control of pertussis

2
185 CONTROL OF PERTUSSIS " XBD=601 XHG=195 YBD=765 YHG=727>WHOoriNG-corrGH, " XBD=664 XHG=621 YBD=758 YHG=735>or " XBD=885 XHG=680 YBD=769 YHG=724>pertussis, " XBD=947 XHG=902 YBD=758 YHG=726>to " XBD=1052 XHG=963 YBD=768 YHG=723>give " XBD=1102 XHG=1068 YBD=758 YHG=723>it " XBD=1171 XHG=1118 YBD=757 YHG=723>its " XBD=1327 XHG=1188 YBD=757 YHG=722>earlier " XBD=225 XHG=148 YBD=810 YHG=776>and " XBD=345 XHG=239 YBD=810 YHG=787>more " XBD=620 XHG=364 YBD=819 YHG=773>appropriate " XBD=750 XHG=632 YBD=807 YHG=784>name " XBD=843 XHG=766 YBD=818 YHG=772>(for " XBD=925 XHG=856 YBD=807 YHG=773>the " XBD=1083 XHG=941 YBD=817 YHG=772>whoop " XBD=1232 XHG=1100 YBD=807 YHG=784>comes " XBD=1328 XHG=1246 YBD=807 YHG=772>late " XBD=188 XHG=148 YBD=858 YHG=834>or " XBD=279 XHG=208 YBD=858 YHG=826>not " XBD=339 XHG=296 YBD=857 YHG=827>at " XBD=434 XHG=353 YBD=865 YHG=822>all), " XBD=482 XHG=449 YBD=856 YHG=822>is " XBD=592 XHG=501 YBD=856 YHG=833>now " XBD=659 XHG=605 YBD=856 YHG=833>on " XBD=747 XHG=677 YBD=855 YHG=822>the " XBD=934 XHG=765 YBD=867 YHG=822>priority " XBD=1019 XHG=951 YBD=855 YHG=821>list " XBD=1079 XHG=1034 YBD=855 YHG=821>of " XBD=1328 XHG=1094 YBD=866 YHG=822>preventive " XBD=346 XHG=147 YBD=906 YHG=872>medicine. " XBD=450 XHG=400 YBD=905 YHG=871>In " XBD=538 XHG=467 YBD=904 YHG=870>the " XBD=674 XHG=557 YBD=905 YHG=870>small " XBD=890 XHG=693 YBD=905 YHG=870>sheltered " XBD=1048 XHG=907 YBD=915 YHG=869>family " XBD=1094 XHG=1061 YBD=905 YHG=870>it " XBD=1203 XHG=1108 YBD=915 YHG=882>may " XBD=1327 XHG=1223 YBD=905 YHG=882>seem " XBD=196 XHG=148 YBD=955 YHG=933>no " XBD=328 XHG=208 YBD=955 YHG=927>worse " XBD=443 XHG=341 YBD=954 YHG=920>than " XBD=615 XHG=455 YBD=954 YHG=919>tedious " XBD=713 XHG=631 YBD=966 YHG=920>and " XBD=976 XHG=732 YBD=965 YHG=920>distressing, " XBD=1071 XHG=996 YBD=954 YHG=920>but " XBD=1267 XHG=1090 YBD=955 YHG=920>mothers " XBD=1332 XHG=1286 YBD=955 YHG=920>of " XBD=250 XHG=148 YBD=1014 YHG=969>large " XBD=423 XHG=268 YBD=1011 YHG=969>broods, " XBD=525 XHG=444 YBD=1003 YHG=968>and " XBD=714 XHG=543 YBD=1003 YHG=962>medical " XBD=825 XHG=733 YBD=1003 YHG=981>men " XBD=887 XHG=844 YBD=1003 YHG=969>in " XBD=980 XHG=904 YBD=1003 YHG=969>the7 " XBD=1134 XHG=993 YBD=1014 YHG=980>poorer " XBD=1264 XHG=1152 YBD=1015 YHG=973>parts " XBD=1329 XHG=1283 YBD=1004 YHG=970>of " XBD=216 XHG=148 YBD=1053 YHG=1030>our " XBD=447 XHG=238 YBD=1052 YHG=1017>industrial " XBD=611 XHG=470 YBD=1058 YHG=1020>towns, " XBD=899 XHG=637 YBD=1064 YHG=1018>particularly " XBD=1049 XHG=920 YBD=1065 YHG=1017>where " XBD=1143 XHG=1072 YBD=1053 YHG=1018>the " XBD=1327 XHG=1168 YBD=1054 YHG=1018>climate " XBD=178 XHG=148 YBD=1101 YHG=1068>is " XBD=338 XHG=208 YBD=1109 YHG=1066>harsh, " XBD=473 XHG=370 YBD=1101 YHG=1066>have " XBD=598 XHG=505 YBD=1112 YHG=1066>long " XBD=791 XHG=629 YBD=1101 YHG=1067>learned " XBD=867 XHG=822 YBD=1102 YHG=1070>to " XBD=1022 XHG=899 YBD=1102 YHG=1067>dread " XBD=1123 XHG=1053 YBD=1102 YHG=1068>the " XBD=1324 XHG=1161 YBD=1103 YHG=1068>disease. " XBD=299 XHG=149 YBD=1161 YHG=1117>Among " XBD=493 XHG=316 YBD=1150 YHG=1115>children " XBD=636 XHG=508 YBD=1151 YHG=1117>under " XBD=731 XHG=651 YBD=1151 YHG=1115>five " XBD=863 XHG=748 YBD=1161 YHG=1128>years " XBD=913 XHG=880 YBD=1151 YHG=1117>it " XBD=1051 XHG=929 YBD=1151 YHG=1117>ranks " XBD=1179 XHG=1068 YBD=1152 YHG=1117>third " XBD=1239 XHG=1195 YBD=1151 YHG=1120>to " XBD=1327 XHG=1256 YBD=1152 YHG=1118>the " XBD=401 XHG=149 YBD=1211 YHG=1165>pneumonias " XBD=519 XHG=438 YBD=1199 YHG=1165>and " XBD=811 XHG=554 YBD=1211 YHG=1164>non-specific " XBD=1028 XHG=848 YBD=1200 YHG=1166>enteritis " XBD=1102 XHG=1058 YBD=1200 YHG=1178>as " XBD=1159 XHG=1135 YBD=1201 YHG=1178>a " XBD=1328 XHG=1188 YBD=1212 YHG=1166>killing " XBD=333 XHG=148 YBD=1249 YHG=1213>infection " XBD=430 XHG=349 YBD=1248 YHG=1213>and " XBD=489 XHG=446 YBD=1249 YHG=1214>in " XBD=699 XHG=506 YBD=1250 YHG=1214>Scotland " XBD=824 XHG=715 YBD=1249 YHG=1226>more " XBD=1020 XHG=844 YBD=1249 YHG=1214>children " XBD=1100 XHG=1036 YBD=1250 YHG=1215>die " XBD=1163 XHG=1119 YBD=1250 YHG=1215>of " XBD=1209 XHG=1175 YBD=1250 YHG=1215>it " XBD=1328 XHG=1226 YBD=1250 YHG=1215>than " XBD=191 XHG=150 YBD=1299 YHG=1262>of " XBD=438 XHG=199 YBD=1310 YHG=1263>diphtheria. " XBD=627 XHG=488 YBD=1299 YHG=1264>About " XBD=665 XHG=640 YBD=1298 YHG=1276>a " XBD=796 XHG=677 YBD=1299 YHG=1264>tenth " XBD=855 XHG=809 YBD=1299 YHG=1264>of " XBD=933 XHG=863 YBD=1299 YHG=1264>the " XBD=1055 XHG=948 YBD=1300 YHG=1276>cases " XBD=1149 XHG=1068 YBD=1300 YHG=1265>and " XBD=1250 XHG=1161 YBD=1299 YHG=1264>half " XBD=1329 XHG=1258 YBD=1300 YHG=1265>the " XBD=287 XHG=150 YBD=1348 YHG=1313>deaths " XBD=426 XHG=310 YBD=1348 YHG=1305>occur " XBD=491 XHG=448 YBD=1348 YHG=1312>in " XBD=584 XHG=513 YBD=1348 YHG=1313>the " XBD=695 XHG=606 YBD=1348 YHG=1313>first " XBD=812 XHG=716 YBD=1359 YHG=1325>year " XBD=881 XHG=835 YBD=1348 YHG=1313>of " XBD=979 XHG=899 YBD=1349 YHG=1313>life. " XBD=1089 XHG=1032 YBD=1349 YHG=1314>As " XBD=1261 XHG=1113 YBD=1349 YHG=1314>serious " XBD=1328 XHG=1284 YBD=1349 YHG=1326>as " XBD=215 XHG=149 YBD=1396 YHG=1362>the " XBD=436 XHG=228 YBD=1407 YHG=1361>mortality " XBD=594 XHG=450 YBD=1408 YHG=1362>figures " XBD=643 XHG=610 YBD=1397 YHG=1362>is " XBD=730 XHG=659 YBD=1398 YHG=1362>the " XBD=840 XHG=744 YBD=1409 YHG=1363>high " XBD=1059 XHG=856 YBD=1399 YHG=1362>incidence " XBD=1121 XHG=1076 YBD=1397 YHG=1363>of " XBD=1328 XHG=1134 YBD=1409 YHG=1363>crippling " XBD=455 XHG=151 YBD=1456 YHG=1410>complications, " XBD=725 XHG=492 YBD=1447 YHG=1412>immediate " XBD=842 XHG=761 YBD=1447 YHG=1413>and " XBD=1040 XHG=876 YBD=1454 YHG=1415>remote, " XBD=1223 XHG=1078 YBD=1458 YHG=1424>among " XBD=1329 XHG=1257 YBD=1447 YHG=1412>the " XBD=302 XHG=150 YBD=1496 YHG=1460>victims " XBD=374 XHG=328 YBD=1495 YHG=1460>of " XBD=476 XHG=393 YBD=1496 YHG=1461>this " XBD=734 XHG=500 YBD=1507 YHG=1449>protracted " XBD=1223 XHG=758 YBD=1497 YHG=1462>infection―bronchitis " XBD=1329 XHG=1249 YBD=1496 YHG=1462>and " XBD=573 XHG=150 YBD=1556 YHG=1509>bronchopneumonia, " XBD=689 XHG=585 YBD=1557 YHG=1510>’lung " XBD=900 XHG=716 YBD=1557 YHG=1511>collapse, " XBD=1231 XHG=920 YBD=1547 YHG=1511>bronchiectasis " XBD=1330 XHG=1250 YBD=1545 YHG=1511>and " XBD=415 XHG=150 YBD=1595 YHG=1559>tuberculosis. " XBD=505 XHG=468 YBD=1595 YHG=1560>A " XBD=733 XHG=520 YBD=1595 YHG=1560>reduction " XBD=791 XHG=748 YBD=1595 YHG=1561>in " XBD=908 XHG=807 YBD=1595 YHG=1560>both " XBD=995 XHG=924 YBD=1595 YHG=1560>the " XBD=1231 XHG=1010 YBD=1605 YHG=1560>morbidity " XBD=1329 XHG=1249 YBD=1595 YHG=1560>and " XBD=352 XHG=150 YBD=1655 YHG=1608>mortality " XBD=418 XHG=373 YBD=1644 YHG=1609>of " XBD=627 XHG=434 YBD=1655 YHG=1609>pertussis " XBD=683 XHG=649 YBD=1644 YHG=1609>is " XBD=904 XHG=704 YBD=1645 YHG=1609>therefore " XBD=951 XHG=925 YBD=1644 YHG=1621>a " XBD=1097 XHG=971 YBD=1656 YHG=1610>prime " XBD=1327 XHG=1118 YBD=1654 YHG=1609>necessity. " XBD=187 XHG=150 YBD=1694 YHG=1659>It " XBD=298 XHG=203 YBD=1704 YHG=1670>may " XBD=364 XHG=314 YBD=1693 YHG=1659>be " XBD=611 XHG=383 YBD=1705 YHG=1659>attempted " XBD=749 XHG=630 YBD=1705 YHG=1659>along " XBD=849 XHG=767 YBD=1694 YHG=1663>two " XBD=967 XHG=866 YBD=1694 YHG=1659>lines " XBD=1031 XHG=986 YBD=1694 YHG=1659>of " XBD=1329 XHG=1046 YBD=1704 YHG=1659>attack-pro- " XBD=344 XHG=148 YBD=1755 YHG=1708>phylactic " XBD=620 XHG=364 YBD=1744 YHG=1709>vaccination " XBD=723 XHG=640 YBD=1744 YHG=1709>and " XBD=854 XHG=744 YBD=1755 YHG=1708>early " XBD=1087 XHG=864 YBD=1755 YHG=1709>.diagnosis. " XBD=276 XHG=196 YBD=1800 YHG=1765>The " XBD=568 XHG=296 YBD=1800 YHG=1765>effectiveness " XBD=634 XHG=588 YBD=1800 YHG=1765>of " XBD=842 XHG=648 YBD=1811 YHG=1766>pertussis " XBD=1024 XHG=861 YBD=1800 YHG=1765>vaccine " XBD=1087 XHG=1044 YBD=1800 YHG=1765>in " XBD=1331 XHG=1105 YBD=1811 YHG=1765>protecting " XBD=319 XHG=151 YBD=1850 YHG=1814>children " XBD=502 XHG=345 YBD=1861 YHG=1815>against " XBD=597 XHG=527 YBD=1850 YHG=1815>the " XBD=776 XHG=624 YBD=1850 YHG=1815>disease " XBD=1000 XHG=801 YBD=1860 YHG=1814>probably " XBD=1202 XHG=1025 YBD=1860 YHG=1814>depends " XBD=1281 XHG=1229 YBD=1849 YHG=1826>on " XBD=1331 XHG=1307 YBD=1849 YHG=1826>a " XBD=310 XHG=150 YBD=1899 YHG=1865>number " XBD=381 XHG=336 YBD=1899 YHG=1864>of " XBD=564 XHG=401 YBD=1907 YHG=1864>factors, " XBD=690 XHG=592 YBD=1899 YHG=1864>such " XBD=761 XHG=717 YBD=1898 YHG=1876>as " XBD=1090 XHG=788 YBD=1910 YHG=1864>smooth-phase " XBD=1263 XHG=1117 YBD=1898 YHG=1864>strains " XBD=1335 XHG=1290 YBD=1898 YHG=1863>of " XBD=293 XHG=149 YBD=1959 YHG=1914>proved " XBD=581 XHG=307 YBD=1960 YHG=1914>antigenicity, " XBD=798 XHG=598 YBD=1959 YHG=1914>adequate " XBD=971 XHG=812 YBD=1959 YHG=1913>dosage, " XBD=1083 XHG=987 YBD=1948 YHG=1913>slow " XBD=1331 XHG=1097 YBD=1959 YHG=1914>absorption " XBD=225 XHG=150 YBD=1997 YHG=1964>and " XBD=390 XHG=248 YBD=2008 YHG=1974>proper " XBD=578 XHG=416 YBD=2009 YHG=1963>spacing " XBD=650 XHG=604 YBD=1997 YHG=1962>of " XBD=741 XHG=670 YBD=1997 YHG=1963>the " XBD=991 XHG=766 YBD=2007 YHG=1962>injections. " XBD=1081 XHG=1045 YBD=1997 YHG=1962>A " XBD=1265 XHG=1106 YBD=2007 YHG=1963>variety " XBD=1335 XHG=1290 YBD=1996 YHG=1962>of " XBD=242 XHG=147 YBD=2047 YHG=2015>tests " XBD=334 XHG=272 YBD=2047 YHG=2012>for " XBD=559 XHG=364 YBD=2057 YHG=2013>assessing " XBD=703 XHG=589 YBD=2046 YHG=2011>these " XBD=884 XHG=734 YBD=2046 YHG=2011>factors " XBD=1182 XHG=914 YBD=2056 YHG=2011>individually " XBD=1257 XHG=1214 YBD=2046 YHG=2023>or " XBD=1331 XHG=1288 YBD=2046 YHG=2011>in " XBD=415 XHG=151 YBD=2097 YHG=2061>combination " XBD=561 XHG=457 YBD=2096 YHG=2061>have " XBD=708 XHG=605 YBD=2096 YHG=2061>been " XBD=862 XHG=751 YBD=2095 YHG=2061>used. " XBD=1024 XHG=915 YBD=2095 YHG=2060>Thus " XBD=1330 XHG=1069 YBD=2095 YHG=2061>DAUGHTRY- " XBD=388 XHG=149 YBD=2154 YHG=2111>DENMARK,1 " XBD=520 XHG=405 YBD=2156 YHG=2111>using " XBD=608 XHG=537 YBD=2145 YHG=2110>the " XBD=1082 XHG=627 YBD=2155 YHG=2109>complement-fixation " XBD=1180 XHG=1099 YBD=2144 YHG=2109>and " XBD=1331 XHG=1196 YBD=2155 YHG=2109>agglu- " XBD=318 XHG=150 YBD=2196 YHG=2160>tination " XBD=556 XHG=344 YBD=2202 YHG=2160>reactions, " XBD=808 XHG=588 YBD=2194 YHG=2159>concluded " XBD=929 XHG=836 YBD=2194 YHG=2159>that " XBD=1002 XHG=959 YBD=2193 YHG=2171>as " XBD=1147 XHG=1029 YBD=2193 YHG=2158>small " XBD=1200 XHG=1175 YBD=2193 YHG=2171>a " XBD=1332 XHG=1228 YBD=2194 YHG=2159>total " XBD=288 XHG=150 YBD=2254 YHG=2211>dosage " XBD=356 XHG=313 YBD=2244 YHG=2222>as |>" XBD=445 XHG=385 YBD=2244 YHG=2212>1’5 " XBD=585 XHG=474 YBD=2244 YHG=2221>c.cm. " XBD=659 XHG=614 YBD=2243 YHG=2209>of " XBD=1075 XHG=680 YBD=2253 YHG=2208>alum-precipitated " XBD=1264 XHG=1101 YBD=2242 YHG=2208>vaccine " XBD=1335 XHG=1289 YBD=2242 YHG=2208>of " XBD=282 XHG=150 YBD=2300 YHG=2260>40,000 " XBD=469 XHG=315 YBD=2293 YHG=2258>million " XBD=725 XHG=503 YBD=2303 YHG=2258>organisms " XBD=828 XHG=759 YBD=2303 YHG=2269>per " XBD=976 XHG=864 YBD=2292 YHG=2267>c.cm. " XBD=1115 XHG=1013 YBD=2302 YHG=2269>gave " XBD=1193 XHG=1150 YBD=2291 YHG=2269>as " XBD=1333 XHG=1228 YBD=2302 YHG=2257>good " XBD=370 XHG=152 YBD=2352 YHG=2307>protection " XBD=428 XHG=385 YBD=2341 YHG=2319>as " XBD=493 XHG=446 YBD=2341 YHG=2309>14 " XBD=623 XHG=509 YBD=2341 YHG=2296>c.cm. " XBD=685 XHG=640 YBD=2341 YHG=2306>of " XBD=721 XHG=697 YBD=2340 YHG=2318>a " XBD=908 XHG=737 YBD=2351 YHG=2306>straight " XBD=1087 XHG=923 YBD=2340 YHG=2306>vaccine " XBD=1333 XHG=1104 YBD=2351 YHG=2306>containing " XBD=283 XHG=153 YBD=2397 YHG=2357>10,000 " XBD=455 XHG=304 YBD=2390 YHG=2355>million " XBD=717 XHG=482 YBD=2401 YHG=2356>organisms , " XBD=798 XHG=729 YBD=2400 YHG=2366>per " XBD=962 XHG=826 YBD=2389 YHG=2366>c.cm.. " XBD=1226 XHG=989 YBD=2391 YHG=2356>MISHULOW " XBD=1334 XHG=1253 YBD=2390 YHG=2355>and " XBD=217 XHG=151 YBD=2440 YHG=2404>her colleagues " XBD=645 XHG=475 YBD=2450 YHG=2404>2 prefer " XBD=743 XHG=672 YBD=2439 YHG=2404>the " XBD=1152 XHG=769 YBD=2450 YHG=2404>mouse-protective " XBD=1260 XHG=1179 YBD=2439 YHG=2407>test " XBD=1331 XHG=1287 YBD=2439 YHG=2408>to " XBD=310 XHG=151 YBD=2489 YHG=2454>in-vitro " XBD=538 XHG=340 YBD=2488 YHG=2454>reactions " XBD=612 XHG=567 YBD=2488 YHG=2466>as " XBD=701 XHG=648 YBD=2488 YHG=2465>an " XBD=851 XHG=730 YBD=2489 YHG=2454>index " XBD=927 XHG=883 YBD=2488 YHG=2453>of " XBD=1185 XHG=957 YBD=2499 YHG=2454>immunity, " XBD=1332 XHG=1216 YBD=2489 YHG=2453>while " XBD=366 XHG=152 YBD=2537 YHG=2503>FLOSDORF " XBD=463 XHG=383 YBD=2537 YHG=2503>and others " XBD=763 XHG=629 YBD=2537 YHG=2503>3 have " XBD=985 XHG=779 YBD=2537 YHG=2503>described " XBD=1024 XHG=1001 YBD=2537 YHG=2514>a " XBD=1129 XHG=1041 YBD=2537 YHG=2514>new " XBD=1235 XHG=1145 YBD=2537 YHG=2503>skin " XBD=1332 XHG=1250 YBD=2537 YHG=2506>test " XBD=261 XHG=152 YBD=2597 YHG=2551>using " XBD=450 XHG=282 YBD=2596 YHG=2551>purified " XBD=665 XHG=472 YBD=2596 YHG=2552>pertussis " XBD=983 XHG=690 YBD=2597 YHG=2551>agglutinogen, " XBD=1137 XHG=1008 YBD=2587 YHG=2552>which " XBD=1203 XHG=1161 YBD=2586 YHG=2551>in " XBD=1331 XHG=1227 YBD=2586 YHG=2551>their " XBD=375 XHG=152 YBD=2646 YHG=2601>experience " XBD=698 XHG=407 YBD=2646 YHG=2600>distinguished " XBD=800 XHG=730 YBD=2635 YHG=2601>the " XBD=1092 XHG=834 YBD=2646 YHG=2601>susceptibles " XBD=1228 XHG=1124 YBD=2635 YHG=2600>from " XBD=1331 XHG=1261 YBD=2635 YHG=2601>the " XBD=350 XHG=151 YBD=2684 YHG=2648>immunes. " XBD=486 XHG=404 YBD=2683 YHG=2650>The " XBD=623 XHG=508 YBD=2684 YHG=2650>other " XBD=764 XHG=643 YBD=2684 YHG=2650>much " XBD=893 XHG=783 YBD=2684 YHG=2661>more " XBD=1083 XHG=913 YBD=2684 YHG=2639>difficult " XBD=1179 XHG=1104 YBD=2684 YHG=2650>but " XBD=1327 XHG=1200 YBD=2684 YHG=2661>essen- " XBD=219 XHG=151 YBD=2731 YHG=2697>tial " XBD=404 XHG=241 YBD=2732 YHG=2698>method " XBD=472 XHG=428 YBD=2732 YHG=2698>of " XBD=724 XHG=492 YBD=2743 YHG=2699>estimating " XBD=817 XHG=748 YBD=2732 YHG=2698>the " XBD=960 XHG=841 YBD=2732 YHG=2698>value " XBD=1028 XHG=982 YBD=2732 YHG=2698>of " XBD=1326 XHG=1048 YBD=2743 YHG=2697>prophylactic " XBD=396 XHG=151 YBD=2780 YHG=2746>vaccination " XBD=450 XHG=418 YBD=2780 YHG=2746>is " XBD=543 XHG=472 YBD=2781 YHG=2747>the " XBD=787 XHG=566 YBD=2781 YHG=2746>controlled " XBD=901 XHG=807 YBD=2781 YHG=2746>field " XBD=1027 XHG=921 YBD=2781 YHG=2746>trial. " XBD=1238 XHG=1080 YBD=2792 YHG=2747>Among " XBD=1330 XHG=1260 YBD=2781 YHG=2747>the " XBD=235 XHG=152 YBD=2829 YHG=2794>best " XBD=399 XHG=255 YBD=2829 YHG=2795>known " XBD=466 XHG=422 YBD=2829 YHG=2794>of " XBD=596 XHG=483 YBD=2830 YHG=2795>these " XBD=688 XHG=621 YBD=2830 YHG=2808>are " XBD=783 XHG=712 YBD=2830 YHG=2796>the " XBD=956 XHG=805 YBD=2830 YHG=2796>studies " XBD=1023 XHG=979 YBD=2829 YHG=2795>of |>" XBD=1186 XHG=1043 YBD=2830 YHG=2796>PEARL |>" XBD=1327 XHG=1212 YBD=2829 YHG=2796>KEN- ICK and " XBD=466 XHG=397 YBD=2878 YHG=2844>her " XBD=811 XHG=488 YBD=2879 YHG=2844>fellow-workers " XBD=879 XHG=835 YBD=2879 YHG=2849>at " XBD=1039 XHG=902 YBD=2880 YHG=2845>Grand " XBD=1231 XHG=1062 YBD=2891 YHG=2844>Rapids. " XBD=1335 XHG=1280 YBD=2878 YHG=2845>In " XBD=257 XHG=151 YBD=2926 YHG=2892>three " XBD=497 XHG=281 YBD=2927 YHG=2893>successive " XBD=633 XHG=520 YBD=2928 YHG=2893>trials " XBD=710 XHG=658 YBD=2928 YHG=2905>on " XBD=786 XHG=733 YBD=2927 YHG=2905>an " XBD=1014 XHG=810 YBD=2928 YHG=2893>extensive " XBD=1142 XHG=1039 YBD=2927 YHG=2893>scale " XBD=1236 XHG=1166 YBD=2927 YHG=2893>she " XBD=1331 XHG=1258 YBD=2927 YHG=2893>has " XBD=281 XHG=152 YBD=2974 YHG=2941>shown " XBD=404 XHG=313 YBD=2975 YHG=2940>that " XBD=493 XHG=440 YBD=2984 YHG=2942>(1) " XBD=638 XHG=521 YBD=2987 YHG=2941>plain " XBD=863 XHG=671 YBD=2987 YHG=2942>pertussis " XBD=1061 XHG=896 YBD=2976 YHG=2942>vaccine " XBD=1136 XHG=1094 YBD=2976 YHG=2942>in " XBD=1194 XHG=1170 YBD=2976 YHG=2953>a " XBD=1332 XHG=1228 YBD=2976 YHG=2942>total " XBD=291 XHG=152 YBD=3034 YHG=2989>dosage " XBD=360 XHG=317 YBD=3023 YHG=2989>of " XBD=521 XHG=383 YBD=3030 YHG=2991>70,000 " XBD=702 XHG=546 YBD=3025 YHG=2990>million " XBD=948 XHG=728 YBD=3035 YHG=2991>organisms " XBD=1016 XHG=973 YBD=3025 YHG=2990>in " XBD=1155 XHG=1041 YBD=3024 YHG=2991>three " XBD=1333 XHG=1180 YBD=3035 YHG=2990>weekly " XBD=369 XHG=153 YBD=3081 YHG=3036>injections, " XBD=465 XHG=411 YBD=3081 YHG=3039>(2) " XBD=899 XHG=506 YBD=3084 YHG=3039>alum-precipitated " XBD=1100 XHG=937 YBD=3073 YHG=3039>vaccine " XBD=1182 XHG=1138 YBD=3073 YHG=3039>in " XBD=1332 XHG=1220 YBD=3073 YHG=3039>three " XBD=264 XHG=155 YBD=3119 YHG=3085>doses " XBD=332 XHG=290 YBD=3119 YHG=3085>of " XBD=494 XHG=358 YBD=3127 YHG=3087>10,000 " XBD=674 XHG=519 YBD=3121 YHG=3087>million " XBD=918 XHG=700 YBD=3132 YHG=3088>organisms " XBD=988 XHG=945 YBD=3121 YHG=3090>at " XBD=1206 XHG=1013 YBD=3121 YHG=3086>intervals " XBD=1277 XHG=1233 YBD=3122 YHG=3087>of " XBD=1334 XHG=1301 YBD=3128 YHG=3089>1, " XBD=176 XHG=155 YBD=3166 YHG=3134>2 " XBD=330 XHG=204 YBD=3168 YHG=3135>and 5 " XBD=498 XHG=357 YBD=3176 YHG=3134>weeks, " XBD=608 XHG=528 YBD=3170 YHG=3136>and " XBD=693 XHG=638 YBD=3179 YHG=3137>(3) " XBD=746 XHG=723 YBD=3169 YHG=3147>a " XBD=923 XHG=775 YBD=3170 YHG=3135>similar " XBD=1113 XHG=950 YBD=3170 YHG=3137>vaccine " XBD=1337 XHG=1145 YBD=3180 YHG=3136>similarly " XBD=293 XHG=154 YBD=3225 YHG=3183>spaced " XBD=388 XHG=314 YBD=3217 YHG=3183>but " XBD=618 XHG=410 YBD=3218 YHG=3185>combined " XBD=739 XHG=640 YBD=3218 YHG=3185>with " XBD=988 XHG=761 YBD=3229 YHG=3184>diphtheria " XBD=1260 XHG=1010 YBD=3219 YHG=3185>toxoid-all " XBD=1334 XHG=1278 YBD=3217 YHG=3196>re- " XBD=281 XHG=156 YBD=3264 YHG=3230>sulted " XBD=346 XHG=305 YBD=3264 YHG=3231>in " XBD=390 XHG=367 YBD=3265 YHG=3243>a " XBD=522 XHG=404 YBD=3265 YHG=3232>much " XBD=663 XHG=544 YBD=3266 YHG=3232>lower " XBD=887 XHG=684 YBD=3266 YHG=3233>incidence " XBD=954 XHG=909 YBD=3266 YHG=3232>of " XBD=1176 XHG=972 YBD=3277 YHG=3233>pertussis, " XBD=1289 XHG=1192 YBD=3266 YHG=3233>with " XBD=1336 XHG=1312 YBD=3266 YHG=3244>a " XBD=1277 XHG=1097 YBD=143 YHG=120>CONTROL " XBD=1358 XHG=1305 YBD=142 YHG=120>OF " XBD=1599 XHG=1387 YBD=144 YHG=119>PERTUSSIS " XBD=576 XHG=342 YBD=446 YHG=364>THE " XBD=1164 XHG=654 YBD=444 YHG=370>LANCET " XBD=420 XHG=188 YBD=552 YHG=518>LONDON: |>|>" XBD=759 XHG=458 YBD=553 YHG=510>SATURDAY, |>" XBD=1084 XHG=792 YBD=547 YHG=513>FEBRUARY " XBD=1151 XHG=1117 YBD=551 YHG=514>5, " XBD=1276 XHG=1184 YBD=545 YHG=514>1944 1. Danghtry-Denmark, L. Amer. J. Dis. Child. 1942, 63, 453. 2. Mishulow, L., Siegel, M., Leifer, L. and Berkey, S. R. Ibid, 1942, 63, 875. 3. Flosdorf, E. W., Felton. H. M., Bondi, A. and McGuinness, A. C. Amer. J. med. Sci. 1943, 206, 421. 4. Kendrick, P. L. Amer. J. IIyg. 1943, 38, 193. " XBD=1526 XHG=1381 YBD=248 YHG=198>higher " XBD=1779 XHG=1544 YBD=242 YHG=198>proportion " XBD=1842 XHG=1798 YBD=232 YHG=198>of " XBD=1953 XHG=1855 YBD=232 YHG=198>mild " XBD=2080 XHG=1972 YBD=232 YHG=209>cases " XBD=2243 XHG=2098 YBD=242 YHG=209>among " XBD=2334 XHG=2264 YBD=231 YHG=197>the " XBD=2584 XHG=2352 YBD=245 YHG=198>inoculated " XBD=1608 XHG=1381 YBD=290 YHG=245>compared " XBD=1725 XHG=1628 YBD=280 YHG=245>with " XBD=1960 XHG=1746 YBD=280 YHG=247>untreated " XBD=2156 XHG=1983 YBD=280 YHG=246>controls " XBD=2222 XHG=2177 YBD=280 YHG=245>of " XBD=2389 XHG=2240 YBD=279 YHG=245>similar " XBD=2485 XHG=2410 YBD=290 YHG=242>age " XBD=2584 XHG=2504 YBD=280 YHG=247>and " XBD=1564 XHG=1395 YBD=328 YHG=297>status.. " XBD=1678 XHG=1594 YBD=327 YHG=294>The " XBD=1872 XHG=1704 YBD=328 YHG=293>families " XBD=1939 XHG=1898 YBD=328 YHG=294>in " XBD=2039 XHG=1970 YBD=329 YHG=294>the " XBD=2222 XHG=2065 YBD=328 YHG=294>treated " XBD=2371 XHG=2253 YBD=328 YHG=294>series " XBD=2586 XHG=2402 YBD=327 YHG=293>however " XBD=1493 XHG=1392 YBD=376 YHG=353>were " XBD=1559 XHG=1506 YBD=376 YHG=354>on " XBD=1642 XHG=1571 YBD=376 YHG=342>the " XBD=1823 XHG=1654 YBD=387 YHG=354>average " XBD=1995 XHG=1837 YBD=377 YHG=342>smaller " XBD=2107 XHG=2007 YBD=377 YHG=343>than " XBD=2162 XHG=2119 YBD=376 YHG=343>in " XBD=2243 XHG=2173 YBD=377 YHG=343>the " XBD=2411 XHG=2257 YBD=376 YHG=341>control |>" XBD=2584 XHG=2423 YBD=387 YHG=352>groups, " XBD=1520 XHG=1390 YBD=425 YHG=390>which " XBD=1680 XHG=1541 YBD=425 YHG=394>meant " XBD=1776 XHG=1700 YBD=425 YHG=390>less " XBD=2062 XHG=1797 YBD=436 YHG=391>opportunity " XBD=2144 XHG=2082 YBD=426 YHG=392>for " XBD=2352 XHG=2164 YBD=425 YHG=391>intimate " XBD=2582 XHG=2373 YBD=436 YHG=402>exposure. " XBD=1519 XHG=1389 YBD=475 YHG=439>When " XBD=1757 XHG=1535 YBD=474 YHG=439>household " XBD=1989 XHG=1775 YBD=485 YHG=451>exposures " XBD=2105 XHG=2005 YBD=474 YHG=451>were " XBD=2314 XHG=2122 YBD=485 YHG=440>analysed " XBD=2364 XHG=2331 YBD=474 YHG=440>it " XBD=2583 XHG=2381 YBD=485 YHG=440>appeared " XBD=1483 XHG=1389 YBD=523 YHG=489>that " XBD=1681 XHG=1505 YBD=534 YHG=488>30-36% " XBD=1750 XHG=1706 YBD=523 YHG=488>of " XBD=1838 XHG=1767 YBD=523 YHG=488>the " XBD=2096 XHG=1858 YBD=523 YHG=489>vaccinated " XBD=2295 XHG=2118 YBD=523 YHG=489>children " XBD=2397 XHG=2317 YBD=524 YHG=489>and " XBD=2517 XHG=2418 YBD=535 YHG=488>92% " XBD=2587 XHG=2542 YBD=523 YHG=488>of " XBD=1460 XHG=1390 YBD=572 YHG=537>the " XBD=1788 XHG=1492 YBD=572 YHG=538>unvaccinated " XBD=1982 XHG=1819 YBD=573 YHG=537>became " XBD=2200 XHG=2013 YBD=573 YHG=537>infected. " XBD=2349 XHG=2253 YBD=573 YHG=538>This " XBD=2511 XHG=2379 YBD=573 YHG=537>factor " XBD=2589 XHG=2543 YBD=573 YHG=537>of " XBD=1578 XHG=1390 YBD=621 YHG=587>intimate " XBD=1802 XHG=1606 YBD=632 YHG=598>exposure " XBD=2014 XHG=1829 YBD=632 YHG=586>together " XBD=2137 XHG=2040 YBD=621 YHG=587>with " XBD=2409 XHG=2165 YBD=632 YHG=587>inadequate " XBD=2584 XHG=2437 YBD=633 YHG=587>dosage " XBD=1437 XHG=1392 YBD=670 YHG=635>of " XBD=1474 XHG=1450 YBD=670 YHG=647>a " XBD=1664 XHG=1492 YBD=681 YHG=635>straight " XBD=1844 XHG=1681 YBD=670 YHG=637>vaccine " XBD=1956 XHG=1860 YBD=681 YHG=648>may " XBD=2133 XHG=1972 YBD=681 YHG=635>explain " XBD=2219 XHG=2149 YBD=670 YHG=636>the " XBD=2422 XHG=2235 YBD=681 YHG=637>negative " XBD=2584 XHG=2438 YBD=671 YHG=636>results " XBD=1585 XHG=1393 YBD=720 YHG=685>obtained " XBD=1668 XHG=1612 YBD=730 YHG=685>by " XBD=1935 XHG=1693 YBD=720 YHG=679>McFARLAN " XBD=2043 XHG=1963 YBD=719 YHG=685>and " XBD=2240 XHG=2069 YBD=719 YHG=681>TOPLEY " XBD=2267 XHG=2253 YBD=707 YHG=689>5 " XBD=2337 XHG=2294 YBD=719 YHG=685>in " XBD=2388 XHG=2364 YBD=719 YHG=697>a " XBD=2583 XHG=2414 YBD=731 YHG=696>nursery " XBD=1522 XHG=1392 YBD=769 YHG=735>where " XBD=1581 XHG=1537 YBD=769 YHG=735>12 " XBD=1790 XHG=1600 YBD=776 YHG=733>children, " XBD=1932 XHG=1813 YBD=780 YHG=735>given " XBD=2026 XHG=1946 YBD=770 YHG=738>two " XBD=2156 XHG=2041 YBD=769 YHG=734>doses " XBD=2215 XHG=2171 YBD=769 YHG=734>of " XBD=2256 XHG=2232 YBD=770 YHG=747>a " XBD=2412 XHG=2272 YBD=776 YHG=736>20,000 " XBD=2582 XHG=2426 YBD=770 YHG=734>million " XBD=1613 XHG=1393 YBD=830 YHG=785>organisms " XBD=1790 XHG=1626 YBD=819 YHG=785>vaccine " XBD=1900 XHG=1802 YBD=818 YHG=784>with " XBD=1937 XHG=1913 YBD=818 YHG=785>4 " XBD=2078 XHG=1948 YBD=818 YHG=784>weeks " XBD=2281 XHG=2091 YBD=826 YHG=784>between, " XBD=2351 XHG=2296 YBD=818 YHG=783>all " XBD=2584 XHG=2362 YBD=829 YHG=784>developed " XBD=1586 XHG=1392 YBD=879 YHG=829>pertussis " XBD=1678 XHG=1604 YBD=868 YHG=837>not " XBD=1883 XHG=1697 YBD=868 YHG=833>different " XBD=1943 XHG=1900 YBD=867 YHG=833>in " XBD=2138 XHG=1963 YBD=878 YHG=833>severity " XBD=2200 XHG=2157 YBD=867 YHG=844>or " XBD=2318 XHG=2218 YBD=867 YHG=833>time " XBD=2382 XHG=2337 YBD=867 YHG=833>of " XBD=2583 XHG=2397 YBD=878 YHG=833>develop- " XBD=1503 XHG=1391 YBD=918 YHG=886>ment " XBD=1623 XHG=1518 YBD=918 YHG=882>from " XBD=1710 XHG=1638 YBD=918 YHG=883>the " XBD=1919 XHG=1725 YBD=917 YHG=881>infection " XBD=2079 XHG=1933 YBD=928 YHG=880>among " XBD=2143 XHG=2098 YBD=917 YHG=883>12 " XBD=2375 XHG=2160 YBD=917 YHG=882>untreated " XBD=2581 XHG=2391 YBD=917 YHG=882>children. " XBD=1455 XHG=1391 YBD=967 YHG=933>An " XBD=1869 XHG=1473 YBD=978 YHG=931>alum-precipitated " XBD=2079 XHG=1885 YBD=977 YHG=932>pertussis " XBD=2178 XHG=2097 YBD=966 YHG=931>and " XBD=2425 XHG=2195 YBD=977 YHG=931>diphtheria " XBD=2585 XHG=2442 YBD=967 YHG=932>toxoid " XBD=1567 XHG=1391 YBD=1017 YHG=983>mixture " XBD=1659 XHG=1584 YBD=1017 YHG=982>has " XBD=1797 XHG=1676 YBD=1017 YHG=982>much " XBD=1859 XHG=1816 YBD=1017 YHG=984>to " XBD=2131 XHG=1878 YBD=1017 YHG=981>recommend " XBD=2184 XHG=2150 YBD=1016 YHG=981>it " XBD=2582 XHG=2202 YBD=1026 YHG=980>administratively, |>" XBD=1474 XHG=1374 YBD=1066 YHG=1032>and " XBD=1686 XHG=1494 YBD=1069 YHG=1031>ScHtiTZB " XBD=1716 XHG=1701 YBD=1054 YHG=1035>6 " XBD=1809 XHG=1735 YBD=1066 YHG=1031>has " XBD=1966 XHG=1828 YBD=1066 YHG=1031>shown " XBD=2078 XHG=1985 YBD=1066 YHG=1031>that " XBD=2195 XHG=2098 YBD=1066 YHG=1030>such " XBD=2247 XHG=2223 YBD=1066 YHG=1043>a " XBD=2449 XHG=2273 YBD=1066 YHG=1030>mixture " XBD=2512 XHG=2468 YBD=1065 YHG=1031>in " XBD=2584 XHG=2530 YBD=1065 YHG=1042>no " XBD=1482 XHG=1392 YBD=1126 YHG=1092>way " XBD=1708 XHG=1500 YBD=1116 YHG=1080>interferes " XBD=1820 XHG=1722 YBD=1116 YHG=1080>with " XBD=1904 XHG=1833 YBD=1116 YHG=1080>the " XBD=2183 XHG=1920 YBD=1126 YHG=1080>antigenicity " XBD=2242 XHG=2197 YBD=1115 YHG=1080>of " XBD=2379 XHG=2252 YBD=1115 YHG=1080>either " XBD=2585 XHG=2395 YBD=1126 YHG=1085>reagent; " XBD=1469 XHG=1394 YBD=1165 YHG=1130>but " XBD=1522 XHG=1489 YBD=1165 YHG=1130>it " XBD=1660 XHG=1542 YBD=1165 YHG=1133>must " XBD=1723 XHG=1673 YBD=1165 YHG=1130>be " XBD=1866 XHG=1743 YBD=1165 YHG=1131>borne " XBD=1929 XHG=1886 YBD=1164 YHG=1131>in " XBD=2061 XHG=1947 YBD=1165 YHG=1130>mind " XBD=2174 XHG=2081 YBD=1165 YHG=1130>that " XBD=2264 XHG=2193 YBD=1165 YHG=1130>the " XBD=2357 XHG=2284 YBD=1175 YHG=1141>age " XBD=2423 XHG=2377 YBD=1164 YHG=1129>of " XBD=2587 XHG=2446 YBD=1165 YHG=1130>attack " XBD=1424 XHG=1390 YBD=1214 YHG=1180>is " XBD=1623 XHG=1436 YBD=1214 YHG=1180>different " XBD=1678 XHG=1635 YBD=1214 YHG=1180>in " XBD=1759 XHG=1688 YBD=1214 YHG=1179>the " XBD=1851 XHG=1771 YBD=1214 YHG=1183>two " XBD=2075 XHG=1863 YBD=1214 YHG=1179>infections " XBD=2168 XHG=2088 YBD=1214 YHG=1179>and " XBD=2272 XHG=2179 YBD=1214 YHG=1179>that " XBD=2588 XHG=2283 YBD=1214 YHG=1179>immunisation " XBD=1552 XHG=1393 YBD=1274 YHG=1229>against " XBD=1765 XHG=1571 YBD=1275 YHG=1229>pertussis " XBD=1931 XHG=1788 YBD=1264 YHG=1229>should " XBD=2070 XHG=1951 YBD=1274 YHG=1229>begin " XBD=2134 XHG=2090 YBD=1264 YHG=1232>at " XBD=2229 XHG=2155 YBD=1265 YHG=1230>3-6 " XBD=2413 XHG=2249 YBD=1264 YHG=1229>months " XBD=2481 XHG=2435 YBD=1263 YHG=1228>of " XBD=2583 XHG=2497 YBD=1274 YHG=1240>age. LAPIN " XBD=1657 XHG=1543 YBD=1313 YHG=1278>7 has " XBD=1870 XHG=1684 YBD=1324 YHG=1278>disposed " XBD=1943 XHG=1898 YBD=1313 YHG=1278>of " XBD=2041 XHG=1966 YBD=1314 YHG=1290>one " XBD=2175 XHG=2068 YBD=1325 YHG=1279>bogy " XBD=2256 XHG=2200 YBD=1324 YHG=1279>by " XBD=2461 XHG=2283 YBD=1324 YHG=1274>showing " XBD=2583 XHG=2488 YBD=1313 YHG=1279>that " XBD=1546 XHG=1393 YBD=1362 YHG=1327>infants " XBD=1621 XHG=1554 YBD=1362 YHG=1339>are " XBD=1869 XHG=1628 YBD=1373 YHG=1327>apparently " XBD=2205 XHG=1876 YBD=1363 YHG=1328>as immunisable " XBD=2259 XHG=2216 YBD=1363 YHG=1340>as " XBD=2381 XHG=2272 YBD=1363 YHG=1328>older " XBD=2586 XHG=2394 YBD=1369 YHG=1327>children, " XBD=1509 XHG=1393 YBD=1411 YHG=1376>while " XBD=1773 XHG=1528 YBD=1412 YHG=1376>BousplELD " XBD=1802 XHG=1789 YBD=1399 YHG=1380>s " XBD=1894 XHG=1821 YBD=1411 YHG=1377>has " XBD=2042 XHG=1912 YBD=1411 YHG=1377>raised " XBD=2229 XHG=2060 YBD=1412 YHG=1377>another " XBD=2289 XHG=2247 YBD=1411 YHG=1377>in " XBD=2491 XHG=2307 YBD=1422 YHG=1377>pointing " XBD=2584 XHG=2512 YBD=1412 YHG=1381>out " XBD=1487 XHG=1393 YBD=1461 YHG=1426>that " XBD=1533 XHG=1509 YBD=1460 YHG=1437>a " XBD=1788 XHG=1553 YBD=1471 YHG=1425>phenolised " XBD=2001 XHG=1809 YBD=1472 YHG=1426>pertussis " XBD=2185 XHG=2021 YBD=1462 YHG=1427>vaccine " XBD=2341 XHG=2205 YBD=1461 YHG=1426>mixed " XBD=2461 XHG=2362 YBD=1462 YHG=1427>with " XBD=2587 XHG=2482 YBD=1461 YHG=1427>APT " XBD=1436 XHG=1393 YBD=1510 YHG=1476>in " XBD=1527 XHG=1457 YBD=1510 YHG=1475>the " XBD=1708 XHG=1549 YBD=1521 YHG=1475>syringe " XBD=1824 XHG=1728 YBD=1521 YHG=1487>may " XBD=2029 XHG=1842 YBD=1510 YHG=1475>interfere " XBD=2148 XHG=2050 YBD=1511 YHG=1475>with " XBD=2239 XHG=2168 YBD=1510 YHG=1475>the " XBD=2525 XHG=2260 YBD=1521 YHG=1476>antigenicity " XBD=2592 XHG=2546 YBD=1511 YHG=1476>of " XBD=1464 XHG=1394 YBD=1559 YHG=1525>the " XBD=1653 XHG=1485 YBD=1565 YHG=1524>toxoid ; " XBD=1740 XHG=1690 YBD=1559 YHG=1524>he " XBD=2034 XHG=1760 YBD=1559 YHG=1524>recommends " XBD=2237 XHG=2055 YBD=1570 YHG=1528>separate " XBD=2469 XHG=2256 YBD=1569 YHG=1524>injections " XBD=2589 XHG=2490 YBD=1560 YHG=1525>with " XBD=1579 XHG=1396 YBD=1619 YHG=1577>separate " XBD=1778 XHG=1600 YBD=1619 YHG=1573>syringes " XBD=1903 XHG=1799 YBD=1608 YHG=1572>until " XBD=2005 XHG=1923 YBD=1607 YHG=1573>this " XBD=2238 XHG=2024 YBD=1609 YHG=1573>drawback " XBD=2330 XHG=2257 YBD=1608 YHG=1574>has " XBD=2452 XHG=2350 YBD=1609 YHG=1574>been " XBD=2584 XHG=2473 YBD=1609 YHG=1585>over- " XBD=1518 XHG=1396 YBD=1660 YHG=1634>come. " XBD=1610 XHG=1573 YBD=1657 YHG=1623>A " XBD=1820 XHG=1633 YBD=1668 YHG=1623>boosting " XBD=1946 XHG=1852 YBD=1657 YHG=1623>dose " XBD=1993 XHG=1971 YBD=1657 YHG=1623>2 " XBD=2140 XHG=2025 YBD=1668 YHG=1634>years " XBD=2275 XHG=2172 YBD=1657 YHG=1623>after " XBD=2375 XHG=2304 YBD=1658 YHG=1623>the " XBD=2587 XHG=2406 YBD=1669 YHG=1623>primary " XBD=1644 XHG=1395 YBD=1707 YHG=1672>inoculation " XBD=1713 XHG=1669 YBD=1706 YHG=1683>or " XBD=1851 XHG=1736 YBD=1706 YHG=1672>when " XBD=1944 XHG=1874 YBD=1706 YHG=1671>the " XBD=2075 XHG=1969 YBD=1706 YHG=1671>child " XBD=2190 XHG=2098 YBD=1717 YHG=1684>goes " XBD=2258 XHG=2214 YBD=1707 YHG=1676>to " XBD=2418 XHG=2283 YBD=1707 YHG=1672>school " XBD=2588 XHG=2443 YBD=1707 YHG=1672>should " XBD=1571 XHG=1395 YBD=1757 YHG=1722>increase " XBD=1813 XHG=1596 YBD=1756 YHG=1722>resistance " XBD=1916 XHG=1836 YBD=1756 YHG=1721>and " XBD=2030 XHG=1937 YBD=1766 YHG=1721>help " XBD=2097 XHG=2053 YBD=1756 YHG=1725>to " XBD=2321 XHG=2124 YBD=1757 YHG=1721>minimise " XBD=2417 XHG=2347 YBD=1756 YHG=1721>the " XBD=2522 XHG=2439 YBD=1756 YHG=1722>risk " XBD=2591 XHG=2545 YBD=1756 YHG=1722>of " XBD=1590 XHG=1396 YBD=1805 YHG=1770>infection " XBD=1742 XHG=1624 YBD=1816 YHG=1771>being " XBD=1949 XHG=1775 YBD=1816 YHG=1770>brought " XBD=2086 XHG=1982 YBD=1805 YHG=1770>from " XBD=2255 XHG=2120 YBD=1805 YHG=1771>school " XBD=2405 XHG=2287 YBD=1806 YHG=1771>home " XBD=2483 XHG=2438 YBD=1806 YHG=1774>to " XBD=2587 XHG=2517 YBD=1806 YHG=1772>the " XBD=1574 XHG=1395 YBD=1865 YHG=1832>younger " XBD=1791 XHG=1593 YBD=1854 YHG=1821>members " XBD=1856 XHG=1812 YBD=1854 YHG=1820>of " XBD=1942 XHG=1872 YBD=1855 YHG=1820>the " XBD=2114 XHG=1962 YBD=1865 YHG=1819>family. " XBD=2209 XHG=2168 YBD=1855 YHG=1821>It " XBD=2262 XHG=2229 YBD=1854 YHG=1820>is " XBD=2365 XHG=2283 YBD=1855 YHG=1820>still " XBD=2455 XHG=2384 YBD=1855 YHG=1823>too " XBD=2587 XHG=2476 YBD=1865 YHG=1821>early " XBD=1439 XHG=1395 YBD=1904 YHG=1873>to " XBD=1535 XHG=1461 YBD=1915 YHG=1881>say " XBD=1665 XHG=1555 YBD=1904 YHG=1869>what " XBD=1778 XHG=1686 YBD=1915 YHG=1873>part " XBD=1992 XHG=1799 YBD=1915 YHG=1870>pertussis " XBD=2128 XHG=2012 YBD=1904 YHG=1869>toxin " XBD=2264 XHG=2149 YBD=1915 YHG=1869>plays " XBD=2328 XHG=2285 YBD=1904 YHG=1870>in " XBD=2419 XHG=2348 YBD=1904 YHG=1869>the " XBD=2583 XHG=2439 YBD=1915 YHG=1869>patho- " XBD=1549 XHG=1396 YBD=1964 YHG=1919>genesis " XBD=1626 XHG=1581 YBD=1953 YHG=1918>of " XBD=1723 XHG=1652 YBD=1954 YHG=1919>the " XBD=1918 XHG=1754 YBD=1953 YHG=1919>disease. " XBD=2055 XHG=1972 YBD=1953 YHG=1919>The " XBD=2194 XHG=2086 YBD=1953 YHG=1919>work " XBD=2270 XHG=2225 YBD=1953 YHG=1918>of EVANS " XBD=2583 XHG=2456 YBD=1952 YHG=1919>9 and " XBD=1531 XHG=1396 YBD=2002 YHG=1968>others " XBD=1745 XHG=1549 YBD=2003 YHG=1968>indicates " XBD=1863 XHG=1771 YBD=2002 YHG=1968>that " XBD=1970 XHG=1888 YBD=2002 YHG=1968>this " XBD=2225 XHG=1994 YBD=2002 YHG=1967>heat-labile " XBD=2371 XHG=2244 YBD=2008 YHG=1968>toxin, " XBD=2589 XHG=2390 YBD=2002 YHG=1967>liberated " XBD=1453 XHG=1397 YBD=2062 YHG=2018>by " XBD=1697 XHG=1467 YBD=2062 YHG=2016>disrupting " XBD=1782 XHG=1712 YBD=2051 YHG=2017>the " XBD=2019 XHG=1799 YBD=2062 YHG=2017>organisms " XBD=2089 XHG=2033 YBD=2062 YHG=2017>by " XBD=2284 XHG=2103 YBD=2062 YHG=2016>physical " XBD=2497 XHG=2298 YBD=2058 YHG=2016>methods, " XBD=2588 XHG=2515 YBD=2050 YHG=2016>has " XBD=1521 XHG=1395 YBD=2101 YHG=2066>lethal " XBD=1615 XHG=1534 YBD=2101 YHG=2067>and " XBD=1869 XHG=1628 YBD=2112 YHG=2066>necrotising " XBD=2112 XHG=1881 YBD=2112 YHG=2067>properties, " XBD=2208 XHG=2128 YBD=2100 YHG=2066>and " XBD=2314 XHG=2220 YBD=2100 YHG=2066>that " XBD=2350 XHG=2327 YBD=2100 YHG=2077>a " XBD=2588 XHG=2363 YBD=2111 YHG=2066>protective " XBD=1601 XHG=1397 YBD=2150 YHG=2116>antitoxin " XBD=1699 XHG=1623 YBD=2150 YHG=2127>can " XBD=1769 XHG=1720 YBD=2151 YHG=2116>be " XBD=1984 XHG=1789 YBD=2162 YHG=2116>prepared " XBD=2336 XHG=2005 YBD=2162 YHG=2114>experimentally " XBD=2398 XHG=2355 YBD=2149 YHG=2115>in " XBD=2590 XHG=2419 YBD=2149 YHG=2114>animals " XBD=1453 XHG=1398 YBD=2209 YHG=2165>by " XBD=1538 XHG=1468 YBD=2199 YHG=2165>the " XBD=1747 XHG=1553 YBD=2210 YHG=2165>injection " XBD=1808 XHG=1762 YBD=2199 YHG=2164>of " XBD=1972 XHG=1819 YBD=2200 YHG=2166>toxoid. " XBD=2061 XHG=2025 YBD=2200 YHG=2166>A " XBD=2233 XHG=2077 YBD=2211 YHG=2165>specific " XBD=2466 XHG=2250 YBD=2206 YHG=2164>antitoxin, " XBD=2589 XHG=2483 YBD=2200 YHG=2164>how- " XBD=1501 XHG=1397 YBD=2257 YHG=2225>ever, " XBD=1608 XHG=1534 YBD=2248 YHG=2214>has " XBD=1713 XHG=1639 YBD=2248 YHG=2218>not " XBD=1845 XHG=1744 YBD=2248 YHG=2215>been " XBD=2181 XHG=1879 YBD=2249 YHG=2214>demonstrated " XBD=2257 XHG=2213 YBD=2248 YHG=2214>in " XBD=2361 XHG=2290 YBD=2248 YHG=2214>the " XBD=2515 XHG=2392 YBD=2248 YHG=2213>blood " XBD=2593 XHG=2547 YBD=2248 YHG=2213>of " XBD=1590 XHG=1396 YBD=2308 YHG=2264>pertussis " XBD=1823 XHG=1601 YBD=2307 YHG=2263>patients " XBD=1890 XHG=1854 YBD=2297 YHG=2264>A " XBD=2065 XHG=1901 YBD=2298 YHG=2264>vaccine " XBD=2308 XHG=2079 YBD=2308 YHG=2263>containing " XBD=2428 XHG=2327 YBD=2298 YHG=2263>both " XBD=2589 XHG=2446 YBD=2297 YHG=2262>toxoid " XBD=1480 XHG=1399 YBD=2346 YHG=2312>and " XBD=1637 XHG=1505 YBD=2346 YHG=2311>intact " XBD=1841 XHG=1664 YBD=2348 YHG=2312>bacteria " XBD=1970 XHG=1874 YBD=2357 YHG=2324>may " XBD=2117 XHG=1995 YBD=2357 YHG=2324>prove " XBD=2187 XHG=2144 YBD=2346 YHG=2315>to " XBD=2264 XHG=2214 YBD=2347 YHG=2312>be " XBD=2360 XHG=2289 YBD=2345 YHG=2312>the " XBD=2476 XHG=2386 YBD=2346 YHG=2312>best " XBD=2590 XHG=2502 YBD=2356 YHG=2322>pro- " XBD=1553 XHG=1397 YBD=2405 YHG=2361>tecting " XBD=2157 XHG=1572 YBD=2406 YHG=2364>agent. " XBD=1563 XHG=1446 YBD=2452 YHG=2416>Until " XBD=1764 XHG=1578 YBD=2452 YHG=2418>vaccines " XBD=1847 XHG=1780 YBD=2452 YHG=2429>are " XBD=1972 XHG=1862 YBD=2452 YHG=2429>more " XBD=2307 XHG=1989 YBD=2452 YHG=2416>effective-and " XBD=2433 XHG=2322 YBD=2451 YHG=2428>more " XBD=2592 XHG=2448 YBD=2462 YHG=2416>plenti- " XBD=1469 XHG=1397 YBD=2508 YHG=2465>ful, " XBD=1563 XHG=1500 YBD=2501 YHG=2466>for " XBD=1638 XHG=1594 YBD=2501 YHG=2469>at " XBD=1830 XHG=1668 YBD=2511 YHG=2470>present " XBD=2035 XHG=1859 YBD=2501 YHG=2466>demand " XBD=2231 XHG=2066 YBD=2500 YHG=2465>exceeds " XBD=2422 XHG=2263 YBD=2511 YHG=2465>supply, " XBD=2591 XHG=2453 YBD=2511 YHG=2466>partly " XBD=1567 XHG=1397 YBD=2550 YHG=2515>because " XBD=1636 XHG=1590 YBD=2549 YHG=2515>of " XBD=1725 XHG=1654 YBD=2549 YHG=2515>the |>" XBD=1947 XHG=1748 YBD=2559 YHG=2515>difficulty " XBD=2015 XHG=1970 YBD=2549 YHG=2514>of " XBD=2303 XHG=2033 YBD=2560 YHG=2513>preparation, " XBD=2466 XHG=2327 YBD=2559 YHG=2514>partly " XBD=2592 XHG=2489 YBD=2549 YHG=2515>from " XBD=1468 XHG=1397 YBD=2598 YHG=2564>the " XBD=1650 XHG=1494 YBD=2609 YHG=2567>greater " XBD=1844 XHG=1677 YBD=2598 YHG=2564>interest " XBD=1913 XHG=1870 YBD=2597 YHG=2564>in " XBD=2362 XHG=1938 YBD=2608 YHG=2563>prophylaxis-more " XBD=2594 XHG=2389 YBD=2598 YHG=2564>attention " XBD=1543 XHG=1399 YBD=2648 YHG=2613>should " XBD=1615 XHG=1566 YBD=2647 YHG=2613>be " XBD=1758 XHG=1638 YBD=2658 YHG=2613>given " XBD=1824 XHG=1780 YBD=2647 YHG=2615>to " XBD=1988 XHG=1848 YBD=2647 YHG=2611>earlier " XBD=2223 XHG=2010 YBD=2657 YHG=2612>diagnosis. " XBD=2361 XHG=2276 YBD=2647 YHG=2612>The " XBD=2536 XHG=2384 YBD=2653 YHG=2612>disease |>" XBD=2594 XHG=2552 YBD=2647 YHG=2613>is " XBD=1488 XHG=1398 YBD=2696 YHG=2673>now " XBD=1710 XHG=1506 YBD=2706 YHG=2661>generally " XBD=1946 XHG=1728 YBD=2702 YHG=2661>notifiable, " XBD=2049 XHG=1968 YBD=2695 YHG=2661>and " XBD=2169 XHG=2068 YBD=2695 YHG=2661>both " XBD=2329 XHG=2188 YBD=2696 YHG=2661>doctor " XBD=2431 XHG=2349 YBD=2696 YHG=2662>and " XBD=2595 XHG=2449 YBD=2707 YHG=2665>parent " XBD=1544 XHG=1399 YBD=2744 YHG=2710>should " XBD=1611 XHG=1561 YBD=2744 YHG=2711>be " XBD=1879 XHG=1630 YBD=2754 YHG=2708>encouraged " XBD=1941 XHG=1897 YBD=2743 YHG=2712>to " XBD=2096 XHG=1959 YBD=2753 YHG=2712>report " XBD=2201 XHG=2113 YBD=2744 YHG=2709>first " XBD=2329 XHG=2220 YBD=2745 YHG=2721>cases " XBD=2389 XHG=2346 YBD=2744 YHG=2711>in " XBD=2432 XHG=2407 YBD=2744 YHG=2722>a " XBD=2590 XHG=2449 YBD=2745 YHG=2710>house- " XBD=1495 XHG=1398 YBD=2793 YHG=2758>hold " XBD=1568 XHG=1523 YBD=2793 YHG=2769>as " XBD=1710 XHG=1597 YBD=2802 YHG=2757>early " XBD=1782 XHG=1738 YBD=2792 YHG=2769>as " XBD=1983 XHG=1810 YBD=2803 YHG=2757>possible " XBD=2056 XHG=2012 YBD=2792 YHG=2769>so " XBD=2178 XHG=2086 YBD=2793 YHG=2759>that " XBD=2408 XHG=2205 YBD=2794 YHG=2770>measures " XBD=2514 XHG=2439 YBD=2794 YHG=2770>can " XBD=2593 XHG=2543 YBD=2794 YHG=2759>be " XBD=1523 XHG=1398 YBD=2841 YHG=2807>taken " XBD=1581 XHG=1537 YBD=2841 YHG=2810>to " XBD=1755 XHG=1595 YBD=2852 YHG=2807>protect " XBD=1897 XHG=1770 YBD=2848 YHG=2807>other, " XBD=2174 XHG=1912 YBD=2852 YHG=2806>particularly " XBD=2379 XHG=2188 YBD=2853 YHG=2819>younger, " XBD=2593 XHG=2394 YBD=2843 YHG=2810>members " XBD=1445 XHG=1399 YBD=2891 YHG=2855>of " XBD=1540 XHG=1469 YBD=2890 YHG=2855>the " XBD=1722 XHG=1567 YBD=2901 YHG=2855>family. " XBD=1820 XHG=1776 YBD=2889 YHG=2855>If " XBD=2104 XHG=1842 YBD=2900 YHG=2856>satisfactory " XBD=2431 XHG=2130 YBD=2903 YHG=2856>home-nursing " XBD=2493 XHG=2459 YBD=2892 YHG=2858>is " XBD=2596 XHG=2521 YBD=2891 YHG=2861>not " XBD=1573 XHG=1398 YBD=2950 YHG=2904>possible " XBD=1660 XHG=1588 YBD=2939 YHG=2904>the " XBD=1785 XHG=1678 YBD=2938 YHG=2904>child " XBD=1945 XHG=1801 YBD=2939 YHG=2904>should " XBD=2012 XHG=1962 YBD=2939 YHG=2905>be " XBD=2228 XHG=2027 YBD=2940 YHG=2905>admitted " XBD=2288 XHG=2244 YBD=2940 YHG=2909>to " XBD=2493 XHG=2305 YBD=2951 YHG=2906>hospital, " XBD=2594 XHG=2513 YBD=2940 YHG=2906>and " XBD=1596 XHG=1399 YBD=2998 YHG=2953>hospitals " XBD=1718 XHG=1607 YBD=2987 YHG=2957>must " XBD=1897 XHG=1731 YBD=2998 YHG=2953>provide " XBD=2019 XHG=1910 YBD=2988 YHG=2965>more |>" XBD=2217 XHG=2032 YBD=2988 YHG=2953>facilities " XBD=2292 XHG=2229 YBD=2989 YHG=2955>for " XBD=2483 XHG=2304 YBD=2999 YHG=2956>patients " XBD=2595 XHG=2496 YBD=2988 YHG=2955>with " XBD=1605 XHG=1383 YBD=3047 YHG=3003>,pertussis, " XBD=1757 XHG=1627 YBD=3036 YHG=3002>which " XBD=1915 XHG=1776 YBD=3036 YHG=3013>means " XBD=2007 XHG=1934 YBD=3037 YHG=3005>not " XBD=2123 XHG=2027 YBD=3048 YHG=3003>only " XBD=2250 XHG=2140 YBD=3037 YHG=3014>more " XBD=2369 XHG=2270 YBD=3038 YHG=3004>beds " XBD=2464 XHG=2388 YBD=3037 YHG=3003>but " XBD=2594 XHG=2483 YBD=3037 YHG=3014>more " XBD=1501 XHG=1399 YBD=3084 YHG=3051>than " XBD=1593 XHG=1522 YBD=3085 YHG=3051>the " XBD=1788 XHG=1616 YBD=3096 YHG=3062>average " XBD=1982 XHG=1808 YBD=3085 YHG=3049>ratio of " XBD=2138 XHG=1999 YBD=3085 YHG=3062>nurses " XBD=2204 XHG=2160 YBD=3085 YHG=3054>to " XBD=2405 XHG=2225 YBD=3097 YHG=3052>patients " XBD=2463 XHG=2428 YBD=3085 YHG=3051>if " XBD=2595 XHG=2481 YBD=3085 YHG=3051>these " XBD=1580 XHG=1402 YBD=3133 YHG=3099>children " XBD=1677 XHG=1609 YBD=3132 YHG=3110>are " XBD=1749 XHG=1705 YBD=3133 YHG=3102>to " XBD=1828 XHG=1778 YBD=3134 YHG=3099>be " XBD=2044 XHG=1856 YBD=3145 YHG=3098>properly " XBD=2229 XHG=2071 YBD=3136 YHG=3100>nursed. " XBD=2374 XHG=2288 YBD=3135 YHG=3099>The " XBD=2501 XHG=2394 YBD=3133 YHG=3099>child " XBD=2592 XHG=2518 YBD=3132 YHG=3099>has " XBD=1561 XHG=1401 YBD=3192 YHG=3146>usually " XBD=1716 XHG=1575 YBD=3182 YHG=3148>ceased " XBD=1773 XHG=1729 YBD=3182 YHG=3152>to " XBD=1836 XHG=1786 YBD=3182 YHG=3148>be " XBD=2062 XHG=1848 YBD=3183 YHG=3148>infectious " XBD=2130 XHG=2075 YBD=3193 YHG=3148>by " XBD=2212 XHG=2143 YBD=3182 YHG=3148>the " XBD=2305 XHG=2227 YBD=3182 YHG=3148>end " XBD=2364 XHG=2319 YBD=3182 YHG=3147>of " XBD=2443 XHG=2372 YBD=3182 YHG=3147>the " XBD=2595 XHG=2456 YBD=3181 YHG=3147>fourth " XBD=1521 XHG=1401 YBD=3237 YHG=3197>week, " XBD=1624 XHG=1543 YBD=3233 YHG=3196>and " XBD=1677 XHG=1641 YBD=3229 YHG=3196>if " XBD=1900 XHG=1692 YBD=3231 YHG=3196>otherwise " XBD=2005 XHG=1917 YBD=3230 YHG=3196>well " XBD=2116 XHG=2021 YBD=3240 YHG=3208>may " XBD=2183 XHG=2134 YBD=3230 YHG=3196>be " XBD=2446 XHG=2211 YBD=3240 YHG=3195>discharged " XBD=2613 XHG=2463 YBD=3240 YHG=3196>home,. 5. McFarlan, A. M. and Topley, E. Mon. Bull. Min. Hlth, November, 1943, p. 122. 6. Schütze, H. Lancet, 1940, ii, 192. 7. Lapin, J. H. Amer. J. Dis. Child. 1942, 63, 225. 8. Bousfield, G. Med. Off. Nov. 13, 1943, p. 159. 9. Evans, D. G. Lancet, 1942, i, 529. 10. Evans, D. G. and Maitland, H. R. J. Path. Bact. 1939, 48, 465.

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Page 1: CONTROL OF PERTUSSIS

185

CONTROL OF PERTUSSIS

" XBD=601 XHG=195 YBD=765 YHG=727>WHOoriNG-corrGH, " XBD=664 XHG=621 YBD=758 YHG=735>or " XBD=885 XHG=680 YBD=769 YHG=724>pertussis, " XBD=947 XHG=902 YBD=758 YHG=726>to " XBD=1052 XHG=963 YBD=768 YHG=723>give " XBD=1102 XHG=1068 YBD=758 YHG=723>it " XBD=1171 XHG=1118 YBD=757 YHG=723>its " XBD=1327 XHG=1188 YBD=757 YHG=722>earlier" XBD=225 XHG=148 YBD=810 YHG=776>and " XBD=345 XHG=239 YBD=810 YHG=787>more " XBD=620 XHG=364 YBD=819 YHG=773>appropriate " XBD=750 XHG=632 YBD=807 YHG=784>name " XBD=843 XHG=766 YBD=818 YHG=772>(for " XBD=925 XHG=856 YBD=807 YHG=773>the " XBD=1083 XHG=941 YBD=817 YHG=772>whoop " XBD=1232 XHG=1100 YBD=807 YHG=784>comes " XBD=1328 XHG=1246 YBD=807 YHG=772>late" XBD=188 XHG=148 YBD=858 YHG=834>or " XBD=279 XHG=208 YBD=858 YHG=826>not " XBD=339 XHG=296 YBD=857 YHG=827>at " XBD=434 XHG=353 YBD=865 YHG=822>all), " XBD=482 XHG=449 YBD=856 YHG=822>is " XBD=592 XHG=501 YBD=856 YHG=833>now " XBD=659 XHG=605 YBD=856 YHG=833>on " XBD=747 XHG=677 YBD=855 YHG=822>the " XBD=934 XHG=765 YBD=867 YHG=822>priority " XBD=1019 XHG=951 YBD=855 YHG=821>list " XBD=1079 XHG=1034 YBD=855 YHG=821>of " XBD=1328 XHG=1094 YBD=866 YHG=822>preventive" XBD=346 XHG=147 YBD=906 YHG=872>medicine. " XBD=450 XHG=400 YBD=905 YHG=871>In " XBD=538 XHG=467 YBD=904 YHG=870>the " XBD=674 XHG=557 YBD=905 YHG=870>small " XBD=890 XHG=693 YBD=905 YHG=870>sheltered " XBD=1048 XHG=907 YBD=915 YHG=869>family " XBD=1094 XHG=1061 YBD=905 YHG=870>it " XBD=1203 XHG=1108 YBD=915 YHG=882>may " XBD=1327 XHG=1223 YBD=905 YHG=882>seem" XBD=196 XHG=148 YBD=955 YHG=933>no " XBD=328 XHG=208 YBD=955 YHG=927>worse " XBD=443 XHG=341 YBD=954 YHG=920>than " XBD=615 XHG=455 YBD=954 YHG=919>tedious " XBD=713 XHG=631 YBD=966 YHG=920>and " XBD=976 XHG=732 YBD=965 YHG=920>distressing, " XBD=1071 XHG=996 YBD=954 YHG=920>but " XBD=1267 XHG=1090 YBD=955 YHG=920>mothers " XBD=1332 XHG=1286 YBD=955 YHG=920>of" XBD=250 XHG=148 YBD=1014 YHG=969>large " XBD=423 XHG=268 YBD=1011 YHG=969>broods, " XBD=525 XHG=444 YBD=1003 YHG=968>and " XBD=714 XHG=543 YBD=1003 YHG=962>medical " XBD=825 XHG=733 YBD=1003 YHG=981>men " XBD=887 XHG=844 YBD=1003 YHG=969>in " XBD=980 XHG=904 YBD=1003 YHG=969>the7 " XBD=1134 XHG=993 YBD=1014 YHG=980>poorer " XBD=1264 XHG=1152 YBD=1015 YHG=973>parts " XBD=1329 XHG=1283 YBD=1004 YHG=970>of" XBD=216 XHG=148 YBD=1053 YHG=1030>our " XBD=447 XHG=238 YBD=1052 YHG=1017>industrial " XBD=611 XHG=470 YBD=1058 YHG=1020>towns, " XBD=899 XHG=637 YBD=1064 YHG=1018>particularly " XBD=1049 XHG=920 YBD=1065 YHG=1017>where " XBD=1143 XHG=1072 YBD=1053 YHG=1018>the " XBD=1327 XHG=1168 YBD=1054 YHG=1018>climate" XBD=178 XHG=148 YBD=1101 YHG=1068>is " XBD=338 XHG=208 YBD=1109 YHG=1066>harsh, " XBD=473 XHG=370 YBD=1101 YHG=1066>have " XBD=598 XHG=505 YBD=1112 YHG=1066>long " XBD=791 XHG=629 YBD=1101 YHG=1067>learned " XBD=867 XHG=822 YBD=1102 YHG=1070>to " XBD=1022 XHG=899 YBD=1102 YHG=1067>dread " XBD=1123 XHG=1053 YBD=1102 YHG=1068>the " XBD=1324 XHG=1161 YBD=1103 YHG=1068>disease." XBD=299 XHG=149 YBD=1161 YHG=1117>Among " XBD=493 XHG=316 YBD=1150 YHG=1115>children " XBD=636 XHG=508 YBD=1151 YHG=1117>under " XBD=731 XHG=651 YBD=1151 YHG=1115>five " XBD=863 XHG=748 YBD=1161 YHG=1128>years " XBD=913 XHG=880 YBD=1151 YHG=1117>it " XBD=1051 XHG=929 YBD=1151 YHG=1117>ranks " XBD=1179 XHG=1068 YBD=1152 YHG=1117>third " XBD=1239 XHG=1195 YBD=1151 YHG=1120>to " XBD=1327 XHG=1256 YBD=1152 YHG=1118>the" XBD=401 XHG=149 YBD=1211 YHG=1165>pneumonias " XBD=519 XHG=438 YBD=1199 YHG=1165>and " XBD=811 XHG=554 YBD=1211 YHG=1164>non-specific " XBD=1028 XHG=848 YBD=1200 YHG=1166>enteritis " XBD=1102 XHG=1058 YBD=1200 YHG=1178>as " XBD=1159 XHG=1135 YBD=1201 YHG=1178>a " XBD=1328 XHG=1188 YBD=1212 YHG=1166>killing" XBD=333 XHG=148 YBD=1249 YHG=1213>infection " XBD=430 XHG=349 YBD=1248 YHG=1213>and " XBD=489 XHG=446 YBD=1249 YHG=1214>in " XBD=699 XHG=506 YBD=1250 YHG=1214>Scotland " XBD=824 XHG=715 YBD=1249 YHG=1226>more " XBD=1020 XHG=844 YBD=1249 YHG=1214>children " XBD=1100 XHG=1036 YBD=1250 YHG=1215>die " XBD=1163 XHG=1119 YBD=1250 YHG=1215>of " XBD=1209 XHG=1175 YBD=1250 YHG=1215>it " XBD=1328 XHG=1226 YBD=1250 YHG=1215>than" XBD=191 XHG=150 YBD=1299 YHG=1262>of " XBD=438 XHG=199 YBD=1310 YHG=1263>diphtheria. " XBD=627 XHG=488 YBD=1299 YHG=1264>About " XBD=665 XHG=640 YBD=1298 YHG=1276>a " XBD=796 XHG=677 YBD=1299 YHG=1264>tenth " XBD=855 XHG=809 YBD=1299 YHG=1264>of " XBD=933 XHG=863 YBD=1299 YHG=1264>the " XBD=1055 XHG=948 YBD=1300 YHG=1276>cases " XBD=1149 XHG=1068 YBD=1300 YHG=1265>and " XBD=1250 XHG=1161 YBD=1299 YHG=1264>half " XBD=1329 XHG=1258 YBD=1300 YHG=1265>the" XBD=287 XHG=150 YBD=1348 YHG=1313>deaths " XBD=426 XHG=310 YBD=1348 YHG=1305>occur " XBD=491 XHG=448 YBD=1348 YHG=1312>in " XBD=584 XHG=513 YBD=1348 YHG=1313>the " XBD=695 XHG=606 YBD=1348 YHG=1313>first " XBD=812 XHG=716 YBD=1359 YHG=1325>year " XBD=881 XHG=835 YBD=1348 YHG=1313>of " XBD=979 XHG=899 YBD=1349 YHG=1313>life. " XBD=1089 XHG=1032 YBD=1349 YHG=1314>As " XBD=1261 XHG=1113 YBD=1349 YHG=1314>serious " XBD=1328 XHG=1284 YBD=1349 YHG=1326>as" XBD=215 XHG=149 YBD=1396 YHG=1362>the " XBD=436 XHG=228 YBD=1407 YHG=1361>mortality " XBD=594 XHG=450 YBD=1408 YHG=1362>figures " XBD=643 XHG=610 YBD=1397 YHG=1362>is " XBD=730 XHG=659 YBD=1398 YHG=1362>the " XBD=840 XHG=744 YBD=1409 YHG=1363>high " XBD=1059 XHG=856 YBD=1399 YHG=1362>incidence " XBD=1121 XHG=1076 YBD=1397 YHG=1363>of " XBD=1328 XHG=1134 YBD=1409 YHG=1363>crippling" XBD=455 XHG=151 YBD=1456 YHG=1410>complications, " XBD=725 XHG=492 YBD=1447 YHG=1412>immediate " XBD=842 XHG=761 YBD=1447 YHG=1413>and " XBD=1040 XHG=876 YBD=1454 YHG=1415>remote, " XBD=1223 XHG=1078 YBD=1458 YHG=1424>among " XBD=1329 XHG=1257 YBD=1447 YHG=1412>the" XBD=302 XHG=150 YBD=1496 YHG=1460>victims " XBD=374 XHG=328 YBD=1495 YHG=1460>of " XBD=476 XHG=393 YBD=1496 YHG=1461>this " XBD=734 XHG=500 YBD=1507 YHG=1449>protracted " XBD=1223 XHG=758 YBD=1497 YHG=1462>infection―bronchitis " XBD=1329 XHG=1249 YBD=1496 YHG=1462>and" XBD=573 XHG=150 YBD=1556 YHG=1509>bronchopneumonia, " XBD=689 XHG=585 YBD=1557 YHG=1510>’lung " XBD=900 XHG=716 YBD=1557 YHG=1511>collapse, " XBD=1231 XHG=920 YBD=1547 YHG=1511>bronchiectasis " XBD=1330 XHG=1250 YBD=1545 YHG=1511>and" XBD=415 XHG=150 YBD=1595 YHG=1559>tuberculosis. " XBD=505 XHG=468 YBD=1595 YHG=1560>A " XBD=733 XHG=520 YBD=1595 YHG=1560>reduction " XBD=791 XHG=748 YBD=1595 YHG=1561>in " XBD=908 XHG=807 YBD=1595 YHG=1560>both " XBD=995 XHG=924 YBD=1595 YHG=1560>the " XBD=1231 XHG=1010 YBD=1605 YHG=1560>morbidity " XBD=1329 XHG=1249 YBD=1595 YHG=1560>and" XBD=352 XHG=150 YBD=1655 YHG=1608>mortality " XBD=418 XHG=373 YBD=1644 YHG=1609>of " XBD=627 XHG=434 YBD=1655 YHG=1609>pertussis " XBD=683 XHG=649 YBD=1644 YHG=1609>is " XBD=904 XHG=704 YBD=1645 YHG=1609>therefore " XBD=951 XHG=925 YBD=1644 YHG=1621>a " XBD=1097 XHG=971 YBD=1656 YHG=1610>prime " XBD=1327 XHG=1118 YBD=1654 YHG=1609>necessity." XBD=187 XHG=150 YBD=1694 YHG=1659>It " XBD=298 XHG=203 YBD=1704 YHG=1670>may " XBD=364 XHG=314 YBD=1693 YHG=1659>be " XBD=611 XHG=383 YBD=1705 YHG=1659>attempted " XBD=749 XHG=630 YBD=1705 YHG=1659>along " XBD=849 XHG=767 YBD=1694 YHG=1663>two " XBD=967 XHG=866 YBD=1694 YHG=1659>lines " XBD=1031 XHG=986 YBD=1694 YHG=1659>of " XBD=1329 XHG=1046 YBD=1704 YHG=1659>attack-pro-" XBD=344 XHG=148 YBD=1755 YHG=1708>phylactic " XBD=620 XHG=364 YBD=1744 YHG=1709>vaccination " XBD=723 XHG=640 YBD=1744 YHG=1709>and " XBD=854 XHG=744 YBD=1755 YHG=1708>early " XBD=1087 XHG=864 YBD=1755 YHG=1709>.diagnosis." XBD=276 XHG=196 YBD=1800 YHG=1765>The " XBD=568 XHG=296 YBD=1800 YHG=1765>effectiveness " XBD=634 XHG=588 YBD=1800 YHG=1765>of " XBD=842 XHG=648 YBD=1811 YHG=1766>pertussis " XBD=1024 XHG=861 YBD=1800 YHG=1765>vaccine " XBD=1087 XHG=1044 YBD=1800 YHG=1765>in " XBD=1331 XHG=1105 YBD=1811 YHG=1765>protecting" XBD=319 XHG=151 YBD=1850 YHG=1814>children " XBD=502 XHG=345 YBD=1861 YHG=1815>against " XBD=597 XHG=527 YBD=1850 YHG=1815>the " XBD=776 XHG=624 YBD=1850 YHG=1815>disease " XBD=1000 XHG=801 YBD=1860 YHG=1814>probably " XBD=1202 XHG=1025 YBD=1860 YHG=1814>depends " XBD=1281 XHG=1229 YBD=1849 YHG=1826>on " XBD=1331 XHG=1307 YBD=1849 YHG=1826>a" XBD=310 XHG=150 YBD=1899 YHG=1865>number " XBD=381 XHG=336 YBD=1899 YHG=1864>of " XBD=564 XHG=401 YBD=1907 YHG=1864>factors, " XBD=690 XHG=592 YBD=1899 YHG=1864>such " XBD=761 XHG=717 YBD=1898 YHG=1876>as " XBD=1090 XHG=788 YBD=1910 YHG=1864>smooth-phase " XBD=1263 XHG=1117 YBD=1898 YHG=1864>strains " XBD=1335 XHG=1290 YBD=1898 YHG=1863>of" XBD=293 XHG=149 YBD=1959 YHG=1914>proved " XBD=581 XHG=307 YBD=1960 YHG=1914>antigenicity, " XBD=798 XHG=598 YBD=1959 YHG=1914>adequate " XBD=971 XHG=812 YBD=1959 YHG=1913>dosage, " XBD=1083 XHG=987 YBD=1948 YHG=1913>slow " XBD=1331 XHG=1097 YBD=1959 YHG=1914>absorption" XBD=225 XHG=150 YBD=1997 YHG=1964>and " XBD=390 XHG=248 YBD=2008 YHG=1974>proper " XBD=578 XHG=416 YBD=2009 YHG=1963>spacing " XBD=650 XHG=604 YBD=1997 YHG=1962>of " XBD=741 XHG=670 YBD=1997 YHG=1963>the " XBD=991 XHG=766 YBD=2007 YHG=1962>injections. " XBD=1081 XHG=1045 YBD=1997 YHG=1962>A " XBD=1265 XHG=1106 YBD=2007 YHG=1963>variety " XBD=1335 XHG=1290 YBD=1996 YHG=1962>of" XBD=242 XHG=147 YBD=2047 YHG=2015>tests " XBD=334 XHG=272 YBD=2047 YHG=2012>for " XBD=559 XHG=364 YBD=2057 YHG=2013>assessing " XBD=703 XHG=589 YBD=2046 YHG=2011>these " XBD=884 XHG=734 YBD=2046 YHG=2011>factors " XBD=1182 XHG=914 YBD=2056 YHG=2011>individually " XBD=1257 XHG=1214 YBD=2046 YHG=2023>or " XBD=1331 XHG=1288 YBD=2046 YHG=2011>in" XBD=415 XHG=151 YBD=2097 YHG=2061>combination " XBD=561 XHG=457 YBD=2096 YHG=2061>have " XBD=708 XHG=605 YBD=2096 YHG=2061>been " XBD=862 XHG=751 YBD=2095 YHG=2061>used. " XBD=1024 XHG=915 YBD=2095 YHG=2060>Thus " XBD=1330 XHG=1069 YBD=2095 YHG=2061>DAUGHTRY-" XBD=388 XHG=149 YBD=2154 YHG=2111>DENMARK,1 " XBD=520 XHG=405 YBD=2156 YHG=2111>using " XBD=608 XHG=537 YBD=2145 YHG=2110>the " XBD=1082 XHG=627 YBD=2155 YHG=2109>complement-fixation " XBD=1180 XHG=1099 YBD=2144 YHG=2109>and " XBD=1331 XHG=1196 YBD=2155 YHG=2109>agglu-" XBD=318 XHG=150 YBD=2196 YHG=2160>tination " XBD=556 XHG=344 YBD=2202 YHG=2160>reactions, " XBD=808 XHG=588 YBD=2194 YHG=2159>concluded " XBD=929 XHG=836 YBD=2194 YHG=2159>that " XBD=1002 XHG=959 YBD=2193 YHG=2171>as " XBD=1147 XHG=1029 YBD=2193 YHG=2158>small " XBD=1200 XHG=1175 YBD=2193 YHG=2171>a " XBD=1332 XHG=1228 YBD=2194 YHG=2159>total" XBD=288 XHG=150 YBD=2254 YHG=2211>dosage " XBD=356 XHG=313 YBD=2244 YHG=2222>as |>" XBD=445 XHG=385 YBD=2244 YHG=2212>1’5 " XBD=585 XHG=474 YBD=2244 YHG=2221>c.cm. " XBD=659 XHG=614 YBD=2243 YHG=2209>of " XBD=1075 XHG=680 YBD=2253 YHG=2208>alum-precipitated " XBD=1264 XHG=1101 YBD=2242 YHG=2208>vaccine " XBD=1335 XHG=1289 YBD=2242 YHG=2208>of" XBD=282 XHG=150 YBD=2300 YHG=2260>40,000 " XBD=469 XHG=315 YBD=2293 YHG=2258>million " XBD=725 XHG=503 YBD=2303 YHG=2258>organisms " XBD=828 XHG=759 YBD=2303 YHG=2269>per " XBD=976 XHG=864 YBD=2292 YHG=2267>c.cm. " XBD=1115 XHG=1013 YBD=2302 YHG=2269>gave " XBD=1193 XHG=1150 YBD=2291 YHG=2269>as " XBD=1333 XHG=1228 YBD=2302 YHG=2257>good" XBD=370 XHG=152 YBD=2352 YHG=2307>protection " XBD=428 XHG=385 YBD=2341 YHG=2319>as " XBD=493 XHG=446 YBD=2341 YHG=2309>14 " XBD=623 XHG=509 YBD=2341 YHG=2296>c.cm. " XBD=685 XHG=640 YBD=2341 YHG=2306>of " XBD=721 XHG=697 YBD=2340 YHG=2318>a " XBD=908 XHG=737 YBD=2351 YHG=2306>straight " XBD=1087 XHG=923 YBD=2340 YHG=2306>vaccine " XBD=1333 XHG=1104 YBD=2351 YHG=2306>containing" XBD=283 XHG=153 YBD=2397 YHG=2357>10,000 " XBD=455 XHG=304 YBD=2390 YHG=2355>million " XBD=717 XHG=482 YBD=2401 YHG=2356>organisms , " XBD=798 XHG=729 YBD=2400 YHG=2366>per " XBD=962 XHG=826 YBD=2389 YHG=2366>c.cm.. " XBD=1226 XHG=989 YBD=2391 YHG=2356>MISHULOW " XBD=1334 XHG=1253 YBD=2390 YHG=2355>and" XBD=217 XHG=151 YBD=2440 YHG=2404>her colleagues " XBD=645 XHG=475 YBD=2450 YHG=2404>2 prefer " XBD=743 XHG=672 YBD=2439 YHG=2404>the " XBD=1152 XHG=769 YBD=2450 YHG=2404>mouse-protective " XBD=1260 XHG=1179 YBD=2439 YHG=2407>test " XBD=1331 XHG=1287 YBD=2439 YHG=2408>to" XBD=310 XHG=151 YBD=2489 YHG=2454>in-vitro " XBD=538 XHG=340 YBD=2488 YHG=2454>reactions " XBD=612 XHG=567 YBD=2488 YHG=2466>as " XBD=701 XHG=648 YBD=2488 YHG=2465>an " XBD=851 XHG=730 YBD=2489 YHG=2454>index " XBD=927 XHG=883 YBD=2488 YHG=2453>of " XBD=1185 XHG=957 YBD=2499 YHG=2454>immunity, " XBD=1332 XHG=1216 YBD=2489 YHG=2453>while" XBD=366 XHG=152 YBD=2537 YHG=2503>FLOSDORF " XBD=463 XHG=383 YBD=2537 YHG=2503>and others " XBD=763 XHG=629 YBD=2537 YHG=2503>3 have " XBD=985 XHG=779 YBD=2537 YHG=2503>described " XBD=1024 XHG=1001 YBD=2537 YHG=2514>a " XBD=1129 XHG=1041 YBD=2537 YHG=2514>new " XBD=1235 XHG=1145 YBD=2537 YHG=2503>skin " XBD=1332 XHG=1250 YBD=2537 YHG=2506>test

" XBD=261 XHG=152 YBD=2597 YHG=2551>using " XBD=450 XHG=282 YBD=2596 YHG=2551>purified " XBD=665 XHG=472 YBD=2596 YHG=2552>pertussis " XBD=983 XHG=690 YBD=2597 YHG=2551>agglutinogen, " XBD=1137 XHG=1008 YBD=2587 YHG=2552>which " XBD=1203 XHG=1161 YBD=2586 YHG=2551>in " XBD=1331 XHG=1227 YBD=2586 YHG=2551>their" XBD=375 XHG=152 YBD=2646 YHG=2601>experience " XBD=698 XHG=407 YBD=2646 YHG=2600>distinguished " XBD=800 XHG=730 YBD=2635 YHG=2601>the " XBD=1092 XHG=834 YBD=2646 YHG=2601>susceptibles " XBD=1228 XHG=1124 YBD=2635 YHG=2600>from " XBD=1331 XHG=1261 YBD=2635 YHG=2601>the" XBD=350 XHG=151 YBD=2684 YHG=2648>immunes. " XBD=486 XHG=404 YBD=2683 YHG=2650>The " XBD=623 XHG=508 YBD=2684 YHG=2650>other " XBD=764 XHG=643 YBD=2684 YHG=2650>much " XBD=893 XHG=783 YBD=2684 YHG=2661>more " XBD=1083 XHG=913 YBD=2684 YHG=2639>difficult " XBD=1179 XHG=1104 YBD=2684 YHG=2650>but " XBD=1327 XHG=1200 YBD=2684 YHG=2661>essen-" XBD=219 XHG=151 YBD=2731 YHG=2697>tial " XBD=404 XHG=241 YBD=2732 YHG=2698>method " XBD=472 XHG=428 YBD=2732 YHG=2698>of " XBD=724 XHG=492 YBD=2743 YHG=2699>estimating " XBD=817 XHG=748 YBD=2732 YHG=2698>the " XBD=960 XHG=841 YBD=2732 YHG=2698>value " XBD=1028 XHG=982 YBD=2732 YHG=2698>of " XBD=1326 XHG=1048 YBD=2743 YHG=2697>prophylactic" XBD=396 XHG=151 YBD=2780 YHG=2746>vaccination " XBD=450 XHG=418 YBD=2780 YHG=2746>is " XBD=543 XHG=472 YBD=2781 YHG=2747>the " XBD=787 XHG=566 YBD=2781 YHG=2746>controlled " XBD=901 XHG=807 YBD=2781 YHG=2746>field " XBD=1027 XHG=921 YBD=2781 YHG=2746>trial. " XBD=1238 XHG=1080 YBD=2792 YHG=2747>Among " XBD=1330 XHG=1260 YBD=2781 YHG=2747>the" XBD=235 XHG=152 YBD=2829 YHG=2794>best " XBD=399 XHG=255 YBD=2829 YHG=2795>known " XBD=466 XHG=422 YBD=2829 YHG=2794>of " XBD=596 XHG=483 YBD=2830 YHG=2795>these " XBD=688 XHG=621 YBD=2830 YHG=2808>are " XBD=783 XHG=712 YBD=2830 YHG=2796>the " XBD=956 XHG=805 YBD=2830 YHG=2796>studies " XBD=1023 XHG=979 YBD=2829 YHG=2795>of |>" XBD=1186 XHG=1043 YBD=2830 YHG=2796>PEARL |>" XBD=1327 XHG=1212 YBD=2829 YHG=2796>KEN-

ICK and " XBD=466 XHG=397 YBD=2878 YHG=2844>her " XBD=811 XHG=488 YBD=2879 YHG=2844>fellow-workers " XBD=879 XHG=835 YBD=2879 YHG=2849>at " XBD=1039 XHG=902 YBD=2880 YHG=2845>Grand " XBD=1231 XHG=1062 YBD=2891 YHG=2844>Rapids. " XBD=1335 XHG=1280 YBD=2878 YHG=2845>In" XBD=257 XHG=151 YBD=2926 YHG=2892>three " XBD=497 XHG=281 YBD=2927 YHG=2893>successive " XBD=633 XHG=520 YBD=2928 YHG=2893>trials " XBD=710 XHG=658 YBD=2928 YHG=2905>on " XBD=786 XHG=733 YBD=2927 YHG=2905>an " XBD=1014 XHG=810 YBD=2928 YHG=2893>extensive " XBD=1142 XHG=1039 YBD=2927 YHG=2893>scale " XBD=1236 XHG=1166 YBD=2927 YHG=2893>she " XBD=1331 XHG=1258 YBD=2927 YHG=2893>has" XBD=281 XHG=152 YBD=2974 YHG=2941>shown " XBD=404 XHG=313 YBD=2975 YHG=2940>that " XBD=493 XHG=440 YBD=2984 YHG=2942>(1) " XBD=638 XHG=521 YBD=2987 YHG=2941>plain " XBD=863 XHG=671 YBD=2987 YHG=2942>pertussis " XBD=1061 XHG=896 YBD=2976 YHG=2942>vaccine " XBD=1136 XHG=1094 YBD=2976 YHG=2942>in " XBD=1194 XHG=1170 YBD=2976 YHG=2953>a " XBD=1332 XHG=1228 YBD=2976 YHG=2942>total" XBD=291 XHG=152 YBD=3034 YHG=2989>dosage " XBD=360 XHG=317 YBD=3023 YHG=2989>of " XBD=521 XHG=383 YBD=3030 YHG=2991>70,000 " XBD=702 XHG=546 YBD=3025 YHG=2990>million " XBD=948 XHG=728 YBD=3035 YHG=2991>organisms " XBD=1016 XHG=973 YBD=3025 YHG=2990>in " XBD=1155 XHG=1041 YBD=3024 YHG=2991>three " XBD=1333 XHG=1180 YBD=3035 YHG=2990>weekly" XBD=369 XHG=153 YBD=3081 YHG=3036>injections, " XBD=465 XHG=411 YBD=3081 YHG=3039>(2) " XBD=899 XHG=506 YBD=3084 YHG=3039>alum-precipitated " XBD=1100 XHG=937 YBD=3073 YHG=3039>vaccine " XBD=1182 XHG=1138 YBD=3073 YHG=3039>in " XBD=1332 XHG=1220 YBD=3073 YHG=3039>three" XBD=264 XHG=155 YBD=3119 YHG=3085>doses " XBD=332 XHG=290 YBD=3119 YHG=3085>of " XBD=494 XHG=358 YBD=3127 YHG=3087>10,000 " XBD=674 XHG=519 YBD=3121 YHG=3087>million " XBD=918 XHG=700 YBD=3132 YHG=3088>organisms " XBD=988 XHG=945 YBD=3121 YHG=3090>at " XBD=1206 XHG=1013 YBD=3121 YHG=3086>intervals " XBD=1277 XHG=1233 YBD=3122 YHG=3087>of " XBD=1334 XHG=1301 YBD=3128 YHG=3089>1," XBD=176 XHG=155 YBD=3166 YHG=3134>2 " XBD=330 XHG=204 YBD=3168 YHG=3135>and 5 " XBD=498 XHG=357 YBD=3176 YHG=3134>weeks, " XBD=608 XHG=528 YBD=3170 YHG=3136>and " XBD=693 XHG=638 YBD=3179 YHG=3137>(3) " XBD=746 XHG=723 YBD=3169 YHG=3147>a " XBD=923 XHG=775 YBD=3170 YHG=3135>similar " XBD=1113 XHG=950 YBD=3170 YHG=3137>vaccine " XBD=1337 XHG=1145 YBD=3180 YHG=3136>similarly" XBD=293 XHG=154 YBD=3225 YHG=3183>spaced " XBD=388 XHG=314 YBD=3217 YHG=3183>but " XBD=618 XHG=410 YBD=3218 YHG=3185>combined " XBD=739 XHG=640 YBD=3218 YHG=3185>with " XBD=988 XHG=761 YBD=3229 YHG=3184>diphtheria " XBD=1260 XHG=1010 YBD=3219 YHG=3185>toxoid-all " XBD=1334 XHG=1278 YBD=3217 YHG=3196>re-" XBD=281 XHG=156 YBD=3264 YHG=3230>sulted " XBD=346 XHG=305 YBD=3264 YHG=3231>in " XBD=390 XHG=367 YBD=3265 YHG=3243>a " XBD=522 XHG=404 YBD=3265 YHG=3232>much " XBD=663 XHG=544 YBD=3266 YHG=3232>lower " XBD=887 XHG=684 YBD=3266 YHG=3233>incidence " XBD=954 XHG=909 YBD=3266 YHG=3232>of " XBD=1176 XHG=972 YBD=3277 YHG=3233>pertussis, " XBD=1289 XHG=1192 YBD=3266 YHG=3233>with " XBD=1336 XHG=1312 YBD=3266 YHG=3244>a

" XBD=1277 XHG=1097 YBD=143 YHG=120>CONTROL " XBD=1358 XHG=1305 YBD=142 YHG=120>OF " XBD=1599 XHG=1387 YBD=144 YHG=119>PERTUSSIS

" XBD=576 XHG=342 YBD=446 YHG=364>THE " XBD=1164 XHG=654 YBD=444 YHG=370>LANCET" XBD=420 XHG=188 YBD=552 YHG=518>LONDON: |>|>" XBD=759 XHG=458 YBD=553 YHG=510>SATURDAY, |>" XBD=1084 XHG=792 YBD=547 YHG=513>FEBRUARY " XBD=1151 XHG=1117 YBD=551 YHG=514>5, " XBD=1276 XHG=1184 YBD=545 YHG=514>1944

1. Danghtry-Denmark, L. Amer. J. Dis. Child. 1942, 63, 453.2. Mishulow, L., Siegel, M., Leifer, L. and Berkey, S. R. Ibid, 1942,

63, 875.3. Flosdorf, E. W., Felton. H. M., Bondi, A. and McGuinness, A. C.

Amer. J. med. Sci. 1943, 206, 421.4. Kendrick, P. L. Amer. J. IIyg. 1943, 38, 193.

" XBD=1526 XHG=1381 YBD=248 YHG=198>higher " XBD=1779 XHG=1544 YBD=242 YHG=198>proportion " XBD=1842 XHG=1798 YBD=232 YHG=198>of " XBD=1953 XHG=1855 YBD=232 YHG=198>mild " XBD=2080 XHG=1972 YBD=232 YHG=209>cases " XBD=2243 XHG=2098 YBD=242 YHG=209>among " XBD=2334 XHG=2264 YBD=231 YHG=197>the " XBD=2584 XHG=2352 YBD=245 YHG=198>inoculated" XBD=1608 XHG=1381 YBD=290 YHG=245>compared " XBD=1725 XHG=1628 YBD=280 YHG=245>with " XBD=1960 XHG=1746 YBD=280 YHG=247>untreated " XBD=2156 XHG=1983 YBD=280 YHG=246>controls " XBD=2222 XHG=2177 YBD=280 YHG=245>of " XBD=2389 XHG=2240 YBD=279 YHG=245>similar " XBD=2485 XHG=2410 YBD=290 YHG=242>age " XBD=2584 XHG=2504 YBD=280 YHG=247>and" XBD=1564 XHG=1395 YBD=328 YHG=297>status.. " XBD=1678 XHG=1594 YBD=327 YHG=294>The " XBD=1872 XHG=1704 YBD=328 YHG=293>families " XBD=1939 XHG=1898 YBD=328 YHG=294>in " XBD=2039 XHG=1970 YBD=329 YHG=294>the " XBD=2222 XHG=2065 YBD=328 YHG=294>treated " XBD=2371 XHG=2253 YBD=328 YHG=294>series " XBD=2586 XHG=2402 YBD=327 YHG=293>however" XBD=1493 XHG=1392 YBD=376 YHG=353>were " XBD=1559 XHG=1506 YBD=376 YHG=354>on " XBD=1642 XHG=1571 YBD=376 YHG=342>the " XBD=1823 XHG=1654 YBD=387 YHG=354>average " XBD=1995 XHG=1837 YBD=377 YHG=342>smaller " XBD=2107 XHG=2007 YBD=377 YHG=343>than " XBD=2162 XHG=2119 YBD=376 YHG=343>in " XBD=2243 XHG=2173 YBD=377 YHG=343>the " XBD=2411 XHG=2257 YBD=376 YHG=341>control |>" XBD=2584 XHG=2423 YBD=387 YHG=352>groups," XBD=1520 XHG=1390 YBD=425 YHG=390>which " XBD=1680 XHG=1541 YBD=425 YHG=394>meant " XBD=1776 XHG=1700 YBD=425 YHG=390>less " XBD=2062 XHG=1797 YBD=436 YHG=391>opportunity " XBD=2144 XHG=2082 YBD=426 YHG=392>for " XBD=2352 XHG=2164 YBD=425 YHG=391>intimate " XBD=2582 XHG=2373 YBD=436 YHG=402>exposure." XBD=1519 XHG=1389 YBD=475 YHG=439>When " XBD=1757 XHG=1535 YBD=474 YHG=439>household " XBD=1989 XHG=1775 YBD=485 YHG=451>exposures " XBD=2105 XHG=2005 YBD=474 YHG=451>were " XBD=2314 XHG=2122 YBD=485 YHG=440>analysed " XBD=2364 XHG=2331 YBD=474 YHG=440>it " XBD=2583 XHG=2381 YBD=485 YHG=440>appeared" XBD=1483 XHG=1389 YBD=523 YHG=489>that " XBD=1681 XHG=1505 YBD=534 YHG=488>30-36% " XBD=1750 XHG=1706 YBD=523 YHG=488>of " XBD=1838 XHG=1767 YBD=523 YHG=488>the " XBD=2096 XHG=1858 YBD=523 YHG=489>vaccinated " XBD=2295 XHG=2118 YBD=523 YHG=489>children " XBD=2397 XHG=2317 YBD=524 YHG=489>and " XBD=2517 XHG=2418 YBD=535 YHG=488>92% " XBD=2587 XHG=2542 YBD=523 YHG=488>of" XBD=1460 XHG=1390 YBD=572 YHG=537>the " XBD=1788 XHG=1492 YBD=572 YHG=538>unvaccinated " XBD=1982 XHG=1819 YBD=573 YHG=537>became " XBD=2200 XHG=2013 YBD=573 YHG=537>infected. " XBD=2349 XHG=2253 YBD=573 YHG=538>This " XBD=2511 XHG=2379 YBD=573 YHG=537>factor " XBD=2589 XHG=2543 YBD=573 YHG=537>of" XBD=1578 XHG=1390 YBD=621 YHG=587>intimate " XBD=1802 XHG=1606 YBD=632 YHG=598>exposure " XBD=2014 XHG=1829 YBD=632 YHG=586>together " XBD=2137 XHG=2040 YBD=621 YHG=587>with " XBD=2409 XHG=2165 YBD=632 YHG=587>inadequate " XBD=2584 XHG=2437 YBD=633 YHG=587>dosage" XBD=1437 XHG=1392 YBD=670 YHG=635>of " XBD=1474 XHG=1450 YBD=670 YHG=647>a " XBD=1664 XHG=1492 YBD=681 YHG=635>straight " XBD=1844 XHG=1681 YBD=670 YHG=637>vaccine " XBD=1956 XHG=1860 YBD=681 YHG=648>may " XBD=2133 XHG=1972 YBD=681 YHG=635>explain " XBD=2219 XHG=2149 YBD=670 YHG=636>the " XBD=2422 XHG=2235 YBD=681 YHG=637>negative " XBD=2584 XHG=2438 YBD=671 YHG=636>results" XBD=1585 XHG=1393 YBD=720 YHG=685>obtained " XBD=1668 XHG=1612 YBD=730 YHG=685>by " XBD=1935 XHG=1693 YBD=720 YHG=679>McFARLAN " XBD=2043 XHG=1963 YBD=719 YHG=685>and " XBD=2240 XHG=2069 YBD=719 YHG=681>TOPLEY " XBD=2267 XHG=2253 YBD=707 YHG=689>5 " XBD=2337 XHG=2294 YBD=719 YHG=685>in " XBD=2388 XHG=2364 YBD=719 YHG=697>a " XBD=2583 XHG=2414 YBD=731 YHG=696>nursery" XBD=1522 XHG=1392 YBD=769 YHG=735>where " XBD=1581 XHG=1537 YBD=769 YHG=735>12 " XBD=1790 XHG=1600 YBD=776 YHG=733>children, " XBD=1932 XHG=1813 YBD=780 YHG=735>given " XBD=2026 XHG=1946 YBD=770 YHG=738>two " XBD=2156 XHG=2041 YBD=769 YHG=734>doses " XBD=2215 XHG=2171 YBD=769 YHG=734>of " XBD=2256 XHG=2232 YBD=770 YHG=747>a " XBD=2412 XHG=2272 YBD=776 YHG=736>20,000 " XBD=2582 XHG=2426 YBD=770 YHG=734>million" XBD=1613 XHG=1393 YBD=830 YHG=785>organisms " XBD=1790 XHG=1626 YBD=819 YHG=785>vaccine " XBD=1900 XHG=1802 YBD=818 YHG=784>with " XBD=1937 XHG=1913 YBD=818 YHG=785>4 " XBD=2078 XHG=1948 YBD=818 YHG=784>weeks " XBD=2281 XHG=2091 YBD=826 YHG=784>between, " XBD=2351 XHG=2296 YBD=818 YHG=783>all " XBD=2584 XHG=2362 YBD=829 YHG=784>developed" XBD=1586 XHG=1392 YBD=879 YHG=829>pertussis " XBD=1678 XHG=1604 YBD=868 YHG=837>not " XBD=1883 XHG=1697 YBD=868 YHG=833>different " XBD=1943 XHG=1900 YBD=867 YHG=833>in " XBD=2138 XHG=1963 YBD=878 YHG=833>severity " XBD=2200 XHG=2157 YBD=867 YHG=844>or " XBD=2318 XHG=2218 YBD=867 YHG=833>time " XBD=2382 XHG=2337 YBD=867 YHG=833>of " XBD=2583 XHG=2397 YBD=878 YHG=833>develop-" XBD=1503 XHG=1391 YBD=918 YHG=886>ment " XBD=1623 XHG=1518 YBD=918 YHG=882>from " XBD=1710 XHG=1638 YBD=918 YHG=883>the " XBD=1919 XHG=1725 YBD=917 YHG=881>infection " XBD=2079 XHG=1933 YBD=928 YHG=880>among " XBD=2143 XHG=2098 YBD=917 YHG=883>12 " XBD=2375 XHG=2160 YBD=917 YHG=882>untreated " XBD=2581 XHG=2391 YBD=917 YHG=882>children." XBD=1455 XHG=1391 YBD=967 YHG=933>An " XBD=1869 XHG=1473 YBD=978 YHG=931>alum-precipitated " XBD=2079 XHG=1885 YBD=977 YHG=932>pertussis " XBD=2178 XHG=2097 YBD=966 YHG=931>and " XBD=2425 XHG=2195 YBD=977 YHG=931>diphtheria " XBD=2585 XHG=2442 YBD=967 YHG=932>toxoid" XBD=1567 XHG=1391 YBD=1017 YHG=983>mixture " XBD=1659 XHG=1584 YBD=1017 YHG=982>has " XBD=1797 XHG=1676 YBD=1017 YHG=982>much " XBD=1859 XHG=1816 YBD=1017 YHG=984>to " XBD=2131 XHG=1878 YBD=1017 YHG=981>recommend " XBD=2184 XHG=2150 YBD=1016 YHG=981>it " XBD=2582 XHG=2202 YBD=1026 YHG=980>administratively,|>" XBD=1474 XHG=1374 YBD=1066 YHG=1032>and " XBD=1686 XHG=1494 YBD=1069 YHG=1031>ScHtiTZB " XBD=1716 XHG=1701 YBD=1054 YHG=1035>6 " XBD=1809 XHG=1735 YBD=1066 YHG=1031>has " XBD=1966 XHG=1828 YBD=1066 YHG=1031>shown " XBD=2078 XHG=1985 YBD=1066 YHG=1031>that " XBD=2195 XHG=2098 YBD=1066 YHG=1030>such " XBD=2247 XHG=2223 YBD=1066 YHG=1043>a " XBD=2449 XHG=2273 YBD=1066 YHG=1030>mixture " XBD=2512 XHG=2468 YBD=1065 YHG=1031>in " XBD=2584 XHG=2530 YBD=1065 YHG=1042>no" XBD=1482 XHG=1392 YBD=1126 YHG=1092>way " XBD=1708 XHG=1500 YBD=1116 YHG=1080>interferes " XBD=1820 XHG=1722 YBD=1116 YHG=1080>with " XBD=1904 XHG=1833 YBD=1116 YHG=1080>the " XBD=2183 XHG=1920 YBD=1126 YHG=1080>antigenicity " XBD=2242 XHG=2197 YBD=1115 YHG=1080>of " XBD=2379 XHG=2252 YBD=1115 YHG=1080>either " XBD=2585 XHG=2395 YBD=1126 YHG=1085>reagent;" XBD=1469 XHG=1394 YBD=1165 YHG=1130>but " XBD=1522 XHG=1489 YBD=1165 YHG=1130>it " XBD=1660 XHG=1542 YBD=1165 YHG=1133>must " XBD=1723 XHG=1673 YBD=1165 YHG=1130>be " XBD=1866 XHG=1743 YBD=1165 YHG=1131>borne " XBD=1929 XHG=1886 YBD=1164 YHG=1131>in " XBD=2061 XHG=1947 YBD=1165 YHG=1130>mind " XBD=2174 XHG=2081 YBD=1165 YHG=1130>that " XBD=2264 XHG=2193 YBD=1165 YHG=1130>the " XBD=2357 XHG=2284 YBD=1175 YHG=1141>age " XBD=2423 XHG=2377 YBD=1164 YHG=1129>of " XBD=2587 XHG=2446 YBD=1165 YHG=1130>attack" XBD=1424 XHG=1390 YBD=1214 YHG=1180>is " XBD=1623 XHG=1436 YBD=1214 YHG=1180>different " XBD=1678 XHG=1635 YBD=1214 YHG=1180>in " XBD=1759 XHG=1688 YBD=1214 YHG=1179>the " XBD=1851 XHG=1771 YBD=1214 YHG=1183>two " XBD=2075 XHG=1863 YBD=1214 YHG=1179>infections " XBD=2168 XHG=2088 YBD=1214 YHG=1179>and " XBD=2272 XHG=2179 YBD=1214 YHG=1179>that " XBD=2588 XHG=2283 YBD=1214 YHG=1179>immunisation

" XBD=1552 XHG=1393 YBD=1274 YHG=1229>against " XBD=1765 XHG=1571 YBD=1275 YHG=1229>pertussis " XBD=1931 XHG=1788 YBD=1264 YHG=1229>should " XBD=2070 XHG=1951 YBD=1274 YHG=1229>begin " XBD=2134 XHG=2090 YBD=1264 YHG=1232>at " XBD=2229 XHG=2155 YBD=1265 YHG=1230>3-6 " XBD=2413 XHG=2249 YBD=1264 YHG=1229>months " XBD=2481 XHG=2435 YBD=1263 YHG=1228>of " XBD=2583 XHG=2497 YBD=1274 YHG=1240>age.LAPIN " XBD=1657 XHG=1543 YBD=1313 YHG=1278>7 has " XBD=1870 XHG=1684 YBD=1324 YHG=1278>disposed " XBD=1943 XHG=1898 YBD=1313 YHG=1278>of " XBD=2041 XHG=1966 YBD=1314 YHG=1290>one " XBD=2175 XHG=2068 YBD=1325 YHG=1279>bogy " XBD=2256 XHG=2200 YBD=1324 YHG=1279>by " XBD=2461 XHG=2283 YBD=1324 YHG=1274>showing " XBD=2583 XHG=2488 YBD=1313 YHG=1279>that

" XBD=1546 XHG=1393 YBD=1362 YHG=1327>infants " XBD=1621 XHG=1554 YBD=1362 YHG=1339>are " XBD=1869 XHG=1628 YBD=1373 YHG=1327>apparently " XBD=2205 XHG=1876 YBD=1363 YHG=1328>as immunisable " XBD=2259 XHG=2216 YBD=1363 YHG=1340>as " XBD=2381 XHG=2272 YBD=1363 YHG=1328>older " XBD=2586 XHG=2394 YBD=1369 YHG=1327>children," XBD=1509 XHG=1393 YBD=1411 YHG=1376>while " XBD=1773 XHG=1528 YBD=1412 YHG=1376>BousplELD " XBD=1802 XHG=1789 YBD=1399 YHG=1380>s " XBD=1894 XHG=1821 YBD=1411 YHG=1377>has " XBD=2042 XHG=1912 YBD=1411 YHG=1377>raised " XBD=2229 XHG=2060 YBD=1412 YHG=1377>another " XBD=2289 XHG=2247 YBD=1411 YHG=1377>in " XBD=2491 XHG=2307 YBD=1422 YHG=1377>pointing " XBD=2584 XHG=2512 YBD=1412 YHG=1381>out" XBD=1487 XHG=1393 YBD=1461 YHG=1426>that " XBD=1533 XHG=1509 YBD=1460 YHG=1437>a " XBD=1788 XHG=1553 YBD=1471 YHG=1425>phenolised " XBD=2001 XHG=1809 YBD=1472 YHG=1426>pertussis " XBD=2185 XHG=2021 YBD=1462 YHG=1427>vaccine " XBD=2341 XHG=2205 YBD=1461 YHG=1426>mixed " XBD=2461 XHG=2362 YBD=1462 YHG=1427>with " XBD=2587 XHG=2482 YBD=1461 YHG=1427>APT" XBD=1436 XHG=1393 YBD=1510 YHG=1476>in " XBD=1527 XHG=1457 YBD=1510 YHG=1475>the " XBD=1708 XHG=1549 YBD=1521 YHG=1475>syringe " XBD=1824 XHG=1728 YBD=1521 YHG=1487>may " XBD=2029 XHG=1842 YBD=1510 YHG=1475>interfere " XBD=2148 XHG=2050 YBD=1511 YHG=1475>with " XBD=2239 XHG=2168 YBD=1510 YHG=1475>the " XBD=2525 XHG=2260 YBD=1521 YHG=1476>antigenicity " XBD=2592 XHG=2546 YBD=1511 YHG=1476>of" XBD=1464 XHG=1394 YBD=1559 YHG=1525>the " XBD=1653 XHG=1485 YBD=1565 YHG=1524>toxoid ; " XBD=1740 XHG=1690 YBD=1559 YHG=1524>he " XBD=2034 XHG=1760 YBD=1559 YHG=1524>recommends " XBD=2237 XHG=2055 YBD=1570 YHG=1528>separate " XBD=2469 XHG=2256 YBD=1569 YHG=1524>injections " XBD=2589 XHG=2490 YBD=1560 YHG=1525>with" XBD=1579 XHG=1396 YBD=1619 YHG=1577>separate " XBD=1778 XHG=1600 YBD=1619 YHG=1573>syringes " XBD=1903 XHG=1799 YBD=1608 YHG=1572>until " XBD=2005 XHG=1923 YBD=1607 YHG=1573>this " XBD=2238 XHG=2024 YBD=1609 YHG=1573>drawback " XBD=2330 XHG=2257 YBD=1608 YHG=1574>has " XBD=2452 XHG=2350 YBD=1609 YHG=1574>been " XBD=2584 XHG=2473 YBD=1609 YHG=1585>over-" XBD=1518 XHG=1396 YBD=1660 YHG=1634>come. " XBD=1610 XHG=1573 YBD=1657 YHG=1623>A " XBD=1820 XHG=1633 YBD=1668 YHG=1623>boosting " XBD=1946 XHG=1852 YBD=1657 YHG=1623>dose " XBD=1993 XHG=1971 YBD=1657 YHG=1623>2 " XBD=2140 XHG=2025 YBD=1668 YHG=1634>years " XBD=2275 XHG=2172 YBD=1657 YHG=1623>after " XBD=2375 XHG=2304 YBD=1658 YHG=1623>the " XBD=2587 XHG=2406 YBD=1669 YHG=1623>primary" XBD=1644 XHG=1395 YBD=1707 YHG=1672>inoculation " XBD=1713 XHG=1669 YBD=1706 YHG=1683>or " XBD=1851 XHG=1736 YBD=1706 YHG=1672>when " XBD=1944 XHG=1874 YBD=1706 YHG=1671>the " XBD=2075 XHG=1969 YBD=1706 YHG=1671>child " XBD=2190 XHG=2098 YBD=1717 YHG=1684>goes " XBD=2258 XHG=2214 YBD=1707 YHG=1676>to " XBD=2418 XHG=2283 YBD=1707 YHG=1672>school " XBD=2588 XHG=2443 YBD=1707 YHG=1672>should" XBD=1571 XHG=1395 YBD=1757 YHG=1722>increase " XBD=1813 XHG=1596 YBD=1756 YHG=1722>resistance " XBD=1916 XHG=1836 YBD=1756 YHG=1721>and " XBD=2030 XHG=1937 YBD=1766 YHG=1721>help " XBD=2097 XHG=2053 YBD=1756 YHG=1725>to " XBD=2321 XHG=2124 YBD=1757 YHG=1721>minimise " XBD=2417 XHG=2347 YBD=1756 YHG=1721>the " XBD=2522 XHG=2439 YBD=1756 YHG=1722>risk " XBD=2591 XHG=2545 YBD=1756 YHG=1722>of" XBD=1590 XHG=1396 YBD=1805 YHG=1770>infection " XBD=1742 XHG=1624 YBD=1816 YHG=1771>being " XBD=1949 XHG=1775 YBD=1816 YHG=1770>brought " XBD=2086 XHG=1982 YBD=1805 YHG=1770>from " XBD=2255 XHG=2120 YBD=1805 YHG=1771>school " XBD=2405 XHG=2287 YBD=1806 YHG=1771>home " XBD=2483 XHG=2438 YBD=1806 YHG=1774>to " XBD=2587 XHG=2517 YBD=1806 YHG=1772>the" XBD=1574 XHG=1395 YBD=1865 YHG=1832>younger " XBD=1791 XHG=1593 YBD=1854 YHG=1821>members " XBD=1856 XHG=1812 YBD=1854 YHG=1820>of " XBD=1942 XHG=1872 YBD=1855 YHG=1820>the " XBD=2114 XHG=1962 YBD=1865 YHG=1819>family. " XBD=2209 XHG=2168 YBD=1855 YHG=1821>It " XBD=2262 XHG=2229 YBD=1854 YHG=1820>is " XBD=2365 XHG=2283 YBD=1855 YHG=1820>still " XBD=2455 XHG=2384 YBD=1855 YHG=1823>too " XBD=2587 XHG=2476 YBD=1865 YHG=1821>early" XBD=1439 XHG=1395 YBD=1904 YHG=1873>to " XBD=1535 XHG=1461 YBD=1915 YHG=1881>say " XBD=1665 XHG=1555 YBD=1904 YHG=1869>what " XBD=1778 XHG=1686 YBD=1915 YHG=1873>part " XBD=1992 XHG=1799 YBD=1915 YHG=1870>pertussis " XBD=2128 XHG=2012 YBD=1904 YHG=1869>toxin " XBD=2264 XHG=2149 YBD=1915 YHG=1869>plays " XBD=2328 XHG=2285 YBD=1904 YHG=1870>in " XBD=2419 XHG=2348 YBD=1904 YHG=1869>the " XBD=2583 XHG=2439 YBD=1915 YHG=1869>patho-" XBD=1549 XHG=1396 YBD=1964 YHG=1919>genesis " XBD=1626 XHG=1581 YBD=1953 YHG=1918>of " XBD=1723 XHG=1652 YBD=1954 YHG=1919>the " XBD=1918 XHG=1754 YBD=1953 YHG=1919>disease. " XBD=2055 XHG=1972 YBD=1953 YHG=1919>The " XBD=2194 XHG=2086 YBD=1953 YHG=1919>work " XBD=2270 XHG=2225 YBD=1953 YHG=1918>of EVANS " XBD=2583 XHG=2456 YBD=1952 YHG=1919>9 and" XBD=1531 XHG=1396 YBD=2002 YHG=1968>others " XBD=1745 XHG=1549 YBD=2003 YHG=1968>indicates " XBD=1863 XHG=1771 YBD=2002 YHG=1968>that " XBD=1970 XHG=1888 YBD=2002 YHG=1968>this " XBD=2225 XHG=1994 YBD=2002 YHG=1967>heat-labile " XBD=2371 XHG=2244 YBD=2008 YHG=1968>toxin, " XBD=2589 XHG=2390 YBD=2002 YHG=1967>liberated" XBD=1453 XHG=1397 YBD=2062 YHG=2018>by " XBD=1697 XHG=1467 YBD=2062 YHG=2016>disrupting " XBD=1782 XHG=1712 YBD=2051 YHG=2017>the " XBD=2019 XHG=1799 YBD=2062 YHG=2017>organisms " XBD=2089 XHG=2033 YBD=2062 YHG=2017>by " XBD=2284 XHG=2103 YBD=2062 YHG=2016>physical " XBD=2497 XHG=2298 YBD=2058 YHG=2016>methods, " XBD=2588 XHG=2515 YBD=2050 YHG=2016>has" XBD=1521 XHG=1395 YBD=2101 YHG=2066>lethal " XBD=1615 XHG=1534 YBD=2101 YHG=2067>and " XBD=1869 XHG=1628 YBD=2112 YHG=2066>necrotising " XBD=2112 XHG=1881 YBD=2112 YHG=2067>properties, " XBD=2208 XHG=2128 YBD=2100 YHG=2066>and " XBD=2314 XHG=2220 YBD=2100 YHG=2066>that " XBD=2350 XHG=2327 YBD=2100 YHG=2077>a " XBD=2588 XHG=2363 YBD=2111 YHG=2066>protective" XBD=1601 XHG=1397 YBD=2150 YHG=2116>antitoxin " XBD=1699 XHG=1623 YBD=2150 YHG=2127>can " XBD=1769 XHG=1720 YBD=2151 YHG=2116>be " XBD=1984 XHG=1789 YBD=2162 YHG=2116>prepared " XBD=2336 XHG=2005 YBD=2162 YHG=2114>experimentally " XBD=2398 XHG=2355 YBD=2149 YHG=2115>in " XBD=2590 XHG=2419 YBD=2149 YHG=2114>animals" XBD=1453 XHG=1398 YBD=2209 YHG=2165>by " XBD=1538 XHG=1468 YBD=2199 YHG=2165>the " XBD=1747 XHG=1553 YBD=2210 YHG=2165>injection " XBD=1808 XHG=1762 YBD=2199 YHG=2164>of " XBD=1972 XHG=1819 YBD=2200 YHG=2166>toxoid. " XBD=2061 XHG=2025 YBD=2200 YHG=2166>A " XBD=2233 XHG=2077 YBD=2211 YHG=2165>specific " XBD=2466 XHG=2250 YBD=2206 YHG=2164>antitoxin, " XBD=2589 XHG=2483 YBD=2200 YHG=2164>how-" XBD=1501 XHG=1397 YBD=2257 YHG=2225>ever, " XBD=1608 XHG=1534 YBD=2248 YHG=2214>has " XBD=1713 XHG=1639 YBD=2248 YHG=2218>not " XBD=1845 XHG=1744 YBD=2248 YHG=2215>been " XBD=2181 XHG=1879 YBD=2249 YHG=2214>demonstrated " XBD=2257 XHG=2213 YBD=2248 YHG=2214>in " XBD=2361 XHG=2290 YBD=2248 YHG=2214>the " XBD=2515 XHG=2392 YBD=2248 YHG=2213>blood " XBD=2593 XHG=2547 YBD=2248 YHG=2213>of" XBD=1590 XHG=1396 YBD=2308 YHG=2264>pertussis " XBD=1823 XHG=1601 YBD=2307 YHG=2263>patients " XBD=1890 XHG=1854 YBD=2297 YHG=2264>A " XBD=2065 XHG=1901 YBD=2298 YHG=2264>vaccine " XBD=2308 XHG=2079 YBD=2308 YHG=2263>containing " XBD=2428 XHG=2327 YBD=2298 YHG=2263>both " XBD=2589 XHG=2446 YBD=2297 YHG=2262>toxoid" XBD=1480 XHG=1399 YBD=2346 YHG=2312>and " XBD=1637 XHG=1505 YBD=2346 YHG=2311>intact " XBD=1841 XHG=1664 YBD=2348 YHG=2312>bacteria " XBD=1970 XHG=1874 YBD=2357 YHG=2324>may " XBD=2117 XHG=1995 YBD=2357 YHG=2324>prove " XBD=2187 XHG=2144 YBD=2346 YHG=2315>to " XBD=2264 XHG=2214 YBD=2347 YHG=2312>be " XBD=2360 XHG=2289 YBD=2345 YHG=2312>the " XBD=2476 XHG=2386 YBD=2346 YHG=2312>best " XBD=2590 XHG=2502 YBD=2356 YHG=2322>pro-" XBD=1553 XHG=1397 YBD=2405 YHG=2361>tecting " XBD=2157 XHG=1572 YBD=2406 YHG=2364>agent." XBD=1563 XHG=1446 YBD=2452 YHG=2416>Until " XBD=1764 XHG=1578 YBD=2452 YHG=2418>vaccines " XBD=1847 XHG=1780 YBD=2452 YHG=2429>are " XBD=1972 XHG=1862 YBD=2452 YHG=2429>more " XBD=2307 XHG=1989 YBD=2452 YHG=2416>effective-and " XBD=2433 XHG=2322 YBD=2451 YHG=2428>more " XBD=2592 XHG=2448 YBD=2462 YHG=2416>plenti-" XBD=1469 XHG=1397 YBD=2508 YHG=2465>ful, " XBD=1563 XHG=1500 YBD=2501 YHG=2466>for " XBD=1638 XHG=1594 YBD=2501 YHG=2469>at " XBD=1830 XHG=1668 YBD=2511 YHG=2470>present " XBD=2035 XHG=1859 YBD=2501 YHG=2466>demand " XBD=2231 XHG=2066 YBD=2500 YHG=2465>exceeds " XBD=2422 XHG=2263 YBD=2511 YHG=2465>supply, " XBD=2591 XHG=2453 YBD=2511 YHG=2466>partly" XBD=1567 XHG=1397 YBD=2550 YHG=2515>because " XBD=1636 XHG=1590 YBD=2549 YHG=2515>of " XBD=1725 XHG=1654 YBD=2549 YHG=2515>the |>" XBD=1947 XHG=1748 YBD=2559 YHG=2515>difficulty " XBD=2015 XHG=1970 YBD=2549 YHG=2514>of " XBD=2303 XHG=2033 YBD=2560 YHG=2513>preparation, " XBD=2466 XHG=2327 YBD=2559 YHG=2514>partly " XBD=2592 XHG=2489 YBD=2549 YHG=2515>from" XBD=1468 XHG=1397 YBD=2598 YHG=2564>the " XBD=1650 XHG=1494 YBD=2609 YHG=2567>greater " XBD=1844 XHG=1677 YBD=2598 YHG=2564>interest " XBD=1913 XHG=1870 YBD=2597 YHG=2564>in " XBD=2362 XHG=1938 YBD=2608 YHG=2563>prophylaxis-more " XBD=2594 XHG=2389 YBD=2598 YHG=2564>attention" XBD=1543 XHG=1399 YBD=2648 YHG=2613>should " XBD=1615 XHG=1566 YBD=2647 YHG=2613>be " XBD=1758 XHG=1638 YBD=2658 YHG=2613>given " XBD=1824 XHG=1780 YBD=2647 YHG=2615>to " XBD=1988 XHG=1848 YBD=2647 YHG=2611>earlier " XBD=2223 XHG=2010 YBD=2657 YHG=2612>diagnosis. " XBD=2361 XHG=2276 YBD=2647 YHG=2612>The " XBD=2536 XHG=2384 YBD=2653 YHG=2612>disease |>" XBD=2594 XHG=2552 YBD=2647 YHG=2613>is" XBD=1488 XHG=1398 YBD=2696 YHG=2673>now " XBD=1710 XHG=1506 YBD=2706 YHG=2661>generally " XBD=1946 XHG=1728 YBD=2702 YHG=2661>notifiable, " XBD=2049 XHG=1968 YBD=2695 YHG=2661>and " XBD=2169 XHG=2068 YBD=2695 YHG=2661>both " XBD=2329 XHG=2188 YBD=2696 YHG=2661>doctor " XBD=2431 XHG=2349 YBD=2696 YHG=2662>and " XBD=2595 XHG=2449 YBD=2707 YHG=2665>parent" XBD=1544 XHG=1399 YBD=2744 YHG=2710>should " XBD=1611 XHG=1561 YBD=2744 YHG=2711>be " XBD=1879 XHG=1630 YBD=2754 YHG=2708>encouraged " XBD=1941 XHG=1897 YBD=2743 YHG=2712>to " XBD=2096 XHG=1959 YBD=2753 YHG=2712>report " XBD=2201 XHG=2113 YBD=2744 YHG=2709>first " XBD=2329 XHG=2220 YBD=2745 YHG=2721>cases " XBD=2389 XHG=2346 YBD=2744 YHG=2711>in " XBD=2432 XHG=2407 YBD=2744 YHG=2722>a " XBD=2590 XHG=2449 YBD=2745 YHG=2710>house-" XBD=1495 XHG=1398 YBD=2793 YHG=2758>hold " XBD=1568 XHG=1523 YBD=2793 YHG=2769>as " XBD=1710 XHG=1597 YBD=2802 YHG=2757>early " XBD=1782 XHG=1738 YBD=2792 YHG=2769>as " XBD=1983 XHG=1810 YBD=2803 YHG=2757>possible " XBD=2056 XHG=2012 YBD=2792 YHG=2769>so " XBD=2178 XHG=2086 YBD=2793 YHG=2759>that " XBD=2408 XHG=2205 YBD=2794 YHG=2770>measures " XBD=2514 XHG=2439 YBD=2794 YHG=2770>can " XBD=2593 XHG=2543 YBD=2794 YHG=2759>be" XBD=1523 XHG=1398 YBD=2841 YHG=2807>taken " XBD=1581 XHG=1537 YBD=2841 YHG=2810>to " XBD=1755 XHG=1595 YBD=2852 YHG=2807>protect " XBD=1897 XHG=1770 YBD=2848 YHG=2807>other, " XBD=2174 XHG=1912 YBD=2852 YHG=2806>particularly " XBD=2379 XHG=2188 YBD=2853 YHG=2819>younger, " XBD=2593 XHG=2394 YBD=2843 YHG=2810>members" XBD=1445 XHG=1399 YBD=2891 YHG=2855>of " XBD=1540 XHG=1469 YBD=2890 YHG=2855>the " XBD=1722 XHG=1567 YBD=2901 YHG=2855>family. " XBD=1820 XHG=1776 YBD=2889 YHG=2855>If " XBD=2104 XHG=1842 YBD=2900 YHG=2856>satisfactory " XBD=2431 XHG=2130 YBD=2903 YHG=2856>home-nursing " XBD=2493 XHG=2459 YBD=2892 YHG=2858>is " XBD=2596 XHG=2521 YBD=2891 YHG=2861>not" XBD=1573 XHG=1398 YBD=2950 YHG=2904>possible " XBD=1660 XHG=1588 YBD=2939 YHG=2904>the " XBD=1785 XHG=1678 YBD=2938 YHG=2904>child " XBD=1945 XHG=1801 YBD=2939 YHG=2904>should " XBD=2012 XHG=1962 YBD=2939 YHG=2905>be " XBD=2228 XHG=2027 YBD=2940 YHG=2905>admitted " XBD=2288 XHG=2244 YBD=2940 YHG=2909>to " XBD=2493 XHG=2305 YBD=2951 YHG=2906>hospital, " XBD=2594 XHG=2513 YBD=2940 YHG=2906>and" XBD=1596 XHG=1399 YBD=2998 YHG=2953>hospitals " XBD=1718 XHG=1607 YBD=2987 YHG=2957>must " XBD=1897 XHG=1731 YBD=2998 YHG=2953>provide " XBD=2019 XHG=1910 YBD=2988 YHG=2965>more |>" XBD=2217 XHG=2032 YBD=2988 YHG=2953>facilities " XBD=2292 XHG=2229 YBD=2989 YHG=2955>for " XBD=2483 XHG=2304 YBD=2999 YHG=2956>patients " XBD=2595 XHG=2496 YBD=2988 YHG=2955>with" XBD=1605 XHG=1383 YBD=3047 YHG=3003>,pertussis, " XBD=1757 XHG=1627 YBD=3036 YHG=3002>which " XBD=1915 XHG=1776 YBD=3036 YHG=3013>means " XBD=2007 XHG=1934 YBD=3037 YHG=3005>not " XBD=2123 XHG=2027 YBD=3048 YHG=3003>only " XBD=2250 XHG=2140 YBD=3037 YHG=3014>more " XBD=2369 XHG=2270 YBD=3038 YHG=3004>beds " XBD=2464 XHG=2388 YBD=3037 YHG=3003>but " XBD=2594 XHG=2483 YBD=3037 YHG=3014>more" XBD=1501 XHG=1399 YBD=3084 YHG=3051>than " XBD=1593 XHG=1522 YBD=3085 YHG=3051>the " XBD=1788 XHG=1616 YBD=3096 YHG=3062>average " XBD=1982 XHG=1808 YBD=3085 YHG=3049>ratio of " XBD=2138 XHG=1999 YBD=3085 YHG=3062>nurses " XBD=2204 XHG=2160 YBD=3085 YHG=3054>to " XBD=2405 XHG=2225 YBD=3097 YHG=3052>patients " XBD=2463 XHG=2428 YBD=3085 YHG=3051>if " XBD=2595 XHG=2481 YBD=3085 YHG=3051>these" XBD=1580 XHG=1402 YBD=3133 YHG=3099>children " XBD=1677 XHG=1609 YBD=3132 YHG=3110>are " XBD=1749 XHG=1705 YBD=3133 YHG=3102>to " XBD=1828 XHG=1778 YBD=3134 YHG=3099>be " XBD=2044 XHG=1856 YBD=3145 YHG=3098>properly " XBD=2229 XHG=2071 YBD=3136 YHG=3100>nursed. " XBD=2374 XHG=2288 YBD=3135 YHG=3099>The " XBD=2501 XHG=2394 YBD=3133 YHG=3099>child " XBD=2592 XHG=2518 YBD=3132 YHG=3099>has" XBD=1561 XHG=1401 YBD=3192 YHG=3146>usually " XBD=1716 XHG=1575 YBD=3182 YHG=3148>ceased " XBD=1773 XHG=1729 YBD=3182 YHG=3152>to " XBD=1836 XHG=1786 YBD=3182 YHG=3148>be " XBD=2062 XHG=1848 YBD=3183 YHG=3148>infectious " XBD=2130 XHG=2075 YBD=3193 YHG=3148>by " XBD=2212 XHG=2143 YBD=3182 YHG=3148>the " XBD=2305 XHG=2227 YBD=3182 YHG=3148>end " XBD=2364 XHG=2319 YBD=3182 YHG=3147>of " XBD=2443 XHG=2372 YBD=3182 YHG=3147>the " XBD=2595 XHG=2456 YBD=3181 YHG=3147>fourth" XBD=1521 XHG=1401 YBD=3237 YHG=3197>week, " XBD=1624 XHG=1543 YBD=3233 YHG=3196>and " XBD=1677 XHG=1641 YBD=3229 YHG=3196>if " XBD=1900 XHG=1692 YBD=3231 YHG=3196>otherwise " XBD=2005 XHG=1917 YBD=3230 YHG=3196>well " XBD=2116 XHG=2021 YBD=3240 YHG=3208>may " XBD=2183 XHG=2134 YBD=3230 YHG=3196>be " XBD=2446 XHG=2211 YBD=3240 YHG=3195>discharged " XBD=2613 XHG=2463 YBD=3240 YHG=3196>home,.

5. McFarlan, A. M. and Topley, E. Mon. Bull. Min. Hlth, November,1943, p. 122.

6. Schütze, H. Lancet, 1940, ii, 192.7. Lapin, J. H. Amer. J. Dis. Child. 1942, 63, 225. 8. Bousfield, G. Med. Off. Nov. 13, 1943, p. 159.9. Evans, D. G. Lancet, 1942, i, 529.

10. Evans, D. G. and Maitland, H. R. J. Path. Bact. 1939, 48, 465.

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" XBD=346 XHG=191 YBD=236 YHG=191>though " XBD=462 XHG=382 YBD=225 YHG=191>still " XBD=722 XHG=497 YBD=235 YHG=192>whooping. " XBD=1092 XHG=776 YBD=235 YHG=189>Unfortunately " XBD=1318 XHG=1126 YBD=236 YHG=191>pertussis " XBD=1386 XHG=1352 YBD=225 YHG=191>is" XBD=392 XHG=192 YBD=284 YHG=239>clinically " XBD=444 XHG=420 YBD=273 YHG=251>a " XBD=645 XHG=474 YBD=273 YHG=239>difficult " XBD=827 XHG=675 YBD=272 YHG=240>disease " XBD=901 XHG=857 YBD=273 YHG=242>to " XBD=1119 XHG=931 YBD=283 YHG=239>diagnose " XBD=1271 XHG=1149 YBD=285 YHG=239>early, " XBD=1385 XHG=1303 YBD=273 YHG=240>and" XBD=385 XHG=192 YBD=333 YHG=288>ancillary " XBD=653 XHG=418 YBD=332 YHG=288>laboratory " XBD=774 XHG=687 YBD=321 YHG=288>aids " XBD=970 XHG=808 YBD=322 YHG=288>become " XBD=1202 XHG=1004 YBD=322 YHG=288>essential. " XBD=1384 XHG=1257 YBD=322 YHG=288>There" XBD=224 XHG=190 YBD=371 YHG=338>is " XBD=353 XHG=245 YBD=371 YHG=349>some " XBD=563 XHG=374 YBD=370 YHG=337>evidence " XBD=671 XHG=578 YBD=371 YHG=336>that " XBD=755 XHG=685 YBD=370 YHG=336>the " XBD=1066 XHG=771 YBD=371 YHG=337>characteristic " XBD=1232 XHG=1082 YBD=382 YHG=337>change " XBD=1292 XHG=1250 YBD=371 YHG=338>in " XBD=1383 XHG=1312 YBD=372 YHG=337>the" XBD=486 XHG=192 YBD=430 YHG=386>blood-picture " XBD=660 XHG=522 YBD=419 YHG=396>occurs " XBD=848 XHG=696 YBD=430 YHG=385>early,&dquo; " XBD=1054 XHG=884 YBD=431 YHG=386>perhaps " XBD=1190 XHG=1090 YBD=421 YHG=398>even " XBD=1272 XHG=1229 YBD=420 YHG=387>in " XBD=1381 XHG=1307 YBD=420 YHG=387>the" XBD=425 XHG=190 YBD=469 YHG=435>incubation " XBD=593 XHG=442 YBD=478 YHG=434>period, " XBD=695 XHG=614 YBD=468 YHG=434>and " XBD=736 XHG=713 YBD=468 YHG=446>a " XBD=1070 XHG=754 YBD=479 YHG=434>lymphocytosis " XBD=1133 XHG=1089 YBD=469 YHG=435>of " XBD=1321 XHG=1147 YBD=480 YHG=435>60-80% " XBD=1383 XHG=1341 YBD=468 YHG=435>in" XBD=214 XHG=190 YBD=517 YHG=495>a " XBD=340 XHG=234 YBD=516 YHG=483>child " XBD=455 XHG=357 YBD=516 YHG=483>with " XBD=498 XHG=474 YBD=516 YHG=493>a " XBD=738 XHG=517 YBD=526 YHG=483>suspicious " XBD=886 XHG=758 YBD=528 YHG=484>cough " XBD=999 XHG=903 YBD=528 YHG=496>may " XBD=1065 XHG=1016 YBD=518 YHG=484>be " XBD=1186 XHG=1082 YBD=528 YHG=484>good " XBD=1380 XHG=1205 YBD=529 YHG=484>grounds" XBD=251 XHG=189 YBD=565 YHG=531>for " XBD=528 XHG=276 YBD=565 YHG=531>notification " XBD=636 XHG=554 YBD=565 YHG=532>and " XBD=859 XHG=659 YBD=566 YHG=531>isolation. " XBD=996 XHG=913 YBD=566 YHG=533>The " XBD=1219 XHG=1021 YBD=578 YHG=532>difficulty " XBD=1285 XHG=1243 YBD=566 YHG=533>in " XBD=1380 XHG=1310 YBD=566 YHG=532>the" XBD=378 XHG=189 YBD=615 YHG=580>isolation " XBD=443 XHG=398 YBD=615 YHG=579>of " XBD=512 XHG=458 YBD=614 YHG=581>H. " XBD=723 XHG=531 YBD=625 YHG=581>pertussis " XBD=799 XHG=744 YBD=626 YHG=581>by " XBD=889 XHG=819 YBD=616 YHG=581>the " XBD=1038 XHG=911 YBD=627 YHG=582>cough " XBD=1167 XHG=1058 YBD=627 YHG=582>plate " XBD=1315 XHG=1189 YBD=616 YHG=593>seems " XBD=1379 XHG=1336 YBD=615 YHG=584>to" XBD=306 XHG=187 YBD=665 YHG=630>make " XBD=400 XHG=319 YBD=663 YHG=630>this " XBD=580 XHG=412 YBD=664 YHG=630>method " XBD=838 XHG=593 YBD=675 YHG=631>practicable " XBD=954 XHG=859 YBD=676 YHG=631>only " XBD=1008 XHG=965 YBD=665 YHG=631>in " XBD=1207 XHG=1019 YBD=676 YHG=631>hospital, " XBD=1376 XHG=1222 YBD=675 YHG=631>though" XBD=258 XHG=188 YBD=713 YHG=679>the " XBD=415 XHG=280 YBD=713 YHG=680>Danes " XBD=541 XHG=436 YBD=713 YHG=679>have " XBD=661 XHG=562 YBD=713 YHG=679>used " XBD=716 XHG=683 YBD=714 YHG=680>it " XBD=780 XHG=737 YBD=713 YHG=680>in " XBD=1051 XHG=802 YBD=725 YHG=677>domiciliary " XBD=1259 XHG=1071 YBD=725 YHG=680>practice. " XBD=1377 XHG=1315 YBD=714 YHG=679>On" XBD=357 XHG=188 YBD=762 YHG=729>another " XBD=474 XHG=373 YBD=773 YHG=739>page " XBD=798 XHG=490 YBD=763 YHG=728>CRUICKSHANK " XBD=968 XHG=813 YBD=774 YHG=732>reports " XBD=1219 XHG=984 YBD=763 YHG=719>favourable " XBD=1379 XHG=1234 YBD=762 YHG=728>results" XBD=286 XHG=188 YBD=812 YHG=777>with " XBD=384 XHG=313 YBD=811 YHG=777>the " XBD=619 XHG=410 YBD=822 YHG=777>postnasal " XBD=755 XHG=647 YBD=812 YHG=778>swab " XBD=908 XHG=783 YBD=812 YHG=778>taken " XBD=1109 XHG=934 YBD=822 YHG=777>through " XBD=1207 XHG=1136 YBD=811 YHG=777>the " XBD=1377 XHG=1233 YBD=811 YHG=777>mouth" XBD=269 XHG=187 YBD=861 YHG=827>and " XBD=528 XHG=297 YBD=861 YHG=826>inoculated " XBD=609 XHG=556 YBD=861 YHG=838>on " XBD=974 XHG=637 YBD=871 YHG=826>Bordet-Gengou " XBD=1177 XHG=1001 YBD=860 YHG=826>medium " XBD=1375 XHG=1206 YBD=871 YHG=822>im’preg-" XBD=312 XHG=187 YBD=910 YHG=875>nated " XBD=436 XHG=337 YBD=909 YHG=875>with " XBD=679 XHG=463 YBD=920 YHG=875>penicillin, " XBD=836 XHG=708 YBD=909 YHG=875>which " XBD=1030 XHG=863 YBD=909 YHG=875>inhibits " XBD=1127 XHG=1057 YBD=909 YHG=875>the " XBD=1307 XHG=1154 YBD=920 YHG=874>growth " XBD=1381 XHG=1336 YBD=908 YHG=874>of" XBD=302 XHG=187 YBD=958 YHG=924>other " XBD=504 XHG=326 YBD=959 YHG=925>bacteria " XBD=638 XHG=528 YBD=959 YHG=936>more " XBD=765 XHG=663 YBD=959 YHG=925>than " XBD=842 XHG=789 YBD=959 YHG=924>H. " XBD=1069 XHG=864 YBD=969 YHG=924>pertussis. " XBD=1207 XHG=1123 YBD=958 YHG=924>The " XBD=1376 XHG=1231 YBD=969 YHG=924>practi-" XBD=316 XHG=185 YBD=1009 YHG=974>tioner " XBD=456 XHG=338 YBD=1009 YHG=974>could " XBD=631 XHG=475 YBD=1019 YHG=973>readily " XBD=721 XHG=651 YBD=1008 YHG=986>use " XBD=840 XHG=742 YBD=1008 YHG=974>such " XBD=885 XHG=861 YBD=1008 YHG=986>a " XBD=1071 XHG=904 YBD=1008 YHG=973>method " XBD=1153 XHG=1091 YBD=1008 YHG=973>for " XBD=1377 XHG=1173 YBD=1018 YHG=973>detecting" XBD=296 XHG=185 YBD=1068 YHG=1023>early " XBD=450 XHG=329 YBD=1064 YHG=1035>cases, " XBD=568 XHG=486 YBD=1057 YHG=1023>and " XBD=653 XHG=600 YBD=1057 YHG=1035>no " XBD=816 XHG=687 YBD=1057 YHG=1023>doubt " XBD=980 XHG=848 YBD=1057 YHG=1022>would " XBD=1149 XHG=1013 YBD=1067 YHG=1022>gladly " XBD=1234 XHG=1182 YBD=1056 YHG=1022>do " XBD=1311 XHG=1269 YBD=1056 YHG=1034>so " XBD=1381 XHG=1345 YBD=1055 YHG=1022>if" XBD=418 XHG=184 YBD=1117 YHG=1072>laboratory " XBD=615 XHG=428 YBD=1106 YHG=1072>facilities " XBD=727 XHG=627 YBD=1107 YHG=1083>were " XBD=948 XHG=740 YBD=1106 YHG=1071>available. " XBD=1192 XHG=981 YBD=1106 YHG=1071>American " XBD=1376 XHG=1204 YBD=1106 YHG=1071>workers" XBD=288 XHG=183 YBD=1157 YHG=1122>have " XBD=489 XHG=302 YBD=1167 YHG=1122>reported " XBD=608 XHG=503 YBD=1167 YHG=1122>good " XBD=779 XHG=622 YBD=1163 YHG=1121>results, " XBD=1056 XHG=795 YBD=1167 YHG=1120>particularly " XBD=1111 XHG=1069 YBD=1155 YHG=1121>in " XBD=1237 XHG=1127 YBD=1166 YHG=1121>early " XBD=1374 XHG=1253 YBD=1163 YHG=1133>cases," XBD=286 XHG=184 YBD=1205 YHG=1171>from " XBD=378 XHG=307 YBD=1205 YHG=1171>the " XBD=467 XHG=397 YBD=1205 YHG=1182>use " XBD=533 XHG=487 YBD=1205 YHG=1170>of " XBD=573 XHG=548 YBD=1205 YHG=1182>a " XBD=674 XHG=592 YBD=1205 YHG=1170>fine " XBD=800 XHG=692 YBD=1205 YHG=1171>swab " XBD=874 XHG=821 YBD=1205 YHG=1182>on " XBD=917 XHG=893 YBD=1205 YHG=1183>a " XBD=1095 XHG=936 YBD=1205 YHG=1170>flexible " XBD=1207 XHG=1115 YBD=1204 YHG=1170>wire " XBD=1372 XHG=1227 YBD=1215 YHG=1171>passed" XBD=359 XHG=184 YBD=1265 YHG=1220>through " XBD=455 XHG=385 YBD=1253 YHG=1220>the " XBD=658 XHG=481 YBD=1254 YHG=1220>anterior " XBD=799 XHG=683 YBD=1254 YHG=1231>nares " XBD=905 XHG=825 YBD=1254 YHG=1221>and " XBD=1160 XHG=930 YBD=1254 YHG=1219>inoculated " XBD=1239 XHG=1187 YBD=1254 YHG=1231>on " XBD=1375 XHG=1264 YBD=1265 YHG=1219>plain|>" XBD=520 XHG=184 YBD=1314 YHG=1269>Bordet-Gengou " XBD=728 XHG=538 YBD=1310 YHG=1269>medium, " XBD=823 XHG=749 YBD=1304 YHG=1269>but " XBD=1020 XHG=843 YBD=1304 YHG=1268>children " XBD=1106 XHG=1039 YBD=1303 YHG=1280>are " XBD=1233 XHG=1124 YBD=1303 YHG=1281>more " XBD=1375 XHG=1251 YBD=1314 YHG=1268>likely" XBD=227 XHG=183 YBD=1353 YHG=1322>to " XBD=384 XHG=250 YBD=1353 YHG=1322>resent " XBD=489 XHG=406 YBD=1352 YHG=1318>this " XBD=742 XHG=512 YBD=1364 YHG=1319>procedure. " XBD=832 XHG=796 YBD=1353 YHG=1318>A " XBD=1125 XHG=856 YBD=1364 YHG=1319>satisfactory. " XBD=1314 XHG=1138 YBD=1353 YHG=1319>medium " XBD=1372 XHG=1338 YBD=1353 YHG=1319>is" XBD=370 XHG=183 YBD=1403 YHG=1368>essential " XBD=464 XHG=402 YBD=1402 YHG=1367>for " XBD=666 XHG=498 YBD=1410 YHG=1380>success, " XBD=782 XHG=701 YBD=1402 YHG=1368>and " XBD=867 XHG=815 YBD=1403 YHG=1380>no " XBD=1028 XHG=900 YBD=1403 YHG=1369>doubt " XBD=1374 XHG=1061 YBD=1414 YHG=1368>improvements" XBD=301 XHG=182 YBD=1452 YHG=1417>could " XBD=372 XHG=322 YBD=1452 YHG=1418>be " XBD=563 XHG=393 YBD=1452 YHG=1418>effected " XBD=628 XHG=585 YBD=1452 YHG=1422>to " XBD=768 XHG=651 YBD=1452 YHG=1417>allow " XBD=841 XHG=789 YBD=1452 YHG=1430>an " XBD=1002 XHG=863 YBD=1452 YHG=1418>earlier " XBD=1157 XHG=1021 YBD=1463 YHG=1422>report " XBD=1281 XHG=1179 YBD=1452 YHG=1418>than " XBD=1372 XHG=1301 YBD=1452 YHG=1417>the" XBD=341 XHG=181 YBD=1512 YHG=1470>present " XBD=478 XHG=364 YBD=1501 YHG=1467>three " XBD=616 XHG=502 YBD=1512 YHG=1468>days. " XBD=706 XHG=669 YBD=1501 YHG=1467>A " XBD=900 XHG=731 YBD=1513 YHG=1467>striking " XBD=1078 XHG=924 YBD=1501 YHG=1468>feature " XBD=1147 XHG=1103 YBD=1501 YHG=1467>of " XBD=1237 XHG=1166 YBD=1501 YHG=1468>the " XBD=1369 XHG=1262 YBD=1501 YHG=1467>swab" XBD=336 XHG=182 YBD=1551 YHG=1516>culture " XBD=394 XHG=359 YBD=1551 YHG=1516>is " XBD=487 XHG=417 YBD=1550 YHG=1516>the " XBD=719 XHG=510 YBD=1551 YHG=1516>luxuriant " XBD=898 XHG=742 YBD=1562 YHG=1517>growth " XBD=963 XHG=921 YBD=1550 YHG=1517>in " XBD=1110 XHG=986 YBD=1562 YHG=1529>many " XBD=1255 XHG=1134 YBD=1558 YHG=1528>cases, " XBD=1368 XHG=1280 YBD=1562 YHG=1528>par-" XBD=369 XHG=180 YBD=1611 YHG=1565>ticularly " XBD=485 XHG=386 YBD=1600 YHG=1565>with " XBD=634 XHG=505 YBD=1600 YHG=1566>swabs " XBD=755 XHG=652 YBD=1600 YHG=1566>from " XBD=910 XHG=774 YBD=1611 YHG=1578>young " XBD=1116 XHG=929 YBD=1601 YHG=1565>children. " XBD=1265 XHG=1170 YBD=1601 YHG=1567>This " XBD=1371 XHG=1284 YBD=1600 YHG=1577>new" XBD=346 XHG=171 YBD=1650 YHG=1615>.method " XBD=411 XHG=367 YBD=1650 YHG=1615>of " XBD=663 XHG=427 YBD=1661 YHG=1615>diagnosing " XBD=876 XHG=683 YBD=1661 YHG=1616>pertussis " XBD=1077 XHG=895 YBD=1650 YHG=1616>deserves " XBD=1151 XHG=1098 YBD=1650 YHG=1628>an " XBD=1370 XHG=1170 YBD=1650 YHG=1615>extended" XBD=285 XHG=176 YBD=1706 YHG=1665>trial, " XBD=384 XHG=321 YBD=1699 YHG=1664>for " XBD=557 XHG=419 YBD=1699 YHG=1664>earlier " XBD=793 XHG=592 YBD=1710 YHG=1665>diagnosis " XBD=924 XHG=828 YBD=1711 YHG=1677>may " XBD=1047 XHG=957 YBD=1700 YHG=1665>lead " XBD=1126 XHG=1083 YBD=1700 YHG=1669>to " XBD=1368 XHG=1161 YBD=1710 YHG=1665>improved" XBD=366 XHG=176 YBD=1749 YHG=1714>methods " XBD=432 XHG=388 YBD=1748 YHG=1714>of " XBD=683 XHG=449 YBD=1749 YHG=1717>treatment.

ACUTE WAR NEUROSIS

" XBD=319 XHG=229 YBD=1902 YHG=1868>THE " XBD=497 XHG=333 YBD=1913 YHG=1871>pattern " XBD=556 XHG=511 YBD=1902 YHG=1867>of " XBD=684 XHG=566 YBD=1902 YHG=1871>acute " XBD=779 XHG=698 YBD=1902 YHG=1879>war " XBD=979 XHG=792 YBD=1903 YHG=1879>neuroses " XBD=1025 XHG=992 YBD=1902 YHG=1868>is " XBD=1158 XHG=1039 YBD=1902 YHG=1868>much " XBD=1242 XHG=1173 YBD=1902 YHG=1869>the " XBD=1365 XHG=1257 YBD=1902 YHG=1879>same" XBD=356 XHG=176 YBD=1952 YHG=1917>whether " XBD=471 XHG=372 YBD=1961 YHG=1917>they " XBD=589 XHG=488 YBD=1951 YHG=1917>arise " XBD=655 XHG=612 YBD=1951 YHG=1918>in " XBD=896 XHG=673 YBD=1959 YHG=1917>civilians,12 " XBD=957 XHG=915 YBD=1951 YHG=1918>in " XBD=1049 XHG=979 YBD=1952 YHG=1918>the " XBD=1235 XHG=1067 YBD=1962 YHG=1918>Army,13 " XBD=1303 XHG=1260 YBD=1952 YHG=1930>or " XBD=1368 XHG=1325 YBD=1952 YHG=1918>in" XBD=248 XHG=175 YBD=2001 YHG=1967>the |>" XBD=469 XHG=275 YBD=2000 YHG=1966>British 14 " XBD=541 XHG=496 YBD=2001 YHG=1978>or " XBD=778 XHG=565 YBD=2000 YHG=1967>American " XBD=996 XHG=805 YBD=2001 YHG=1967>Navies 15 " XBD=1074 XHG=1031 YBD=2001 YHG=1978>or " XBD=1177 XHG=1106 YBD=2000 YHG=1967>Air " XBD=1363 XHG=1208 YBD=2001 YHG=1967>Forces.

" XBD=409 XHG=176 YBD=2061 YHG=2015>Symptoms " XBD=587 XHG=428 YBD=2049 YHG=2015>include " XBD=705 XHG=608 YBD=2050 YHG=2016>such " XBD=926 XHG=727 YBD=2059 YHG=2015>objective " XBD=1134 XHG=946 YBD=2050 YHG=2016>evidence " XBD=1199 XHG=1155 YBD=2050 YHG=2015>of " XBD=1299 XHG=1215 YBD=2050 YHG=2016>fear " XBD=1363 XHG=1320 YBD=2050 YHG=2027>as" XBD=380 XHG=174 YBD=2110 YHG=2065>sweating, " XBD=582 XHG=401 YBD=2106 YHG=2068>tremors, " XBD=835 XHG=605 YBD=2100 YHG=2068>vasomotor " XBD=1093 XHG=855 YBD=2110 YHG=2065>instability, " XBD=1364 XHG=1115 YBD=2099 YHG=2065>restlessness" XBD=257 XHG=174 YBD=2148 YHG=2114>and " XBD=453 XHG=284 YBD=2149 YHG=2114>anxious " XBD=605 XHG=479 YBD=2149 YHG=2114>looks. " XBD=823 XHG=659 YBD=2148 YHG=2115>RAINES " XBD=932 XHG=851 YBD=2149 YHG=2115>and " XBD=1119 XHG=955 YBD=2148 YHG=2115>KOLB 15 " XBD=1242 XHG=1148 YBD=2149 YHG=2118>note " XBD=1364 XHG=1271 YBD=2154 YHG=2115>tbat" XBD=294 XHG=177 YBD=2198 YHG=2167>acute " XBD=406 XHG=325 YBD=2198 YHG=2175>war " XBD=629 XHG=442 YBD=2198 YHG=2175>neuroses " XBD=758 XHG=661 YBD=2208 YHG=2175>may " XBD=956 XHG=789 YBD=2209 YHG=2163>develop " XBD=1032 XHG=989 YBD=2197 YHG=2164>in " XBD=1240 XHG=1064 YBD=2208 YHG=2164>subjects " XBD=1362 XHG=1271 YBD=2198 YHG=2164>who" XBD=324 XHG=173 YBD=2259 YHG=2224>appear " XBD=479 XHG=351 YBD=2247 YHG=2212>stable " XBD=588 XHG=506 YBD=2247 YHG=2213>and " XBD=906 XHG=611 YBD=2257 YHG=2212>well-adjusted " XBD=1064 XHG=931 YBD=2247 YHG=2213>before " XBD=1287 XHG=1094 YBD=2258 YHG=2223>exposure " XBD=1362 XHG=1317 YBD=2247 YHG=2216>to" XBD=244 XHG=172 YBD=2297 YHG=2262>the " XBD=542 XHG=258 YBD=2308 YHG=2262>precipitating " XBD=773 XHG=555 YBD=2297 YHG=2262>emotional " XBD=1055 XHG=787 YBD=2296 YHG=2262>disturbance. " XBD=1306 XHG=1095 YBD=2297 YHG=2262>Incidence " XBD=1366 XHG=1321 YBD=2296 YHG=2261>of" XBD=360 XHG=174 YBD=2347 YHG=2323>neuroses " XBD=468 XHG=387 YBD=2346 YHG=2312>and " XBD=564 XHG=494 YBD=2347 YHG=2311>the " XBD=759 XHG=590 YBD=2346 YHG=2314>amount " XBD=831 XHG=786 YBD=2345 YHG=2310>of " XBD=975 XHG=854 YBD=2346 YHG=2315>stress " XBD=1222 XHG=1000 YBD=2357 YHG=2304>provoking " XBD=1361 XHG=1249 YBD=2345 YHG=2311>them" XBD=269 XHG=172 YBD=2395 YHG=2365>turn " XBD=336 XHG=292 YBD=2396 YHG=2365>to " XBD=468 XHG=360 YBD=2396 YHG=2373>some " XBD=633 XHG=492 YBD=2396 YHG=2364>extent " XBD=710 XHG=657 YBD=2395 YHG=2373>on " XBD=802 XHG=732 YBD=2395 YHG=2361>the " XBD=984 XHG=827 YBD=2405 YHG=2360>quality " XBD=1051 XHG=1007 YBD=2395 YHG=2360>of " XBD=1140 XHG=1070 YBD=2395 YHG=2360>the " XBD=1359 XHG=1163 YBD=2395 YHG=2360>material." XBD=419 XHG=173 YBD=2445 YHG=2410>SYMONDS 16 " XBD=529 XHG=455 YBD=2445 YHG=2411>has " XBD=687 XHG=567 YBD=2455 YHG=2411>given " XBD=784 XHG=731 YBD=2444 YHG=2421>an " XBD=994 XHG=822 YBD=2444 YHG=2413>account " XBD=1077 XHG=1032 YBD=2445 YHG=2408>of " XBD=1177 XHG=1107 YBD=2444 YHG=2410>the " XBD=1363 XHG=1211 YBD=2444 YHG=2409>human" XBD=359 XHG=172 YBD=2504 YHG=2470>response " XBD=428 XHG=384 YBD=2494 YHG=2463>to " XBD=577 XHG=453 YBD=2504 YHG=2459>flying " XBD=725 XHG=604 YBD=2493 YHG=2463>stress " XBD=794 XHG=751 YBD=2493 YHG=2470>as " XBD=913 XHG=820 YBD=2493 YHG=2470>seen " XBD=979 XHG=936 YBD=2492 YHG=2459>in " XBD=1112 XHG=1003 YBD=2493 YHG=2458>RAF " XBD=1359 XHG=1136 YBD=2503 YHG=2457>personnel." XBD=248 XHG=171 YBD=2542 YHG=2508>His " XBD=370 XHG=262 YBD=2543 YHG=2520>cases " XBD=484 XHG=384 YBD=2543 YHG=2520>were " XBD=632 XHG=497 YBD=2553 YHG=2520>young " XBD=751 XHG=646 YBD=2549 YHG=2520>men, " XBD=890 XHG=766 YBD=2553 YHG=2519>many " XBD=944 XHG=902 YBD=2542 YHG=2508>in " XBD=1027 XHG=957 YBD=2542 YHG=2508>the " XBD=1151 XHG=1041 YBD=2552 YHG=2507>early " XBD=1360 XHG=1164 YBD=2549 YHG=2508>twenties," XBD=254 XHG=171 YBD=2592 YHG=2557>and " XBD=400 XHG=276 YBD=2602 YHG=2557>likely " XBD=466 XHG=421 YBD=2592 YHG=2561>to " XBD=540 XHG=490 YBD=2592 YHG=2558>be " XBD=665 XHG=564 YBD=2592 YHG=2558>both " XBD=812 XHG=690 YBD=2592 YHG=2558>brave " XBD=917 XHG=836 YBD=2592 YHG=2557>and " XBD=1093 XHG=941 YBD=2591 YHG=2557>skilled. " XBD=1210 XHG=1146 YBD=2591 YHG=2556>He " XBD=1361 XHG=1234 YBD=2591 YHG=2560>states" XBD=242 XHG=170 YBD=2640 YHG=2606>the " XBD=366 XHG=261 YBD=2641 YHG=2607>issue " XBD=428 XHG=385 YBD=2641 YHG=2607>in " XBD=735 XHG=447 YBD=2652 YHG=2606>physiological " XBD=890 XHG=754 YBD=2642 YHG=2610>terms. " XBD=1178 XHG=944 YBD=2647 YHG=2606>Inhibition, " XBD=1250 XHG=1199 YBD=2640 YHG=2606>he " XBD=1359 XHG=1271 YBD=2650 YHG=2617>sug-" XBD=290 XHG=169 YBD=2699 YHG=2658>gests, " XBD=353 XHG=320 YBD=2689 YHG=2656>is " XBD=453 XHG=383 YBD=2689 YHG=2655>the " XBD=589 XHG=482 YBD=2690 YHG=2656>basis " XBD=664 XHG=619 YBD=2690 YHG=2655>of " XBD=877 XHG=688 YBD=2700 YHG=2656>acquired " XBD=1169 XHG=905 YBD=2696 YHG=2655>fearlessness, " XBD=1281 XHG=1200 YBD=2689 YHG=2655>and " XBD=1360 XHG=1308 YBD=2689 YHG=2655>he" XBD=389 XHG=169 YBD=2738 YHG=2703>illustrates " XBD=477 XHG=406 YBD=2739 YHG=2704>the " XBD=666 XHG=497 YBD=2749 YHG=2708>concept " XBD=788 XHG=685 YBD=2739 YHG=2704>from " XBD=1028 XHG=807 YBD=2739 YHG=2704>excitation " XBD=1126 XHG=1045 YBD=2738 YHG=2704>and " XBD=1360 XHG=1144 YBD=2738 YHG=2704>inhibition" XBD=213 XHG=170 YBD=2786 YHG=2753>in " XBD=307 XHG=237 YBD=2787 YHG=2753>the " XBD=451 XHG=329 YBD=2787 YHG=2752>reflex " XBD=543 XHG=476 YBD=2788 YHG=2764>arc " XBD=614 XHG=568 YBD=2787 YHG=2753>of " XBD=657 XHG=633 YBD=2787 YHG=2765>a " XBD=812 XHG=683 YBD=2798 YHG=2753>spinal " XBD=880 XHG=836 YBD=2787 YHG=2765>or " XBD=1157 XHG=904 YBD=2788 YHG=2753>decerebrate " XBD=1356 XHG=1181 YBD=2788 YHG=2752>animal :" XBD=196 XHG=172 YBD=2814 YHG=2800>&dquo; " XBD=249 XHG=212 YBD=2835 YHG=2801>A " XBD=406 XHG=269 YBD=2846 YHG=2805>strong " XBD=648 XHG=425 YBD=2846 YHG=2801>inhibitory " XBD=854 XHG=668 YBD=2836 YHG=2802>stimulus " XBD=951 XHG=873 YBD=2836 YHG=2802>will " XBD=1138 XHG=971 YBD=2843 YHG=2802>abolish, " XBD=1184 XHG=1160 YBD=2836 YHG=2814>a " XBD=1359 XHG=1204 YBD=2836 YHG=2802>weaker" XBD=390 XHG=168 YBD=2895 YHG=2850>inhibitory " XBD=601 XHG=415 YBD=2885 YHG=2850>stimulus " XBD=705 XHG=626 YBD=2885 YHG=2850>will " XBD=826 XHG=731 YBD=2896 YHG=2851>only " XBD=1050 XHG=850 YBD=2892 YHG=2851>diminish, " XBD=1148 XHG=1077 YBD=2885 YHG=2852>the " XBD=1290 XHG=1173 YBD=2885 YHG=2851>effect " XBD=1362 XHG=1316 YBD=2885 YHG=2849>of" XBD=239 XHG=168 YBD=2933 YHG=2899>the " XBD=370 XHG=262 YBD=2933 YHG=2910>same " XBD=619 XHG=392 YBD=2943 YHG=2899>excitatory " XBD=868 XHG=642 YBD=2934 YHG=2899>stimulus.&dquo; " XBD=986 XHG=924 YBD=2934 YHG=2899>On " XBD=1089 XHG=1007 YBD=2934 YHG=2899>this " XBD=1284 XHG=1112 YBD=2944 YHG=2899>analogy " XBD=1356 XHG=1304 YBD=2933 YHG=2900>he" XBD=298 XHG=168 YBD=2981 YHG=2951>traces " XBD=800 XHG=309 YBD=2993 YHG=2947>the fluctuationsduring " XBD=1036 XHG=812 YBD=2992 YHG=2949>training in " XBD=1116 XHG=1046 YBD=2982 YHG=2948>the " XBD=1357 XHG=1130 YBD=2982 YHG=2948>confidence" XBD=213 XHG=167 YBD=3030 YHG=2995>of " XBD=294 XHG=224 YBD=3030 YHG=2996>the " XBD=479 XHG=310 YBD=3040 YHG=3007>average " XBD=608 XHG=494 YBD=3040 YHG=2996>pilot, " XBD=682 XHG=626 YBD=3040 YHG=2996>by " XBD=964 XHG=698 YBD=3031 YHG=2997>constitution " XBD=1133 XHG=979 YBD=3031 YHG=2996>neither " XBD=1267 XHG=1149 YBD=3030 YHG=2997>timid " XBD=1357 XHG=1282 YBD=3031 YHG=3007>nor" XBD=339 XHG=167 YBD=3078 YHG=3044>fearless. " XBD=479 XHG=394 YBD=3078 YHG=3044>The " XBD=583 XHG=496 YBD=3078 YHG=3044>first " XBD=703 XHG=604 YBD=3078 YHG=3044>time " XBD=756 XHG=732 YBD=3079 YHG=3057>a " XBD=882 XHG=780 YBD=3088 YHG=3044>pilot " XBD=992 XHG=899 YBD=3089 YHG=3056>goes " XBD=1065 XHG=1010 YBD=3089 YHG=3056>up " XBD=1140 XHG=1089 YBD=3078 YHG=3045>he " XBD=1356 XHG=1157 YBD=3089 YHG=3045>probably" XBD=262 XHG=166 YBD=3127 YHG=3092>feels " XBD=405 XHG=285 YBD=3138 YHG=3093>slight " XBD=524 XHG=426 YBD=3134 YHG=3092>fear, " XBD=648 XHG=549 YBD=3126 YHG=3104>soon " XBD=867 XHG=669 YBD=3127 YHG=3093>inhibited " XBD=944 XHG=889 YBD=3137 YHG=3093>by " XBD=1081 XHG=967 YBD=3128 YHG=3093>other " XBD=1243 XHG=1103 YBD=3127 YHG=3093>affects " XBD=1354 XHG=1265 YBD=3138 YHG=3104>pro-

11. Gorfinkel, M. Sth Afr. med. J. 1941, 15, 451. See Lancet,1942, i, 176.

12. Sargant, W. Brit. med. J. 1942, ii, 574.13. Sargant, W. and Slater, E. Lancet, 1940, ii, 1. Love, H. R.

Med. J. Austr. 1942, ii, 137 ; Craigie, H. B. Brit. med. J. 1942,ii, 675.

14. Stephenson, G. V. and Cameron, K. Brit. med. J. 1943, ii, 603.15. Raines, G. N. and Kolb, L. C. U.S. Naval med. Bull. 1943, 41,

603.16. Symonds, C. P. Brit. med. J. 1943, ii, 703 and 740.

" XBD=1580 XHG=1448 YBD=225 YHG=192>voked " XBD=1663 XHG=1608 YBD=236 YHG=192>by " XBD=1758 XHG=1689 YBD=225 YHG=192>the " XBD=1917 XHG=1786 YBD=232 YHG=194>event, " XBD=2113 XHG=1946 YBD=235 YHG=190>notably " XBD=2400 XHG=2140 YBD=236 YHG=191>professional " XBD=2617 XHG=2426 YBD=227 YHG=191>keenness." XBD=1731 XHG=1448 YBD=285 YHG=240>Conditioning " XBD=1811 XHG=1756 YBD=284 YHG=241>by " XBD=2066 XHG=1837 YBD=285 YHG=240>experience " XBD=2177 XHG=2094 YBD=273 YHG=240>also " XBD=2373 XHG=2207 YBD=274 YHG=240>inhibits " XBD=2495 XHG=2400 YBD=273 YHG=240>fear. " XBD=2617 XHG=2543 YBD=274 YHG=240>The" XBD=1532 XHG=1446 YBD=323 YHG=288>first " XBD=1645 XHG=1562 YBD=323 YHG=289>solo " XBD=1786 XHG=1671 YBD=333 YHG=289>flight " XBD=1895 XHG=1815 YBD=323 YHG=290>and " XBD=1991 XHG=1922 YBD=323 YHG=289>the " XBD=2103 XHG=2017 YBD=323 YHG=288>first " XBD=2308 XHG=2131 YBD=334 YHG=292>attempt " XBD=2379 XHG=2336 YBD=323 YHG=292>at " XBD=2618 XHG=2408 YBD=323 YHG=288>aerobatics" XBD=1579 XHG=1445 YBD=373 YHG=338>follow " XBD=1674 XHG=1604 YBD=372 YHG=338>the " XBD=1808 XHG=1701 YBD=373 YHG=349>same course " XBD=2123 XHG=1990 YBD=372 YHG=337>fear " XBD=2180 XHG=2148 YBD=371 YHG=338>is " XBD=2365 XHG=2207 YBD=372 YHG=338>excited " XBD=2471 XHG=2391 YBD=372 YHG=338>and " XBD=2618 XHG=2498 YBD=371 YHG=337>subse-" XBD=1616 XHG=1446 YBD=432 YHG=387>quently " XBD=1842 XHG=1634 YBD=421 YHG=387>inhibited. " XBD=2073 XHG=1897 YBD=428 YHG=387>Crashes, " XBD=2216 XHG=2094 YBD=421 YHG=387>death " XBD=2281 XHG=2236 YBD=421 YHG=386>of " XBD=2457 XHG=2296 YBD=427 YHG=387>friends, " XBD=2619 XHG=2478 YBD=421 YHG=398>narrow" XBD=1607 XHG=1445 YBD=481 YHG=447>escapes " XBD=1765 XHG=1623 YBD=481 YHG=436>during " XBD=1955 XHG=1781 YBD=480 YHG=436>training " XBD=2024 XHG=1973 YBD=470 YHG=436>all " XBD=2169 XHG=2041 YBD=470 YHG=436>excite " XBD=2281 XHG=2185 YBD=476 YHG=436>fear, " XBD=2382 XHG=2301 YBD=470 YHG=436>and " XBD=2517 XHG=2399 YBD=479 YHG=446>every " XBD=2619 XHG=2532 YBD=469 YHG=436>time" XBD=1526 XHG=1444 YBD=518 YHG=485>this " XBD=1733 XHG=1551 YBD=529 YHG=485>happens " XBD=1826 XHG=1756 YBD=519 YHG=485>the " XBD=2077 XHG=1851 YBD=528 YHG=485>inhibitory- " XBD=2201 XHG=2096 YBD=518 YHG=488>state " XBD=2288 XHG=2227 YBD=519 YHG=485>for " XBD=2422 XHG=2315 YBD=519 YHG=495>some " XBD=2560 XHG=2447 YBD=517 YHG=484>kinds " XBD=2622 XHG=2583 YBD=518 YHG=484>of" XBD=1696 XHG=1443 YBD=567 YHG=532>fearlessness " XBD=1766 XHG=1733 YBD=567 YHG=533>is " XBD=2040 XHG=1803 YBD=574 YHG=533>weakened ; " XBD=2326 XHG=2096 YBD=578 YHG=533>experience " XBD=2618 XHG=2364 YBD=567 YHG=532>reconditions" XBD=1671 XHG=1442 YBD=623 YHG=582>inhibition, " XBD=1775 XHG=1700 YBD=617 YHG=582>but " XBD=1844 XHG=1800 YBD=617 YHG=586>at " XBD=1939 XHG=1869 YBD=617 YHG=582>the " XBD=2071 XHG=1966 YBD=617 YHG=594>same " XBD=2195 XHG=2097 YBD=617 YHG=582>time " XBD=2370 XHG=2222 YBD=616 YHG=583>widens " XBD=2465 XHG=2396 YBD=616 YHG=582>the " XBD=2615 XHG=2490 YBD=626 YHG=581>pilot’s" XBD=1673 XHG=1441 YBD=676 YHG=631>knowledge " XBD=1736 XHG=1691 YBD=665 YHG=631>of " XBD=1818 XHG=1748 YBD=666 YHG=632>the " XBD=1969 XHG=1835 YBD=676 YHG=632>things " XBD=2113 XHG=1986 YBD=666 YHG=632>which " XBD=2226 XHG=2131 YBD=676 YHG=644>may " XBD=2292 XHG=2242 YBD=677 YHG=644>go " XBD=2456 XHG=2310 YBD=676 YHG=642>wrong, " XBD=2518 XHG=2476 YBD=664 YHG=642>so " XBD=2617 XHG=2534 YBD=665 YHG=631>that" XBD=1511 XHG=1441 YBD=715 YHG=681>the " XBD=1703 XHG=1537 YBD=715 YHG=680>balance " XBD=1822 XHG=1728 YBD=714 YHG=692>over " XBD=1871 XHG=1848 YBD=714 YHG=692>a " XBD=1988 XHG=1896 YBD=725 YHG=680>long " XBD=2150 XHG=2012 YBD=725 YHG=681>period " XBD=2307 XHG=2175 YBD=714 YHG=681>would " XBD=2540 XHG=2332 YBD=725 YHG=679>gradually " XBD=2615 XHG=2562 YBD=725 YHG=680>tip" XBD=1617 XHG=1441 YBD=764 YHG=730>towards " XBD=1734 XHG=1639 YBD=763 YHG=729>fear. |>" XBD=1931 XHG=1788 YBD=763 YHG=729>Before " XBD=2043 XHG=1952 YBD=764 YHG=730>that " XBD=2140 XHG=2067 YBD=763 YHG=741>can " XBD=2334 XHG=2161 YBD=774 YHG=730>happen, " XBD=2550 XHG=2358 YBD=770 YHG=729>however, " XBD=2615 XHG=2572 YBD=763 YHG=729>he" XBD=1603 XHG=1440 YBD=818 YHG=779>reaches " XBD=1695 XHG=1625 YBD=812 YHG=778>the " XBD=1964 XHG=1717 YBD=823 YHG=779>operational " XBD=2087 XHG=1986 YBD=819 YHG=779>unit, " XBD=2239 XHG=2110 YBD=812 YHG=778>where " XBD=2310 XHG=2259 YBD=812 YHG=779>he " XBD=2365 XHG=2331 YBD=812 YHG=779>is " XBD=2558 XHG=2387 YBD=823 YHG=778>exposed " XBD=2615 XHG=2577 YBD=812 YHG=780>to" XBD=1528 XHG=1440 YBD=862 YHG=840>new " XBD=1694 XHG=1544 YBD=873 YHG=828>danger " XBD=1812 XHG=1710 YBD=862 YHG=827>from " XBD=1922 XHG=1830 YBD=872 YHG=827>long " XBD=2052 XHG=1940 YBD=872 YHG=828>trips, " XBD=2151 XHG=2072 YBD=861 YHG=828>bad " XBD=2344 XHG=2168 YBD=861 YHG=827>weather " XBD=2442 XHG=2361 YBD=861 YHG=828>and " XBD=2614 XHG=2460 YBD=871 YHG=823>fatigde:" XBD=1570 XHG=1439 YBD=912 YHG=877>When |>" XBD=1799 XHG=1591 YBD=922 YHG=874>he begins " XBD=2048 XHG=1823 YBD=922 YHG=877>operations " XBD=2182 XHG=2071 YBD=910 YHG=876>there " XBD=2267 XHG=2202 YBD=911 YHG=888>are " XBD=2335 XHG=2291 YBD=910 YHG=876>of " XBD=2496 XHG=2356 YBD=920 YHG=887>course " XBD=2614 XHG=2514 YBD=910 YHG=876>addi-" XBD=1567 XHG=1439 YBD=960 YHG=924>tional " XBD=1686 XHG=1584 YBD=960 YHG=926>risks " XBD=1894 XHG=1704 YBD=961 YHG=926>from the " XBD=2066 XHG=1904 YBD=970 YHG=937>enemy. " XBD=2175 XHG=2119 YBD=960 YHG=925>At " XBD=2279 XHG=2192 YBD=960 YHG=925>first " XBD=2347 XHG=2297 YBD=960 YHG=926>he " XBD=2398 XHG=2365 YBD=959 YHG=925>is " XBD=2614 XHG=2416 YBD=971 YHG=926>protected" XBD=1496 XHG=1440 YBD=1020 YHG=976>by " XBD=1587 XHG=1516 YBD=1009 YHG=976>the " XBD=1858 XHG=1608 YBD=1010 YHG=966>fearlessness " XBD=1924 XHG=1879 YBD=1010 YHG=975>of " XBD=2213 XHG=1940 YBD=1020 YHG=975>inexperience " XBD=2315 XHG=2234 YBD=1009 YHG=976>and " XBD=2392 XHG=2337 YBD=1020 YHG=975>by " XBD=2614 XHG=2411 YBD=1011 YHG=975>inhibition" XBD=1517 XHG=1439 YBD=1059 YHG=1025>due " XBD=1581 XHG=1537 YBD=1059 YHG=1028>to " XBD=1805 XHG=1604 YBD=1069 YHG=1025>curiosity. " XBD=1993 XHG=1847 YBD=1059 YHG=1023>This is " XBD=2110 XHG=2014 YBD=1058 YHG=1036>soon " XBD=2220 XHG=2129 YBD=1066 YHG=1024>lost, " XBD=2317 XHG=2242 YBD=1058 YHG=1024>but " XBD=2381 XHG=2337 YBD=1058 YHG=1036>as " XBD=2469 XHG=2400 YBD=1058 YHG=1024>the " XBD=2614 XHG=2490 YBD=1069 YHG=1035>opera-" XBD=1567 XHG=1439 YBD=1108 YHG=1073>tional " XBD=1684 XHG=1592 YBD=1108 YHG=1077>tour " XBD=1800 XHG=1708 YBD=1119 YHG=1085>goes " XBD=1878 XHG=1825 YBD=1108 YHG=1086>on " XBD=2131 XHG=1902 YBD=1119 YHG=1074>experience " XBD=2274 XHG=2156 YBD=1118 YHG=1073>again " XBD=2509 XHG=2298 YBD=1108 YHG=1073>reinforces " XBD=2613 XHG=2533 YBD=1108 YHG=1085>con-" XBD=1614 XHG=1438 YBD=1164 YHG=1122>fidence ; " XBD=1697 XHG=1646 YBD=1157 YHG=1135>on " XBD=1781 XHG=1711 YBD=1158 YHG=1123>the " XBD=1910 XHG=1795 YBD=1158 YHG=1123>other " XBD=2029 XHG=1920 YBD=1157 YHG=1123>hand " XBD=2076 XHG=2042 YBD=1157 YHG=1124>it " XBD=2205 XHG=2088 YBD=1168 YHG=1124>again " XBD=2320 XHG=2219 YBD=1157 YHG=1123>adds " XBD=2378 XHG=2334 YBD=1157 YHG=1126>to " XBD=2611 XHG=2392 YBD=1168 YHG=1122>knowledge" XBD=1484 XHG=1439 YBD=1206 YHG=1172>of " XBD=1680 XHG=1498 YBD=1217 YHG=1173>dangers, " XBD=1745 XHG=1702 YBD=1206 YHG=1184>so " XBD=2029 XHG=1764 YBD=1217 YHG=1172>anticipation " XBD=2092 XHG=2047 YBD=1207 YHG=1172>of " XBD=2176 XHG=2106 YBD=1207 YHG=1172>the " XBD=2291 XHG=2193 YBD=1206 YHG=1176>next " XBD=2424 XHG=2308 YBD=1217 YHG=1172>flight " XBD=2612 XHG=2443 YBD=1208 YHG=1172>becomes" XBD=1462 XHG=1438 YBD=1255 YHG=1233>a " XBD=1651 XHG=1494 YBD=1266 YHG=1225>greater " XBD=1821 XHG=1683 YBD=1256 YHG=1222>strain. " XBD=2042 XHG=1875 YBD=1267 YHG=1221>Fatigue " XBD=2256 XHG=2075 YBD=1256 YHG=1222>weakens " XBD=2516 XHG=2288 YBD=1262 YHG=1221>inhibition, " XBD=2614 XHG=2548 YBD=1257 YHG=1222>but" XBD=1642 XHG=1439 YBD=1316 YHG=1271>squadron " XBD=1729 XHG=1649 YBD=1305 YHG=1271>and " XBD=1837 XHG=1737 YBD=1305 YHG=1282>crew " XBD=1996 XHG=1847 YBD=1306 YHG=1271>morale " XBD=2095 XHG=2003 YBD=1316 YHG=1270>help " XBD=2149 XHG=2106 YBD=1305 YHG=1274>to " XBD=2354 XHG=2156 YBD=1305 YHG=1271>maintain " XBD=2411 XHG=2365 YBD=1305 YHG=1271>it. " XBD=2612 XHG=2435 YBD=1308 YHG=1271>Towards" XBD=1508 XHG=1437 YBD=1355 YHG=1320>the " XBD=1599 XHG=1521 YBD=1355 YHG=1321>end " XBD=1657 XHG=1613 YBD=1354 YHG=1320>of " XBD=1735 XHG=1665 YBD=1354 YHG=1320>the " XBD=1841 XHG=1748 YBD=1355 YHG=1324>tour " XBD=1977 XHG=1853 YBD=1365 YHG=1332>many " XBD=2137 XHG=1988 YBD=1354 YHG=1319>factors " XBD=2383 XHG=2150 YBD=1355 YHG=1320>undermine " XBD=2613 XHG=2398 YBD=1356 YHG=1320>confidence" XBD=1755 XHG=1435 YBD=1415 YHG=1370>-anticipation " XBD=1843 XHG=1798 YBD=1404 YHG=1369>of " XBD=1995 XHG=1880 YBD=1404 YHG=1368>relief " XBD=2112 XHG=2032 YBD=1404 YHG=1370>and " XBD=2337 XHG=2153 YBD=1414 YHG=1369>holidays " XBD=2515 XHG=2379 YBD=1404 YHG=1370>makes " XBD=2613 XHG=2554 YBD=1405 YHG=1370>life" XBD=1630 XHG=1436 YBD=1465 YHG=1419>precious, " XBD=1736 XHG=1655 YBD=1454 YHG=1420>and " XBD=1911 XHG=1758 YBD=1465 YHG=1419>fatigue " XBD=1966 XHG=1933 YBD=1453 YHG=1420>is " XBD=2285 XHG=1992 YBD=1454 YHG=1418>cumulative. " XBD=2384 XHG=2301 YBD=1453 YHG=1419>The " XBD=2613 XHG=2408 YBD=1454 YHG=1420>emotional" XBD=1595 XHG=1436 YBD=1503 YHG=1469>tension " XBD=1646 XHG=1613 YBD=1502 YHG=1469>is " XBD=1760 XHG=1664 YBD=1502 YHG=1469>thus " XBD=1847 XHG=1778 YBD=1503 YHG=1469>the " XBD=1974 XHG=1868 YBD=1502 YHG=1468>chief " XBD=2163 XHG=1994 YBD=1503 YHG=1468>element " XBD=2224 XHG=2181 YBD=1502 YHG=1469>in " XBD=2370 XHG=2245 YBD=1513 YHG=1468>flying " XBD=2520 XHG=2390 YBD=1510 YHG=1472>stress, " XBD=2612 XHG=2540 YBD=1504 YHG=1470>and" XBD=1505 XHG=1435 YBD=1553 YHG=1519>the " XBD=1633 XHG=1526 YBD=1552 YHG=1521>most " XBD=1864 XHG=1653 YBD=1563 YHG=1517>fatiguing." XBD=1737 XHG=1486 YBD=1609 YHG=1575>Breakdown " XBD=1844 XHG=1748 YBD=1620 YHG=1586>may " XBD=1950 XHG=1854 YBD=1609 YHG=1578>turn " XBD=2014 XHG=1962 YBD=1608 YHG=1586>on " XBD=2210 XHG=2025 YBD=1609 YHG=1574>different " XBD=2372 XHG=2222 YBD=1609 YHG=1575>factors " XBD=2425 XHG=2382 YBD=1609 YHG=1575>in " XBD=2609 XHG=2435 YBD=1610 YHG=1574>different" XBD=1526 XHG=1433 YBD=1660 YHG=1636>men " XBD=1595 XHG=1551 YBD=1659 YHG=1636>as " XBD=1861 XHG=1621 YBD=1659 YHG=1624>SYMONDS&dquo; " XBD=1956 XHG=1884 YBD=1658 YHG=1624>has " XBD=2146 XHG=1980 YBD=1669 YHG=1624>pointed " XBD=2237 XHG=2165 YBD=1659 YHG=1625>out " XBD=2303 XHG=2261 YBD=1659 YHG=1624>in " XBD=2401 XHG=2329 YBD=1659 YHG=1636>our " XBD=2607 XHG=2427 YBD=1659 YHG=1624>columns." XBD=1484 XHG=1434 YBD=1709 YHG=1675>In " XBD=1579 XHG=1508 YBD=1708 YHG=1674>the " XBD=1711 XHG=1603 YBD=1708 YHG=1674>RAF " XBD=1971 XHG=1735 YBD=1719 YHG=1673>particulars " XBD=2063 XHG=1997 YBD=1708 YHG=1686>are " XBD=2281 XHG=2089 YBD=1708 YHG=1673>collected " XBD=2361 XHG=2305 YBD=1719 YHG=1674>by " XBD=2454 XHG=2384 YBD=1708 YHG=1674>the " XBD=2607 XHG=2479 YBD=1709 YHG=1685>neuro-" XBD=1676 XHG=1433 YBD=1770 YHG=1724>psychiatric " XBD=1920 XHG=1700 YBD=1768 YHG=1723>specialists " XBD=2014 XHG=1941 YBD=1758 YHG=1727>not " XBD=2131 XHG=2036 YBD=1768 YHG=1723>only " XBD=2197 XHG=2153 YBD=1758 YHG=1723>of " XBD=2286 XHG=2216 YBD=1758 YHG=1724>the " XBD=2437 XHG=2307 YBD=1758 YHG=1724>man’s " XBD=2610 XHG=2460 YBD=1765 YHG=1724>service," XBD=1558 XHG=1433 YBD=1819 YHG=1773>flying " XBD=1699 XHG=1577 YBD=1807 YHG=1774>hours " XBD=1799 XHG=1719 YBD=1808 YHG=1774>and " XBD=1950 XHG=1819 YBD=1807 YHG=1773>duties " XBD=2045 XHG=1969 YBD=1807 YHG=1773>but " XBD=2110 XHG=2066 YBD=1807 YHG=1772>of " XBD=2323 XHG=2125 YBD=1807 YHG=1773>incidents " XBD=2471 XHG=2343 YBD=1808 YHG=1773>which " XBD=2610 XHG=2491 YBD=1818 YHG=1773>might" XBD=1482 XHG=1432 YBD=1857 YHG=1823>be " XBD=1948 XHG=1505 YBD=1868 YHG=1822>responsible-weight " XBD=2018 XHG=1973 YBD=1857 YHG=1821>of " XBD=2161 XHG=2037 YBD=1868 YHG=1821>flying " XBD=2305 XHG=2185 YBD=1857 YHG=1826>stress " XBD=2546 XHG=2327 YBD=1867 YHG=1822>(measured " XBD=2610 XHG=2556 YBD=1869 YHG=1822>by" XBD=1501 XHG=1431 YBD=1906 YHG=1873>the " XBD=1687 XHG=1517 YBD=1907 YHG=1875>amount " XBD=1772 XHG=1702 YBD=1906 YHG=1872>the " XBD=1977 XHG=1788 YBD=1916 YHG=1872>ordinary " XBD=2085 XHG=1990 YBD=1907 YHG=1883>man " XBD=2177 XHG=2102 YBD=1906 YHG=1884>can " XBD=2317 XHG=2191 YBD=1915 YHG=1872>take), " XBD=2405 XHG=2335 YBD=1906 YHG=1872>the " XBD=2558 XHG=2421 YBD=1917 YHG=1872>degree " XBD=2612 XHG=2574 YBD=1906 YHG=1870>of" XBD=1626 XHG=1431 YBD=1956 YHG=1922>domestic " XBD=1731 XHG=1650 YBD=1956 YHG=1921>and " XBD=1936 XHG=1752 YBD=1967 YHG=1920>personal " XBD=2091 XHG=1959 YBD=1962 YHG=1924>stress, " XBD=2196 XHG=2116 YBD=1956 YHG=1921>and " XBD=2289 XHG=2220 YBD=1955 YHG=1922>the " XBD=2610 XHG=2312 YBD=1967 YHG=1921>predisposition" XBD=1475 XHG=1431 YBD=2005 YHG=1974>to " XBD=1733 XHG=1507 YBD=2005 YHG=1970>functional " XBD=1931 XHG=1760 YBD=2005 YHG=1982>nervous " XBD=2147 XHG=1959 YBD=2006 YHG=1970>disorder. " XBD=2449 XHG=2203 YBD=2005 YHG=1970>SYMONDS 16 " XBD=2608 XHG=2478 YBD=2015 YHG=1968>quotes" XBD=1543 XHG=1429 YBD=2054 YHG=2020>three " XBD=1686 XHG=1567 YBD=2067 YHG=2031>cases " XBD=1761 XHG=1718 YBD=2053 YHG=2020>in " XBD=1921 XHG=1792 YBD=2054 YHG=2019>which " XBD=2140 XHG=1953 YBD=2054 YHG=2031>neuroses " XBD=2420 XHG=2173 YBD=2064 YHG=2019>developed : " XBD=2543 XHG=2471 YBD=2054 YHG=2030>one " XBD=2609 XHG=2572 YBD=2052 YHG=2019>in" XBD=1559 XHG=1428 YBD=2103 YHG=2069>which " XBD=1780 XHG=1572 YBD=2104 YHG=2068>abnormal " XBD=1916 XHG=1791 YBD=2118 YHG=2068>flying " XBD=2009 XHG=1929 YBD=2103 YHG=2069>and " XBD=2214 XHG=2021 YBD=2104 YHG=2069>domestic " XBD=2349 XHG=2228 YBD=2103 YHG=2072>stress " XBD=2462 XHG=2361 YBD=2103 YHG=2080>were " XBD=2608 XHG=2474 YBD=2103 YHG=2068>absent" XBD=1509 XHG=1428 YBD=2153 YHG=2119>and " XBD=1839 XHG=1528 YBD=2164 YHG=2118>predisposition " XBD=2019 XHG=1859 YBD=2159 YHG=2129>severe ; " XBD=2129 XHG=2055 YBD=2153 YHG=2130>one " XBD=2189 XHG=2147 YBD=2152 YHG=2118>in " XBD=2337 XHG=2208 YBD=2152 YHG=2118>which " XBD=2480 XHG=2355 YBD=2163 YHG=2117>flying " XBD=2609 XHG=2499 YBD=2167 YHG=2121>stress" XBD=1509 XHG=1427 YBD=2202 YHG=2179>was " XBD=1658 XHG=1524 YBD=2213 YHG=2167>slight, " XBD=1984 XHG=1675 YBD=2213 YHG=2168>predisposition " XBD=2141 XHG=1999 YBD=2202 YHG=2168>absent " XBD=2238 XHG=2157 YBD=2202 YHG=2168>and " XBD=2447 XHG=2253 YBD=2202 YHG=2167>domestic " XBD=2648 XHG=2461 YBD=2216 YHG=2162>worries" XBD=1605 XHG=1428 YBD=2259 YHG=2217>serious ; " XBD=1726 XHG=1645 YBD=2251 YHG=2217>and " XBD=1826 XHG=1752 YBD=2251 YHG=2229>one " XBD=1892 XHG=1850 YBD=2251 YHG=2217>in " XBD=2043 XHG=1916 YBD=2251 YHG=2217>which " XBD=2191 XHG=2067 YBD=2262 YHG=2217>flying " XBD=2336 XHG=2216 YBD=2251 YHG=2218>stress " XBD=2441 XHG=2360 YBD=2251 YHG=2228>was " XBD=2604 XHG=2466 YBD=2256 YHG=2227>severe," XBD=1737 XHG=1426 YBD=2312 YHG=2266>predisposition " XBD=1966 XHG=1760 YBD=2301 YHG=2262>moderate " XBD=2071 XHG=1991 YBD=2301 YHG=2267>and " XBD=2288 XHG=2095 YBD=2301 YHG=2267>domestic " XBD=2434 XHG=2314 YBD=2300 YHG=2269>stress " XBD=2605 XHG=2460 YBD=2300 YHG=2265>absent." XBD=1643 XHG=1425 YBD=2360 YHG=2315>Naturally " XBD=1722 XHG=1668 YBD=2349 YHG=2315>all " XBD=1907 XHG=1747 YBD=2360 YHG=2315>degrees " XBD=1978 XHG=1934 YBD=2350 YHG=2315>of " XBD=2167 XHG=2001 YBD=2360 YHG=2316>anxiety " XBD=2258 XHG=2191 YBD=2350 YHG=2327>are " XBD=2411 XHG=2284 YBD=2350 YHG=2315>found " XBD=2607 XHG=2437 YBD=2350 YHG=2316>between" XBD=1496 XHG=1425 YBD=2399 YHG=2364>the " XBD=1648 XHG=1530 YBD=2399 YHG=2368>acute " XBD=1852 XHG=1674 YBD=2399 YHG=2365>neurosis " XBD=2027 XHG=1881 YBD=2410 YHG=2365>arising " XBD=2096 XHG=2054 YBD=2399 YHG=2365>in " XBD=2192 XHG=2122 YBD=2399 YHG=2364>the " XBD=2349 XHG=2220 YBD=2399 YHG=2364>stable " XBD=2606 XHG=2380 YBD=2401 YHG=2365>combatant" XBD=1514 XHG=1424 YBD=2447 YHG=2413>who " XBD=1620 XHG=1546 YBD=2447 YHG=2413>has " XBD=1911 XHG=1652 YBD=2458 YHG=2414>experienced " XBD=2054 XHG=1942 YBD=2459 YHG=2417>great " XBD=2207 XHG=2087 YBD=2448 YHG=2417>stress " XBD=2320 XHG=2239 YBD=2448 YHG=2414>and " XBD=2422 XHG=2352 YBD=2448 YHG=2414>the " XBD=2606 XHG=2455 YBD=2448 YHG=2413>chronic" XBD=1635 XHG=1425 YBD=2496 YHG=2462>abnormal " XBD=1739 XHG=1655 YBD=2496 YHG=2461>fear " XBD=1866 XHG=1761 YBD=2496 YHG=2465>state " XBD=1980 XHG=1888 YBD=2496 YHG=2474>seen " XBD=2042 XHG=2000 YBD=2496 YHG=2463>in " XBD=2132 XHG=2062 YBD=2496 YHG=2463>the " XBD=2283 XHG=2153 YBD=2504 YHG=2463>timid, " XBD=2505 XHG=2306 YBD=2504 YHG=2462>unstable, " XBD=2605 XHG=2526 YBD=2508 YHG=2472>per-" XBD=1525 XHG=1423 YBD=2557 YHG=2511>haps " XBD=1779 XHG=1553 YBD=2553 YHG=2511>backward, " XBD=1902 XHG=1806 YBD=2546 YHG=2523>man " XBD=2028 XHG=1928 YBD=2546 YHG=2511>who " XBD=2191 XHG=2044 YBD=2546 YHG=2515>cannot " XBD=2357 XHG=2218 YBD=2556 YHG=2512>adjust " XBD=2543 XHG=2382 YBD=2547 YHG=2511>himself " XBD=2604 XHG=2564 YBD=2547 YHG=2515>to" XBD=1494 XHG=1423 YBD=2595 YHG=2561>the " XBD=1667 XHG=1516 YBD=2606 YHG=2561>change " XBD=1790 XHG=1687 YBD=2595 YHG=2560>from " XBD=1973 XHG=1813 YBD=2595 YHG=2560>civilian " XBD=2036 XHG=1993 YBD=2595 YHG=2564>to " XBD=2215 XHG=2058 YBD=2595 YHG=2560>Service " XBD=2321 XHG=2235 YBD=2596 YHG=2561>life." XBD=1681 XHG=1474 YBD=2658 YHG=2617>TORRIE,18 " XBD=1851 XHG=1694 YBD=2662 YHG=2617>writing " XBD=1906 XHG=1862 YBD=2651 YHG=2628>as " XBD=1942 XHG=1918 YBD=2651 YHG=2629>a " XBD=2240 XHG=1956 YBD=2662 YHG=2617>psychologist, " XBD=2402 XHG=2259 YBD=2652 YHG=2617>classes " XBD=2605 XHG=2419 YBD=2662 YHG=2627>exposure" XBD=1467 XHG=1423 YBD=2701 YHG=2669>to " XBD=1519 XHG=1494 YBD=2700 YHG=2678>a " XBD=1672 XHG=1545 YBD=2700 YHG=2666>direct " XBD=1833 XHG=1698 YBD=2700 YHG=2666>threat " XBD=1904 XHG=1860 YBD=2700 YHG=2670>to " XBD=1998 XHG=1929 YBD=2701 YHG=2665>life " XBD=2068 XHG=2024 YBD=2700 YHG=2678>as " XBD=2164 XHG=2094 YBD=2700 YHG=2666>the " XBD=2301 XHG=2190 YBD=2701 YHG=2667>main " XBD=2603 XHG=2327 YBD=2712 YHG=2667>precipitating" XBD=1566 XHG=1422 YBD=2750 YHG=2715>factor. " XBD=1780 XHG=1620 YBD=2760 YHG=2715>Change " XBD=1915 XHG=1812 YBD=2750 YHG=2714>from " XBD=1971 XHG=1947 YBD=2749 YHG=2727>a " XBD=2092 XHG=2003 YBD=2749 YHG=2715>unit " XBD=2216 XHG=2118 YBD=2749 YHG=2715>with " XBD=2353 XHG=2248 YBD=2760 YHG=2716>good " XBD=2601 XHG=2384 YBD=2760 YHG=2715>leadership" XBD=1466 XHG=1422 YBD=2799 YHG=2768>to " XBD=1566 XHG=1491 YBD=2799 YHG=2776>one " XBD=1687 XHG=1589 YBD=2801 YHG=2765>with " XBD=1735 XHG=1711 YBD=2798 YHG=2776>a " XBD=1890 XHG=1757 YBD=2799 YHG=2763>leader " XBD=2001 XHG=1912 YBD=2799 YHG=2764>who " XBD=2093 XHG=2023 YBD=2798 YHG=2764>did " XBD=2187 XHG=2115 YBD=2798 YHG=2767>not " XBD=2358 XHG=2210 YBD=2809 YHG=2764>inspire " XBD=2604 XHG=2382 YBD=2799 YHG=2764>confidence" XBD=1503 XHG=1421 YBD=2848 YHG=2825>was " XBD=1554 XHG=1529 YBD=2848 YHG=2825>a " XBD=1727 XHG=1581 YBD=2848 YHG=2814>second " XBD=1975 XHG=1752 YBD=2858 YHG=2813>important " XBD=2118 XHG=2003 YBD=2847 YHG=2824>cause " XBD=2190 XHG=2145 YBD=2847 YHG=2813>of " XBD=2454 XHG=2211 YBD=2848 YHG=2812>breakdown " XBD=2520 XHG=2479 YBD=2847 YHG=2814>in " XBD=2601 XHG=2544 YBD=2847 YHG=2812>his" XBD=1545 XHG=1424 YBD=2898 YHG=2874>cases. " XBD=1706 XHG=1601 YBD=2898 YHG=2863>Over " XBD=1821 XHG=1725 YBD=2907 YHG=2862>90% " XBD=1888 XHG=1842 YBD=2897 YHG=2861>of " XBD=1961 XHG=1899 YBD=2897 YHG=2862>his " XBD=2080 XHG=1980 YBD=2897 YHG=2863>2500 " XBD=2275 XHG=2098 YBD=2907 YHG=2863>patients " XBD=2395 XHG=2294 YBD=2897 YHG=2874>were " XBD=2530 XHG=2413 YBD=2897 YHG=2863>timid " XBD=2600 XHG=2550 YBD=2906 YHG=2863>by" XBD=1579 XHG=1420 YBD=2953 YHG=2915>nature, " XBD=1747 XHG=1607 YBD=2956 YHG=2911>nearly " XBD=1861 XHG=1771 YBD=2946 YHG=2911>half " XBD=1929 XHG=1884 YBD=2946 YHG=2911>of " XBD=2063 XHG=1951 YBD=2946 YHG=2911>them " XBD=2189 XHG=2089 YBD=2945 YHG=2923>were " XBD=2343 XHG=2216 YBD=2946 YHG=2911>below " XBD=2535 XHG=2369 YBD=2956 YHG=2923>average " XBD=2603 XHG=2561 YBD=2945 YHG=2911>in" XBD=1669 XHG=1418 YBD=3005 YHG=2960>intelligence " XBD=1771 XHG=1690 YBD=2994 YHG=2961>and " XBD=2018 XHG=1791 YBD=3001 YHG=2960>education, " XBD=2120 XHG=2040 YBD=2994 YHG=2960>and " XBD=2166 XHG=2142 YBD=2993 YHG=2972>a " XBD=2295 XHG=2185 YBD=2994 YHG=2960>third " XBD=2361 XHG=2316 YBD=2994 YHG=2960>of " XBD=2487 XHG=2376 YBD=2994 YHG=2960>them " XBD=2601 XHG=2508 YBD=2994 YHG=2969>were" XBD=1519 XHG=1418 YBD=3053 YHG=3009>aged " XBD=1718 XHG=1538 YBD=3043 YHG=3009>between " XBD=1789 XHG=1742 YBD=3043 YHG=3010>30 " XBD=1895 XHG=1814 YBD=3043 YHG=3009>and " XBD=1967 XHG=1919 YBD=3043 YHG=3010>50 " XBD=2116 XHG=1991 YBD=3052 YHG=3020>years. " XBD=2431 XHG=2172 YBD=3050 YHG=3008>GARMANY,19 " XBD=2600 XHG=2451 YBD=3052 YHG=3009>writing" XBD=1464 XHG=1418 YBD=3091 YHG=3057>of " XBD=1648 XHG=1471 YBD=3091 YHG=3058>reactive " XBD=1875 XHG=1661 YBD=3102 YHG=3057>anxiety in " XBD=2009 XHG=1887 YBD=3091 YHG=3057>naval " XBD=2185 XHG=2021 YBD=3101 YHG=3057>ratings, " XBD=2288 XHG=2200 YBD=3102 YHG=3057>lays " XBD=2403 XHG=2296 YBD=3091 YHG=3056>chief " XBD=2602 XHG=2412 YBD=3102 YHG=3057>emphasis" XBD=1470 XHG=1418 YBD=3140 YHG=3118>on " XBD=1632 XHG=1504 YBD=3151 YHG=3117>group " XBD=1797 XHG=1660 YBD=3147 YHG=3118>sense ; " XBD=1870 XHG=1835 YBD=3139 YHG=3105>if " XBD=1973 XHG=1892 YBD=3140 YHG=3106>this " XBD=2090 XHG=2001 YBD=3140 YHG=3105>fails " XBD=2161 XHG=2117 YBD=3140 YHG=3117>as " XBD=2212 XHG=2189 YBD=3140 YHG=3118>a " XBD=2364 XHG=2239 YBD=3141 YHG=3105>result " XBD=2439 XHG=2394 YBD=3140 YHG=3104>of " XBD=2601 XHG=2464 YBD=3141 YHG=3106>consti-" XBD=1593 XHG=1417 YBD=3189 YHG=3155>tutional " XBD=1855 XHG=1637 YBD=3189 YHG=3155>limitation " XBD=1942 XHG=1899 YBD=3189 YHG=3167>or " XBD=2202 XHG=1988 YBD=3189 YHG=3155>traumatic " XBD=2490 XHG=2249 YBD=3200 YHG=3155>experience, " XBD=2599 XHG=2536 YBD=3189 YHG=3155>the" XBD=1623 XHG=1416 YBD=3237 YHG=3203>threshold " XBD=1712 XHG=1650 YBD=3238 YHG=3203>for " XBD=1905 XHG=1740 YBD=3248 YHG=3204>anxiety " XBD=2021 XHG=1931 YBD=3238 YHG=3203>falls " XBD=2133 XHG=2052 YBD=3238 YHG=3204>and " XBD=2177 XHG=2153 YBD=3237 YHG=3215>a " XBD=2379 XHG=2202 YBD=3238 YHG=3205>neurosis " XBD=2599 XHG=2407 YBD=3249 YHG=3203>develops." XBD=1593 XHG=1416 YBD=3286 YHG=3252>Because " XBD=1655 XHG=1622 YBD=3286 YHG=3252>it " XBD=1716 XHG=1683 YBD=3285 YHG=3252>is " XBD=1761 XHG=1738 YBD=3286 YHG=3264>a " XBD=1875 XHG=1788 YBD=3286 YHG=3264>new " XBD=2016 XHG=1901 YBD=3297 YHG=3252>thing " XBD=2090 XHG=2047 YBD=3287 YHG=3256>to " XBD=2240 XHG=2118 YBD=3296 YHG=3254>speak " XBD=2427 XHG=2266 YBD=3296 YHG=3252>frankly " XBD=2498 XHG=2454 YBD=3286 YHG=3252>of " XBD=2636 XHG=2520 YBD=3292 YHG=3252>fear" XBD=1459 XHG=1415 YBD=3334 YHG=3311>as " XBD=1639 XHG=1486 YBD=3345 YHG=3300>part of " XBD=1680 XHG=1656 YBD=3334 YHG=3312>a " XBD=1963 XHG=1696 YBD=3334 YHG=3300>combatant’s " XBD=2063 XHG=1983 YBD=3341 YHG=3300>life, " XBD=2340 XHG=2080 YBD=3347 YHG=3301>euphemistic " XBD=2486 XHG=2361 YBD=3335 YHG=3300>labels " XBD=2599 XHG=2502 YBD=3334 YHG=3301>have

17. Lancet, 1943, ii, 785.18. Torrie, A, Ibid, Jan. 29, p. 139.19. Garmany, G. Ibid, Jan. 1, 1944, p. 7.