class 12- sleep disorders

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SLEEP DISODERS

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Page 1: Class 12- Sleep Disorders

SLEEP DISODERS

Page 2: Class 12- Sleep Disorders

Americans

• 62% have sleep problems once wkly or more

• 40% sleepy enough during the day to interfere with activities

• 62% drive while drowsy• 27% have fallen asleep while

driving• 60% children feel parents are tired

during the day• 15% children admit falling asleep

at school

Page 3: Class 12- Sleep Disorders

Women• 79% report sleep disturbance during

pregnancy• 36% peri-menopausal women have

disturbed sleep• 25% suffer from significant daytime

sleepiness• 30% disturbed sleep interferes with daily

activity, 27% job performance is impaired• 24% say sleep gets in the way of caring

for family

Males1/3 of men get less than 6 hours sleep (during week)

Page 4: Class 12- Sleep Disorders

COMORBIDITIES

• 40-45% of those with insomnia & hypersomnia have another Axis I disorder

• Mood Disorders – 4x higher • Anxiety Disorders • Schizophrenia • Substance abuse

Page 5: Class 12- Sleep Disorders

Normal Sleep

• Normal Sleep patterns (cycles)• Non REM• REM• Circadian rhythm • Drugs influence on sleep• Genetics of sleep

Page 6: Class 12- Sleep Disorders

Sleep DisorderPhysiology of sleep • Sleep Stages

– NREM Sleep – REM Sleep

• Sleep-Regulating Processes – Circadian Rhythm

•Endogenous vs. exogenous factor– Homeostasis

•Balance o f sleep and awake

Page 7: Class 12- Sleep Disorders

Influences on Sleep • Developmental Changes

– Newborns and Infants – Children – Adolescents – Young and Middle Adults – Older Adults – myth

• Amount of sleep=F (genetics, preferences, lifestyle, environment)

Page 8: Class 12- Sleep Disorders

Influences on Sleep (Cont’d)

• Medical Disorders and Treatments i.e.. Asthma, hyperthyroidism, COPD

• Drugs and Chemical Substances i.e. alcohol, lithium, cocaine-> CNS was affected

• Jet lag

Page 9: Class 12- Sleep Disorders

Sleep Disorders • Etiology• Signs and Symptoms/Diagnostic

Criteria • Dyssomnias: abnormalities in the

amount, quality, or timing of sleep – Narcolepsy– breathing-related sleep disorders– periodic limb movement disorder– insomnia

• Parasomnias: abnormal behavioral or physiological events associated with sleep– sleepwalking – tooth grinding

Page 10: Class 12- Sleep Disorders

DYSSOMNIAS

Page 11: Class 12- Sleep Disorders

PRIMARY INSOMNIA• difficulty initiating and maintaining

sleep • awakenings that occur much earlier

than desired • sleep that is non-restorative and of

poor quality • result in impairment in daytime

function.

Page 12: Class 12- Sleep Disorders

• Prevalence rates are higher in women and increase with age.

• Associated with reduced quality of life, mood disorders and increased health services usage

• Represents a significant economic burden in the US, with estimated direct costs of $13.9 billion annually.

Page 13: Class 12- Sleep Disorders

– Change in sleep environments– Jet lag– Changes in work shift– Excessive noise– Unpleasant room temperature– Stressful life events– Medical condition– Medications– Poor sleep hygiene

Causes of Insomnia

Page 14: Class 12- Sleep Disorders

Behavioral Model of Insomnia

• Insomnia occurs acutely in relation to both predisposing and precipitating factors

• The chronic form of the disorder is maintained by maladaptive coping behaviors.

• A state of “conditioned arousal” may develop in which situations associated with sleep become alerting rather than relaxing- further impairing sleep.

Page 15: Class 12- Sleep Disorders

Insomnia Cycle

MALADAPTIVE HABITS•Excessive time in bed•Irregular sleep schedule•Daytime napping•Sleep- incompatible activities

AROUSAL•Emotional•Cognitive

•Physiologic

DYSFUNCTIONAL COGNITIONS•Worrying over sleep loss

•Ruminating over consequences•Unrealistic Expectations

CONSEQUENCES•Mood Disturbances

•Fatigue•Performance impairments

•Social Discomfort

Page 16: Class 12- Sleep Disorders

Cognitive Behavioral Therapy for Insomnia

• change poor sleep habits and faulty beliefs about sleep

• promote good sleep hygiene

THROUGH…….• sleep restriction, stimulus control,

relaxation techniques, education and good sleep practices.

Page 17: Class 12- Sleep Disorders

• CBT is as successful as medications in the acute treatment (4-8 weeks) of insomnia.

• It is more effective than medications in the long term.

• Average of 50-60% improvement• Long term studies reveal a sustained

improvement in sleep quality and duration.

• Patients continued to experience improvement over follow-up periods of >1year.

Page 18: Class 12- Sleep Disorders

Other Treatments

• Pharmacologic therapy– Benzodiazepines / related

hypnotics– Antidepressants– Antihistamines– Melatonin

• Light

Page 19: Class 12- Sleep Disorders

BREATHING-RELATED SLEEP DISORDER• Unlike people with insomnia, this is a

structural/ anatomical problem with physiological consequences

• Treatment with oral appliance or surgery is needed

• Sleep maintenance, sleep walking, or other consequences are generally relieved after treatment but…..

• Co-occurring sleep disorders may need psychological treatment.

Page 20: Class 12- Sleep Disorders

Sleep Apnea

• Obstructive sleep apnea– Clinical manifestations

• Central sleep apnea– Restrictive lung disease– Neuromuscular disease– Cardiac– Neurological

Page 21: Class 12- Sleep Disorders

Other sleep disorders

Narcolepsy

– Genetic Aspects of narcolepsy– Irresistible attacks of refreshing sleep

daily for 3 months– Diagnosis

• Cataplexy- brief periods of loss of muscle tone

• REM disordered transitions- can report hallucinations, sleep paralysis at transitions between wakefulness and sleep

– Treatment of narcolepsy• Stimulants, REM suppressants • Behavioral adjustments

Page 22: Class 12- Sleep Disorders

Circadian Rhythm Sleep Disorder

• Causes insomnia because of a lack of synchronization between an individual’s internal clock and the external schedule

• Treatment is best accomplished with chronotherapy and/ or phototherapy

Page 23: Class 12- Sleep Disorders
Page 24: Class 12- Sleep Disorders

Specifiers

• Delayed Sleep Type- late sleep onset & late awakening

• Shift Work Type

• Unspecified Type

• Jet Lag Type……

Page 25: Class 12- Sleep Disorders

… Jet Lag Type

• Use activities (eating, exercise, sightseeing) and exposure to light to try to synchronize body rhythms with those of the new environment

• Melatonin 3 mg about 30 minutes before bedtime on the day of travel and for up to four days after arrival is appropriate

• A dose of 0.5 mg has less effect on sleep, but otherwise helps adaptation similarly

• Adult travelers crossing five or more time zones are likely to benefit from melatonin

Page 26: Class 12- Sleep Disorders

DYSSOMNIA NOS

• Environmental Issues

• “Restless Legs Syndrome”

• Periodic Limb Movements

Page 27: Class 12- Sleep Disorders

PARASOMNIAS

Page 28: Class 12- Sleep Disorders

Parasomnias

• Sleep disorders characterized by abnormal behavioral or physiological events which occur during sleep or during sleep-wake transitions.

• Parasomnias typically do not cause insomnia or excessive sleepiness

Page 29: Class 12- Sleep Disorders

• Sleep Terror- awakening with fear, dream amnesia and unresponsiveness VS.

• Nightmare- awakening with detailed threatening dream recall with rapid alertness

• Sleepwalking- activities without responsiveness and difficulty awakening

• NOS

Page 30: Class 12- Sleep Disorders

GMC and Sleep

• Parkinsonism• Neuromuscular disease• Respiratory disease• Dementia• Epileptic seizures• Cardiovascular disease