

.5; 5

-8

4.9

6 -

5.8;

5-9

1

3.5

7.4

9

.9

Pa

lmito

leic

(C

16

:1)

0.1

0

.5

0.2

; 0.5

-1.0

0

.3

0.7

0

.4

Hep

tad

eca

noi

c (C

17)

0.1

0

.04

- 0.

05

0.2

0

.1

(C17

:1)

0.0

7 -

0.08

Ste

aric

(C

18)

1.8

- 2

6

.7; 0

.1-5

1

.7 -

1.9

; 1.0

-6.0

1

1.8

0.9

8

.7

Ole

ic (

C18

:1)

40.

6 -

79

10.

5; 1

0-3

5 8

0.7

- 82

.6; 6

6-8

5 2

9.1

58.

2 5

7.2

Lin

olei

c (C

18:2

) 1

6 -

50.3

4

8.5;

35

-50

9.8

- 1

1.3;

7-2

5 4

2.8

30.

3 2

0.8

Lin

olen

ic (

C1

8:3

) 0

.7

28.

5; 2

4-4

0 0

.2; 0

.5-0

.6

0.2

0

.4

0.2

Ara

chid

ic (

C20

) T

race

1

.5

0.1

0

.5

0.6

1

Eic

osen

oic

(C2

0:1

) 1

.2

1.0

0

.1 -

0.2

0

.2

0.6

0

.3

Eic

osad

ien

oic

(C20

:2)

Beh

enic

(C

22)

0.2

0

.02

0.1

0

.3

0.4

Eru

cic

(C22

:1)

0.3

0

.01

0.3

0

.6

0.3

(C23

) 0

.01

Lign

ocer

ic (

C2

4)

0

.01

*Sh

ad

owin

g id

entif

ies

pre

viou

sly

revi

ew

ed in

gred

ien

ts.


26

T

able

6.

Fre

quen

cy a

nd c

once

ntra

tion

of u

se a

ccor

ding

to d

urat

ion

and

expo

sure

.14

;15;

26-2

9

No.

of

Use

s C

onc.

of

Use

(%)

No.

of

Use

s C

onc.

of

Use

(%)

No.

of

Use

s C

onc.

of

Use

(%)

No.

of

Use

s C

onc.

of

Use

(%)

No.

of

Use

s C

onc.

of

Use

(%)

S

wee

t Alm

ond

Oil

Hyd

rog.

Sw

eet A

lmon

d O

il S

odiu

m S

wee

t Alm

onda

te

Cas

hew

Oil

Haz

el N

ut O

il (C

. Am

eric

ana)

Fre

quen

cy o

f Use

11

27

0.00

4 -

76

21

4

10

10

Le

ave

-On

801

0

.004

- 7

6 1

3

4

9

9

Rin

se O

ff

326

0

.01

- 2

8

0

1

1

Eye

2

8 0

.4

0 0

0 0

Pos

sib

le In

gest

ion

5

5 0

.5

1 0

0 0

Inh

ala

tion

18

1 -

3

0 0

0 0

Der

ma

l 9

86

0.0

04 -

11

15

4 9

10

Deo

dor

an

t (u

nder

arm

) 2

0.0

04

0 0

0 0

Ha

ir -

Non

-co

lorin

g 1

17

0.3

- 3

6

0 1

0

Ha

ir -

Col

orin

g 2

0.1

0

0 0

0 N

ail

13

1 -

76

0 0

0 0

Muc

ous

Mem

bra

ne

134

0

.01

- 0.

1 2

0 0

1

Bab

y 1

8 -

0 0

0 0

(2

002

con

c.)

H

azel

Nut

Oil

(C. A

vella

na)

Mac

adam

ia In

tegr

ifolia

Nut

Oil

Mac

adam

ia N

ut O

il M

acad

amia

Ter

nifo

lia N

ut O

il S

chin

ziop

hyto

n R

auta

neni

i K

erne

l Oil

Fre

quen

cy o

f Use

15

0 up

to 1

00

41

20

8

533

6

Le

ave

-On

130

25

1

91

4

71

3

R

inse

Off

20

1

6

17

6

2

3

Eye

9

4 2

2 1

6 0

Pos

sib

le In

gest

ion

2

4 1

1 3

3 0

Inh

ala

tion

0 0

2 1

2 0

Der

ma

l 1

47

36

170

4

93

3 D

eod

ora

nt

(und

era

rm)

0 0

0 0

0

Ha

ir -

Non

-co

lorin

g 2

2 9

33

3

Ha

ir -

Col

orin

g 0

0 0

3 0

Na

il 1

0 2

8 1

0 M

ucou

s M

emb

ran

e 3

11

1 1

4 0

Bab

y 1

0 0

4 0

(200

1 co

nc.

)


27

T

able

6.

Fre

quen

cy a

nd c

once

ntra

tion

of u

se a

ccor

ding

to d

urat

ion

and

expo

sure

(co

ntin

ued)

.14

;15;

26-2

9

No.

of

Use

s C

onc.

of

Use

(%

) N

o. o

f U

ses

Con

c. o

f U

se (%

) N

o. o

f U

ses

Con

c. o

f U

se (%

) N

o. o

f U

ses

Con

c. o

f U

se(%

) N

o. o

f U

ses

Con

c. o

f U

se (%

)

P

ecan

Nut

Oil

Pis

tach

io N

ut O

il P

luke

netia

Vol

ubili

s S

eed

Oil

Wal

nut O

il C

ocon

ut O

il

Fre

quen

cy o

f Use

8

15

8

13

15

798

0.00

01 -

80

Le

ave

-On

7

105

12

1

2

372

0

.005

- 8

0

Rin

se O

ff

1

53

1

3

4

26

0.0

001

- 4

1

Eye

1

7 1

1 2

5 0

.01

- 80

P

ossi

ble

Inge

stio

n

0 6

3 0

44

0.2

- 5

1 In

ha

latio

n 0

0 0

0 1

0 0

.1 -

26

Der

ma

l 8

133

1

3 1

4 5

48

0.0

005

- 8

0 D

eod

ora

nt

(und

era

rm)

0 0

0 0

0 0

.1 -

16

Ha

ir -

Non

-co

lorin

g 0

18

0 1

176

0

.000

1 -

13

Ha

ir -

Col

orin

g 0

0 0

0 6

9 -

Na

il 0

2 0

0 5

0.0

05 -

2

Muc

ous

Mem

bra

ne

1 2

7 0

2 1

76

0.0

005

- 4

1 B

aby

0 3

0 0

15

0.0

1 -

0.3

(200

8 co

nc.

)

H

ydro

g. C

ocon

ut O

il C

ocon

ut A

cid

Hyd

rog.

Coc

onut

Aci

d

Mag

nesi

um C

ocoa

te

Pot

assi

um C

ocoa

te

Fre

quen

cy o

f Use

10

5 0.

001

- 50

14

1 0.

03 -

14

0 6

- 10

9

- 40

0.

003

- 40

Le

ave

-On

79

0.0

01 -

50

17

- 0

6 0

- 0

0.3

Rin

se O

ff

26

0.0

01 -

39

124

0

.03

- 14

0

10

9 -

40

0.0

03 -

40

Eye

7

0.2

- 2

2 1

- 0

- 0

- 0

- P

ossi

ble

Inge

stio

n

10

0.7

- 2

9 0

- 0

- 0

- 0

- In

ha

latio

n 0

0.3

- 0

.7

0 -

0 -

0 -

0 -

Der

ma

l 1

02

0.0

6 -

50

140

0

.04

- 14

0

6 -

10

9 -

38

0.3

- 4

0 D

eod

ora

nt

(und

era

rm)

0 -

0 -

0 -

0 -

0 0

.3

Ha

ir -

Non

-co

lorin

g 3

0.0

01 -

2

1 0

.03

- 0.

3 0

- 0

- 2

15

Ha

ir -

Col

orin

g 0

0.5

- 0

.6

0 -

0 -

0 -

0 0

.003

N

ail

0 0

.8 -

25

0 -

0 -

0 -

0 -

Muc

ous

Mem

bra

ne

18

0.5

- 3

9 1

01

0.0

4 -

14

0 -

9 -

26

0.2

- 4

0 B

aby

1 2

- 5

0 1

- 0

- 0

- 0

-

(200

8 co

nc.

)

(200

8 co

nc.

)

(200

8 co

nc.

)

(200

8 co

nc.

)

(200

8 co

nc.

)


28

T

able

6.

Fre

quen

cy a

nd c

once

ntra

tion

of u

se a

ccor

ding

to d

urat

ion

and

expo

sure

(co

ntin

ued)

.14

;15;

26-2

9

No.

of

Use

s C

onc.

of

Use

(%

) N

o. o

f U

ses

Con

c. o

f U

se

(%)

No.

of

Use

s C

onc.

of

Use

(%

) N

o. o

f U

ses

Con

c. o

f U

se

(%)

No.

of

Use

s C

onc.

of

Use

(%

)

Sod

ium

Coc

oate

P

eanu

t Oil

Hyd

rog.

Pea

nut O

il S

hea

But

ter

She

a B

utte

r O

il

Fre

quen

cy o

f Use

34

0 1

- 52

74

<2

5 -

>50

12

1950

0.

0005

– 6

0 22

0.

01 –

15

Le

ave

-On

12

- 5

3

12

1

596

0.0

01 -

60

16

0.0

1 –

15

Rin

se O

ff

328

1

- 5

2 2

1

0

354

0

.000

5 -

30

6 0

.6 –

1

Eye

0

- 4

0 1

08

0.1

- 8

1

- P

ossi

ble

Inge

stio

n

0 -

0 0

128

0

.5 -

26

0 1

5 In

ha

latio

n 0

- 2

0 1

7 0

.001

- 3

0

- D

erm

al

269

1

- 5

2 5

3 1

2 1

724

0.0

01 -

45

22

0.6

– 1

5 D

eod

ora

nt

(und

era

rm)

0 -

0 0

2 1

0 -

Ha

ir -

Non

-col

orin

g 7

1 2

21

0 2

10

0.0

005

- 5

0

-

Ha

ir -

Col

orin

g 0

- 0

0 4

- 0

- N

ail

0 -

0 0

7 0

.01

- 60

0

0.0

1 –

1 M

ucou

s M

emb

ran

e 2

41

1 -

52

2 0

114

0

.003

- 5

6

0.6

– 1

B

aby

5 -

0 0

24

0.0

1 -

5 0

-

(200

8 co

nc.

)

(200

1 co

nc.

)

2

010

con

c.

2

010

con

c.

H

ydro

g. S

hea

But

ter

She

a B

utte

r U

nsap

on.

Ale

urite

s S

eed

Oil

Ber

thol

letia

Exc

elsa

Oil

Gev

uina

Ave

llana

Oil

Fre

quen

cy o

f Use

4

1 38

0.

06 –

3

141

55

5 Le

ave

-On

2 1

33

0.0

6 –

3 8

7

18

5

Rin

se O

ff

2 1

5 2

54

3

7

0 E

ye

0 -

7 0

.2 –

0.7

6

1 0

Pos

sib

le In

gest

ion

0

- 2

1 –

3

1 0

0 In

ha

latio

n 0

- 0

- 1

5 1

0 D

erm

al

4 1

33

0.0

6 –

3 7

6 2

9 5

Deo

dor

an

t (u

nder

arm

) 0

- 0

- 0

0 0

Ha

ir -

Non

-col

orin

g 0

- 5

2 5

8 1

2 0

Ha

ir -

Col

orin

g 0

- 0

- 0

14

0 N

ail

0 -

0 -

4 0

0 M

ucou

s M

emb

ran

e 2

- 0

- 1

1 1

0 0

Bab

y 0

- 1

- 0

0 0

201

0 c

onc.

201

0 c

onc.


29

Table 7. Non-food, non-cosmetic uses of edible oils.5;51;68-72

Oil Use

Almond Pharmaceutical, energy source

Cashew Folk remedies

Coconut Lubricants, hydraulic fluid, paints, synthetic rubber, plastics, illumination

Kukui Wood preservative, varnishes, paint oil, illumination, soap making, waterproofing paper, rubber substitute, insulating material

Peanut Pharmaceutical, soap making, lubricants, emulsions for insect control, diesel engine fuel

Shea Illumination

Walnut Paints, soap making


30

Reference List

(1) Gottschalck TE, Bailey JE. International Cosmetic Ingredient Dictionary and Handbook. 13th. 2010. Washington, DC, Personal Care Products Council.

Ref Type: Edited Book

(2) Center for New Crops & Plant Products. Macadamia integrifolia Maiden & Betche and Macadamia tetraphylla L. Johnson. NewCROP . 1-7-1998. Department of Horticulture and Landscape Architecture, 625 Agriculture Mall Drive, West Lafayette, IN 47907-2010, Purdue University. 5-20-2010.

Ref Type: Online Source

(3) Storey W. The Ternifolia group of Macadamia species. Pacific Science 1965;19:507-514.

(4) Miraliakbari H, Shahidi F. Oxidative stability of tree nut oils. J Agric Food Chem 2008;56:4751-4759.

(5) Salunkhe D, Chavan J, Adsule R, Kadam S. World Oilseeds: Chemistry, Technology, and Utilization. New York: Van Nostrand Reinhold, 1992.

(6) Loden M, Andersson A. Effect of topically applied lipids on surfactant-irritated skin. Br J Dermatol 1996;134:215-220.

(7) Bailey's Industrial Oil & Fat Products. John Wiley & Sons., 1996.

(8) Davrieux F, Allal F, Piombo G et al. Near infrared spectroscopy for high-throughput characaterization shea tree (Vitellaria paradoxa) nut fat profiles. J Agric Food Chem 2010.

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31

(17) Ramazzotti M, Mulinacci N, Pazzagli L et al. Analytic investigations on protein content in refined seed oils: implications in food allergy. Food Chem Toxicol 2008;46:3383-3388.

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(46) Consumer Product Testing Co. Repeated insult patch test of a lipstick containing 0.509847% Plukentia Volubilis Seed Oil. Experiment reference number: C08-5394.06. Unpublished data. 2008. Consumer Product Testing Co.

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33

Ref Type: Generic

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34

(70) Center for New Crops & Plant Products. Anacardium occidentale L. NewCROP . 12-22-1997. Department of Horticulture and Landscape Architecture, 625 Agriculture Mall Drive, West Lafayette, IN 47907-2010, Purdue University. 5-20-2010.


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Data


2010 FDA Frequency of Use Raw Data

01A - Baby Shampoos PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 1

01B - Baby Lotions, Oils, Powders, and Creams PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 13

01C - Other Baby Products PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 4

02A - Bath Oils, Tablets, and Salts PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 25

02B - Bubble Baths PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 10

02D - Other Bath Preparations PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 6

03A - Eyebrow Pencil PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 1

03B - Eyeliner PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 2

03C - Eye Shadow PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 1

03D - Eye Lotion PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 5

03E - Eye Makeup Remover PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 3

03F - Mascara PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 9

03G - Other Eye Makeup Preparations PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 7

04C - Powders (dusting and talcum, excluding aftershave talc) PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 2

04E - Other Fragrance Preparation PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 4

05A - Hair Conditioner PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 40

05B - Hair Spray (aerosol fixatives) PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 8

05F - Shampoos (non-coloring) PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 27

05G - Tonics, Dressings, and Other Hair Grooming Aids PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 29

05I - Other Hair Preparations PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 12

06G - Hair Bleaches PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 2

07B - Face Powders PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 1

07C - Foundations PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 3

07E - Lipstick PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 55

07F - Makeup Bases PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 1

07I - Other Makeup Preparations PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 9

08B - Cuticle Softeners PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 9

08C - Nail Creams and Lotions PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 1

08F - Nail Polish and Enamel Removers PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 1

08G - Other Manicuring Preparations PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 2

10A - Bath Soaps and Detergents PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 64

10B - Deodorants (underarm) PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 2

10E - Other Personal Cleanliness Products PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 29

11A - Aftershave Lotion PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 5

11D - Preshave Lotions (all types) PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 1

11E - Shaving Cream PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 7

11F - Shaving Soap PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 1

11G - Other Shaving Preparation Products PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 3

12A - Cleansing PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 59

12B - Depilatories PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 11

12C - Face and Neck (exc shave) PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 45

12D - Body and Hand (exc shave) PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 200

12E - Foot Powders and Sprays PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 4

12F - Moisturizing PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 266

12G - Night PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 22

12H - Paste Masks (mud packs) PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 25

12I - Skin Fresheners PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 7

12J - Other Skin Care Preps PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 72

13A - Suntan Gels, Creams, and Liquids PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 5

13B - Indoor Tanning Preparations PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 5

13C - Other Suntan Preparations PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL 1



02A - Bath Oils, Tablets, and Salts BITTER ALMOND OIL 2

05A - Hair Conditioner BITTER ALMOND OIL 8

05F - Shampoos (non-coloring) BITTER ALMOND OIL 5

05I - Other Hair Preparations BITTER ALMOND OIL 1

10A - Bath Soaps and Detergents BITTER ALMOND OIL 2

12A - Cleansing BITTER ALMOND OIL 1

12D - Body and Hand (exc shave) BITTER ALMOND OIL 3

12F - Moisturizing BITTER ALMOND OIL 4

12G - Night BITTER ALMOND OIL 1

12I - Skin Fresheners BITTER ALMOND OIL 1

12J - Other Skin Care Preps BITTER ALMOND OIL 3

02A - Bath Oils, Tablets, and Salts HYDROGENATED SWEET ALMOND OIL 1

05A - Hair Conditioner HYDROGENATED SWEET ALMOND OIL 1

05F - Shampoos (non-coloring) HYDROGENATED SWEET ALMOND OIL 3

05G - Tonics, Dressings, and Other Hair Grooming Aids HYDROGENATED SWEET ALMOND OIL 2

07E - Lipstick HYDROGENATED SWEET ALMOND OIL 1

10A - Bath Soaps and Detergents HYDROGENATED SWEET ALMOND OIL 1

11F - Shaving Soap HYDROGENATED SWEET ALMOND OIL 1

12C - Face and Neck (exc shave) HYDROGENATED SWEET ALMOND OIL 1

12D - Body and Hand (exc shave) HYDROGENATED SWEET ALMOND OIL 2

12F - Moisturizing HYDROGENATED SWEET ALMOND OIL 7

12H - Paste Masks (mud packs) HYDROGENATED SWEET ALMOND OIL 1

12J - Other Skin Care Preps SODIUM SWEET ALMONDATE 4

05E - Rinses (non-coloring) ANACARDIUM OCCIDENTALE (CASHEW) SEED OIL 1

12C - Face and Neck (exc shave) ANACARDIUM OCCIDENTALE (CASHEW) SEED OIL 3

12D - Body and Hand (exc shave) ANACARDIUM OCCIDENTALE (CASHEW) SEED OIL 4

12F - Moisturizing ANACARDIUM OCCIDENTALE (CASHEW) SEED OIL 2

10E - Other Personal Cleanliness Products CORYLUS AMERICANA (HAZEL) SEED OIL 1

12C - Face and Neck (exc shave) CORYLUS AMERICANA (HAZEL) SEED OIL 4

12D - Body and Hand (exc shave) CORYLUS AMERICANA (HAZEL) SEED OIL 2

12G - Night CORYLUS AMERICANA (HAZEL) SEED OIL 1

12J - Other Skin Care Preps CORYLUS AMERICANA (HAZEL) SEED OIL 1

13C - Other Suntan Preparations CORYLUS AMERICANA (HAZEL) SEED OIL 1

01B - Baby Lotions, Oils, Powders, and Creams CORYLUS AVELLANA (HAZEL) SEED OIL 1

02A - Bath Oils, Tablets, and Salts CORYLUS AVELLANA (HAZEL) SEED OIL 2

03D - Eye Lotion CORYLUS AVELLANA (HAZEL) SEED OIL 1

03G - Other Eye Makeup Preparations CORYLUS AVELLANA (HAZEL) SEED OIL 8

05F - Shampoos (non-coloring) CORYLUS AVELLANA (HAZEL) SEED OIL 1

05I - Other Hair Preparations CORYLUS AVELLANA (HAZEL) SEED OIL 1

07C - Foundations CORYLUS AVELLANA (HAZEL) SEED OIL 1

07E - Lipstick CORYLUS AVELLANA (HAZEL) SEED OIL 2

08G - Other Manicuring Preparations CORYLUS AVELLANA (HAZEL) SEED OIL 1

10E - Other Personal Cleanliness Products CORYLUS AVELLANA (HAZEL) SEED OIL 1

12A - Cleansing CORYLUS AVELLANA (HAZEL) SEED OIL 5

12C - Face and Neck (exc shave) CORYLUS AVELLANA (HAZEL) SEED OIL 41

12D - Body and Hand (exc shave) CORYLUS AVELLANA (HAZEL) SEED OIL 30

12F - Moisturizing CORYLUS AVELLANA (HAZEL) SEED OIL 22

12G - Night CORYLUS AVELLANA (HAZEL) SEED OIL 7

12H - Paste Masks (mud packs) CORYLUS AVELLANA (HAZEL) SEED OIL 10

12J - Other Skin Care Preps CORYLUS AVELLANA (HAZEL) SEED OIL 14

13A - Suntan Gels, Creams, and Liquids CORYLUS AVELLANA (HAZEL) SEED OIL 1

13C - Other Suntan Preparations CORYLUS AVELLANA (HAZEL) SEED OIL 1

02A - Bath Oils, Tablets, and Salts MACADAMIA INTEGRIFOLIA SEED OIL 1

03F - Mascara MACADAMIA INTEGRIFOLIA SEED OIL 3

03G - Other Eye Makeup Preparations MACADAMIA INTEGRIFOLIA SEED OIL 1

05A - Hair Conditioner MACADAMIA INTEGRIFOLIA SEED OIL 1

05G - Tonics, Dressings, and Other Hair Grooming Aids MACADAMIA INTEGRIFOLIA SEED OIL 1

07E - Lipstick MACADAMIA INTEGRIFOLIA SEED OIL 4

10A - Bath Soaps and Detergents MACADAMIA INTEGRIFOLIA SEED OIL 1

10E - Other Personal Cleanliness Products MACADAMIA INTEGRIFOLIA SEED OIL 9

12A - Cleansing MACADAMIA INTEGRIFOLIA SEED OIL 4

12D - Body and Hand (exc shave) MACADAMIA INTEGRIFOLIA SEED OIL 7

12F - Moisturizing MACADAMIA INTEGRIFOLIA SEED OIL 8

13B - Indoor Tanning Preparations MACADAMIA INTEGRIFOLIA SEED OIL 1

02A - Bath Oils, Tablets, and Salts MACADAMIA NUT OIL 1



03B - Eyeliner MACADAMIA NUT OIL 8

03C - Eye Shadow MACADAMIA NUT OIL 9

03D - Eye Lotion MACADAMIA NUT OIL 1

03F - Mascara MACADAMIA NUT OIL 1

03G - Other Eye Makeup Preparations MACADAMIA NUT OIL 3

04E - Other Fragrance Preparation MACADAMIA NUT OIL 2

05A - Hair Conditioner MACADAMIA NUT OIL 3

05F - Shampoos (non-coloring) MACADAMIA NUT OIL 4

05G - Tonics, Dressings, and Other Hair Grooming Aids MACADAMIA NUT OIL 1

05I - Other Hair Preparations MACADAMIA NUT OIL 1

07A - Blushers (all types) MACADAMIA NUT OIL 7

07B - Face Powders MACADAMIA NUT OIL 3

07E - Lipstick MACADAMIA NUT OIL 11

07F - Makeup Bases MACADAMIA NUT OIL 11

07G - Rouges MACADAMIA NUT OIL 5

07I - Other Makeup Preparations MACADAMIA NUT OIL 6

08A - Basecoats and Undercoats MACADAMIA NUT OIL 1

08E - Nail Polish and Enamel MACADAMIA NUT OIL 27

12A - Cleansing MACADAMIA NUT OIL 5

12C - Face and Neck (exc shave) MACADAMIA NUT OIL 24

12D - Body and Hand (exc shave) MACADAMIA NUT OIL 18

12F - Moisturizing MACADAMIA NUT OIL 31

12G - Night MACADAMIA NUT OIL 7

12H - Paste Masks (mud packs) MACADAMIA NUT OIL 3

12I - Skin Fresheners MACADAMIA NUT OIL 1

12J - Other Skin Care Preps MACADAMIA NUT OIL 6

13A - Suntan Gels, Creams, and Liquids MACADAMIA NUT OIL 3

13B - Indoor Tanning Preparations MACADAMIA NUT OIL 5



01B - Baby Lotions, Oils, Powders, and Creams MACADAMIA TERNIFOLIA SEED OIL 4

02A - Bath Oils, Tablets, and Salts MACADAMIA TERNIFOLIA SEED OIL 2

03B - Eyeliner MACADAMIA TERNIFOLIA SEED OIL 4

03D - Eye Lotion MACADAMIA TERNIFOLIA SEED OIL 8

03F - Mascara MACADAMIA TERNIFOLIA SEED OIL 3

03G - Other Eye Makeup Preparations MACADAMIA TERNIFOLIA SEED OIL 1

04E - Other Fragrance Preparation MACADAMIA TERNIFOLIA SEED OIL 5

05A - Hair Conditioner MACADAMIA TERNIFOLIA SEED OIL 7

05B - Hair Spray (aerosol fixatives) MACADAMIA TERNIFOLIA SEED OIL 5

05F - Shampoos (non-coloring) MACADAMIA TERNIFOLIA SEED OIL 6

05G - Tonics, Dressings, and Other Hair Grooming Aids MACADAMIA TERNIFOLIA SEED OIL 8

05I - Other Hair Preparations MACADAMIA TERNIFOLIA SEED OIL 7

06H - Other Hair Coloring Preparation MACADAMIA TERNIFOLIA SEED OIL 3

07B - Face Powders MACADAMIA TERNIFOLIA SEED OIL 1

07C - Foundations MACADAMIA TERNIFOLIA SEED OIL 3

07D - Leg and Body Paints MACADAMIA TERNIFOLIA SEED OIL 1

07E - Lipstick MACADAMIA TERNIFOLIA SEED OIL 33

07F - Makeup Bases MACADAMIA TERNIFOLIA SEED OIL 1

07G - Rouges MACADAMIA TERNIFOLIA SEED OIL 4

07I - Other Makeup Preparations MACADAMIA TERNIFOLIA SEED OIL 7

08F - Nail Polish and Enamel Removers MACADAMIA TERNIFOLIA SEED OIL 1

10A - Bath Soaps and Detergents MACADAMIA TERNIFOLIA SEED OIL 6

10E - Other Personal Cleanliness Products MACADAMIA TERNIFOLIA SEED OIL 6

11E - Shaving Cream MACADAMIA TERNIFOLIA SEED OIL 1

11G - Other Shaving Preparation Products MACADAMIA TERNIFOLIA SEED OIL 1

12A - Cleansing MACADAMIA TERNIFOLIA SEED OIL 17

12C - Face and Neck (exc shave) MACADAMIA TERNIFOLIA SEED OIL 32

12D - Body and Hand (exc shave) MACADAMIA TERNIFOLIA SEED OIL 90

12E - Foot Powders and Sprays MACADAMIA TERNIFOLIA SEED OIL 2

12F - Moisturizing MACADAMIA TERNIFOLIA SEED OIL 195

12G - Night MACADAMIA TERNIFOLIA SEED OIL 17

12H - Paste Masks (mud packs) MACADAMIA TERNIFOLIA SEED OIL 6

12I - Skin Fresheners MACADAMIA TERNIFOLIA SEED OIL 1

12J - Other Skin Care Preps MACADAMIA TERNIFOLIA SEED OIL 41

13A - Suntan Gels, Creams, and Liquids MACADAMIA TERNIFOLIA SEED OIL 1

13C - Other Suntan Preparations MACADAMIA TERNIFOLIA SEED OIL 3

05A - Hair Conditioner SCHINZIOPHYTON RAUTANENII KERNEL OIL 1

05F - Shampoos (non-coloring) SCHINZIOPHYTON RAUTANENII KERNEL OIL 1

05I - Other Hair Preparations SCHINZIOPHYTON RAUTANENII KERNEL OIL 1

12D - Body and Hand (exc shave) SCHINZIOPHYTON RAUTANENII KERNEL OIL 1

12F - Moisturizing SCHINZIOPHYTON RAUTANENII KERNEL OIL 1

12J - Other Skin Care Preps SCHINZIOPHYTON RAUTANENII KERNEL OIL 1

03G - Other Eye Makeup Preparations CARYA ILLINOENSIS (PECAN) SEED OIL 1

10E - Other Personal Cleanliness Products CARYA ILLINOENSIS (PECAN) SEED OIL 1

12C - Face and Neck (exc shave) CARYA ILLINOENSIS (PECAN) SEED OIL 1

12D - Body and Hand (exc shave) CARYA ILLINOENSIS (PECAN) SEED OIL 2

12F - Moisturizing CARYA ILLINOENSIS (PECAN) SEED OIL 1

12G - Night CARYA ILLINOENSIS (PECAN) SEED OIL 2

01A - Baby Shampoos PISTACIA VERA SEED OIL 2

01C - Other Baby Products PISTACIA VERA SEED OIL 1

02A - Bath Oils, Tablets, and Salts PISTACIA VERA SEED OIL 3

02B - Bubble Baths PISTACIA VERA SEED OIL 4

02D - Other Bath Preparations PISTACIA VERA SEED OIL 1

03B - Eyeliner PISTACIA VERA SEED OIL 2

03C - Eye Shadow PISTACIA VERA SEED OIL 1

03E - Eye Makeup Remover PISTACIA VERA SEED OIL 1

03F - Mascara PISTACIA VERA SEED OIL 1

03G - Other Eye Makeup Preparations PISTACIA VERA SEED OIL 2

05A - Hair Conditioner PISTACIA VERA SEED OIL 3

05F - Shampoos (non-coloring) PISTACIA VERA SEED OIL 7

05G - Tonics, Dressings, and Other Hair Grooming Aids PISTACIA VERA SEED OIL 4

05I - Other Hair Preparations PISTACIA VERA SEED OIL 2

07A - Blushers (all types) PISTACIA VERA SEED OIL 1

07B - Face Powders PISTACIA VERA SEED OIL 1

07E - Lipstick PISTACIA VERA SEED OIL 2

07F - Makeup Bases PISTACIA VERA SEED OIL 1

07I - Other Makeup Preparations PISTACIA VERA SEED OIL 2

08E - Nail Polish and Enamel PISTACIA VERA SEED OIL 1

08G - Other Manicuring Preparations PISTACIA VERA SEED OIL 1



09A - Dentifrices PISTACIA VERA SEED OIL 2

09B - Mouthwashes and Breath Fresheners PISTACIA VERA SEED OIL 2

10A - Bath Soaps and Detergents PISTACIA VERA SEED OIL 13

10E - Other Personal Cleanliness Products PISTACIA VERA SEED OIL 2

11A - Aftershave Lotion PISTACIA VERA SEED OIL 1

11F - Shaving Soap PISTACIA VERA SEED OIL 1

12A - Cleansing PISTACIA VERA SEED OIL 5

12C - Face and Neck (exc shave) PISTACIA VERA SEED OIL 28

12D - Body and Hand (exc shave) PISTACIA VERA SEED OIL 14

12F - Moisturizing PISTACIA VERA SEED OIL 28

12G - Night PISTACIA VERA SEED OIL 1

12H - Paste Masks (mud packs) PISTACIA VERA SEED OIL 5

12I - Skin Fresheners PISTACIA VERA SEED OIL 6

12J - Other Skin Care Preps PISTACIA VERA SEED OIL 7

03G - Other Eye Makeup Preparations PLUKENETIA VOLUBILIS SEED OIL 1

07E - Lipstick PLUKENETIA VOLUBILIS SEED OIL 3

12C - Face and Neck (exc shave) PLUKENETIA VOLUBILIS SEED OIL 4

12F - Moisturizing PLUKENETIA VOLUBILIS SEED OIL 2

12G - Night PLUKENETIA VOLUBILIS SEED OIL 2

12H - Paste Masks (mud packs) PLUKENETIA VOLUBILIS SEED OIL 1

02D - Other Bath Preparations JUGLANS REGIA (WALNUT) SEED OIL 2

03D - Eye Lotion JUGLANS REGIA (WALNUT) SEED OIL 1

05A - Hair Conditioner JUGLANS REGIA (WALNUT) SEED OIL 1

12C - Face and Neck (exc shave) JUGLANS REGIA (WALNUT) SEED OIL 2

12D - Body and Hand (exc shave) JUGLANS REGIA (WALNUT) SEED OIL 7

12F - Moisturizing JUGLANS REGIA (WALNUT) SEED OIL 1

12J - Other Skin Care Preps JUGLANS REGIA (WALNUT) SEED OIL 1



01C - Other Baby Products COCONUT ACID 1

03B - Eyeliner COCONUT ACID 1

05F - Shampoos (non-coloring) COCONUT ACID 1

07B - Face Powders COCONUT ACID 2

07C - Foundations COCONUT ACID 8

10A - Bath Soaps and Detergents COCONUT ACID 99

10E - Other Personal Cleanliness Products COCONUT ACID 2

11A - Aftershave Lotion COCONUT ACID 1

11E - Shaving Cream COCONUT ACID 15

11F - Shaving Soap COCONUT ACID 1

12A - Cleansing COCONUT ACID 5

12C - Face and Neck (exc shave) COCONUT ACID 1

12D - Body and Hand (exc shave) COCONUT ACID 1

12F - Moisturizing COCONUT ACID 1

12H - Paste Masks (mud packs) COCONUT ACID 1

12J - Other Skin Care Preps COCONUT ACID 1

01B - Baby Lotions, Oils, Powders, and Creams COCOS NUCIFERA (COCONUT) OIL 8

01C - Other Baby Products COCOS NUCIFERA (COCONUT) OIL 7

02A - Bath Oils, Tablets, and Salts COCOS NUCIFERA (COCONUT) OIL 3

02B - Bubble Baths COCOS NUCIFERA (COCONUT) OIL 1

02D - Other Bath Preparations COCOS NUCIFERA (COCONUT) OIL 11

03B - Eyeliner COCOS NUCIFERA (COCONUT) OIL 7

03C - Eye Shadow COCOS NUCIFERA (COCONUT) OIL 3

03D - Eye Lotion COCOS NUCIFERA (COCONUT) OIL 4

03E - Eye Makeup Remover COCOS NUCIFERA (COCONUT) OIL 3

03G - Other Eye Makeup Preparations COCOS NUCIFERA (COCONUT) OIL 8

04A - Cologne and Toilet waters COCOS NUCIFERA (COCONUT) OIL 3

04C - Powders (dusting and talcum, excluding aftershave talc) COCOS NUCIFERA (COCONUT) OIL 1

04E - Other Fragrance Preparation COCOS NUCIFERA (COCONUT) OIL 5

05A - Hair Conditioner COCOS NUCIFERA (COCONUT) OIL 50

05C - Hair Straighteners COCOS NUCIFERA (COCONUT) OIL 21

05F - Shampoos (non-coloring) COCOS NUCIFERA (COCONUT) OIL 28

05G - Tonics, Dressings, and Other Hair Grooming Aids COCOS NUCIFERA (COCONUT) OIL 40

05I - Other Hair Preparations COCOS NUCIFERA (COCONUT) OIL 37

06A - Hair Dyes and Colors (all types requiring caution statements and patch tests)COCOS NUCIFERA (COCONUT) OIL 65

06B - Hair Tints COCOS NUCIFERA (COCONUT) OIL 1

06G - Hair Bleaches COCOS NUCIFERA (COCONUT) OIL 3

07A - Blushers (all types) COCOS NUCIFERA (COCONUT) OIL 3

07B - Face Powders COCOS NUCIFERA (COCONUT) OIL 3

07C - Foundations COCOS NUCIFERA (COCONUT) OIL 4

07D - Leg and Body Paints COCOS NUCIFERA (COCONUT) OIL 1

07E - Lipstick COCOS NUCIFERA (COCONUT) OIL 44

07I - Other Makeup Preparations COCOS NUCIFERA (COCONUT) OIL 12

08B - Cuticle Softeners COCOS NUCIFERA (COCONUT) OIL 2

08G - Other Manicuring Preparations COCOS NUCIFERA (COCONUT) OIL 3

10A - Bath Soaps and Detergents COCOS NUCIFERA (COCONUT) OIL 147

10E - Other Personal Cleanliness Products COCOS NUCIFERA (COCONUT) OIL 14

11E - Shaving Cream COCOS NUCIFERA (COCONUT) OIL 6

11G - Other Shaving Preparation Products COCOS NUCIFERA (COCONUT) OIL 9

12A - Cleansing COCOS NUCIFERA (COCONUT) OIL 20

12B - Depilatories COCOS NUCIFERA (COCONUT) OIL 4

12C - Face and Neck (exc shave) COCOS NUCIFERA (COCONUT) OIL 13

12D - Body and Hand (exc shave) COCOS NUCIFERA (COCONUT) OIL 65

12E - Foot Powders and Sprays COCOS NUCIFERA (COCONUT) OIL 1

12F - Moisturizing COCOS NUCIFERA (COCONUT) OIL 82

12G - Night COCOS NUCIFERA (COCONUT) OIL 3

12H - Paste Masks (mud packs) COCOS NUCIFERA (COCONUT) OIL 3

12I - Skin Fresheners COCOS NUCIFERA (COCONUT) OIL 3

12J - Other Skin Care Preps COCOS NUCIFERA (COCONUT) OIL 24

13A - Suntan Gels, Creams, and Liquids COCOS NUCIFERA (COCONUT) OIL 13

13B - Indoor Tanning Preparations COCOS NUCIFERA (COCONUT) OIL 8

13C - Other Suntan Preparations COCOS NUCIFERA (COCONUT) OIL 2

01C - Other Baby Products HYDROGENATED COCONUT OIL 1

03A - Eyebrow Pencil HYDROGENATED COCONUT OIL 2

03B - Eyeliner HYDROGENATED COCONUT OIL 3

03C - Eye Shadow HYDROGENATED COCONUT OIL 1

03G - Other Eye Makeup Preparations HYDROGENATED COCONUT OIL 1

05A - Hair Conditioner HYDROGENATED COCONUT OIL 2

05G - Tonics, Dressings, and Other Hair Grooming Aids HYDROGENATED COCONUT OIL 1

07B - Face Powders HYDROGENATED COCONUT OIL 3

07C - Foundations HYDROGENATED COCONUT OIL 4



07E - Lipstick HYDROGENATED COCONUT OIL 10

07I - Other Makeup Preparations HYDROGENATED COCONUT OIL 4

10A - Bath Soaps and Detergents HYDROGENATED COCONUT OIL 16

10E - Other Personal Cleanliness Products HYDROGENATED COCONUT OIL 2

11E - Shaving Cream HYDROGENATED COCONUT OIL 1

11F - Shaving Soap HYDROGENATED COCONUT OIL 1

12A - Cleansing HYDROGENATED COCONUT OIL 3

12C - Face and Neck (exc shave) HYDROGENATED COCONUT OIL 10

12D - Body and Hand (exc shave) HYDROGENATED COCONUT OIL 7

12F - Moisturizing HYDROGENATED COCONUT OIL 21

12H - Paste Masks (mud packs) HYDROGENATED COCONUT OIL 1

12J - Other Skin Care Preps HYDROGENATED COCONUT OIL 9

13B - Indoor Tanning Preparations HYDROGENATED COCONUT OIL 2

10A - Bath Soaps and Detergents MAGNESIUM COCOATE 9

05F - Shampoos (non-coloring) POTASSIUM COCOATE 2

10A - Bath Soaps and Detergents POTASSIUM COCOATE 18

10E - Other Personal Cleanliness Products POTASSIUM COCOATE 8

11E - Shaving Cream POTASSIUM COCOATE 3

11F - Shaving Soap POTASSIUM COCOATE 1

12A - Cleansing POTASSIUM COCOATE 8

01C - Other Baby Products SODIUM COCOATE 5

02B - Bubble Baths SODIUM COCOATE 3

05A - Hair Conditioner SODIUM COCOATE 1

05F - Shampoos (non-coloring) SODIUM COCOATE 65

05G - Tonics, Dressings, and Other Hair Grooming Aids SODIUM COCOATE 1

05I - Other Hair Preparations SODIUM COCOATE 4

10A - Bath Soaps and Detergents SODIUM COCOATE 226

10E - Other Personal Cleanliness Products SODIUM COCOATE 12

11A - Aftershave Lotion SODIUM COCOATE 1

11E - Shaving Cream SODIUM COCOATE 2

11F - Shaving Soap SODIUM COCOATE 2

12A - Cleansing SODIUM COCOATE 12

12H - Paste Masks (mud packs) SODIUM COCOATE 1

12J - Other Skin Care Preps SODIUM COCOATE 5

03D - Eye Lotion ARACHIS HYPOGAEA (PEANUT) OIL 1

03G - Other Eye Makeup Preparations ARACHIS HYPOGAEA (PEANUT) OIL 3

05A - Hair Conditioner ARACHIS HYPOGAEA (PEANUT) OIL 8

05G - Tonics, Dressings, and Other Hair Grooming Aids ARACHIS HYPOGAEA (PEANUT) OIL 7

05I - Other Hair Preparations ARACHIS HYPOGAEA (PEANUT) OIL 6

07I - Other Makeup Preparations ARACHIS HYPOGAEA (PEANUT) OIL 1

10A - Bath Soaps and Detergents ARACHIS HYPOGAEA (PEANUT) OIL 2

12A - Cleansing ARACHIS HYPOGAEA (PEANUT) OIL 5

12C - Face and Neck (exc shave) ARACHIS HYPOGAEA (PEANUT) OIL 16

12D - Body and Hand (exc shave) ARACHIS HYPOGAEA (PEANUT) OIL 6

12E - Foot Powders and Sprays ARACHIS HYPOGAEA (PEANUT) OIL 2

12F - Moisturizing ARACHIS HYPOGAEA (PEANUT) OIL 7

12G - Night ARACHIS HYPOGAEA (PEANUT) OIL 3

12J - Other Skin Care Preps ARACHIS HYPOGAEA (PEANUT) OIL 5

13A - Suntan Gels, Creams, and Liquids ARACHIS HYPOGAEA (PEANUT) OIL 1

13B - Indoor Tanning Preparations ARACHIS HYPOGAEA (PEANUT) OIL 1

12C - Face and Neck (exc shave) HYDROGENATED PEANUT OIL 3

12D - Body and Hand (exc shave) HYDROGENATED PEANUT OIL 5

12G - Night HYDROGENATED PEANUT OIL 3

12J - Other Skin Care Preps HYDROGENATED PEANUT OIL 1

01B - Baby Lotions, Oils, Powders, and Creams BUTYROSPERMUM PARKII (SHEA BUTTER) 19

01C - Other Baby Products BUTYROSPERMUM PARKII (SHEA BUTTER) 5

02A - Bath Oils, Tablets, and Salts BUTYROSPERMUM PARKII (SHEA BUTTER) 9

02B - Bubble Baths BUTYROSPERMUM PARKII (SHEA BUTTER) 1

02D - Other Bath Preparations BUTYROSPERMUM PARKII (SHEA BUTTER) 3

03A - Eyebrow Pencil BUTYROSPERMUM PARKII (SHEA BUTTER) 3

03B - Eyeliner BUTYROSPERMUM PARKII (SHEA BUTTER) 9

03C - Eye Shadow BUTYROSPERMUM PARKII (SHEA BUTTER) 10

03D - Eye Lotion BUTYROSPERMUM PARKII (SHEA BUTTER) 52

03E - Eye Makeup Remover BUTYROSPERMUM PARKII (SHEA BUTTER) 1

03F - Mascara BUTYROSPERMUM PARKII (SHEA BUTTER) 5

03G - Other Eye Makeup Preparations BUTYROSPERMUM PARKII (SHEA BUTTER) 28

04E - Other Fragrance Preparation BUTYROSPERMUM PARKII (SHEA BUTTER) 7



05A - Hair Conditioner BUTYROSPERMUM PARKII (SHEA BUTTER) 64

05B - Hair Spray (aerosol fixatives) BUTYROSPERMUM PARKII (SHEA BUTTER) 2

05C - Hair Straighteners BUTYROSPERMUM PARKII (SHEA BUTTER) 23

05E - Rinses (non-coloring) BUTYROSPERMUM PARKII (SHEA BUTTER) 2

05F - Shampoos (non-coloring) BUTYROSPERMUM PARKII (SHEA BUTTER) 32

05G - Tonics, Dressings, and Other Hair Grooming Aids BUTYROSPERMUM PARKII (SHEA BUTTER) 50

05I - Other Hair Preparations BUTYROSPERMUM PARKII (SHEA BUTTER) 37

06D - Hair Shampoos (coloring) BUTYROSPERMUM PARKII (SHEA BUTTER) 1

06H - Other Hair Coloring Preparation BUTYROSPERMUM PARKII (SHEA BUTTER) 3

07A - Blushers (all types) BUTYROSPERMUM PARKII (SHEA BUTTER) 9

07B - Face Powders BUTYROSPERMUM PARKII (SHEA BUTTER) 1

07C - Foundations BUTYROSPERMUM PARKII (SHEA BUTTER) 15

07E - Lipstick BUTYROSPERMUM PARKII (SHEA BUTTER) 128

07F - Makeup Bases BUTYROSPERMUM PARKII (SHEA BUTTER) 4

07G - Rouges BUTYROSPERMUM PARKII (SHEA BUTTER) 1

07I - Other Makeup Preparations BUTYROSPERMUM PARKII (SHEA BUTTER) 41

08B - Cuticle Softeners BUTYROSPERMUM PARKII (SHEA BUTTER) 4

08C - Nail Creams and Lotions BUTYROSPERMUM PARKII (SHEA BUTTER) 2

08G - Other Manicuring Preparations BUTYROSPERMUM PARKII (SHEA BUTTER) 1

10A - Bath Soaps and Detergents BUTYROSPERMUM PARKII (SHEA BUTTER) 59

10B - Deodorants (underarm) BUTYROSPERMUM PARKII (SHEA BUTTER) 2

10E - Other Personal Cleanliness Products BUTYROSPERMUM PARKII (SHEA BUTTER) 42

11A - Aftershave Lotion BUTYROSPERMUM PARKII (SHEA BUTTER) 17

11B - Beard Softeners BUTYROSPERMUM PARKII (SHEA BUTTER) 1

11E - Shaving Cream BUTYROSPERMUM PARKII (SHEA BUTTER) 7

11G - Other Shaving Preparation Products BUTYROSPERMUM PARKII (SHEA BUTTER) 2

12A - Cleansing BUTYROSPERMUM PARKII (SHEA BUTTER) 45

12B - Depilatories BUTYROSPERMUM PARKII (SHEA BUTTER) 2

12C - Face and Neck (exc shave) BUTYROSPERMUM PARKII (SHEA BUTTER) 153

12D - Body and Hand (exc shave) BUTYROSPERMUM PARKII (SHEA BUTTER) 269

12E - Foot Powders and Sprays BUTYROSPERMUM PARKII (SHEA BUTTER) 8

12F - Moisturizing BUTYROSPERMUM PARKII (SHEA BUTTER) 516

12G - Night BUTYROSPERMUM PARKII (SHEA BUTTER) 84

12H - Paste Masks (mud packs) BUTYROSPERMUM PARKII (SHEA BUTTER) 21

12I - Skin Fresheners BUTYROSPERMUM PARKII (SHEA BUTTER) 4

12J - Other Skin Care Preps BUTYROSPERMUM PARKII (SHEA BUTTER) 107

13A - Suntan Gels, Creams, and Liquids BUTYROSPERMUM PARKII (SHEA BUTTER) 11

13B - Indoor Tanning Preparations BUTYROSPERMUM PARKII (SHEA BUTTER) 21

13C - Other Suntan Preparations BUTYROSPERMUM PARKII (SHEA BUTTER) 7

02A - Bath Oils, Tablets, and Salts BUTYROSPERMUM PARKII (SHEA BUTTER) OIL 1

02B - Bubble Baths BUTYROSPERMUM PARKII (SHEA BUTTER) OIL 2

03D - Eye Lotion BUTYROSPERMUM PARKII (SHEA BUTTER) OIL 1

10A - Bath Soaps and Detergents BUTYROSPERMUM PARKII (SHEA BUTTER) OIL 3

12F - Moisturizing BUTYROSPERMUM PARKII (SHEA BUTTER) OIL 12

12G - Night BUTYROSPERMUM PARKII (SHEA BUTTER) OIL 2

12J - Other Skin Care Preps BUTYROSPERMUM PARKII (SHEA BUTTER) OIL 1

01B - Baby Lotions, Oils, Powders, and Creams BUTYROSPERMUM PARKII (SHEA BUTTER) UNSAPONIFIABLES 1

03B - Eyeliner BUTYROSPERMUM PARKII (SHEA BUTTER) UNSAPONIFIABLES 3

03C - Eye Shadow BUTYROSPERMUM PARKII (SHEA BUTTER) UNSAPONIFIABLES 4

05A - Hair Conditioner BUTYROSPERMUM PARKII (SHEA BUTTER) UNSAPONIFIABLES 1

05F - Shampoos (non-coloring) BUTYROSPERMUM PARKII (SHEA BUTTER) UNSAPONIFIABLES 2

05I - Other Hair Preparations BUTYROSPERMUM PARKII (SHEA BUTTER) UNSAPONIFIABLES 2

07A - Blushers (all types) BUTYROSPERMUM PARKII (SHEA BUTTER) UNSAPONIFIABLES 3

07B - Face Powders BUTYROSPERMUM PARKII (SHEA BUTTER) UNSAPONIFIABLES 4

07C - Foundations BUTYROSPERMUM PARKII (SHEA BUTTER) UNSAPONIFIABLES 1

07E - Lipstick BUTYROSPERMUM PARKII (SHEA BUTTER) UNSAPONIFIABLES 2

12C - Face and Neck (exc shave) BUTYROSPERMUM PARKII (SHEA BUTTER) UNSAPONIFIABLES 5

12D - Body and Hand (exc shave) BUTYROSPERMUM PARKII (SHEA BUTTER) UNSAPONIFIABLES 1

12F - Moisturizing BUTYROSPERMUM PARKII (SHEA BUTTER) UNSAPONIFIABLES 8

12J - Other Skin Care Preps BUTYROSPERMUM PARKII (SHEA BUTTER) UNSAPONIFIABLES 1



10A - Bath Soaps and Detergents HYDROGENATED SHEA BUTTER 2

12F - Moisturizing HYDROGENATED SHEA BUTTER 2

02A - Bath Oils, Tablets, and Salts ALEURITES MOLUCCANA SEED OIL 5

02B - Bubble Baths ALEURITES MOLUCCANA SEED OIL 1

03D - Eye Lotion ALEURITES MOLUCCANA SEED OIL 2

03F - Mascara ALEURITES MOLUCCANA SEED OIL 3

03G - Other Eye Makeup Preparations ALEURITES MOLUCCANA SEED OIL 1

04E - Other Fragrance Preparation ALEURITES MOLUCCANA SEED OIL 8

05A - Hair Conditioner ALEURITES MOLUCCANA SEED OIL 15

05B - Hair Spray (aerosol fixatives) ALEURITES MOLUCCANA SEED OIL 7

05E - Rinses (non-coloring) ALEURITES MOLUCCANA SEED OIL 1

05F - Shampoos (non-coloring) ALEURITES MOLUCCANA SEED OIL 15

05G - Tonics, Dressings, and Other Hair Grooming Aids ALEURITES MOLUCCANA SEED OIL 12

05H - Wave Sets ALEURITES MOLUCCANA SEED OIL 1

05I - Other Hair Preparations ALEURITES MOLUCCANA SEED OIL 7

07E - Lipstick ALEURITES MOLUCCANA SEED OIL 1

08B - Cuticle Softeners ALEURITES MOLUCCANA SEED OIL 1

08C - Nail Creams and Lotions ALEURITES MOLUCCANA SEED OIL 2

08G - Other Manicuring Preparations ALEURITES MOLUCCANA SEED OIL 1

10A - Bath Soaps and Detergents ALEURITES MOLUCCANA SEED OIL 2

10E - Other Personal Cleanliness Products ALEURITES MOLUCCANA SEED OIL 3

11E - Shaving Cream ALEURITES MOLUCCANA SEED OIL 1

12A - Cleansing ALEURITES MOLUCCANA SEED OIL 3

12C - Face and Neck (exc shave) ALEURITES MOLUCCANA SEED OIL 2

12D - Body and Hand (exc shave) ALEURITES MOLUCCANA SEED OIL 14

12F - Moisturizing ALEURITES MOLUCCANA SEED OIL 23

12G - Night ALEURITES MOLUCCANA SEED OIL 1

12J - Other Skin Care Preps ALEURITES MOLUCCANA SEED OIL 5

13A - Suntan Gels, Creams, and Liquids ALEURITES MOLUCCANA SEED OIL 1

13B - Indoor Tanning Preparations ALEURITES MOLUCCANA SEED OIL 1

13C - Other Suntan Preparations ALEURITES MOLUCCANA SEED OIL 2

02B - Bubble Baths BERTHOLLETIA EXCELSA SEED OIL 3

03D - Eye Lotion BERTHOLLETIA EXCELSA SEED OIL 1

05A - Hair Conditioner BERTHOLLETIA EXCELSA SEED OIL 5

05F - Shampoos (non-coloring) BERTHOLLETIA EXCELSA SEED OIL 5

05I - Other Hair Preparations BERTHOLLETIA EXCELSA SEED OIL 2

06A - Hair Dyes and Colors (all types requiring caution statements and patch tests)BERTHOLLETIA EXCELSA SEED OIL 14

07C - Foundations BERTHOLLETIA EXCELSA SEED OIL 1

10A - Bath Soaps and Detergents BERTHOLLETIA EXCELSA SEED OIL 3

10E - Other Personal Cleanliness Products BERTHOLLETIA EXCELSA SEED OIL 4

12C - Face and Neck (exc shave) BERTHOLLETIA EXCELSA SEED OIL 2

12D - Body and Hand (exc shave) BERTHOLLETIA EXCELSA SEED OIL 1

12E - Foot Powders and Sprays BERTHOLLETIA EXCELSA SEED OIL 1

12F - Moisturizing BERTHOLLETIA EXCELSA SEED OIL 11

12H - Paste Masks (mud packs) BERTHOLLETIA EXCELSA SEED OIL 1

12J - Other Skin Care Preps BERTHOLLETIA EXCELSA SEED OIL 1

12C - Face and Neck (exc shave) GEVUINA AVELLANA OIL 2

12D - Body and Hand (exc shave) GEVUINA AVELLANA OIL 2

12F - Moisturizing GEVUINA AVELLANA OIL 1


DATE:

Products CouncilCommitted to Safety,Quality & Innovation

John Bailey, Ph.15EZ\3_i_.._O___.. £[i toIndustry Liaison to the CIR Expert Panel

June 29, 2010

SUBJECT: HRIPT of a Lipstick Containing Plukenetia Volubilis Seed Oil

Consumer Product Testing Co. 2008. Repeated insult patch test of a lipstick containing 0.509847%Plukenetia Volubilis Seed Oil. Experiment Reference Number C08-5394.06.

1101 17th Street, N.W., Suite 30O Washington, D.C. 20036-4702 202.331.1770 202.331.1969 (fax) www.personalcarecouncil.org

Personal Carei

Memorandum

TO: F. Alan Andersen, Ph.D.Director - COSMETIC INGREDIENT REVIEW (Cifi)

FROM:


Personal Care Products CounciCommitted to Safety,Quality & Innovation

Memorandum

TO:

FROM:

DATE:

SUBJECT:

F. Alan Andersen, Ph.D.Director - COSMETIC INGREDIENT REVIEW (CW)

John Bailey,Industry Liaison to the CIR Expert Panel

July 19, 2010

Composition and specifications of 6 nut oils

John L Seaton & Co Ltd. 2005. Seatons Arachis Oil Data sheet.

John L Seaton & Co Ltd.











2010.

2005.

2009.

2005.

2010.

2005.

2010.

2006.

2006.

2005.

2009.

1101 17th Street, N.W., Suite 300 Washington, D.C. 20036-4702 202.331.1770 202.331.1969 (fax) www.personalcarecouncil.org

Arachis Oil BP/EP Specification.

Seatons Shea Nut Butter Data sheet.

Seatons Refined Shea Nut Butter Specification.

Seatons Hazelnut Oil Data sheet.

Seatons Refined Hazelnut Oil Specification.

Seatons Macadamia Oil Data sheet.

Seatons Refined Macadamia Oil Specification.

Seatons Kukui Nut Oil Data sheet.

Seatons Refined Kukui Nut Oil Specification.

Seatons Sweet Almond Oil Data sheet.

Seatons Refined Sweet Almond Oil Cosmetic Blend Specification.


OriginAlso know as peanut oil and groundnut oil, arachis oil is obtained from the seed kernels ofArachis hypogaea (L) which is grown in some parts of Europe, Africa, India and China. Itis refined to give pale yellow oil with a slight odour and mild taste.

Characteristics and applicationsArachis oil has traditionally been used in sunscreens and after sun formulations. It canalso be used in products to treat dry skin conditions.

• R & D arachis oil to meet BP, EP and USP specs• Organic arachis oil

Typical propertiesFree fatty acidsIodine valueSaponification valueRelative density @ 20°CRefractive index @ 40°CColour, Lovibond 5.25” cellRequired HLB value

0.5 max80- 106185 - 1950.9 12 - 0.9201.462 - 1.46420 yellow, 2.5 red max6

Typical fatty acid profilePalmitic C16Stearic C18Oleic C18:1Linoleic C18:2Linolenic C18:3

7- 16%1 - 6%35 - 72%13 - 43%0.6% max

Registration informationINCI nameCAS numberEINECS number

Arachis Hypogaea Oil8002-03-7232-296-4

Specifications, starting formulations and MSDS are available on request.

Non-warrantyInformation in this leaflet is given in good faith. John L Seaton & Co Ltd and its associate companies cannot assumeany liability expressed or implied in the presentation of this data, nor should information contained herein be construedas granting licence to practise any methods or compositions of matter covered by British or other patents. Details arecorrect at the date of issue (April 2005).

John L Seaton & Co LtdFirst Floor 7 Waterside Business Park Livingstone RoadHessle East Yorkshire HU13 OEG United KingdomTel + 44 (0)1482 579700 Fax + 44 (0)1482 647313Website www.croda.com/seatonsEmail [email protected]

Seatons Arachis Oil

Range available


Specification

Acid value - 0.5

Peroxide value - 5.0

Unsaponifiable matter - 1.0% w/w

Alkaline impurities Complies with the test for alkalineimpurities in fatty oils

Moisture content (if intended for the - 0.3%use in parenteral forms)

Fatty acid composition Mm Max

Saturated fatty acids of - 0.4%

chain length less than C16

C16:0 Palmitic acid 7.0% 16.0%

C18:0 Stearic acid 1.3% 6.5%

C18:1 Oleic acid 35.0% 72.0%

C18:2 Linoleic acid 13.0% 43.0%

C18:3 Linolenic acid - 0.6%

C20:0 Arachidic acid 0.5% 3.0%

C20:1 Eicosenoic acid 0.5% 2.1%

C22:0 Behenic acid 1.0% 5.0%

C22:1 Erucic acid - 0.5%

C24:0 Lignoceric acid 0.5% 3.0%

Supplied under a quality management system registered to ISO 9001

Non-warrantyThe information in this publication is believed to be accurate and is given in good faith but no representation or warranty as to its completeness or accuracy is made.Suggestions for uses or applications are only opinions. Users are responsible for determining the suitability of these products for their own particular purpose.No representation or warranty, express or implied, is made with respect to information or products including without limitation warranties of merchantability or fitnessfor a particular purpose or non-infnngement of any third party patent or other intellectual property rights induding without limit copyright, trademark and designs.Any trademarks identified herein are trademarks 0f the Croda group of companies.

John L Seaton & Co LimitedFirst Floor 7 Waterside Business Park Livingstone RoadHessle East Yorkshire HU 13 OEG EnglandTel +44 (0)1482 579700 Fax +44(0)1482 647313Website www.seatons-uk.co.ukEmail enquirieaaeatons-uk.co.uk

Product Arachis Oil BP/EP

Definition Arachis oil is the fixed oil obtained from the shelled seeds of Arachis hypogaea(L) and further refined. It conforms to the monograph contained in the BritishPharmacopoeia 2010 and European Pharmacopoeia 6.0.

Characteristics

JLS specification number

Test

A clear, yellowish, viscous oil.Very slightly soluble in alcohol, miscible with light petroleumRelative density about 0.915. It solidifes at about 2°C.

P9046

Range MethodMm Max

Methods as described in the

British Pharmacopoeia

Date of issueConfirmed

Storage conditions Arachis oil should be kept in a well filled, well closed container and protectedfrom light.

Issued by PA Bentley

August2009January 2010


Seatons Shea Nut Butter

OriginShea nut butter is a rich buttery oil produced by cold pressing the fruits of the shea tree(Butyrospermum parkii), which is grown in central Africa. Shea trees are hard todomesticate and only start bearing fruit after 15/20 years. Each tree bears on average 15-20 kg of fruit which yield just 1 .5kg of butter. Shea nut buffer is also known as Karite butterand is a creamy white/off white solid at room temperature.

Characteristics and applicationsShea nut butter has skin soothing and replenishing properties so is mainly used inproducts for the protection of dry and cracked skin. It can also be used in soaps as it hasa relatively high melting point.

Range available

• Refined shea nut buffer• Organic shea nut buffer

Typical propertiesAcid value 1.5 maxIodine value 45-73Saponification value 165-190Colour, Lovibond 5.25” cell 20 yellow, 3 red maxSlip melting point 28 - 42CCRequired HLB value 8

Typical fatty acid profilePalmitic C16 3-9%Stearic C18 34-48%Oleic C18:1 38-50%Linoleic C18:2 3-8%Linolenic C18:3 0.5% max

Monounsaturated fatty acids 45%Saturated fatty acids 47%Polyunsaturated fatty acids 6%Trans fatty acids 0

Registration informationINCI name Butyrospermum Parkii ButterCAS number 68956-68-3EINECS number 273-313-5

Specification and MSDS available on request.

Non-warrantyInformation in this leaflet is given in good faith. John L Seaton & Co Ltd and its associate companies cannot assumeany liability expressed or implied in the presentation of this data, nor should information contained herein be construedas granting licence to practise any methods or compositions of matter covered by British or other patents. Details arecorrect at the date of issue (April 2005),

John L Seaton & Co LtdFirst Floor 7 Waterside Business Park Livingstone RoadHessle East Yorkshire HU13 OEG United KingdomTel + 44 (0)1482 579700 Fax + 44(0)1482647313Website www.croda.com/seatonsEmail [email protected]


Specification

Product Seatons Refined Shea Nut Butter

Description Speciality vegetable oil obtained from the kernels of the Shea tree(Butyrospermum parkii)

JLS specification number P9010

Test Range Method

Mm Max

Physical Properties

Appearance Off white / yellow solid Visual

Chemical Properties

Free fatty Acid content (% as oleic) - 1.0 BS 684: Section 2.10

Iodine Value (gI2JlOOg oil) 45 73 BS 684: Section 2.13

Peroxide value (meqO2lkg) - 5.0 BS 684: Section 2.14

Fatty Acid Profile (main acids) GLC

C16:0 Palmitic acid 2.0 8.0%

Cl 8:0 Stearic acid 36.0 50.0%

C18:1 Oleic acid 40.0 50.0%

C18:2 Linoleic acid 4.0 8.0%

C20:0 Arachidic acid - 3.0%

Issued by: P.A.Bentley

Date of issue: December 2009

Supplied under a quality management system registered to Iso 9001

Non-warrantyThe information in this publication is believed to be accurate and is given in good faith but no representation or warranty as to its completeness or accuracy is made.Suggestions for uses or applications are only opinions. Users are responsible for determining the suitability of these products for their own particular purpose.No representahon or warranty. eopress or implied, is made with rasped to information or products including without limitation warranties of merchantability or fitnessfor a particular purpose or non-infringement of any third party patentor other intellectual property rights including without limit copyright, trademark and designs.My trademarks identified herein are trademarks of the Croda group of companies.

John L Seaton & Co limitedFirst Floor 7 Waterside Susiness Park Livingstone Road

Hessle East Yorkshire HU 13 OEG EnglandTel +44 (0)1482 579700 Fax +44 (0)1482 647313Website www.seatons-uk.co.ukEmail [email protected]


Seatons Hazelnut Oil

OriginHazelnut oil is produced from the nut kernels of the hazelnut shrub, grown in West Africa.The oil is extracted by mechanical pressing followed by filtration and the oil can be furtherrefined.

Characteristics and applicationsHazelnut is rich in vitamins and is easily absorbed into skin where it nourishes andrevitalises all skin types. Hazelnut oil is said to tone and tighten the skin and helpsmaintain firmness and elasticity. It spreads onto skin easily, is lubricating, and therefore isa very good base oil for massage. It also makes a good bath oil.

Range available

• Cold pressed hazelnut oil• Refined hazelnut oil• Organic hazelnut oil

Typical propertiesAcid value 0.6 max (refined)Iodine value 85 - 97Saponification value 188 - 195Relative density @ 15.5°C 0.912 - 0.917Refractive index @ 20°C 1.467 - 1.474

Typical fatty acid profilePalmitic C16 5 - 9%Palmitoleic C16:1 0.5% maxStearic C18 1 -4%Oleic C18:1 66 - 83%Linoleic C18:2 8 - 25%Linolenic C18:3 0.6% max

Registration informationINCI name Corylus Avellana (Hazel) Seed OilCAS number 68956-68-3EINECS number 273-313-5



John L Seaton & Co LtdFirst Floor 7 Waterside Business Park Livingstone RoadHessle East Yorkshire HU13 OEG United KingdomTel + 44(0)1482579700 Fax + 44(0)1482647313Website www.croda.com/seatonsEmail [email protected]


Specification

Product Seatons Refined Hazlenut Oil

Description Speciality vegetable oil


Test Range MethodMm Max

Colour - 25 Yellow 2.5 Red Lovibond 5.25” cell

Saponification value (mgKOH/g) 187 197 BS 684 : Section 2.6

Peroxide (meqO2lkg) - 10.0 BS 684: Section 2.14

Free fatty acid content (% as oleic) - 0.2 BS 684 : Section 2.10

Iodine value (g12/1 COg) 83 90 BS 684: Section 2.13

Fatty acid profile GLC


C16:1 Palmitoleic acid - 1.0%

018:0 Stearic acid 2.0 6.0%

018:1 Oleic acid 68 85%

C18:2 Linoleic acid 7.0 15.0%

018:3 Linolenic acid - 0.5%


Date of issue: May 2010


Non-warrantyThe information in this publication in belieued to be accurate and is given in good faith but no representation or warranty as to its completeness or accuracy is made.Suggestions for uses or applications are only opinions. Users are responsible for determining the suitability of these products for their own particular purpose.No representation or warranty, eupress or implied, is made with respect to information or products including without limitation warranties of merchantability or fitnessfor a particular purpose or non-infringement of any third party patent or other intellectual property rights including without limit copyright, trademark and designs.Any trademarks identified herein are trademarks of the Croda group of companies.

John L Seaton & Co UmitedFirst Floor 7 Waterside Business Park Livingutone RoadHessle East Yorkshire HU 13 OEG EnglandTel +44 (0)1482 579700 Fax +44 (0)1482 6473 13Website www.seatons-uk.co.ukEmail enquiries@seatons_uk.co.uk


Seatons Macadamia Oil

OriginMacadamia oil is the oil extracted from the nuts of the macadamia tree (Macadamiaternifolia). The oil is a golden yellow colour, which after refining becomes pale yellow.

Characteristics and applicationsMacadamia oil is unique in that it contains a high percentage of palmitoleic acid. It is ahighly emollient oil with anti-ageing properties and is a good conditioning agent for dry andmature skin. It is easily absorbed into the skin and promotes skin suppleness. The oil canbe used in a wide range of skin preparations and sun care products.

Range available

• Cold pressed macadamia oil• Refined macadamia oil• Organic macadamia oil

Typical propertiesFree fatty acids 0.5 MaxIodine value 70 - 80Saponification value 190 -200Relative density20°C 0.911 -0.918

Refractive index @ 20°C 1.466 - 1.470Required HLB value 7

Typical fatty acid profilePalmitic C16 7.5 - 10%Palmitoleic C16:1 16—24%Stearic C18 2-4%Oleic C18:1 53-67%Linoleic C18:2 1.5-4%Linolenic C18:3 0.5% maxArachic C20 1.5 — 3%Gadoleic C20:1 1.5 — 3%Others 7% max

Monounsaturated fatty acids 82%Saturated fatty acids 14%Polyunsaturated fatty acids 4%Trans fatty acids 0

Registration informationINCI name Macadamia Ternifolia Seed OilCAS number 128497-20-1 and 129811-19-4EINECS number 273-313-5



John L Seaton & Co LtdFirst Floor 7 Waterside Business Park Livingstone RoadHessle East Yorkshire HU13 OEG United KingdomTel + 44(0)1482 579700 Fax + 44(0)1482647313Website www.croda.com/seatonsEmail [email protected]


Product

Description


Seatons Refined Macadamia Oil

Speciality vegetable oil

P9014

RangeMm Max

Clear light yellow oil

10.0

Date of issue: January 2010

Non-warrantyThe informahon in this publication is believed to be accurate and is given in good faith but no representation or warranty as to its completeness or accuracy is made.Suggestions for uses or applications are only opinions. Users are responsible for determining the suitability of these products for their own particular purpose.No representation or warranty, eopress or implied, is made with respect to information or products including without limitation warranties of merchantability or fitnessfor a particular purpose or noninfringenient of any third party patent or other intellectual property rights including without limit copyright, trademark and designs.Any trademarks identified herein are trademarks of the Crude group of companies,

John L Seaton & Co UmitedFirst Floor 7 Waterside Business Park Livingstone RoadHessle East Yorkshire HU 13 OEG EnglandTel +44 (0)1482 579700 Fax +44 (0)1482 647313Website www.seatons-uk.co.ukEmail enquiries@seatons_uk.co.uk

Specification

JLS specification number

Test Method

Appearance Visual

Peroxide (meqO2lkg) BS 684 : Section 2.14

Free fatty acid content (% as oleic) 1.0 BS 684: Section 2.10

Iodine value (g12/lOOg) 62 82 BS 684: Section 2.13

Fatty acid profile GLC


C16:1 Palmitoleic acid 12.0 25.0%

C18:0 Stearicacid 0.5 8.0%

C18:1 Oleic acid 50.0 67.0%

C18:2 Linoleic acid - 5.0%

C20:0 Arachidic acid - 5.0%



Seatons Kukul Nut Oil

OriginKukui nut oil is pressed from the nuts of the tropical kukul nut tree (Aleurites molucana).These tree grow mainly in Hawaii, Indonesia and Malaysia and are also known ascandle/candleberry, kemiri nut, lumbang and varnish trees.

Characteristics and applicationsThe Hawaiians have used kukui nut oil for centuries to protect and heal skin that isexposed to the sun, wind and salt water. The oil is high in essential fatty acids and iseasily absorbed by the skin where it softens, moisturises and helps soothe and renew dry,mature, sunburnt, sensitive and problem skin. Kukui nut oil is especially useful in facialskin care products as it is light, non greasy and is said to be able to penetrate the stratumcorneum leaving a semi permeable barrier containing both saturated and unsaturated fattyacids. It is also a good choice of oil for bar soaps, bath gels, massage and baby careproducts.

• Pressed kukui nut oil• Refined kukui nut oil

Typical propertiesAppearanceFree fatty acidsIodine valueSaponification valueRelative density @ 15.5°CRefractive index @ 20°C

Clear yellow liquid2% max (refined grade)130 - 175185-2100.920 - 0.9401.470-1.480

Typical fatty acid profilePalmitic C16Stearic C18Oleic C18:1Linoleic C18:2Alpha LinoIenicCl8:3

5-8%2 - 5%15- 30%35 - 45%24 - 34%

Registration informationINCI nameCAS numberEINECS number

Aleurites Moluccana Seed Oil8015-80-3 & 68956-68-3273-313-5

Specification and MSDS are available on request.

Non-warrantyInformation in this leaflet is given in good faith. John L Seaton & Co Ltd and its associate companies cannot assumeany liability expressed or implied in the presentation of this data, nor should information contained herein be construedas granting licence to practise any methods or compositions of matter covered by British or other patents. Details arecorrect at the date of issue (June 2006).

John L Seaton & Co LtdFirst Floor 7 Waterside Business Park Livingstone RoadHessle East Yorkshire HU13 OEG United KingdomTel + 44(0)1482 579700 Fax + 44 (0)1 482 647313Website www.croda.com/seatonsEmail [email protected]

Range available


Specification

Product

Description

JLS specification number J9073-00

Test

Physical status @ 25°C

Colour

Peroxide value meqO2lkg

Acid value

Unsaponifiable matter

Density @ 20°C

Refractive Index

Iodine value g12/100g

Saponification value mgKOH/g

Typical fatty acid profile

C16:0 Palmitic

C16:1 Palmitoleic

C18:0 Stearic

C18:1 Oleic

C18:2 Linoleic

C18:3 x-Linolenic

C20:0 Arachidic

C20:1 Eicosenoic

Max

Liquid

Light yellow

5.0

1.0

1.0%

0.930

1.480

175

210

7.0%

0.5%

0.1%

35.0%

50%

40.0%

1.5%

1.0%

Method

Visual

Visual

AOCS Cd3a-63

ASTM D1298-85

ASTM D1248-92

AOCS Tg2a-64

ISO 3657-1 988

Issued byAuthorised by

S M PritchardP A Bentley

Non-warrantyInformation in this leaflet is given in good faith. John L Seaton & Co Ltd and its associate companies cannot assume anyliability expressed or implied in the presentation of this data, nor should information contained herein be construed asgranting licence to practise any methods or compositions of matter covered by British or other patents. Specificationdetails are correct at the date of issue.

Updated April 2006

John L Seaton & Co limitedFirst Floor, 7 Waterside Business Park. Livingstone RoadHessle, East Yorkshire, HU 13 OEG, United KingdomTel + 44(0)1482579700 Fax + 44(0)1482647313Website: www.croda.com/seatonsEmail: [email protected]

I

Seatons Refined Kukui Nut Oil

Speciality vegetable oil

RangeMm

0.920

1.470

130

185

6.0%

10.0%

35%

25.0%

Supplied under a quality systemregistered to ISO 9001 :2000


Seatons Sweet Almond OilOriginSweet almond oil is the fixed oil extracted from the kernels of almonds (Prunus amygdalusdulcis), which are commonly grown in Mediterranean countries and the west coast ofAmerica. It is also known as almond oil. The kernels are mechanically pressed and thekernels yield 40-50% oil. This oil can then be refined to give a pale yellow, viscous oil witha characteristic mild odour and taste.

Characteristics and applicationsSweet almond oil is rich in oleic and linoleic fatty acids and also contains vitamins A, Bi,B2 and B6 as well as a small amount of vitamin E. It is widely used in cosmeticformulations as a skin conditioning agent due to its penetrating, smoothing, softening andmoisturising properties. As it can protect and nourish a wide range of skin types and cancalm irritations caused by eczema it is an excellent choice of ingredient for moisturisingpreparations. The oil is also reported to be particularly good at treating dry, brittle nails.As sweet almond oil blends well with many other oils and is a good general lubricating oilit is ideal for use as a massage oil and a carrier oil for aromatherapy.

Range available

• Refined almond oil cosmetics blend• Refined almond oil which conforms to BP and EP specifications• Organic almond oil

Typical propertiesFree fatty acids 1% maxIodine value 93-105Saponification value 185-195Relative density @ 20°C 0.911-0.920Refractive index @ 20°C 1.467-1.473Colour, Lovibond 5.25” cell 3.5R maxRequired HLB value 7

Typical fatty acid profilePalmitic C16 6%Stearic C18 3%Oleic C18:1 69%Linoleic C18:2 17%Linolenic C18:3 0.4%

Registration informationINCI name Prunus Amygdalus Dulcis OilCAS number 8007-69-0EINECS number 273-313-5

Specifications, MSDS and starting formulations are available on request.

Non-warrantyInformation in this leaflet is given in good faith. John L Seaton & co Ltd and its associate companies cannot assumeany liability expressed or implied in the presentation of this data, nor should information contained herein be construedas granting licence to practise any methods or compositions of matter covered by British or other patents. Details arecorrect at the date of issue (April 2005).

John L Seaton & Co LtdFirst Floor 7 Waterside Business Park Livingstone RoadHessle East Yorkshire HU13 OEG United KingdomTel + 44 (0)1 482 579700 Fax + 44 (0)1 482 647313Website www.croda.com/seatonsEmail [email protected]


Specification

Product Seatons Refined Sweet Almond Oil Cosmetic Blend

Appearance

Specific gravity @ 20°C

Refractive Index @ 20°C

Saponification value (mgKOH/g)

Peroxide (meqO2lkg)

Acid value (mgKOH/g)

Iodine value gl2/lOOg

Fatty acid profile (main acids)

C16:0 Palmitic acid

C16:1 Palmitoleic acid

C18:0 Stearic acid

C18:1 Oleic acid

C18:2 Linoleic acid

C18:3 Linolenic acid

C20:0 Arachidic acid

C20:1 Gadoleic acid

C22:0 Behenic acid

C24:0 Lignoceric acid

Mm Max

Clear, light yellow liquid

0.910 0.930

1.465 1.475

185 200

10.0

0.5

95 109

9.0%

2.0%

3.0%

75.0%

30.0%

0.5%

0.3%

0.3%

0.8%

0.5%

Method

Visual

BS 718

BS 684: Section 1.2

BS 684: Section 2.6

BS 684: Section 2.14



GLC


Date of issue: October 2009

Non-warrantyThe information In this publication is believed to be accurate and is given in good faith but no representation or warranty as to its completeness or accuracy is macfeSuggestions for uses or applications are only opinions. Users are responsible for determining the suitability of these products for their own particular purpose.No representation or warranty, express or implied, is made with respect to information or products including without limitation warranties of merchantability or fitnessfor a particular purpose or non-infringement of any third party patent or other intellectual property rights induding without limit copyright, trademark and designs.My trademarks identified herein are trademarks of the Croda group of companies.

John L Seaton & Co UmitedFirst Floor 7 Waterside Business Park Livingstone RoadHessle East Yorkshire HU 13 OEG EnglandTel +44 (0)1482 579700 Fax +44 (0)1482 647313Website www.seatons-uk.co.ukEmail etnquiries©seatons-uk.co.uk

Description

Test


A blend of refined sweet almond oil and other refined vegetable oils

Range

3.0

1.0

60.0

20.0

Supplied Under a quality management system registered to ISO 9001



Memorandum


FROM: John Bailey, Ph.D.Industry Liaison to the Cifi Expert Panel

DATE: July 26, 2010

SUBJECT: Updated Concentration of Use Butyrospermum Parkii (Shea) Butter

The 80% face product in the original table is actually a mask that is diluted to 30% ButyrospermumParkii (Shea) Butter before use. The attached updated table reflects this change.

1101 17th Street, N.W., Suite 30O Washington, D.C. 20036-4702 202.331.1770 202.331.1969 (fax) www.personalcarecouncil.org CIR Panel Book Page 216

Concentration of Use - Butyrospermum Parkii (Shea) Butter, Butyrospermum Parkii (Shea)Butter Extract, Butyrospermum Parkii (Shea) Butter Unsaponifiables, Butyrospermum Parkii(Shea) Nut Extract, Butyrospermum Parkii (Shea) Nut Shell Powder, Butyrospermum Parkii

(Shea) Oil, Butyrospermum Parkii (Shea) Seedcake Extract, Coco/Shea Butter Glycerides,Hydrogenated Shea Butter, Hydrolyzed Shea Seedcake Extract, PEG-50 Shea Butter, PEG-60 Shea

Butter Glycerides, PEG-75 Shea Butter Glycerides, Polyglyceryl-4 Almondate/Shea Butterate,Polyglyceryl-3 Soyate/Shea Butterate, Shea Butteramide/Castoramide DEA, Shea Butter CetylEsters, Shea Butter Decyl Esters, Shea Butter Glycereth-8 Esters, Shea Butter Glyceride, Shea

Butter Glycerides, Shea Butter Oleyl Esters, Shea Butter PEG-12 Dimethicone Esters, Shea ButterPEG-8 Esters and Shea Butter Polyglyceryl-6 Esters*

Ingredient Product Category Concentrationof Use

Butyrospermum Parkii (Shea) Butter Baby lotions, oils powders and 0.1-5%creams

Butyrospermum Parkii (Shea) Butter Other baby products 0.0 1-0.3%

Butyrospermum Parkii (Shea) Butter Bath oils, tablets and salts 1%

Butyrospermum Parkii (Shea) Butter Eyebrow pencil 0.1-6%

Butyrospermum Parkii (Shea) Butter Eyeliner 0.1-8%

Butyrospermum Parkii (Shea) Butter Eye shadow 0.5-6%

Butyrospermum Parkii (Shea) Butter Eye lotion 0.5-7%

Butyrospermum Parkii (Shea) Butter Mascara 0.5%

Butyrospermum Parkii (Shea) Butter Perfumes 0.2-0.8%

Butyrospermum Parkii (Shea) Butter Other fragrance preparations 0.00 1-1%

Butyrospermum Parkii (Shea) Butter Hair conditioners 0.0005-1%

Butyrospermum Parkii (Shea) Butter Hair straighteners 0.1-1%

Butyrospermum Parkii (Shea) Butter Shampoos (noncoloring) 0.001-1%

Butyrospermum Parkii (Shea) Butter Tonics, dressings and other hair 0.1-2%grooming aids

Butyrospermum Parkii (Shea) Butter Other hair preparations 0.5-3%(noncoloring)

Butyrospermum Parkii (Shea) Butter Blushers (all types) 0.1-1%

Butyrospermum Parkii (Shea) Butter Face powders 0.2-2%

Butyrospermum Parkii (Shea) Butter Foundations 0.4-20%

Page 1 of 6


Butyrospermum Parkii (Shea) Butter Leg and body paints 6%

Butyrospermum Parkii (Shea) Butter Lipstick 0.5-26%

Butyrospermum Parkii (Shea) Butter Other makeup preparations1 1-6%

Butyrospermum Parkii (Shea) Butter Cuticle softener 18-60%

Butyrospermum Parkii (Shea) Butter Nail creams and lotions 2-25%

Butyrospermum Parkii (Shea) Butter Nail polish and enamel 0.05%

Butyrospermum Parkii (Shea) Butter Nail polish and enamel removers 3%

Butyrospermum Parkii (Shea) Butter Other manicuring preparations 0.01%

Butyrospermum Parkii (Shea) Butter Bath soaps and detergents 0.003-3%

Butyrospermum Parkii (Shea) Butter Deodorants (underarm) 1%

Butyrospermum Parkii (Shea) Butter Other personal cleanliness products2 0.1-5%

Butyrospermum Paridi (Shea) Butter Aftershave lotions 0.2-4%

Butyrospermum Parkii (Shea) Butter Shaving cream (aerosol, brushless 0.0 1-2%and lather)

Butyrospermum Parkii (Shea) Butter Skin cleansing (cold creams, 0.03-10%cleansing lotions, liquids and pads)

Butyrospermum Parkii (Shea) Butter Depilatories 0.3%

Butyrospermum Parkii (Shea) Butter Face and neck creams, lotions and 0.04-19%powders

Butyrospermum Parkii (Shea) Butter Body and hand creams, lotions and 0.4-45%powders

Butyrospermum Parkii (Shea) Butter Body and hand sprays 1%

Butyrospermum Parkii (Shea) Butter Foot powders and sprays 1-3%

Butyrospermum Parkii (Shea) Butter Moisturizing creams, lotions and 0.003-11%powders

Butyrospermum Parkii (Shea) Butter Night creams, lotions and powders 0.03-6%

Butyrospermum Parkii (Shea) Butter Paste masks (mud packs) 0.1-30%

Butyrospermum Parkii (Shea) Butter Other skin care preparations 0.01-16%

Butyrospermum Parkii (Shea) Butter Suntan gels, creams, and liquids 0.5-8%

Butyrospermum Parkii (Shea) Butter Indoor tanning preparations 2%

Page 2 of 6


Butyrospemum Paridi (Shea) Butter Other suntan preparations ]_1%

Butyrospermum Parkii (Shea) Butter Extract Bath oils, tablets and salts 0.03%

Butyrospermum Parkii (Shea) Butter Extract Bubble baths 1%

Butyrospermum Parkii (Shea) Butter Extract Other bath preparations 0.03-1%

Butyrospermum Parkii (Shea) Butter Extract Eyebrow pencil 0.2%

Butyrospermum Parkii (Shea) Butter Extract Eye lotion 0.5-2%

Butyrospermum Parkii (Shea) Butter Extract Hair conditioners 0.0 1%

Butyrospermum Parkii (Shea) Butter Extract Tonics, dressings and other hair 1%grooming aids

Butyrospermum Parkii (Shea) Butter Extract Other hair preparations 1%(noncoloring)

Butyrospermum Parkii (Shea) Butter Extract Foundations 0.009%

Butyrospermum Parkii (Shea) Butter Extract Lipstick 0.1-6%

Butyrospermum Parkii (Shea) Butter Extract Nail creams and lotions 0.0 1%

Butyrospermum Parkii (Shea) Butter Extract Bath soaps and detergents 0.03-1%

Butyrospermum Parkii (Shea) Butter Extract Deodorants (underarm) 0.03%

Butyrospermum Parkii (Shea) Butter Extract Preshave lotions (all types) 0.03%

Butyrospermum Parkii (Shea) Butter Extract Skin cleansing (cold creams, 0.006-1%cleansing lotions, liquids and pads)

Butyrospermum Parkii (Shea) Butter Extract Depilatories 0.0 1-0.3%

Butyrospermum Parkii (Shea) Butter Extract Face and neck creams, lotions and 2%powders

Butyrospermum Parkii (Shea) Butter Extract Body and hand creams lotions and 0.02-5%powders

Butyrospermum Parkii (Shea) Butter Extract Body and hand sprays 0.5-1%

Butyrospermum Parkii (Shea) Butter Extract Other skin care preparations 0.3%

Butyrospermum Parkii (Shea) Butter Extract Suntan gels, creams and liquids 0.1%

Butyrospermum Parkii (Shea) Butter Extract Other suntan preparations 0.5%

Butyrospermum Parkii (Shea) Butter Eyebrow pencil 0.2%Unsaponifiables

Butyrospermum Parkii (Shea) Butter Eyeliner 0.7%

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Unsaponifiables

Butyrospermum Parkii (Shea) Butter Eye shadow 0.4%Unsaponifiables

Butyrospermum Parkii (Shea) Butter Other hair preparations 2%Unsaponifiables (noncoloring)

Butyrospermum Parkii (Shea) Butter Blushers (all types) 0.06%Unsaponifiables

Butyrospermum Parkii (Shea) Butter Face powders 0.2-1%Unsaponifiables

Butyrospermum Parkii (Shea) Butter Lipstick 1-3%Unsaponifiables

Butyrospermum Parkii (Shea) Butter Rouges 0.06%Unsaponifiables

Butyrospermum Parkii (Shea) Butter Face and neck creams, lotions and 3%Unsaponifiables powders

Butyrospermum Parkii (Shea) Butter Body and hand creams, lotions and 1%Unsaponifiables powders

Butyrospermum Parkii (Shea) Butter Night creams, lotions and powders 2%Unsaponifiables

Butyrospermum Parkii (Shea) Butter Other skin care preparations 2%Unsaponifiables

Butyrospermum Parkii (Shea) Oil Bath oils, tablets and salts 1%

Butyrospermum Parkii (Shea) Oil Bubble baths 1%

Butyrospermum Parkii (Shea) Oil Lipstick 15%

Butyrospermum Parkii (Shea) Oil Other manicuring preparations 0.01-1%

Butyrospermum Parkii (Shea) Oil Bath soaps and detergents 0.6%

Butyrospermum Parkii (Shea) Oil Aftershave lotions 1%

Butyrospermum Parkii (Shea) Oil Skin cleansing (cold creams, 1%cleansing lotions, liquids and pads)

Hydrogenated Shea Butter Other personal cleanliness products 1%

Hydrogenated Shea Butter Skin cleansing (cold creams, 1%cleansing lotions, liquids and pads)

Hydrogenated Shea Butter Body and hand creams, lotions and 1%

Page 4 of 6


powders

Hydrogenated Shea Butter Other skin care preparations 1%

PEG-50 Shea Butter Other baby products3 0.1%

PEG-50 Shea Butter Bath oils, tablets and salts 2%

PEG-50 Shea Butter Hair conditioners 0.00 1%

PEG-50 Shea Butter Shampoos (noncoloring) 0.001%

PEG-50 Shea Butter Other hair preparations 0.001%(noncoloring)

PEG-50 Shea Butter Other personal cleanliness products4 3%

PEG-50 Shea Butter Skin cleansing (cold creams, 3%cleansing lotions, liquids and pads)

PEG-50 Shea Butter Face and neck creams, lotions and 0.1%powders

PEG-50 Shea Butter Body and hand creams, lotions and 0.1-1%powders

PEG-50 Shea Butter Paste masks (mud packs) 0.1 %

PEG-50 Shea Butter Skin fresheners 2%

PEG-75 Shea Butter Glycerides Bubble baths 1%

PEG-75 Shea Butter Glycerides Other fragrance preparations 0.5%

PEG-75 Shea Butter Glycerides Hair conditioners 0.1%

PEG-75 Shea Butter Glycerides Shampoos (noncoloring) 0.3%

PEG-75 Shea Butter Glycerides Tonics, dressings and other hair 0.02%grooming aids

PEG-75 Shea Butter Glycerides Bath soaps and detergents 0.1-3%

PEG-75 Shea Butter Glycerides Douches 0.1%

PEG-75 Shea Butter Glycerides Skin cleansing (cold creams, 1%cleansing lotions, liquids and pads)

PEG-75 Shea Butter Glycerides Face and neck creams, lotions and 0.1%powders

PEG-75 Shea Butter Glycerides Body and hand creams, lotions and 0.002-1%powders

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Shea Butter Glycerides Lipstick

Shea Butter Glycerides Skin cleansing (cold creams,cleansing lotions, liquids and pads)

*Ingredients included in the title of the table, but not found in the table were included in the survey, butno uses were reported.11% in a face highlighter21% in a shower gelO. 1% in a rinse-off product43% in a hand scrub

Information collected in 2009Table prepared September 17, 2009

Updated July 26, 2010

Page 6 of 6



Memorandum


FROM: John Bailey, Ph.D 3-(ri Ii’Industry Liaison to the CIR Expert Panel

DATE: July 19, 2010

SUBJECT: Comments on the Scientific Literature Review of Nut Oils

pA - In the Introduction, please change “as they are used in cosmetic ingredients.” to “as they are usedin cosmetic products.”

p.4 - In the Introduction, please change “triglycerides composed of mixtures of fatty acids” to“triglycerides containing various fatty acids”.

p.4- - At the start of the Chemistry section, please clarify what is meant by “The group”. Fats and oilsare not just derived from plants as this paragraph seems to imply.

p.8 - Is it correct to call all the oils in this report “edible”?p.8 - Unless there was evidence of dermal absorption of Prunus Amygdalus Dulcis (Sweet Almond)

Oil, please change “percutaneous absorption” to “percutaneous exposure”.p.10 - Please indicate the number guinea pigs and types of assays, e.g., maximization, in which the

sensitization potential of Cocos Nucifera (Coconut) Oil and Hydrogenated Coconut Oil wasstudied. If studies were done on both substances, both substances should be in the subsectionheading.

p.10 - Please provide the type of in vitro studies that were used to study the potential ocular effects ofAleurites Moluccana Seed Oil. What species was used in the in vivo study?

p.12 - As Singh et al. (2004) (reference 41) completed a tumor promotion study, did they include aconclusion regarding the tumor promoting potential of Anacardium Ocidentale (Cashew) SeedOil?

p.14- - The following is not a complete sentence. “A bar soap contining 13% coconut oil evaluated forskin irritation using standard Draize procedures.”

p.15 - It would be helpful to indicate the number of subjects treated with cosmetic formulationscontaining 25% Prunus Amygdalus Dulcis (Sweet Almond) Oil.

p.17, Item 5 - As the oils are triglycerides not mixtures of fatty acids, having irritation and sensitizationtesting of individual fatty acids is not necessary. If irritation and sensitization data on the fattyacids is needed, CIR staff should look for published information. Searching PubMed forLinolenic Acid and sensitization the following was the first reference identified.

Kreilling R, Hollnagal HM, Hareng L, et al. 2008. Comparison of the skin sensitizationpotential of unsaturated compounds as assessed by the murine local lymph node

1101 17th Street, N.W., Suite 300 Washington, D.C. 20036-4702 202.331.1770 202.331.1969 (fax) www.personalcarecouncil.org CIR Panel Book Page 219

assay (LLNA) and the guinea pig maximization test (GPMT). Food ChemicalToxicology 46(6): 1896-1904.

p.17 - Request 6 is not clear. If this review is focused only on the composition of the ingredients andthe dermal effects of the ingredients, why is “any other information that pertains to the safety ofuse in cosmetics” necessary? Requests to industry should reflect the same criteria CIR staffused for identifying information in the published literature. If all types of safety information areneeded from industry, CIR staff need to go back and identify all the relevant published safetyinformation on these oils.

2
