collasil · 2020. 12. 20. · monomethylsilanetriol (mmst) forms have the optimal bioavailability1....
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Food Nutrition Pharma
www.iontec-europe.com
These statements have not been evaluated by the Food and Drug Administration.This product is not intended to diagnose, treat, cure or prevent any disease.
Beauty, Bone & Joint
COLLASIL®The highest bioavailable
soluble silicon
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Blood
Der
mis
Epid
erm
is
SKIN
Inte
stin
al w
all
Hydrogen bonds between silicon and
collagen**
Si SiAA
AA AA
A patented stabilization technology
In Nature, di!erent chemical forms of silicon exist, which dictate its biological properties:
mineral form (insoluble): quartz, emerald, etc. active form (water soluble): orthosilicic acid and monomethylsilanetriol
Only water soluble silicon can be assimilated by the body and is biologically active. However, in high concentration, it polymerizes, becoming less instable and bioavailable.
In the body, silicon is found in conjunctive tissues like bone, cartilage, skin, vessels, etc. with a concentration that decreases with aging.
Silicon, the 2nd most abundant element on Earth
STABILIZATION
Technology
PATENTED
1Stabilization
of the silicon with a peptidic matrix composed of hydrolyzed fish collagen
Resistance Elasticity
Better intestinal absorption of amino acids and the released silicon
in the blood flow
Skin architecture Creation of biological bonds that reinforce the
skin integrity Stimulation of collagen production
No silicon polymerization
2 3
Complex : Si + matrix*
*Schematic representation of the complex** Schematic representation of the hydrogen bonds in the dermis between silicon and skin collagen
SiAA
AA AASi
Stomach
COLLASIL®OSA
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A clinically proven bioavailability
Quantity of silicon excreted in the urines in 24h after administrating the product
Silicon presents di! erent absorption profi les, depending on its organic form.
A clinical trial performed on 32 volunteers aged 19-40 years showed that the orthosilicic acid (OSA) and monomethylsilanetriol (MMST) forms have the optimal bioavailability1.
The chemistry of these forms explains this result. OSA and MMST are not only organic but also monomeric, while the other forms show varying degrees of polymerization.
Colloidal silica
Magnesium trisilicate
Orthosilicic acid (OSA)
Choline-stabilized OSA
Monomethylsilanetriol
60
40
20
0
%
1. Lassus, Journal of International Medical Research July-August 1993 vol. 21 no. 4 209-215 - 2. Barel, Arch Dermatol Res (2005) 297: 147–153 – 3. Bombonatti, AAD summer meeting, 2011 -4. Bone and Mineral Res., vol. 19, (2004), pp. 297-307 – 5. Ex vivo study on chondrocytes (1996) – 6. In vivo study on dogs after resection of the anterior cruciate ligament of the knee (1997)
COLLASIL® health benefi ts
Hair
Nails
Skin COLLASIL® OSA
COLLASIL® MS HCALGOSIL®
COLLASIL® OSAALGOSIL®
COLLASIL® OSAALGOSIL®
COLLASIL® OSAOSTEOSIL®
Wrinkle reduction1................-36%Skin elasticity2......................+19%Skin resistance2...................+58%
Anti-hair loss3......................+45%Growth3.................................+77%Brightness3..........................+86%Hair resistance1.....................+41%
Nail resistance1....................+48%
Positive connection between a silicon-rich diet and a high bone mineral density4
Enzymatic activity inhibition of stromelysin and collagenase implied in cartilage degradation5
Osteophytosis reduction6
Bone & Joint
Anti-agingArchitecture
Firmness
StrengthGrowth
Brightness
StrengthThickness
Osteoarticular systemMobility
Main benefi tsTissues Products Results of clinical studies
1. Sripanyakorn S. et al., The comparative absorption of silicon from di! erent foods and food supplements, Br J Nutr. 2009 Sep; 102(6): 825–834.
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WHY CHOOSE IONTEC SILICON ?
High bioavailability
Multiple proven beauty benefi ts
www.iontec-europe.com
These statements have not been evaluated by the Food and Drug Administration.This product is not intended to diagnose, treat, cure or prevent any disease.
Commercial Name
COLLASIL®
OSACOLLASIL®
MS HCALGOSIL® OSTEOSIL®
Orthosilic acid
Monomethyl-silanetriol
Monomethyl-silanetriol
Monoalkylsila-netriol
100 to 600 mg/day
100 to 600 mg/day
100 to 600 mg/day
15 to 20 ml/day
Marinecollagenpeptide
Marinecollagenpeptide
Mannuronicacid
PhosphorusAssociation of phosphorus (bone building block) and silicon to bring silicon closer to the cartilage
Tablets, coated tablets, capsules and shots
Stabilizationmatrix
Active compound form
Recommendeddosage
Applications
Technical dataTHE
HIGHESTBIOAVAILABLE
of soluble silicon
SO URCE