CURRICULUM VITAEDaniel L. Herr, M.S., M.D., F.C.C.M

Associate Professor, Department of SurgeryUniversity of Maryland Medical CenterR Adams Cowley Shock Trauma Center

Date June 27, 2017

Contact Information

Business Address: Department of Surgery 22 S. Greene Street, Suite S4D13Baltimore, Maryland 21202

Business Phone Number: 410-328-1201Cell: 443-834-9911Fax: 410-328-0687Email: dherr@smail.umaryland.edu

Education

1974 B.A., Biology & American Studies, Wittenberg University

1977 Masters of Science – Pharmacology, Thomas Jefferson University

1979 Clinical Training, Royal Hampshire County Hospital

1981 M.D., Medical School, St. George’s School of Medicine

Post Graduate Education and Training

1981 - 1982 Intern, Internal Medicine - Bronx-Lebanon Hospital Center, Einstein Medical College

1982 - 1984 Resident, Internal Medicine (including six months chief), York Hospital

1984 - 1985 Fellowship, Critical Care - Trauma - Maryland Institute for Emergency Medical Services (MIEMSS), University of Maryland Hospital

1985 - 1986 Fellowship, Critical Care - Medical and Surgical - Memorial Sloan-Kettering, Cornell University

Daniel L. Herr, M.D

Certifications

1987 Diplomat, American Board of Internal Medicine1989 Certified, Critical Care Medicine1998 Re-Certified, Critical Care Medicine2009 Certified, Neuro-Critical Care2010 Re-Certified, Critical Care Medicine

Medical Licensures

Maryland, 1984

Employment History

Academic Appointments

1989-2009 Medical Director, Surgical Intensive Care Unit, Washington Hospital Center1990-1997 Medical Director, MedStar Trauma Service, Washington Hospital Center 1997-2003 Chairman Medstar Research Institute IRB2005-2009 Associate Professor Clinical Medicine Georgetown University2009-present Director, Cardiac- Surgical, Heart and Lung Transplant, Cardio/ Pulmonary Assist

Devices ICU, University of Maryland2011-2012 Interim Director NeuroCare ICU, University of Maryland2012-present Chief of Surgical Critical Care Services, University of Maryland

Faculty Appointments

1986 – 2009 Senior attending surgical critical Care, Washington Hospital center2003 –2007 Assistant Vice President Medical Affairs MedStar Research Institute2009-Present Associate Professor, University of Maryland Medical Center

Administrative Appointments

2004 –2007 Medical/Research Consultant Hospira Corporation

Professional Society Memberships 1982-2006 Associate American College of Physicians1985-present Society Critical Care Medicine1986-2002 Medical Society of the District of Columbia1987-1999 American Society of Parental and Enteral Nutrition1987-2004 Critical Care Foundation1988-present American Medical Association2004-present Neurocritical care society2005-2007 Faculty of 1000 – Biology2015-present Reviewer for Critical Care Medicine

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Administrative Service

Institutional Service

1986-2006 Standards Committee, Washington Hospital Center1987-present Chairman, Nutrition Committee, Washington Hospital Center1989-present Chairman, Critical Care Equipment Committee, Chair, Washington Hospital Center1990-present Chairman, Vascular Access Committee1992-2007 Member, Transfusion and Blood Products Committee, Washington Hospital Center1993-2009 Chairman, WHC Vascular Access Committee 1993-present Member, Pharmacy and Therapeutics Committee, Washington Hospital Center1997-present Member, Products Steering Committee, Washington Hospital Center2001-2006 Co-Chairman, Value Analysis Committee, Washington Hospital Center2003-2009 Chairman, Washington Hospital Center Research Committee2003-2009 Chairman, Nutrition Committee2006-2009 Chairman, Organ Donation Initiative2009-present Member, Transfusion Committee, University of Maryland Medical Center2010-present Chairman, Critical Care Operations Committee, University of Maryland Medical

Center2012-present Chairman, Critical Care Value Analysis Committee, University of Maryland

Medical Center2015-present Chairman, Resuscitation Committee, University of Maryland Medical Center

National Service

1990-1993 Chairman, Critical Care Section, Medical Society of the District of Columbia1991-present Society of Critical Care Medicine Ad Hoc Committee for National Critical Care

Data Base1992-1996 Co-Chairman, Society Critical Care Medicine, Committee of Critical Care

Preparedness1993-1997 Society of Critical Care Medicine, Symposium Program Committee1996-1999 American College of Critical Care Medicine, Guidelines for the Definition of an

Intensivist and the Practice of Critical Care Medicine1996-1998 American College of Critical Care Medicine, Task Force for Guidelines for

Standards of Care for Patients with Acute Respiratory Failure on Mechanical Ventilatory Support

1997-2000 Society of Critical Care Medicine, Committee of Electronic Communications1997-2000 Society of Critical Care Medicine, Membership Committee2006-present AMA Physician Consortium for Performance Improvement, SCCM Representative2006-2008 American College of Critical Care Medicine- Nutrition Guidelines Committee2006-2012 American College of Critical Care Medicine- Sedation Guidelines Committee2006-2010 Pay 4 Performance Committee- Society Critical Care Medicine2006-2008 Section Chair- Internal Medicine, Society of Critical Care Medicine2009-2010 The Quality Initiatives and Relationships with External Quality Organizations

Workgroup, SCCM2010-present SCCM Quality and Safety Committee

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Teaching Service

Medical Student Teaching

2013 Attending Physician In-patient Service, Cardiac Surgery Sub-Internship (CSUR 549) 2, 4th year medical students- 4 contact hours daily/semester

Resident and Fellow Teaching

2013 Neuro Critical Care Residency2-4, 1st year residents-8 hours a week

2013 Internal Medicine/ Emergency Medicine Residency2-4, 1st year residents-8 hours a week

2013 Pulmonary Critical Care Residency2-4, 1st year residents-8 hours a week

2013 Surgical Critical Care Residency2-4, 1st year residents-8 hours a week

2013 Cardiac Surgery Critical Care Fellowship Program1 fellow, 1st year fellow-2 hours a week

Grant Support

Active Grants

Extracorporeal Membrane Oxygenation (ECMO) for severe ARDS multicenter, randomized, controlled open trial. Depornet de la Recherche Clinique et du Development Principal Site Investigator.

Safety and Efficacy of Polymyxin B Hemoperfusion (PMX) for Septic Shock (EUPHRATES) NCT01046669 Principal Investigator

A Study to Assess Safety and Efficacy of ELAD in Subjects with Acute Alcoholic Hepatitis Who Have Failed Steroid Therapy NCT01829347 Principal Investigator

Completed Grants

Neuro-Sciences

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Phase III, Randomized, Double-blind, Placebo controlled study of the efficacy, safety and tolerability of a single infusion of MK-6072 (human monoclonal antibody to C. difficile toxin B) and MK-3415A (human monoclonal antibody to C. difficile toxin A and B) in patient receiving Antibiotic therapy for c. difficile Infection (MODIFY II) Merck, Principle Site Investigator

Pilot study: Levetiracetam to Prevent Post-Traumatic Epilepsy, PAR-001-119, National Institute of Neurological disorders and Stroke

ACCELERATE - Phase 2: The evaluation of patients with acute hypertension and intracerebral hemorrhage with intravenous clevidipine treatment

CELEG – Specialized Clinical Center Research (SCCOR: Ventilator-Associated Lung injury: Molecular approaches. Single Nucleotide Polymorphisms in acute lung injury (ALI) Project 3 Genetic Modifiers in ventilator associated lug injury.

NIH Grant – P050 HL 73994-01Safety/Efficacy Study of 15 mg/kg/day Tirilazad Mesylate in North American Women with Subarachnoid Hemorrhage. Principal Investigator.

A Safety Study of Tirilazad Mesylate (6 vs. 10 mg/kg/day) in Male Patients with Subarachnoid Hemorrhage (Phase III). Principal Investigator.

The Safety and Efficacy of Zeneca ZD0859 #1 2% versus High-dose Morphine Sulfate (MS04) Injection for the Sedation of Subjects with Severe Head Injury (Phase III). Principal Investigator

Study of Tirilazad Mesylate (U74, 006F) and Methylprednisolone Sodium Succinate on Patients with Acute Spinal Cord Injury (Phase III). Principal Investigator

A Placebo Controlled Trial to Evaluate the Safety, Tolerability, and Potential Efficacy of Initiating Intravenous Administration of CGS-19755 to Serious Head Trauma Patients Prior to Surgery. Principal Investigator.

Head Injury Tirilazad Trial (HITT): A Multicenter Efficacy Study of Tirilazad Mesylate (U-74, 006F) in Patients with Moderate and Severe Head Injury III. Principal Investigator.

Efficacy/Safety Study of Tirilazad Mesylate (U-74, 006F) in Patients with Subarachnoid Hemorrhage. Principal Investigator.

Multicenter, Randomized, Double-Blind, Parallel Group Trial, Comparing the Efficacy and Safety of Multiple Intravenous Bolus Injections of 5 mg/kg of Selfotel with Placebo in Intubated Severe Closed Traumatic Brain Injured Patients. Principal Investigator.

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Safety and Pharmacokinetics Study of Tirilazad Mesylate at Doses of 10 and 15 mg/kg in Patients with Subarachnoid Hemorrhage. Principal Investigator.

Randomized, double-blind, Placebo-controlled, study of intravenous CI-1009 in Patients with Severe Head Injury. Principal Investigator.

The Effects of Ethanol Levels on the Severity of Intracranial Bleeds. Principal Investigator.

Sedation

Effect of sedation with Dexemedetomidine vs Lorazepam on Acute Brian dysfunction in mechanically ventilated patients. Principal Investigator

A Double Blind, Comparative Randomized Trial to Determine the Safety and Efficacy of Zeneca ZD0859#1 vs. Diprivan ™ (propofol) Injection for Sedation in Post Surgical ICU Subjects (Phase III). Principal Investigator.

A Controlled ICU Clinical Evaluation of urinary Zinc Excretion, renal function, and the Overall Safety Profile of Diprivan with .005% EDTA vs. Standard Sedative Agents without EDTA. Principal Investigator.

Serious Infections

A phase 3, multi-centered, randomized, double-blind, comparative study of the efficacy and safety of Tigecycline versus imipenem/cilastatin for the treatment of subject with nosocomial pneumonia Wyeth, site Principal investigator

A phase 3,open-labeled, non-cooperative study of Tigecycline for the treatment of subjects with selected serious infections due to resistant gram-negative organisms such as enterobacter species, acinetobacter baumanni, and klebsiella pneumonia, sponsor Wyeth, site Principal Investigator

Phase 3, randomized, double blinded, comparative study of micafungin versus placebo as preemptive antifungal therapy in patients in the ICU, Fujisawa Healthcare; Sub Investigator

Linezolid vs. Vancomycin/oxacillin/dicloxcillin in the treatment of catheter related gram-positive bloodstream infections. Pharmacia Principal Investigator

Study of the Treatment of Infections Due to Vancomycin - Resistant Enterococus Falcium (VREF) with Synercid (Phase III). Principal Investigator.

A Randomized, Multi-center, Double-Blind, Double-Dummy Trial Comparing Intravenous CP-1165, 517 Followed by Oral CP-99, 219 with Intravenous Ciprofloxacin Followed by Oral Ciprofloxacin for the Treatment of Nosocomial Pneumonia (Phase III). Principal Investigator.

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Linezolid for the Treatment of Methicillin Resistant Staphylococcus Aureus (MRSA) Infections: an Evaluator-blinded Trial Comparing Linezolid with Vancomycin Alone and Vancomycin Followed by Oral Linezolid. Principal Investigator.

Open Label Comparative Randomized Multi-center Phase III Study of IV Treatment of Synercid Plus Aztreonan vs. Standard Therapy in the Treatment of Adult Nosocomial Pneumonia, due, at least in part to Gram Positive Cocci. Rhone-Poulenc Rorer Principal Investigator.

Phase I Pharmacokinetics and Safety of Seven Days IV Intraconzozole Nanocrystals in ICU Subjects. Janssen Pharmaceutical Principal Investigator.

Sepsis

Safety and efficacy of Drotrecogin ADDRESS trial. Principal Investigator

Double-Blind, Randomized, Placebo-Controlled, Parallel-Group, Multicenter Study of the Safety and Efficacy of Intravenous Taurolidine in Septic Patients Principal Investigator.

ARDS

Phase 2B Study to Evaluate the Safety and Efficacy of rPAF-AH for the Prevention of Acute Respiratory Distress Syndrome in Patients with Severe Sepsis or Severe Traumatic Injuries. Principal Investigator

A Double Blinded, Randomized, Placebo Controlled Study of Inhaled Nitric Oxide in the Treatment of ARDS. . Principal Investigator

Clinical Research Network for the treatment of acute lung injury and acute respiratory distress syndrome (ALI and ARDS) ARDS Network site Investigator, NIH Grant - HHSN268200536170C

Miscellaneous

Multi-Centered Trial of the Bard Silver-Coated endotracheal tube to reduce ventilator associated pneumonia (VAP) sponsor Bard. Site principal Investigator

A Phase IIIb Multi-center Open-Label Randomized Study Comparing the Safety and Efficacy of Dexmedetomidine to Propofol-Base Standard of Care, for ICU Sedation Following CABG, site Principal Investigator

A Randomized, Prospective Trial of Early Foot Impulse Compression in Prophylaxis of Deep Vein Thrombosis in Trauma Patients. Principal Investigator

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Evaluation of Kinetic Therapy in the Prevention of Pulmonary Complications and Skin Breakdown in Critically Ill Trauma Patients. Principal Investigator.

The Prevention of Deep Vein Thrombosis in Acute Spinal Cord Injury Comparing Enoxaparin vs Low Dose Heparin Plus External Pneumatic Compression During the First Two Weeks Followed by Enoxaparin vs Low Dose Heparin for the Remaining Six Weeks (Phase III). Principal Investigator.

The Use of Diaspirin Cross Linked Hemoglobin (DCLHb) for the Avoidance or Reduction of Perioperative Blood Transfusions. Principal Investigator

Comparison of the Efficacy, Safety and Economic Outcomes of Cardizem IV and Digoxin IV in the Treatment of Atrial Fibrillation and Atrial Flutter in Post Coronary Artery Bypass Patients (Phase III) Principal Investigator.

Critical Illness Outcome Study (CIOS), A prospective Observational Ecologic Study in US ICU’s US Critical Illness and Injury Trial Group (NIGMS) Sub Principal Ivestigator. NIH NCT01109719

A Multicenter, Randomized, Controlled Pivotal Study to assess the Safety and Efficacy of a Selective Cytopheretic Device (SCD) In patient with Acute Kidney Injury (AKI) Principle site investigator. CytoPherx, Inc

RUBY: Identification and Validation of Biomarkers of Acute Kidney Injury Recovery NCT01868724 Principal Investigator.

S.A.F.E.: BT System Extracorporeal Treatment With Diapact CRRT (SAFEbt) NCT01312675 Principal Investigator

Publications

Peer-reviewed journal articles

1. Triolo AJ, Aponte GE, Herr DL. "Induction of aryl hydrocarbon hydroxylase and forestomach tumors benzo (a) pyrene." Cancer Res. 1977 Sep;37(9):3018-21.

2. Triolo AJ, Lang WR, Coon JM, Lindstrom D, Herr DL. "Effect of the insecticides toxaphene and carbaryl on induction of lung tumors by Benzo (a) pyrene in the mouse." J Toxicol Environ Health. 1982 Apr;9(4):637-49.

3. Herr D, Carlon GC. “Case of embolization by a sheared pulmonary artery catheter tip.” Crit Care Med. 1987 Apr;15(4):337-8.

4. Ochsner MG, Herr D, Drucker W, Champion HR. "A Modified Seldinger technique for peritoneal lavage in trauma patients who are obese." Surg Gynecol Obstet. 1991 Aug;173(2):158-60.

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5. Dries DJ, Jurkovich GJ, Maier RV, Clemmer TP, Struve SN, Weigelt JA, Stanford GG, Herr DL, Champion HR, Lewis FR, et al. "Effect of interferon gamma on infection - related death in patients with severe injuries." Arch Surg. 1994 Oct;129(10):1031-41.

6. Bracken MB, Shepard MJ, Holford TR, Leo-Summers L, Aldrick EF, Fazl M, Fehlings M, Herr DL, Hitchon PW, Marshall LF, Nockels RP, Pascale V, Perot PL Jr, Piepmeir J, Sonntag VK, Wagner F, Wilberger JE, Winn HR, Young W. “Administration of methylprednisolone for 24 or 48 hours or tirilazad mesylate for 48 hours in the treatment of acute spinal cord injury.” JAMA. 1997 May 28; 277 (20):1597-1604.

7. “A Randomized, double-blinded, vehicle-controlled trial of tirilazad in patients with aneurysmal subarachnoid hemmorrhage: a cooperative study in North America,” J. Neruosurg. 86; 474-476, March 1997.

8. Bracken MB, Shepard MJ, Holford TR, Leo-Summers L, Aldrich EF, Fazl M, Fehlings MG, Herr DL, Hitchon PW, Marshall LF, Nockels RP, Pascale V, Perot PL Jr, Piepmeier J, Sonntag VK, Wagner F, Wilberger JE, Winn HR, Young W. “Methylprednisolone or tirilazad mesylate administration after acute spinal cord injury: 1-year follow up.” J Neurosurg. 1998 Nov;89(5):699-706.

9. Kelly DF, Goodale DB, Williams J, Herr DL, Chappell ET, Rosner MJ, Jacobson J, Levy ML, Croce MA, Maniker AH, Fulda GJ, Lovett JV, Mohan O, Narayan RK. “Propofol in the treatment of moderate and severe head injury: a randomized, prospective double-blinded pilot trial.” J Neurosurg. 1999 Jun;90(6):1042-52.

10. Bracken MB, Aldrick EF, Herr DL, Hitchon PW, Holford TR, Marshall LF, Nockels RP, Pascale V, Shepard MJ, Sonntag VK, Winn HR, Young W. “Clinical measurement, statistical analysis, and risk-benefit: controversies from trials of spinal injury.” J Trauma 2000 Mar;48(3):558-61.

11. Herr DL, Kelly K, Hall JB, Ulatowski J, Fulda GJ, Cason B, Hickey R, Nejman AM, Zaloga GP, Teres D. “Safety and efficacy of propofol with EDTA when used for sedation of surgical intensive care unit patients.” Intensive Care Med. 2000; 26 Suppl 4:S452-62.

12. Bracken MB, Aldrich EF, Herr DL, Hitchon PW, Holford TR, Marshall LF, Nockels RP, Pascale V, Shepard MJ, Sonntag VK, Winn HR, Young W. “Clinical measurement, statistical analysis, and risk-benefit: controversies from trials of spinal injury.” J Trauma. 2000 Mar;48(3):558-61.

13. Czop M, Herr DL. “Green Skin discoloration associated with multiple organ system failure.” Crit Care Med. 2002 Mar;30(3):598-601.

14. Stevens DL, Herr D, Lampiris H, Hunt JL, Batts DH, Hafkin B. “Linezolid versus vancomycin for the treatment of methicillin-resistant Staphylococcus aureus infections.” Clin Infect Dis. 2002 Jun 1;34(11):1481-90.

15. Herr DL, Sum-Ping ST, England M. “ICU sedation after coronary artery bypass graft surgery: dexmedetomidine-based versus propofol-based sedation regimens.” J Cardiothorac Vasc Anesth. 2003 Oct;17(5):576-84.

16. Zimbroff DL, Allen MH, Battaglia J, Citrome L, Fishkind A, Francis A, Herr DL, Hughes D, Martel M, Preval H, Ross R. “Best clinical practice with ziprasidone IM: update after 2 years of experience.” CNS Spectr. 2005 Sep;10(9)1-15. Review.

17. Pandharipande PP, Pun BT, Herr DL, Maze M, Girard TD, Miller RR, Shintani AK, Thompson JL, Jackson JC, Deppen SA, Stiles RA, Dittus RS, Bernard GR, Ely EW. “Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in

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mechanically ventilated patients: the MENDS randomized controlled trial.” JAMA. 2007 Dec 12;298(22):2644-53.

18. “Dexmedetomidine vs midazolam for sedation of critically ill patients: a randomized trial.” Riker RR, Shehabi Y, Bokesch PM, Ceraso D, Wisemandle W, Koura F, Whitten P, Margolis BD, Byrne DW, Ely EW, Rocha MG;SEDCOM (Safety and Efficacy of Dexmedetomidine Compared with Midazolam) Study Group. JAMA. 2009 Feb 4;301(5):489-99.

19. Herr DL, Badjatia N. “Therapeutic temperature management: why, who, when, where, and how.” Crit Care Med. 2009 Jul;37(7 Suppl):S185.

20. Egol A, Shander A, Kirkland L, Wall MH, Dorman T, Dasta J, Bagwell S, Kaufman D, Matthews P Jr, Greenwald BM, Herr DL, Stavish C, Thompson C, Fahy BG; Society of Critical Care Medicine. “Pay for performance in critical care: an executive summary of the position paper by the Society of Critical Care Medicine.” Crit Care Med. 2009 Sep;37(9):2625-31.

21. Pandharipande PP, Sanders RD, Girard TD, McGrane S, Thompson JL, Shintani AK, Herr DL, Maze M, Ely EW; MENDS investigators. “Effect of dexmedetomidine versus lorazepam on outcome in patients with sepsis: an a priori-designed analysis of the MENDS randomized controlled trial.” Crit Care. 2011;15(1):402.

22. Shomali ME, Herr DL, Hill PC, Pehlivanova M, Sharretts JM, Magee MF. “Conversion from intravenous insulin to subcutaneous insulin after cardiovascular surgery: transition to target study.” Diabetes Technol Ther. 2011;13(2):121-6.

23. National Heart, Lung, and Blood Institute Acute Respiratory Distress Syndrome (ARDS) Clinical Trials Network, Rice TW, Wheeler AP, Thompson BT, Steingrub J, Hite RD, Moss M, Morris A, Dong N, Rock P. “Initial trophic vs full enteral feeding in patients with acute lung injury: the EDEN randomized trial.” JAMA. 2012 Feb 22;307(8):795-803.

24. Klein P, Herr D, Pearl PL, Natale J, Levine Z, Nogay C, Sandoval F, Trzcinsky S, Atabaki SM, Tsuchida T, van den Anker J, Soldin SJ, He J, McCarter R. “Results of phase II pharmacokinetic study of levetiracetam for prevention of post-traumatic epilepsy.” Epilepsy Behav. 2012 Aug;24(4):457-61.

25. Klein P, Herr D, Pearl PL, Natale J, Levine Z, Nogay C, Sandoval F, Trzcinski S, Atabaki SM, Tsuchida T, van den Anker J, Soldin SJ, He J, McCarter R. “Results of phase 2 safety and feasibility study of treatment with levetiracetam for prevention of posttraumatic epilepsy.” Arch Neurol. 2012 Oct;69(10):1290-5.

26. LeBlanc JM, Kane-Gill SL, Pohlman AS, Herr DL. “Multiprofessional survey of protocol use in the intensive care unit.” J Crit Care. 2012 Dec;27(6):738.e9-17

27. Barr J, Fraser GL, Puntillo K, Ely EW, Gelinas C, Dasta JF, Davidson JE, Devlin JW, Kress JP, Joffee AM, Coursin DB, Herr DL, Tung A, Robinson BR, Fontaine DK, Ramsay MA, Riker RR, Sessler CN, Pun B, Skrobik Y, Jaeschke R; American College of Critical Care Medicine. “Clinical practice guidelines for the management of pain, agitation, and delirium in adult patients in the intensive care unit.” Crit Care Med. 2013 Jan;4(1):263-306.

28. Barr J, Fraser GL, Puntillo K, Ely EW, Gelinas C, Dasta JF, Davidson JE, Devlin JW, Kress JP, Joffee AM, Coursin DB, Herr DL, Tung A, Robinson BR, Fontaine DK, Ramsay MA, Riker RR, Sessler CN, Pun B, Skrobik Y, Jaeschke R; American College of Critical Care Medicine. “Clinical practice guidelines for the management of pain, agitation,

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and delirium in adult patients in the Intensive Care Unit: executive summary.” Am J Health Syst Pharm. 2013 Jan 1;70(1):53-8.

29. Lee JD, Bonaros N, Hong PT, Kofler M, Srivastava M, Herr DL, Lehr EJ, Bonatti J. “Factors influencing hospital length of stay after robotic totally endoscopic coronary artery bypass grafting.” Ann Thorac Surg. 2013 Mar;95(3):813-8.

30. Joffe AM, Hallman M, Gelinas C, Herr DL, Puntillo K. “Evaluation and Treatment of pain in critically ill adults.” Respir Crit Care Med. 2013 Apr;34(2):189-200.

31. Galvagno SM Jr, Hong CM, Lissauer ME, Baker AK, Murthi SB, Herr DL, Stein DM. “Practical considerations for the dosing and adjustment of continuous renal replacement therapy in the intensive care unit.” J Crit Care. 2013 Dec;28(6):1019-26.

32. Polito CC, Cribbs SK, Martin GS, O’Keeffe T, Herr D, Rice TW, Sevransky JE. “Navigating the institutional review board approval process in a multicenter observational critical care study.” Crit Care Med. 2014 May;42(5):1105-9.

33. Greenwood JC, Herr DL. “Mechanical circulatory support.” Emerg Med Clin North AM. 2014 Nov;32(4):851-69.

34. Kon ZN, Wehman PB, Gibber M, Rabin J, Evans CF, Rajagopal K, Herr D, Iacono A, Garcia JP, Griffith BP. “Venovenous extracorporeal membrane oxygenation as a bridge to lung transplantation: successful transplantation after 155 days of support.” Ann Thorac Surg. 2015 Feb;99(2):704-7.

35. Kotloff RM, Blosser S, Fulda GJ, Malinoski D, Ahya VN, Angel L, Byrnes MC, DeVita MA, Grissom TE, Halpern SD, Nakagawa TA, Stock PG, Sudan DL, Wood KE, Anillo SJ, Bleck TP, Eidbo EE, Fowler RA, Glazier AK, Gries C, Hasz R, Herr D, Khan A, Landsberg D, Lebovitz DJ, Levine DJ, Mathur M, Naik P, Niemann CU, Nunley DR, O’Connor KJ, Pelletier SJ, Rahman O, Ranjan D, Salim A, Sawyer RG, Shafer T, Sonneti D, Spiro P, Valapour M, Vikraman-Sushama D, Whelan TP; Society of Critical Care Medicine/American College of Chest Physicians/Association of Organ Procurement Organizations Donor Management Task Force. “Management of the potential organ donor in the ICU: Society of Critical Care Medicine/American College of Chest Physicians/Association of Organ Procurement Organizations Consensus Statement.” Crit Care Med. 2015 Jun;43(6):1291-325.

36. Kon ZN, Dahi S, Evans CF, Byrnes KA, Bittle GJ, Wehman B, Rector RP, McCormick BM, Herr DL, Sanchez PG, Pham SM, Griffith BP. “Class III obesity is not a contraindication to venovenous extracorporeal membrane oxygenation support.” Ann Thorac Surg. 2015 Nov;100(5):1855-60.

37. Mazzeffi M, Kiefer J, Greenwood J, Tanaka K, Menaker J, Kon Z, Sanchez P, Pham S, Herr D. “Epidemiology of gastrointestinal bleeding in adult patients on extracorporeal life support.” Intensive Care Med. 2015 Nov;41(11):2015.

38. Kon ZN, Dahi S, Evans CF, Byrnes KA, Bittle GJ, Wehman B, Rector RP, McCormick BM, Herr DL, Sanchez PG, Pham SM, Griffith BP. “Long-Term venovenous extracorporeal membrane oxygenation support for acute respiratory distress syndrome.” Ann Thorac Surg. 2015 Dec;100(6):2059-63.

39. Mazzeffi M, Greenwood J, Tanaka K, Menaker J, Rector R, Herr D, Kon Z, Lee J, Griffith B, Rajagopal K, Pham S. “Bleeding, transfusion, and Mortality on extracorporeal life support: ECLS working group on thrombosis and hemostasis.” Ann Thorac Surg. 2016 Feb;101(2):682-9.

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40. Mazzeffi M, Kon Z, Sanchez P, Herr D. “Impact of acute liver failure on mortality during adult ECLS.” Intensive Care Med. 2016 Feb;42(2):299-300.

41. Mazzeffi MA, Sanchez PG, Herr D, Krause E, Evans CF, Rector R, McCormick B, Pham S, Taylor B, Griffith B, Kon ZN. “Outcomes of extracorporeal cardiopulmonary resuscitation for refractory cardiac arrest in adult cardiac surgery patients.” J Thorac Cardiovasc Surg. 2016 Jun 23.5223(16):30644-4.

Book Chapters

1. Zaloga Mosby, “Nutrition in Critical Care” Trace Elements, 1994.2. Herr, D., Burman, K., “Endocrine Management of the Cardiac Surgical Patient”

New Horizons, 7#4, 542-550, 19993. Tisherman SA, Herr D, Spain DA, Patterson A, Luchette F, eds. “Coding and

Billing” Scientific American Critical Care of the Surgical Patient. Ecker, Philadelphia, PA. In Press, 2017.

Abstracts

1. Effects of Acute Alcohol Intoxication on Outcome of Head Injury. Dr. Kelly, Dr. Herr. Critical Care Medicine 23/#1, Jan. 1995, oral presentation.

2. A New Catheter for Continuous Arterial-Venous Hemofiltration. Dr. Herr. Blood Purification 15:143, 1997.

3. Simple Method for Identifying Potential Clinical Research Candidates Using Bedside Clinical Computer System (BCSS), Daniel Herr, MD, Arthur St. André, MD, Russell Zaccari, Critical Care Medicine 26#1. January 1998, A66.

4. Generating TISS-28 Scores Directly from Hospital Billing Data: Validation on New hospital Data. Dr. Herr, Clermont, Angus. Critical Care Medicine 26#1. January 1998, A66.

5. A Randomized prospective Trial of Early Foot Compression in the Prophylaxis of Deep Vein Thrombosis in Trauma Patients. EAST conference, January 14, 1998.

6. Thyroid. No Correlation Exists Between Thyroid Hormone Levels and Atrial Fibrilation in Patients Undergoing CABG, Acosta, J., Williams, M., Burman, K., Herr, D., Critical Care Medicine 27#12. 1999, A77.

7. Gender Differences Exist in Serum Cortisol Levels in Critical Surgical Patients, Williams, M., Acosta, J., Herr, D., Critical Care Medicine 27#12. 1999, A147.

8. A Multi-Institutional Study to Evaluate the Use of Kinetic Therapy in the Prevention of Pulmonary Complications in Traumatic Head Injury, Herr, D., Pierre, C., Jablonski, K., Critical Care Medicine 27#12. 1999, A32.

9. Phase 3, Multi-center, Open Label, Randomized Study comparing the Safety/Efficacy of Dexmedetomidine to Propofol, for lCU Sedation after CABG Surgery, Crit Care Medicine, 2001.

10. Characterization And Management Dexmedetomidine-Induced Hypotension Following CABG, Jordan V., Herr D, Crit Care Medicine, 2002.

11. Does Diabetes Increase Hemodynamic Lability in patients receiving Dexemedetomidine, Jordan V. Herr D, ASA 203, presentation, 2002.

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12. Use of Dexemedetomidine for the treatment of paroxysmal autonomic dysfunction in TBI patient. Herr D. Neurocritical Care society symposium, 2006.

13. Safety of Dexemedetomidine for > 24hours in Patients with SAH and ventricular drains. Herr D, Neurocritical care society symposium 2007.

14. Use of High Flow Nasal cannula (HFNC) O2 therapy for failed extubation post cardiac surgery, SCCM national symposium 2011.

15. Multi-professional survey of protocol use in the ICU. Jaclyn Le Blanc, Sandra Kane-Dill, Daniel Herr SCCM National symposium, 2011.

Major Invited Speeches

1. Innovative Approach to Pulmonary Hygiene, Maryland/District of Columbia Society of Respiratory Care

2. Update on Critical Issues in Trauma Surgery, Emerging Applications of CRRT, Suburban Hospital, Bethesda, MD

3. SCCM National Symposium, Protocol Driven Care of the Head Injured Patient, San Diego, CA

4. SCCM National Symposium, Trace Elements and Critical Care Nutrition, New Orleans, LA

5. Symposium, “Fat and the Healthy American Diet - A Capital Perspective, Washington, DC6. Trauma Grand Rounds: “Current Therapies and Emerging Concepts in the Treatment of

Closed Head Injuries in the ICU”, Suburban Hospital, Bethesda, MD7. Third Annual National Clinical Care Conference, Air Medical Physician Association

(AMPA) “Acute Medical Management of the Multiply Injured Patient” 8. CAVH-D Practical Applications and Controversies, Morristown Hospital, New Jersey,

Trauma Grand Rounds 9. Critical Care of the Spinal Cord Injury Patient. Norwalk Hospital, Connecticut, Trauma

Symposium. 10. Free Radicals and Antioxidants in the Critically Ill Patient. “TRENDS” conference, Septa

AACM, Philadelphia. 11. Pathogenesis of Multiple Organ Dysfunction Syndrome (MODS), “TRENDS” conference,

Septa AACM, Philadelphia. 12. Cardiovascular Management of the Closed Head Injury Patient. University of Virginia,

Neurosurgical Grand Rounds. 13. Free Radicals and Antioxidants. Their role in critical care patients. “TRENDS”

Conference Septa AACN, Philadelphia. 14. Free Radicals and Brain Injury. Management of Brain Injury Conference, Washington

Hospital Center. 15. Management of the Brain Injured Patient. Grand Rounds, City Hospital, Martinsburg West

Virginia.16. Critical Care in the Neurosurgical ICU “No Brain in an Island” Annual National

Neurosurgical Meeting, Washington, DC 17. Program Coordinator, “Surgical Critical Care for the Consulting Internist”, Washington

Hospital Center.

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Daniel L. Herr, M.D

18. Baltimore Region Association of dietitians, John Hopkins Hospital, “Enteral vs. Parenteral Nutrition”

19. Suburban Hospital, "Critical Care of the Elderly Trauma Patient"20. Bethesda Naval Hospital, "Prostaglandins and Nutrition" 21. Walter Reed Army, "Reverse I:E Ventilations in ARDS"22. Greater Laurel-Beltsville Hospital Trauma Symposium, “Trauma Assessment in the Field

Medical Considerations 23. National Rehabilitation Hospital Conference on Traumatic Head Injury, "Respiratory

Problems in the Head Injured Patient" 24. Mary Washington Hospital - Trauma Rounds, "Medical Problems in Trauma Patients" 25. Washington Hospital Center, "Nutrition and Multi-System Organ Failure" 26. York Hospital, "The Internist in Surgical Intensive Care" 27. 5th World Congress on Emergency and Disaster Medicine - Rio de Janeiro, "Nutritional

Support in the Trauma Critically Ill Patient. A New Insight" 28. Washington Hospital Center, "Surgical Critical Care of the Esophagogastrectomy Patient" 29. Memorial Sloan Kettering, "The Use of Continuous Arteriovenous Hemofiltration in the

Post Surgical Patient" 30. York Hospital, "Non-Bacterial Endocarditis" 31. York Hospital, "Fat Embolism Syndrome"

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