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Pathologies Clinical Perspectives on Disease and Disorder

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A review of ebola, teratomas and gingivitis

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Page 1: Clinical Cases

PathologiesClinical Perspectives on Disease and Disorder

Page 2: Clinical Cases

Presenters• Hasan Mohammad: Teratoma (Etiology, Prophylaxis, Intervention)

• Ahmed Musa: Ebola (Causes, Risks, Prevention)

• Tarek Kanawati: Gingivitis ( Causes, Risks, Prevention)

Page 3: Clinical Cases

Teratoma-Nature and Etiology• Teratomas belong to a class of

tumors that present in almost any region of the body, often containing tissues not usually found in that area.

• The indications may include hair, teeth, nail, bone or in even rarer cases limbs.

• Teratomas are congenital, meaning they are conditions present from birth.

• On an epidemiological basis, Teratomas may arise in as many as 1 in 40,000 births.

Page 4: Clinical Cases

Teratoma-Risk Factors• Given the diagnosis and nature of

teratomas, risk factors are rather difficult to pinpoint.

• Many theories have been proposed, some scientifically sound; others based on speculation.

• The risk of a child developing a teratoma in later life is rather marginal, but this may increase if a previous teratoma was present.

• A genetic risk factor is also readily indicated, especially inheritable mutations.

Page 5: Clinical Cases

Teratoma-Prevention/Prophylaxis

• Teratomas are idiopathic, meaning the establishment of their cause is vague or unknown.

• It is unrealistic to suggest a means of prevention due to its genetic and molecular nature compounded with an unpredictable incidence. It is also impractical to indicate a single preventative measure.

• But as the studies regarding the molecular and cytological interplay of teratomas continue, hope may lie at the end of this malignant tunnel.

Page 6: Clinical Cases

EbolaThe Deadly Viral

Hemorrhagic Fever

Page 7: Clinical Cases

Ebola- Nature and Causes• Ebola virus disease is a severe and

often fatal disease in humans and other primates caused by the Ebola virus. It was first found in Ebola River in Republic of the Congo, Africa, which is the reason why it was named ‘Ebola’.

• Ebola is a RNA virus. They need a live host to survive and reproduce.

• Ebola can quickly travel from person to person. It can be spread by direct contact of the body or body fluids.

• Ebola is caused by four of the five viruses of the Ebolavirus genus: Bundibugyo virus (BDBV), Ebola virus (EBOV), Sudan virus (SUDV) and Tai Forest virus (TAFV).

Page 8: Clinical Cases

Ebola- Risks• A person with the Ebola virus

disease will have many symptoms ranging from mild to severe to fatal. These include fever, sore throat, weakness, severe headache, joint and muscle aches, diarrhea, vomiting, dehydration, dry and hacking cough, rashes, red eyes, hiccups and stomach pain.

• More severe cases include external and internal bleeding and haemorrhaging, which is continuous bleeding from the circulatory system.

• Patients with Ebola usually die within the second week of having the disease. The virus stays in the carcass of the body for a few days.

Page 9: Clinical Cases

Ebola- Prevention• There are currently no treatments for

the Ebola virus diseases. A patient with Ebola has a fatality rate of 50-90%. If the patient does not die within the first couple of weeks, the virus will go away.

• There also are currently no vaccines for the virus, so the only methods for preventing the spreading of Ebola is no direct contact and keeping the patients away from the rest of the population.

• However, scientists have recently discovered a protein on the surface of the Ebola virus, which contributes to the attack on blood vessels. Scientists are trying to develop a vaccine or drug aimed at this protein to try to prevent the disease or decrease the severity of the disease.

Page 10: Clinical Cases

Gingivitis The Disease Of The Ancient

Gums

Page 11: Clinical Cases

Gingivitis- Nature and Causes

• Gingivitis is an inflammation of the gums surrounding the teeth.

• Bacteria can cause inflammation of the gums. Although bacteria are normally found in our bodies and provide protective effects most of the time, bacteria can be harmful. The mouth is an ideal place for bacteria to live. The warm, moist environment and constant food supply are everything the bacteria needs.

Page 12: Clinical Cases

Gingivitis-Risk Factors

• The people at risk of gingivitis are people that lack oral hygiene. The lack of oral hygiene encourages the bacterial build up and plaque formation.

• A patient with gingivitis will have red and puffy gums, and they will most likely bleed when they brush their teeth.

• Gum inflammation may occur during ovulation. Progesterone dilates blood vessels causing inflammation, and blocks the repair of collagen.

Page 13: Clinical Cases

Gingivitis-Preventions

• There are not many ways to prevent Gingivitis . Besides going to the dentist for a regular check up, prevention for gingivitis mainly takes place at home.

• The ways to prevent Gingivitis are part of our everyday life. Brush our teeth twice a day, flossing,etc.

• However, people are too lazy to incorporate them in everyday life. It can be prevented by having oral hygiene. This means, brushing your teeth, flossing, etc.

Page 14: Clinical Cases

Conclusion