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CURRICULUM VITAE BRIAN LEIF HJELLE

MARCH 2012

PERSONAL DATA: Mailing Address: Shipping Address: Department of Pathology, 329 CRF Department of Pathology, 329 CRF School of Medicine School of Medicine MSC08 4640 915 Camino de Salud NE 1 University of New Mexico Albuquerque, NM 87131 Albuquerque, NM 87131-5301 Telephone: (505) 272-0624 (W) Fax: (505) 272-4401 Email, Internet Addresses: bhjelle@salud.unm.edu http://hsc.unm.edu/research/facultyprofiles/index.cfm ?m=main.faculty&unique_id=685BABBDC47011E3 CA95EA1FEAC2C5AE EDUCATION AND TRAINING: A.B. 1978 University of California, Berkeley - Major: Biochemistry M.D. 1983 Johns Hopkins University School of Medicine Jan 1981-Jan 1982: Laboratory Associate Pediatrics Genetics Division-John Phillips Lab Johns Hopkins University School of Medicine Jul 1983-Jun 1984: Resident in Internal Medicine Eastern Virginia Graduate School of Medicine Jul 1984-Dec 1984: Postdoctoral Fellow Department of Microbiology and Immunology-K. Somers Lab Eastern Virginia Medical School

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Jan 1985-Jun 1987: Postdoctoral Fellow The G.W. Hooper Foundation-J. Michael Bishop Lab University of California, San Francisco Jul 1987-Jun 1988: Resident in Laboratory Medicine University of California, San Francisco Jul 1988-Jun 1989: Chief Resident in Laboratory Medicine University of California, San Francisco ACADEMIC APPOINTMENTS: Jul 1989-1997: Associate Medical Director, United Blood Services Albuquerque, NM Jul 1989-Jun 1995: Assistant Professor of Pathology University of New Mexico School of Medicine Jul 1995- Jun 2001: Associate Professor of Pathology University of New Mexico School of Medicine Apr 1997- July 2001: Adjunct Associate Professor of Molecular Genetics and Microbiology University of New Mexico School of Medicine Sep 1997- July 2001: Adjunct Associate Professor of Biology University of New Mexico Dec 1997- Present: Associate Director, Molecular Diagnostics Core Laboratory Now Genetics and Cytometry Laboratory University of New Mexico Hospital/TriCore Corp. Jul 2001-Present: Professor of Pathology Adjunct Professor of Molecular Genetics and Microbiology Adjunct Professor of Biology Instructor, MPH Program University of New Mexico May 2002-Oct 2009: Vice Chair for Research Department of Pathology, UNM School of Medicine Jul 2006-Aug 2008: Interim Chair Department of Pathology, UNM School of Medicine

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HONORS (SELECTED): Phi Beta Kappa Valedictorian, Biochemistry, UC Berkeley 1978 Departmental Citation in Biochemistry Research, 1977-78 Departmental Honors in Biochemistry Research Henry Strong Denison Award for Medical Research, 1980 March of Dimes Award for Birth Defects Research, 1980 Peder P. Johnson Scholar, 1980, 1982 Western Association of Physicians Distinguished Lecturer Award, 1993 Commendation from New Mexico Governor Bruce King, 8 Oct 1993 Department of Biochemistry Annual Faculty Speakers Award, 1999 Dean's Award of Distinction, UNM School of Medicine, February 1999 Dean's Award of Distinction, UNM School of Medicine, March 2000 Los Alamos National Laboratory Achievement Award, Apr 2000 Dean's Award of Distinction, UNM School of Medicine, February 2001 WHO Consultant for Hemorrhagic Fever, China, Nov 2003 Translational Research/Inventors Award, UNM HSC, April 2004 Collaborating scientist in Chief Scientist’s Award for Excellence Mar 2006, Defense Intelligence Agency MASINT Fellow, College of American Pathologists, October 2006 Albuquerque The Magazine: nominated for “Top Doc” Pathology, 2007 Invited Distinguished Member, “One Health” Program, 2007 R&D 100 Award 2010 for “Ligand-Based Biosensor for Detection of Microbes” MENTIONED IN: Science (journal) 30 Jul 2004; 305: 605 31 Jan 1997; 275: 605 15 May 1998; 280: 993 16 Aug 1996; 273: 863 21 Mar 2003; 299: 1822 6 Jul 2001; 293: 24-5 26 May 2000; 288: 1320-2 16 Jul 1999; 285: 347-8 5 Nov 1993; 262: 832-836 and 836-8 LANGUAGES:

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English Spanish OTHER PROFESSIONAL APPOINTMENTS, INCLUDING HOSPITAL APPOINTMENTS: Mar 1977-Jun 1978: Laboratory Assistant Department of Biochemistry-Bruce Ames Lab University of California-Berkeley Aug 1989- Present: Clinical Privileges at University Hospital, Albuquerque LICENSURE AND CERTIFICATION: July 1984: Diplomate, National Board of Medical Examiners Sept 1990: Diplomate, American Board of Pathology (Clinical Pathology) 1985: California Medical License 1989: New Mexico Med. License GOVERNMENT SERVICE: 1993-1996: Member, Hantavirus Pulmonary Syndrome Clinical Trial Committee for National Institute of Allergy and Infectious Diseases, National Institutes of Health (Collaborative Antiviral Study Group) Mar 25, 1993: Presentations to Blood Products Advisory Committee Meeting, U.S. Food and Drug Administration "HTLV-II: Association with Neurologic Disease" "Sensitivity of HTLV-I Screening Tests for HTLV-II Antibodies” TEACHING AND EDUCATIONAL ACTIVITIES: Training Completed tutor training workshops, 24 and 26 Oct 1994 Recent Lectures and classroom instruction

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“Failures of Host Defense”, "Viral Immunology" and "HIV Immunopathogenesis" lecture series in Biomedical Sciences 514, Immunobiology, Spring and Fall. “Viral Pathogenesis-I and -II”, and “Emerging Infectious Diseases” (Medical Students) “Introduction to Infectious Diseases”; “Pathogenesis by RNA Viruses” “HIV Immune Escape”, “Hantavirus Pathogenesis”, Biomed Sciences 652 “Immunopathogenesis of Infectious Diseases” Annual lecture for clinical fellows’ core curriculum Instructor, Biomed Sciences 625 Section III, Virology Journal Club (spring 2000-pres) Lecturer, Biology 450, General Virology Lecturer, Anthropology 450-550, Genetics of Human Disease Extramural instructor, Johns Hopkins Univ School of Hygiene and Public Health Medical Microbiology, “Viral immunodiagnostic technologies” 2004-2011 “Intellectual Property”; “Collaborations”; “Mentoring”; “Authorships and Peer Review”; “Managing COI” – Representative lectures provided for Biomedical Research Ethics courses, intra- and extramural, 2000- present Courses Founder and Director or Participant, Biomedical Sciences 652, "Immunopathogenesis of Infectious Diseases", 2000-2010 Director, Biomed 505 section 7, “Translational Research Journal Club” 2011- present Director of 8-lecture Infectious Diseases section of Biomedical Sciences 583, "Topics in Pathology" (Pathology Grand Rounds), 2002- 2007 Co-director and developer of Biomed 555, “Problem-based Research Bioethics”, Spring and Fall semesters, 2000- present Co-director of Clinical and Translational Science Center’s “Bioethics” curriculum Introductory lectures, core Bioethics course for Masters of Science in Clinical Research, Clinical and Translational Sciences, and Global/Geographic Med Programs

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High school students mentorship activities: Mentor to team 66, Goddard HS, Roswell NM, “New Mexico High School

Supercomputing Challenge”, 1997 Aaron Hopkins, Sandia HS, Albuquerque Mentor, Sandia HS Gifted Program Sept 2002 Science fair judging for DoD annual Junior Science and Humanities Fair Apr 28-29, 2006, Albuquerque, NM Undergraduate students mentor: Ray Donaldson, summer, 1994 Julene Moore, summer (comentor), 1996 Robert Nofchissey, summer, (comentor), 1996 Christy Tarleton, January 1997-January 2000 Valerie Bain, January 1998-July 2000 Amanda Leigh Haag (volunteer, summer 1998) Julie Torres (senior honors biochemistry student, summer 1998) Elisabeth Koch (March 2000- August 2000) Melissa Saavedra (July 2000- November 2001) Joel Berger (July 2000-May 2002) Kim Krause (August 2000- July 2001) Marisa Rangel (May 2002- May 2004; senior honors biochemistry student) Tommie Carruthers (May - August 2002, Mesa State College) Mariza Luna (MARC, September 2002 – November 2004) Christopher Schwedes (Cal State Long Beach) May-Aug 2004 Gena McLellan ((IMSD, September 2003 – Mar 2005) Jeff Lucero (MARC, Sept 2004- Oct 2004) Micki Granados (2005-2006) Graduate Student Thesis Advisor: Peggy Moran (1997-1999) Support: NIH RO1 minority supplement Thesis: “Animal Models for Hantavirus Infection”, MS, 2000 Currently: Physician, Santa Fe, NM Jason Botten (1997- 2000) Support: T32 IDIP training grant, NIAID Thesis: “Experimental Infection Model for Sin Nombre Hantavirus in the Deer Mouse (Peromyscus maniculatus): a Novel Approach Yields

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First Insights on the Host-Pathogen Interaction”. PhD, 2000 Currently: Assistant Professor, University of Vermont Funded by NIH NRSA Award 2003-2008 Rafael Medina (2001- 2007). Thesis completed July 2007, Thesis: “Sin Nombre virus-host interactions: In vivo inhibition and viral entry in the deer mouse (Peromyscus maniculatus) model”, PhD, 2007. Currently: Postdoctoral Fellow, Mt. Sinai School of Medicine Laboratory of Adolfo Garcia-Sastre, PhD Joseph Prescott (2001- 2006). Support: T32 IDIP training grant, NIAID Thesis: “Characterization of Human Innate Immune Responses to SNV Infection”. PhD, 2006 Currently: Postdoctoral Fellow, Rocky Mountain Labs, NIAID Laura Darrow Dickson (MS student 2006-2009), MS, 2009 Thesis committee chair, “Epidemiology of Adenovirus Infections” Graduate Students on Rotations: William Hayes (1990) Lee Danielson (1991) Christine Schammel (1992) Gregory Jones (1992) Bruce Anderson (1993) Wendy Green, D.V.M. (1994) Mira Dimitrijevic (1995) Jason Botten (July-September 1996) J.D. Smith (November 1996-January 1997) Peggy Rodriguez-Moran (November 1996-January 1997) Hunter Ahern (August- September 1997) Jennifer Foster (Sept.- November 1998) Karina Gallegos (October - December 1999) Rafael Medina (Sept – Nov 2001) Staci Stolp (Biology) (Sept- Nov 2001) Joseph Prescott (Nov 2001- Feb 2002) Justin Wray (Sept – Dec 2003) Alex Davis (Feb-Apr 2004) Summer Nguyen (May-July 2004) Michele Denton (July-Aug 2005) Hillary Mullins (Nov-Dec 2005) Christina (Sena) Dinkins (Nov 2006- Feb 2007)

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Other Graduate Thesis Committees 1990- 1994: Jacqueline Calvert (J. Summers lab) 1990- 1994: Raymond Lenhoff (J. Summers lab) 1990- 1994: Nitaya Podipleux (C. Willman lab) 1991- 1997: Kristen Steffgen (C. Willman lab) 1994-1997: Andrea Michiner (J. Summers lab) 1998-1999: Wengang Yang (J. Summers lab) 1998-1999: John Robert Herron (C. Wheeler lab) 1998-2003: Chris Allen (J. Nicoloff lab) 2000-2002: Dorie Walker (A. Panganiban lab) 2001-2005: Karina Gallegos (A. Panganiban lab) 2003-2004: Vatsana Phaybouth (T. Barrett lab) 2004- 2008: Bradley Brown (A. Panganiban lab) 2004- 2008: Spencer Hansen (M. Lipscomb lab) 2004-2008: Jessica Smith (M. Ozbun lab) 2004-2007: Joann Maestas (M. Ozbun lab) 2005-2008: Darrell Dinwiddie (chair; K Harrod lab) 2008-2009: Xiaobo Sun (chair; K. Harrod lab) 2009-pres.: Jennifer Plourde (chair; K. Harrod lab) 2011- pres.: Mitchell Tyler (B. Chackerian lab) 2011: Abhishek Prasad (G. Ebel lab) 2011-pres.: Erin Crossey (B. Chackerian lab) External Graduate Thesis Committee Advisor 2000: Arlin Trocme, Univ. of Pittsburgh School of Public Hlth (MPH thesis review) 2001: William F. Pewen, Univ. of Pittsburgh SPH (MPH thesis review) Medical Students Research Projects 1997: Chris Poliage, MS II, Epidemiology of hantavirus in Peru 1998: Reetesh Pai, MS II, Hantavirus perinatal transmission risk factors (PIM Research Project) Honors in Research, 2000 Currently: Instructor in Cytopathology, Stanford University 1999: Bert Wofford, MS II, Deer mouse MHC II locus (PIM Research Project) Honors in Research, 2002 Currently: Family Practice Practitioner 2003: James Womack, MS II, Purification of rec. SN virus G1 antigen (PIM Research Project)

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2006: Felipe Terán (Universidad Desarrollo, Santiago Chile) Viral immunology 2006: Ruobing Xiao, MS II, Hantavirus Viral Load as Function of Severity of HCPS Illness. (PIM Research Project) 2008: Amar Patel, MSI, Detection of Hantavirus N Antigen in Blood of Patients with HCPS. (PIM Research Project) Medical Student Tutoring 1994- 1999: Tutor in Phase II, Infectious Diseases Block 1997-1999: Long term tutor, Infectious Diseases and Neoplasia Blocks 2000- 2002: Tutor in Neoplasia Block 2002-2003: Tutor in Mechanisms of Disease Block (year 1) 2005-2006: Tutor in Phase II, Infectious Diseases Block 2008-2009 Tutor in Phase II, Infectious Diseases Block 2010 Tutor in Immunology Block 2011 Tutor in Immunology Block Qualifying examination Committees for Biomed Sciences Ph.D. Students 1996, 1998, 1999 (Chair), 2000 (Chair) 2001 (Chair), 2002 (Chair) Mentorship Responsibilities: residents, faculty and fellows 1990-1991: Veronica Miller, Ph.D., Postdoctoral fellow Currently: Associate Res. Professor, Prevention and Comm. Health George Washington University 1990- 1991: Sarah Allen, M.D., Infectious Diseases Fellow, UNM, research mentor Currently: Associate Professor, Baylor Coll. of Medicine, Houston 1992: Carla Wilson, M.D., Ph.D., Resident in Pathology Currently: Full Professor, UNM School of Medicine 1993-1995: Takashi Yamada, M.D., Ph.D., Postdoctoral fellow Currently: Full Professor, OB/GYN, Hokkaido U. 1995-2000: Mausumi Bharadwaj, Ph.D., Postdoctoral fellow Currently: Assistant Director, Indian Council for Medical Research Chief, Div. of Molecular Genetics and Biochemistry Inst. Cytology and Preventive Oncology (ICMR), Noida, India 1995- 2000: Diane Goade, M.D., Assoc. Prof., UNM Department of Medicine (research mentor for Clinical Associate Physician Award, 1995-1997) Currently: Associate Prof, UNM Dept. of Medicine

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1996- 1997: Steven Simpson, M.D., Assistant Professor, UNM Department of Medicine (IDEA grant mentor) Currently: Associate Prof and Director, Pulmonary Fellowship University of Kansas School of Medicine DOIM 1999- 2003: Shu Yang, M.D., Ph.D., Infectious Diseases Fellow (co-mentor) Currently: Private practice, California 1999-2008: Wm. (Tony) Schountz, PhD, Mesa State College Currently: R15-funded Associate Prof of Microbiology, N Colorado Univ Promoted/tenured July 2008 1999-2002: Mary M. Ramos, M.D., Resident in Pediatrics Currently: Private practice, Albuquerque, NM 2000-2002: Jason Botten, Ph.D., Postdoctoral Fellow Currently: Assistant Professor, University of Vermont Internal Medicine 2001-2003: Keith Gottlieb, Ph.D., Postdoctoral Fellow Currently: Staff Scientist, Chromavision, San Juan Capistrano, CA 2001-2004: Barbara Masten, Ph.D., member, histocompatibility training progress committee Currently: Associate Professor of Pathology, UNM SOM 2001-2005: Alexander Dekonenko, Ph.D., Postdoctoral Fellow (Comentor with A. Panganiban 2001-2003) Currently: Staff Scientist, Dept Internal Medicine, UNM SOM 2001-2011: Adriana Kajon, Ph.D., Staff Scientist, Lovelace Respiratory Research Institute (Comentor with K. Harrod) Currently: Funded from NIH as PI, LRRI 2001-2003: US mentor for Rebeca Aldunate, Ph.D., Universidad Catolica de Chile, Santiago, Chile (P. Vial, Chilean mentor) Currently: Staff Scientist, U. Catolica de Chile 2003-2004: Member of postgraduate advisement committee Charlotte Vines, Ph.D. (E. Prossnitz lab) Currently: Assistant Professor, U Kansas, Kansas City 2004-2010: Fernando Torres-Perez, PhD, Postdoctoral fellow (Chile). Currently: Assistant Professor, Pontificia Universidad Catolica, Valparaiso, Chile (Comentor with J Cook, Department of Biology for Fogarty ABC fellow) 2006-2008: Pamela Hall, PhD (Comentor with R Larson, Dept of Pathology) Currently: Research Assistant Professor, UNM Dept MGM/ABQ VA Currently: PI Veterans Affairs Career Development Award 2006-2010 Tione Buranda, PhD Currently: Res Assistant Professor, Dept of Pathology 2006-2010: Mariana Acuna Retamar, DVM Currently: Profesor Instructor, Universidad de Chile, Santiago 2007-2009: Gregory Ebel, ScD., Assistant Professor

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Currently: Dr Ebel is an RO1-funded PI, Dept. of Microbiology, CSU 2007-2008: Rafael Medina-Flores, MD. Dr. Medina-Flores is a neuropathologist on the clinician-educator track Currently: Asst Professor, UNM School of Medicine 2008- 2009: Joseph Prescott, PhD Currently: Postdoctoral fellow Rocky Mountain Labs, NIAID 2009-2010 Candace Clay, PhD (K. Harrod lab) Member of postgraduate advisement committee 2009- 2011 Douglas Brackney, PhD (Greg Ebel lab) Member of postgraduate advisement committee Foreign and Outside Mentees 2005-2008: Tobias Manigold, MD Univ. Desarollo, Santiago de Chile I was a comentor for immunology projects with Dean Pablo Vial, UDD Currently: Lab-Head, Investigative Toxicology, Hoffman-La Rouche Visiting Scientists Oct 1997 Judy O’Brian, CHPPM-W, US Army, Aurora, CO (1 wk) Mar 1998 Maria Joao Alves PhD Instituto Nac’nal de Saude, Portugal (2 wk) May 1998 Matt Camaioni, grad student, Illinois State Univ, Normal (1 wk) Aug 1999 Hector Galeno, MS and Pablo Vial MD, Santiago, Chile (2 wk) Jan 2000 Nicolina Romano Lieber PhD, Univ de Sao Paulo, Brazil (1 mo) May 2000 Michele Jay and Leta Crawford-Miksza, Calif. DHS, VRDL, Berkeley Sep 2000 Rafael Medina, MS, Universidad Catolica, Santiago, Chile (6 wk) Oct 2000 Juan M. Pascale MD/PhD, Gorgas Mem. Institute, Panama (4 wk) Feb 2001 Maritza Navarrete, MD, U. Austral de Chile, Valdivia (3 wk) Feb 2001 Eliecer Villagra PhD, Inst. Salud Publica, Santiago, Chile (5 wk) Jun-Ag 2001 Hector Galeno, MS, Inst. Salud Publica, Santiago, Chile (9 wk) Apr- Sp 2002 Raul Cañate, MD, Gorgas Mem. Institute, Panama (with F. Koster) Jul 2002 Jorge Navarrete, Universidad Catolica, Santiago, Chile (2 wk) Dec 02-Jan 03 Hiroaki Kariwa MD/PhD, Hokkaido University, Sapporo Japan Mar 2003 Rebeca Aldunate PhD, Universidad Catolica, Santiago Chile Sep 2003 Marcela Ferres, MD, Universidad Catolica, Santiago, Chile (1 wk) Jul-Aug 2005 Mariana Acuña R, DVM, Facultad de Ciencias Veterinarias Pecuarias, Dept. Patología Animal, U Catolica, Santiago Chile (2 mo) Jun-Aug 2009 Felipe Alves Morais, Universidade de São Paulo, Instituto de

Biociências (GRA of Edison Luiz Durigon; 3 mo)

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Oct 2010- Jinlin Li, Wuhan University, China (1-year PhD exchange student) Oct 2011 Oct-Nov 2010 Maria Joao Yubero, MD, visiting scientist, Universidad Desarrollo,

Santiago, Chile (4-wk) Feb 2011 Cecilia Vial, PhD, visiting scientist, Universidad Desarrollo,

Santiago, Chile (2-wk) Mar-Apr 2011 Constanza Martinez, visiting scientist, Universidad Desarrollo,

Santiago Chile (1.5 mo) Trainees' Awards 1997 Mausumi Bharadwaj, PhD: Travel Award to ASTMH conference 1998 Jason Botten: Biomedical Science Graduate Achievement Award 1998 Jason Botten: Infectious Diseases and Inflammation Fellowship 1998 Diane Goade, M.D.: Young Investigator Award, UNM Department of Medicine 1999 Peggy Moran, Graduate Research Day Award (2nd place) 2000 Jason Botten: Travel Award to ASTMH conference, Houston TX 2002 Jason Botten, Ph.D., Keith Gottlieb, Ph.D., ASV Travel Award Recipients, Lexington, KY, 2002 2002 Jason Botten, Ph.D.: Joel M. Dalrymple Memorial Award, American Society of Virology, Lexington, KY 2002 Rafael Medina: American Society for Virology Travel Award 2003 Joseph Prescott: Departmental Citation for Research, Dept of Pathology, UNM School of Medicine 2004 Rafael Medina: Graduate Research Day Award (2nd place) UNM BSGP Travel Award to VI Intl Hantavirus Mtg, Seoul, Korea 2005 Rafael Medina: UNM BGSP Travel Award to XIII Intl Congress of Virology, San Francisco 2006 Felipe Terán, Tobi Manigold, Rafael Medina: “Best Scientific

Work” - see abstr #174 from abstract section, XXIII conference of the Chilean Society of Infectious Diseases

2006 Rafael Medina: UNM BSGP RTP Travel Award and UNM Grad/Prof Student SRAC Award for XIII Intl Conf on Negative Stranded RNA viruses, Salmanca, Spain 2007 Joseph Prescott: Travel award, 26th Ann Mtg Amer Soc Virol

Corvallis, 14-18 Jul Pamela Hall: Travel award, 26th Ann Mtg Amer Soc Virol

Corvallis, 14-18 Jul Rafael Medina: UNM Grad & Prof Student Association (GPSA) Graduate Research and Development (GRD) Award to fund

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Dissertation project, “Sin Nombre hantavirus-host interactions: in vivo inhibition and viral entry in the deer mouse model”.

2008 Pamela Hall, PhD, Postdoctoral Fellow 1 F32 AI074246-01A1 "Characterization of innate immune response stimulation by SNV" 4/10/08-4/09/09 2008 Ruobing Xiao, MD, Med Student Trainee William Scott Hayes Outstanding Medical Research Award For work done as medical student in Hjelle Laboratory CLINICAL DUTIES: 1989-1997 Plasmapheresis service, Blood Systems Inc. 1989- 1997 Associate Medical Director, Blood Systems, Inc. 1993- pres Developed and implemented hantavirus diagnostic tests 1997- pres Direct production and QC of hantavirus antibody test for TriCore Corp. 1993- pres Primary interpreter of hantavirus antibody tests Dec 97- pres: Associate Director, Molecular Diagnostics Core Laboratory University of New Mexico Hospital/TriCore Corp. Dec 97- pres: Manufacture/QC of hantavirus diagnostic test for TriCore UNIVERSITY OF NEW MEXICO: COMMITTEES AND OTHER ADMINISTRATIVE SERVICES Department of Pathology: Interim Chair, 2006- 2008 Vice-Chair for Research, 2002-2009 Pathology Department Research Committee, 1995 -2009 Chair, 2002- 2009 Pathology Informatics/Computer Committee, 1998- 2005 Pathology Education Committee, 1998-2007 RFP Review Committee in Experimental Pathology, 1996-2008 Pathology Staff Award Committee, 1998-2001, 2004-2006 Pathology Steering Committee, 2002-2008 Pathology Endowment Committee, 2002-2008 Pathology Resident-Fellows Foucar-Foundation Awards Reviews 2005-2008 Pathology FIBCI (merit pay) Committee 2005 School of Medicine and Health Sciences Center

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Faculty Co-director of Biosafety Level 3 Facility 1990-2003 Chair, Biosafety Level 3 Users' Committee 1990-2006 Cellular and Molecular Basis for Disease Seminar Committee 1995-1998; 1999-2001 Search Committee, Virologist, UNM Cell Biology Dept., 1993 UNM Office of Medical Investigator Unexplained Deaths Committee 1995-1997 Howard Hughes Medical Institution Steering Committee 1996-1999 School of Medicine Dean’s Scientific Advisory 1996-1999; 2002- 2006 Space Subcommittee, 2002 Search Committee, UNM-HHMI Molecular Epidemiologist, 1997-8; 1998-9 DNA Sequencer Users’ Committee, 1997-2000 Biomedical Graduate Student Steering Committee, 1998- 2004 Subcommittee on recruitment May 2000- 2004 RFA Evaluation Committee, Infectious Diseases and Inflammation Training Grant, 2000 (Chair) Liaison Committee for Medical Education 2001-2003 Subcommittee on graduate education 2001- 2003 School of Medicine Space Committee, 2003-2008 School of Medicine Research Executive Council 2002-5 Human Tissue Oversight Committee (HTOC) 2003-2008 Search Committee, Chair of Pathology, 2005-2006 School of Medicine Research Science Planning Committee (RSCP) 2006-2008 School of Medicine Committee of Chairs 2006-2008 School of Medicine Committee of Basic Sciences Chairs 2006-2008 Search Committee Chair, Dept Pathology Virologist 2009-2010 University of New Mexico UNM Institutional Biosafety Committee 1993-2005 rDNA application review subcommittee 1998-2005 Search Committee for Biosafety Officer 2001-2002 Director, Center for Emerging Infectious Diseases 2001-2002 Committee on Undergraduate Research 2003-2006 Institutional Animal Care and Use Committee 2005- 2006 Board of Directors, UNM Medical Group (Faculty Practice Org UNMMG) 2006-8 Clinical and Translational Sciences Award Committees, UNM CTSC Career Development Committee 2006 CTSC MAC (Multidisciplinary Advisory Council) 2007-2011 Chair 2008-2011

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CTSC Research Core Leadership Group 2007-2008 CTSC Masters in Clinical Research Curriculum Committee 2006-7 CTSC Educational Core 2007 CTSC Novel Technologies Committee 2007-2009

PROFESSIONAL AND SCIENTIFIC ORGANIZATIONS: American Association for the Advancement of Science (1979- present) American Committee on Arthropod-borne Viruses ACAV Subcommittee on Interrelationships among Catalogued Arboviruses and other viruses (SIRACA) American Society for Investigative Pathology ASIP Association of Pathology Chairs APC Infectious Diseases Society of New Mexico College of American Pathologists CAP Member, Collaborative Antiviral Study Group (NIAID), 1993-2001 International Association of Retroviruses (charter member) American Society of Tropical Medicine and Hygiene American Society for Virology New Mexico representative, National Leukemia Association Inc. 1991- present Local Organizing Committee, International Society for Antiviral Research, annual meeting April 23-28, 1995, Santa Fe, NM Chair, Bunyavirus workshop, American Society for Virology meeting, London, Ontario July 13-17, 1996 Co-Chair, Hantavirus workshop, American Society for Tropical Medicine and Hygiene 44th Annual Meeting, Baltimore, December 1-5, 1996 Co-Chair, Genetics plenary session, Fourth International Conference on HFRS And Hantaviruses, Atlanta, March 5-7, 1998 Co-Chair, Hantavirus and arenavirus workshop, American Soc for Trop Med Hyg 48th annual meeting, Washington DC Nov 27-Dec 2, 1999 Co-Chair, immunology workshop, Keystone Symposium on Genetics Pathogenesis and Ecology of Emerging Viral Diseases, Taos, NM, Jan 24-30, 2000 Science Committee member (alternate) New Mexico Bioresearch Consortium (UNM/Sandia National Labs/ New Mexico Department of Health/NMSU) 2002- 2005 Co-Chair, Viruses II, American Soc for Tropical Med Hyg 55th annual meeting, Atlanta, Nov 12-16, 2006 United States and Canadian Association of Pathologists USCAP Board of Directors, TriCore Reference Laboratories (2007-2008) Quality Committee, TriCore Reference Laboratories (2008)

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JOURNAL RESPONSIBILITIES: Ad Hoc Reviewer: American J of Tropical Medicine and Hygiene (reg. Reviewer, 1998) American Journal of Medicine Annals of Internal Medicine (registered reviewer, Jan 1993-present) Clinical and Diagnostic Immunology

Clinical and Diagnostic Laboratory Immunology Emerging Infectious Diseases European Journal of Epidemiology International Journal of Cancer Journal of Acquired Immunodeficiency Syndrome and Human Retrovirology Journal of Biomedical Sciences Journal of Clinical Microbiology Journal of General Virology Journal of Infectious Diseases Journal of Virological Methods Journal of Virology Molecular and Cellular Biology

Science Transfusion Veterinary Pathology Virology Virus Research Vox Sanguinis Western Journal of Medicine Editorial Board member: Virus Genes (2006- present) Journal of Inflammation Research (2008-present) Viruses (Open Access) Editor, Pathogenesis of Emerging RNA Viruses (2010-11) GRANT REVIEW ACTIVITIES: 1994 Ad hoc grant reviewer, National Heart, Lung, and Blood Institute (study section) 1995 External ad hoc grant reviewer, NIH, National Center for Research Resources

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1995 External ad hoc grant reviewer, Natural Sciences and Engineering Research Council (Canada) 1996 External ad hoc grant reviewer, National Science Foundation 1997 External ad hoc grant reviewer, Fogarty Foundation, NIH External ad hoc grant reviewer, VA Merit Award 1998- 1999 American Cancer Society IRG, UNM School of Medicine 1999-2001 External grant reviewer, Medical Infectious Diseases Research Program (MIDRP), administered by American Inst. for Biological Sciences (AIBS) 2000- present External ad hoc grant reviewer, Civilian Research and Development Foundation (CRDF) 2003 External ad hoc grant reviewer, VA Merit Award Ad hoc grant reviewer, NIAID (two study sections) Ad Hoc Member, Tropical Medicine and Parasitology Study Section, NIAID External reviewer, Joint Military Infectious Diseases Conference (Programmatic review of military infectious diseases priorities) 2005 IDM (12) Viral and Eukaryotic Pathogens Special Emphasis Panel

Study Section

2006 Biotechnology Engagement Program BTEP reviewer for International Science and Technology Center (ISTC) 2009 NIAID Reviewer- Challenge/ARRA grant applications 2010 NCRR Reviewer – Clinical and Translational Research Awards (CTSA) 2011 NIAID Reviewer, Preclinical Services for Development of Biopharmaceutical Products for Infectious Diseases 2011 NIAID Reviewer, Acceleration of Immune Response to Biodefense Pathogens 2012 NIAID Reviewer, Special Emphasis Panel Virology

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INVITED LECTURES AND PROFESSORSHIPS (SELECTED): Jan 14, 1994: Visiting Professor, University of California, Berkeley Feb 9, 1994: Western Association of Physicians Distinguished Lecturer Award, Carmel, CA Aug 26, 1994: Visiting Scientist, California Department of Health, Viral and Rickettsial Diseases Laboratory, Berkeley Oct 3, 1994: Plenary Speaker, Society for Vector Ecology, Gainesville, FL Jan 31, 1995: Visiting Scientist, New York State Department of Health, Albany May 25, 1995: Visiting Professor, Fred Hutchinson Cancer Research Center, Seattle Mar 1, 1996: Visiting Professor, Yale University Dept. of Epidemiology and Public Health, New Haven, CT Apr 2, 1996: Visiting Professor, Scripps Research Institute, La Jolla, CA Nov, 1996: Visiting Professor, Universidad de Buenos Aires Escuela de Medicina, Argentina Jan 8, 1997: New Mexico State University Zuni Symposium, plenary, Las Cruces, NM Sep 14-24, 1997: Visiting Professor, Paraguayan Ministry of Health, Asuncion Dec 16, 1997: Visiting Professor, Clinica Alemana, Santiago de Chile Feb 17, 1998: Visiting Professor, Bolivian Ministry of Health, La Paz Apr 6, 1998: Visiting Professor, Texas Tech University, Lubbock, TX Oct 28, 1998: Lecturer, Fondation Marcel Mérieux Conference on Emergence and Control of Rodent-Borne Diseases, Annecy, France Nov 3, 1998: Visiting Professor, Hospital de S. Bernardo, Setúbal, Portugal Mar 22, 1999: Visiting Professor, Charité Medical School, Humboldt University Berlin

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May 5-6, 1999: Visiting Professor, University of Texas, Austin Jan 27, 2000: Speaker (substitute), Keystone Symposium on Genetics, Pathogenesis, and Ecology of Emerging Viral Diseases, Taos, NM Jan 28, 2000: Speaker (substitute), Keystone Symposium on Pathogen Discovery: from Molecular Biology to Diseases, Taos, NM Mar 6, 2000: Plenary speaker, Hantavirus Ecology and Disease Conference, Temuco, Chile Mar 7, 2000: Workshop rapporteur, Virology Laboratory, Hantavirus Ecology and Disease Conference, Temuco, Chile Oct 5, 2000: Visiting Professor, New Mexico State University, Dept of Chemistry and Biochemistry, Las Cruces, NM Oct 14, 2000: Plenary Speaker, American Society for Microbiology Rocky Mountain Branch, Grand Junction CO Oct 24, 2000: Visiting Professor, Los Alamos National Laboratory, Biosciences Division, Los Alamos, NM Nov 14-15, 2000: Visiting Professor, Scripps Research Institute, La Jolla, CA Nov 24, 2000: Visiting Professor, Los Alamos National Laboratory, NM Nov 30, 2000: Visiting Professor, Humboldt State University, Arcata, CA Apr 25, 2001: Visiting Professor, University of Manitoba, Medical Microbiology Department, Winnipeg, MB Apr 26, 2001: Visiting Professor, Health Canada, National Microbiology Laboratory, Winnipeg, MB Sep 25-28, 2001: Speaker, 3rd Intl Conference on Virus-Like Particles, Berlin Oct 11-12, 2001: Plenary Speaker, 1st Scientific Meeting for Emerging Infections (Hantavirus), Instituto Conmemorativo Gorgas, Panama City Apr 2-4, 2002: Speaker, Third Annual Meeting for Hantavirus Epidemiology and

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Disease, Puerto Varas, Chile Dec 5-6, 2002: Speaker, Emerging Infectious Diseases and Bioterrorism: Regional Threats Global Impact, University of California, Davis, CA Apr 13-14, 2003: Visiting Professor, University of Rochester School of Medicine Department of Microbiology and Immunology Aug 5, 2003: Plenary Speaker, Int’l Conference on Diseases of Nature Communicable to Man, Northern Arizona University, Flagstaff Aug 26-27, 2003: Visiting Professor, Universidade de Sao Paolo, Ribeirão Preto Faculdade de Medicina, Brazil Aug 29, 2003: Invited speaker, Federação de Sociedades de Biologia Experimental (FeSBE), Curitiba, Paraná, Brazil Sep 3-4, 2003: Visiting Professor, Universidade Federal de Rio de Janeiro, Faculdade de Medicina, Brazil Sep 15, 2003: Co-convener and speaker, 43rd Interscience Conference on Antimicrobial Agents & Chemotherapeutics (ICAAC), Symposium 140, Chicago Nov 7, 2003: Visiting Scholar, Institute for Virology, Chinese CDC, Beijing Nov 10, 2003: WHO Consultant, Program Reviewer for Hemorrhagic Fever with Renal Syndrome and Visiting Scholar, Hebei Centers for Disease Control, Shijiazhuang, Hebei, China Nov 12, 2003: WHO Consultant, Program Reviewer for Hemorrhagic Fever with Renal Syndrome and Visiting Scholar, Shandong Centers for Disease Control, Jinan, Shandong, China Feb 24, 2004: Visiting Professor, Southwest Foundation San Antonio, Texas Dec 3, 2004: Speaker, III Symposium on Arbovirology, Belem, PA Brazil Nov 12, 2005: Visiting lecturer, Univ of Utah Biodefense EID series, Salt Lake City,

Utah Mar 6, 2006: Visiting lecturer, Universidade Federale Rio de Janeiro Brazil

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Mar 7, 2006: Visiting lecturer, FIOCRUZ Institute Rio de Janeiro Brazil Dec 5, 2006: Visiting lecturer, N Carolina Biotechnology Center, Raleigh Mar 30, 2007: Visiting lecturer, Hantavirus Ecology and Disease in Chile VI Intl Mtg Concepción, Chile May 30, 2008: Speaker, Banff Conference on Infectious Diseases, Alberta, Canada Jun 24, 2009: Visiting lecturer, Rocky Mtn Lab (NIAID), Hamilton, MT Nov 19, 2009: Co-led Symposium at American Society for Tropical Medicine and Hygiene, Washington, DC Sep 30, 2011: Grand Rounds speaker, St. Charles Healthcare Syst, Bend, OR Dec 9, 2011: Center for Infection and Immunity Distinguished Lecture Series Columbia Univ. Mailman School of Public Health, New York, NY COUNTER-BIOTERRORISM ACTIVITIES (SELECTED) Apr 7, 1999: Participant, conference with aerosol and infectious diseases bioweapons experts from Russia. Lovelace Respiratory Research Institution, Albuquerque, NM. Apr 16, 1999: Co-hosted visit by infectious diseases/bioweapon and pharmaceutical scientists from Vector Laboratories, Novosibirsk, Siberia, Russia. UNM SOM, Albuquerque, NM. Jun 2-3, 1999: Speaker and participant, “Emerging Technologies vs. Emerging Threats: Focus on Weapons of Mass Destruction and Homeland Defense" symposium, Sandia National Laboratories, Albuquerque, NM. Jun 27-Jul 2, 1999: Co-host, visiting bioweapons scientists from Kazakhstan. Sponsored by US State Department. UNM School of Medicine and related institutions, Albuquerque, NM. Aug 27, 1999: Participant, Biological Defense Consortium, Santa Fe Sep 22-23, 1999: Speaker and participant, “WMD Emergency Responders Symposium”

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Honolulu Oct 27, 1999: Speaker and participant, Biological Defense Consortium, Santa Fe Mar 16-17, 2001: Discussion Group member, Unified Science and Technology for Biological Threat Reduction meeting, Albuquerque, NM Mar 14-15, 2002: Presenter, Second Annual Unified Science and Technology for Biological Threat Reduction meeting, Albuquerque, NM Jul 2000- Dec 2002: Assisting designers and architects with planning Quadlab Service/Research Building for State Laboratory, Medical Investigator, Veterinary Diagnosis, and UNM Center for Emerging Infectious Diseases Jun 13-15, 2006: Speaker and Discussant, Defense Threat Reduction Agency (DTRA) Symposium on Counter-Bioweapon Technologies, Ft. Belvoir, VA GRANT SUPPORT-FUNDING (CURRENT) Jun 1999- Aug 2015 National Institute of Allergy and Infectious Diseases U01 AI45452 "Hantavirus Ecology and Disease in Chile" (ICIDR) Role: Coinvestigator $500,000 direct PI: G. Mertz (Hjelle 10 % salary) Dec 2010 – Nov 2012 National Institute for Allergy and Infectious Diseases RO3 AI092130 “Spatiotemporal Regulation of Membrane Raft Trafficking in Virus Activated Cells” Role: Coinvestigator $50,000 direct PI: T Buranda (Hjelle 1% salary) Sep 2010- Aug 2012 National Institute for Allergy and Infectious Diseases R21 NS066429 “Development of HTS Assays for Inhibitors of Viral-Cell Interactions” Role: Coinvestigator $100,000 direct PI:T Buranda (Hjelle 5% salary) PATENTS: 8/26/1993: " Hantavirus-Associated Respiratory Distress Virus Antigens"

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awarded by USPTO 17 November 1998 (No. 5,837,441). MC-087. "Molecular Clones Producing Recombinant DNA Antigens of the HARDS Virus" awarded by USPTO 13 November 2001 (No. 6,316,250 B1). 6/27/1996: “Rio Mamoré Hantavirus Nucleocapsid Proteins and Diagnostic Methods Employing Said Protein”, awarded by USPTO 9 July 2002 (No. 6,416,761 B1). 9/14/2001: “Heat Shock Response and Virus Replication” Submitted, USPTO (coinventor with P. Moseley, A. Panganiban, and M. Ozbun). 7/9/2004: “A Cellular-Based Method for Detecting Viruses and Reagents Therefor”. Provisional submitted 9 Jul 2004, USPTO no. 60/546,949. MC -229. 7/8/2005: “A Cellular-Based Method for Detecting Viruses and Reagents Therefor”. Submitted 8 Jul 2005. MC –229 appl no 60/586,949. 2/2/2007: “Peptides that Bind and Inhibit Sin Nombre Virus” (MC-366). Disclosed 2 Feb 2007. 2/9/2007: “Ligand-Based Biosensor for Detection of Microbes” (MC-365). Provisional patent application 60/900,416; filed 9 Feb 2007. 2/2012 “VLPs for discovery of broadly neutralizing and diagnostic epitopes of immunogens, infectious agents or allergens of humans and animals” (In progress of submission) ORIGINAL PEER-REVIEWED PUBLICATIONS: 1. Phillips JA III, Hjelle BL, Seeburg PH, Zachmann M. Molecular basis for familial isolated growth hormone deficiency. Proc Natl Acad Sci USA 1981; 78: 6372-75. (Cited 194 times by Aug 08) 2. Hjelle BL, Phillips JA III, Seeburg PH. Relative levels of methylation in human growth hormone and chorionic somatomammotropin genes in expressing and non-expressing tissues. Nucl Acids Res 1982; 10: 3459-74.

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3. Phillips JA III, Parks JS, Hjelle BL, Herd JE, Plotnick L, Migeon CJ, Seeburg PH. Genetic analysis of familial isolated growth hormone deficiency type I. J Clin Invest 1982; 70: 489-95. 4. Pardoll DM, Charache S, Hjelle BL, Jones R, Phillips JA III, Smith RRL, Rodeheffer R. Homozygous alpha thalassemia/Hb G Philadelphia. Hemoglobin 1982; 6: 503-15. 5. Hjelle B, Charache S, Phillips JA III. Hemoglobin H disease and multiple congenital anomalies in a child of northern European origin. Am J Hematology 1982; 13: 319-22. 6. Rivarola MA, Phillips JA III, Migeon CJ, Heinrich JJ, Hjelle BL. Phenotypic heterogeneity in familial isolated growth hormone deficiency (IGHD) type A. J Clin Endocrinol Metab 1984; 59: 34-40. 7. Liu ET, Hjelle B, Morgan R, Hecht F, Bishop JM. Mutations of the Kirsten-ras proto-oncogene in human preleukaemia. Nature 1987; 330: 186-88. 8. Liu E, Hjelle B, Bishop JM. Transforming genes in chronic myelogenous leukemia. Proc Natl Acad Sci USA 1988; 85: 1952-56. 9. Hjelle B, Liu E, Bishop JM. Oncogene v-src transforms and establishes embryonic rodent fibroblasts but not diploid human fibroblasts. Proc Natl Acad Sci USA 1988; 85:4355-9. 10. Hjelle B, Donegan E, Cruz J, Stites D. Antibody to c antigen consequent to renal transplantation. Transfusion 1988; 28: 496-98. 11. Hjelle B, Evans-Holm M, Yen T-SB, Garovoy M, Guis M, Edman JC. Poorly-differentiated lymphoma of donor origin in a renal allograft recipient. Transplantation 1989; 47: 945-48. (Cited 47 times by Jan 09) 12. Kurtz TW, Simonet L, Kabra P, Wolfe S, Chan L, Hjelle B. A renin allele of the spontaneously hypertensive rat cosegregates with increased blood pressure. J Clin Invest 1990; 85: 1328-32. (Cited 174 times by Aug 08) 13. Hjelle B, Mills R, Mertz G, Swenson S. Transmission of HTLV-II via blood transfusion. Vox Sanguinis 1990; 59: 119-22. (Cited 37 times by Jan 04) 14. Hjelle B, Scalf R, Swenson S. High frequency of human T-cell leukemia-lymphoma virus type II infection in New Mexico blood donors: Determination by sequence-specific oligonucleotide hybridization. Blood 1990; 76: 450-4. (Cited 94 times by Aug 08)

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15. Hjelle B, Mills R, Swenson S, Mertz G, Key C, Allen S. Incidence of hairy cell leukemia, mycosis fungoides, and chronic lymphocytic leukemia in first known HTLV-II-endemic population. J Infect Dis 1991; 163: 435-40. (Cited 89 times by Aug 08) 16. Hjelle B, Cyrus S, Swenson S, Mills R. Serologic distinction between human T-lymphotropic virus (HTLV) type I and HTLV type II.Transfusion 1991; 31: 731-6. 17. Hjelle B, Chaney R. Sequence variation of functional HTLV-II tax alleles among isolates from an endemic population: Lack of evidence for oncogenic determinant in tax. J Med Virol 1992; 36: 136-41. 18. Davis LE, Hjelle BL, Miller VE, Palmer DL, Llewellyn AL, Merlin TL, Young SA, Mills RG, Wachsman W, Wiley CA. Early viral brain invasion in iatrogenic human immunodeficiency virus infection. Neurology 1992; 42: 1736-9. (Cited 230 times by Aug 08) 19. Lal RB, Rudolph DL, Kaplan JE, Hjelle B, Levine PH, Coligan JE, Viscidi RP. Identification of immunodominant epitopes in external glycoprotein of human T lymphotropic virus-type II. Virology 1992; 186: 274-9. 20. Hjelle B, Appenzeller O, Mills R, Alexander S, Torrez-Martinez N, Jahnke R, Ross G. Chronic neurodegenerative disease associated with HTLV-II infection. Lancet 1992; 339: 645-6 (Cited 172 times by Feb 2006). 21. Hjelle B, Mills R, Goldsmith C, Swenson SG, Cyrus S. Primary isolation of HTLV-I and HTLV-II: use in confirming infection in sero-indeterminate blood donors. J Clin Micro 1992; 30: 2195-9. 22. Buckner C, Roberts CR, Foung SKH, Lipka J, Reyes GR, Hadlock K, Chan L, Gongora-Bianchi RA, Hjelle B, Lal RB. Immune responsiveness to the immunodominant envelope epitopes of HTLV-I and HTLV-II in diverse geographic populations. J Infect Dis 1992; 166: 1160-3. 23. Lal RB, Hjelle B, Rudolph DL. Spontaneous proliferation of HTLV-II-infected peripheral blood lymphocytes: HLA-DR-driven, IL-2-dependent response. Microbiol Immunol 1992; 36: 865-72. 24. Hjelle B, Wilson C, Cyrus S, Bradshaw P, Lo J, Schammel C, Wiltbank T, Alexander S. Human T-cell leukemia virus type II infection frequently goes undetected in contemporary U.S. blood donors. Blood 1993; 81: 1641-4. (Cited 41 times by Dec 2005)

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25. Harrington WJ Jr, Sheremata W, Hjelle B, Dube D, Bradshaw P, Foung S, Toedter G, Cabral L, Poiesz B. Spastic ataxia associated with HTLV-II infection. Ann Neurol 1993; 33: 411-4. (Cited 86 times by July 08) 26. Hjelle B, Zhu SW, Takahashi T, Ijichi S, Hall WW. Endemic HTLV-II infection in southwestern U.S. Indians involves two prototype variants of virus. J Infect Dis 1993; 168: 737-40. (Cited 61 times by Dec 2007) 27. Hjelle B, Jenison S, Torrez-Martinez N, Damrow TA, and Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention. Progress in development of hantavirus diagnostic assays - United States. Morb Mortal Weekly Report 1993; 42: 770-2. 28. Hjelle B, Khabbaz RF, Conway GA, North C, Green D, Kaplan JE. Prevalence of HTLV-II in HTLV-II-endemic populations of the southwestern United States. Am J Trop Med Hyg 1994; 51: 11-5. 29. Hjelle B, Jenison S, Torrez-Martinez N, Yamada T, Nolte K, Zumwalt R, MacInnes K, Myers G. A novel hantavirus associated with an outbreak of fatal respiratory disease in the southwestern United States: evolutionary relationships to known hantaviruses. J Virol 1994; 68: 592-6. (Cited 109 times by July 08) 30. Foucar K, Nolte KB, Fedderson RM, Hjelle B, Jenison S, McLaughlin J, Madar DA, Young SA, Zaki SR, Hughes L, McFeeley PJ, Simpson GL, Koster FT. Outbreak of hantavirus pulmonary syndrome in the southwestern United States: response of pathologists and other laboratorians. Am J Clin Pathol 1994; 101: S1-S5. 31. Palmer DL, Hjelle BL, Wiley CA, Allen S, Wachsman W, Mills RG, Davis LE, Merlin TL. Primary HIV infection despite combination antiviral therapy after infusion of contaminated white cells. Am J Med 1994; 97: 289-295. 32. Jenison S, Yamada T, Morris C, Anderson B, Torrez-Martinez N, Keller N, Hjelle B. Characterization of human antibody responses to Four Corners hantavirus infections among patients with hantavirus pulmonary syndrome. J Virol 1994; 68: 3000-6. (Cited 115 times by July 08) 33. Hjelle B, Jenison S, Mertz G, Koster F, Foucar K. Emergence of hantaviral disease in the southwestern United States. Western J Med 1994; 161: 467-73. 34. Hjelle B, Spiropoulou CF, Torrez-Martinez N, Morzunov S, Peters CJ, Nichol ST. Detection of Muerto Canyon virus RNA in peripheral blood mononuclear cells from patients with hantavirus pulmonary syndrome. J Infect Dis 1994;170:1013-7. (Cited 47 times by Jan 08)

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35. Hjelle B, Chavez-Giles F, Torrez-Martinez N, Yamada T, Sarisky J, Ascher M, Jenison S. Dominant glycoprotein epitope of Four Corners hantavirus is conserved across a wide geographical area. J Gen Virol 1994; 75: 2881-8. (Cited 32 times by July 08) 36. Nerurkar VR, Song K-J, Song J-W, Nagle JW, Hjelle B, Jenison S, Yanagihara R. Genetic evidence for a hantavirus enzootic in deer mice (Peromyscus maniculatus) a decade before the recognition of hantavirus pulmonary syndrome. Virology 1994; 204: 563-8. 37. Hjelle B, Chavez-Giles F, Torrez-Martinez N, Yates T, Sarisky J, Webb J, Ascher M. Genetic identification of a novel hantavirus of the harvest mouse Reithrodontomys megalotis. J Virol 1994; 68: 6751-4. (Cited 78 times by July 08) 38. Hjelle B, Krolikowski J, Torrez-Martinez N, Chavez-Giles F, Vanner C, Laposata E. Phylogenetically distinct hantavirus implicated in a case of hantavirus pulmonary syndrome in the northeastern United States. J Med Virol 1995; 46: 21-7. (Cited 35 times by July 08) 39. Yamada T, Hjelle B, Lanzi R, Morris C, Anderson B, Jenison S. Antibody responses to Four Corners hantavirus in the deer mouse (Peromyscus maniculatus): identification of an immunodominant region of the nucleocapsid protein. J Virol 1995; 69: 1939-43. 40. Hjelle B, Anderson B, Torrez-Martinez N, Song W, Gannon WF, Yates TL. Prevalence and geographic genetic variation of hantaviruses of New World harvest mice (Reithrodontomys): identification of a divergent genotype from a Costa Rican Reithrodontomys mexicanus. Virology 1995; 207: 452-9. (Cited 47 times by July 08) 41. Pardi D, Hjelle B, Folks TM, Lal RB. Genotypic characteristics of HTLV-II isolates from Amerindian and non-Indian populations. Virus Genes 1995;10: 27-35. 42. Eiraku N, Monken C, Kubo T, Zhu SW, Rios M, Bianco C, Hjelle B, Nagashima K, Hall WW. Nucleotide-sequence and restriction-fragment-length-polymorphism analysis of the long terminal repeat of human T cell leukemia-virus type-II. AIDS Res Human Retroviruses 1995; 11: 625-36. 43. Hjelle B, Lee S-W, Song W, Torrez-Martinez N, Song J-W, Yanagihara R, Gavrilovskaya I, Mackow ER. Molecular linkage of hantavirus pulmonary syndrome to the white-footed mouse, Peromyscus leucopus: genetic characterization of the M genome of New York virus. J Virol 1995; 69: 8137-41. (Cited 58 times by July 08)

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44. Torrez-Martinez N, Song W, Hjelle B. Nucleotide sequence analysis of the M genomic segment of El Moro Canyon hantavirus: antigenic distinction from Four Corners hantavirus. Virology 1995; 211: 336-8. 45. Song W, Torrez-Martinez N, Irwin W, Harrison J, Davis R, Ascher M, Jay M, Hjelle B. Isla Vista virus: a genetically novel hantavirus of the California vole Microtus californicus. J Gen Virol 1995; 76: 3195-9. (Cited 31 times by July 08) 46. Chu Y-K, Jennings G, Schmaljohn A, Elgh F, Hjelle B, Lee H-W, Jenison S, Ksiazek T, Peters CJ, Rollin P, Schmaljohn CS. Cross-neutralization of hantaviruses with immune sera from experimentally-infected animals and from HFRS or HPS patients. J Infect Dis 1995; 172: 1581-4. 47. Jay M, Hjelle B, Davis R, Ascher M, Baylies HN, Reilly K, Vugia D. Occupational exposure leading to hantavirus pulmonary syndrome in a utility company employee. Clin Infect Dis 1996; 22: 841-4. 48. White DJ, Means RG, Birkhead GS, Bosler EM, Grady LJ, Chatterjee N, Woodall J, Hjelle B, Rollin PE, Ksiazek TG, Morse DL. Human and rodent hantavirus exposure in New York State; public health significance of an emerging infectious disease. Arch Int Med 1996; 156: 722-6. 49. Song J-W, Baek LJ, Gavrilovskaya IN, Mackow ER, Hjelle B, Yanagihara R. Sequence analysis of the complete S genomic segment of a newly identified hantavirus isolated from the white-footed mouse (Peromyscus leucopus): phylogenetic relationship with other sigmodontine rodent-borne hantaviruses. Virus Genes 1996; 12: 249-58. 50. Semmes OJ, Majone F, Cantemir C, Turchetto L, Hjelle B, Jeang K-T. HTLV-I and HTLV-II tax: differences in induction of micronuclei in cells and transcriptional activation of viral LTRs. Virology 1996; 217: 373-9. 51. Hjelle B, Torrez-Martinez N, Koster FT, Jay M, Ascher MS, Brown T, Reynolds P, Ettestad P, Voorhees RE, Sarisky J, Enscore RE, Sands L, Mosley D, Kioski C, Bryan RT, Sewell CM. Epidemiologic linkage of rodent and human hantavirus genomic sequences in case investigations of hantavirus pulmonary syndrome. J Infect Dis 1996; 173: 781-6. 52. Biggar RJ, Taylor ME, Neel JV, Hjelle B, Levine PH, Black FL, Sharp PM, Shaw GM, Hahn BH. Genetic variants of human T-lymphotropic virus type II in American Indian groups. Virology 1996; 216: 165-73.

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53. Hjelle B, Goade D, Torrez-Martinez N, Lang-Williams M, Kim J, Harris RL, Rawlings JA. Hantavirus pulmonary syndrome, renal insufficiency and myositis associated with infection by Bayou hantavirus. Clin Infect Dis 1996; 23: 495-500. (Cited 35 times by July 08) 54. Rawlings JA, Torrez-Martinez N, Neill SU, Moore GM, Hicks BN, Pichuantes S, Nguyen A, Bharadwaj M, Hjelle B. Cocirculation of multiple hantaviruses in Texas, with characterization of the S genome of a previously-undescribed virus of cotton rats (Sigmodon hispidus). Am J Trop Med Hyg 1996; 55: 672-679. (Cited 30 times by July 08) 55. Elgh F, Lundkvist Å, Alexeyev OA, Stenlund H, Avsic-Zupanc T, Hjelle B, Lee HW, Smith KJ, Vainionpaa R, Wiger D, Wadell G, Juto P. Serological diagnosis of hantavirus infections by an enzyme-linked immunosorbent assay based on detection of immunoglobulin G and M responses to recombinant nucleocapsid proteins of five viral serotypes. J Clin Microbiol 1997; 35: 1122-30. 56. Hjelle B, Jenison S, Torrez-Martinez N, Herring B, Quan S, Polito A, Pichuantes S, Yamada T, Morris C, Elgh F, Lee HW, Artsob H, DiNello R. Rapid and specific detection of Sin Nombre virus antibodies in patients with hantavirus pulmonary syndrome by a strip immunoblot assay suitable for field diagnosis. J Clin Microbiol 1997; 35: 600-8. 57. Jay M, Ascher MS, Chomel BB, Madon M, Sesline D, Enge B, Hjelle B, Ksiazek TG, Rollin PE, Kass PH, Reilly K. Sero-epidemiological studies of hantavirus infection among wild rodents in California Emerg Infect Dis 1997; 3: 183-190. http://www.cdc.gov/ncidod/ eid/vol3no2/jay.htm 58. Bharadwaj M, Botten J, Torrez-Martinez N, Hjelle B. Rio Mamoré virus: genetic characteristics of a newly-recognized hantavirus of the pygmy rice rat Oligoryzomys microtis from Bolivia. Am J Trop Med Hyg 1997; 57: 368-74. (Cited 43 times by July 08) 59. Torrez-Martinez N, Bharadwaj M, Goade D, Delury J, Moran P, Hicks B, Nix B, Davis J, Hjelle B. Bayou virus-associated hantavirus pulmonary syndrome in eastern Texas: identification of Oryzomys palustris as the reservoir host. Emerg Infect Dis 1998; 4: 105-11. http://www.cdc.gov/ncidod/eid/vol4no1/torrez.htm 60. Malecki TM, Jillson GP, Thilsted JP, Elrod J, Torrez-Martinez N, Hjelle B. Serologic survey for hantavirus infection in domestic animals and coyotes from New Mexico and northeastern Arizona. J Am Vet Med Assoc 1998; 212: 970-973. 61. Green W, Feddersen R, Yousef O, Behr M, Smith K, Nestler J, Jenison S, Yamada T, Hjelle B. Tissue distribution of hantavirus antigen in naturally infected humans and deer mice. J Infect Dis 1998; 177: 1696-1700.

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62. Ferrer JF, Jonsson C, Esteban E, Galligan D, Basombrio MA, Peralta-Ramos M, Bharadwaj M, Torrez-Martinez N, Segovia A, Hjelle B. High prevalence of hantavirus antibodies in Indian communities of the Paraguayan and Argentinean Gran Chaco. Am J Trop Med Hyg 1998; 59: 438-44. 63. Bennett SG, Webb JP Jr. Madon MB, Childs JE, Ksiazek TG, Torrez-Martinez N, Hjelle B. Hantavirus (Bunyaviridae) infections in rodents from Orange and San Diego Counties, California. Am J Trop Med Hyg 1999; 60: 75-84. 64. Gavrilovskaya I, LaMonica R, Fay ME, Hjelle B, Schmaljohn C, Shaw R, Mackow ER. New York 1 and Sin Nombre viruses are serotypically distinct viruses associated with hantavirus pulmonary syndrome. J Clin Microbiol 1999; 37: 122-126. 65. Bharadwaj M, Lyons CR, Wortman IA, Hjelle B. Intramuscular inoculation of Sin Nombre hantavirus cDNAs induces cellular and humoral immune responses in BALB/c mice. Vaccine 1999; 17: 2836-43. 66. Zavasky D-M, Hjelle B, Peterson MC, Denton RW, Reimer L. Acute infection with Sin Nombre hantavirus without pulmonary edema. Clin Infect Dis 1999; 29: 664-6. 67. Terajima M, Hendershot JD, Kariwa H, Koster FT, Hjelle B, Goade D, DeFronzo MC, Ennis FA. High levels of viremia in patients with the hantavirus pulmonary syndrome. J Infect Dis 1999; 180: 2030-4. 68. Pai RK, Bharadwaj M, Levy H, Overturf G, Goade D, Wortman IA, Nofchissey R, Hjelle B. Absence of infection of a neonate after possible exposure to Sin Nombre hantavirus in breast milk. Clin Infect Dis 1999; 29: 1577-9. 69. Botten J, Nofchissey R, Ahern H, Rodriguez-Moran P, Wortman IA, Goade D, Yates T, Hjelle B. Outdoor facility for quarantine of wild rodents infected with hantavirus. J Mammal 2000; 81: 250-9. 70. Ramos MM, Hjelle B, Overturf GD. Sin Nombre hantavirus disease in a 10-year-old boy and his mother. Pediatr Infect Dis J 2000; 19: 248-50. 71. Biggs JR, Bennett K, Mullen M, Haarmann TK, Salisbury M, Robinson RJ, Keller D, Torrez-Martinez N, Hjelle B. Relationship of ecological variables to Sin Nombre hantavirus seroprevalence in populations of deer mice. J Mammal 2000; 81: 676-82.

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72. Biggs JR., Bennett KD, Torrez-Martinez N, Hjelle BL. Sin Nombre virus antibody seroprevalence in rodents of north-central New Mexico. Southwestern Naturalist 2000; 45: 61-6. 73. Hjelle B, Glass GE. Outbreak of hantavirus infection in the Four Corners region of the US in the wake of the 1997-98 El Niño-Southern Oscillation. J Infect Dis 2000; 181:1569-73. (http://www.journals.uchicago.edu/JID/journal/issues/v181n5/991334/991334.html) (Cited 51 times by July 08) 74. Vetcha S, Abdel-Hamid I, Atanassov P, Wilkins E, Hjelle B. Portable biosensor for the fast amperometric detection of anti-hantavirus antibodies. Electroanalysis 2000; 12; 1034-8. 75. Bharadwaj M, Nofchissey R, Goade D, Koster F, Hjelle B. Humoral immune responses in the hantavirus cardiopulmonary syndrome. J Infect Dis 2000; 182: 43-8. (http://www.journals. uchicago.edu/JID/journal/issues/v182n1/000146/000146.html) (Cited 47 times by July 08) 76. Botten J, Mirowsky K, Kusewitt D, Bharadwaj M, Yee J, Ricci R, Feddersen RM, Hjelle B. Experimental infection model for Sin Nombre hantavirus in the deer mouse (Peromyscus maniculatus). Proc Natl Acad Sci USA 2000; 97: 10578-83. (http://www.pnas.org/cgi/ content/full/97/19/10578) (Cited 48 times by July 08) 77. Gonzalez LM, Lindsey AE, Hjelle B, Dominguez D, Brown J, Goade D, Jonsson CB. Prevalence of antibodies to Sin Nombre virus in humans living in rural areas of southern New Mexico. Virus Res; 2001; 74: 177-9. 78. Botten J, Ricci R, Hjelle B. Establishment of a deer mouse (Peromyscus maniculatus rufinus) breeding colony from wild-caught founders. Comp Med 2001; 51: 291-5. 79. Goade DE, Nofchissey RA, Kusewitt DF, Hjelle B, Kreisel J, Moore J, Lyons CR. Ultraviolet light induces reactivation in a murine model of cutaneous herpes simplex virus-1 infection. Photochem Photobiol 2001; 108: 108-14. 80. Koster F, Foucar K, Hjelle B, Scott A, Chong Y-Y, Larson R, McCabe M. Rapid presumptive diagnosis of hantavirus cardiopulmonary syndrome by peripheral blood smear review. Am J Clin Path 2001; 116: 665-72. 81. Romano-Lieber NS, Yee J, Hjelle B. Serologic survey for hantavirus infections among wild animals in rural areas of São Paulo State, Brazil. Rev Inst Med trop S Paulo 2001; .43: 325-7.

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82. Ramos MM, Overturf GD, Crowley MR, Rosenberg RB, Hjelle B. Infection with Sin Nombre hantavirus: clinical presentation and outcome in children and adolescents. Pediatrics 2001; 108: U39-U44. 83. Vetcha S, Wilkins E, Yates T, Hjelle B. Rapid and sensitive handheld biosensor for detection of hantavirus antibodies in wild mouse blood samples under field conditions. Talanta 2002; 58: 517-28. 84. Bharadwaj M, Mirowsky K, Botten J, Masten B, Yee J, Lyons CR, Hjelle B. Genetic vaccines protect against Sin Nombre hantavirus challenge in the deer mouse (Peromyscus maniculatus). J Gen Virol 2002; 83: 1745-51. 85. Botten J, Mirowsky K, Ye C, Gottlieb K, Saavedra M, Ponce L, Hjelle B. Shedding and intracage transmission of Sin Nombre hantavirus in the deer mouse (Peromyscus maniculatus) model. J Virol 2002; 76: 7587-94. 86. Davis IC, Zajac AJ, Nolte KB, Botten J, Hjelle B, Matalon S. Elevated generation of reactive oxygen/nitrogen species in hantavirus cardiopulmonary syndrome. J Virol 2002; 76: 8347-59. 87. Botten J, Mirowsky K, Kusewitt D, Ye C, Gottlieb K, Prescott J, Hjelle B. Persistent Sin Nombre virus infection in the deer mouse (Peromyscus maniculatus) model: sites of replication and strand specific expression. J Virol 2003; 77: 1540-50. 88. Klempa B, Schmidt HA , Ulrich R, Kaluz S , Labuda M , Meisel H, Hjelle B, Krüger DH. Genetic interactions between distinct Dobrava hantavirus subtypes of Apodemus agrarius and A. flavicollis in nature. J Virol 2003; 77: 804-9. 89. Yee J, Wortman IA, Nofchissey R, Goade D, Bennett SG, Webb JP, Irwin W, Hjelle B. Rapid and simple method for screening wild rodents for antibodies to Sin Nombre hantavirus. J Wildlife Dis 2003; 39: 271-7. 90. Armien B, Pascale JM, Bayard V, Carlos Munoz C, Itza Mosca I, Guerrero G, Armien A, Quiroz E, Castillo Z, Yamizel Zaldivar Y, Gracia F, Hjelle B, Koster F. high seroprevalence of hantavirus infection on the Azuero Peninsula of Panama. Am J Trop Med Hyg 2004; 70: 682-7. 91. Biser JA, Vogel LA, Berger J, Hjelle B, Loew SS. An investigation into the effects of heavy metals on immunocompetence of white-footed mice (Peromyscus leucopus). J Wild Dis 2004; 40: 173-84.

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92. Ye C, Prescott J, Nofchissey R, Goade D, Hjelle B. Neutralizing antibodies and Sin Nombre virus RNA after recovery from hantavirus cardiopulmonary syndrome. Emerg Infect Dis 2004;10: 478-82. http://www.cdc.gov/ncidod/eid/vol10no3/02-0821.htm 93. Tager Frey M, Vial PC, Castillo CH, Godoy PM, Hjelle B, Ferres MG. Hantavirus prevalence in the IX region of Chile. Emerg Infect Dis 2003; 9: 827-32. 94. Alam MK, Timlin JA, Martin LE, Williams D, Lyons CR, Garrison K, Hjelle B. Spectroscopic evaluation of living murine macrophage cells before and after activation using attenuated total reflectance infrared spectroscopy. Vibrat Spectroscopy 2004; 34: 3-11. 95. Mertz GJ, Miedzinski L, Goade D, Pavia A, Hjelle B, Hansbarger CO, Levy H, Koster FT, Lindemulder A, Wang W, Riser L, Fernandez H, Whitley RJ, the Collaborative Antiviral Study Group. Placebo-controlled, double-blind trial of intravenous ribavirin for the treatment of hantavirus cardiopulmonary syndrome in North America. Clin Infect Dis 2004; 39 1307-13. 96. Schmidt J, Meisel H, Hjelle B, Krüger D, Ulrich R. Development and evaluation of serological assays for detection of human hantavirus infections caused by Sin Nombre virus. J Clin Virol 2005; 33: 247-53. 97. Safronetz D, Lindsay R, Dibernardo A, Hjelle B, Xiao R, Artsob H, Drebot MA. A preliminary study of the patterns of Sin Nombre viral infection and shedding in naturally infected deer mice (Peromyscus maniculatus). Vec Borne Zoon Dis 2005; 5: 127-32. 98. Gardner SL, Von Essen S, Berger J, Hjelle B. Low seroprevalence among farmers from Nebraska and vicinity suggests low level of human exposure to Sin Nombre virus. J Agromedicine. 2005; 10: 59-61. 99. Larson RS, Brown D, Ye C, Hjelle B. Peptide antagonists that inhibit Sin Nombre and Hantaan virus entry through the β3 integrin receptor. J Virol 2005; 79: 7319-26. (Journal of Virology Spotlight article) 100. Schmidt J, Meisel H, Capria SG, Petraityte R, Lundkvist Å, Hjelle B, Vial PA, Padula P, Krüger D, Ulrich R. Serological assays for the detection of human Andes hantavirus infections based on its yeast-expressed nucleocapsid protein. Intervirology 2006; 49: 173-84. 101. Valdivieso F, Vial P, Ferres M, Ye C, Goade D, Cuiza A, Hjelle B. Neutralizing antibodies in survivors of Sin Nombre and Andes hantavirus infection. Emerg Infect Dis 2006; 12: 166-8.

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102. Prescott J, Ye C, Sen G, Hjelle B. Induction of innate immune response genes by Sin Nombre hantavirus does not require viral replication. J Virol 2005; 79: 15007-15. 103. Xiao R, Yang S, Koster F, Ye C, Stidley C, Hjelle B. Sin Nombre viral RNA load in patients with the hantavirus cardiopulmonary syndrome. J Infect Dis 2006; 194: 1403-9. 104. Oko L, Aduddell-Swope B, Willis D, Hamor R, Coons TA, Hjelle B, Schountz T. Profiling helper T cell subset gene expression in the deer mouse (Peromyscus maniculatus). BMC Immunology 2006, 7:18-25. 105. Safronetz D, Lindsay R, Hjelle B, Medina RA, Mirowsky-Garcia K, Artsob H, Drebot MA. Use of IgG avidity to indirectly monitor epizootic transmission of Sin Nombre virus in deer mice (Peromyscus maniculatus). Amer J Trop Med Hyg 2006; 75: 1135-9. 106. Mir MA, Brown B, Duran WA, Hjelle BL, Panganiban AT. Hantavirus N protein exhibits genus-specific recognition of the vRNA panhandle. J Virol 2006; 80: 11283-92. 107. Medina R, Mirowsky-Garcia K, Hutt J, Hjelle B. Ribavirin, human convalescent plasma and anti-β3 integrin antibody inhibit infection by Sin Nombre virus in the deer mouse model. J Gen Virol 2007; 88: 493-505. 108. Ferrés M, Vial P, Marco C, Yañez L, Godoy P, Castillo C, Hjelle B, Delgado I, Lee S-J, Mertz GJ. Prospective evaluation of household contacts of persons with hantavirus cardiopulmonary syndrome in Chile. J Infect Dis 2007; 195: 1563-71. 109. Velappan N, Martinez JS, Valero R, Chasteen L, Ponce L, Bondu-Hawkins V, Kelly C, Pavlik P, Hjelle B, Bradbury, ARM. Selection and characterization of scFv antibodies against the Sin Nombre hantavirus nucleocapsid protein. J Immunol Meth 2007; 321: 60-9. 110. Hall PR, Malone L, Sillerud LO, Ye C, Hjelle BL, Larson RS. Characterization and NMR solution structure of a novel cyclic pentapeptide inhibitor of pathogenic hantaviruses. Chem Biol Drug Des 2007; 69: 180-90. 111. Prescott J, Hall P, Bondu-Hawkins V, Ye C, Hjelle B. Early innate immune responses to Sin Nombre hantavirus occur independently of IFN regulatory factor 3, characterized pattern recognition receptors, and viral entry. J Immunol 2007; 179:1796-802. 112. Sitdikov RA, Wilkins ES, Yates T, Hjelle B. Detection of hantavirus using a new miniaturized biosensor device. J Appl Res Clin Exper Ther 2007; 7: 86-107.

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113. Schountz T, Prescott J, Cogswell A, Oko L, Mirowsky K-M, Galvez Fuenzalida A, Hjelle B. Regulatory T cell-like responses in deer mice persistently infected with Sin Nombre virus. Proc Natl Acad Sci USA 2007; 104: 15496-501. 114. Bisoffi M, Hjelle B, Brown DC, Edwards TL, Brozik SM, Branch DW, Bondu-Hawkins VS, Larson RS. Detection of viral bioagents using a shear horizontal surface acoustic wave biosensor. Biosens Bioelectron 2008; 23: 1397-403. 115. Hall PR, Hjelle B, Brown DC, Ye C, Bondu-Hawkins V, Kilpatrick KA, Larson RS. Multivalent presentation of anti-hantavirus peptides on nanoparticles enhances infection blockade. Antimicrob Agents Chemother 2008; 52: 2079–88. 116. Mir MA, Duran WA, Hjelle B, Ye C, Panganiban AT. Storage of cellular 5’ mRNA caps in P bodies. Proc Natl Acad Sci USA 2008; 105: 10294-9. 117. Manigold T, Martinez J, Lazcano X, Ye C, Schwartz S, Cuiza A, Valdivieso F, Hjelle B, Vial P. Case report: T-cell responses during clearance of Andes virus from blood cells 2 months after severe hantavirus cardiopulmonary syndrome. J Med Virol. 2008; 80: 1947-51. 118. Medina RA, Torres-Perez F, Galeno H, Navarrete M , Vial PA, Palma RE, Ferres M, Cook JA, Hjelle B. Ecology, genetic diversity and phylogeographic structure of Andes virus in humans and rodents in Chile. J Virol 2009; 83: 2449-59. (30 Dec 2008 epub ahead of print). 119. Armién AG, Armién B, Koster F, Pascale JM, Avila M, Gonzalez P, De La Cruz M, Zaldivar Y, Mendoza Y, Gracia F, Hjelle B, Lee S-J, Yates TL, Salazar–Bravo J. Hantavirus infection and habitat associations among rodent populations in agroecosystems of Panama: implications for human disease risk. Amer J Trop Med Hyg 2009; 81: 59-66. 120. Lordemann AG, Hjelle B, Theegarten D, Grabellus F, Schmid KW, Hoyer PF, Vester U, Becker JU. Young man with kidney failure and hemorrhagic interstitial nephritis (Teaching Case). Am J Kid Dis 2009; 24 Jun epub ahead of print. 121. Torres-Pérez F, Palma RE, Hjelle B, Ferrés M, Cook JA. Andes virus infections in the rodent reservoir and in humans vary across contrasting landscapes in Chile. Infect Genet Evol 2009; 24 Jul. [Epub ahead of print] 122. Hall PR, Hjelle B, Njus H, Ye C, Bondu-Hawkins V, Brown DC, Kilpatrick KA, Larson RS. Phage display selection of cyclic peptides that inhibit Andes virus infection. J Virol 2009; 83: 8965-9.

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123. Torres-Pérez F, Wilson L, Collinge SK, Harmon H, Ray C, Medina RA, Hjelle B. Symptomatic Sin Nombre virus infections contracted by field workers in Colorado. Emerg Infect Dis 2010; 16: 308-10. 124. Manigold T, Mori A, Graumann R, Llop E, Simon V, Valdivieso F, Castillo C, Hjelle B, Vial P. Highly differentiated, resting Gn-specific memory CD8+ T cells persist years after infection by Andes hantavirus. PLoS Pathogen 2010; 19: e1000779. 125. Czuchlewski DR, Brackney M, Ewers C, Manna J, Fekrazad MH, Martinez A, Nolte KB, Hjelle B, Rabinowitz I, Curtis BR, McFarland JG, Baumbach J, Foucar K. Clinicopathologic features of agranulocytosis in the setting of levamisole-tainted cocaine. Am J Clin Path 2010; 133: 466-72, 126. Buranda T, Wu Y, Perez D, Jett SD, Bondu-Hawkins V, Ye C, Edwards B, Larson RS, Hall P, Lopez GD, Sklar LA, Wandinger-Ness A, Hjelle B. Recognition of DAF and αvβ3 by inactivated hantaviruses, towards development of high throughput screening flow cytometry assays. Anal Biochem 2010; 402: 151-60. 127. Pesko KN, Torres-Perez F, Hjelle B, Ebel GD. Molecular epidemiology of Powassan virus in North America. J Gen Virol 2010; 14 July (Epub ahead of print). 128. Scott JC, Brackney DE, Campbell CL, Bondu-Hawkins V, Hjelle B, Ebel GD, Olson KE, Blair CD. Comparison of dengue virus type 2-specific small RNAs from RNA interference-competent and –incompetent mosquito cells. PLoS Negl Trop Dses 2010; 4: e848. 129. Prescott J, Hall P, Acuna-Retamar M, Ye C, Wathelet MG, Ebihara H, Feldmann H, Hjelle B. New World hantaviruses activate IFN-lambda production in type I IFN-deficient Vero E6 cells. PLoS One 2010; 17;5(6):e11159. PMID: 20567522 130. Hall PR, Leitão A, Ye C, Kilpatrick K, Hjelle B, Oprea TI, Larson RS. Small molecule inhibitors of hantavirus infection. Bioorg Medicinal Chem Let 2010; 20: 7085-91. 131. Kucinskaite-Kodze I, Petraityte-Burneikiene R, Zvirbliene A, Hjelle B, Medina RA, Alma Gedvilaite A, Razanskiene A, Schmidt-Chanasit J, Mertens M, Padula P, Sasnauskas K, Ulrich RG. Characterization of monoclonal antibodies against hantavirus nucleocapsid protein and their use for immunohistochemistry on rodent and human samples. Arch Virol 2011; 56: 443-56. 132. Torres-Pérez F, Palma RE, Hjelle B, Holmes EC, Cook JA. Spatial but not temporal co-divergence of a virus and its mammalian host. Molec Ecol 2011; 20: 4109-22.

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133. Armien B, Pascale JM, Munoz C, Lee S-J, Choi KL, Avila M, Broce C, Armien AG, Gracia G, Hjelle B, Koster F. Incidence rate for hantavirus infections without pulmonary syndrome, Panama. Emerg Inf Dis 2011; 17: 1936-9. 134. Oprea TI, Bauman JE, Bologa CG, Buranda T, Chigaev A, Edwards BS, Jarvik JW, Gresham HD, Haynes MK, Hjelle B, Hromas R, Hudson L, Mackenzie DA, Muller CY, Reed JC, Simons PC, Smagley Y, Strouse J, Surviladze Z, Thompson T, Ursu O, Waller A, Wandinger-Ness A, Winter SS, Wu Y, Young SM, Larson RS, Willman C, Sklar LA. Drug repurposing from an academic perspective. Drug Disc Today: Ther Strategies 2011; 359: 2-9. SUBMITTED/IN PREPARATION INVITED REVIEWS, EDITORIALS AND COLLABORATIVE GROUP PAPERS: 1. Hjelle B. Human T-cell leukemia/lymphoma viruses. Life cycle pathogenicity epidemiology and diagnosis. Arch Pathol Lab Med 1991;115:440-50. (peer reviewed) (Cited 47 times by Feb 2007) 2. Hjelle B. Hantaviruses with emphasis on Four Corners hantavirus. World wide web virology server of University of Wisconsin (http://www.bocklabs.wisc.edu/ed/hanta.html) October 1994; revised March 1995. 3. Jenison S, Hjelle B. Hantavirus testing at the University of New Mexico. Epidemiology Reports of the New Mexico Department of Health. May 1994 pp 1-2. 4. Duchin JS, Koster FT, Peters CJ, Simpson GL, Tempest B, Zaki SR, Ksiazek TG, Rollin P, Nichol S, Umland E, Moolenaar RL, Reef SE, Nolte KB, Gallaher MM, Butler JC, Breiman RF, and the Hantavirus Study Group. Hantavirus pulmonary syndrome: a clinical description of 17 patients with a newly recognized disease. N Engl J Med 1994;330:949-955. (peer reviewed) (Cited 329 times by July 2008) 5. Hjelle B. Hantavirus pulmonary syndrome. Newsletter of the College of American Pathologists 1994; 8:4. 6. McLaughlin JC, Foucar K, Nolte KB, Simpson GL, Hjelle BL, Young SA, Umland E, Koster FT. Hantavirus infections. GAMA Reports a publication of the Greater Albuquerque Medical Association 1993 vol. XIV pp. 4-7.

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7. Hjelle B. Human T-cell lymphotropic viruses: a transfusion medicine perspective. Transfusion Medicine Audio Update 1992;4 (6) (July) ISSN 1052-3197. 8. Hjelle B. HTLV-II in the western United States. Western J Med 1994;160:540-4. (peer reviewed) 9. Jenison S, Hjelle B, Simpson S, Hallin G, Feddersen R, Koster F. Hantavirus pulmonary syndrome: clinical diagnostic and virologic aspects. Sem Respir Infect 1995; 10: 259-69. (peer reviewed) 10. Hjelle B, Jenison SA, Goade D,E Green WB, Feddersen RM, Scott AA. Hantaviruses: clinical microbiologic and epidemiologic aspects. Crit Rev Clin Lab Sci 1995;32:469-508. (peer reviewed) 11. Hjelle B. Frequently-asked-questions about hantavirus pulmonary syndrome and hemorrhagic fever with renal syndrome. http://www.outbreak.org/cgi-unreg/dynaserve. exe/Hantavirus/FAQ.html. Outbreak web page. 1996. 12. Schmaljohn C, Hjelle B. Hantaviruses: a global disease problem. Emerg Infect Dis 1997; 3: 95-104. http://www.cdc.gov/ncidod/EID/vol3no2/schmaljo.htm (PMID 9204290; cited 514 times by September 2011) 13. Mertz GJ, Hjelle BL, Bryan RT. Hantavirus infection. Adv Intern Med 1997; 42: 369-421. 14. Keller D, Ettestad P, Sewell CM, Rains R, Englender S, Woods T, Pape J, Tanda D, Reynolds J, Hoffman R, Mertz G, Scully G, Mapel D, Koster F, DeLury J, Hansbarger C, Hjelle B, Yates T, Iralu J, Freeman C, Hroch B, Nunes A, Loretto D, Peter D, Fulgham R, Courtois L, Mattson M, Charleston R, Cheek J. Hantavirus pulmonary syndrome : Colorado and New Mexico 1998. MMWR 1998; 47: 449-52. 15. Alam MK, Timlin JA, Martin LE, Hjelle B, Lyons R, Garrison K. Spectroscopic detection of pathogens. Sandia Report SAND2000; 2929: 1-14. 16. Hjelle B. Epidemiology and diagnosis of hantavirus infections. In: UpToDate, Rose, BD (Ed), UpToDate, Wellesley, MA, 2003. (Updated 2005, 2008). 17. Hjelle B, Lyons R. Biosignature diagnosis and rapid genetic vaccine paradigms for defense against agents of bioterrorism. In: Proceedings 2nd Ann Workshop for Unif Sci & Technol for Reducing Biol Threats & Countering Terrorism (BTR 2002; B. Daniels, A. Sobel and R. Duncan, eds.) Albuquerque, NM, 2002.

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18. Hjelle B. Vaccines against hantaviruses. Expert Rev Vaccines 2002; 1: 89-100. (peer reviewed) 19. Drebot MA, Henchal E, Hjelle B, LeDuc JW, Repik PM, Roehrig JT, Schmaljohn CS, Shope RE, Tesh RB, Weaver SC, Calisher CH. Improved clarity of meaning from the use of both species names and common (vernacular) virus names in virological literature. Arch Virol 2002; 147: 2465-72. (peer reviewed) 20. Ulrich R, Hjelle B, Pitra C, Krüger DH. Emerging viruses: the case “hantavirus”. Intervirology 2002; 45: 318-27. 21. Hjelle, B. Pathogenesis of hantavirus infections. In: UpToDate, Rose, BD (Ed), UpToDate, Wellesley, MA, 2004. (Updated 2005, 2008). 22. Hjelle B. Hantavirus diagnostic testing. Newsletter for TriCore Reference Laboratories, August 2004. 23. Hjelle B and Foucar K. Diagnostic algorithms for hantavirus cardiopulmonary syndrome. Technical Notes series, TriCore Reference Laboratories, July 2004. 24. Hjelle B. Hantavirus cardiopulmonary syndrome. In: UpToDate, Rose, BD (Ed), UpToDate, Wellesley, MA, 2005. (updated 2006 and 2008). 25. Puerta H, Cantillo C, Mills J, Hjelle B, Salazar-Bravo J, Mattar S. Hantavirus del Nuevo Mundo: Ecologia y epidemiologia de un virus emergente en Latinoamerica. Medicina (Buenos Aires) 2006; 66: 343-56. (Spanish). 26. Mertz GJ, Hjelle B, Crowley M, Iwamoto G, Tomicic V, Vial P. Diagnosis and treatment of New World hantavirus infections. Curr Opin Infect Dis 2006; 19: 437-42. 27. Hjelle B, Torres-Perez F. Hantaviruses in the Americas and their role as emerging pathogens. Viruses 2010; 2: 2559-86. 28. Arrigo NC, Briese T, Calisher CH, Drebot MA, Hjelle B, LeDuc JW, Powers AM, Repik PM, Roehrig JT, Schmaljohn CS, Tesh TB, Weaver SC. Recommendations for publication of viral genetic data and sample access for novel viruses and strains. Am J Trop Med Hyg 2012; 86: 189-91. BOOK CHAPTERS:

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1. Hjelle B, Swenson SG, Simon TL. In: Fenoglio-Preiser C (ed) Testing in the blood bank Mosby Yearbook of Pathology Advances in Pathology 1991;4:75-105. 2. Hjelle B. Detection of human T-cell leukemia viruses. Chapter 4. In: Becker Y and Darai G (eds) Diagnosis of Human Viruses by Polymerase Chain Reaction (PCR) Technology Frontiers in Virology Vol. 1 Springer-Verlag New York and Heidelberg 1992. 3. Hjelle B. Outbreak of hantavirus pulmonary syndrome in the United States: detection of Four Corners virus by PCR. Chapter 45 pp. 403-7 in Becker Y and Darai G (eds). PCR: Protocols for Diagnosis of Human and Animal Virus Diseases Frontiers in Virology 1995 New York and Heidelberg. 4. Hjelle B. Transfusion-transmitted HTLV-I and HTLV-II. Chapter 68 pp. 709-16 in: Rossi EC, Simon TL, Moss GS, and Gould SA: Principles of Transfusion Medicine second edition Williams and Wilkins Baltimore Maryland 1995. 5. Jenison S, Hjelle B. Human immunodeficiency viruses and the acquired immunodeficiency syndrome. Chap. 4 pp. 40-56 In: Glew R and Ninomiya Y eds. Clinical Studies in Medical Biochemistry. 2nd edition. Oxford University Press 1996. 6. Hjelle B. Detection of Sin Nombre hantavirus by reverse transcription-PCR. P.1 pp. 91-99 in: Persing DH (ed) Selected PCR Applications for Emerging Infectious Diseases suppl. to Diagnostic Molecular Microbiology American Society for Microbiology Press 1996 Washington. 7. Hjelle B. Virus detection and identification with genetic tests. Chapter VIII pp. 132-7 in: Lee HW Calisher C Schmaljohn CS (eds.) Manual of Hemorrhagic Fever with Renal Syndrome and Hantavirus Pulmonary Syndrome World Health Organization Geneva 1999. 8. Hjelle B, Torrez-Martinez N, Bharadwaj M., Western blot and strip immunoblot assays for hantavirus. Chapter VII pp. 122-32 in: Lee HW, Calisher C, Schmaljohn CS (eds.) Manual of Hemorrhagic Fever with Renal Syndrome and Hantavirus Pulmonary Syndrome World Health Organization Geneva 1999. 9. Hjelle B. Hantavirus pulmonary syndrome. Chapter 21 pp. 421-442 in: Lennette EH and Smith TF (eds.) Laboratory Diagnosis of Viral Infections Marcel Decker Inc. third edition New York 1999. 10. Hjelle BL, Gonzales-Scarano F. Bunyaviruses and disease. Chapter 32 pp 521-35 in: Cunningham MW and Fujinami RS (eds) Effects of Microbes on the Immune System Lippincott Williams & Wilkins 1999 688 pp.

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11. Hjelle B. Hantaviruses and hantavirus cardiopulmonary syndrome in the Americas. Pages 55-62 in: JF Saluzzo, B Dodet (eds) Factors in the Emergence and Control of Rodent-Borne Viral Diseases: Hantaviral and Arenal 1999 Elsevier Paris. 12. Mertz GJ, Hjelle B, Williams TM, Koster FT. Host responses in the hantavirus cardiopulmonary syndrome. Pages 133-7 in: JF Saluzzo B Dodet (eds) Factors in the Emergence and Control of Rodent-Borne Viral Diseases: Hantaviral and Arenal 1999 Elsevier Paris. 13. Hjelle B. Rodent-borne viruses. Chapter 39 pp. 568-78 in: S Specter G Lancz (eds) Clinical Virology Manual 3rd Edition 2000 American Soc for Microbiology Press Washington. 14. Hjelle B, Yates T. Modeling hantavirus maintenance and transmission in rodent communities. Chapter 6 pp. 77-90 in: C Schmaljohn and S Nichol (eds) Current Topics in Microbiology and Immunology (Hantaviruses) 2001 Springer-Verlag Heidelberg. 15. Roth P, Hjelle B, Gaffney J. Biomedical aspects of bioterrorism and a call to action. Pp. 82-85. In: Emerging Technologies: Recommendations for Counter-Terrorism Institute for Security Technology Studies Dartmouth College Dartmouth NH 2001. 16. Koster F, Hjelle B. The hantaviruses. In Infectious Diseases Third Edition eds. SL Gorbach JG Bartlett NR Blacklow. WB Saunders Co, Philadelphia. Chapter 245, 2004 pp. 2023-2031. 17. Hjelle B, Young SA. Hantavirus infections. Section J Viral Diseases Chapter 86 in Manual of Molecular and Clinical Laboratory Immunology, 7th Edition. SC Specter et al., eds. ASM Press, Washington, 2006. 18. Hjelle B, Torres-Perez F. Rodent-borne viruses. Chapter 35 in: S Specter, R Hodinka, S Young, and D Wiedbrauk (eds) Clinical Virology Manual 4th Edition 2009 American Soc for Microbiology Press Washington, DC. 19. Vaheri, A, Mills, JN, Spiropoulou, CF, Hjelle, B. Hantaviruses. In "Zoonoses - biology, clinical practice and public health" 2nd Edition, (SR Palmer, Lord Soulsby, David Brown, and Paul Torgerson, Editors). Oxford University Press. Oxford. U.K. 2010 (in press). LETTERS:

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1. Hjelle B, Swenson S, Cyrus S. Evidence for sexual transmission of human T lymphotropic virus type II (HTLV-II). Ann Int Med 1992;116:90-1. (Cited 39 times by July 2008) 2. Wilson C, Hjelle B, Jenison S. A probable case of hantavirus pulmonary syndrome that occurred in New Mexico in 1975. Ann Int Med 1994;120:813. 3. Song J-W, Baek L-J, Gajdusek DC, Yanagihara R, Gavrilovskaya I, Luft BJ, Mackow ER, Hjelle B. Isolation of pathogenic hantavirus from white footed mouse (Peromyscus leucopus). Lancet 1994;344:1637. (Cited 58 times by July 2007) 4. Torrez-Martinez N, Hjelle B. Enzootic of Bayou hantavirus in rice rats (Oryzomys palustris) in 1983. Lancet 1995; 346: 780-1. (Cited 23 times by July 2008) 5. Hjelle B, Torrez-Martinez N, Koster FT. Hantavirus pulmonary syndrome-related virus from Bolivia. Lancet 1996; 347:57. 6. Kennon C, Overturf G, Hjelle B. Granulocyte-colony-stimulating factor and neonatal infection : reply . J Peds 1997; 130: 845-846. 7. Rodriguez-Moran P, Kelly C, Williams TM, Hjelle B. Hantavirus infection in the Four Corners region of USA in 1998. Lancet 1998; 352: 1353. 8. Hjelle B, Bennett S Webb J. Hantavirus nomenclature. Am J Trop Med Hyg 2000; 61: 864. 9. Camaioni M, Botten J, Hjelle B, Loew SS. Hantavirus seroconversion of wild-caught Peromyscus during quarantine. Emerg Infect Dis 2001; 7: 14-5. http://www.cdc.gov/ncidod/eid/vol7no3/camaioni_letter.htm 10. Hjelle B. Genetic and serotypic characterization of Sin Nombre-like viruses in Canadian Peromyscus maniculatus mice (invited commentary). Virus International 2002 (http://www.virusint.com/virusint/show/). 11. Klempa B, Ulrich R, Meisel H, Krüger DH, Schmidt HA , Kaluz S , Labuda M , Hjelle B. Genetic interaction between Dobrava and Saaremaa hantaviruses: Now or millions of years ago? (Authors’ reply). J Virol 2003; 77: 7157-8.

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ABSTRACTS: 1. Hjelle BL, Phillips JA III, Seeburg PH, Kazazian HH Jr., Patterns of DNA methylation within human growth hormone (GH) and chorionic somatomammotropin genes in expressing and non-expressing tissues. Am J Hum Genet 1981;33:45A (abstr). 2. Phillips JA III, Hjelle BL, Seeburg PH, Plotnick LP, Migeon CJ, Zachmann M. Heterogeneity in the molecular basis of familial isolated growth hormone deficiency (IGHD). Am J Hum Genet 1981;33:52A (abstr). 3. Riverola MA, Phillips JA III, Migeon CJ, Hjelle BL. Phenotypic heterogeneity in familial isolated growth hormone deficiency type A. Ped Res 1982;16:43A (abstr). 4. Liu E, Hjelle B, Bishop JM. Characterization of a myc immortalized cell line derived from rat embryo cells. Blood 1985;66 Suppl.1:846 (abstr). 5. Liu E, Hjelle B, Bishop JM. Transforming genes in chronic myelogenous leukemia (CML). Blood 1985;66 Suppl. 1:847 (abstr). 6. Liu E, Hjelle B, Morgan R, Bishop JM. The role of mutant ras genes in preleukemic states. Blood 1987;70 Suppl.1:282 (abstr). 7. Hjelle B, Evans M, Yen T-SB, Guis M, Garovoy M, Edman J. Undifferentiated tumor of donor origin in a renal transplant recipient. Am J Clin Pathol 1988;90:500 (35A) (abstr). 8. Hjelle B, Busch M. Direct methods for detection of HIV-1 infection. Internal Med Digest 1990;4:108-9 (abstr). 9. Hjelle B, Mills R, Mertz G, Swenson S. Transmission of HTLV-II via blood transfusion. Transfusion 1990;30:S699 (abstr). 10. Swenson SG, Cyrus S, Hjelle B. Western immunoblot patterns in HTLV-II-infected individuals. Transfusion 1990;30:S701 (abstr). 11. Hjelle B, Mills R, Mertz G, Swenson S. Frequent isolation of HTLV-II from HTLV-I/II-seropositive blood donors. Transfusion 1990;30:S700 (abstr). 12. Hjelle B, Mills R, Mertz G, Swenson S, Key C, Allen S. Low pathogenicity of HTLV-II determined by cancer epidemiology of first known endemic population. ACP/ASIM New Mexico Scientific Meeting December 8 1990 (abstr).

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13. Hjelle B, Miller V, Scalf R, Tarnower A. Phenotypic and structural variation among tax2 alleles from "endemic" HTLV-II: Sequence analysis of presumed apathogenic isolates. Fourth Intl Conf on Retroviruses: HTLV (poster discussion T-IX-7) February 12 1991. 14. Hjelle B, Mills R, Swenson S, Mertz G, Key C, Allen S. Incidence of hairy cell leukemia mycosis fungoides and chronic lymphocytic leukemia in first known HTLV-II-endemic population. Oncology Digest 1991;4:26-7 (abstr). 15. Davis LE, Hjelle BL, Miller VE, Palmer DL, Llewellyn AL, Merlin TL, Young SA, Mills R, Wachsman W, Wiley CA. Early viral invasion of brain in iatrogenic human immunodeficiency virus infection. Ann Neurol 1991;30:314-5 (abstr. P314). 16. Cyrus S, Hjelle B, Swenson SG, Lal R. Three methods for serologic distinction of HTLV-I and -II infection. Transfusion 1991;31:S144 (abstr). 17. Hjelle B, Appenzeller O, Jahnke R, Berger M. Peripheral nerve dysfunction in blood donors with longstanding HTLV-II infection. Transfusion 1991;31:S18 (abstr). 18. Hjelle B, Mills R, Cyrus S, Swenson SG. Infection is present in a high fraction of HTLV Western blot indeterminate donors. Transfusion 1991;31:S16 (abstr). 19. Hjelle B, Mills R. Coculture assay for human T-cell leukemia-lymphoma viruses. Transfusion 1991;31:S17 (abstr). 20. Hjelle B, Mills R, Ross G, Alexander S. Identification of two patients with familial spastic paraparesis associated with HTLV-II infection Blood 1991;78 (Suppl 1):1443 (abstr). 21. Hjelle B, Appenzeller O, Jahnke R, Ross G, Mills R, Alexander S, Torrez-Martinez N. HTLV-II infection is associated with familial spastic paraparesis and other neurologic disorders. Neurology 1992;42(Suppl 3):253S (abstr). 22. Wilson C, Hjelle B. Lower estimate of HTLV ELISA failure rate in blood donors. Proceedings of the Fifth Intl Conference on Human Retrovirology: HTLV May 11-13 1992 Kumamoto Japan (abstr W-61 workshop session). 23. Hjelle B, Appenzeller O, Mills R, North C, Alexander S. Neurologic and immune diseases in a population with endemic HTLV-II infection in the southwestern US: association with negative HTLV-I antibody screens. Proceedings of the Fifth Intl Conference on Human Retrovirology: HTLV May 11-13 1992 Kumamoto Japan (abstr O-25 oral presentation).

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24. Hjelle B, Mills R, Goldsmith C. Diagnostic application of primary isolation of HTLV and use in detecting infection in seroindeterminate donors. Proceedings of the Fifth Intl Conference on Human Retrovirology: HTLV May 11-13 1992 Kumamoto Japan (abstr W-71 workshop session). 25. Kennon C, Young S, Brown D, Schammel C, Hjelle B. Human herpesvirus-6 antibody in preterm infants: Rapid decrease in titers after phlebotomy. Transfusion 1992;32:S200 p. 52S (abstr). 26. Hjelle B, Wilson C, Cyrus S, Wiltbank T, Schammel C, Alexander S. HTLV-I EIA false-negative rate: failure to detect HTLV-I and HTLV-II-positive donations. Transfusion 1992;32:S219 p. 57S (abstr). 27. Wilson C, Cyrus S, Schammel C, Hjelle B. False-negative screening tests for HTLV-I and -II in contemporary U.S. blood donors. (abstr ACP/ASIM New Mexico Scientific Meeting December 1992). 28. Hjelle B, Zhu SW, Ijichi S, Hall WW. Endemic HTLV-II infection in Southwestern U.S. Indians is associated with two prototype strains of virus. Blood 1992;80(Suppl 1):329a (abstr 1307). 29. Hjelle B, Torrez-Martinez N, Jenison S. Antibodies to pol and tax gene products in HTLV-II infection: an immunodominant region in the C-terminus of tax2. Transfusion 1993;68S (abstr S261). 30. Stramer SL, Dillender MJ, Coleman CL, Fang CT, Tegtmeier GE, Cyrus S, Hjelle B. Comparison of HTLV-I antigen containing test kits for the detection of antibodies to HTLV-I and HTLV-II. Transfusion 1993;39S (abstr S147). 31. Hjelle B, Spiropoulou CF, Morzunov S, Nichol ST. Acute infection by Four Corners hantavirus is associated with viral RNA sequences in peripheral blood mononuclear cells and plasma. Blood 1993;(abstr #742 p. 189a). 32. Jenison S, Hjelle B, Yamada T, Torrez-Martinez N, Anderson B. Development of a recombinant immunoblot assay for the rapid diagnosis of Four Corners hantavirus (FCV). Late Breakers session 33rd Interscience Conference on Antimicrobial Agents and Chemotherapy Oct. 17-20 1993 New Orleans Louisiana (abstr #20) 33. Nerurkar VR, Song K-J, Nagle JW, Hjelle B, Jenison S, Yanagihara R. Genetic evidence for a hantavirus-related enzootic in deer mice (Peromyscus maniculatus) captured in Mono County California a decade before the recognition of hantavirus pulmonary syndrome. (abstr) Amer Soc Virol 13th Ann Mtg July 9-13 1994 Virology 1994;204:563-8.

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34. Hjelle B, Yates T, Jenison S, Parmenter R, Foxx T, Biggs J, Bennett K, Webb J, Sarisky J, Ascher M, Yanagihara R. Molecular variation of New World hantaviruses. 34th Interscience Symposium on Antimicrobial Agents and Chemotherapy. (abstr) Oct 4-7 1994 symposium 67 p. 285. 35. Jenison S, Hjelle B, Koster F, Foucar K. Clinical and laboratory diagnosis of hantavirus pulmonary syndrome. 34th Interscience Symposium on Antimicrobial Agents and Chemotherapy. (abstr) Oct 4-7 1994 symposium 67 p. 285. 36. Hjelle B, Torrez-Martinez N, Song W, Anderson B, Gannon WL, Yates T. Genetic identification of a novel hantavirus in a harvest mouse (Reithrodontomys mexicanus) in Costa Rica. Keystone Symposium on Molecular Aspects of Viral Immunity Jan 16-23 1995 J Cell Biochem 1995 suppl 19A (abstr J2 344 p. 319). 37. Anderson B, Yates T, Torrez-Martinez N, Song W, Hjelle B. Widespread enzootic of a novel hantavirus of the harvest mouse in North America. Keystone Symposium on Molecular Aspects of Viral Immunity Jan 16-23 1995 J Cell Biochem 1995 suppl 19A (abstr J2343 p. 319). 38. Hjelle B. New World hantaviruses and hantavirus disease: ecology and host relationships. Annual meeting of the West Central Mosquito and Vector Control Association Santa Fe New Mexico February 15-16 1995. 39. Chomel BB, Jay M, Reilly K, Rollin PE, Ksiazek TG ,Hjelle B, Ascher M. Epidemiology of hantavirus pulmonary syndrome in the United States 1993-1994 and serosurveilllance of rodent infection in California. Preliminary results. Presented at International Congress on Quality Veterinary Services for the 21st Century Nov 15-17 1994 Kuala Lumpur Malaysia. 40. Song J-W, Baek LJ, Gavrilovskaya I, Mackow ER, Hjelle B, Yanagihara R. Sequence analysis of the complete S genomic segment of a hantavirus isolated from the white-footed mouse (Peromyscus leucopus). Amer Soc Virol 14th Ann Mtg July 8-12 1995 Austin Texas (abstr P8-6 p. 124). 41. Hjelle B, Song W, Torrez-Martinez N, Mackow E, Ascher M, Webb J, Yanagihara R, Yates T. Identification of 5 new American hantaviruses. Amer Soc Virol 14th Ann Mtg July 8-12 1995 Austin Texas (abstr P8-4 p. 124). 42. Mackow ER, Lee SW, Luft B, Song J-W, Yanagihara R, Hjelle B, Gavrilovskaya I. Identification and molecular analysis of NY hantavirus strain M segment. Amer Soc Virol 14th Ann Mtg July 8-12 1995 Austin Texas (abstr W19-2 p. 138). 43. Song J-W, Baek LJ, Gavrilovskaya IN, Mackow ER, Hjelle B, Yanagihara R. Sequence analysis of the complete S genomic segment of a newly identified hantavirus harbored by the

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white-footed mouse (Peromyscus leucopus). 3rd International Conference on HFRS and Hantaviruses May 31-June 3 1995 Helsinki Finland (abstr 105). 44. Hjelle B, Torrez-Martinez N, Song W, Song J-W, Yanagihara R, Lee S-W, Gavrilovskaya I, Mackow ER. Genetic characterization of the M genome of New York-1 hantavirus: molecular linkage of hantavirus pulmonary syndrome to the white-footed mouse Peromyscus leucopus. 3rd International Conference on HFRS and Hantaviruses May 31-June 3 1995 Helsinki Finland (abstr 28). 45. Song W, Quintana M, Torrez-Martinez N, Ascher M, Jay M, Hjelle B. High genetic complexity of hantavirus radiation of New World microtine voles (Rodentia:Microtus). 3rd International Conference on HFRS and Hantaviruses May 31-June 3 1995 Helsinki Finland (abstr session 1 oral). 46. Hjelle B, Torrez-Martinez N, Anderson B, Song W, Gannon W, Yates T. Evidence for a widespread and longstanding hantavirus enzootic of American harvest mice with identification of a unique genotype (Rio Segundo virus) in Costa Rica. 3rd International Conference on HFRS and Hantaviruses May 31-June 3 1995 Helsinki Finland (abstr 78). 47. Hjelle B, Torrez-Martinez N, Song W, Jay M, Ascher M, Sarisky J, Enscore R, Brown T, Reynolds P. Molecular epidemiology investigations of Four Corners virus (FC)-associated hantavirus pulmonary syndrome. 3rd International Conference on HFRS and Hantaviruses May 31-June 3 1995 Helsinki Finland (abstr 79). 48. Hjelle B, Song W, Torrez-Martinez N. Genetic and serologic features of El Moro Canyon virus (ELMC) a hantavirus associated with the western harvest mouse Reithrodontomys megalotis. 3rd International Conference on HFRS and Hantaviruses May 31-June 3 1995 Helsinki Finland (abstr 29 session 3 oral). 49. Banerjee SN, Artsob H, Dick D, Werker D, Hjelle B, Stephen C ,Middleton PJ. Hantavirus studies in British Columbia Canada. 50th Ann Mtg of NW Intl Conf on Diseases of Nature Communicable to Man Calgary Canada 1995 (abstr). 50. Hjelle B, Goade D, Torrez-Martinez N, Herndier B, Bell R, Jenison S. Cloning of the majority of the major capsid protein (MCP) gene of Kaposi’s sarcoma-associated herpesvirus (KSHV). Transfusion 1995;35: S257 p. 65S (abstr). 51. Appenzeller O, Snyder RD, Kornfeld M, Hjelle B. Neuropathy in Navajo children: molecular aspects. Meeting of the Peripheral Nerve Society Antalya Turkey October 6-9 1995 (abstr). 52. Hjelle B, Salka C, Jenison S, Morris C, Koster F, Pichuantes S, Quan S, Dinello R, Polito A. RIBATM hantavirus strip immunoblot assay (H-SIA) for rapid diagnosis of hantavirus

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pulmonary syndrome (HPS). abstr 158-V30 96th Ann Mtg of the Amer Soc for Microbiology New Orleans May 19-23 1996 (abstr). 53. Hjelle B, Torrez-Martinez N, Koster F, Jay M, Ascher M, Sarisky J, Enscore R, Brown T, Reynolds P. Epidemiologic linkage of rodent and human viral sequences in cases of hantavirus pulmonary syndrome (HPS). abstr 105-C127 96th Ann Mtg of the Amer Soc for Microbiology New Orleans May 19-23 1996 (abstr). 54. Goade DE, Mertz GJ, O’Rourke A, Hjelle B. Sequential development of specific herpes simplex virus type 2 (HSV-2) antibodies to HSV surface glycoproteins following primary genital infection. Gen Clin Res Centers Conf March 6-9 1996 (abstr). 55. Rawlings JA, Neill SU, Moore GM, Hicks BN, Torrez-Martinez N, Goade D, Hjelle B. Coexistence of four hantaviruses in Texas USA.Abstr W22-9 (Bunyavirus oral workshop) 15th Ann Mtg of the Amer Soc for Virology London Ontario July 13-17 1996 (abstr). 56. Hjelle B, Salazar J, Torrez-Martinez N, Bharadwaj M, Koster F, Yates T. New sigmodontine rodent-borne hantavirus from Bolivia. Abstr W22-8 (Bunyavirus oral workshop) 15th Ann Mtg of the Amer Soc for Virology London Ontario July 13-17 1996 (abstr). 57. Clement J, Mc Kenna P, Heyman P, Colson P, Hjelle B. Serum lipid perturbations as predictors of clinical severity in European and American hantavirus infections. 7th Intl Conf of Infect Dis Hong Kong June 10-13 1996 (abstr). 58. Green W, Feddersen R, Behr M, Hjelle B. Immunodetection of hantavirus in tissues of naturally infected humans and deer mice. Ann Mtg of ACVP/ASVCP Seattle Washington December 2-6 1996 (abstr). 59. Irwin WE, Harrison FJ, Walker TW, Reichenbacker RR, Hale LD, Torrez-Martinez N, Hjelle B. Surveillance for hantavirus antibody in rodents on military installations in the western United States. 45th Ann Mtg of the Amer Soc Trop Med Hyg Baltimore December 1-5 1996 (abstr 36 oral). 60. Hjelle B, Jenison S, Torrez-Martinez N, Artsob H, Pichuantes S, Quan S, DiNello R, Polito S. Strip immunoblot assay (SIA) for rapid diagnosis of hantavirus pulmonary syndrome. 45th Ann Mtg of the Amer Soc Trop Med Hyg Baltimore December 1-5 1996 (abstr 41 oral). 61. Goade D, Torrez-Martinez N, McPherson T, Miller M, Bennett J, Harlan H, Song J-W, Yanagihara R, Hjelle B. Monongahela hantavirus (MONV) is widespread in eastern US and causes hantavirus pulmonary syndrome. 45th Ann Mtg of the Amer Soc Trop Med Hyg Baltimore December 1-5 1996 (abstr 31 oral).

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62. Torrez-Martinez N, Tabony L, Neill SU, Moore G, Hicks B, Hjelle B. Enzootic of Muleshoe hantavirus (MULEV) in cotton rats (Sigmodon hispidus) in Texas. 45th Ann Mtg of the Amer Soc Trop Med Hyg Baltimore December 1-5 1996 (abstr 34 oral). 63. Moore G, Torrez-Martinez N, Goade D, Tabony L, Neill S, Hicks B, Rawlings J, Hjelle B. Direct evidence implicating the rice rat Oryzomys palustris as carrier of hantavirus pulmonary syndrome in Texas. 45th Ann Mtg of the Amer Soc Trop Med Hyg Baltimore December 1-5 1996 (abstr 32 oral). 64. Gavrilovskaya I, Hjelle B, Ceradini D, Brill R, Springer K, Fay M, Mackow E. Evaluation of Neutralizing Antibody Responses to NY-1 Hantavirus. 45th Ann Mtg of the Amer Soc Trop Med Hyg Baltimore December 1-5 1996 (abstr 37 oral). 65. Clement J, Heyman P, Colson P, Hjelle B. Serum lipid perturbations as predictors of clinical severity in European and American hantavirus infections. 1st Intl Conf on Emerging Zoonoses Jerusalem November 24-28 1996. (abstr) 66. Jay M, Chomel B, Graham T, Madon M, Reilly K, Sesline D, Hjelle B, Enge B, Rollin P, Ksiazek T, Ascher M. Epidemiology of hantavirus pulmonary syndrome in California and serosurveillance of rodent infection. 1st Intl Conf on Emerging Zoonoses Jerusalem November 24-28 1996. (abstr) 67. Barclay C, Lazaro M, Simpson SQ, Hjelle B. Clinical and epidemiologic notes on a 1996 hantavirus pulmonary syndrome outbreak in Patagonia. 16th Ann Mtg of the Amer Soc for Virology Bozeman Montana July 19-23 1997 (abstr W32-3 oral p. 152). 68. Mackow E, Springer K, Fay M, LaMonica R, Bharadwaj M, Hjelle B, Schmaljohn C, Gavrilovskaya I. Eight residues of the hantavirus nucleocapsid protein confer both crossreactive and SN strain-specific MAB recognition. 16th Ann Mtg of the Amer Soc for Virology Bozeman Montana July 19-23 1997 (abstr W32-12 oral p. 153). 69. Goade DE, Koster FT, Hjelle B, Mertz G. A search for residual disease in survivors of hantavirus infections. Gen Clin Res Cntr National Conference March 1997 Washington DC (abstr). 70. Bennett SG, Webb JP, Hjelle B, Fogarty CL, Miladin SB, Challett GL. Sin Nombre virus and El Moro Canyon virus (Bunyaviridae: Hantavirus) in rodents (Muridae: Sigmodontinae) from Orange County California. Proc Mosq and Vector Control Assoc of California 1996; 64: 73-9 (abstr).

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71. Lindsey R, Kennon C, Merker L, Hjelle B. Detection of bacterial DNA in blood samples by heminested PCR. 37th Interscience Symposium on Antimicrobial Agents and Chemotherapy. (abstr) Sept 28-Oct 1 1997 Toronto Ontario (064-D poster) 72. Ferrer JF, Jonsson C, Esteban E, Basombrio MA, Peralta-Ramos M, Segovia A, Hjelle B. High prevalence of hantavirus antibodies in Indian communities of northeastern Argentina and Central Paraguay. 46th Ann Mtg of the Amer Soc Trop Med Hyg Orlando December 7-11 1997 (abstr 125 oral). 73. Feddersen RM, Hjelle B, Bharadwaj M, Barclay C, Samengo L. Microscopic pathologic findings and tissue distribution of viral antigen in hantavirus pulmonary syndrome due to Andes virus. 46th Ann Mtg of the Amer Soc Trop Med Hyg Orlando December 7-11 1997 (abstr 126 oral). 74. Simpson SQ, Koster FT, Hjelle ,B Montoya J, Goade D. Serum cytokine and cytokine receptor levels correlate with severity of North American hantavirus pulmonary syndrome. 46th Ann Mtg of the Amer Soc Trop Med Hyg Orlando December 7-11 1997 (abstr 128 oral). 75. Koster FT, Hjelle B, Goade D, McCabe M, Iralu J, Crook L, Foucar K, Simpson S, Levy H. Recognition of the prodrome phase of hantavirus pulmonary syndrome and relationship of early shock to mortality. 46th Ann Mtg of the Amer Soc Trop Med Hyg Orlando December 7-11 1997 (abstr 129 oral). 76. Cullman LC, Hjelle B, Tarleton C, Rood M. The detection of Seoul virus antibody in urban and suburban rats in Los Angeles Co. California. Fourth Intl Conference on HFRS and Hantaviruses. Atlanta GA Mar 5-7 1998 (abstr poster). 77. Mansilla C, Tapia M, Nolte K, Barclay C, Samengo L, Feddersen R, Hjelle B. Pathological findings and distribution of viral antigens in tissues of patients with fatal Andes hantavirus infection. Fourth Intl Conference on HFRS and Hantaviruses. Atlanta GA Mar 5-7 1998 (abstr oral). 78. Bharadwaj M, Vial ,P Botten J, Cerda M G,. Mertz G, Hjelle B. Andes virus-associated HPS in Chile: presence of viral RNA in tracheal aspirate suggests potential route for interpersonal transmission. Fourth Intl Conference on HFRS and Hantaviruses. Atlanta GA Mar 5-7 1998 (abstr poster). 79. Botten J, Calisher C, Doyle T, Tanda D, Miller L, Irland C, Bryan RT, Hjelle B. Combined genetic and epidemiologic investigations to distinguish the site of exposure to Sin Nombre virus and th HPS incubation period. Fourth Intl Conference on HFRS and Hantaviruses. Atlanta GA Mar 5-7 1998 (abstr poster).

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80. Rawlings J, Bharadwaj M, Rodriguez-Moran P, Hicks B, White M, Moore G, Hunt ,P Hjelle B. Update on hantaviruses and HPS in Texas. Fourth Intl Conference on HFRS and Hantaviruses. Atlanta GA Mar 5-7 1998 (abstr poster). 81. Botten J, Nofchissey R, Rodriquez-Moran P, Ahern H, Yates T, Goade D, Hjelle B. Facility for studies of laboratory and field transmission of Sin Nombre virus in deer mice. Fourth Intl Conference on HFRS and Hantaviruses. Atlanta GA Mar 5-7 1998 (abstr poster). 82. Rodriguez-Moran P, Torrez-Martinez N, Bharadwaj M, Goade D, Rawlings J, Hicks B, Nix B, Hjelle B. Bayou hantavirus pulmonary syndrome in Texas: identification of the rice rat Oryzomys palustris as the rodent reservoir host. Fourth Intl Conference on HFRS and Hantaviruses. Atlanta GA Mar 5-7 1998 (abstr poster). 83. Ferrer JF, Jonsson C, Estaban N, Galligan D, Basombrio MA, Peralta-Ramos M, Bharadwaj M, Torrez-Martinez N, Segovia A, Hjelle B. Epidemiological features of SNV-related hantavirus infection in high prevalence Gran Chaco Indian populations. Fourth Intl Conference on HFRS and Hantaviruses. Atlanta GA Mar 5-7 1998 (abstr oral). 84. Mackow E, LaMonica R, Fay M, Springer K, Hjelle B, Bharadwaj M, Schmaljohn C, Shaw R, Gavrilovskaya I. Site-specific mutagenesis of the NY-1 N protein defines residues required for strain-specific and cross-reactive Mab recognition of HPS-associated hantaviruses. Fourth Intl Conference on HFRS and Hantaviruses. Atlanta GA Mar 5-7 1998 (abstr poster). 85. Gavrilovskaya I, LaMonica R, Fay ME, Hjelle B, Schmaljohn C ,Mackow ER. The NY-1 virus is a serotypically distinct hantavirus associated with hantavirus pulmonary syndrome. Fourth Intl Conference on HFRS and Hantaviruses. Atlanta GA Mar 5-7 1998 (abstr poster). 86. Joachini L, Thompson M, Almiron M, Russomando G, Iwasaki E, Torrez-Martinez N, Hjelle B, Von Bredow, Rojas C, De Arias A, Jonsson CB. Prevalence of hantavirus antibodies in select populations of eastern and western Paraguay. Fourth Intl Conference on HFRS and Hantaviruses. Atlanta GA Mar 5-7 1998 (abstr oral). 87. Irwin W, Goade DE, Richardson JH, Nofchissey R, Thomas JR, Hjelle B. Feasibility of on-site western blot antibody testing during wild rodent surveys. Fourth Intl Conference on HFRS and Hantaviruses. Atlanta GA Mar 5-7 1998 (abstr poster). 88. Koster FT, Williams T, Griffith B, Goade D, Hjelle B, and the Emerging Viruses Research Group. Genetic susceptibility to hantavirus pulmonary syndrome due to Sin Nombre virus. Fourth Intl Conference on HFRS and Hantaviruses. Atlanta GA Mar 5-7 1998 (abstr poster). 89. Botten JW, Kirkendoll-Ahern H, Yates T, Ricci R, Bharadwaj M, Wortman IA, Hjelle B. Development of an animal model for Sin Nombre hantavirus infection using a novel outdoor

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biocontainment facility. American Soc for Virology 18th Ann Mtg July 10-14 1999 Amherst MA (abstr oral). 90. Kirkendoll-Ahern H, Botten JW, Kusewitt D, Feddersen R, Wortman IA, Hjelle B. Kinetics and tissue distribution of acute Sin Nombre virus infection in the deer mouse. American Soc for Virology 18th Ann Mtg July 10-14 1999 Amherst MA (abstr oral). 91. Bharadwaj M, Lyons CR, Wortman IA, Hjelle B. Intramuscular inoculation of Sin Nombre hantavirus cDNAs induces cellular and humoral immune responses in BALB/c mice. American Soc for Virology 18th ann mtg July 10-14 1999 Amherst MA (abstr oral). 92. Rodriguez-Moran P, Wortman IA, Hjelle B. Increased caseload of hantavirus cardiopulmonary syndrome (HCPS) after the 1997-98 El Niño event. American Soc for Virology 18th ann mtg July 10-14 1999 Amherst MA (abstr oral). 93. Botten J, Kirkendoll-Ahern H, Rodriguez-Moran P, Kusewitt D, Feddersen R, Mirowsky K, Nofchissey R, Goade D, Hjelle B. Animal model for Sin Nombre hantavirus (SNV) infection in deer mice: early viral invasion of heart and brown fat. 48th Ann Mtg of the Amer Soc Trop Med Hyg Washington November 28- December 2 1999 (abstr 402 oral). 94. Rodriguez-Moran P, Hjelle B. Hantavirus outbreak in the Four Corners states subsequent to El Niño event of 1997-98. 48th Ann Mtg of the Amer Soc Trop Med Hyg Washington November 28- December 2 1999 (abstr 407 oral). 95. Goade DE, Nofchissey RA, Hjelle B, Hanfelt JJ, Koster F. Fatigue proteinuria and pulmonary function changes in survivors of HCPS. 48th Ann Mtg of the Amer Soc Trop Med Hyg Washington November 28- December 2 1999 (abstr 408 oral). 96. Olson D, Williams T, Hjelle B, Goade D, Mertz G, Koster F. An association between severe hantavirus cardiopulmonary syndrome and HLA-B*35: preliminary data. 48th Ann Mtg of the Amer Soc Trop Med Hyg Washington November 28- December 2 1999 (abstr 409 oral).

97. Nofchissey RA, Goade DE, Hjelle B. The presence of IgM IgG and IgA serum antibodies in acute and convalescent patients with hantavirus pulmonary syndrome. 48th Ann Mtg of the Amer Soc Trop Med Hyg Washington November 28- December 2 1999 (abstr 597 poster). 98. Botten J, Mirowsky K, Kusewitt D, Feddersen R, Ricci R, Hjelle B. Kinetics and tissue distribution of experimental Sin Nombre hantavirus infection in the deer mouse model. Keystone Symposium on Genetics Pathogenesis and Ecology of Emerging Viral Diseases (J1) Taos NM Jan 24-30 2000 (abstr poster/oral).

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99. Bharadwaj M, Nofchissey R, Goade D, Koster F, Hjelle B. Humoral immune responses in the hantavirus cardiopulmonary syndrome. . Keystone Symposium on Genetics Pathogenesis and Ecology of Emerging Viral Diseases (J1) Taos NM Jan 24-30 2000 (abstr poster/oral). 100. Clement J, Chu Y-K, Hjelle B, Vervoort T, Avsic-Zupanc T, Colson P, Van Ranst M. Hantaviruses: emerging yet ubiquitous. Pathology 2000 Conf Birmingham U.K. 15-17 May 2000 (abstr) 101. Bharadwaj M, Mirowsky K, Botten J, Lyons CR, Yee J, Nofchissey R, Hjelle B. Intramuscular inoculation of Sin Nombre hantavirus cDNAs protects deer mice from challenge with Sin Nombre virus. American Society for Virology 19th Ann Mtg Fort Collins CO July 8-13 2000 (abstr oral). 102. Ijaz MK, Suchmann DB, Hjelle B. Hantaviruses: evaluation of virucidal efficacy of some selected disinfectants against Prospect Hill virus. International Conference on Emerging Infectious Diseases 2000 July 16-19 Atlanta GA (abstr poster). 103. Lanzi RA, Goade DE, Hjelle B, Koster F. Hantavirus pulmonary syndrome survivors have reduced health related quality of life. J Invest Med 2000; 48(1/SS): 402-402 104. Botten JW, Yee JA, Mirowsky K, Bharadwaj M, Hjelle B. TaqMan quantitative reverse transcriptase-PCR studies of Sin Nombre hantavirus in the deer mouse model. 49th Ann Mtg of the Amer Soc Trop Med Hyg Houston October 29- November 2 2000 (abstr 228 oral). 105. Bharadwaj M, Mirowsky K, Botten J, Hjelle B. Genetic vaccines that protect against Sin Nombre virus challenge in the deer mouse (Peromyscus maniculatus) model. 49th Ann Mtg of the Amer Soc Trop Med Hyg Houston October 29- November 2 2000 (abstr 229 oral). 106. Markey MA, Hjelle BL, Becher MW. Immunocytochemical localization of hantavirus in the CNS of patients with hantavirus cardiopulmonary syndrome. 77th Ann Mtg Amer Assn of Neuropathologists Chicago June 21-24 2001. 107. Welsh BN, Nofchissey RA, Hjelle B, Goade DE. Humoral immune responses of convalescent patients with hantavirus pulmonary syndrome (HPS). Fifth Intl Conference of HFRS HPS and hantaviruses Veyrier-du-Lac France June 14-16 2001. (abstr) 108. Galeno H, Acevedo W, Mora J, Villagra E, Fernandez J, Mertz G, Hjelle B. Neutralizing antibody titers in Chilean patients with HCPS due to Andes hantavirus- preliminary findings. Fifth Intl Conference of HFRS HPS and hantaviruses Veyrier-du-Lac France June 14-16 2001. (abstr)

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109. Nofchissey RA, Erwin W, Hanfelt M, Quintana M, Hjelle B. On-Site Testing of IgG Antibody Prevalence to Sin Nombre Virus in Idaho Utah and New Mexico USA. Fifth Intl Conference of HFRS HPS and hantaviruses Veyrier-du-Lac France June 14-16 2001. (abstr) 110. Goade DE, Nofchissey RA, Lanzi R, Roldan C, James D, Garlin A, Koster FT, Hanfelt J, Angeli E, Stearns C, Ketai L, Hjelle B. Long term fatigue proteinuria and pulmonary sequelae following HPS. Fifth Intl Conference of HFRS HPS and hantaviruses Veyrier-du-Lac France June 14-16 2001. (abstr oral) 111. Goade DE, Nofchissey R, Perea J, Hanfelt J, Hjelle B, Leach JK. SNV hantavirus associated myocardial hypokinesis in a rat model. Fifth Intl Conference of HFRS HPS and hantaviruses Veyrier-du-Lac France June 14-16 2001. (abstr) 112. Navarrete M, Mancilla R, Saldias F, Zaror L, Ferres M, Hjelle B Vial PA. Hantavirus case clusters in Valdivia Chile support both high-risk exposure sites and probable person-to-person transmission of Andes hantavirus. Fifth Intl Conference of HFRS HPS and hantaviruses Veyrier-du-Lac France June 14-16 2001. (abstr) 113. Gracia F, Pascale J, Armien B, Benalcazar E, Pinilla E, Pineda J, Rivera F, EQuiroz E, Koster F, Hjelle B, Feddersen R. Clinical and histologic features of Choclo virus infection in Panama. . Fifth Intl Conference of HFRS HPS and hantaviruses Veyrier-du-Lac France June 14-16 2001. (abstr) 114. Gracia F, Pascale J, Armien B, Delgado M, Yee J, Xiao R, Ponce L, Quiroz E, Bayard V, Castillo Z, Guerrero G, Mosca I, Munoz C, Koster F, Hjelle B. High seroprevalence to hantaviruses in the Azuero peninsula of Panama. Fifth Intl Conference of HFRS HPS and hantaviruses Veyrier-du-Lac France June 14-16 2001. (abstr) 115. Gracia F, Armien B, Pascale JM, Hjelle B, Koster F. Post hantavirus syndrome following severe HCPS due to Choclo virus in Panama. Fifth Intl Conference of HFRS HPS and hantaviruses Veyrier-du-Lac France June 14-16 2001. (abstr) 116. Xiao R, Ponce L, Nofchissey R, Botten J, Ye C, Goade D, Moseley P, Hjelle B. Reactivation of Sin Nombre virus in cultured cells by heat stress. Fifth Intl Conference of HFRS HPS and hantaviruses Veyrier-du-Lac France June 14-16 2001. (abstr) 117. Botten J, Mirowsky K, Hjelle B. Viral shedding and transmission in experimental Sin Nombre hantavirus infection in the deer mouse (Peromyscus maniculatus). Fifth Intl Conference of HFRS HPS and hantaviruses Veyrier-du-Lac France June 14-16 2001. (abstr, oral) 118. Botten J, Mirowsky K, Yee J, Kusewitt D, Feddersen RM, Hjelle B. Persistent Sin Nombre virus infection in the deer mouse (Peromyscus maniculatus) model: restricted tissue distribution

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and viral reactivation. Fifth Intl Conference of HFRS HPS and hantaviruses Veyrier-du-Lac France June 14-16 2001. (abstr oral) 119. Gracia F, Pascale J, Armien B, Benalcazar E, Pinilla ,E Pineda J, Rivera F, Quiroz E, Delgado M, Yee J, Xiao R, Ponce L, Bayard V, Castillo Z, Guerrero G, Mosca I, Munoz C, Feddersen R, Koster F, Hjelle B. High seroprevalence to hantaviruses and milder clinical syndrome associated with Choclo virus in the Azuero peninsula of Panama. Ann Mtg for the Intl Center Trop Dis Res Washington May 7 2001. (abstr) 120. Vial PA, Mertz GJ, Galeno H, Aguilera X, Ferrés M, Hjelle B, Palma E, Yates T, Castillo C, Tapia M, Mora J, Noriega M, Sotomayor V, Belmar E, Villagra E, Koster F, Marquet P, Medina RP, Godoy P, Acevedo W, Täger M, Pavletic C, Belmar R, Johnson K. Hantavirus ecology and disease in Chile. Ann Mtg for the Intl Center Trop Dis Res Washington May 7 2001. (abstr) 121. Botten J, Mirowsky K, Yee J, Kusewitt D, Fedderson RM, Hjelle B. Persistent Sin Nombre virus infection in the deer mouse (Peromyscus maniculatus) model: restricted tissue distribution and viral reactivation. 50th Ann Mtg of the Amer Soc Trop Med Hyg Atlanta November 11- 15 2001 (abstr). 122. Timlin JA, Martin LE, Alam MK, Haaland DM, Garrison KA, Lyons CR, Hjelle B. Infrared ATR: A Probe for Cellular Activation. SPIE Conf on Vibrational Spectroscopy Sensors. Boston MA Nov 1-2 2001 (abstr conf # 4577). 123. Bharadwaj M, Ye C, Mirowsky K, Botten J, Masten B, Lyons R, Hjelle H. Rapid vaccine paradigm for defense against agents of bioterrorism: first proof of principle. BTR 2002: Unified Science & Technology for Reducing Biological Threats & Countering Terrorism. Albuquerque Mar 14-15 2002 (abstr). 124. Ye C, Goade D, Nofchissey R, Bharadwaj M, Prescott J, Crookston K, Hjelle B. Promise of passive immunotherapy for hantavirus cardiopulmonary syndrome (HCPS). 21st Ann Mtg Amer Soc Virol Lexington KY July 20-24 2002 (abstr P226-6 poster). 125. Xiao R, Ponce L, Nofchissey R, Botten J, Ye C, Goade D, Moseley P, Hjelle B. Reactivation of Sin Nombre (SN) virus in cultured cells by heat stress. 21st Ann Mtg Amer Soc Virol Lexington KY July 20-24 2002 (abstr P22-7 poster). 126. Medina R, Villagra E, Fernendez J, Navarrete M, Galeno H, Palma E, Vial P, Hjelle B. Andes virus is little-diversified and causes a widespread enzootic in a wide variety of rodent species in Chile. 21st Ann Mtg Amer Soc Virol Lexington KY July 20-24 2002 (abstr P22-2, poster).

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127. Botten J, Mirowsky K-M, Ye C, Gottlieb K, Saavedra M, Ponce L, Hjelle B. Viral shedding and transmission in experimental Sin Nombre hantavirus infection in the deer mouse (Peromyscus maniculatus). 21st Ann Mtg Amer Soc Virol Lexington KY July 20-24 2002 (abstr P22-5, poster). 128. Botten J, Mirowsky K-M, Kusewitt D, Ye C, Hjelle B. Persistent Sin Nombre virus infection in the deer mouse (Peromyscus maniculatus) model. 21st Ann Mtg Amer Soc Virol Lexington KY July 20-24 2002 (abstr oral W34-1). 129. Goade D, Nofchissey R, Lanzi R, Roldan C, James D, Hanfelt J, Hjelle B, Koster F. A longitudinal prospective study of survivors of HPS. 21st Ann Mtg Amer Soc Virol Lexington KY July 20-24 2002 (abstr oral W28-3). 130. Rangel M, Carruthers T, Prescott J, Schountz T, Hjelle B. Toward development of reagents for immunologic study of deer mice. 22nd Ann Mtg Amer Soc Virol Davis CA July 12-16 2003 (abstr, oral W45-9). 131. Alexander JL, McDonald K, Wilson B, Woods S, Garner W, Ward T, Berger J, Prescott J, Hjelle B. Multiple hantavirus pulmonary syndrome cases from one exposure site in Texas. The 53rd Ann SW Conf Dis Nat Trans Man, Amarillo, TX June 25-27, 2003, (abstr, oral). 132. B Klempa B, HA Schmidt HA, R Ulrich R, H Meisel H, M Labuda M, B Hjelle B, DH Krüger DH. Sympatric existence and genetic interaction of hantavirus lineages carried by different host species. 12th Intl Conf on Neg Strand Viruses, Pisa, Italy, June 14-19 2003 (abstr, poster). 133. Yang SQ, Xiao R, Koster F, Hjelle B. Quantitative analysis of Sin Nombre hantavirus RNA in the peripheral blood mononuclear cells, plasma, urine and tracheal aspirates in patients with hantavirus cardiopulmonary syndrome. 12th Intl Conf on Neg Strand Viruses, Pisa, Italy, June 14-19 2003 (abstr, poster). 134. Aldunate R., Vial P., Palma E., Ferres M., and Hjelle B. Quantitative distribution of Andes hantavirus RNA in the tissues of reservoir host rodents. 12th Intl Conf on Neg Strand Viruses, Pisa, Italy, June 14-19 2003 (abstr, poster). 135. Medina R, Villagra E, Fernendez J, Navarrete M, Galeno H, Palma E, Vial P, Hjelle B. Andes virus is little-diversified and causes a widespread enzootic in a wide variety of rodent species in Chile. 12th Intl Conf on Neg Strand Viruses, Pisa, Italy, June 14-19 2003 (abstr, poster).

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136. Vial P, Ferrés M, Belmar E, Castillo C, Tapia M, Donoso S, Ortega C, Noriega M, Navarro E, Aldunate R, Ferrer P, Godoy P, Yañez L, Hjelle B, Mertz G. Hantavirus in Chile: incubation period, clinical characteristics and viral load in Chilean HCPS patients. 12th NIAID International Centers for Trop Dis Res Network, Bethesda, MD May 13-15, 2003 (abstr, oral). 137. Ferrés M, Vial P, Yañez L, Belmar E, Castillo C, Navarrete M, Mansilla R, Tager M, Godoy P, Aldunate R, Ferrer P, Galeno H, Palma E, Hjelle B, Mertz G. Prospective natural history study of household contacts of persons with acute hantavirus cardiopulmonary syndrome in Chile. 12th NIAID International Centers for Trop Dis Res Network, Bethesda, MD May 13-15, 2003 (abstr, oral). 138. Hjelle B, Aldunate R, Vial P, Xiao R, Botten J, Ferrer P, Palma E. Hantavirus pathogenesis in mouse and man. 12th NIAID International Centers for Trop Dis Res Network, Bethesda, MD May 13-15, 2003 (abstr, oral). 139. Armien B, Pascale JM, Gracia F, Bayard V, Armien A, Muñoz C, Quiroz E, Zaldívar Y, Guerrero G, Mosca I, Castillo Z, Suzan G, Salazar-Bravo J, Yates T, Hjelle B, Mertz G, Koster F. Epidemiology of hantavirus infections in Panama. 4th Ann Mtg of Chilean-American ICIDR “Hantavirus Ecology and Disease in Chile” Coyhaique, Chile Apr 2-4, 2003 (abstr, oral). 140. Pascale JM, Armien B, Salazar-Bravo J, Zaldívar, Armien A, Gracia F, Quiroz E, Bayard V, Castillo Z, Muñoz C, Suzan G, Yates T, Hjelle B, Koster F, Mertz G. Characterization of New Hantaviruses in Panama. 4th Ann Mtg of Chilean-American ICIDR “Hantavirus Ecology and Disease in Chile” Coyhaique, Chile Apr 2-4, 2003 (abstr, oral). 141. Mertz GJ, Miedzinski L, Goade D, Pavia A, Hjelle B, Hansbarger CO, Levy H, Koster FT, Lindemulder A, Carpenter M, Zhang S, Riser L, Fernandez H, Whitley R & the collab antivir stud gp. Placebo-controlled, double blind trial of intravenous ribavirin for hantavirus cardiopulmonary syndrome in the US and Canada. 43rd Ann Mtg of Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), Chicago, 14-17 Sept 2003 (abstr V-482, oral). 142. Hjelle B, Koster F, Botten J, Ye C, Rangel M, Schountz T. Hantaviruses in the southwest: pathogenesis and epidemiology in man and mouse. 58th Intl Conf on Dis Nature Comm to Man, Flagstaff, Aug 4-6, 2003 (abstr, oral). 143. Rangel M, Carruthers T, Prescott J, Schountz T, Hjelle B. Development of reagents for immunologic study of deer mice. 58th Intl Conf on Dis Nature Comm to Man, Flagstaff, Aug 4-6, 2003 (abstr, poster).

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144. Medina RA, Mirowsky K, Hamel R, Hjelle, B. Ribavirin, but not anti-β3 integrin antibody, prevents infection by Sin Nombre virus in the deer mouse model. Keystone Symp Bioterrorism Emerg Infect Dis: Antimicrobials, Therapeutics and Immune-Modulators. 6-11 Jan 2004, Keystone, CO (abstr, poster 104). 145. Ferrés M, Vial P, Yañez L, Belmar E, Castillo C, Navarrete M, Sanhueza L, Godoy P, Aldunate R, Ferrer P, Medina R, Araya N, Galeno H, Hjelle B, Mertz G. Prospective natural history study of household contacts of persons with acute hantavirus cardiopulmonary syndrome (HCPS) in Chile. 52nd Ann Mtg of the Amer Soc Trop Med Hyg Philadelphia, 3-7 December 2003 (late breaker abstr). 146. Schmidt J, Meisel H, Hjelle B, Capria SG, Vial PC, Padula P, Krüger DH, Ulrich R. Development and evaluation of serological assays for the detection of human hantavirus infections imported to Europe. Gesellschaft für Virologie mtg, Tübingen, 2004 (abstr, poster). 147. Schmidt J, Meisel H, Hjelle B, Capria SG, Vial PA, Padula P, Kruger DH, Ulrich R. Development and evaluation of serological assay for the detection of human infections by New World hantaviruses imported to Europe. 6th Intl Conf on Hantaviruses, HFRS and HPS, Seoul, 23-25 June, 2004 (abstr, poster). 148. Ferrés M, Vial P, Yañez L, Belmar E, Castillo C, Navarrete M, Mansilla R, Calvo M, Sanhueza L, Mardones J, Godoy P, Aldunate R, Ferrer P, Medina R, Valdivieso F, Araya N, Galeno H, Hjelle B, Mertz G. Prospective natural history study of household contacts of persons with acute hantavirus cardiopulmonary syndrome in Chile. Ann Mtg for the Intl Center Trop Dis Res Washington, 19 May 2004. 149. Pascale JM, Bayard V, Zaldívar Y, Mendoza Y, Mojica D, Armien A, Gracia F, Quiroz E, Castillo Z, Muñoz C, Hjelle B, Koster F, Mertz G, Armien B. Epidemiology of hantavirus infection in Panama. Fifth Ann Intl Mtg Hantavirus Ecol Dis Chile, Viña del Mar, Chile, 1-2 Apr 2004 (abstr, oral). 150. Xiao R, Koster F, Ye C, Stidley C, Ponce L, Mertz G, Hjelle B. Sin Nombre viral RNA load correlates with disease severity in patients with the hantavirus cardiopulmonary syndrome 6th Intl Conf on Hantaviruses, HFRS and HPS, Seoul, 23-25 June, 2004 (abstr, poster). 151. Larson R, Brown D, Ye C, Hjelle B. Peptide antagonists of β3 integrin-mediated cell entry of Sin Nombre virus. 6th Intl Conf on Hantaviruses, HFRS and HPS, Seoul, 23-25 June, 2004 (abstr, poster).

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152. Goade DE, Nofchissey RA, Hanfelt J, Hjelle B, Leach JK. Sin Nombre virus nucleocapsid Antigen is sufficient to cause myocardial contractile dysfunction in a rat papillary muscle model. 6th Intl Conf on Hantaviruses, HFRS and HPS, Seoul, 23-25 June, 2004 (abstr, oral). 153. Prescott JB, Hjelle B. Regulation of human endothelial cell gene expression during Sin Nombre virus infection. 6th Intl Conf on Hantaviruses, HFRS and HPS, Seoul, 23-25 June, 2004 (abstr, poster). 154. Medina RA, Mirowsky K, Hamel R, Goade D, Hjelle B. Ribavirin and human convalescent sera, but not anti-β3 integrin antibody, prevent infection by Sin Nombre virus in the deer mouse model. 6th Intl Conf on Hantaviruses, HFRS and HPS, Seoul, 23-25 June, 2004 (abstr). 155. Goade DE , Nofchissey RA, Webb D, Welsh B, Hanfelt J, Hjelle B. a longitudinal, prospective study of survivors of hantavirus infections in the US. 6th Intl Conf on Hantaviruses, HFRS and HPS, Seoul, 23-25 June, 2004 (abstr, poster). 156. Hjelle B. New models and technologies for therapeutics and vaccines against hantaviruses. 6th Intl Conf on Hantaviruses, HFRS and HPS, Seoul, 23-25 June, 2004 (abstr, oral plenary). 157. Rangel M, Mirowsky K, Lyons R, Hjelle B. Altered gene expression associated with experimental infection with Sin Nombre hantavirus (SNV) in the deer mouse (Peromyscus maniculatus) model. American Soc for Virology 23rd Ann Mtg July 10-14 2004 Montreal Quebec Canada (abstr, poster). 158. Goade D, Nofchissey RA, Webb D, Hanfelt J, Hjelle B. A longitudinal, prospective study of survivors of hantavirus infections in the US. 53rd Ann Mtg of the Amer Soc Trop Med Hyg Miami, 7-11 November 2004 (abstr 551, poster). 159. Prescott J, Hjelle B. Induction of innate immune response genes by Sin Nombre hantavirus does not require viral replication. ASM Conf Viral Imm Evasion 8-12 March 2005 Acapulco (abstr, poster). 160. Schountz T, Prescott J, Willis D, Mirowsky K, Coons T, Hjelle B. Isolation of nucleocapsid-specific T cells from Sin Nombre virus-infected deer mice. ASM Rocky Mtn Br, Denver, 16 Apr 2005 (abstr, oral). 161. Vial PA., Ferrés M, Valdivieso F, Belmar E, Castillo C, Díaz R, Sholtz L, Calvo M, Donoso S, Hjelle B, Mertz G. Interim analysis of methylprednisolone randomized trial for hantavirus cardiopulmonary syndrome: new alternatives for preemptive therapy may be possible through early detection of hantavirus infection by real time RT-PCR. 14th NIAID International Centers for Trop Dis Res Network, Bethesda, MD May 17-19, 2005 (abstr, oral).

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162. Larson R, Brown DC, Ye C, Hjelle B. Peptide antagonists that inhibit Sin Nombre and Hantaan virus entry through the β3 integrin receptor. Intl Cong Virol 05-IUMS-A-1050-ASM, San Francisco 23-28 July 2005 (abstr, control no 1050). 163. Medina, R, Mirowsky, K, Hjelle, B. Ribavirin and human convalescent plasma, but not anti-β3 integrin antibody, inhibit infection by Sin Nombre virus in the deer mouse model. Intl Cong Virol 05-IUMS-A-1050-ASM, San Francisco 23-28 July 2005 (abstr oral, contr no 2246). 164. Prescott JB, Hjelle B. UV-killed Sin Nombre virus elicits a strong antiviral response in human endothelial cells. Intl Cong Virol 05-IUMS-A-1050-ASM, San Francisco 23-28 July 2005 (abstr poster). 165. Valdivieso F, Vial PA, Ferres M, Ye C, Goade D, Cuiza A, Hjelle B. Deteccion de anticuerpos neutralizantes homo y heterotipicos en sobrevivientes de infeccion por hantavirus Andes y Sin Nombre. XXII Congreso Chileno de Infectologia, Puerto Varas, Chile, 26-29 October 2005. 166. Prescott J, Ye C, Hjelle B. Innate immune responses to Sin Nombre virus components suggest that endothelial cells recognize a specific pathogen-associated molecular pattern (PAMP) in the viral particle. 54th Ann Mtg of the Amer Soc Trop Med Hyg Washington December 11- 15, 2005 (abstr 595 oral). 167. Medina R, Hjelle B. Sin Nombre hantavirus infection in neonatal deer mouse (Peromyscus maniculatus) astrocytes. Mtg of ASM Rio Grande Br, Socorro NM 10-11 Feb 2006 (abstr). 168. Medina RA, Hjelle B. Sin Nombre hantavirus infection in neonatal deer mouse (Peromyscus maniculatus) astrocytes. Keystone Symp on Cell Biol Vir Entry, Replication & Pathogenesis (C4), 24 Feb – 1 Mar 2006, Santa Fe (abstr, poster). 169. Zvirbliene A, Samonskyte L, Petraityte R, Kucinskaite I, Gedvilaite A, Razanskiene A, Schmidt J, Mertens M, Hjelle B, Sasnauskas K, Ulrich R. Epitope specificity of monoclonal antibodies raised against a segment of hantavirus nucleocapsid protein displayed on chimeric virus-like particles. 13th Intl Mtg on Neg Strand Viruses, 17-22 Jun 2006, Salmanca, Spain (abstr). 170. Medina R, Hjelle B. Sin Nombre hantavirus infection in neonatal deer mouse (Peromyscus maniculatus) astrocytes. 13th Intl Conf on Neg Strand Viruses, Salmanca, Spain, 17-22 Jun 2006 (abstr, poster session 4).

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171. Prescott J, Ye C, Hjelle B. Sin Nombre virus is recognized via a specific pathogen-associated molecular pattern (PAMP) that induces an innate immune response. 13th Intl Conf on Neg Strand Viruses, Salmanca, Spain, 17-22 Jun 2006 (abstr, poster session 3). 172. Manigold T, Reyes L, Naves R, Cuiza A, Marco C, Ferres M, Hjelle B, Castillo C, Valdivieso F, Vial P. Analysis of the Memory T cells Response in Chilean Patients With Past Andes Hantavirus Infection. Ann Mtg of Div Microbiol and Infect Dis, NIH, Bethesda, MD 31 May- 2 Jun 2006 (abstr).

173. Prescott J, Ye C, Hjelle B Neither TLR-3 nor RIG-I are sufficient for recognition of the pathogen-associated molecular pattern (PAMP) that initiates an innate immune response to Sin Nombre hantavirus 55th Ann Mtg of the Amer Soc Trop Med Hyg Atlanta November 12- 16, 2006 (abstr 679 oral). 174. Terán F, Pardo E, Medina R, Hjelle B, Ferrés M, Castillo C, Valdivieso F, Vial P, Manigold T. Identificación y caracterización funcional de anticuerpo contra G1 de hantavirus Andes. Ann. Mtg.of Sociedad Chilena de Infectología, Viña del Mar, Chile, 8-10 Nov 2006 (abstr). 175. Schountz T, Oko L, Mirowsky-Garcia KM, Prescott J, Hjelle B. Regulatory T cell-like responses in deer mice infected with Sin Nombre virus. 55th Ann Mtg of the Amer Soc Trop Med Hyg Atlanta November 12- 16, 2006 (abstr 2626 poster) . 176. Torres-Perez F, Medina RA, Palma RE, Hjelle B, Cook JA. Population and ecogeographic genetic structure of O. longicaudatus and Andes virus in three major Chilean ecoregions. 87th Ann Mtg of Amer Soc Mamm, Albuquerque, NM, 6-10 Jun 2007 (abstr). 177. Buranda T, Wu Y, Acuna-Retamar M, Prescott J, Hall P, Hjelle B. Marked variation in recognition of the Sin Nombre virus pathogen-associated molecular pattern (PAMP) among human B cell lines. VII Intl Conf HFRS, HPS, and Hantavirus, Buenos Aires 13-15 Jun 2007 (abstr). 178. Ferrés M, Vial PA, Marco C, Yañez L, Godoy P, Castillo C, Hjelle B, Delgado I, Lee SJ, Mertz GJ and the Andes Virus Household Contacts Study Group. Prospective evaluation of household contacts of persons with hantavirus cardiopulmonary syndrome in Chile. VII Intl Conf HFRS, HPS, and Hantavirus, Buenos Aires 13-15 Jun 2007 (abstr). 179. Medina RA, Hall P, Hjelle B. Efficient in vitro infection of primary deer mouse (Peromyscus maniculatus) cells by Sin Nombre hantavirus. VII Intl Conf HFRS, HPS, and Hantavirus, Buenos Aires 13-15 Jun 2007 (abstr).

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180. Hall PR, Malone L, Sillerud LO, Ye C, Hjelle B, Larson RS. NMR solution structure of a novel cyclic pentapeptide inhibitor of Sin Nombre virus. VII Intl Conf HFRS, HPS, and Hantavirus, Buenos Aires 13-15 Jun 2007 (abstr). 181. Prescott J, Hall PR, Bondu-Hawkins V, Ye C, Hjelle B. Activation of innate immune response to Sin Nombre hantavirus occurs independently of entry, IRF 3, and known pattern recognition receptors. VII Intl Conf HFRS, HPS, and Hantavirus, Buenos Aires 13-15 Jun 2007 (abstr). 182. Prescott J, Hall PR, Bondu-Hawkins V, Ye C, Hjelle B. Activation of innate immune response to Sin Nombre hantavirus occurs independently of entry, IRF 3, and described pattern recognition receptors. 26th Ann Mtg of Amer Soc Virol Corvallis, 14-18 Jul 2007 (abstr). 183. Hjelle B. Hantaviruses: Modeling their relationships to native host species and humans. 15th Conf on HIV Dynamics and Evol, Santa Fe, 27-30 Apr 2008 (abstr). 184. Hall P, Acuna M, Ye C, Duran W, Bondu-Hawkins V, Hjelle B. Engagement of Sin Nombre Hantavirus by human pattern recognition receptor leads to rapid induction of interferon-stimulated genes. Intl Congr Virology (IUMS) Mtg Istanbul Turkey 10-15 Aug 2008 (abstr). 185. Torres-Perez F, Palma RE, Hjelle B, Cook JA. Contrasting spatial genetics and co-differentiation patterns in hantavirus and associated rodent hosts. Molec Epid Evol Infect Dis (MEEGID) Congr IX Irvine, CA 30 Oct – 1 Nov 2008. 186. Mir M, Panganiban AT, Hjelle BL. Hantavirus nucleocapsid protein: amazing role in virus replication. Amer Soc Virol 28th Ann Mtg July 11-15 2009 Vancouver BC Canada (abstr W27-1 p. 35). 187. Manigold T, Mori A, Graumann R, Llop E, Simon V, Ferrés M, Valdivieso F, Castillo C, Hjelle B, Vial P. High frequencies of effector memory T cells and neutralizing antibodies indicate latent exposure to Andes virus antigens in convalescent Chilean patients. VIII Intl Conf on HFRS, HPS and Hantaviruses, 20-22 May 2010, Athens (abstr). 188. Buranda T, Perez D, Bondu-Hawkins V, Ye C, Sklar LA, Wandinger-Ness A, Hjelle B. UV-killed Sin Nombre Virus binds to decay accelerating factor (DAF/CD55) to induce cytoskeletal remodeling of Vero E6 cells and to access αvβ3 for cellular entry. VIII Intl Conf on HFRS, HPS and Hantaviruses, 20-22 May 2010, Athens (abstr). 189. Brian Hjelle B, Meda Higa M, Chunyan Ye C, Pablo Vial P, Sang-Joon Lee S-J, Greg Mertz G, Robert W. Doms RW, Francisca Valdivieso F. Comparison of BSL2 VSV pseudotype and conventional BSL 3 Andes virus-based assays for titration of neutralizing antibodies in Andes

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virus-infected patients. VIII Intl Conf on HFRS, HPS and Hantaviruses, 20-22 May 2010, Athens (abstr). 190. Ferrés M, Vial P, Marco C, Martínez C, Godoy P, Cuiza A, Valdivieso F, Hjelle B, Mertz G. Presence of Andes virus genome in gingival crevicular fluid during acute hantavirus infection. VIII Intl Conf on HFRS, HPS and Hantaviruses, 20-22 May 2010, Athens(abstr). 191. Schountz T, Acuna-Retamar M, Kedmi S, Prescott J,Torres-Perez F Hjelle B. Transition from inflammatory to anti-inflammatory immune response in deer mice infected with Sin Nombre virus. 14th Intl Neg Strand Viruses Meeting 21-25 Jun 2010, Bruges, Belgium (abstr). 192. Buranda T, Agola J, Perez D, Sklar L, Wandinger-Ness A, Hjelle B. Bidirectional signaling between small molecule Rho family GTPases and integrins is required for cellular entry of virus. Gordon Res Conf on Signaling by Adhesion Receptors, 11-16 July 2010 Colby College, Waterville ME. (abstr)

193. Schountz T, Acuna-Retamar M, Torres Perez F, Kedmi S, Prescott J, Peters S, Hjelle B. Transition from inflammatory to anti-inflammatory immune responses in deer mice infected with Sin Nombre virus. 98th Ann Mtg Amer Soc Immunol, 13-17 May 2011, San Francisco. (abstr) 194. Hjelle B, Li J, Ye C, Jett S, Higa M, Buranda T. VSV Pseudotypes bearing hantavirus glycoproteins retain antigenic and functional characteristics of the parental glycoproteins. 30th Ann Mtg of Amer Soc for Virology, Minneapolis, 16-20 July 2011.