course 10 global burden of disease: impact of vision loss contribution of the gbd and dissemination...
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Course 10Global Burden of Disease:
Impact of Vision Loss
Contribution of the GBDand dissemination of results
Serge Resnikoff MD, PhDOn behalf of the GBD Vision Loss Expert Group
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Why do we need data?
• 1. To support Advocacy
“Advocacy is the process of influencing decision-makers to create change”
• Requires best possible information for
– making effective policy decisions
– mobilizing more resources
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Why do we need data?
• 2. To support priority setting, planning, monitoring and evaluation
• Especially for quantifying how much needs to be prevented and treated
• Implies:– cause-specific data– country level data– periodically updated data– comparable data over time for trends analysis
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In the Past
• WHO/PBD Data Bank, initiated by AD Negrel.– Two closets in a
corridor – Two papers published:
lists of publications
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WHO/PBD Data Bank
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In the Past
• WHO/PBD Data Bank, initiated by AD Negrel.– Two closets in a corridor – Two papers published: lists of publications– 2006: attempt of integration in the WHO InfoBase
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In the Past
• WHO/PBD Data Bank, initiated by AD Negrel.– Two closets in a corridor – Two papers published: lists of publications– 2006: attempt of integration in the WHO InfoBase
• Used to generate periodic “global (and regional) estimates of Blindness and Visual impairment”– 1970, 1976, 1990– 1996, 2002, 2004, 2008, 2010
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Contribution
• WHO Global Estimates– initially used for the first GBD exercise– then used to feed the WHO annual statistical
report (part of World Health Report) – till 2004
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1996
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1990 (WDR 1993)
Sense Organ Cataract Glaucoma
VAD
Oncho
Trachoma
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W
WHR 2003GlaucomaCataractVision loss, age related and other
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Contribution
• WHO Global Estimates– major role in the genesis of V2020 (avoidable
blindness, trends due to ageing, magnitude of URE)– Mainly used for advocacy and communication
• Previous GBD data (1990/96, GBD 2004)– Based on WHO/PBD estimates– high impact on Cost Effectiveness analysis (cataract,
oncho, VAD…)– major role in “ranking” VI against other conditions
(issue of groupings)
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GBD 2001 (2006)
Top 10 Causes of Years Lived with Disability
24
63 2
4
CataractVision disorders, Age-related
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Second Edition (2006)
CataractGlaucomaTrachomaOnchocerciasisOther
3.2% of total DALYs
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Major issue: data are not directly comparable
Resnikoff & Keys, IJO 2012
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How do the findings differ?
1990 20100
5
10
15
20
25
30
35
40
Blind
WHO/PBD GBD
1990 20100
50
100
150
200
250
300
MSVI
WHO/PBD GBD
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Dissemination challenges:What is needed?
• country level data (prevalence and causes) for advocacy, priority setting, planning and monitoring.
• data easy to understand and visualize
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Visualisation
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Dissemination challenges:What is needed?
• country level data (prevalence and causes)• data easy to understand and visualize• data easy to access and use (web based)• data regularly updated (as for mortality or
demographic data) – implies specific resources and organization
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Dissemination: Publication plan
• Published:Editorial: Global Burden of Visual Impairment and Blindness. Bourne R, Price H, Stevens G. Arch Ophthalmol. 2012;130(5):645-647. • Accepted for publication :The Global Burden of Disease Project: Rationale and Methodology of the Systematic Review by the Vision Loss Group. Bourne R, Price H, Taylor H, Leasher J, Keeffe J, et al. Ophthalmic Epidemiology. Accepted 1 Sept 2012.• Submitted:Global Prevalence of Vision Impairment and Blindness: Magnitude and Temporal Trends, 1990-2010. Stevens G, White R, Flaxman S, Price H et al. PLoS Medicine
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Dissemination: Publication plan
• Planned:– Cause specific data – at global level– Regional papers combining causes with prevalence of
Vision Impairment and Blindness
• Also capstone papers from the GBD Core group on:– Disability Weights– DALYs.
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Plan for the Future (5 years)
1. Maintain the global data base and provide periodic updates:– Update the database by annual extensions of the systematic review – Release an interim update in 2014/15. – Revisit the statistical model and provide a 5 year update in 2017 .
2. Create an internet-based portal to:– provide access to population-based prevalence data by age, by sex, by
region, by country, and by cause.– model the data temporally, both retrospectively and prospectively.– also provide additional parameters such as GDP and other metrics to
develop visualisations.
• Project is supported by BHVI