corrigendum corrigendum to evaluating the importance of the...

CorrigendumCorrigendum to (Evaluating the Importance ofthe Carotid Chemoreceptors in Controlling Breathingduring Exercise in Man)

M. J. Parkes

School of Sport, Exercise & Rehabilitation Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK

Correspondence should be addressed to M. J. Parkes; [email protected]

Received 18 June 2015; Accepted 25 June 2015

Copyright © 2015 M. J. Parkes. This is an open access article distributed under the Creative Commons Attribution License, whichpermits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

In the paper titled “Evaluating the Importance of the CarotidChemoreceptors in Controlling Breathing during Exercise inMan,” please note that in Figure 4(a) the top scale should readas follows: Equivalent altitude (k ft) calculated byDripps (andnot km).

Hindawi Publishing CorporationBioMed Research InternationalVolume 2015, Article ID 969257, 2 pageshttp://dx.doi.org/10.1155/2015/969257

2 BioMed Research International

Oxygen in inspired gas (%)

Number of subjects

0 5 10 15 20 25

40

30

20

10

100 20.9 18 16 14 12 10 8 6 4

500

400

300

200

100

102 80 66 51 40

55 156 14 36 20 11 66 56

11

9

18

20

Nor

mal

resp

irato

rym

inut

e vol

ume (

%)

Resp

irato

ry m

inut

evo

lum

e (L/

min

)

Estimated equivalent PaO2 (mmHg)

Equivalent altitude (k ft) calculated by Dripps

(a)

20

18

16

12

8

4

32 34 36 38 40 42 44 46 48 50 52 54 56 58 60 62

PaCO2 (mmHg)

5.5% CO2

4.3% CO2

2.2% CO2

Air

±1 se from mean respiratory minute volume

Ventilation (LBTPS·min−1)

(b)

Figure 4: (a) Relative insensitivity of breathing at rest to artificially lowering PO2in Man. Minute ventilation (± se solid bars, ± sd open

bars) in normal subjects [87] as inspired oxygen is artificially lowered (strictly hypocapnic hypoxia exists once hyperventilation occurs).Equivalent PaO

2points are aligned on the FiO

2scale, with PaO

2estimated before hyperventilation occurs using the alveolar gas equation

(assuming 760mmHg barometric pressure, RQ = 0.8, PaO2= PAO

2, and PaCO

2= PACO

2), and the point afterwards is estimated based on

dynamic forcing experiments in isocapnia (courtesy of Dr. G. A. Balanos). Reproducedwith permission fromDripps et al., [87]. (b) Sensitivityof breathing at rest to artificially raising PaCO

2in Man. Minute ventilation and PaCO

2(femoral) in 8 healthy men [88] while inhaling 0–6%

CO2in air at atmospheric pressure (mean slope is 2.5 L⋅min−1mmHg−1 artificial PaCO

2rise). Reproduced with permission from Lambertsen

et al. [88].

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