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May 8, 2020 Listing Department Code: 532321 BSE Limited P J Towers, Dalal Street, Fort, Mumbai – 400001 Listing Department Code: CADILAHC NATIONAL STOCK EXCHANGE OF INDIA LIMITED Exchange Plaza, Bandra Kurla Complex, Bandra (E), Mumbai – 400051 Re.: Press Release Dear Sir / Madam, Please find enclosed a Press Release dated May 8, 2020 titled “Zydus Cadila Launches Enzalutamide, making Prostate Cancer therapy highly affordable”. The contents of the Press Release give full details. Please bring the aforesaid news to the notice of the members of the exchange and investors’ at large. Thanking you, Yours faithfully, For, CADILA HEALTHCARE LIMITED DHAVAL N. SONI COMPANY SECRETARY Encl.: As above Regd. Office : ‘Zydus Corporate Park’, Scheme No. 63, Survey No. 536, Khoraj (Gandhinagar), Nr. Vaishnodevi Circle, S. G. Highway, Ahmedabad 382 481, India. Phone : +91-79-71800000, +91-79-48040000 www.zyduscadila.com CIN : L24230GJ1995PLC025878

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Page 1: Code: CADILAHC NATIONAL STOCK EXCHANGE OF INDIA … · highly effective drug for the treatment of Prostate Cancer, under the brand name ‘Obnyx’ in India. In a step that can significantly

May 8, 2020

Listing Department Code: 532321BSE LimitedP J Towers, Dalal Street, Fort,Mumbai – 400001

Listing Department Code: CADILAHCNATIONAL STOCK EXCHANGE OF INDIA LIMITEDExchange Plaza, Bandra Kurla Complex,Bandra (E),Mumbai – 400051

Re.: Press Release

Dear Sir / Madam,

Please find enclosed a Press Release dated May 8, 2020 titled “Zydus Cadila Launches Enzalutamide, making Prostate Cancer therapy highly affordable”.

The contents of the Press Release give full details.

Please bring the aforesaid news to the notice of the members of the exchange and investors’ at large.

Thanking you,

Yours faithfully,For, CADILA HEALTHCARE LIMITED

DHAVAL N. SONICOMPANY SECRETARY

Encl.: As above

Regd. Office : ‘Zydus Corporate Park’, Scheme No. 63, Survey No. 536, Khoraj (Gandhinagar), Nr. Vaishnodevi Circle, S. G. Highway, Ahmedabad 382 481, India. Phone : +91-79-71800000, +91-79-48040000 www.zyduscadila.com CIN : L24230GJ1995PLC025878

Page 2: Code: CADILAHC NATIONAL STOCK EXCHANGE OF INDIA … · highly effective drug for the treatment of Prostate Cancer, under the brand name ‘Obnyx’ in India. In a step that can significantly

Zydus Cadila Launches Enzalutamide, making Prostate Cancer therapy highly affordable

• The therapy priced at nearly two-thirds the cost of the currently available products in the market

• Developed in-house, the drug offers bio-availability advantages in a soft gel capsule, dif-ferent from the hard gelatin capsules available in India

Ahmedabad, May 08, 2020

Zydus Cadila, a global innovation driven healthcare company, announced that it is launching Enzalutamide, a highly effective drug for the treatment of Prostate Cancer, under the brand name ‘Obnyx’ in India. In a step that can significantly reduce treatment cost by almost 70%, the drug is priced at Rs 5995 (weekly therapy) reducing the monthly treatment cost to less than Rs. 27000. The current MRP of Enzalutamide drug ranges from Rs. 70000 to Rs 80000 for a monthly therapy and can be a huge financial burden for the elderly patients as they need to continue the therapy for a long period of time. This price reduction will benefit many prostate cancer patients to adhere to the treatment.

One of the important aspects of prostate cancer treatment is reducing the effect of androgens (a male reproductive hormone) on prostate gland. Many patients require Androgen Receptor Targeted Therapies like Enzalutamide which works by blocking the effects of androgen to stop the growth and spread of prostate cancer cells. More importantly, it is a preferred option in patients with significant liver, heart and kidney diseases which is very common in the elderly men. Enzalutamide has an advantage of being taken through oral route. Zydus’ Obnyx scores over other formulations in the market as it is a soft gel capsule filled with liquid, similar to the innovator drug. This has been specially developed through in-house efforts. The other formulations available in the market are hard gelatin capsules.

Prostate cancer is one of the leading cancer in males in India and the risk increases with age. About 1 out of 9 men have risk of developing prostate cancer in lifetime. The incidence is nearly 60% in men over the age of 65 years. Other risk factors such as obesity, family history and improper diet have been identified as the main contributing factors towards an increased incidence of prostate cancer.

About Zydus Zydus Cadila is an innovative, global pharmaceutical company that discovers, develops, manufactures and markets a broad range of healthcare therapies, including small molecule drugs, biologic therapeutics and vaccines. The group has a significant presence in oncology therapy and offers a comprehensive basket of cytotoxic, supportive & targeted drugs including in-house manufactured monoclonal antibodies like Vivitra (Trastuzumab) and Bryxta (Bevacizumab). The group employs nearly 25,000 people worldwide, including 1,400 scientists engaged in R & D, and is dedicated to creating healthier communities globally. www.zyduscadila.com

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Press Release Press Release Press Release Press Release Press Release Press Release Press Release Press Re²lease

Cadila Healthcare LimitedRegd. Office : ‘Zydus Corporate Park’, Scheme No. 63, Survey No. 536, Khoraj (Gandhinagar), Nr. Vaishnodevi Circle, S. G. Highway, Ahmedabad 382 481, India. Phone : +91-079-71800000, +91-079-48040000 www.zyduscadila.com CIN : L24230GJ1995PLC025878

For further information please contact : The Corporate Communications Department