coquí pharma - etec · coquí’s mission is to create a commercially scalable and reliable supply...
TRANSCRIPT
Leadership Presentation atNuclear Suppliers Workshop
Coquí Pharma
Oak Ridge, TN2 October, 2018
Carmen Bigles Coquí CEO & President
Introduction
“Only a life lived for others is a life worthwhile”
~ Albert Einstein ~
The impact of having a sustainable supply of medical radioisotopes particularly Mo-99 will advance medicine.
Coquí’s mission is to create a commercially scalable and reliable supply of medical diagnostic and therapeutic
radioisotopes in the US using proven technology
2October 2018
Nuclear Reactors to Healthcare
COMPANY CONFIDENTIAL 3
Mo-99 is an essential part of modern nuclear medicine• Mo-99’s (Molybdenum-99) decay product, Technetium-99m (Tc-99m) is utilized in over 80% of all
SPECT nuclear medicine procedures, it is the world’s most widely used medical radioisotope
• Annually over 18 million procedures in the United States utilize Mo-99 (most Myocardial perfusion studies)
• Mostly produced from weapons grade U-235 (i.e., Highly Enriched Uranium or HEU)
• USA is the largest global Consumer yet no domestic manufacturing capability
U235 in Reactor for irradiation
Mo99 Separated & Purified
Tc99m
GeneratorRadiopharmacy Patient
October 2018
The Coquí Solution
COMPANY CONFIDENTIAL 4
• Proven 10MW Nuclear Reactor from INVAP Exclusive license for USA from INVAP: the world’s leading designer
and developer of LEU Mo-99 production facilities CNEA Mo-99 Technology OPAL in Australia, Egypt, Argentina, Algeria & Netherlands* All Low Enriched Uranium (LEU)
• Proven FDA approved LEU Mo-99 process Meet >50% of USA Medical Demand 50% domestic and 50% export
• Coquí Project $500M CAPEX facility 1,500 construction jobs 150 permanent high-tech jobs Nuclear collaborative opportunities with ORNL U-235 for target plates & fuel assemblies from Y-12 Future Heritage Center Airport
October 2018
The Ideal Site for Coqui
Criteria
5
USA Nuclear Centre of Excellence
Strong nuclear talent pool
Nuclear strategic- collaborative opportunities & partnerships
Understanding nuclear friendly community
Supply of U-235 for Fuel & Targets
Nuclear waste processing capability
Emergency & Hazmat Services
Airport close by
Security perimeter with one access point…. an island
October 2018
Strategic Site Location - I
The Coquí to be strategically located at Oak Ridge, Tennessee
6October 2018
Strategic Site Location - II
ETTP & Heritage Center
7
• Oak Ridge (1942) comprised Y-12, S-50, K-25 & X-10 facilities and was known as the Manhattan Project
• Used to produce enriched Uranium using the gaseous diffusion method at K-25
• Today Oak Ridge hosts one of the largest National Labs for Science & Energy in the USA
• Original home of some medical radioisotopes
• Nuclear Technology Park• Former Manhattan Site• Heritage Center
• Strategic location for Coquí Centre for USA Nuclear Excellence Nuclear collaborative opportunities Understanding nuclear friendly community Strong nuclear talent pool Nuclear waste processing Y-12 for Fuel & Targets Emergency & Hazmat Services Proactive Economic Development community
October 2018
Strategic Site Location - III
Coqui’s new home at Oak Ridge
October 2018 8
• Duct Island
• 206 Acres Greenfield site
• 101,337 SqFt (2.3 Acres)
• Road, air & water access
• Geotechnical surveys by DOE
• Water security perimeter
• Multiple electricity sources
• TVA SMR neighbour
Strategic Site Location - IV
Proposed Airport at Oak Ridge
9
• Minutes from Duct Island
• 5,000 foot runway
• Suitable for Type A & Type B(U) transport containers
• $35-40M
• Operational in 2022
• Gross Margin advantage due to close proximity
• Awaiting approval by FAA
• Backup: RKW (30 mins) & TYS (42 mins)
www.oakridgeairport.org
October 2018
Breaking News……
Coqui’s new home is now a reality………..
10October 2018
Thank You
October 2018 11
World class team
National Critical Infrastructure
Proven Technology
Oak Ridge
The specific discussions herein about our company include financial projections and
future estimates and expectations about the company’s business. The projections,
estimates, and expectations are presented only as a guide about future possibilities
and do not represent actual amounts or assured events. All the projections and
estimates are based exclusively on our company management’s own assessment of
its business, the industry in which it works, the economy at large, and other
operational factors, including capital resources and liquidity, financial condition,
fulfillment of contracts, and opportunities. Potential investors should not make an
investment decision based solely on our company’s projections, estimates, or
expectations.
October 2018 12