cns sequence cns histology march 8, 2010. spinal cord dorsal horns: interneurons ventral horns:...

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CNS Sequence CNS Histology March 8, 2010

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Page 1: CNS Sequence CNS Histology March 8, 2010. Spinal cord Dorsal horns: Interneurons Ventral horns: Motor neurons Lateral horns: Sympathetic neurons Parasympathetic

CNS Sequence

CNS Histology

March 8, 2010

Page 2: CNS Sequence CNS Histology March 8, 2010. Spinal cord Dorsal horns: Interneurons Ventral horns: Motor neurons Lateral horns: Sympathetic neurons Parasympathetic

Spinal cord

Dorsal horns: InterneuronsVentral horns: Motor neurons Lateral horns: Sympathetic neurons Parasympathetic (S2-4) neuronsDRG: Sensory (pseudounipolar) neuronsAutonomic ganglia: Post ganglionic neurons with unmyelinated axons. Sympathetic: paravertebral ganglia Parasympathetic: In organs

Page 3: CNS Sequence CNS Histology March 8, 2010. Spinal cord Dorsal horns: Interneurons Ventral horns: Motor neurons Lateral horns: Sympathetic neurons Parasympathetic

65-2 Lumbar Spinal Cord, H&E

D.R.G.

Spinal Cord

Dura mater

Myelinated nerves

Page 4: CNS Sequence CNS Histology March 8, 2010. Spinal cord Dorsal horns: Interneurons Ventral horns: Motor neurons Lateral horns: Sympathetic neurons Parasympathetic

#65-1N Spinal cord and DRG

Ventral horn

Lateral horn

Dorsal horn

Dorsal root ganglion (DRG)

Page 5: CNS Sequence CNS Histology March 8, 2010. Spinal cord Dorsal horns: Interneurons Ventral horns: Motor neurons Lateral horns: Sympathetic neurons Parasympathetic

66a Thoracic Spinal Cord

Ventral median fissure

Dorsal horn

Lateral horn

Ventral horn

Dorsal median sulcus

Page 6: CNS Sequence CNS Histology March 8, 2010. Spinal cord Dorsal horns: Interneurons Ventral horns: Motor neurons Lateral horns: Sympathetic neurons Parasympathetic

66a Thoracic Spinal Cord

Neurons in Lateral Horn

Neurons in ventral Horn

Page 7: CNS Sequence CNS Histology March 8, 2010. Spinal cord Dorsal horns: Interneurons Ventral horns: Motor neurons Lateral horns: Sympathetic neurons Parasympathetic

65-1N Motor neurons, glial cells and neuropil

Glial cells

Neuropil

Page 8: CNS Sequence CNS Histology March 8, 2010. Spinal cord Dorsal horns: Interneurons Ventral horns: Motor neurons Lateral horns: Sympathetic neurons Parasympathetic

Dorsal root ganglion cells

Page 9: CNS Sequence CNS Histology March 8, 2010. Spinal cord Dorsal horns: Interneurons Ventral horns: Motor neurons Lateral horns: Sympathetic neurons Parasympathetic

Cerebrum

Sulcus (sulci) Gyrus (gyri)

Cerebellum

Pons Medulla oblongata

3rd ventricle

4th ventricle

Brain

Page 10: CNS Sequence CNS Histology March 8, 2010. Spinal cord Dorsal horns: Interneurons Ventral horns: Motor neurons Lateral horns: Sympathetic neurons Parasympathetic

Cerebrum and Cerebellum

76b

77

Page 11: CNS Sequence CNS Histology March 8, 2010. Spinal cord Dorsal horns: Interneurons Ventral horns: Motor neurons Lateral horns: Sympathetic neurons Parasympathetic

#77 Cerebellum #76b Cerebrum

W WW

CC

C

W

C: Cortex of gray matter W: White

matter

Page 12: CNS Sequence CNS Histology March 8, 2010. Spinal cord Dorsal horns: Interneurons Ventral horns: Motor neurons Lateral horns: Sympathetic neurons Parasympathetic

#77 Cerebellum

Cortex

White matter

Page 13: CNS Sequence CNS Histology March 8, 2010. Spinal cord Dorsal horns: Interneurons Ventral horns: Motor neurons Lateral horns: Sympathetic neurons Parasympathetic

#77 Cerebellum

Purkinje neurons (cells)

Page 14: CNS Sequence CNS Histology March 8, 2010. Spinal cord Dorsal horns: Interneurons Ventral horns: Motor neurons Lateral horns: Sympathetic neurons Parasympathetic

#77a Cerebellar Cortex

Page 15: CNS Sequence CNS Histology March 8, 2010. Spinal cord Dorsal horns: Interneurons Ventral horns: Motor neurons Lateral horns: Sympathetic neurons Parasympathetic

#76 Cerebrum

Page 16: CNS Sequence CNS Histology March 8, 2010. Spinal cord Dorsal horns: Interneurons Ventral horns: Motor neurons Lateral horns: Sympathetic neurons Parasympathetic

#76

Ross and Pawlina, p.311

Cereb

ral cortex

Page 17: CNS Sequence CNS Histology March 8, 2010. Spinal cord Dorsal horns: Interneurons Ventral horns: Motor neurons Lateral horns: Sympathetic neurons Parasympathetic

Cerebellum Cerebrum

CC

W

W

Purkinje cells (neurons)

C: Cortex of gray matter W: White matter

Page 18: CNS Sequence CNS Histology March 8, 2010. Spinal cord Dorsal horns: Interneurons Ventral horns: Motor neurons Lateral horns: Sympathetic neurons Parasympathetic

Hippocampal Formation

Lateral View Posterior View

Page 19: CNS Sequence CNS Histology March 8, 2010. Spinal cord Dorsal horns: Interneurons Ventral horns: Motor neurons Lateral horns: Sympathetic neurons Parasympathetic

#NP004N Hippocampal regionCA: Cornus ammonis

CA1

CA3

CA2

Dentate gyrusHippocamp

us

Choroid plexus

Page 20: CNS Sequence CNS Histology March 8, 2010. Spinal cord Dorsal horns: Interneurons Ventral horns: Motor neurons Lateral horns: Sympathetic neurons Parasympathetic

3 layers of Hippocampal region

Molecular

layer

Pyramidal cell layer

Polymorphic layer

Pyramidal cells

Page 21: CNS Sequence CNS Histology March 8, 2010. Spinal cord Dorsal horns: Interneurons Ventral horns: Motor neurons Lateral horns: Sympathetic neurons Parasympathetic

3 layers of Dentate gyrus

Mol

ecul

ar

laye

r

Granule cell layer (neurons)

Polymorphic layer Polymorphic layer (interneurons)

Molecular layer (dendrites of granule cells)

Page 22: CNS Sequence CNS Histology March 8, 2010. Spinal cord Dorsal horns: Interneurons Ventral horns: Motor neurons Lateral horns: Sympathetic neurons Parasympathetic

#74 Sympathetic ganglion cells #75 Parasympathetic ganglion cells

Seminal vesicle

Page 23: CNS Sequence CNS Histology March 8, 2010. Spinal cord Dorsal horns: Interneurons Ventral horns: Motor neurons Lateral horns: Sympathetic neurons Parasympathetic

Sensory and Autonomic Neurons (DRG) (Parasympathetic)

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