colorectal surgery in national effort to reduce surgical ... newsletter 2… · dr. sexton designs...

C.P.H.Q., and Donise Musheno, R.N., M.S., said the site visit was a great opportu-nity to meet the team members at Vanderbilt and officially kick off the Colorectal SSI project.

On the first day of the site visit, the

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Innovations in Surgery2nd Quarter 2012

In This Issue...

Pg. 2

Dr. Sexton Designs $5 Vascular Simulator

Dr. Terhune wins top resident teaching award two years running

Dr. Miller Appointed Chief of Trauma and Surgical Critical Care


Pg. 3

Pg. 4

Davis Awarded McCleery Master Teacher Award

Colorectal Surgery in National Effort to Reduce Surgical Site Infections

Alan J. Herline, M.D.

The Section of Surgical Sciences in April bestowed its highest teach-ing award to Rodney Davis, M.D., professor of Urologic Surgery.

The Robert S. McCleery Master Teacher Award was established in 2008 to recognize outstanding full-time teachers of surgical residents at Vanderbilt University Medical Center.

“Rodney Davis’ passionate com-mitment to duty is evident in his teaching style. He teaches by exam-ple, interest in others, and a com-mand of surgical skills,” said Joseph A. Smith, M.D., chair of Urologic Surgery.

Each academic year, surgical residents nominate the faculty member they believe best exemplifies the principles of Dr. Mc-Cleery, who was revered for outstanding bedside teaching and meticulous operative technique.

In introducing this year’s award recipient, senior resident Kelly Stratton, M.D., joined his fellow residents in giving Dr. Davis a

Rodney Davis, M.D., (center) with senior resident Kelly Strat-ton, M.D., (left), and R. Daniel Beauchamp, M.D., chairman of Surgical Sciences (right)

standing ovation.

“Dr. Davis helps us find the confi-dence we need to care for our patients, both in the operating room and at the bedside,” said Stratton. “His heartfelt conversations about life and why we all became doctors in the first place is what empowers us to be the best we can,” he said.

One of only four medical facilities in the United States, Vanderbilt is working with the American College of Surgeons and the Centers for Disease Control and Prevention to reduce infections fol-lowing colorectal surgery – one of the most commonly performed procedures in hospitals today.

Surgical Site Infections (SSIs) can cause patient injury, mortality, pro-longed hospitalization and increased healthcare costs. To address these serious healthcare concerns, the Joint Commission Center for Transforming

Healthcare established a program to as-sess what hospitals are doing to reduce such infections and then share these best practices.

As part of this national pilot pro-gram, the Joint Commission recently conducted a two-day site visit at Vanderbilt to review all patient process-es from the time a patient comes to the clinic to the time he is discharged.

Joint Commission Black Belt project leads for Robust Process Improvement Siew Lee Grand-Clement, R.N., M.S.N.,

Innovations in Surgery is produced quarterly by the Section of Surgical Sciences.

R.Daniel Beauchamp, MD, Chairman and the Foshee Distinguished Professor of Surgery

Send story ideas or suggestions [email protected], (615) 322-4625.

Mimi Eckhard, director, media servicesEmily Goad, media services specialist www.mc.vanderbilt.edu/surgicalsciences

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Vanderbilt Resident Designs $5 Vascular Simulator

Because arteries are found at various depths throughout the body, vascular surgery has been described as sewing in a hole. So, how do you train surgical residents this skill before they enter the operating room?

It’s a common question asked at medical centers across the country. So, Vascular Surgery Program Director Jeffery B. Dattilo, M.D., and Profes-sor Colleen Brophy, M.D., challenged General Surgery Resi-dent Kevin W. Sexton, M.D., to come up with an answer.

In one weekend and a trip to the hardware store, he and his wife Deb, who worked in simulation centers while in nursing school, designed the $5 vas-cular simulator.

A far cry from the cost of actual simulators that can run into the thou-sands, Sexton’s inexpensive simulator is now enabling residents to easily and effectively practice intricate vascular surgical techniques and vessel repair.

Using nothing more than cop-per tubing, plastic bird guards often used to block dryer vents, a drain, and some miscellaneous items such as wood screws and two-by-fours, Sexton produced 18 vascular simulators for a residency workshop.

In the first two-hour workshop, 24 first-year surgery residents practiced multiple vascular techniques at various anatomically challenging positions.

The residents were then asked for their feedback on the simulator. The results were overwhelmingly positive.

All of the respondents indicated they would like to have the simulator for personal use; 67 percent were willing to pay for the device at an average price of $25, and 83 percent reported the simu-lator improved their confidence that

they could one day perform such techniques on actual patients.

“It’s not uncommon to come up with non-tradition-al solutions to medical train-ing. Residents do this all the time. I practiced vascular anastomoses in a coffee can because that is what my chief resident said worked,” said Sexton. “What makes our design useful is we can share it with other residents and institutions all wanting cost-effective simulation. That’s the win,” he said.

Sexton presented his de-sign in March in San Diego at Surgery Education Week, a meeting of the Associa-tion of Program Directors in Surgery and the Associa-tion for Surgical Education. His paper, co-authored by Dattilo and Brophy, was en-titled, “Need cost effective surgical simulation? Send a resident to the hardware store.”

Surgery Education Week is designed to provide a forum for those involved in surgical education to seek new approaches and creative solutions to issues in medical education.

“Low-tech and inexpensive partial task trainers are of great value to both new learners, as well as skills champi-ons. We are surrounded here at Vander-bilt by incredibly bright residents such as Kevin Sexton and are most fortunate to also benefit from Deb’s experience and input,” said John L. Tarpley, M.D., program director of General Surgery Residency. q

Kevin W. Sexton, M.D. Some plastic dryer guards, copper tubing and surgical ingenuity were all it took to develop a simulator Vanderbilt residents are proud to call their own.

Residents can now practice the fine art of vascular surgery, which requires skill at various depths within the body.

Richard S. Miller, M.D., has been named chief of the division of Trauma and Surgical Critical Care. He was Vanderbilt’s first fellow in the Division from 1990 to 1992.

Miller has been serving as acting chief since last July, and succeeds John Mor-ris, Jr., M.D., who founded the Trauma Center at Vanderbilt in 1984 and served as division chief from 1986 to 2011.

The Vanderbilt Division of Trauma is the only Level 1 Trauma Center in middle Tennessee, providing trauma care to more than 3,000 patients each year.

“We are quite excited by this appointment,” said Naji N. Abumrad, M.D., chairman of the Depart-ment of Surgery.

“Rick has been recog-nized nationally in this area for some time now, and we are certain that he will con-tinue to build on the solid foundations established by Dr. Morris in creating the strongest academic trauma and critical care unit in the nation,” he said.

“I am honored to lead this incredibly smart, talented team of trauma profes-sionals who demonstrate every day how we all play an integral role in caring for our patients,” said Miller.

“We will continue to focus on what we do best, trauma care, as well as pro-vide ongoing research, education and resources to fully prepare each patient for what comes next on the road to recovery,” he said.

Although back surgery last September put his active lifestyle on hold tempo-rarily, Miller and his daughter Alyssa participated in a triathlon in May. “As you can imagine, life in the trauma unit can be very demanding. Spending qual-ity time with my wife and daughters is what makes me a better doctor,” he said.

Miller received his medical degree

from the Universidad C.E.T.E.C., Santo Domingo in the Dominican Republic, after completing his bachelor of arts in biology/natural sciences from the University of South Florida.

He went on to complete his residency in general surgery at Easton Hospital and Hahnemann University Hospital in Pennsylvania. He then completed his fellowship in trauma and Surgical Criti-cal Care at Vanderbilt University.

Following faculty appointments at the Greenville Hospital System and Medical

University of South Carolina, Miller was recruited back to Vanderbilt in 2002.

He is a Diplomate of the American

Board of Surgery, a frequent guest lecturer, and has authored more than 50 publica-tions, including five book chapters.

His current research focuses on the management and reconstruc-tion of complex abdominal wall hernias.

“As we welcome Dr. Miller into this important posi-tion of leadership, we also wish to recognize and thank Dr. Morris who stepped down last year as the founding division chief, having led the Division of Trauma and Surgical Critical Care for 27 years with outstanding service,” said R. Daniel Beauchamp, M.D., chairman of the Section of Surgical Sciences and the Foshee Distinguished Professor of Surgery.

Morris continues to lead LifeFlight, Emergency Preparedness and Acute Care Services. q

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Miller Appointed Chief of Trauma and Surgical Critical Care

Rick Miller, M.D.

John Morris, Jr., M.D.

Dr. Miller making family rounds in the Trauma Unit

Section Events CalendarJune 2012June 26-27The Vanderbilt Center for Benign Urologic Diseases Scientific Retreat 2012 -- Vanderbilt Student Life Center, Board of Trust Room, Nashville, TN. The Retreat will explore the urologic links between obesity and diabetes.

Jill Macoska, Ph.D., professor of the Department of Urology, University of Michi-gan Medical School Program in Biomedical Science, is this year’s invited keynote speaker. Macoska will address “Prostatic Fibrosis as Contributing Pathobiology to Lower Urinary Tract Dysfunction.”

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McCleery Award...(Continued from page 1)

Davis expressed his gratitude for the recognition, saying, “It’s truly a pleasure sharing what I’ve learned along the way with these incredibly talented residents. I joke that they must learn so they can take care of me one day, but they really will take the helm and care for us all,” he said.

Davis earned his medical degree from Tulane University School of Medicine in New Orleans, Louisiana in 1982. He then completed residencies in General Surgery and Urology from the Madi-gan Army Medical Center in Tacoma, Washington, and a fellowship in Urol-ogy from The University of Texas M.D. Anderson Cancer Center in Houston, Texas.

Davis also holds appointments in Nashville as chief of Urology at the Tennessee Valley Veterans Health Care

System and at Meharry Medical College.

A highly decorated member of the U.S. Army, Davis has served throughout the U.S., in the Persian Gulf, Germany and Iraq. He frequently travels to Af-rica, providing critically needed surgeries as part of mission work in the area.

“Dr. Davis is an outstanding teacher who is a positive role model of compas-sion and excellence in patient care for students, residents and for his faculty colleagues. We are grateful to the late Dr. Eustace Winn, Jr. and to his family who generously endowed and support this annual award,” said R. Daniel Beau-

champ, M.D., the Foshee Distinguished Professor of Surgery and Chairman of the Section of Surgical Sciences.

The late Eustace H. Winn, Jr., M.D., was a Vanderbilt benefactor and surgi-cal resident who trained under the late Robert S. McCleery, M.D. q

Urologic Surgery residents give Davis a standing ovation.

Surgical Residents and Attendee Presented with Top Awards

Terhune Again Wins Top Resident Teaching Award

For the second year in a row, Kyla Terhune, M.D., was honored with the J. W. Hillman House Officer Teaching Award, the highest House Staff Teach-ing award.

One of only five resident teaching awards bestowed for excellence in teaching at Vanderbilt, the Hillman Award is presented to the resident deemed the best teacher and role model, as selected by fourth-year medical students.

From a pool of nearly 900 residents and fellows, Terhune received the esteemed Hillman Award, though her tenure as chief resident concluded in 2011.

“This is quite a statement on Dr. Terhune’s ability to teach, mentor and perform by example,” said John L. Tar-pley, program director of the General Surgery Residency program.

When asked why the residents decided to yet again nominate Dr. Terhune, though she is now a faculty member and associate program direc-tor in General Surgery, the answer was simple. “She sets the bar, whether for one year or four.”

Hillman joined the Vanderbilt fac-ulty in 1952 and was instrumental in Vanderbilt establishing the department of Orthopaedics and Rehabilitation, which he chaired from 1962 through 1970. He was well known for his work with crippled children.

One year following Hillman’s death at the age of 49, the Hillman Award was established in 1971. John Sergent, M.D., program director of Medicine, received the first Hillman Award. q

Kyla Terhune, M.D.

Resident Awards Presented at Grand Rounds

The Section of Surgical Sciences on June 8 paid special tribute to its top residents with a special Resident Awards presentation at Surgical Grand Rounds.

Christina Bailey, M.D., M.S.C.I., received The Harwell Wilson Award -- given annually to the chief resident who epitomizes the ideals of dedication to patient care, research and teaching.

J. Joshua Smith, M.D., Ph.D. received The Alfred Blalock Surgical Resi-dent Award -- established in 1988 to honor the resident whose published laboratory or clinical research marks an outstanding contribution to medical research.

Felicitas Koller, M.D., received The Joseph W. & Bonnie J. Graves Award in Surgery -- established in 1995 to pay tribute to the resident who demon-


better understand why infections occur and how they can be reduced.

“Our goal has always been to reduce infections to the lowest level pos-sible. We have attacked this problem by assuring consistency in all our processes and reviewing our results, and are now excited to have input from the Joint Com-mission,” said Alan J. Herline, M.D., director of the Colon and Rectal Surgery Pro-gram and associate professor of Colon and Rectal Surgery. “Our mission is to make sure each patient has the best opportunity to have an infection-free operation,” he said.

Chaired by Professor of Surgery and Anesthesiology Addison K. May, M.D., and co-chaired by Administrative Direc-tor of Nursing David A. Wyatt, M.D., the SSI Collaborative Committee has implemented a variety of best prac-tices, including standardization of OR preparations, as well as a new electronic surgical checklist.

The Committee works closely with Herline and Cindy Kildgore, OR direc-tor at Medical Center East, where most

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Reducing Infections...(Continued from page 1)

R. Daniel Beauchamp, M.D., project sponsor of the effort to reduce surgical site infections follow colorectal surgery, attends a briefing on the Joint Commission site visit.

Joint Commission project leads “walked the process” by observing two patients from admission to pre-operative prepa-ration, the actual procedures performed in the operating room, and finally to the patient care unit. They also visited the Colorectal Surgery Clinic, observing the process involved in an urgent/emergent in-patient case.

The focus of the second day was an intensive review of colorectal patient care data, including flow process maps of patient care. This analysis, which included Emergency General Surgery staff, as well as Colorectal Surgery frontline nurses, will ultimately create a plan that can then be shared in hospitals throughout the U.S.

“We have been actively working on reducing these kinds of infections for some time, so it was an honor to be asked by the Joint Commission to demonstrate our processes,” said Susie Leming-Lee, associate director of Peri-operative Services. “Obviously, there’s no silver bullet, so this program will enable us to find missing gaps, as well as share some of our best practices with other institutions,” she said.

Even before the Joint Commission pi-lot program was launched, the Vander-bilt Surgical Site Infection Collaborative Committee was established in 2009 to

of the colorectal surgeries are per-formed.

“We welcome this opportunity to work collaboratively with the Joint Commission to reduce colorectal surgi-cal site infections. Our Colorectal Sur-gery and Perioperative Enterprise team has already made tremendous progress in this area, so we have the opportunity to both learn lessons from other cen-ters, as well as share important learnings from Vanderbilt,” said R. Daniel Beau-champ, M.D., the Foshee Distinguished Professor of Surgery and Chairman of the Section of Surgical Sciences. Beau-champ serves as the project sponsor of the Joint Commission pilot program at Vanderbilt. q

Hayward Selected for NIH Study Section

The National Institutes of Health (NIH) has invited Simon Hayward, Ph.D., assistant professor of Urologic Surgery, to serve as a member of the Urologic and Genitourinary Physiology and Pathology Study Section for the Center for Scientific Review.

During his four-year term, which ends June 30, 2016, Hayward will review grant applications submitted to the NIH, make recommendations on grants, and survey the status of research in the particular field of urologic science.

Members are selected on the basis of their demonstrated competence and achievement in their scientific discipline as evidenced by the quality of research accomplishments, publications in scientific journals and other significant activities, achievements and honors.

Hayward is also the primary inves-tigator and director of the Vanderbilt Center for Benign Urologic Diseases.

Millions of Americans over the age of 50 suffer from a range of prostate

and bladder ail-ments, as well as lower urinary tract symptoms. Hay-ward hopes that research in this area will lay the groundwork for appropriate treat-ment options for the broader disease syndrome. q

Simon Hayward, Ph.D.

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New to the SectionThe Section of Surgical Sciences welcomes its newest additions.

Walter Merrill, M.D.., professor, Cardiac Surgery, and chief of staff, Vanderbilt Univer-sity Hospital

Elizabeth Dovec, M.D., instructor, General Surgery

Khubaib Mapara, M.D., assistant professor, General Surgery

Aqeela Afzal, Ph.D., M.B.A., research assistant professor, Neuro-logical Surgery

Lola Chambless, M.D., assistant professor, Neuro-logical Surgery

Mark Cobb, M.D., M.S., assistant professor, Neuro-logical Surgery

Edward Perry, III, M.D., instruc-tor, Neurological Surgery

J Mocco, M.D., associate profes-sor, Neurological Surgery

Kent “Kye” Higdon, M.D., assistant professor, Plastic Surgery

Steven Brooks, M.D., instructor, Trauma and Surgi-cal Critical Care

Neeta Chaudhary, M.D., instructor, Trauma and Surgi-cal Critical Care

Bradley Dennis, M.D., instructor, Trauma and Surgi-cal Critical Care

Shannon Eastham, M.D., instructor, Trauma and Surgi-cal Critical Care

Jeffrey C. Bassett, M.D., instructor, Urologic Surgery

Aaron Benson, M.D., instructor, Urologic Surgery

David James Osborn, M.D., instructor, Urologic Surgery

Chad Ryan Ritch, M.D., instructor, Urologic Surgery

Gary Solomon, Ph.D., associate professor, Neu-rological Surgery and Psychiatry

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Section Publications

The following publications appeared through the second half of 2011. Congratulations to the Section faculty on their ongoing research at Vanderbilt University Medical Center.


Cardiac SurgeryJaik NP, Umakanthan R, Leacche M, Solenkova N, Balaguer JM, Hoff SJ, Ball SK, Zhao DX, Byrne JG. Current status of hybrid coronary revascularization. Expert Rev. Cardiovasc Ther. 2011 Oct;9(10):1331-1337.

Leacche M, Zhao DX, Umakanthan R, Byrne JG: Hybrid coronary revascularization. In: R.O. Bonow, D.L. Mann, D.P. Zipes, P. Libby, eds. Braunwald’s Heart Disease, 9th ed (edi-tion). Philadelphia, Pennsylvania: Elsevier. www.expertcon-sult.com. 2011 Aug 25.

Petracek MR, Leacche M, Solenkova N, Umakanthan R, Ahmad RM, Ball SK, Hoff SJ, Absi TS, Balaguer JM, By-rne JG. Minimally invasive mitral valve surgery expands the surgical options for high-risks patients. Ann Surg. 2011 Oct;254(4):606-11.

Umakanthan R, Leacche M, Zhao DX, Gallion AH, Mishra PC, Byrne JG. Hybrid Options for Treating Cardiac Disease. Seminars in Thor and Cardiovasc Surg. 2011 Winter;23(4):274-80.

Pediatric Cardiac SurgeryBichell DP. Invited commentary: Long-term myocardial scarring after operation for anomalous left coronary artery from the pulmonary artery. Ann Thorac Surg. 2011;92(5):1765-6.

General SurgeryBellcross CA, Bedrosia S, Daniels E, Duquette D, Hampel H, Jasperson K, Joseph DA, Kaye C, Lubin I, Meyer LJ, Reyes M, Scheuner MT, Schully SD, Senter L, St. Pierre J, Stewart LS, Westman J, Wise PE, Yang VW, Khoury MJ. Implement-ing population-based genetic screening and cascade testing for Lynch syndrome: summary of a public health/clinical collaborative meeting. Genet Med. 2012 Jan;14(1):152-62. EPub 2011 Oct 27.

McCauley J, Haaz S, Tarpley MJ, Koenig HG, Barlett SJ. A randomized controlled trial to assess effectiveness of a spiritually-based intervention to help chronically ill adults. Int J Psychiatry Med. 41(1):91-105, 2011.

Muldoon RL, Hartmann’s Reversal-Open Technique. Chapter in Fleshman JW, Wexner S, Eds. Master Techniques in Colon and Rectal Surgery. Lippincott Williams & Wilkins/Wolters Kluwer Health, Philadelphia, PA, 2011.

Oke AJ, Olaolorun DA, Meier DE, Tarpley J. Gram stain microbiological pattern of upper extremities suppuration at Baptist Medical Centre, Ogbomoso Nigeria: a fifteen month

review. Afr J Med Med Sci. Jun;40(2):159-62. 2011.

Shelton J, Kummerow K, Phillips S, Griffin M, Holzman MD, Nealon W, Pinson CW, Poulose BK. An urban-rural blight? Choledocholithiasis presentation and treatment. J Surg Res. 2012 Apr;173(2):193-7. Epub 2011 Jun 15.

Tamboli RA, Hajri T, Jiang A, Marks-Shulman PA, Williams DB, Clements RH, Melvin W, Bowen BP, Shyr Y, Abumrad NN, Flynn CR. Reduction in inflammatory gene expression in skeletal muscle from Roux-en-Y gastric bypass patients randomized to omentectomy. PLoS One. 2011;6(12):e28577. Epub 2011 Dec 16.

Weissman SM, Burt R, Church J, Erdman S, Hampel H, Holter S, Jasperson K, Kalady MF, Haidle JL, Lynch HT, Pa-laniappan S, Wise PE, Senter L. Identification of individuals at risk for Lynch syndrome using targeted evaluations and ge-netic testing: National Society of Genetic Counselors and the Collaborative Group of the Americas on Inherited Colorectal Cancer Joint Practice Guideline. J Genet Couns. 2011 Dec 14.

Wise PE. Chapter 36, Polyps. Chapter in Beck D, Senagore A, Roberts P, Wexner S, SaclaridesT, Stamos M, Eds. ASCRS Textbook of Colon and Rectal Surgery, 2nd edition. Springer, New York, NY; 2011.

Wise PE. Total Proctocolectomy with Ileostomy: Hand Assisted. Chapter in Fleshman JW, Wexner S, Eds. Master Techniques in Colon and Rectal Surgery. Lippincott Williams & Wilkins/Wolters Kluwer Health, Philadelphia, PA, 2011.

Hepatobiliary Surgery & Liver TransplantationZaydfudim V, Feurer ID, Landmann MP, Moore DE, Wright JK, Pinson CW. Reduction in corticosteroids is associated with better health-related quality of life after liver transplan-tation. Journal of the American College of Surgeons. 214:164-73, EPub 2011 Dec 3.

Kyu LI, Hun J, Kyung PK, Young CD, Suk LY, Youn S, Gorden DL, Jun-Gi K, Teak O. Is conservative treatment with antibiotics the correct strategy for treatment of right co-lonic diverticulitis? A prospective study. J Korean Soc Coloproctol. 2011 Aug; 27(4):188-93.

Gorden DL, Ivonova PT, Myers DS, McIntyre JO, Van Saun MN, Wright JK, Matrisian LM, Brown HA. Increased Diacyl-glycerols Characterize Hepatic Lipid Changes in Progression of Human Nonalcoholic Fatty Liver Disease; Comparison to a Murine Model. 2011 Aug; 6 (8) PLoS ONE.

Renal & Pancreas TransplantationSam WJ, Chamberlain CE, Lee SJ, Goldstein JA, Hale DA,

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Publications...(Continued from page 7)


Mannon RB, Kirk AD, Yi Hon Y. Associations of ABCB1 3435C>T and IL-10-1082G>A polymorphisms with long-term sirolimus dose requirements in renal transplant patients. Transplantation. 2011 Dec 27;92(12):1342-7.

Surgical Oncology & Endocrine SurgeryBroome JT, Solórzano CC. The impact of atypia/follicular lesion of undetermined significance on the rate of malignancy in thyroid fine-needle aspiration: evaluation of the Bethesda System for Reporting Thyroid Cytopathology. Surgery. 2011 Dec;150(6):1234-41.

Carneiro-Pla DM, Solorzano CC. Intraoperative Parathyroid Hormone Monitoring. In: UpToDate, Basow, DS (Ed), UpTo-Date, Waltham, MA, 2011.

Freeman TJ, Smith JJ, Chen X, Washington MK, Roland JT, Means AL, Eschrich SA, Yeatman TJ, Deane NG, Beau-champ, RD. Smad 4-Mediated Signaling Inhibits Intestinal Neoplasia by in habiting Expression of β-Catenin. Gastroenter-ology 2012; 142:562-571. (2011 Nov 21 ePub ahead of print)

Goldfarb M, Gondek S, Solórzano C, Lew JI. Surgeon-per-formed ultrasound can predict benignity in thyroid nodules. Surgery. 2011 Sep;150(3):436-41.

Jabiev AA, Lew JI, Garb JL, Sanchez Y, Solorzano CC. Pri-mary hyperparathyroidism in the underinsured: A study of 493 patients. Surgery 151: 471-8, Epub 2011 Oct 13.

Keller MD, Vargis E, de Matos Granja N, Wilson RH, Mycek MA, Kelley MC, Mahadevan-Jansen A. Develop-ment of a spatially offset Raman spectroscopy probe for breast tumor surgical margin evaluation. J Biomed Opt. 2011 Jul;16(7):077006.

Li X, Welch EB, Arlinghaus LR, Chakravarthy AB, Xu L, Farley J, Loveless ME, Mayer IA, Kelley MC, Meszoely IM, Means-Powell JA, Abramson VG, Grau AM, Gore JC, Yan-keelov TE. A novel AIF tracking method and comparison of DCE-MRI parameters using individual and population-based AIFs in human breast cancer. Phys Med Biol. 2011 Sep 7;56(17):5753-69. Epub 2011 Aug 12.

Li X, Welch EB, Chakravarthy AB, Xu L, Arlinghaus LR, Farley J, Mayer IA, Kelley MC, Meszoely IM, Means-Powell J, Abramson VG, Grau AM, Gore JC, Yankeelov TE. Statistical comparison of dynamic contrast-enhanced MRI pharmaco-kinetic models in human breast cancer. Magn Reson Med. 2011 Nov 29.

Poulikakos PI, Persaud Y, Janakiraman M, Kong X, Ng C, Moriceau G, Shi H, Atefi M, Titz B, Gabay MT, Salton M, Dahlman KB, Tadi M, Wargo JA, Flaherty KT, Kelley MC,

Misteli T, Chapman PB, Sosman JA, Graeber TG, Ribas A, Lo RS, Rosen N, Solit DB. RAF inhibitor resistance is medi-ated by dimerization of aberrantly spliced BRAF (V600E). Nature. 2011 Nov 23;480(7377):387-90.

Trauma and Surgical Critical CareBonatti HJ, Colon N, Ott M, Morris JA, Miller RS, Riordan WP, May AK. Trimethoprim-Associated Hyperkalemia in a Young Trauma Victim. Surgical Infections. 2011; 12:419-420.

Campion TR, Jr, Waitman LR, Lorenzi NM, May AK, Gadd CS. Barriers and Facilitators to the Use of Computer-based Intensive Insulin Therapy. International Journal of Medical Infor-matics. 2011; 80:863-871.

Diaz, JJ, Norris PR, Gunter OL, Collier BR, Riordan WR, Morris JA Jr. Does Regionalization of Acute Care Surgery Decrease Mortality? J Trauma 71(2):442-6. 2011 Aug.

Dortch MJ, Fleming SB, Kauffmann RM, Dossett LA, Talbot TR, May AK. Infection Reduction Strategies including Anti-biotic Stewardship Protocols in Surgical &Trauma Intensive Care Units Are Associated with Reduced Resistant Gram-Negative Healthcare-Associated Infections. Surgical Infections. 2011; 12:15-25.

Heffernan D, Dossett LA, Lightfoot M, Sawyer RG, May AK. Gender and ARDS in critically injured adults: A pro-spective study. Journal of Trauma. 2011; 71:878-885.

Kauffmann RM, Hayes RM, Jenkins JM, Norris PR, Diaz JJ, Jr., May AK, Collier BR. Provision of balanced nutrition protects against hypoglycemcia in the critically ill surgical patient. JPEN Journal of Parenteral and Enteral Nutrition. 2011; 35:686-694.

May AK. Skin and soft tissue infections: the new surgical in-fection society guidelines. Surgical Infections. 2011; 12:179-184.

May AK, Kauffman RM, Collier BR. The Place for Glyce-mic Control in the Surgical Patient. Surgical Infections. 2011; 12:405-418.

Talbot TR, May AK, Obremskey WT, Wright PW, Daniels TL. Intraoperative Patient-to-Healthcare Worker Transmis-sion of Invasive Group A Streptococcal Infection. Infection Control and Hospital Epidemiology. 2011; 32:924-926.

Vascular SurgeryEagle S, Brophy CM, Komalavilas P, Hocking K, Putumbaka G, Osgood M, Sexton K, Leacche M, Cheung-Flynn J. Surgi-cal skin markers impair human saphenous vein graft smooth muscle and endothelial function. Am Surg. 2011 Jul;77(7):922-8.

Garcia CB, Shaffer CM, Alfaro MP, Smith AL, Sun J, Zhao Z, Young PP, Vansaun MN, Eid JE. Reprogramming of mesenchymal stem cells by the synovial sarcoma-associated oncogene SYT-SSX2. Oncogene. 2011 Sep 26. doi: 10.1038/onc.2011.418.

Guney MA, Petersen CP, Boustani A, Duncan MR, Gunas-ekaran U, Menon R, Warfiel, C, Grotendorst GR, Means AL, Economides AN, Gannon M. 2011. Connective tissue growth factor acts within both endothelial cells and beta cells to pro-mote proliferation of developing beta cells. PNAS 108:15242-15247.

Hajri T, Tao H, Wattacheril J, Marks-Shulman P, Abumrad NN. Regulation of adiponectin production by insulin: inter-actions with tumor necrosis factor-α and interleukin-6. Am J Physiol Endocrinol Metab. 2011 Feb;2(300):E350-60.

Halder SK, Cho Y-J, Datta A, Anumanthan G, Ham A-JL, Carbone DP, Datta PK. Elucidating the mechanism of regula-tion of TGF-ß type II receptor expression in human lung cancer cell lines, Neoplasia, 13(10): 912-922, 2011.

Kashikar N, Zhang W, Massion P, Gonjalez A, Datta PK. Role of STRAP in regulating GSK3ß function and Notch3 stabili-zation. Cell Cycle, 10(10): 1639-1654, 2011.

Le Bras GF, Richards N, Allison G, McCowan KM, Andl CD. CD44 upregulation in E-cadherin negative esophageal cancer results in cell invasion. PLoS ONE 2011; 6(11): e27063.

Lim J, Jang G, Kang S, Lee G, Nga DT, Phuong DT, Kim H, El-Rifai W, Ruley HE, Jo D. Cell permeable NM23 blocks the maintenance and progression of established pulmonary metastasis. Cancer Research, 71(23):7216-25, 2011

Mason TA, Kolobova E, Liu J, Roland JT, Chiang C, GOLD-ENRING JR. (2011) Darinaparsin is a multivalent chemother-apeutic which induces incomplete stress response with disrup-tion of microtubules and Shh signaling. Plos One, 6:e27699

Nam KT, O’Neal RL, Coffey RJ, Finke PE, Barker N, GOLDENRING JR. (2011) Spasmolytic polypeptide-express-ing metaplasia (SPEM) in the gastric oxyntic mucosa does not arise from Lgr5-expressing cells. GUT. 2011 Dec 23.

Peng D, Lu T-L, Jiang A, Washington MK, Moskaluk CA, Schneider-Stock R, El-Rifai W. Location-specific Epigenetic Regulation of the Metallothionein 3 Gene in Esophageal Ad-enocarcinomas. PlosOne, 6(7):e22009, 2011.

Peng D, Belkhiri A, Hu TL, Chaturvedi R, Asim M, Wilson KT, Zaika A, El-Rifai W. Glutathione Peroxidase 7 Protects

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Clair DG, Hopkins LN, Mehta M, et al. EMPiRE Clinical Study Investigators. Neuroprotection during carotid artery stenting using the GORE flow reversal system: 30-day out-comes in the EMPiRE clinical study. Catheter Cardiovasc Interv 2011; Feb 15; 77(3):429-9.

Powell RJ, Comerota AJ, Berceli SA, Guzman R, Henry TD, Tzeng E, Velazquez O, Marston WA, Bartel RL, Long-core A, Stern T, Watling S. Interim analysis results from the RESTORE-CLI, a randomized, double-blind multicenter phase II trial comparing expanded autologous bone marrow-derived tissue repair cells and placebo in patients with critical limb ischemia. J Vasc Surg. 2011 Oct;54(4):1032-41.

Woo KV, Qu X, Babaev VR, Linton MF, Guzman RJ, Fazio S, Baldwin HS. Tie1 attentuation reduces murine atheroscle-rosis in a dose-dependent and sheath stress-specific manner. J Clin Invest 2011 Apr 1; 121(4):1624-35.

Burn SurgeryGuy, J.S. “Basic airway skills” PHTLS Podcast. 2011 Nov 25. http://phtlspodcast.com/2011/11/25/basic-airway-skills.aspx.

Surgical ResearchAbumrad NN, Rathmacher JA. Exercise-Induced Muscle Damage is Not Attenuated by Maximuscle β-Hydroxy-β-Methylbutyrate-1000™ Supplementation. J Strength Cond Res. 2011 May 6.

Dhawan P, Ahmad R, Srivastava AS, Singh AB. Cancer stem cells and colorectal cancer: an overview. Curr Top Med Chem. 2011;11(13):1592-8. Review.

Dhawan P, Ahmad R, Chaturvedi R, Smith JJ, Midha R, Mittal MK, Krishnan M, Chen X, Eschrich S, Yeatman TJ, Harris RC, Washington MK, Wilson KT, Beauchamp RD, Singh AB. Claudin-2 expression increases tumorigenicity of colon cancer cells; role of epidermal growth factor receptor activation. Oncogene. 2011 Jul 21;30(29):3234-47. doi: 10.1038/onc.2011.43.

Dunn JP, Abumrad NN, Breitman I, Marks-Shulman PA, Flynn CR, Jabbour K, Feurer ID, Tamboli RA. Hepatic and peripheral insulin sensitivity and diabetes remission at 1 month after Roux-en-Y gastric bypass surgery in pa-tients randomized to omentectomy. Diabetes Care. 2012 Jan;35(1):137-42. Epub 2011 Oct 31.

Fuller JC Jr, Baier S, Flakoll P, Nissen SL, Abumrad NN, Rathmacher JA. Vitamin D status affects strength gains in older adults supplemented with a combination of β-hydroxy-β-methylbutyrate, arginine, and lysine: a cohort study. JPEN J Parenter Enteral Nutr. 2011 Nov;35(6):757-62. Epub 2011 Aug 1. (Continued on page 10)

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Against Oxidative DNA Damage in Oesophageal Cells. GUT, 2011 Dec 9.

Ray KC, Bell KM, Yan J, Gu G, Chung CH, Washington MK, Means AL. 2011. Epithelial tissues have varying degrees of susceptibility to KrasG12D-initiated tumorigenesis in a mouse model. PlosOne 6: e16786.

Reiner J, Ye F, Kashikar N, Datta, PK. STRAP regulates cel-lular proliferation and ubiquitin-mediated proteolysis of the c-Jun oncogene. BBRC, 407(2): 372-377, 2011.

Singh AB, Sharma A, Smith JJ, Krishnan M, Chen X, Eschrich S, Washington MK, Yeatman TJ, Beauchamp RD, Dhawan P. Claudin-1 up-regulates the repressor ZEB-1 to inhibit E-cadherin expression in colon cancer cells. Gastroenterology. 2011 Dec;141(6):2140-53.

Tamboli RA, Hajri T, Jiang A, Marks-Shulman PA, Williams DB, Clements RH, Melvin W, Bowen BP, Shyr Y, Abumrad NN, Flynn CR. Reduction in inflammatory gene expression in skeletal muscle from Roux-en-Y gastric bypass patients randomized to omentectomy. PLoS One. 6(12):e28577. 2011 Dec 16.

Williams CS, Zhang B, Smith JJ, Jayagopal A, Barrett CW, Pino C, Russ P, Presley SH, Peng D, Rosenblatt DO, Haselton FR, Yang JL, Washington MK, Chen X, Eschrich S, Yeatman TJ, El-Rifai W, Beauchamp RD, and Chang MS. BVES regu-lates epithelial-mesenchymal phenotype and is silenced via promoter methylation in human epithelial malignancy. Journal Clinical Investigation, 121(10):4056-69, 2011

Yin DP, Gao Q, Ma LL, Yan W, Williams PE, McGuinness OP, Wasserman DH, Abumrad NN. Assessment of differ-ent bariatric surgeries in the treatment of obesity and insulin resistance in mice. Ann Surg. 2011 Jul;254(1):73-82.

Zhu S, Belkhiri A, El-Rifai W. DARPP-32-mediated EGFR protein stability leads to gefitinib resistance in gastric cancer. Gastroenterology, 141(5):1738-1748, 2011

Neurological SurgeryAdogwa O, Parker SL, Bydon A, Cheng J, McGirt MJ. Com-parative effectiveness of minimally invasive versus open transforaminal lumbar interbody fusion: 2-year assessment of narcotic use, return to work, disability, and quality of life. J Spinal Disord Tech. 2011 Dec;24(8):479-84.

Adogwa O, Parker SL, Shau DN, Mendenhall SK, Aaronson OS, Cheng JS, Devin CJ, McGirt MJ. Preoperative Zung De-pression Scale predicts outcome after revision lumbar surgery for adjacent segment disease, recurrent stenosis, and pseudar-throsis. Spine J. 2011 Sep 20.

Adogwa O, Parker SL, Shau D, Mendelhall SK, Cheng J, Aaronson O, Devin CJ, McGirt MJ. Long-term outcomes of revision fusion for lumbar pseudarthrosis: clinical article. J Neurosurg Spine. 2011 Oct;15(4):393-8.

Camalier CR, Kaas J. Functional organization of primate au-ditory pathway and interactions with pathways of reward. In: Sensation and Reward, ed. Jay A. Gottfried, pp 183-208. CRC press, Boca Raton, FL (2011).

Chaichana KL, Zaidi H, Pendleton C, McGirt MJ, Grossman R, Weingart JD, Olivi A, Quiñones-Hinojosa A, Brem H. The efficacy of carmustine wafers for older patients with glio-blastoma multiforme: prolonging survival. Neurol Res. 2011 Sep;33(7):759-64.

Chapman JR, Norvell DC, Hermsmeyer JT, Bransford RJ, DeVine J, McGirt MJ, Lee MJ. Evaluating common outcomes for measuring treatment success for chronic low back pain. Spine. 2011 Oct 1;36(21 Suppl):S54-68. Review.

Ding S, Miga MI, Simpson AL, Pheiffer TS, Thompson RC, Dawant BM, Tracking of vessels in intra-operative micro-scope video sequences for cortical displacement estimation. IEEE Transactions on Biomedical Engineering. 58(7):1985-93, 2011.

Fernandez-L A, Squatrito M, Northcott P, Awan A, Hol-land EC, Taylor MD, Nahlé Z, Kenney AM. Oncogenic YAP promotes radioresistance and genomic instability in medul-loblastoma through IGF2-mediated Akt activation. Oncogene. 2011 Aug 29.

Forbes JA, Reig AS, Smith JG, Jermakowicz W, Tomycz L, Shay SD, Sun DA, Wushensky CA, Pearson MM. Findings on preoperative brain MRI predict histopathology in children with cerebellar neoplasms. Pediatr Neurosurg. 2011;47(1):51-9.

Forbes JA, Mobley BC, O’Lynnger TM, Cooper CM, Ghiassi M, Hanif R, Pearson MM. Pediatric cerebellar pilomyxoid-spectrum astrocytomas. J Neurosurg Pediatr. 2011 Jul;8(1):90-6.

Fourney DR, Dettori JR, Hall H, Härtl R, McGirt MJ, Daubs MD. A systematic review of clinical pathways for lower back pain and introduction of the Saskatchewan Spine Pathway. Spine. 2011 Oct 1;36(21 Suppl):S164-71. Review.

Grantham DW, Croghan NBH, Camalier CR and Bernstein LR. Binaural interference: the Effects of listening environ-ment and stimulus timing. In: Proceedings of IWPASH: International Workshop on the Principals and Applications of Spatial Hearing 2009, ed Suzuki et al, pp 45-60. World

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scientific publishing, Ltd. Singapore. (2011).

Kajikawa Y, Camalier CR, de la Mothe LA, Blumell S, D’Angelo, WR, Sterbing-D’Angelo SJ, and Hackett TA. Au-ditory cortical tuning to band-pass noise in primate A1 and CM: a comparison to pure tones. Neuroscience Research 2011 Aug; 70 (4): 401-407.

Lee HY, Angelastro JM, Kenney AM, Mason CA, Greene LA. Reciprocal actions of ATF5 and Shh in proliferation of cerebellar granule neuron progenitor cells. Dev Neurobiol. 2011 Sep 19.

McCullough KA, Even JL, Braly BA, Hohl JB, Song Y, Lee JY, McGirt MJ, Devin CJ. Clinical indications for arterial imaging in cervical trauma. Tenn Med. 2011 Sep;104(8):41-2.

Mehta VA, Gottfried ON, McGirt MJ, Gokaslan ZL, Ahn ES, Jallo GI. Safety and efficacy of concurrent pediatric spi-nal cord untethering and deformity correction. J Spinal Disord Tech. 2011 Aug;24(6):401-5.

Mukherjee D, Chaichana KL, Adogwa O, Gokaslan Z, Aaronson O, Cheng JS, McGirt MJ. Association of extent of local tumor invasion and survival in patients with malignant primary osseous spinal neoplasms from the surveillance, epi-demiology, and end results (SEER) database. World Neurosurg. 2011 Dec;76(6):580-5.

Parker SL, Adogwa O, Bydon A, Cheng J, McGirt MJ. Cost-Effectiveness of Minimally Invasive Versus Open Transfo-raminal Lumbar Interbody Fusion for Degenerative Spon-dylolisthesis Associated Low-Back and Leg Pain Over Two Years. World Neurosurg. 2011 Nov 7.

Parker SL, Adogwa O, Davis BJ, Fulchiero E, Aaronson O, Cheng J, Devin CJ, McGirt MJ. Cost-utility Analysis of Mini-mally Invasive Versus Open Multilevel Hemilaminectomy for Lumbar Stenosis. J Spinal Disord Tech. 2011 Sep 28.

Parker SL, Anderson WN, Lilienfeld S, Megerian JT, Mc-Girt MJ. Cerebrospinal shunt infection in patients receiving antibiotic-impregnated versus standard shunts. J Neurosurg Pediatr. 2011 Sep;8(3):259-65. Review.

Parker SL, Amin AG, Farber SH, McGirt MJ, Sciubba DM, Wolinsky JP, Bydon A, Gokaslan ZL, Witham TF. Ability of electromyographic monitoring to determine the presence of malpositioned pedicle screws in the lumbosacral spine: analy-sis of 2450 consecutively placed screws. J Neurosurg Spine. 2011 Aug;15(2):130-5.

Permuth-Wey J, Thompson RC, Nabors LB, Olson JJ, Browning JE, Madden MH, Chen YA, Egan KM. A func-

tional polymorphism in the pre-miR-146a gene is associated with risk an prognosis in adult glioma. Journal of Neuro-Oncolo-gy, 105(3):639-46, 2011.

Wang MY, Lerner J, Lesko J, McGirt MJ. Acute Hospital Costs After Minimally Invasive Versus Open Lumbar Interbody Fu-sion: Data From a US National Database With 6106 Patients. J Spinal Disord Tech. 2011 Jun 16.

Pediatric SurgeryBaregamian N, Song J, Papaconstantinou J, Hawkins H, Evers BM, Chung DH. Intestinal mitochondrial apoptotic signal-ing is activated during oxidative stress. Pediatr Surg Int 2011 Aug;27(8):871-7.

Colon N, Chung DH. Neuroblastoma. Adv Pediatr 2011;58(1):297-311.

Osborn CY, Rosenbloom ST, Stenner S, Anders S, Muse S, Johnson KB, Jirjis J, Jackson GP. MyHealthAtVanderbilt: Policies and procedures governing a patient portal. J Am Med Inform Assoc 2011 Dec;18 Suppl 1:i18-23.

Paul P, Gillory LA, Kang J, Qiao J, Chung DH. Targeting gastrin-releasing peptide as a new approach to treat aggressive refractory neuroblastomas. Surgery 2011 Mar;149(3):425-32

Rosenbloom ST, Daniels TL, Talbot TR, McClain T, Hennes R, Stenner S, Muse S, Jirjis J, Jackson GP. Triaging patients at risk of influenza using a patient portal. J Am Med Inform Assoc. 2011 Dec. 1. Epub ahead of print.

Shelton J, Jackson GP. Palliative care and pediatric surgery. Surg Clin North Am 2011 Apr;91(2):419-28, ix.

Taylor C, Qiao J, Colon N, Schlegel C, Josifi E, Chung DH. Integrin-linked kinase regulates PTEN activity to pro-mote tumorigenesis in neuroblastoma cells. Surgery 2011 Aug;150(2):162-8

Plastic SurgeryAdolph EJ, Hafeman AE, Davidson JM, Nanney LB, Guelcher SA. Injectable polyurethane composite scaffolds delay wound contraction and support infiltration and remodeling in rat excisional wounds. J Biomed Mater Res A. 2011 Nov 21. doi: 10.1002/jbm.a.33266. [Epub ahead of print]

Higdon KK, Berry JM, Shack RB. “Anesthesia and Safety Considerations in the Perioperative Period,” Encyclopedia of Body Sculpting After Massive Weight Loss, Strauch/Herman, pg. 31 II General Considerations. 2011.

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Spear, M. Wound cleansing: solutions and techniques. Plastic Surgical Nursing. 2011 Jan-Mar; 31(1), 29-31.

Spear, M. Wound photography: Considerations and recom-mendations. Plastic Surgical Nursing. 2011 Apr-Jun;31(2), 82-83.

Spear, M. The biofilm challenge: Breaking down the walls. Plastic Surgical Nursing. 2011 Jul-Sep;31(3), 117-20.

Spear, M. Infected? Or Not? Plastic Surgical Nursing. 2011 Oct-Dec;31(4), 174-175.

Taverna D, Nanney LB, Pollins AC, Sindona G, Caprioli R. Mutiplexed molecular descriptors of pressure ulcers defined by imaging mass spectrometry. Wound Repair Regen. 2011 Nov;19(6):734-44. doi: 10.1111/j.1524-475X.2011.00738.x. [Epub 2011 Oct 19.]

Taverna D, Nanney LB, Pollins AC, Sindona G, Caprioli R. Spatial mapping by mass spectrometry offers advancements for rapid definition of human skin proteomic signatures. Exp Dermatol. 2011 Aug;20(8):642-7.

Thayer WP, Shack RB. “Soft Tissue Coverage I: Radial Forearm Flap,” Shoulder and Elbow Surgery, pgs. 1036-1044, Procedure 62, 2011.

Thayer WP, Shack RB. “Soft Tissue Coverage II: Latissimus Dorsi Flap,” Shoulder and Elbow Surgery, pgs. 1046-1053, Procedure 62, 2011.

Thayer WP, Shack RB. “Soft Tissue Coverage III: Posterior Interosseous Flap,” Shoulder and Elbow Surgery, pgs. 1056-1060, Procedure 62, 2011.

Thayer WP, Shack RB. “Soft Tissue Coverage IV: Brachiora-dialis Muscle Flap,” Shoulder and Elbow Surgery, pgs. 1062-1067, Procedure 62, 2011.

Thayer WP, Shack RB. “Soft Tissue Coverage V: Reverse Lat-eral Arm Flap,” Shoulder and Elbow Surgery, pgs. 1070-1075, Procedure 62, 2011.

Thoracic SurgeryChokkalingam AP, Bartley K, Wiemels JL, Metayer C, Bar-cellos LF, Hansen HM, Aldrich MC, Guha N, Urayama KY, Scelo G, Chang JS, Month SR, Wiencke JK, Buffler PA. Haplotypes of DNA repair and cell cycle control genes, X-ray exposures, and risk of childhood acute lymphoblastic leuke-mia. Cancer Causes and Control. 2011 Dec 22(12):1721-30.

Galanter JM, Torgerson D, Gignoux CR, Sen S, Roth L, Eng C, Huntsman S, Via M, Aldrich MC, Rodriguez-Cintron W, Rodriguez-Santana J, Chapela R, Ford JG, Burchard EG. Cosmopolitan and ethnic-specific replication of genetic risk

factors for asthma in two diverse Latino populations. J Al-lergy Clin Immun. 2011 Jul; 128(1):37-43.

Hinch AG, Tandon A, Patterson N, Song Y, Rohland N, Palmer CD, Chen GK, Wang K, Buxbaum SG, Akylbekova EL, Aldrich MC, Ambrosone CB, Amos C, Bandera EV, Berndt SI, Bernstein L, Blot WJ, Bock CH, Boerwinkle E, Cai Q, Caporaso N, Casey G, Cupples LA, Deming SL, Diver WR, Divers J, Fornage M, Gillanders EM, Glessner J, Harris CC, Hu JJ, Ingles SA, Isaacs W, John EM, Kao WH, Keating B, Kittles RA, Kolonel LN, Larkin E, Le Marchand L, McNeill LH, Millikan RC, Murphy A, Musani S, Neslund-Dudas C, Nyante S, Papanicolaou GJ, Press MF, Psaty BM, Reiner AP, Rich SS, Rodriguez-Gil JL, Rotter JI, Rybicki BA, Schwartz AG, Signorello LB, Spitz M, Strom SS, Thun MJ, Tucker MA, Wang Z, Wiencke JK, Witte JS, Wrensch M, Wu X, Yamamura Y, Zanetti KA, Zheng W, Ziegler RG, Zhu X, Redline S, Hirschhorn JN, Henderson BE, Taylor HA Jr, Price AL, Hakonarson H, Chanock SJ, Haiman CA, Wilson JG, Reich D, Myers SR. The landscape of recombination in African Americans. Nature. 2011 Jul 20;476(7359):170-5.

Metayer C, Scelo G, Chokkalingam AP, Barcellos LF, Aldrich MC, Chang JS, Guha N, Urayama KY, Hansen HM, Block G, Kiley V, Wiencke JW, Wiemels JL, Buffler PA. Genetic variants in the folate pathway and risk of childhood acute lymphoblastic leukemia. Cancer Causes and Control. 2011 Sep 22(9):1243-58.

Soler Artigas MS, Loth DW, Wain LV, Gharib SA, Obei-dat M, Tang W, Zhai G, Zhao JH, Smith AV, Huffman JE, Albrecht E, Jackson CM, Evans DM, Cadby G, Fornage M, Manichaikul A, Lopez LM, Johnson T, Aldrich MC, Aspe-lund T, Barroso I, Campbell H, Cassano PA, Couper DJ, Eiriksdottir G, Franceschini N, Garcia M, Gieger C, Gislason GK, Grkovic I, Hammond CJ, Hancock DB, Harris TB, Ramasamy A, Heckbert SR, Heliövaara M, Homuth G, Hysi PG, James AL, Jankovic S, Joubert BR, Karrasch S, Klopp N, Koch B, Kritchevsky SB, Launer LJ, Liu Y, Loehr LR, Lohman K, Loos RJ, Lumley T, Al Balushi KA, Ang WQ, Barr RG, Beilby J, Blakey JD, Boban M, Boraska V, Brisman J, Britton JR, Brusselle GG, Cooper C, Curjuric I, Dahgam S, Deary IJ, Ebrahim S, Eijgelsheim M, Francks C, Gaysina D, Granell R, Gu X, Hankinson JL, Hardy R, Harris SE, Hen-derson J, Henry A, Hingorani AD, Hofman A, Holt PG, Hui J, Hunter ML, Imboden M, Jameson KA, Kerr SM, Kolcic I, Kronenberg F, Liu JZ, Marchini J, McKeever T, Morris AD, Olin AC, Porteous DJ, Postma DS, Rich SS, Ring SM, Rivadeneira F, Rochat T, Sayer AA, Sayers I, Sly PD, Smith GD, Sood A, Starr JM, Uitterlinden AG, Vonk JM, Wanna-methee SG, Whincup PH, Wijmenga C, Williams OD, Wong

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A, Mangino M, Marciante KD, McArdle WL, Meibohm B, Morrison AC, North KE, Omenaas E, Palmer LJ, Pietiläinen KH, Pin I, Pola Sbreve Ek O, Pouta A, Psaty BM, Harti-kainen AL, Rantanen T, Ripatti S, Rotter JI, Rudan I, Rud-nicka AR, Schulz H, Shin SY, Spector TD, Surakka I, Vitart V, Völzke H, Wareham NJ, Warrington NM, Wichmann HE, Wild SH, Wilk JB, Wjst M, Wright AF, Zgaga L, Zemunik T, Pennell CE, Nyberg F, Kuh D, Holloway JW, Boezen HM, Lawlor DA, Morris RW, Probst-Hensch N; The International Lung Cancer Consortium; GIANT consortium, Kaprio J, Wilson JF, Hayward C, Kähönen M, Heinrich J, Musk AW, Jarvis DL, Gläser S, Järvelin MR, Ch Stricker BH, Elliott P, O’Connor GT, Strachan DP, London SJ, Hall IP, Gudna-son V, Tobin MD. Genome-wide association and large scale follow-up identifies 16 new loci influencing pulmonary func-tion. Nature Genetics. 2011 Sept 25; 43(11):1082-90.

Urologic SurgeryAnderson CB, Clark PE, Morgan TM, Stratton KL, Herrell SD, Davis R, Cookson MS, Smith JA Jr, Chang SS. Urinary collecting system invasion is a predictor for overall and disease-specific survival in locally invasive renal cell carci-noma. Urology. 2011 Jul;78(1):99-104.

Birkhahn M, Penson DF, Cai J, Groshen S, Stein JP, Lies-kovsky G, Skinner DG, Cote RJ. Long-term outcome in patients with a Gleason score = 6 prostate cancer treated by radical prostatectomy. BJU Int. 2011 Sep;108(5):660-4.

Broughton GJ, Clark PE, Barocas DA, Cookson MS, Smith JA Jr, Herrell SD, Chang SS. Tumour size, tumour complex-ity, and surgical approach are associated with nephrectomy type in small renal cortical tumours treated electively. BJU Int. 2012 Jun;109(11):1607-13.

Cadeddu J, Herman M, Lepor H, Lotan Y, Mottrie A, Patel V, Pruthi R, Rane A, Smith JA Jr. Robotically speaking: Experts consider the current and future state of robotic surgery. Interview by Kevin D. Blanchet. BJU Int. 2011 Sep;108(6).

Clark PE, Polosukhina D, Love H, Correa H, Coffin C, Perl-man EJ, de Caestecker M, Moses HL, Zent R. ß-Catenin and K-RAS synergize to form primitive renal epithelial tumors with features of epithelial Wilms’ tumors. Am J Pathol. 2011 Dec;179(6):3045-55.

Davies JD, Aghazadeh MA, Phillips S, Salem S, Chang SS, Clark PE, Cookson MS, Davis R, Herrell SD, Penson DF, Smith JA Jr, Barocas DA. Prostate size as a predictor of Gleason score upgrading in patients with low risk prostate cancer. J Urol. 2011 Dec;186(6):2221-7.

Degraff DJ, Cates JM, Mauney JR, Clark PE, Matusik RJ, Adam RM. When urothelial differentiation pathways go wrong: Implications for bladder cancer development and progression. Urol Oncol. 2011 Sep 14.

DeGraff DJ, Clark PE. Detection of tumor cells in the bone offers independent prognostic value in bladder cancer patients: the clinical and basic science perspective. Eur Urol. 2011 Aug;60(2):239-40.

Fowke JH, Munro H, Signorello LB, Blot WJ, Penson DF; Urologic Diseases of America Project. Association between socioeconomic status (SES) and lower urinary tract symptom (LUTS) severity among black and white men. J Gen Intern Med. 2011 Nov;26(11):1305-10.

Glisson CL, Altamar HO, Herrell SD, Clark P, Galloway RL. Comparison and assessment of semi-automatic image seg-mentation in computed tomography scans for image-guided kidney surgery. Med Phys. 2011 Nov;38(11):6265-74.

Jiang M, Strand DW, Franco OE, Clark PE, Hayward SW. PPAR?: a molecular link between systemic metabolic disease and benign prostate hyperplasia. Differentiation. 2011 Nov-Dec;82(4-5):220-36.

Lotan Y, Amiel G, Boorjian SA, Clark PE, Droller M, Gin-grich JR, Guzzo TJ, Inman BA, Kamat AM, Karsh L, Nielsen ME, Smith ND, Shariat SF, Svatek RS, Taylor JM; on Behalf of the Bladder Cancer Think Tank, and Bladder Cancer Ad-vocacy Network. Comprehensive handbook for developing a bladder cancer cystectomy database. Urol Oncol. 2011 Nov 4.

Miller NL. The origin and significance of Randall’s plaque in nephrolithiasis. J Urol. 2011 Sep;186(3):783-4. Epub 2011 Jul 23.

Mitchell RE, Clark PE, Scarpero HM. Assessing the surgical skills of urology residents after preurology general surgery training: the surgical skills learning needs of new urology residents. J Surg Educ. 2011 Sep-Oct;68(5):341-6.

Morgan TM, Barocas DA, Chang SS, Phillips SE, Salem S, Clark PE, Penson DF, Smith JA Jr, Cookson MS. The rela-tionship between perioperative blood transfusion and overall mortality in patients undergoing radical cystectomy for blad-der cancer. Urol Oncol. 2011 Sep 7.

Morgan TM, Keegan KA, Barocas DA, Ruhotina N, Phillips SE, Chang SS, Penson DF, Clark PE, Smith JA Jr, Cookson MS. Predicting the probability of 90-day survival of elderly patients with bladder cancer treated with radical cystectomy. J Urol. 2011 Sep;186(3):829-34.

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Motzer RJ, Agarwal N, Beard C, Bhayani S, Bolger GB, Carducci MA, Chang SS, Choueiri TK, Hancock SL, Hudes GR, Jonasch E, Josephson D, Kuzel TM, Levine EG, Lin DW, Margolin KA, Michaelson MD, Olencki T, Pili R, Ratliff TW, Redman BG, Robertson CN, Ryan CJ, Sheinfeld J, Spiess PE, Wang J, Wilder RB; National Comprehensive Cancer Network. Kidney cancer. J Natl Compr Canc Netw. 2011 Sep 1;9(9):960-77. Erratum in: J Natl Compr Canc Netw. 2011 Nov 1;9(11).

Penson DF. Re: Assessment of quality of cancer-related follow-up care from the cancer survivor’s perspective. J Urol. 2011 Dec;186(6):2349.

Penson DF. Re: Validating the patient safety indicators in the Veterans Health Administration: are they ready for prime time? J Urol. 2011 Dec;186(6):2347-8.

Penson DF. Re: Readmissions in the postoperative period fol-lowing urinary diversion. J Urol. 2011 Dec;186(6):2305-6.

Penson DF, Munro HM, Signorello LB, Blot WJ, Fowke JH; Urologic Diseases in America Project. Obesity, physical activ-ity and lower urinary tract symptoms: results from the South-ern Community Cohort Study. J Urol. 2011 Dec;186(6):2316-22.

Reynolds WS, Dmochowski RR, Penson DF. Epidemiology of stress urinary incontinence in women. Curr Urol Rep. 2011 Oct;12(5):370-6.

Semins MJ, Bartik L, Chew BH, Hyams ES, Humphreys M, Miller NL, Shah O, Paterson RF, Matlaga BR. Multicenter analysis of postoperative CT findings after percutaneous nephrolithotomy: defining complication rates. Urology. 2011 Aug;78(2):291-4.

Stabler S, Koyama T, Zhao Z, Martinez-Ferrer M, Al-len RH, Luka Z, Loukachevitch LV, Clark PE, Wagner C, Bhowmick NA. Serum methionine metabolites are risk fac-tors for metastatic prostate cancer progression. PLoS One. 2011;6(8):e22486.

Smith AB, Raynor M, Amling CL, Busby JE, Castle E, Davis R, Nielsen M, Thomas R, Wallen EM, Woods M, Pruthi RS. Multi-institutional analysis of robotic radical cystectomy for bladder cancer: perioperative outcomes and complications in 227 patients. J Laparoendosc Adv Surg Tech A. 2012 Jan-Feb;22(1):17-21.

Viprakasit DP, Sawyer MD, Herrell SD, Miller NL. Limita-tions of ultrasonography in the evaluation of urolithiasis: a correlation with computed tomography. J Endourol. 2012 Mar;26(3):209-13.

Viprakasit DP, Sawyer MD, Herrell SD, Miller NL. Changing composition of staghorn calculi. J Urol. 2011 Dec;186(6):2285-90.

Viprakasit DP, Derweesh I, Wong C, Su LM, Stroup SP, Bazzi W, Strom KH, Herrell SD. Selective renal parenchymal clamping in robot-assisted laparoscopic partial nephrec-tomy: a multi-institutional experience. J Endourol. 2011 Sep;25(9):1487-91.

Warner JN, Nunez RN, Tyson MD, Viprakasit DP, Miller NL, Humphreys MR. A multiinstitutional study of the ef-fects of medical therapy for lower urinary symptoms on the perioperative outcomes of holmium laser enucleation of the prostate. Urology. 2011 Dec;78(6):1385-90.

Zeliadt SB, Penson DF, Moinpour CM, Blough DK, Fedo-renko CR, Hall IJ, Smith JL, Ekwueme DU, Thompson IM, Keane TE, Ramsey SD. Provider and partner interactions in the treatment decision-making process for newly diagnosed localized prostate cancer. BJU Int. 2011 Sep;108(6):851-6. q

strates commitment, interest and effectiveness in the teach-ing of fellow residents.

Eileen Duggan, M.D., and Ricky Shinall, M.D., M.Div., received The H. William Scott, Jr. Research Scholarship -- given to those residents in General Surgery who have a strong interest in research and exemplify the spirit of Dr. Scott, esteemed chair of Vanderbilt Surgical Sciences from 1952-82.

Jason Castellanos, M.D., Catherine Dale Kling, M.D., and Carmelle Romain, M.D., received The J. Kenneth Jacobs Fellowship in Surgery -- establish to provide funds for support of residents spending one to two years in a re-search laboratory at Vanderbilt or another institution.

Rebeccah Baucom, M.D., received The Lester Williams, Jr. Research Scholarship -- given to that resident whose research proposal shows scientific promise as he/she begins laboratory experience. q

Resident Awards...(Continued from page 4)

It seems so straightforward. If we have pain, we treat it. But what if the pain isn’t so easily located, or it comes and goes, or never seems to go away?

It’s what physicians at the new Vanderbilt Pain Management Center grapple with every day, and why they now define pain as a disease.

Just like diabetes or heart disease, treating pain requires expertise from a host of specialists, including Surgery, Anesthesiology, Psychiatry, Neurology, Orthopaedics and Rehabilitation.

“We all work together because the causes of pain are as varied as the symptoms and severity,” said Marc Huntoon, M.D., director of the

15

Surgeons and Pain Management Physicians Collaborate for Best Outcomes

Vanderbilt Pain Management Center. “By looking at the complete picture, we can develop a comprehensive treat-ment plan that makes sense for each patient,” he said.

The first step is in meeting the patient, asking about history of pain, current medications and any recent injuries. At times, necessary medical treatments such as chemotherapy or surgery can also cause pain.

With this information in hand, physicians can then determine the best course of action for patients already in pain, as well as identify those who may be predisposed to future pain.

“Until recently, the treatment of pain wasn’t always considered a part of a patient’s total care regimen. But if we begin to recognize that pain is a dis-ease, then we can treat it in its entirety, before, during and after it starts,”

Huntoon said.

“For one patient, medication may work beautifully and we refer that patient to the Pain Management Cen-ter. For another

patient, surgery or rehabilitation

may prove successful,” said Joseph S. Cheng, M.D., associate professor of Neurological Surgery.

“It really comes down to providing the best possible treatment for the best possible outcome,” he said. q

Joseph S. Cheng, M.D., M.S.

H. William Scott, Jr. Society Honored as New Members Inducted

Sunil K. Geevarghese, M.D., president of the H. William Scott, Jr. Society, paid tribute to the Scott Society’s 40-year an-niversary during Surgical Grand Rounds on June 8, 2012.

While inducting its newest members, Geevarghese reflected on Dr. Scott’s legacy at Vanderbilt and that of his peers and predecessors, dating back to 1925.

“Few medical institutions are blessed to have such a rich history of leaders whose passion for educating future surgeons is as strong as their passion for the art of surgery, itself,” said Geevarghese.

A brief video commemorating the legacy of Vanderbilt’s surgical program, honored Drs. William Stewart Halsted, Barney Brooks, Alfred Blalock, John Sawyers, Robert Richie, Benton Adkins and Jim O’Neill, along with Dr. Scott.

Dr. Scott served as the founding chair of the Section of Surgical Sciences for 30 years from 1952 to 1982.

The Scott Society was established in

1972 to celebrate his life and many contributions to research, patient care and education.

Forty years later, the Scott Society is imple-menting new initiatives, including the develop-ment of formal men-torship opportunities that pair Scott Society members with graduat-ing chief residents in the same discipline, and the creation of the Annual H. William Scott, Jr. Society Lecture in Surgical History.

This year’s newest members, listed below, will also be presented at the An-nual Clinical Congress of the American College of Surgeons this October.

General Surgery Chief ResidentsChristina Bailey, Hugo Bonatti, Tejal Brahmbhatt, Doug Burka, Felicitas Koller, Khubaib Mapara and Kaushik Mukherjee

Surgical Critical Care FellowsSteven Brooks, Neeta Chaudhary, Brad Dennis and Shannon Eastham

Vascular FellowsBryan Fisher and Sara Cederstrand

Pediatric Surgery FellowsColin Martin and Nathan Novotny

Laparoscopic FellowRobert Kelly

Burn FellowCaroline Kim q

40th Anniversary Class of new Scott Society members

Marc Huntoon, M.D.

Vanderbilt University Medical CenterSection of Surgical SciencesD-4303 Medical Center North1161 21st Avenue SouthNashville, TN. 37232-2736

Innovations in Surgery

2012Vanderbilt Department of Surgery Residents

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