ct applications in chest pathology

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    CT Applications in Chest Pathology

    Objectives are as follows,

    • List the types of CT

    • List the indications of chest CT

    • Understand the applications of chest CT

    • Identify the radiological signs of common chest diseases on CT

    Basics of CT

    •  Two dimensional representation of a three dimensional slice

    • Internal structure of the organ can be reconstructed from multiple slices

    Image display settings can be varied by adjusting WW & WL

    Lung window

    Mediastinal window soft tissue window!

    "one window

    Types of CT Scans are,

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    • Conventional CT

    • #igh resolution CT

    Conventional CT Vs HRCT 

    • Conventional$ % to ' mm thic( slices are obtained contiguously) imaging''* of the lung

    • HRCT$ $+,mm thin slices of lung are obtained at non$contiguous intervals)

    usually to - cm apart) throughout the whole lung+ + .nly , to '* of the

    lung is sampled

    Indications of Chest CT 

    • /valuation of an abnormality identi0ed on conventional radiographs $ 1olitary

    pulmonary nodule2 lung tumour2mediastinal mass

    • 3iagnosing & 1taging of Lung Cancer

    • 3etection of occult pulmonary metastases

    • 3etection of mediastinal nodes 2masses

    • 3istinction of empyema from peripheral lung abscess

    • 3etection and evaluation of aortic disease

    • 4ulmonary embolism

    • #aemoptysis

     Applications of CT 

    1 !etection of "#n$ T#%o#rs-+ 3iagnosis%+ 5natomic e6tent of disease $Intra and2or e6tra thoracic disease e6tent ) T7M

    descriptors8+ 3ecision of therapeutic strategy $1urgery $vs$ Chemotherapy $vs$ 4alliative

    Care 9esectability 2 Irresectability,+ Image guided biopsies

    Lung tumours

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    "enign tumours $ #armatoma) 5denoma) 5: Malformation

    Malignant tumours$ 4rimary "ronchial Ca) 5lveolar cell Ca!) 1econdary

    Beni$n t#%o#rs& Har%ato%a

    • '( of all solitary p#l%onary nod#les are har%ato%as

    • It is the %ost co%%on beni$n l#n$ t#%o#r

    •  They are %ostly asy%pto%atic

    Har%ato%a

    • 9ound) smooth mass $ increase in si;e slowly

    • Calci0cation in ,* $ pathognomonic if popcorn type

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    + 5ssess the primary tumour

    -+ 5ssess the secondary e>ect 2complications

    %+ 5ssess the nodal2 other metastasis

    CT appearances in pri%ary %ali$nant t#%o#r

    + 3ense irregular hilar opacity

    -+ 3ense peripheral opacity

    %+ 3ense irregularly cavitating lesion

    8+ #ilar opacity with collapse of a segment 2whole lung

    *ali$nant t#%o#r&Secondary e+ects

    + 4leural e>usion

    -+ Mediastinal widening

    %+ .steolytic lesions of the rib

    8+ 3iaphragmatic paralysis

    !etection of "#n$ Cancer lain Radio$raphy vs CT 

    • Contrast resolution of CT is superior  to plain chest radiography

    •  1igni0cantly more nodules detected on CT

    The Stages of Lung Cancer

    1tage I -o nodal %etastases and s#r$ically re%ovable 

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    • 1tage II  )dds hilar ly%ph node involve%ent .II)/ or resectable chest

    wall0%ediastinal involve%ent .IIB/

    • 1tage III 5 2tensive b#t resectable disease

    • 1tage III " 2tensive b#t irresectable by conventional criteria b#t still

    con3ned to chest, therefore consider radical radiotherapy 

    • 1tage I: !istant %etastases

    The Staging of Lung Cancer: International Staging System

    PRIMARY TUMUR !T"

    •  T !ia%eter ≤ 4c%s, s#rro#nded by l#n$ 0visceral ple#ra -o involve%ent of

    lobar bronchi

     T-54c% dia%eter6 involves %ain bronch#s b#t≥

     7c% distal to carina6 invadesvisceral ple#ra6 associated with atelectasis or obstr#ctive pne#%onitis e2tendin$ to

    hila b#t not involvin$ entire l#n$

    • T#T#%o#r of any si8e b#t with invasion of9 chest wall,diaphra$%, %ediastinal ple#ra

     parietal ple#ra, parietal pericardi#%, or t#%o#r in %ain bronch#s :7c% fro% carina

    b#t not involvin$ carina6 or atelectasis 0 obstr#ctive pne#%onitis of entire l#n$

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    T2T

    1

    • T$T#%o#r of any si8e b#t with invasion of9 heart, $reat vessels, trachea,

    oesopha$#s, vertebral body, carina6 t#%o#r with %ali$nant ple#ral 0 pericardial

    e+#sion6 or with satellite t#%o#r nod#le.s/ in ipsilateral pri%ary&t#%o#r lobe

    The CT Staging of Lung Cancer? T1 vers#s T7 lesions

    The CT Staging of Lung Cancer? T1 0 T7 lesions

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    The CT Staging of Lung Cancer? T4 0 T; lesions

     

     T%

    S#perior s#lc#s t#%o#rs

     

    The CT Staging of Lung Cancer? -odal Sta$in$

    • 7. -one

    • 7 Ipsilateral hilar

    • 7- Ipsilateral %ediastinal .incl s#bcarinal/

    • 7% Contralateral %ediastinal 0 hilar or s#praclavic#lar

    %etection of Lung Cancer& BIOS

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    *etastases in "#n$ Cancer 

     

    "iver  %%$%*

     )drenals -'$%%*

    Brain D$-D*

    Bone ,$-*

     Key point 

    CT remains the mainstay in the non$invasive staging of lung cancerE

    Mediastinal masses

    • 57T/9I.9 M/3I51TI7UM

     T#FM.M5

     T/95T.M5

    I7T95T#.95CIC T#F9.I3 /7L59G/M/7T

    LFM4#.M5 !# T's an( an L"

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     .T#/9 $ LFM4#57GI.M5

      57/U9F1M .< 51C/73I7G 5.9T5

    *iddle %ediastini#% = *asses

    • Merge with hilae and cardiac borders

    • Lymphadenopathy

    • "ronchogenic cyst

    • 5ortic aneurysm

    • Most middle mediastinal masses are due to enlarged nodes+

    osterior %ediastinal %asses

    7eurogenic tumour

    • /6tramedullary haemopoeisis

    • 9eticulosis) myeloma

    • 4aravertebral abscess

    •  /nlarged paravertebral lymph nodes

    • #aematoma following injury to the spine

    • 5ortic aneurysm

    • #iatus hernia

    • 3ilated oesophagus in achalasia

    Thy%o%a = CT 

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    Retrosternal $oiter 

     

    Commonest pleural masses

    • Mesothelio)a: It is a di>use or localised pleural mass+ Large pleural e>usions are

    common+ May have associated pleural pla=ues

    • Pleural )etastases $ often obscured by the accompanying e>usion

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    *ali$nant %esothelio%a

    "#n$ )bscess

     )ortic ane#rys%

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    #l%onary e%bolis%

    In(ications of Chest HRCT

    • 3etection of lung disease in patient with pulmonary signs and symptoms or

    abnormal pulm function test but normal or e=uivocal CH9

     –  /mphysema) /6trinisic allergic alveolitis) small airway disease)

    immunocompromised patient

    • /valuation of di>usely abnormal CH9

     –  Cystic 0brosis) 1arcoidosis) interstitial lung disease #istocytosis H) 5931

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    HRCT -or%al l#n$

    Basic HRCT Patterns

    • Lines

    • 7odules

    • Consolidation

    • Ground$glass .pacity

    • Cysts

    Linear a*nor)alities

    a! thic(ened interlobular septa

    b! bronchovascular interstitial thic(ening

    c! reticular change

      e+g

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    >ibrosin$ alveolitis

    "y%phan$itic t#%o#r 

    -od#les

    • 5 nodule is a rounded density that does not correspond to a vessel+

    •  The anatomic distribution of nodules$$centrilo*ular) ran(o)) or interstitial$$helps

    to identify potential causes

      e+g$ bronchopneumonia gives nodules in a centrilobular distribution

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    -od#les = Infective

    ?ro#nd $lass opacity 

    • 5 ha;y opacity that does not obscure the associated pulmonary vessels+ This

    appearance results from parenchymal abnormalities that are below the spatial

    resolution of #9CT+

    • /+g+ alveolar wall inammation or thic(ening) with partial air$space 0lling) or with

    some combination of the two+

    ?ro#nd $lass& In@#en8a pne#%onia

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    Cysts

    • 9ounded structure that is 0lled with air and usually has a thin wall+

    •  The cyst contents are as dar( as air surrounding the patient

    • /+g+Cystic bronchiectasis

    Chronic interstitial 0brosis subpleural honeycombing!

      LangerhanJs cell #istiocytosis

    Lymphangioleiomyomatosis

    Cystic Bronchiectasis

    Consolidation