D E C E M B E R 1 , 2018 C U R R I C U L U M V I T A E

VADIM BACKMAN

NORTHWESTERN UNIVERSITY BIOMEDICAL ENGINEERING DEPARTMENT

2145 SHERIDAN ROAD, EVANSTON, IL 60208 VOICE: (847) 491-3536 FAX: (847) 491-4928 E-MAIL: V-BACKMAN@NORTHWESTERN.EDU

EDUCATION

Harvard University - Massachusetts Institute of Technology, Cambridge, MA Division of Health Sciences and Technology, Ph.D. in Medical Engineering and Medical Physics, 2001.

Massachusetts Institute of Technology, Cambridge, MA. M.S. in Physics, 1998. St. Petersburg Polytechnic Institute, St. Petersburg, Russia. M.S. in Physics, 1996, B.S. in Physics, With Highest Honors, 1994.

PROFESSIONAL EXPERIENCE

Center for Physical Genomics and Engineering July 2018 - present Director Northwestern University, McCormick School of Engineering & Applied Sciences Center for Developmental Therapeutics July 2018 - present Associate Faculty Director Northwestern University, Chemistry of Life Processes Institute Northwestern University, Evanston, IL January 2018 - present Professor of Biochemistry and Molecular Genetics Feinberg School of Medicine Northwestern University, Evanston, IL November 2017 - present Professor of Medicine, Division of Hematology/Oncology Feinberg School of Medicine Northwestern University, Evanston, IL. September 2012 – present Walter Dill Scott Professor of Biomedical Engineering, Biomedical Engineering Department. Robert H. Lurie Comprehensive Cancer Center, December 2008 – present Northwestern University, Evanston, IL. Program Leader, Cancer and Physical Sciences Program Nanocytomics, LLC, Evanston, IL April 2012 – present Chairman and Co-Founder

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American BioOptics, LLC, Evanston, IL June 2006 – present Chairman and Co-Founder Northwestern University, Evanston, IL. September 2006 – August 2012 Professor, Biomedical Engineering Department. Evanston Northwestern Hospital, Evanston, IL. September 2002 – 2013 Member of Professional Staff, Department of Medicine, Section of Gastroenterology Northwestern University, Evanston, IL. September 2001 – August 2006 Assistant Professor, Biomedical Engineering Department.

HONORS

Cozzarelli Prize, National Academy of Sciences (2017). Fellow, Farley Center for Entrepreneurship and Innovation (2016, 2013). Liz and Eric Lefkofsky Scholar (2015). Dorothy Ann and Clarence L. Ver Steeg Distinguished Research Fellow (2015). Faculty Honor Roll, Northwestern University Associated Student Government (2011). Faculty Honor Roll, Northwestern University Associated Student Government (2010). Fellow, American Institute for Medical and Biological Engineering (AIMBE) (2009). Faculty Honor Roll, Northwestern University Associated Student Government (2008). Faculty Honor Roll, Northwestern University Associated Student Government (2007). Phi Beta Psi Cancer Research Award (2006). Faculty Honor Roll, Northwestern University Associated Student Government (2005). The Wallace H. Coulter Foundation Early Career Translational Research Award in Biomedical

Engineering (2005, 2007). Citation for “Research Excellence”, Northwestern University (2005). Selected as one of the Top 100 Young Innovators in the World by MIT's Technology Review

Magazine (2004). NSF CAREER Award (2003). NSF Young Investigator Best Paper Award in New Techniques in Biomedical Optics and

Medical Imaging (2002). General Motors Cancer Research Scholar Award (2002). Phi Beta Psi Cancer Research Award (2002). Poitras Pre-doctoral Fellowship in Biomedical Engineering and Biophysics (2000). Lester Wolfe Fellowship in Biomedical Optics (1999). Becton Dickenson Fellowship in Medical Engineering (1998). George Soros International Science Foundation Fellowship in Physics (1995, 1996). National Contest for Outstanding M.S. Thesis in Physics (second prize, 1996). Informatics Olympiad (second prize, 1990).

PUBLICATIONS

A. Peer-reviewed Journal Publications 1. S. Gladstein, L.M. Almassalha, L. Cherkezyan, J.E. Chandler, A. Eshein, A. Eid, D. Zhang,

W. Wu, G.M. Bauer, A.D. Stephens, S. Morochnik, H. Subramanian, J.F. Marko, G.A.

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Ameer, I. Szleifer, V. Backman, “Multimodal interferometric imaging of nanoscale structure and macromolecular motion uncovers UV induced cellular paroxysm”, Nature Communications, submitted (2018).

2. R. Liu, W. Song, V. Backman, J. Yi, “A data quality-control protocol for in vivo oximetry in small vessels by visible light optical coherence tomography”, JBO, submitted (2018)

3. W. Wu, L. Almassalha, D. Zhang, H. Roy, I. Szleifer, and V. Backman, “Unraveling the chromatin packing code: physical interactions governing global transcription diversity”, Biophysical Journal, submitted (2018).

4. W. Wu, L.M. Almassalha, D. Zhang, H.K. Roy, I. Szleifer, and V. Backman, “Unraveling supra-nucleosomal physical interactions governing global transcription activity”, PLOS Computational Biology, submitted (2018).

5. A.D. Stephens, P.Z. Liu, L.M. Almassalha, A. Erbas, S.A. Adam, R.D. Goldman, V. Backman, E.J. Banigan, J.F. Marko, “Chromatin compaction state is a major determinant of nuclear blebbing and deformations”, PNAS, submitted (2018).

6. G.M. Bauer, L.M. Almassalha, L. Cherkezyan, A. Kendra, S. Gladstein, J.E. Chandler, B. Seagle, T.V. O’Halloran, H.K. Roy, I. Szleifer, S. Shahabi, and V. Backman, “Chromatin protection therapies: systems therapeutics for increased chemotherapeutic efficacy”, Cancer Research, submitted (2018).

7. V. Konda, S. Ruderman, M. Gonzalez-HabaRuiz, V. Valucka, U. Dougherty, V. Becker, R. Mustafi, A. Singh, A. Skakdagr, D. Almoghrabi, I. Waxman, H.K. Roy, J. Hart, V. Backman, M. Bissonnette, “Effects of Western diet and carcinogenesis on angiogenesis in AOM/DSS-induced colon cancer”, Clinical Cancer Research, submitted (2018).

8. J.A. Winkelmann, G. Spicer, A. Eid, L.M. Almassalha, T.Q. Nguyen, and V. Backman, “Spectral contrast optical coherence tomography angiography enables single-scan vessel imaging”, Light: Science and Applications, accepted (2018).

9. A. Eshein, Y. Li, B. Dong, L. Almassalha, J. Chandler, T.Q. Nguyen, K. Hujsak, V. Dravid, C. Sun, H.F. Zhang and V. Backman, “Sub-10nm imaging of nucleic acids using spectroscopic intrinsic-contrast photon-localization optical nanoscopy (SICLON)”, Optics Letters, 43(23) 5817-5820 (2018).

10. T.D. Swain, S. Lax, N. Lake, H. Grooms, V. Backman, L. Marcelino, “Relating coral skeletal structures at different length scales to growth, light availability to Symbiodinium, and thermal bleaching”, Frontiers in Marine Science, 5:450. doi: 10.3389/fmars.2018.00450 (2018).

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11. S. Thompson, G. Spicer, L. Almassalha, G. Wodarcyk, R. Ellis, J. Chandler, S. Gladstein, D. Zhang, H. Subramanian, R. de la Rica and V. Backman, “Label free localization of nanoparticles in live cancer cells using spectroscopic microscopy”, Nanoscale, 10 19125-19130 (2018).

12. R. Liu, J.A. Winkelmann, G. Spicer, Y. Zhu, A. Eid, G.A. Ameer, V. Backman, and J. Yi, “Single capillary oximetry and pericapillary ultrastructural sensing by dual-band dual-scan inverse spectroscopic optical coherence tomography”, Light: Science and Applications, 7(57) DOI 10.1038/s41377-018-0057-2 (2018).

13. S. Ruderman, A. Eshein, V. Valuckaite, U. Dougherty, A. Almograbi, A. Gomes, A. Singh, B. Pabla, H.K. Roy, J. Hart, M. Bissonnette, V. Konda, and V. Backman, “Early increase in blood supply (EIBS) is associated with tumor risk in the azoxymethane model of colon cancer”, BMC Cancer, 18(1):814 (2018). PMC6090821

14. A. Eshein, A. Radosevich, B. Gould, W. Wu, V. Konda, L. Yang, A. Koons, S. Feder, V. Valuckaite, H. Roy, V. Backman and T. Q. Nguyen, “Fully automated fiber based optical spectroscopy system for use in a clinical setting”, JBO, 23(7) 1-10 (2018).

15. J. Winkelmann, A. Eid, T.Q. Nguyen, T. Bui, J. Yi, and V. Backman, “In Vivo broad-band visible light optical coherence tomography probe enables inverse spectroscopic analysis”, Optics Letters, 43(3) 619-622 (2018).

16. R. Kalman, A. Stawarz, D. Nunes, D. Zhang, M. Delacruz, R. Wali, H. Subramanian, V. Backman, H.K. Roy, “Biophotonic detection of high order chromatin alterations in field carcinogenesis predicts risk of future hepatocellular carcinoma: a pilot study”, PLOS One, 13(5):e0197427 (2018). PMC5957524

17. S. Gladstein, D. Damania, L.T. Smith, V. Gupta, H. Subramanian, D.K. Rex, H.K. Roy, and V. Backman, “Correlating colorectal cancer risk with field carcinogenesis progression using Partial Wave Spectroscopic microscopy”, Cancer Medicine, 10.1002/cam4.1357 (2018).

18. S. Datta, R.M Sherva, M. De La Cruz, M.T. Long, P. Roy, V. Backman, S. Chowdhury and H.K. Roy, “Single nucleotide polymorphism facilitated downregulation of the cohesin stromal antigen-1: implications for colorectal cancer racial disparities”, Neoplasia, 20(3) 289-294 (2018). PMC5883624

19. P. Liu, D. Banigan, L. Almassalha, V. Backman, S. Adam, R. Goldman and J. Marko, “Chromatin histone modifications and rigidity affect nuclear morphology independent of lamins”, Molecular Biology of the Cell, 29(2) 220-233 (2018). PMC5909933

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20. T.D. Swain, E.C. Bold, P.C. Osborn, A.H. Baird, M.W. Westneat, V. Backman, and L.A. Marcelino, “Physiological integration of coral colonies is correlated with bleaching resistance”, Marine Ecology Progress Series, 586 1-10 (2018) (Feature article).

21. L.M. Almassalha, G.M. Bauer, W. Wu, L. Cherkezyan, D. Zhang, A. Kendra, S. Gladstein, J.E. Chandler, D. VanDerway, B. Seagle, A. Ugolkov, D.D. Billadeau, T.V. O’Halloran, A.P. Mazar, H.K. Roy, I. Szleifer, S. Shahabi, and V. Backman, “Macrogenomic engineering via modulation of the scaling of chromatin packing density”, Nature Biomedical Engineering, 1(11) 902-913 (2017). PMC5809134

22. Y. Li, L.M. Almassalha, J.E. Chandler, X. Zhou, Y.E. Stypula-Cyrus, K.A. Hujsak, E.W. Roth, R. Bleher, H. Subramanian, I. Szleifer, V.P. Dravid, V. Backman, “The effects of chemical fixation on the cellular nanostructure”, Experimental Cell Research, 358(2), 253-259 (2017). PMC5726765

23. B. Dong, B. Soetikno, X. Chen, V. Backman, C. Sun, H. Zhang, “Parallel three-dimensional tracking of quantum rods using polarization-sensitive spectroscopic photon localization microscopy”, ACS Photonics, 4(7), 1747-1752 (2017).

24. D.A. Drew, S.M. Chin, K.K. Gilpin, M. Parziale, E. Pond, M.M. Schuck, K. Stewart, M. Flagg, C.A. Rawlings, V. Backman, P.J. Carolan, D.C. Chung, F.P. Colizzo III, M. Freedman, M. Gala, J.J. Garber, C. Huttenhower, D. Kedrin, H. Khalil, D.S. Kwon, S.D. Markowitz, G.L. Milne, N.S. Nishioka, J.M Richter, H.K. Roy, K. Staller, M. Wang, A.T. Chan, “Aspirin intervention for the reduction of colorectal cancer risk (ASPIRED): a study protocol for a randomized controlled trial”, Trials, 18(50) doi: 10.1186/s13063-016-1744-z (2017). PMC5286828

25. Y. Li, D. Zhang, I. Capoglu, D. Damania, K. Hujsak, L. Cherkezyan, E. Roth, R. Bleher, H. Wu, H. Subramanian, V.P. Dravid, V. Backman, “Measuring the autocorrelation function of nanoscale three-dimensional mass-density distribution in individual cells using scanning transmission electron microscopy, atomic force microscopy and a new deconvolution algorithm”, Microscopy and Microanalysis, 23(3), 661-667 (2017). PMC5790320.

26. G.M. Bauer, Y. Stypula-Cyrus, H. Subramanian, L. Cherkezyan, P. Viswanathan, D. Zhang, R. Iyengar, S. Bagalkar, J. Derbas, T. Graff, S. Gladstein, L.M. Almassalha, J. E. Chandler, H.K. Roy, and V. Backman, “The transformation of the nuclear nanoarchitecture in human field carcinogenesis”, Future Science, doi: 10.4155/fsoa-2017-0027 (2017). PMC5583697

27. T.D. Swain, E. DuBois, S.J. Goldberg, V. Backman and L. Marcelino, “Bleaching response of coral species in the context of assemblage response”, Coral Reefs, 36(2) 395-400 (2017). PMC5679474

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28. P. Pradhan, D.J. Park, I. Capoglu, H. Subramanian, D. Damania, L. Cherkezyan, A. Taflove and V. Backman, “Reflection statistics of weakly disordered optical medium when its mean refractive index is different from an outside medium”, Optics Communications, 393, 185-190 (2017).

29. R. Liu, G. Spicer, S. Chen, H.F. Zhang, J. Yi, and V. Backman, “A theoretical model for optical oximetry at the capillary level: exploring hemoglobin oxygen saturation through backscattering of single red blood cells”, JBO, 22(2), 025002 (2017). PMC5290596

30. M. DeLaCruz, S. Ledbetter, X. Sanjib, A. Tiwari, N. Momi, R. Wali, C. Bliss, C. Huang, D. Lichtenstein, S. Bhattacharya, A. Varma-Wilson, V. Backman, H.K. Roy, “Metabolic reprogramming of the premalignant colonic mucosa is an early event in carcinogenesis”, Oncotarget, 8(13), 20543-20557 (2017). PMC5400525.

31. B. Dong, L. Almassalha, B.T. Soetikno, J.E. Chandler, T.Q. Nguyen, B.E. Urban, C. Sun, H.F. Zhang, and V. Backman, “Stochastic fluorescence switching of nucleic acids under visible light illumination”, Optics Express, 25(7), 7929-7944 (2017). PMC5810907

32. L. Cherkezyan, D. Zhang, H. Subramanian, A. Taflove, and V. Backman, “Review of interferometric spectroscopy of scattered light for the quantification of subdiffractional structure of biomaterials”, JBO, 22(3), 030901 (2017). PMC5348632

33. H.K. Roy, V. Turzhitsky, R. Wali, A.J. Radosevich, B. Jovanovic, G. DellaZanna, A. Umar, D.T. Rubin, M.J. Goldberg, L. Bianchi, M. De La Cruz, A. Bogojevic, I.R. Helenowski, L. Rodriguez, R. Chatterton, S. Skripkauskas, K. Page, C.R. Weber, X. Huang, E. Richmond, R.C. Bergan, V. Backman, “Spectral biomarkers for chemoprevention of colonic neoplasia: a placebo-controlled double-blinded trial with aspirin”, Gut, 66(2), 285-292 (2017). PMC5108693

34. L.M. Almassalha, A. Tiwari, P.T. Ruhoff, Y. Stypula-Cyrus, H. Matsuda, M.A. Dela Cruz, J.E. Chandler, C. White, C. Maneval, H. Subramanian, I. Szleifer, H. Roy, and V. Backman, “The global relationship between chromatin physical topology, fractal structure, and gene expression”, Scientific Reports, 7, 41061 (2017). PMC5259786

35. R.K. Wali, N. Momi, M. Dela Cruz, A.H. Calderwood, Y. Stypula-Cyrus, L. Almassalha, A. Chhaparia, C.R. Weber, A. Radosevich, A.K. Tiwari, B. Latif, V. Backman and H.K. Roy, “Higher-order chromatin modulator cohesion SA1 is an early biomarker for colon carcinogenesis: race-specific implications”, Cancer Prevention Research, DOI: 10.1158/1940-6207.CAPR-16-0054 (2016). PMC5093027

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36. J. Yi, Z. Puyang, L. Feng, L. Duan, P. Liang, V. Backman, X. Liu, and H. Zhang, “Optical detection of early damages in retinal ganglion cells in a mouse model of partial optic nerve crush injury”, IOVS, 57(13) 5665-5671 (2016). PMC5089219

37. G. Spicer, S. Azarin, J. Yi, S. Young, R. Ellis, G. Bauer, L. Shea, and V. Backman, “Detection of extracellular matrix modification in cancer models with inverse spectroscopic optical coherence tomography”, Phys Med Biol. 61(19) 6892-6904 (2016). PMC5056859

38. W. Wu, A.J. Radosevich, A. Eshein, T.Q. Nguyen, J. Yi, L. Cherkezyan, H.K. Roy, I. Szleifer, V. Backman, “Using electron microscopy to calculate optical properties of biological samples”, Biomedical Optics Express 7(11), 4749-4762 (2016). PMC5119613

39. L.M. Almassalha, G.M. Bauer, J. Chandler, S. Gladstein, L. Cherkezyan, Y. Stypula-Cyrus, S. Weinberg, D. Zhang, P. Thusgaard Ruhoff, H. Roy, H. Subramanian, N. Chandel, I. Szleifer, V. Backman, “Label-free imaging of the native, living cellular nano-architecture using partial-wave spectroscopic microscopy”, PNAS, 113(42) E6372-E6381 (2016). PMC5081614.

40. T.D. Swain, J. Chandler, V. Backman, & L. Marcelino, “Consensus thermotolerance ranking for 110 Symbiodinium phylotypes: an exemplar utilization of a novel iterative partial-rank aggregation tool with broad application potential”, Functional Ecology 31, 172-183 (2016).

41. T. Swain, J. Vega-Perkins, W. Oestreich, C. Triebold, E. DuBois, J. Henss, A. Baird, M. Siple, V. Backman, and L. Marcelino, “Coral bleaching response index: a new tool to standardize and compare susceptibility to thermal bleaching”, Global Change Biology, 22(7) 2475-88 (2016). PMC5433437

42. S.S. Rao, G.G Bushnell, S.M. Azarin, G. Spicer, B.A. Aguado, J.R. Stoehr, E.J. Jiang, V. Backman, L.D. Shea, & J.S. Jeruss, “Enhanced Survival with Implantable Scaffolds That Capture Metastatic Breast Cancer Cells In Vivo” Cancer Research 76, 5209-5218 (2016). PMC5027988

43. H. Subramanian, P. Viswanathan, L. Cherkezyan, R. Iyengar, S. Rozhok, M. Verleye, J. Derbas, J. Czarnecki, H.K. Roy, V. Backman, “Procedures for risk-stratification of lung cancer using buccal nanocytology”, Biomedical Optics Express, 7(9) 3795-3810 (2016). PMC5030050.

44. B.E. Urban, B. Dong, V. Backman, C. Sun, H.F. Zhang, “Subsurface super-resolution imaging of unstained polymer nanostructures”, Scientific Reports, 6, 28156; doi: 10.1038/srep28156 (2016). PMC4926209.

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45. D. Zhang, I. Capoglu, Y. Li, L. Cherkezyan, J. Chandler, G. Spicer, H. Subramanian, A. Taflove, and V. Backman, “FDTD-based optical microscopy simulation of dispersive media facilitates the development of optical imaging techniques”, JBO, 21(6): 65004 doi:10.1117/1.JBO.21.6.065004 (2016). PMC4901185.

46. B. Dong, L. Almassalha, Y. Stypula-Cyrus, B.E. Urban, T.Q. Nguyen, C. Sun, H.F. Zhang, and V. Backman, “Super-resolution intrinsic fluorescence imaging of chromatin using native, unmodified nucleic acids for contrast”, PNAS, 113(35), 9716-9721 (2016). PMC5024634.

47. J.E. Chandler, Y. Stypula-Cyrus, L. Almassalha, G. Bauer, L. Bowen, H. Subramanian, I. Szleifer, and V. Backman, “Colocalization of cellular nanostructure using confocal fluorescence and partial wave spectroscopy”, Journal of Biophotonics, 10(3), 377-384 (2016). PMC5112146

48. P. Pradhan, D.J. Park, I. Capoglu, H. Subramanian, D. Damania, L. Cherkezyan, A. Taflove, and V. Backman, “Enhancing the sensitivity of mesoscopic light reflection statistics in weakly disordered media by interface reflections”, International Journal of Modern Physics B, 30(23), 1650155 (2016). PMC5754019

49. L.M. Almassalha, G.M. Bauer, J. Chandler, S. Gladstein, I. Szleifer, H.K. Roy, and V. Backman, “The greater genomic landscape: the heterogeneous evolution of cancer”, Cancer Research, 76(19), 5605-9 (2016). PMC5084919.

50. B. Dong, L. Almassalha, B.E. Urban, T.Q. Nguyen, S. Khuon, T.L. Chew, V. Backman, C. Sun, H.F. Zhang, “Super-resolution spectroscopic microscopy via photon localization”, Nature Communications, 7:12290 doi: 10.1038/ncomms12290 (2016). PMC4962472.

51. J. Chandler, L. Cherkezyan, H. Subramanian, V. Backman, “Nanoscale refractive index fluctuations detected via sparse spectral microscopy”, Biomedical Optics Express, 7(3), 883-893 (2016). PMC4866463.

52. T.D. Swain, E. DuBois, A. Gomes, V.P. Stoyneva, A.J. Radosevich, J. Henss, M.E. Wagner, E. Velazquez, J. Traub, B.J. Kennedy, C.M. Janczak, A.A. Grigorescu, M.W. Westneat, K. Sanborn, S. Levine, M. Schick, G. Parsons, J.D. Rogers, V. Backman, L.A. Marcelino, “Skeletal light scattering accelerates bleaching response in reef-building corals”, BMC Ecol., 16(1) (2016). PMC4800776

53. Q. Miao, J. Derbas, A. Eid, H. Subramanian, V. Backman, “Automated cell selection using support vector machine for application to spectral nanocytology”, BioMed Research International, 2016(3), 1-10 doi:10.1155/2016/6090912 (2016). PMC4745312

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54. L. Cherkezyan, D. Zhang, H. Subramanian, A. Taflove, V. Backman, “Reconstruction of explicit structural properties at the nanoscale via spectroscopic microscopy”, JBO, 21(2), 025007 (2016). PMC4756051

55. D. Zhang, L. Cherkezyan, I. Capoglu, H. Subramanian, J. Chandler, S. Thompson, A. Taflove, V. Backman, “Spectroscopic microscopy quantifies the statistics of subdiffractional refractive index fluctuations in media with random rough surfaces”, Optics Letters, 40(21), 4931-4934 (2015). PMC4868404

56. J. Yi, Y. Stypula-Cyrus, C.S. Blaha, H.K. Roy, V. Backman, “Fractal characterization of chromatin decompaction in live cells”, Biophysical Journal, 109(11), 2218-2226 (2015). PMC4675813

57. N. Momi, V. Backman, C. Brendler, H.K. Roy, “Harnessing novel modalities: field carcinogenesis detection for personalizing prostate cancer management”, Future Oncology, 11, 2737-41 (2015). PMC4868392

58. B.E. Urban, B. Dong, Z. Zhang, V. Backman, C. Sun, H.F. Zhang, “Super-resolution two-photon microscopy via scanning patterned illumination”, Physical Review E, 91(4):042703 (2015). PMC4565794

59. A.J. Radosevich, N.N. Mutyal, A. Eshein, T.Q. Nguyen, B. Gould, J. Rogers, M. Goldberg, L. Bianchi, V. Konda, D. Rex, E. Yen, J. Van Dam, H.K. Roy, V. Backman, “Rectal optical markers for in vivo risk stratification of premalignant colorectal lesions”, Clinical Cancer Research, 21(19), 4337-55 (2015). PMC4592390

60. X. Wang, R. Bleher, V. Backman, G. Shekhawat, V. Dravid, “Comparison of sample preparation methods for analysis of mucus-secreting colon cancer cells by scanning electron microscopy”, Microscopy and Microanalysis, 21(3), 185-6 (2015).

61. J. Yi, W. Liu, S. Chen, N. Sheibani, C.M. Sorenson, A.A. Fawzi, V. Backman, R.A. Linsenmeier, H.F. Zhang, “Visible-light optical coherence tomography measures retinal oxygen metabolic response to systemic oxygenation”, Light: Science and Application, 4, e334 (2015). PMC4674267

62. A.J. Radosevich, A. Eshein, T.Q. Nguyen, V. Backman, “Subdiffusion reflectance spectroscopy to measure tissue ultrastructure and microvasculature: model and inverse algorithm”, JBO, 20(9):97002 (2015). PMC4963470

63. S.M. Azarin, J. Yi, R.M. Gower, B.A. Aguado, M.E. Sullivan, A.G. Goodman, E.J. Jiang, S.S. Rao, Y. Ren, V. Backman, J.S. Jeruss, L. Shea, “In vivo capture and label-free detection of early metastatic cells”, Nature Communications, 6:8094 (2015). PMC4563812.

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64. S. Chen, J. Yi, W. Liu, V. Backman, H. Zhang, “Monte Carlo investigation of optical coherence tomography retinal oximetry”, IEEE TBME, 62(9), 2308-2315 (2015). PMC4783381

65. B.D. Jovanovic, H. Subramanian, I.B. Helenowski, H.K. Roy, V. Backman, “Clinical trial laboratory data nested within subject: components of variance, sample size and cost”, Biometrics & Biostatistics International Journal, 2(2):00029 (2015). PMC4596537

66. N.N. Mutyal, A.J. Radosevich, S. Bajaj, V. Konda, U.D. Siddiqui, I. Waxman, M.J. Goldberg, J.D. Rogers, B. Gould, A. Eshein, S. Upadhye, A. Koons, M. Gonzalez, H.K. Roy, V. Backman, “In vivo risk analysis of pancreatic cancer through optical characterization of duodenal mucosa”, Pancreas, 44(5), 735-741 (2015). PMC4464933.

67. H.K. Roy, C. Brendler, H. Subramanian, D. Zhang, C. Maneval, J. Chandler, K. Kaul, B. Helfand, C. Wang, M. Quinn, J. Petkewicz, M. Paterakos, V. Backman, “Nanocytological field carcinogenesis detection to mitigate overdiagnosis of prostate cancer: a proof of concept study”, PLoS One, 10(2): e0115999 (2015). PMC4338151

68. M. Dela Cruz, R.K. Wali, L.K. Bianchi, A.J. Radosevich, S.E. Crawford, L. Jepeal, M.J. Goldberg, J. Weinstein, N. Momi, P. Roy, A.H. Calderwood, V. Backman, H.K. Roy, “Colonic mucosal fatty acid synthase as an early biomarker for colorectal neoplasia: modulation by obesity and gender”, Cancer Epidemiology, Biomarkers & Prevention, 23(11), 2413-2421 (2014). PMC4470400.

69. A. Doronin, A.J. Radosevich, V. Backman, I. Meglinski, “Two electric field Monte Carlo models of coherent back scattering of polarized light”, Journal of the Optical Society of America, 31(11), 2394-2400 (2014).

70. A.J. Radosevich, N.N. Mutyal, J.D. Rogers, B. Gould, T.A. Hensing, D. Ray, V. Backman, H.K.Roy, “Buccal spectral markers for lung cancer risk stratification”, PLoS One, 9(10): e110157 (2014). PMC4192585.

71. M. Patel, A. Gomes, S. Ruderman, D. Hardee, S. Crespo, M. Raimondo, T. Woodward, V. Backman, H.K. Roy, M. Wallace, “Polarization gating spectroscopy of normal-appearing duodenal mucosa to detect pancreas cancer”, Gastrointestinal Endoscopy, 80(5), 786-793 (2014). PMC4241379.

72. R. K. Wali, T. A. Hensing, D. W. Ray, M. Dela Cruz, A. Tiwari, A. Radosevich, L. Jepeal, H.C. Fernando, V. Litle, M. Charlot, N. Momi, V. Backman, H.K. Roy, “Buccal microRNA dysregulation in lung field carcinogenesis: gender-specific implications”, International Journal of Oncology, 45(3), 1209-1215 (2014). PMC4144027.

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73. J. Yi, S. Chen, V. Backman, H.F. Zhang, “In vivo functional microangiography by visible-light optical coherence tomography”, Biomedical Optics Express, 5(10), 3603-3612 (2014). PMC4206328.

74. L. Cherkezyan, H. Subramanian, V. Backman, “What structural length-scales can be detected by the spectral variance of a microscope image?”, Optics Letters, 39(15), 4290-4293 (2014). PMC4317340.

75. Y. Stypula-Cyrus, N.N. Mutyal, M.A. Dela Cruz, D.P. Kunte, A.J. Radosevich, R.K.Wali, H.K. Roy, V. Backman, “End-binding protein 1 (EB1) up-regulation is an early event in colorectal carcinogenesis”, FEBS Letters, 5(3), 829-835 (2014). PMC4103177

76. H. Matsuda, G.G. Putzel, V. Backman, I. Szleifer, “Macromolecular crowding as a regulator of gene transcription”, Biophysical Journal, 106, 1801-1810 (2014). PMC4008821

77. J. Yi, A.J. Radosevich, Y. Stypula, N. Mutyal, S.M. Azarin, E.L. Horcher, M. Goldberg, L. Bianchi, S. Bajaj, H.K. Roy, V. Backman, “Spatially-resolved optical and ultra-structural properties of colorectal and pancreatic field carcinogenesis observed by inverse spectroscopic optical coherence tomography”, JBO, 19(3), 036013 (2014). PMC4019430

78. L. Cherkezyan, Y. Stypula-Cyrus, H. Subramanian, C. White, M. Dela Cruz, R.K. Wali, M.J. Goldberg, L.K. Bianchi, H.K. Roy, V. Backman, “Nanoscale changes in chromatin organization represent the initial steps of tumorigenesis: a transmission electron microscopy study”, Biomed Central Cancer, 14(189), (2014). PMC3995586

79. A. Gomes, V. Backman, “Monte Carlo model of the depolarization of backscattered linearly polarized light in the sub-diffusion regime”, Optics Express, 22(5), 5325-5340 (2014).

80. K. Phillips, D. Damania, H. Subramanian, V. Backman, E. Anderson, M.H. Wong, O. McCarty, “Network signatures of nuclear and cytoplasmic density alterations in a model of pre- and post-metastatic colorectal cancer”, JBO, 19(1), 016016 (2014). PMC4019418

81. J.D. Rogers, A.J. Radosevich, J. Yi, V. Backman, “Modeling light scattering in tissue as continuous random media using a versatile refractive index correlation function”, IEEE JSTQE, 20(02) 7000514 (2013). PMC4289622

82. J. Chandler, H. Subramanian, C.D. Maneval, C.A. White, V. Backman, “High-speed spectral nanocytology for early cancer screening”, J. Biomedical Optics, 18(11), 117002 (2013). PMC3817856

83. V. Konda, L. Cherkezyan, H. Subramanian, K. Wroblewski, D. Damania, V. Becker, M. Goldberg, J. Chennat, L. Karl, M. Ferguson, I. Waxman, H. Roy, V. Backman, “Nanoscale

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markers of esophageal field carcinogenesis: potential implications for esophageal cancer screening”, Endoscopy, 45, 983-988, (2013). PMC4195538.

84. S. Ruderman, S. Mueller, A. Gomes, J. Rogers, V. Backman, “Method of detecting tissue contact for fiber-optic probes to automate data acquisition without hardware modification”, Biomedical Optics Express, 4(8), 1401-1412 (2013). PMC3756576.

85. J. Yi, Q. Wei, W. Liu, V. Backman, H. Zhang, “Visible-light optical coherence tomography for retinal oximetry”, Optics Letters, 38(11), 1796-1798 (2013). PMC3986589

86. H.K. Roy, D.P. Damania, M. DelaCruz, D.P. Kunte, H. Subramanian, S.E.Crawford, A.K. Tiwari, R.K. Wali, V. Backman, “Nano-architectural alterations in mucus layer fecal colonocytes in field carcinogenesis: potential for screening”, Cancer Prevention Research, 6, 1111-1119 (2013). PMC387374.

87. A.J. Radosevich, N.N. Mutyal, J. Yi, Y. Stypula-Cyrus, J.D. Rogers, M.J. Goldberg, L.K. Bianchi, S. Bajaj, H.K. Roy, V. Backman, “Ultrastructural alterations in field carcinogenesis measured by enhanced backscattering spectroscopy”, JBO, 18(9), 0970021-09700211 (2013). PMC3764252.

88. I.R. Capoglu, J.D. Rogers, A. Taflove, V. Backman, “The microscope in a computer: Image synthesis from three-dimensional full-vector solutions of Maxwell’s equations at the nanometer scale”, Progress in Optics, 57, 1-91 (2013).

89. T. Tan, A. Taflove, V. Backman, “Single realization stochastic FDTD for weak scattering waves in biological random media”, IEEE Trans. Ant. Prop., 61(2), 818-828 (2013). PMC4856227.

90. I. Capoglu, A. Taflove, V. Backman, “Computation of tightly-focused laser beams in the FDTD method”, Optics Express, 21(1), 87-101 (2013). PMC3636759.

91. I. Avital, R.C. Langan, T.A. Summers, S.R. Steele, S.A. Waldman, V. Backman, J. Yee, A. Nissan, P. Young, C. Womeldorph, P. Mancuso, R. Mueller, K. Noto, W. Grundfest, A.J. Bilchik, Mladjan Protic, M. Daumer, J. Eberhardt, Y.G. Man, B. LDM Brucher, A. Stojadinovic “Evidence-based guidelines for precision risk stratification-based screening (PRSBS) for colorectal cancer: lessons learned from the US armed forces: consensus and future directions”, Journal of Cancer, 4(3), 172-192 (2013). PMC3584831.

92. V. Backman, H.K. Roy, “Advances in biophotonics detection of field carcinogenesis for colon cancer risk stratification”, Journal of Cancer, 4(3), 251-261 (2013) (Special issue, invited paper). PMC3584838

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93. J. Yi, A.J. Radosevich, J.D. Rogers, S.C.P. Norris, I.R. Capoglu, A. Taflove, V. Backman, “Can OCT be sensitive to nanoscale structural alterations in biological tissue?”, Optics Express, 21(7) 9043–9059 (2013). PMC3641881.

94. N.N. Mutyal, A. Radosevich, A. Tiwari, Y. Stypula, R. Wali, V. Turzhitsky, J.D. Rogers, H.K. Roy ,V. Backman, “Biological mechanisms underlying structural changes induced by colorectal field carcinogenesis measured with Low-Coherence Enhanced Backscattering Spectroscopy (LEBS)”, PLoS One, 8(2), e57206 (2013). PMC3576387.

95. A. Gomes, V. Backman, “An algorithm for automated selection of application-specific fiber-optic reflectance probes”, J. Biomedical Optics, 18(2), 0270121-02701212 (2013). PMC3585420.

96. D. Damania, H.K. Roy, D. Kunte, J.A. Hurteau, H. Subramanian, L. Cherkezyan, M. Shah, N. Krosnjar, V. Backman, “Insights into the field carcinogenesis of ovarian cancer based on the nanocytology of endocervical and endometrial epithelial cancer cells” International Journal of Cancer, 133(5), 1143-1152 (2013). PMC3695064.

97. L.A. Marcelino, M.W. Westneat, V. Stoyneva, J. Henss, J.D. Rogers, A. Radosevich, V. Turzhitsky, M. Siple, A. Fang, T.D. Swain, J. Fung, V. Backman, “Modulation of light-enhancement to symbiotic algae by light-scattering in corals and evolutionary trends in bleaching”, PLoS One, 8(4) e61492 (2013). PMC3632607.

98. The Physical Sciences-Oncology Centers Network. “A physical sciences network characterization of non-tumorigenic and metastatic cells”. Sci. Rep. 3, 1449; DOI:10.1038/srep01449 (2013). PMC3636513.

99. Y. Stypula-Cyrus, D. Damania, D.P. Kunte, M. De La Cruz, H. Subramanian, H.K. Roy, V. Backman, “HDAC up-regulation in early colon field carcinogenesis is involved in cell tumorigenicity through regulation of chromatin structure”, PLoS One, 8(5): e64600 (2013). PMC3665824.

100. L. Cherkezyan, I. Capoglu, H. Subramanian, J.D. Rogers, D. Damania, A. Taflove, V. Backman, “Interferometric spectroscopy of scattered light can quantify the statistics of subdifractional refractive-index fluctuations”, PRL, 111, 033903 (2013). PMC4123763.

101. A.J. Gomes, V. Backman, “Analytical light reflectance models for overlapping-illumination and collection area geometries”, Applied Optics, 51(33), 8013-8021 (2012). PMC3655705.

102. H.K. Roy, V. Backman, “Spectroscopic applications in gastrointestinal endoscopy”, Clinical Gastroenterology and Hepatology, 10(12), 1335-1341 (2012). PMC3756813.

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103. A.J. Radosevich, J. Yi, J.D. Rogers, V. Backman, “Structural length-scale sensitivities of diffuse reflectance in continuous random media under the Born approximation”, Optics Letters, 37(24), 5220-5222 (2012). PMC3655697.

104. A. Radosevich, J.D. Rogers, I. Capoglu, N. Mutyal, P. Pradhan, V. Backman, “Open source software for electric field Monte Carlo simulation of coherent backscattering in biological media containing birefringence”, J. Biomedical Optics, 17(11), 115001-1 – 115001-13 (2012). PMC3487050.

105. J. Yi, V. Backman, “Imaging a full set of optical scattering properties of biological tissue by inverse spectroscopic optical coherence tomography”, Optics Letters, 37(21), 4443-4445 (2012). PMC3640644.

106. N. Mutyal, A. Radosevich, B. Gould, J.D. Rogers, A. Gomes, V. Turzhitsky, V. Backman, “A fiber optic probe design to measure depth-limited optical properties in vivo with Low-coherence Enhanced Backscattering (LEBS) Spectroscopy”, Optics Express, 20(18), 19643-19657 (2012). PMC3635466.

107. S.D. Strasser, G. Shekhawat, J.D. Rogers, V.P. Dravid, A. Taflove, V. Backman, “Near-field penetrating optical microscopy: A live cell nanoscale refractive index measurement technique for quantification of internal macromolecular density”, Optics Letters, 37(4), 506-508 (2012), PMC3357211.

108. A.J. Gomes, S. Ruderman, M. DelaCruz, R.K. Wali, H.K. Roy, V. Backman, “Errata: in vivo measurement of the shape of the tissue refractive index correlation function and its application to detection of colorectal field carcinogenesis”, J. Biomedical Optics, 17(4), 470051-470058 (2012). PMC3382344.

109. D. Damania, H.K. Roy, H. Subramanian, M.J. Goldberg, D.S. Weinberg, J. Muldoon, L. Cherkezyan, Y. Zhu, L.K. Bianchi, D. Shah, P. Pradhan, M. Borkar, H. Lynch, V. Backman, “Nanocytology of rectal colonocytes to assess risk of colon cancer based on field cancerization”, Cancer Research, 72(11), 2720-2727 (2012). PMC3557939.

110. J. Yi, Q. Wei, H.F. Zhang, V. Backman, “Structured interference optical coherence tomography”, Optics Letters, 37(15), 3048-3050 (2012). PMC3544536.

111. A.J. Radosevich, J.D. Rogers, V. Turzhitsky, N.N. Mutyal, J. Yi, H.K. Roy, V. Backman, “Polarized Enhanced Backscattering Spectroscopy for Characterization of Biological Tissues at Subdiffusion Length-scales”, IEEE JSTQE, 18(4) 1313-1325 (2012) (invited paper). PMC3806115.

112. L. Cherkezyan, H. Subramanian, V. Stoyneva, J. Rogers, S. Yang, D. Damania, A. Taflove, V. Backman, “Targeted alteration of real and imaginary refractive index of biological cells by histological staining”, Optics Letters, 37(10), 1601-1603 (2012), PMC3367326.

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113. I.R. Capoglu, A. Taflove, V. Backman, “A Frequency-Domain Near-Field-to-Far-Field Transform for Planar Layered Media”, IEEE Trans. of Antennas and Propagation, 60(4), 1878-1885 (2012).

114. D.P. Kunte, M. De La Cruz, R.K. Wali, Y. Stypula, A.K. Tiwari, J. Brasky, T. Gibson, P. Subramaniyan, A. Menon, V. Backman, H.K. Roy, “Dysregulation of MicroRNAs in Early Colon Carcinogenesis: Implications for Screening”, PLoS One, (9)7, e45591 (2012). PMC3458063.

115. A.J. Gomes, V. Turzhitsky, S. Ruderman, V. Backman, “Monte Carlo Model of the Penetration Depth for Polarization Gating Spectroscopy: Influence of Illumination-Collection Geometry and Sample Optical Properties”, J. Biomedical Optics, 51(20), 4627-4637 (2012). PMC3557942.

116. A. Radosevich, N. Mutyal, V. Turzhitsky, J. Rogers, J. Yi, A. Taflove, V. Backman, “Measurement of the spatial backscattering impulse-response at short length-scales with polarized enhanced backscattering (EBS)”, Optics Letters, 36(24), 4737-4739 (2011), PMC3355761.

117. V. Backman, H.K. Roy, “Light-scattering Technologies for Field Carcinogenesis Detection: A Modality for Endoscopic Pre-screening”, Gastroenterology, 140(1), 35-41 (2011). PMC3319699.

118. H.K. Roy, M.J. Goldberg, S. Bajaj, V. Backman, “Colonoscopic Optical Biopsy: Bridging Technological Advances to Clinical Practice”, Gastroenterology, 140(7), 1863–1880 (2011) (invited editorial, cover article). PMC3557924.

119. H.K. Roy, T. Hensing, V. Backman, “Nanocytology for field carcinogenesis detection: novel paradigm for lung cancer risk stratification”, Future Oncology, 7(11), 1-3 (2011) (editorial). PMC4123752

120. J.S. Kim, P. Pradhan, V. Backman, I. Szleifer, “Influence of chromosome density variations on the increase in nuclear disorder strength in carcinogenesis”, Physical Biology, 8(1), 015004, 1-6 (2011).

121. P. Pradhan, D. Damania, H. Joshi, V. Turzhitsky, H. Subramanian, H.K. Roy, A. Taflove, V. Dravid, V. Backman, “Quantification of Nanoscale Density Fluctuations by Electron Microscopy: probing cellular alterations in early carcinogenesis”, Physical Biology, 8, 026012, 1-9 (2011), PMC3332100.

122. S. Yang, A. Taflove, V. Backman, “Experimental Confirmation at Visible Light Wavelengths of the Giant Backscattering Perturbation Phenomenon of the Photonic Nanojet”, Optics Express, 19(8), 7074-7093 (2011), PMC3320766.

123. S.R. Gandhi, A.K. Tiwari, D.P. Kunte, M.A. De La Cruz, Y. Stypula, T. Gibson, J. Brasky, V. Backman, R.K. Wali, H.K. Roy, “Association of stem-like cells in gender-specific chemoprevention against intestinal neoplasia in MIN mouse”, Oncology Reports, 26(5), 1127-1132 (2011). PMC3557947.

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124. J.D. Rogers, V. Stoyneva, V. Turzhitsky, N. Mutyal, P. Pradhan, I.R. Capoglu, V. Backman, “An alternate formulation of enhanced backscattering as phase conjugation and diffraction: derivation and experimental observation”, Optics Express, 19(13), 11922-11931 (2011), PMC3319707.

125. I.R. Capoglu, C.A. White, J.D. Rogers, A. Taflove, V. Backman, “Numerical Simulation of Partially-Coherent Broadband Optical Imaging Using the FDTD Method”, Optics Letters, 36(9), 1596-1598 (2011), PMC3319708.

126. J.S. Kim, V. Backman, I. Szleifer, “Crowding-induced structural alterations of random-loop chromosome model”, Phys. Rev. Lett., 106, 168102, 1-4 (2011).

127. A.K. Tiwari, S.E. Crawford, A. Radosevich, R. Wali, Y. Stypula, D.P. Kunte, N. Mutyal, S. Ruderman, A. Gomes, M.L. Cornwell, M. De La Cruz, J. Brasky, T. Ward, V. Backman, H. K. Roy, “Neo-Angiogenesis and the Premalignant Micro-Circulatory Augmentation of Early Colon Carcinogenesis”, Cancer Letters, 306, 205–213 (2011). PMC3569093.

128. V. Turzhitsky, A. J. Radosevich, N. N. Mutyal, J. D. Rogers, V. Backman, “Measurement of Optical Scattering Properties with Low-Coherence Enhanced Backscattering Spectroscopy”, JBO, 16(6), 067007, 1-14 (2011), PMC3138801.

129. V. Turzhitsky, N.N. Mutyal, A.J. Radosevich, V. Backman, “Multiple Scattering Model for the Penetration Depth of Low-coherence Enhanced Backscattering”, JBO, 16(9), 097006, 1-5 (2011) PMC3188644.

130. H.K. Roy, H. Subramanian, D. Damania, T. Hensing, D. Ray, A. Bogojevic, P. Pradhan, J. Rogers, N. Hasabou, I. Capoglu, V. Backman, “Optical Detection of Buccal Epithelial Nano-Architectural Alterations in Patients Harboring Lung Cancer: Implications for Screening”, Cancer Research, 70(20), 7748-7754 (2010). PMC3703950.

131. V. Turzhitsky, J.D. Rogers, N.N. Mutyal, H.K. Roy, V. Backman, “Characterization of light transport in scattering media at sub-diffusion length scales with Low-coherence Enhanced Backscattering”, IEEE JSTQE, 16(3), 619-626 (2010). PMC2964859.

132. N.N. Boustany, S.A. Boppart, V. Backman, “Microscopic Imaging and Spectroscopy with Scattered Light”, Annual Review of Biomedical Engineering, 12, 285–314 (2010). PMC3357207.

133. H.K. Roy, A.J. Gomes, S. Ruderman, V. Turzhitsky, J.D. Rogers, V. Stoyneva, L.K. Bianchi, M.J. Goldberg, Y.L. Kim, E. Yen, A. Kromine, M. Jameel, V. Backman, “Optical Measurement of Rectal Microvasculature as an Adjunct to Flexible Sigmoidosocopy: Gender-Specific Implications”, Cancer Prevention Research, 3(7), 844–851 (2010). PMC3418881.

134. D. Damania, H. Subramanian, A.K. Tiwari, Y. Stypula, D. Kunte, P. Pradhan, H.K. Roy, V. Backman, “Role of cytoskeleton in controlling the disorder strength of cellular nanoscale architecture”, Biophys. J., 99, 989–996 (2010), PMC2913198.

135. S. Ruderman, A.J. Gomes, V. Stoyneva, J.D. Rogers, A.J. Fought, B.D. Jovanovic, V. Backman, “Analysis of pressure, angle and temporal effects on tissue optical properties

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from polarization-gated spectroscopic probe measurements”, Biomedical Optics Express, 1(2), 489-499 (2010), PMC3017986.

136. V. Turzhitsky, A. Radosevich, J.D. Rogers, A. Taflove, V. Backman, “A Predictive Model of Backscattering at Subdiffusion Length Scales”, Biomedical Optics Express, 1(3), 1034-1046 (2010), PMC3018048.

137. A.J. Radosevich, V. Turzhitsky, N.N. Mutyal, J.D. Rogers, V. Stoyneva, A.K. Tiwari, H.K. Roy, V. Backman, “Depth-resolved measurement of mucosal microvascular blood content using Low-coherence Enhanced Backscattering Spectroscopy”, Biomedical Optics Express, 1(4), 1196-1208 (2010), PMC3018078.

138. P. Pradhan, D. Dhwanil, V. Turzhitsky, V. Backman, “Quantification of nanoscale density fluctuations using electron microscopy: Light-localization properties of biological cells”, Applied Physics Lett., 97, 243704, 1-3 (2010), PMC3017571.

139. H.K. Roy, V. Turzhitsky, Y. Kim, M.J. Goldberg, P. Watson, J.D. Rogers, A.J. Gomes, A. Kromine, R.E. Brand, M. Jameel, N. Hasabou, P. Pradhan, V. Backman, “Association between Rectal Optical Signatures and Colonic Neoplasia: Potential Applications for Screening”, Cancer Research, 69(10), 4476-4483 (2009), PMC2722930.

140. A.J. Gomes, H.K. Roy, V. Turzhitsky, Y. Kim, J.D. Rogers, M.J. Goldberg, A. Kromine, M. Jameel, V. Backman, “Rectal Mucosal Microvascular Blood Supply Increase is Associated with Colonic Neoplasia”, Clinical Cancer Research, 15(9), 3110-3117 (2009), PMC2745222.

141. H. Subramanian, H.K. Roy, P. Pradhan, M.J. Goldberg, R.E. Brand, C. Sturgis, T. Hensing, D. Ray, J.-S. Chang, J. Mohammed, V. Backman, “Nanoscale Cellular Changes in Field Carcinogenesis Detected by Partial Wave Spectroscopy”, Cancer Research, 69(13), 5357-5363 (2009), PMC2802178.

142. S.C. Kong, A. Taflove, V. Backman, “Quasi one-dimensional light beam generated by a graded-index microsphere”, Optics Express, 17(5), 3722-3731 (2009), PMC2701736.

143. V. Turzhitsky, Y. Liu, N. Hasabou, M. Goldberg, H.K. Roy, V. Backman, R. Brand, “Investigating Population Risk Factors of Pancreatic Cancer by Evaluation of Optical Markers in the Duodenal Mucosa”, Disease Markers, 25, 313-321 (2009) (invited paper), PMC2730822.

144. S.C. Kong, A.V. Sahakian, A. Taflove, V. Backman, “High-Density Optical Data Storage Enabled by the Photonic Nanojet from a Dielectric Microsphere”, JJAP, 48, 03A008, 1-3 (2009).

145. H. Subramanian, P. Pradhan, Y. Liu, I. Capoglu, J. Rogers, H. Roy, R. Brand, V. Backman, “Partial wave microscopic spectroscopy detects sub-wavelength refractive index fluctuations: an application to cancer diagnosis”, Optics Letters, 34(4), 518-520 (2009), PMC2701738.

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146. J.D. Rogers, I.R. Capoglu, V. Backman, “Nonscalar elastic light scattering from continuous random media in the Born approximation”, Optics Letters, 34(12) 1891-1893 (2009). PMC19529738.

147. A. Heifetz, S.-C. Kong, A. V. Sahakian, A. Taflove, V. Backman, “Photonic Nanojets”, J. Computational and Theoretical Nanoscience, 6(9), 1979-1992 (2009) (invited paper). PMC2782642.

148. I. Capoglu, J. Rogers, A. Taflove, V. Backman, “Accuracy of the Born Approximation in Calculating the Scattering Coefficient of Biological Continuous Random Media”, Optics Letters, 34(17), 2679-2681 (2009). PMC19724530.

149. H. Subramanian, P. Pradhan, Y. Liu, I. Capoglu, X. Li, J. Rogers, A. Heiftez, D. Kunte, H.K. Roy, A. Taflove, V. Backman, “Optical Methodology for Detecting Histologically Unapparent Nanoscale Consequences of Genetic Alterations in Biological Cells”, PNAS, 105(51), 20124–20129 (2008). PMC2629261.

150. H.K. Roy, A. Gomes, V. Turzhitsky, M.J. Goldberg, J. Rogers, S. Ruderman, Y.L. Kim, A. Kromine, R.E. Brand, M. Jameel, N. Hasabou, V. Backman, “Spectroscopic Microvascular Blood Detection from the Endoscopically Normal Colonic Mucosa: Biomarker for Neoplasia Risk”, Gastroenterology, 135(4), 1069-1078 (2008) (cover article). PMC3405534.

151. S. C. Kong, A. V. Sahakian, A. Heifetz, A. Taflove, V. Backman, “Robust Detection of Deeply Subwavelength Pits in Simulated Optical Data-Storage Disks Using Photonic Jets”, Applied Physics Letters, 92(21), 211102, 1-3 (2008), (cover article).

152. V. Turzhitsky, A.J. Gomes, Y.L. Kim, Y. Liu, A. Kromine, J.D. Rogers, M. Jameel, H.K. Roy, V. Backman, “Measuring Mucosal Blood Supply in vivo with a Polarization Gating Probe”, Applied Optics, 47(32), 6046-6057 (2008). PMC2728617.

153. S.C. Kong, A.V. Sahakian, A. Taflove, V. Backman, “Photonic Nanojet-enabled Optical Data Storage”, Optics Express, 16(18), 13713-13719 (2008).

154. H.K. Roy, V. Turzhitsky, Y.L. Kim, Y. Liu, M.J. Goldberg, R.E. Brand, N. Hasabou, M. Jameel, V. Backman, “Spectral Slope from the Endoscopically-Normal Mucosa Predicts Concurrent Colonic Neoplasia: A Pilot Ex-Vivo Clinical Study”, Diseases of Colon and Rectum, 51, 1381–1386 (2008), PMC2913285.

155. S.C. Kong, J.J. Simpson, A. Taflove, Vadim Backman, “ADE-FDTD Scattered-Field Formulation for Dispersive Materials”, IEEE Microwave and Wireless Components Letters, 18(1), 4-6 (2008), PMC2763393.

156. C. Mujat, C. Greiner, A. Baldwin, F. Tian, J.M. Levitt, L.A. Stucenski, M. Hunter, Y.L. Kim, V. Backman, M. Feld, K. Münger, I. Georgakoudi, “Endogenous optical biomarkers of normal and human papillomavirus immortalized epithelial cells”, International Journal of Cancer, 122(2), 363-371 (2008).

157. I.R. Capoglu, A. Taflove, V. Backman, “Generation of an incident focused light pulse in FDTD”, Optics Express, 16(23), 19208-19220 (2008), PMC2743158.

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158. Y. Liu, R.E. Brand, V. Turzhitsky, Y.L. Kim, H.K. Roy, N. Hasabou, C. Sturgis, D. Shah, C. Hall, V. Backman, “Optical markers in duodenal mucosa predict the presence of pancreatic cancer”, Clinical Cancer Research, 13(15), 4392-4399 (2007), (feature article).

159. H. Subramanian, P. Pradhan, Y. Kim, V. Backman, ”Penetration depth of low-coherence enhanced backscattering of light in sub-diffusion regime”, Phys. Rev. E, 75, 041914, 1-9 (2007).

160. X. Li, A. Taflove, V. Backman, “Anomalous Oscillations in the Spectra of Light Backscattered by Inhomogeneous Microparticles”, Phys. Rev. E, 75, 037601, 1-4 (2007).

161. J. Allen, Y. Liu, Y.L. Kim, V.M. Turzhitsky, V. Backman, G.A. Ameer, “Spectroscopic translation of cell–material interactions”, Biomaterials, 28, 162–174 (2007).

162. R. Figueiredo, V. Backman, Y. Liu, J. Paladugula, “Architecture and Performance of a Grid-enabled Lookup-based Biomedical Optimization Application: Light Scattering Spectroscopy”, IEEE Transactions on Information Technology in BioMedicine, 11(2), 170-178 (2007).

163. A. Kaushiva, V.M Turzhitsky, V. Backman, G.A. Ameer, “A biodegradable vascularizing membrane: A feasibility study”, Acta Biomaterialia, 3 (5), 631-642 (2007).

164. H.K. Roy, R.K. Wali, Y. Kim, Y. Liu, J. Hart, D.P. Kunte, J.L. Koetsier, M.J. Goldberg, V. Backman, “Inducible Nitric Oxide Synthase (iNOS) Mediates the Early Increase of Blood Supply (EIBS) in Colon Carcinogenesis”, FEBS, 581 (20), 3857-3862 (2007), PMC2913280.

165. A. Heifetz, A. Taflove, V. Backman, “Subdiffraction optical resolution of a gold nanosphere located within the nanojet of a Mie-resonant dielectric microsphere”, Optics Express, 15 (25), 17334-17342 (2007).

166. Y.L. Kim, Y. Liu, P. Pradhan, X. Li, V. Backman, "Origin of low-coherence enhanced backscattering”, Optics Letters, 31(10), 1459-1461 (2006).

167. H.K. Roy, Y.L. Kim, Y. Liu, R.K. Wali, M.J. Goldberg, V. Turhitsky, J. Horwitz, V. Backman, “Risk Stratification of Colon Carcinogenesis through Enhanced Backscattering Spectroscopy Analysis of the Uninvolved Colonic Mucosa”, Clinical Cancer Research, 19(3), 961-968 (2006).

168. Z. Chen, X. Li, A. Taflove, V. Backman, “Super-enhanced Backscattering of Light by Nanoparticles”, Optics Letters, 31(2), 196-198 (2006).

169. M.P. Siegel, Y.L. Kim, H. Roy, R. Wali, V. Backman, “Assessment of Blood Supply in Superficial Tissue using Polarization-Gated Elastic Light-Scattering Spectroscopy”, Applied Optics, 40(2), 335-342 (2006).

170. Z. Chen, A. Taflove, V. Backman, “Highly Efficient Optical Coupling and Transport Phenomena in Chains of Dielectric Microspheres”, Optics Letters, 31(3), 389-391 (2006).

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171. Z. Chen, X. Li, A. Taflove, V. Backman, “Backscattering Enhancement of Light by Nanoparticles Positioned in Localized Optical Intensity Peaks”, Applied Optics, 45(4), 633-638 (2006).

172. S. Tseng, A. Taflove, D. Maitland, V. Backman, J.T. Walsh, “Extracting Geometrical Information of Closely Packed Random Media from Multiply Scattered Light via a Cross-correlation Analysis”, IEEE Antenna and Wireless Propagation Letters, 5, 91-94 (2006).

173. J. Gong, B. Liu, Y. Kim, X. Li, V. Backman, “Optimal Spectral Reshaping for Resolution Improvement in Optical Coherence Tomography”, Optics Express, 14(13), 5909-5915 (2006).

174. S. Tseng, A. Taflove, D. Maitland, V. Backman, “Pseudospectral Time Domain Simulations of Multiple Light Scattering in Three-Dimensional Macroscopic Random Media”, Radio Science, 41, RS4009, doi:10.1029/2005RS003408 (2006).

175. H.K. Roy, D.P.Kunte, J.L. Koetsier , J. Hart, Y.L.Kim, Y. Liu, M. Bissonnette, M. Goldberg, V. Backman, R.K. Wali, “Chemoprevention of colon carcinogenesis by polyethylene glycol: suppression of epithelial proliferation via modulation of SNAIL/B-catenin signaling”, Molecular Cancer Therapeutics, 5(8), 2060-2069 (2006).

176. H. Subramanian, P. Pradhan, Y. Kim, Y. Liu, X. Li, V. Backman, “Modeling low-coherence enhanced backscattering using Monte Carlo simulation”, Applied Optics, 45(24), 6292-6300 (2006).

177. Y.L. Kim, V. Turzhitsky, Y. Liu, H.K. Roy, R.K. Wali, H. Subramanian, P. Pradhan, V. Backman “Low-coherence enhanced backscattering: review of principles and applications for colon cancer screening”, J. Biomed. Optics, 11(4), 041125-1-10 (2006).

178. Y.L. Kim, P. Pradhan, M.H. Kim, V. Backman, “Circular Polarization Memory Effect in Low-coherence Enhanced Backscattering of Light”, Optics Letters, 31, 2744-2746 (2006).

179. L.A. Marcelino, V. Backman, A. Donaldson, C. Steadman, J. Thompson, S. Pacocha-Preheim, C. Lien, E. Lim, D. Veneziano, M.F. Polz, “Accurately quantifying low-abundant targets amid similar sequences by revealing hidden correlations in oligonucleotide microarray data”, PNAS, 103(37), 13629-13634 (2006).

180. M. Hunter, V. Backman, G. Popescu, M. Kalashnikov, C.W. Boone, A. Wax, V. Gopal, K. Badizadegan, G.D. Stoner, M.S. Feld, “Tissue Self-Affinity and Polarized Light Scattering in the Born Approximation: A New Model for Precancer Detection”, Phys. Rev. Lett, 97(13), 138102, 1-4 (2006).

181. X. Xia, Y. Liu, V. Backman, G.A. Ameer, “Engineering sub-100 nm multi-layer nanoshells”, Nanotechnology, 17, 5435-5440 (2006).

182. H.K. Roy, V. Backman, M. Goldberg, “Colon Cancer Screening: The Good, the Bad and the Ugly”, Archives of Internal Medicine, 166, 2177-2179 (2006), (editorial).

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183. A. Heifetz, K. Huang, A.V. Sahakian, X. Li, A. Taflove, V. Backman, “Experimental Confirmation of Backscattering Enhancement Induced by a Photonic Jet”, App. Phys. Lett., 89, 221118, (2006).

184. Y.L. Kim, Y. Liu, V.M. Turzhitsky, R. Wali, H. Roy, V. Backman, “Depth-resolved Low-coherence Enhanced Backscattering”, Optics Letters, 30(7), 741-743 (2005).

185. Y.L. Kim, Y. Liu, R.K. Wali, H.K. Roy, V. Backman, “Low-Coherent Backscattering Spectroscopy for Tissue Characterization”, Applied Optics, 44(3), 366-377 (2005).

186. X. Li, A. Taflove, V. Backman, “Quantitative Analysis of Depolarization of Backscattered Light by Stochastically Inhomogeneous Dielectric Particles”, Optics Letters, 30(8), 902-904 (2005).

187. H.K. Roy, Y. Kim, R.K. Wali, Y. Liu, J. Koetsier, A. Kromine, D.P. Kunte, M.J. Goldberg, V. Backman, “Spectral Markers in Preneoplastic Intestinal Mucosa: An Accurate Predictor of Tumor Risk in the MIN Mouse”, Cancer Epidemiology, Biomarkers & Prevention, 14(7), 1639-1645 (2005), (cover article).

188. K. Chen, Y. Kim, A. Taflove, V. Backman, “Self-Assembled Patterns of Nanospheres with Symmetries from Submicrons to Centimeters”, Applied Physics Letters, 86, 033101, 1-3 (2005), (cover article).

189. R.K. Wali, H.K. Roy, Y.L. Kim, Y. Liu, J.L. Koetsier, D.P. Kunte, M.J. Goldberg, V. Turzhitsky, V. Backman, “Increased Microvascular Blood Content is an Early Event in Colon Carcinogenesis”, Gut, 54, 654-660 (2005).

190. K. Chen, Y. Liu, G. Ameer, V. Backman, “Optimal Design of Structured Nanospheres for Ultrasharp Light-Scattering Resonances as Molecular Imaging Multilabels”, J. Biomedical Optics, 10(2), 024005, 1-6 (2005).

191. X. Li, A. Taflove, V. Backman, “Modified FDTD Near-to-Far Field Transformation for Improved Backscattering Calculation of Strongly Forward-Scattering Objects”, IEEE Antennas and Wireless Propagation Lett., 4, 35-38 (2005).

192. Y. Liu, Y. Kim, V. Backman, “Development of a Bioengineered Tissue Model and Its Application in the Investigation of the Depth Selectivity of Polarization Gating”, Applied Optics, 44(12) 2288-2299 (2005).

193. X. Li, Z. Chen, A. Taflove, V. Backman, “Optical Analysis of Nanoparticles via Enhanced Backscattering Facilitated by 3-D Photonic Nanojets”, Optics Express, 13(2), 526-533 (2005).

194. Y. Liu, Y. Kim, X. Li, V. Backman, “Investigation of Depth Selectivity of Polarization Gating for Tissue Characterization”, Optics Express, 13(2), 601-611 (2005).

195. S.H. Tseng, Y.L. Kim, A. Taflove, D. Maitland, V. Backman, J.T. Walsh, Jr., “Simulation of Enhanced Backscattering of Light by Numerically Solving Maxwell’s Equations without Heuristic Approximations", Optics Express, 13(10), 3666-3672 (2005).

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196. S.H. Tseng, J.H. Greene, A. Taflove, D. Maitland, V. Backman, J.T. Walsh, “Exact Solution of Maxwell's Equations for Optical Interactions with a Macroscopic Random Medium: Addendum”, Optics Letters, 30(1), 56-57 (2005).

197. Y. Liu, X. Li, Y.L. Kim, V. Backman, “Elastic Backscattering Spectroscopic Microscopy”, Optics Letters, 30(18), 2445-2447 (2005).

198. S.H. Tseng, A. Taflove, D. Maitland, V. Backman, J.T. Walsh, Jr., “Investigation of the Noise-like Structures of the Total Scattering Cross-section for Random Media”, Optics Express, 13(16), 6127-6132 (2005).

199. X. Li, A. Taflove, V. Backman, “Recent Progress in Exact and Reduced-order Modeling of Light-scattering Properties of Complex Structures”, IEEE JSTQE, 11(4), 759-765 (2005).

200. H.K. Roy, Y. Liu, R. Wali, Y.L. Kim, A.K. Kromine, M.J. Goldberg, V. Backman, “Four-Dimensional Elastic Light-Scattering Fingerprints as Preneoplastic Markers in the Rat Model of Colon Carcinogenesis”, Gastroenterology, 126, 1071-1081 (2004) (feature article).

201. X. Li, Z. Chen, A. Taflove, V. Backman, “Equiphase-sphere Approximation for Light Scattering by Stochastically Inhomogeneous Microparticles”, Phys. Rev. E, 70, 056610, 1-8 (2004).

202. X. Li, Z. Chen, J. Gong, A. Taflove, V. Backman, “Analytical Techniques for Addressing Forward and Inverse Problems of Light Scattering by Irregularly Shaped Particles”, Optics Letters, 29 (11), 1239-1241 (2004).

203. Z. Chen, A. Taflove, V. Backman, “Concept of the Equiphase Sphere for Light Scattering by Nonspherical Dielectric Particles”, JOSA A, 21(1), 88-97 (2004).

204. S.H. Tseng, A. Taflove, D. Maitland, V. Backman, J.T. Walsh, Jr., “Exact Solution of Maxwell’s Equations for Optical Interactions with a Macroscopic Random Medium”, Optics Letters, 29 (12), 1393-1395 (2004).

205. Y.L. Kim, Y. Liu, H.K. Roy, R.K. Wali, V. Backman, “Coherent Backscattering Spectroscopy”, Optics Letters, 29(16), 1906-1908 (2004).

206. X. Li, Z. Chen, A. Taflove, V. Backman, “Equiphase-sphere approximation for analysis of light scattering by arbitrarily-shaped nonspherical particles”, Applied Optics, 43(23), 4497-4505 (2004).

207. Z. Chen, A. Taflove, V. Backman, “Photonic Nanojet Enhancement of Backscattering of Light by Nanoparticles: a Potential Novel Visible-Light Ultramicroscopy Technique”, Optics Express, 12 (7), 1214-1220 (2004).

208. H.K. Roy, P. Iversen, J. Hart, Y. Liu, J.L. Koetsier, Y. Kim, D.P. Kunte, M. Madugula, V. Backman, R.K. Wali, “Downregulation of SNAIL Suppresses MIN Mouse Tumorigenesis: Modulation of Apoptosis, Proliferation and Fractal Dimension”, Molecular Cancer Therapeutics, 3(9), 1159-1165 (2004).

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209. Z. Chen, A. Taflove, V. Backman, “Equivalent Volume-Averaged Light Scattering Behavior of Randomly Inhomogeneous Dielectric Spheres in the Resonant Range”, Optics Letters, 28 (10), 765-767 (2003).

210. Y.L. Kim, Y. Liu, R.K. Wali, H.K. Roy, M.J. Goldberg, A.K. Kromine, K. Chen, V. Backman, “Simultaneous Measurement of Angular and Spectral Properties of Light Scattering for Characterization of Tissue Microarchitecture and its Alteration in Early Precancer”, IEEE J Sel Top Quant Elect , 9(2), 243-257 (2003).

211. K. Chen, A. Kromine, Y.L. Kim, M.P. Ulmer, B.W. Wessels, V. Backman, “Nanoparticle Sizing with a Resolution Beyond the Diffraction Limit Using UV Light Scattering Spectroscopy”, Optics Communications, 228, 1-7 (2003).

212. K. Badizadegan, V. Backman, C.W. Boone, C.P. Crum, R.R. Dasari, I. Georgakoudi, K. Keefe, K. Munger, S.M. Shapshay, E.E. Sheetse, M.S. Feld, “Spectroscopic Diagnosis and Imaging of Invisible Pre-cancer”, Faraday Discuss., 126, 265–279 (2004).

213. M.G. Muller, T.A. Valdez, I. Georgakoudi, V. Backman, C. Fuentes, S. Kabani, N.Laver, Z.M. Wang, C.W. Boone, R.R. Dasari, S.M. Shapshay, M.S. Feld, “Spectroscopic Detection and Evaluation of Morphologic and Biochemical Changes in Early Human Oral Carcinoma”, Cancer, 97, 1681-1692 (2003).

214. I. Georgakoudi, E.E. Sheets, M.G. Muller, V. Backman, C.P. Crum, K. Badizadegan, R.R. Dasari, M.S. Feld, “Trimodal Spectroscopy for the Detection and Characterization of Cervical Precancers in vivo”, Am. J. Obstet. Gynaecol., 186, 374-382 (2002).

215. A.Wax, C. Yang, V. Backman, M. Kalashnikov, R.R. Dasari, M.S. Feld, “Determination of Particle Size Using the Angular Distribution of Backscattered Light as Measured with Low-coherence Interferometry”, JOSA, 19, 737-744 (2002).

216. A.Wax, C. Yang, V. Backman , K. Badizadegan, C.W. Boone, R.R. Dasari, M.S. Feld, “Cellular Oganization and Substructure Measured Using Angle-Resolved Low-Coherence Interferometry”, Biophys. J, 82, 2256-2264 (2002).

217. V. Backman, L.T. Perelman, J.T. Arendt, R. Gurjar, M.G. Muller, Q. Zhang, G. Zonios, E. Kline, T. McGillican, T. Valdez, J. Van Dam, M. Wallace, K. Badizadegan, J.M. Crawford, M. Fitzmaurice, S. Kabani, H.S. Levin, M. Seiler, R.R.Dasari, I. Itzkan, M.S. Feld, “Light Scattering Spectroscopy: A New Technique for Clinical Diagnosis of Precancerous And Cancerous Changes in Human Epithelia”, Lasers in Life Sciences, 9, 255-263 (2001).

218. R. Gurjar, V. Backman, L.T. Perelman, I. Georgakoudi, K. Badizadegan, I. Itzkan, R. Dasari, M.S. Feld, “Imaging of Human Epithelial Properties with Polarized Light Scattering Spectroscopy”, Nature Medicine, 7, 1245-1248 (2001).

219. V. Backman, V. Gopal, M. Kalashnikov, K. Badizadegan, R. Gurjar, A. Wax, I. Georgakoudi, M. Mueller, C.W. Boone, R.R. Dasari, M.S. Feld, “Measuring Cellular Structure at Submicrometer Scale with Light Scattering Spectroscopy”, IEEE J. Sel. Top. Quant. Elect., 7, 887-894 (2001).

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220. K. Kneipp, L.T. Perelman, H. Kneipp, V. Backman, A. Jorio, G. Dresselhaus, M.S. Dresselhaus, “Coupling and Intensity Exchange Between Photon Modes Observed in Strongly Enhanced Raman Spectra of Single Wall Carbon Nanotubes on Silver Colloidal Clusters”, Phys. Rev. B, 6319, 3411 (2001).

221. I. Georgakoudi, B.C. Jacobson, J. Van Dam, V. Backman, M.B. Wallace, M.G. Muller, Q. Zhang, K. Badizadegan, D. Sun, G.A. Thomas, L.T. Perelman, M.S. Feld, “Fluorescence, Reflectance, and Light Scattering Spectroscopy for Evaluating Dysplasia in Patients with Barrett’s Esophagus”, Gastroenterology, 120, 1620-1629 (2001).

222. V. Backman, L.T. Perelman, J.T. Arendt, R. Gurjar, M.G. Muller, Q. Zhang, G. Zonios, E. Kline, T. McGillican, T. Valdez, J. Van Dam, M. Wallace, K. Badizadegan, J.M. Crawford, M. Fitzmaurice, S. Kabani, H.S. Levin, M. Seiler, R.R.Dasari, I. Itzkan, M.S. Feld, “Detection of Preinvasive Cancer Cells In Situ”, Nature, 406, 35-36 (2000).

223. M. Wallace, L.T. Perelman, V. Backman, J. Crawford, M. Fitzmaurice, M. Seiler, K. Badizadegan, S. Shields, I. Itzkan, R. Dasari, J. Van Dam, M.S. Feld, “Endoscopic Detection of Dysplasia in Patients with Barrett’s Esophagus Using Light Scattering Spectroscopy”, Gastroenterology, 119, 677-682 (2000).

224. V. Backman, R. Gurjar, K. Badizadegan, R. Dasari, I. Itzkan, L.T. Perelman, M.S. Feld, “Polarized Light Scattering Spectroscopy for Quantitative Measurement of Epithelial Cellular Structures In Situ ”, IEEE J. Sel. Top. Quant. Elect., 5, 1019-1026 (1999).

225. V. Backman, S.V. Bobashev, O.S. Vasyutinskii, “New Methods for Determining the Polarization State of Vacuum Ultraviolet Radiation”, Tech. Phys., 44, 1103-1110 (1999).

226. G. Zonios, L.T. Perelman, V. Backman, J. Van Dam, M.S. Feld, “Diffuse Reflectance Spectroscopy of Human Adenomatous Colon Polyps In Vivo”, Applied Optics, 38, 6628-6637 (1999).

227. L.T. Perelman, V. Backman, M. Wallace, G. Zonios, R. Manoharan,, A. Nusrat, S. Shields, M. Seiler, C. Lima, T. Hamano, I. Itzkan, J. Van Dam, J.M. Crawford, M.S. Feld, “Observation of Periodic Fine Structure in Reflectance from Biological Tissue: A New Technique for Measuring Nuclear Size Distribution”, Phys. Rev. Lett., 80, 627 (1998).

228. V. Backman, S.V. Bobashev, O.S. Vasyutinskii, “Determination of Polarization of Vacuum-Ultraviolet Radiation by Fluorescence and Probe-Beam Techniques”, Sol. Phys., 164, 397-401 (1996).

229. V. Backman, S.V. Bobashev, O.S. Vasyutinskii, “Dichroism of Probe Radiation Absorption in an Atomic Gas Excited by Synchrotron Radiation”, Tech. Phys. Lett., 20, 14-18 (1994).

B. Books and Book Chapters

1. Scott Gladstein, Andrew Stawarz, Luay M. Almassalha, Lusik Cherkezyan, John E. Chandler, Xiang Zhou, Hariharan Subramanian, and Vadim Backman, “Measuring Nanoscale Chromatin Heterogeneity with Partial Wave Spectroscopic Microscopy”, in

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Cellular Heterogeneity, Natasha S. Barteneva, Ivan A. Vorobjev, eds. Springer Protocols, 2018.

2. Vadim Backman, Adam Wax and Hao Zhang, “Biophotonics Laboratory Guide”, CRC Press, expected 2018.

3. Ilker R. Capoglu, Jeremy D. Rogers, Allen Taflove and Vadim Backman, “The Microscope in a Computer: Image Synthesis from Three-Dimensional Full-Vector Solutions of Maxwell’s Equations at the Nanometer Scale”, in Progress in Optics, Emil Wolf ed., Elsevier, 2012.

4. Ilker R. Capoglu, Jeremy Rogers, Snow H. Tseng, Kun Chen, Ming Ding, Allen Taflove, and Vadim Backman, “FDTD and PSTD Applications in Biophotonics”, Computational Electromagnetics, 2012.

5. J.D. Rogers, Y. Kim, V. Backman, “Enhanced Backscattering for Tissue Characterization”, in Biomedical Applications of Light Scattering, A. Wax, V. Backman eds, McGraw Hill Publishing, 2009.

6. A. Wax, V. Backman, “Overview of classical light scattering formalisms”, in Biomedical Applications of Light Scattering, A. Wax and V. Backman eds, McGraw Hill Publishing, 2009.

7. I. Capoglu, J. Rogers, V. Backman, “Light Scattering from Continuous Random Media”, in Biomedical Applications of Light Scattering, A. Wax and V. Backman eds, McGraw Hill Publishing, 2009.

8. S.H. Tseng, I.R. Capoglu, A. Taflove, V. Backman, “Modeling of Light Scattering By Biological Tissues Via Computational Solution of Maxwell’s Equations”, in Biomedical Applications of Light Scattering, A. Wax and V. Backman eds, McGraw Hill Publishing, 2009.

9. I. Georgakoudi, J.T. Motz, V. Backman, G. Angheloiu, A.S. Haka, M. Muller, R.D. Dasari, M.S. Feld, “Quantitative Characterization of Biological Tissue Using Optical Spectroscopy”, in Biomedical Photonics Handbook, Tuan Vo-Dinh ed., CRC Press, New York, 2003.

10. L.T. Perelman, V. Backman “Light Scattering Spectroscopy: Theory and Applications”, in Optical Biomedical Diagnostics, V. Tuchin, ed., SPIE Press, Bellingham, 2002.

11. A. Wax, V. Backman, C. Yang, M.S. Feld, “Light scattering spectroscopic techniques for examining cellular structure, organization and dynamics”, in “Biomedical Optical Engineering”, Fujimoto, ed., Oxford University Press, 2002.

12. V.Y. Backman, O.S. Vasyutinskii, “Interaction of Polarized Light with an Analyzer”, Ioffe Physico Technical Institute Press, St. Petersburg, Russia, 1996.

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C. Other Major Publications

1. A. Gomes, H.K. Roy, V. Turzhitsky, M.J. Goldberg, J. Rogers, S. Ruderman, Y.L. Kim, A. Kromine, R.E. Brand, M. Jameel, N. Hasabou, V. Backman, “Increased Microvascular Blood Supply as a Potential Biomarker of Field Carcinogenesis in the Colon”, The Journal: Robert H. Lurie Comprehensive Cancer Center Journal (2009).

2. H.K. Roy, R.K. Wali, Y. Liu, Y.L. Kim, M.J. Goldberg, V. Backman, “Four-Dimensional Elastic Light-Scattering Fingerprinting for Early Detection of Colon Carcinogenesis”, The Journal: Robert H. Lurie Comprehensive Cancer Center Journal, 9(2), 15-20 (2004).

3. K. Badizadegan, V. Backman, C.W. Boone, C.P. Crum, R.R. Dasari, I. Georgakoudi, K. Keefe, K. Munger, S.M. Shapshay, E.E. Sheets, M.S. Feld, “Spectroscopic Diagnosis and Imaging of Invisible Pre-Cancer”, 126th Faraday Discussion, Applications of Spectroscopy to Biomedical Problems (2003).

4. G. Popescu, C. Fang-Yen, L. Deflores, M. Chu, H. Iwai, M. Hunter, M. Kalashnikov, V. Backman, K. Badizadegan, C. Boone, G. Stoner, R. Dasari, M.S. Feld, “Seeing Small Biological Structures with Light”, Laser Spectroscopy, World Scientific Publishing Co. (2003).

5. V. Backman, R. Gurjar, L.T. Perelman, V. Gopal, M. Kalashnikov, K. Badizadegan, A. Wax, I. Georgakoudi, M. Mueller, C.W. Boone, I. Itzkan, R.R. Dasari, M.S. Feld, “Imaging and Measurement of Cell Structure and Organization with Submicron Accuracy Using Light Scattering Spectroscopy”, Optical Biopsy, 4613: 101-110 (2002).

6. L.T. Perelman, V. Backman, “Detection of Early Cancer and Precancer with Scattered Light”, Invited Internet Lecture, International School for Young Scientists and Students on Optics, Laser Physics & Biophysics (2000).

7. V. Backman, “Significant Breakthroughs in Early Cancer Detection”, The American Institute of Physics Bulletin of Physics News, 477, March 31, 2000.

8. V. Backman, R. Gurjar, K. Badizadegan, G. Zonios, I. Itzkan, R.R. Dasari, J.M. Crawford, J. Van Dam, L.T. Perelman, M.S. Feld, “Light Scattering Spectroscopy for Early Cancer Diagnosis”, Laser Spectroscopy, World Scientific Publishing Co., Rainer Blatt et al. ed., 286-295 (1999).

9. M. Wallace, L.T. Perelman, V. Backman, J.M. Crawford, M. Fitzmaurice, M. Seiler, K. Badizadegan, S. Shields, I. Itzkan, R.R. Dasari, J. Van Dam, M.S. Feld, “Research Report on Endoscopic Detection of Dysplasia in Patients With Barrrett’s Esophagus Using Light Scattering Spectroscopy: A Prospective Study,” Spectrograph, 15, 2 (1999).

CONFERENCE PRESENTATIONS

1. V. Backman, “Chromatin Regulation to Fight Resistance in Cancer Chemotherapy”, Illinois Ignite Conference, Rosemont, IL, September 27, 2018.

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2. V. Backman, “Bridging Chromatin Nanoimaging and Molecular Modeling: What Can We Learn About Chromatin Packing as a Regulator of Transcription?”, FASEB Conference on Transcription, Chromatin and Epigenetics, Florence, Italy, September 19, 2018.

3. V. Backman, “Bridging Chromatin Nanoimaging and Molecular Modeling: What Can We Learn About Chromatin Packing as a Regulator of Transcription?”, Telluride Workshop on Chromatin Structure and Dynamics, Telluride, CO, July 31, 2018.

4. V. Backman, “Design and Implementation of EFRI Projects” (Keynote), 2018 NSF EFRI Workshop: Convergence and Interdisciplinarity in Advancing Larger Scale Research, Alexandria, VA, May 14, 2018.

5. V. Backman, “Convergence of Nanoimaging and Biology: From Decoding Chromatin Packing to Cancer Diagnostics and Therapeutics”, H Foundation Basic Science Symposium, Chicago, IL, April 20, 2018.

6. V. Backman, “Convergence of Nanoimaging and Biology: Can Engineering Lead to a Cancer Cure?” OSA Biophotonics Congress, Hollywood, FL, April 6, 2018.

7. A. Eshein, Y. Li, X. Zhou, G. Spiver, T.Q. Nguyen, L. Almassalha, J. Chandler, S. Gladstein, B. Dong, C. Sun, H. Zhang, V. Backman, “Nanoscale Imaging of Chromatin with Labeled and Label-Free Super-Resolution Microscopy and Partial-Wave Spectroscopy”, OSA Biophotonics Congress, Hollywood, FL, April 4, 2018.

8. V. Backman, “Nanotechnology in Gastroenterology: Small Steps for Large Gains” (Keynote), AGA Tech Summit, Boston, MA, March 22, 2018

9. V. Backman, “Interferometric Spectroscopy of Scattered Light for the Quantification of Nanoscale Structure of Chromatin”, SPIE Photonics West, San Francisco, CA, January 30, 2018.

10. V. Backman, “What Optical Nanoscopy Reveals About the Structure of the Genome and its Role in Carcinogenesis”, SPIE Photonics West, San Francisco, CA, January 28, 2018.

11. B. Dong, B.T. Soetikno, Z. Chen, V. Backman, C. Sun, H.F. Zhang, “Three-Dimensional, Polarization-Sensitive, Spectroscopic Photon Localization Microscopy for Parallel Single-Molecules Imaging and Tracking”, SPIE Photonics West, San Francisco, CA, January 27, 2018.

12. A. Eid, D. Zhang, J. Winkelmann, J. Yi, V. Backman, “Validating Nanoscale Sensitivity of Spectroscopic OCT using FDTD”, SPIE Photonics West, San Francisco, CA, January 28, 2018.

13. J. Winkelmann, A. Eid, T.Q Nguyen, T. Bui, J. Yi, V. Backman, “In Vivo Imaging Using a Visible Inverse Spectroscopic Optical Coherence Tomography Probe”, SPIE Photonics West, San Francisco, CA, January 31, 2018.

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14. R. Liu, J. Winkelmann, G. Spicer, A. Eid, Y. Zhu, T.Q. Nguyen, G.A. Ameer, J. Yi, V. Backman, “In vivo Functional Microangiography with Sensitivity Down to the Capillary level by Dual Band Dual Scan Inverse Spectroscopic Optical Coherence Tomography (D2-ISOCT)”, SPIE Photonics West, San Francisco, CA, January 29, 2018.

15. Y. Li, B. Dong, A. Eshein, G. Spicer, W. Wu, L. Almassalha, R. Liu, T.Q. Nguyen, J. Chandler, C. Sun, H.F. Zhang, V. Backman, “Chromatin Structure Quantification from Super-Resolution Intrinsic Fluorescence Imaging”, SPIE Photonics West, San Francisco, CA, January 28, 2018.

16. G. Spicer, G.C. Bushnell, A. Eid, J. Winkelmann, R. Liu, J. Yi, S.M. Azirin, L.D. Shea, V. Backman, “Detection of Ultrastructural Modification in a Synthetic Pre-Metastatic Niche with Inverse Spectroscopic Optical Coherence Tomography (ISOCT)”, SPIE Photonics West, San Francisco, CA, January 31, 2018.

17. A Eshein, X. Zhou, L. Almassalha, S. Gladstein, Y. Li, T.Q. Nguyen, J. Chandler, G. Spicer, C. Sun, H.F. Zhang, V. Backman, “Multimodal Nanoscale Imaging of Chromatin with Super Resolution Microscopy and Partial Wave Spectroscopy”, SPIE Photonics West, San Francisco, CA, January 30, 2018.

18. V. Backman, “Convergence of Nanoimaging, Physics and Biology: Can Engineering Lead to a Cancer Cure?”, CLEO Conference, San Jose, CA, May 16, 2017.

19. V. Backman, “Low Angle Enhanced Backscattering Spectroscopy”, Digestive Disease Week, Chicago, IL, May 9, 2017.

20. G. Bauer, L. Almassalha, L. Cherkezyan, A. Kendra, S. Gladstein, J. Chandler, B. Seagle, H. Roy, I Szleifer, S. Shahabi, V. Backman, “Chromatin Protective Therapies: Live Cell Partial Wave Spectroscopic Microscopy as a Tool to Identify Adjuvant Compounds for Increased Chemotherapeutic Efficacy”, OSA Biophotonics Congress, San Diego, CA, April 2-5, 2017.

21. A. Stawarz, L. Almassalha, G. Bauer, J. Chandler, T. O’Halloran, V. Backman, “Live-cell Partial Wave Spectroscopy: Therapeutic and Biochemical Applications for Chromatin Research”, OSA Biophotonics Congress, San Diego, CA, April 2-5, 2017.

22. S. Gladstein, L. Almassalha, L. Cherkezyan, J. Chandler, H. Subramanian, I. Szleifer, V. Backman, “Integrated Imaging of the Cellular Nanoarchitecture and Molecular Motion”, OSA Biophotonics Congress, San Diego, CA, April 2-5, 2017.

23. L. Almassalha, A. Tiwari, L. Cherkezyan, H. Subramanian, I. Szleifer, H. Roy, V. Backman, “Imaging the Chromatin Nanoarchitecture Modulation of Gene Transcription”, OSA Biophotonics Congress, San Diego, CA, April 2-5, 2017.

24. V. Backman, “Convergence of Nano-Imaging, Physics and Biology: From Understanding Cancer Biology to Early Detection and Therapeutics”, SPIE Photonics West, San Francisco, CA, January 28- February 2, 2017.

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25. S. Gladstein, L. Almassalha, L. Cherkezyan, J.E. Chandler, A. Stephens, D. Zhang, W. Wu, H. Subramanian, J. Marko, I. Szleifer, V. Backman, “Label-free Imaging of Chromatin Nanoscale Dynamics: Integrated Imaging of the Cellular Nanoarchitecture and Molecular Motion”, SPIE Photonics West, San Francisco, CA, January 28- February 2, 2017.

26. B. Dong, L. Almassalha, Y. Stypula-Cyrus, B.E. Urban, J.E. Chandler, T.Q. Nguyen, C. Sun, H.F. Zhang, V. Backman, “Nanoscopic Imaging of Chromatin Topology Utilizing Intrinsic Fluorescence from Unmodified Nucleic Acids”, SPIE Photonics West, San Francisco, CA, January 28- February 2, 2017.

27. Y. Li, L. Cherkezyan, D. Zhang, L. Almassalha, E. Roth, J. Chandler, R. Bleher, H. Subramanian, V.P. Dravid, V. Backman, “Nanoscale Chromatin Structure Characterization for Optical Applications: A Transmission Electron Microscopy Study”, SPIE Photonics West, San Francisco, CA, January 28- February 2, 2017.

28. L. Almassalha, B. Dong, Y. Stypula-Cyrus, B.E. Urban, J.E. Chandler, T.Q. Nguyen, C. Sun, I. Szleifer, H.F. Zhang, V. Backman, “The Nanoscopic Topology of Chromatin: Implications of Physical Structure and Molecular Function”, SPIE Photonics West, San Francisco, CA, January 28- February 2, 2017.

29. D. Zhang, L. Cherkezyan, Y. Li, I. Capoglu, H. Subramanian, A. Taflove, V. Backman, “Histological Staining Can Enhance the Performance of Spectroscopic Microscopy on Sensing Nanoarchitectural Alterations of Biological Cells”, SPIE Photonics West, San Francisco, CA, January 28- February 2, 2017.

30. R. Liu, G. Spicer, S. Chen, H.F. Zhang, J. Yi, V. Backman, “A Theoretical Model for Optical Oximetry at the Capillary Level by Optical Coherence Tomography”, SPIE Photonics West, San Francisco, CA, January 28- February 2, 2017.

31. B. Dong, L. Almassalha, B.E. Urban, T.Q. Nguyen, S. Khuon, T.L. Chew, V. Backman, C. Sun, H.F. Zhang, “Spectroscopic Photon Localization Microscopy: Breaking the Resolution Limit of Single Molecule Localization Microscopy”, SPIE Photonics West, San Francisco, CA, January 28- February 2, 2017.

32. B.E. Urban, B. Dong, T.Q. Nguyen, V. Backman, C. Sun, H.F. Zhang, “Super-Resolution Localization Microscopy of Unstained Nanostructures”, SPIE Photonics West, San Francisco, CA, January 28- February 2, 2017.

33. A. Eid, D. Zhang, J. Yi, V. Backman, “FDTD Based Model of ISOCT Imaging for Validation of Nanoscale Sensitivity”, SPIE Photonics West, San Francisco, CA, January 28- February 2, 2017.

34. V. Backman, “Insights into Hallmarks of Early Carcinogenesis Using Nanoscale-Sensing Optical Microscopy”, BMES Annual Meeting, Minneapolis, MN, October 6, 2016.

35. G. Bauer, L. Almassalha, A. Kendra, S. Gladstein, H.K. Roy, V. Backman, “Chromatin Protection Therapy: Physio-Chemical Modulation of the Chromatin Nanostructure to

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Prevent Chemoresistance”, Digestive Disease Week 2016, San Diego, CA, May 21-24, 2016.

36. T. Gao, A. Eshein, A. Radosevich, T.Q. Nguyen, S. Bhattacharya, C.M. Bliss, C. Huang, H.K. Roy, V. Backman, “Polarization Gated Spectroscopic Screening of Colonic Neoplasia: Importance of Race-Specific Biomarkers”, Digestive Disease Week 2016, San Diego, CA, May 21-24, 2016.

37. L. Cherkezyan, D. Zhang, H. Subramanian, A. Taflove, V. Backman, “Spectroscopic Microscopy Explicitly Measure the Subdiffractional Structure of Biomaterials”, OSA Biomedical Optics Congress, Ft. Lauderdale, FL, April 25-28, 2016.

38. H. Subramanian, P. Viswanathan, R. Iyengar, L. Cherkezyan, M. Verleye, S. Rozhok, A. Gandhi, J. Derbas, J. Czarnecki, H.K. Roy, V. Backman, “Risk-Stratification of Lung Cancer Using Buccal Nanocytology”, OSA Biomedical Optics Congress, Ft. Lauderdale, FL, April 25-28, 2016.

39. H.K. Roy, H. Subramanian, A. Radosevich, S. Gladstein, V. Backman, A. Eshein, “Field Carcinogenesis Detection for Colon Cancer Screening: A Novel Application of Biophotonics”, OSA Biomedical Optics Congress, Ft. Lauderdale, FL, April 25-28, 2016.

40. J. Winkelmann, G. Spicer, A. Eid, J. Yi, V. Backman, “Visible Inverse Spectroscopic Optical Coherence Tomography Probe for Spatially Resolved Nanoscale Characterization” (Poster), OSA Biomedical Optics Congress, Ft. Lauderdale, FL, April 25-28, 2016.

41. A. Eshein, W. Wu, T.Q. Nguyen, A.J. Radosevich, V. Backman, “A Fiber Optic Probe to Measure Spatially Resolved Diffuse Reflectance in the Sub-Diffraction Regime for In-Vivo Use”, SPIE Photonics West, San Francisco, CA, February 13-17, 2016.

42. A. Eshein, T.Q. Nguyen, A.J. Radosevich, B. Gould, W. Wu, V. Konda, L.W. Yang, A. Koons, S. Feder, V. Valuckaite, H.K. Roy, V. Backman, “An Optical Spectroscopy Instrument Designed for In-Vivo Use in a Primary Care Clinical Setting”, SPIE Photonics West, San Francisco, CA, February 13-17, 2016.

43. J. Yi, W. Liu, S. Chen, V. Backman, N. Sheibani, C.M Sorenson, A.A. Fawzi, R.A. Linsenmeier, H.F. Zhang, “Visible Light Optical Coherence Tomography Measure Retinal Oxygen Metabolic Response to Systemic Oxygenation”, SPIE Photonics West, San Francisco, CA, February 13-17, 2016.

44. R. Liu, J. Yi, S. Chen, H.F. Zhang, V. Backman, “A Model for Oxygen-Dependent Backscattering Spectroscopic Contrast from Single Red Blood Cells”, SPIE Photonics West, San Francisco, CA, February 13-17, 2016.

45. G. Spicer, S.T. Young, J. Yi, L.D. Shea, V. Backman, “ISOCT Study of Effects of Enzymatic Crosslinking of Collagen in Field Carcinogenesis”, SPIE Photonics West, San Francisco, CA, February 13-17, 2016.

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46. W. Wu, A.J. Radosevich, A. Eshein, T.Q. Nguyen, V. Backman, “Electric Field Monte Carlo Simulation for Studying the Backscattering Coherence Phenomenon with Diverging Beam Illumination from Fiber”, SPIE Photonics West, San Francisco, CA, February 13-17, 2016.

47. D. Zhang, T. Graff, S. Crawford, H. Subramanian, S. Thompson, J.R. Derbas, R. Lyengar, H.K. Roy, C.B. Brendler, V. Backman, “Partial Wave Spectroscopic Microscopy Can Predict Prostate Cancer Progression and Mitigate Over-Treatment”, SPIE Photonics West, San Francisco, CA, February 13-17, 2016.

48. S. Rao, S. Azarin, G. Spicer, G. Bushnell, B. Aguado, J. Stoehr, V. Backman, J. Jeruss, L. Shea, “Implantable Micro-porous Poly(&[epsilon]-caprolactone) Scaffolds For Early Detection of Breast Cancer Metastasis”, BMES 2015 Annual Meeting, Tampa, FL, October 7-10, 2015 (Poster)

49. G. Bauer, L. Almassalha, J. Chandler, S. Gladstein, Y. Stypula-Cyrus, D. Zhang, L. Cherkezyan, H. Subramanian, I. Szleifer, V. Backman, “BaSIS: Imaging the Native, Living Cellular Nanoarchitecture”, BMES 2015 Annual Meeting, Tampa, FL, October 7-10, 2015 (Poster)

50. Q. Miao, J. Derbas, A. Eid, S. Young, H. Subramanian, V. Backman, “Automatic Cell Selection Method for Pap Smear Test”, BMES 2015 Annual Meeting, Tampa, FL, October 7-10, 2015 (Poster)

51. G. Spicer, J. Yi, S. Azarin, S. Young, J. Winkelmann, A. Eid, R. Liu, L. Shea, V. Backman, “Inverse Spectroscopic Optical Coherence Tomography Study of ECM Interactions in Cancer”, BMES 2015 Annual Meeting, Tampa, FL, October 7-10, 2015 (Poster)

52. A. Stawarz, R. Kalman, H. Subramanian, D. Zhang, H. Roy, V. Backman, “Detectable Nanoscale Alterations for Prediction of Future Risk of Hepatocellular Carcinoma”, BMES 2015 Annual Meeting, Tampa, FL, October 7-10, 2015 (Poster)

53. Y. Stypula, S. Gladstein, L. Almassalha, G. Bauer, J. Chandler, L. Cherkezyan, D. Zhang, H. Subramanian, I. Szleifer, V. Backman, “A Novel Spectroscopic Technology to Image the Native Chromatin Nanostructure in Live Cells”, AACR Chromatin and Epigenetics in Cancer, Atlanta, GA, September 25, 2015 (Poster)

54. V. Backman, “In Vitro Nanocytology Test for Highly Accurate Early Cancer Screening and Prognostication in Primary Care Setting”, Point-of-Care Diagnostics Conference, San Diego, CA, June 11, 2015 (Invited Talk)

55. V. Backman, “Elastic Light Scattering for Early Malignancy Detection in GI Tract”, Digestive Disease Week 2015, Washington, D.C., May 17-19, 2015 (Invited Talk)

56. T. Gao, M. DeLaCruz, A. Radosevich, B. Gould, V. Backman, H.K. Roy, “Differential Early Metabolic Changes in Colon Carcinogenesis for Health Disparities: Physiological and Molecular Evidence”, Digestive Disease Week 2015, Washington, D.C., May 17-19, 2015. (Poster)

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57. T. Gao, A. Radosevich, B. Gould, C. Bliss, C. Huang, D. Lichtenstein, T. Moore, D. Nunes, V. Backman, H.K. Roy, “Race and Gender Predilection for Spectroscopic Rectal Microvascular Markers in Colonic Field Carcinogenesis Detection: Implications for Colorectal Cancer Screening”, Digestive Disease Week 2015, Washington, D.C., May 17-19, 2015. (Poster)

58. R. Kalman, H. Subramanian, D. Nunes, M. DeLaCruz, R.K. Wali, L. Jepeal, A. Stawarz, D. Zhang, V. Backman, H.K. Roy, “Biophotonic Detection of High Order Chromatin Alterations in Field Carcinogenesis Predicts Risk of Future Hepatocellular Carcinoma: A Pilot Study”, Digestive Disease Week 2015, Washington, D.C., May 17-19, 2015.

59. S. Ruderman, V. Valuckaite, A. Almoghrabi, J. Hart, H.K. Roy, M. Bissonnette, V. Konda, V. Backman, “Early Angiogenic Changes Associated with Field Carcinogenesis in Experimental Colon Cancer”, Digestive Disease Week 2015, Washington, D.C., May 17-19, 2015.

60. V. Valuckaite, S. Ruderman, A. Almoghrabi, J. Hart, A. Abdyrakov, H.K. Roy, V. Backman, M. Bissonnette, V. Konda, “A Novel use of Angiotensin II Receptor Blocker (ARB) Losartan to Inhibit AOM Induced Tumorigenesis and Neoangiogenesis in Experimental Colon Cancer”, Digestive Disease Week 2015, Washington, D.C., May 17-19, 2015.

61. “Cancer Screening and Nanoscale Cytology”, SPIE Photonics West, San Francisco, CA, February 7, 2015 (Invited Talk).

62. W. Wu, A. Radosevich, Q. Nguyen, S. Young, Y. Li, A. Eshein, G. Spicer, H.K. Roy, V. Backman, “Calculating Optical Properties of Specific Structure Inside Tissue Using Transmission Electron Microscopy (TEM)”, SPIE Photonics West, San Francisco, CA, February 7-12, 2015.

63. A. Eshein, A. Radosevich, N. Mutyal, Q. Nguyen, W. Wu, B. Gould, H.K. Roy, V. Backman, “In-Vivo Assessment of Ultra-Structural Alterations as an Early Event in Cancer Progression: Implications for Cancer Screening”, SPIE Photonics West, San Francisco, CA, February 7-12, 2015.

64. D. Zhang, I. Capoglu, L. Cherkezyan, H. Subramanian, A. Taflove, V. Backman, “Spectroscopic Microscopy Characterization of Subdiffractional Surface Roughness with FDTD Validation”, SPIE Photonics West, San Francisco, CA, February 7-12, 2015.

65. S. Young, A. Radosevich, W. Wu, S. Vogt, L. Almassalha, Q. Jin, S. Chen, T. Paunesku, G. Woloschak, V. Backman, “Investigating Field Carcinogenesis Using X-Ray Fluorescence Microscopy” (Poster), SPIE Photonics West, San Francisco, CA, February 7-12, 2015.

66. S. Gladstein, S. Thompson, L. Almassalha, G. Bauer, J. Chandler, Y. Stypula-Cyrus, H. Subramanian, I. Szleifer, V. Backman, “Label-Free Live Cell Measurement of Nanoscale Cellular Architecture”, SPIE Photonics West, San Francisco, CA, February 7-12, 2015.

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67. “Transforming Risk Screening in Primary Care Setting”, Point of Care Diagnostics World Congress, San Diego, CA, September 19, 2014 (Invited talk).

68. V. Backman, “Polarization gated spectroscopy”, Gordon Conference - Lasers In Medicine & Biology Conference, Holderness, NH, July 14-18, 2014 (Invited talk).

69. “Photonics Meets Biology: From Nanoscale Imaging to Winning the War on Cancer”, Japan-America Frontiers of Engineering (JAFOE) Conference, Tokyo, Japan, June 9, 2014 (Invited talk).

70. N. Momi, H. Subramanian, L. Bowen, M. DeLaCruz, J. Weinstein, R.K. Wali, V. Backman, H.K. Roy, “Paracrine signaling between pancreatic cancer and small intestinal cells as the biological underpinnings of duodenal alterations in field carcinogenesis: implications for screening”, Conference on Digestive Disease Week 2014, Chicago, IL May 3-6, 2014.

71. H.K. Roy, N.N. Mutyal, M.J. Goldberg, A. Radosevich, L.K. Bianchi, S. Bajaj, B.R. Gould, B. Parker, V. Backman, “Spectroscopic in vivo quantification of tissue scattering coefficient (uS’) as a marker of mass-density fluctuations in colonic field carcinogenesis: implications for screening”, Conference on Digestive Disease Week 2014, Chicago, IL May 3-6, 2014.

72. H.K. Roy, D. Damania, D.K. Rex, C.M. Bliss, H. Subramanian, L.K. Bianchi, V. Gupta, M.J. Goldberg, D. Nunes, D. Lichtenstein, R. Lowe, V. Backman, “Nanocytological analysis of field carcinogenesis as a potential guide for post-polypectomy surveillance colonoscopy” (Poster Session), Conference on Digestive Disease Week 2014, Chicago, IL May 3-6, 2014.

73. H.K. Roy, V. Turzhitsky, R.K. Wali, A. Radosevich, B.D. Jovanovic, G. DellaZanna, D.T. Rubin, M.J. Goldberg, L.K. Bianchi, M. DeLaCruz, L.M. Rodriguez, R.T. Chatterton, S. Skripkauskas, E. Poast, E. Richmond, R. Bergan, V. Backman, “Correlation of spectral signatures with rectal prostaglandinE2 levels as biomarkers for aspirin chemoprevention of colon carcinogenesis: results from a placebo-controlled double blinded phase 2B trial”, Conference on Digestive Disease Week 2014, Chicago, IL May 3-6, 2014.

74. V. Backman, “Spectral markers in colonic neoplasia: biological insights”, 27th EDRN Steering Committee Meeting, Houston, Texas, March 4-6, 2014.

75. J. Yi, Y. Stypula, A.J. Radosevich, N.N. Mutyal, H.K. Roy, V. Backman, “Study of chromatin compaction by inverse spectroscopic optical coherence tomography as one mechanism in colorectal field carcinogenesis”, SPIE Photonics West, San Francisco, CA February 1-5, 2014.

76. A. Doronin, A.J. Radosevich, V. Backman, I.V. Meglinski, “Comparison of two Monte Carlo models of propagation of coherent polarized light in turbid scattering media”, SPIE Photonics West, San Francisco, CA February 1-5, 2014.

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77. J. Chandler, H. Subramanian, K. Vyas, L. Cherkezyan, V. Backman, “Nanoscale disorder of biological samples mapped by whole-slide spectral microscopy”, SPIE Photonics West, San Francisco, CA February 1-5, 2014.

78. L. Cherkezyan, I.R. Capoglu, H. Subramanian, J. Chandler, V. Backman, “Subdiffractional length-scale sensitivity of spectroscopic microscopy”, SPIE Photonics West, San Francisco, CA February 1-5, 2014.

79. D. Damania, H. Subramanian, V. Backman, E. Anderson, M. Wong, O. McCarty, K.G. Phillips, “Network signatures of nuclear and cytoplasmic density alterations in a model of pre- and post-metastatic colorectal cancer”, SPIE Photonics West, San Francisco, CA February 1-5, 2014.

80. J. Chandler, H. Subramanian, C. Maneval, C. White, V. Backman, “High-Throughput Partial Wave Spectroscopic Microscopy for Early Cancer Detection”, Biomedical Engineering Society 2013 Annual Meeting, Seattle, WA September 25-28, 2013.

81. M.K. Patel, A. Gomes, D.J. Hardee, S.M. Crespo, M.O. Othman, M. Raimondo, T. A. Woodward, H.K. Roy, V. Backman, M.B. Wallace, “Polarization Gating Spectroscopy to Detect Pancreas Cancer – Final Results of the Pilot Study” (Poster), Conference on Digestive Disease Week 2013, Orlando, FL May 17-21, 2013.

82. M. DeLa Cruz, C. Blaha, A. Radosevich, R.K. Wali, D. Kunte, Y.E. Stypula, V. Backman, H.K. Roy, “Sirt6 as a Regulator for the Metabolic Alterations in Early Colon Carcinogenesis: Further Support for an Early “Warburg-like” Effect” (Poster), Conference on Digestive Disease Week 2013, Orlando, FL May 17-21, 2013.

83. H.K. Roy, A. Radosevich, R.K. Wali, A. Umar, G. Della'Zanna, B. Janovic, M.J. Goldberg, L.K. Bianchi, D.T. Rubin, L.M. Rodriguez, Tat-Kin Tsang, V. Turzhitsky, J. Shklovskaya, S. Skripkauskas, I. Helenowski, R. Bergan, V. Backman, “Phase 2b Randomized Placebo-Controlled Spectral Markers as Biomarkers for Colonic Chemoprevention with Aspirin: Correlation with Rectal Apoptosis but not Proliferation” (Poster), Conference on Digestive Disease Week 2013, Orlando, FL May 17-21, 2013.

84. A.K. Tiwari, H. Subramanian, C.D. Maneval, R.K. Wali, V. Backman, H.K. Roy, “Functional Characterization of SWI/SNF Chromatin Remodelling Complex Genes through Optical Interrogation of Nuclear Chromatin Nanoarchitecture” (Poster), Conference on Digestive Disease Week 2013, Orlando, FL May 17-21, 2013.

85. V.J. Konda, M. Gonzalez-Haba Ruiz, S. Ruderman, V. Valuckaite, U. Dougherty, R. Mustafi, A. Kulkarni, T. Chua, I. Waxman, V. Backman, J. Hart, M. Bissonnette, “Differential effects of tumor-promoting and tumor-inhibiting dietary fats on angiogenesis in normal and tumor-bearing colon” (Poster), Conference on Digestive Disease Week 2013, Orlando, FL May 17-21, 2013.

86. A.K. Tiwari, R.K. Wali, V. Backman, H.K. Roy, “Progressive Loss of ARID1a (P270) Expression During Early Stages of Colorectal Carcinogenesis is a Significant Determinant

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of the Colonic Epithelium Phenotype” (Poster), Conference on Digestive Disease Week 2013, Orlando, FL May 17-21, 2013.

87. A.K. Tiwari, H. Subramanian, C.D. Maneval, R.K. Wali, V. Backman, H.K. Roy, “Partial Wave Spectroscopic Microscopy: A Novel Tool to Assess Perturbation in the Cellular Transcriptional Activity During Colon Carcinogenesis”, Conference on Digestive Disease Week 2013, Orlando, FL May 17-21, 2013.

88. H.K. Roy, N.N. Mutyal, M.J. Goldberg, J.D. Rogers, L.K. Bianchi, V.J. Konda, A. Radosevich, A. Gomes, V. Backman, “Microvascular Biomarkers in the Endoscopically Normal Rectal Mucosa for Colon Neoplasia Risk Stratification: Results of a Training/Validation Dataset”, Conference on Digestive Disease Week 2013, Orlando, FL May 17-21, 2013.

89. H.K. Roy, N.N. Mutyal, S. Bajaj, J.D. Rogers, V.J. Konda, M.J. Goldberg, A. Radosevich, A. Gomes, J. Van Dam, V. Backman “Duodenal Spectral Markers for Field Carcinogenesis Detection of Pancreatic Cancer: Implications for Interductal Papillary Mucinous Neoplasia (IPMNS) Diagnosis and Management”, Conference on Digestive Disease Week 2013, Orlando, FL May 17-21, 2013.

90. Y.E. Stypula, J. Yi, C. Blaha, M. DeLa Cruz, D. Kunte, H.K. Roy, V. Backman, “Histone Deacetylase (HDAC) Expression as a Biomarker for Colorectal Cancer (CRC) Field Carcinogenesis: Role in High Order Chromatin Modulation”, Conference on Digestive Disease Week 2013, Orlando, FL May 17-21, 2013.

91. V. Backman, “Nanoarchitectural markers of early carcinogenesis”, 8th EDRN Scientific Workshop, Washington, DC, March 13, 2013.

92. V. Backman, “Optical nanocytology: transforming cancer screening and understanding chromatin modifications in early carcinogenesis”, ASME 2nd Global Congress on NanoEngineering for Medicine and Biology, Boston, MA, February 6, 2013 (Keynote talk)

93. A. Gomes, V. Backman, “An algorithm for automated selection of application-specific fiber optic probes”, SPIE Photonics West, San Francisco, CA, February 2-7, 2013 (Talk)

94. J. Yi, H. Roy, V. Backman, “Quantifying the tissue structural changes under the field effect of colorectal cancer by inverse spectroscopic optical coherence tomography”, SPIE Photonics West, San Francisco, CA, February 2-7, 2013 (Talk)

95. J. Yi, V. Backman, “Imaging the complete set of optical and physical properties of biological tissue using inverse spectroscopic optical coherence tomography”, SPIE Photonics West, San Francisco, CA, February 2-7, 2013 (Talk)

96. L. Cherkezyan, I.R. Capoglu, H. Subramanian, D. Damania, V.Backman, “Spectroscopic microscopy for quantification of nanoscale refractive index fluctuations”, SPIE Photonics West, San Francisco, CA, February 2-7, 2013 (Talk)

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97. A.J. Radosevich, N.N. Mutyal, J.D. Rogers, V. Backman, “Three models of light transport at subdiffusion lengthscales measured with coherent backscattering spectroscopy”, SPIE Photonics West, San Francisco, CA, February 2-7, 2013 (Talk)

98. J. Yi, Q. Wei, H. Zhang, V. Backman, “Surpassing the diffraction limited resolution by laser scanning structured illumination microscopy”, Biomedical Engineering Society (BMES) 2012 Annual Meeting, Atlanta, GA October 24-27, 2012 (Talk)

99. J. Yi, V. Backman, “Inverse spectroscopic optical coherence tomography: quantifying tissue refractive index correlation function with nanoscale sensitivity”, Biomedical Engineering Society (BMES) 2012 Annual Meeting, Atlanta, GA October 24-27, 2012 (Talk)

100. S. Ruderman, M. Gonzalez_Haba, U. Dougherty, A. Kulkarni, A. Fichera, I. Waxman, T. Pappas, A. Gomes, M. Bissonnette, V. Konda, V. Backman, “Structural and Spatial Image Analysis of Tumor Vascularity in Models of Experimental Colon Cancer”, Biomedical Engineering Society (BMES) 2012 Annual Meeting, Atlanta, GA, October 24-27, 2012 (Poster)

101. D. Damania, R. Bleher, J. Wu, J. Rogers, H. Subramanian, H.K.Roy, V. Backman, V. Dravid, “Visualizing Native Cell Nano-architecture during Early Carcinogenesis using Scanning Transmission Electron Microscopy”, Microscopy & Microanalysis Conference, Phoenix, AZ, July 31-August 2, 2012 (Poster)

102. Y.E. Stypula, A. Radosevich, D. Kunte, N.N. Mutyal, M. Dela Cruz, T.P. Gibson, W. Qi, H.K. Roy, V. Backman, "Ultrastructural Alterations in Microscopically Normal Duodenal Mucosa as a Biomarker for Pancreatic Cancer Field Carcinogenesis", Conference on Digestive Disease Week 2012, San Diego, CA, May 19-22, 2012 (Poster).

103. Y.E. Stypula, D. Damania, D. Kunte, H. Subramanian, M. Dela Cruz, A.C. Patel, H.K. Roy, V. Backman, "Nanoarchitectural Changes of Chromatin by Histone Deacetylase (HDAC) Dysregulation occurs in Colorectal Field Carcinogenesis", Conference on Digestive Disease Week 2012, San Diego, CA, May 19-22, 2012 (Poster).

104. M.K. Patel, A.J. Gomes, S.M. Crespo, D.J. Hardee, M.O. Othman, A. Lankarani, S. Ruderman, H.K. Roy, V. Backman, M.B. Wallace, “Polarization Gating Spectroscopy of Apparently Normal Duodenal Mucosa to Detect Pancreatic Cancer”, Conference on Digestive Disease Week 2012, San Diego, CA, May 19–22, 2012.

105. S. Bajaj, J. Yi, A. Radosevich, M.J. Goldberg, J.D. Rogers, L.K. Bianchi, E.F. Yen, S. Upadhye , T.K. Tsang, B. Parker, H.K. Roy , V. Backman, “Development of Novel Optical Technologies For Early Colon Carcinogenesis Detection Via Nanoscale Mass Density Fluctuations: Potential Implications for Endoscopic Diagnostics”, Conference on Digestive Disease Week 2012, San Diego, CA, May 19–22, 2012 (Talk).

106. H.K. Roy , N.N. Mutyal, M.J. Goldberg, H. Du, A. Radosevich, L. K. Bianchi, J.D. Rogers, E.F. Yen, T.K. Tsang, N. Krosnjar, B. Jancan, S. Upadhye, B. Parker, V. Backman, “In Situ Rectal Spectral Markers for Colonic Neoplasia Risk Stratification-A

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Blinded Validation Study”, Conference on Digestive Disease Week 2012, San Diego, CA, May 19–22, 2012 (Talk).

107. H.K. Roy , D. Damania, D. Kunte, H. Subramanian, M. DeLaCruz, M.J. Goldberg, J.D. Rogers, R.K. Wali, V. Backman, “Development of a Novel Biophotonic Assay for Colonic Field Carcinogenesis Detection: Implications for Colorectal Cancer Risk Stratification”, Conference on Digestive Disease Week 2012, San Diego, CA, May 19–22, 2012 (Poster).

108. H.K. Roy , N.N. Mutyal, A.Radosevich, S. Bajaj, J. Van Dam, V.J. Konda, J.D. Rogers, S. Upadhye, M.J. Goldberg, V. Backman, “Development and Clinical Performance of a Novel Low Coherence Enhanced Backscattering Spectroscopy (LEBS) Fiberoptic Probe for Duodenal Sensing of Pancreatic Cancer Risk”, Conference on Digestive Disease Week 2012, San Diego, CA, May 19–22, 2012 (Talk)

109. A.J. Gomes, S. Ruderman, M. DelaCruz, Mart, R. Wali, H.K. Roy, V. Backman, “In Vivo Measurement of Carcinogenesis-Associated Shape Alterations of the Refractive Index Correlation Function”, Optical Society of America Biomedical Optics (BIOMED) conference, Miami, FL, April 29-May 2, 2012.

110. N.N. Mutyal, A.J. Radosevich, S. Bajaj, S. Upadhye, J.D. Rogers, H.K. Roy, V. Backman, “In-vivo risk stratification of pancreatic cancer by evaluating optical properties in duodenal mucosa” Optical Society of America Biomedical Optics (BIOMED) conference, Miami, FL, April 29-May 2, 2012.

111. L. Cherkezyan, H. Subramanian, S. Yang, D. Damania, V. Backman, “Targeted Alteration of Real and Imaginary Refractive Index of Biological Cells by Histological Staining”, Optical Society of America Biomedical Optics (BIOMED) conference, Miami, FL, April 29-May 2, 2012.

112. J. Yi, A. Radosevich, J.D. Rogers, V. Backman, “Inverse spectroscopic Optical Coherence Tomography (ISOCT): non-invasively quantifying the complete optical scattering properties from weak scattering tissue”, Optical Society of America Biomedical Optics (BIOMED) conference, Miami, FL, April 29-May 2, 2012.

113. A.J. Radosevich, N.N. Mutyal, J.D. Rogers, S. Upadhye, A. Bogojevic, H.K. Roy, V. Backman, “Measurement of the spatial backscattering impulse-response in colon field carcinogenesis using enhanced backscattering (EBS) spectroscopy”, Optical Society of America Biomedical Optics (BIOMED) conference, Miami, FL, April 29-May 2, 2012.

114. H. Roy & V. Backman, “Lung Cancer Risk Determination with Low Coherence Enhanced Backscattering Spectroscopy (LEBS) Analysis of Buccal Mucosa”, European Lung Cancer Conference, Geneva, Switzerland, April 19, 2012 (Talk).

115. Y.E. Stypula, D. Damania, H. Subramanian, L. Cherkezyan, H.K. Roy, J. Marko, V. Backman, "Nanoarchitectural Alterations of Chromatin by Histone Deacetylase (HDAC) Dysregulation Measured using Partial Wave Spectroscopic (PWS) Nanocytology",

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Physical Sciences - Oncology Center (PS-OCs) Network Investigators' Meeting, Tampa Bay, FL, April 16-18, 2012 (Poster).

116. L. Cherkezyan, V. Konda, H. Subramanian, K. Wroblewski, D. Damania, L. Karl, M. J. Goldberg, I. Waxman, H. K. Roy, V. Backman "Subdiffractional differences in macromolecular density distribution detected in the field of esophageal cancer" SPIE Photonics West, San Francisco, CA, January 24-26, 2012 (Talk).

117. W. Yip, A. Gomes, V. Backman, A. Sahakian, "Polarized Monte Carlo simulation of blood vessel structure in colon tissue", SPIE Photonics West, San Francisco, CA, January 24-26, 2012 (Poster).

118. J. Yi, J.D. Rogers, I.R. Capoglu, A. Radosevich, Y. Stypula, H.K. Roy, A. Taflove, and V. Backman, “Quantifying sub-diffractional tissue mass density correlation function by Spectroscopic Optical Coherence Tomography”, SPIE Photonics West, San Francisco, CA, January 24-26, 2012 (Talk).

119. A.J. Radosevich, N.N. Mutyal, J.D. Rogers, V. Turzhitsky, V. Backman, “Experimental measurement of the optical properties of biological tissue using polarized enhanced backscattering (EBS) spectroscopy”, SPIE Photonics West, San Francisco, CA, January 24-26, 2012 (Talk).

120. P. Pradhan, D. Park, H. Subramanian, D. Damania, L. Cherkezyan, V. Backman, “Delay time spectroscopy: a novel method for measuring nanoscale disorder in a biological cell and its application to early cancer detection”, SPIE Photonics West, San Francisco, CA, January 24-26, 2012 (Talk).

121. D. Damania, H. Subramanian, L. Cherkezyan, Y. Zhu, C. White, P. Pradhan, H. Roy, V. Backman, “Measuring nanoscale refractive-index alterations in the field of ovarian cancer using partial wave spectroscopic microscopy ”, SPIE Photonics West Conference, San Francisco, CA, January 21-26, 2012 (Talk).

122. A.J Radosevich, J.D. Rogers, A. Taflove, V. Backman, “Jones Matrix Monte Carlo Simulation of Coherent Backscattering in Biological Media”, National Radio Science Meeting (NRSM), Boulder, CO, January 4-7, 2012.

123. I.R. Capoglu, A. Taflove, and V. Backman, “Angora: An open-source finite-difference time-domain software package,” National Radio Science Meeting, Boulder, CO, January 4-7, 2012.

124. V. Backman, “Cell imaging at the nanoscale: Detecting nuclear chromatin alterations in field carcinogenesis”, AACR 2011 Frontiers in Cancer Prevention Research, Boston, MA, October 22, 2011 (Talk).

125. V. Backman, "Partial wave spectroscopic microscopy: detecting alterations in cell nanoarchitecture in early carcinogenesis", IEEE Photonics 2011, Arlington, VA, October 13, 2011 (Talk).

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126. D. Damania, H. Subramanian, Y. Zhu, L. Cherkezyan, Y. Stypula, M.De La Cruz, C. White, P. Pradhan, H. Roy, V. Backman, “Optical sensing of cell nano-architecture during early carcinogenesis: implications to colorectal cancer screening”, Biomedical Engineering Society Annual Meeting, Hartford, CT, October 12-15, 2011 (Talk).

127. T. Tan, A. Taflove, V. Backman, “A proposed perfectly matched stratified medium FDTD TFSF sourced by inhomogeneous plane waves”, International Conference on Electromagnetics in Advanced Applications, Torino, Italy, September 12-16, 2011 (Talk).

128. I.R. Capoglu, A. Taflove, V. Backman, “FDTD simulation of a partially-coherent Gaussian Schell-model beam”, IEEE International Symposium on Antennas and Propagation, Spokane, WA, July 3-8, 2011.

129. V. Backman, “Sensing Nanostructure of Biological Cells: A Journey from a Fundamental Technology to Cancer Screening”, 17th Annual CNSF Exhibition, Washington D.C., May 11, 2011 (Poster).

130. V. Konda, L. Cherkezyan, H. Subramanian, V. Becker, M. Goldberg, J. Chennat, K. Leah, I. Waxman, H. Roy, V. Backman, “In situ low coherence enhanced backscattering spectroscopy (LEBS) for risk-stratification of colon carcinogenesis: implications for screening and surveillance”, Conference on Digestive Disease Week 2011, Chicago, IL, May 7–10, 2011. (Talk).

131. Y. Stypula, S. Crawford, H. Subramanian, A. Tiwari, D. Kunte, M. Cornwell, H. Roy, V. Backman, "Understanding biological mechanisms of nuclear disorder strength in early carcinogenesis", Conference on Digestive Disease Week 2011, Chicago, IL, May 7-10, 2011. (Poster).

132. H.K. Roy, D. Damania, H. Subramanian, M.J. Goldberg, D. Weinberg, E.F. Yen, L.K. Bianchi, D. Shah, M.S. Borkar, T.K. Tsang, M. Utrecht, N. Krosnjar, B. Jancan, V. Backman, “Nanocytological Detection of Field Carcinogenesis With Partial Wave Spectroscopy: A Novel, Highly Accurate Modality for Prediction of Concurrent and Future Neoplastic Risk”, Conference on Digestive Disease Week 2011, Chicago, IL, May 7 – 10, 2011.

133. Y. Stypula, N. Mutyal, A. Radosevich, S. Joshi, A. Tiwari, D. Kunte, M. De La Cruz, H. Roy, V Backman, "End binding protein (EB1) up-regulation in field carcinogenesis: implications for alterations measured by low-coherence enhanced backscattering (LEBS)", Conference on Digestive Disease Week 2011, Chicago, IL, May 7-10, 2011. (Poster of Distinction).

134. V. Backman, “Alterations in nuclear nanoscale architecture: optical imaging and the role in early carcinogenesis”, PS-OC Network Investigators’ Meeting, April 10-12, 2011, La Jolla, CA (Talk).

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135. V. Backman, “Physical principles of genomic regulation through cellular nanoscale structure and implications for initiation of carcinogenesis:”, American Physical Society March Meeting, March 21, 2011, Dallas, TX (Invited Talk).

136. L. Cherkezyan, H. Subramanian, V. Konda, C. Chang, D. Damania, I. Waxman, V. Backman, “Evaluating changes in optical properties of biological cells due to histological staining”, SPIE Photonics West Conference, San Francisco, CA, January 22-27, 2011.

137. D. Damania, H. Roy, H. Subramanian, M. De La Cruz, Y. Zhu, V. Backman “Quantification of field carcinogenesis in isolated colonocytes via partial wave spectroscopic microscopy: novel means of colorectal cancer (CRC) screening”, SPIE Photonics West Conference, San Francisco, CA, January 22-27, 2011.

138. H. Subramanian, H. Roy, D. Damania, M. Shah, L. Cherkezyan, P. Pradhan, V. Backman, “Optical screening for lung cancer using epithelial cells obtained from buccal mucosa (cheek cells)”, SPIE Photonics West Conference, San Francisco, CA, January 22-27, 2011.

139. S. Ruderman, S. Mueller, J.D. Rogers, V. Backman, “Design and implementation of an optical contact sensor to automate in-vivo data acquisition upon mucosa contact with a fiber optic light scattering probe”, SPIE Photonics West Conference, San Francisco, CA, January 22-27, 2011.

140. N.N. Mutyal, A. Radosevich, A. Tiwari, Y. Stypula, V. Turzhitsky, J.D. Rogers, R. Wali, H. Roy, V. Backman, “Influence of cellular precancerous structural changes on macroscopic light scattering optical properties”, SPIE Photonics West Conference, San Francisco, CA, January 22-27, 2011.

141. A.J. Radosevich, V.M. Turzhitsky, N.N. Mutyal, J.D. Rogers, V. Backman, “Depth-resolved measurement of blood supply using low-coherence enhanced backscattering spectroscopy (LEBS)” SPIE Photonics West Conference, San Francisco, CA, January 22-27, 2011.

142. I.R. Capoglu, A. Taflove, V. Backman, “Numerical electromagnetic simulation of spectroscopic microscopy: Applications in early-stage cancer detection,” USNC-URSI National Radio Science Meeting, Boulder, CO, January 2011.

143. N.N. Mutyal, V. Turzhitsky, J. Rogers, A. Radosevich, H. Roy, M. Goldberg, M. Jameel, A. Bogojevich, V. Backman, “Fiber optic probe for measuring changes in rectal micro architecture and vasculature in field of carcinogenesis: Implications for colon cancer risk stratification”, Biomedical Engineering Society Annual Meeting, Austin, Texas, October 6-9 2010.

144. H.K. Roy, D. Damania, M. Goldberg, H. Subramanian, D. Kunte, M. De La Cruz, V. Backman “A novel fecal assay for colorectal cancer screening utilizing detection of nanoscale alterations in colonocytes via partial wave spectroscopy microscopy”, 12th World Congress on Gastrointestinal Cancer, Barcelona, Spain, 30 June-3 July, 2010 (Talk).

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145. D. Damania, Y. Stypula, C. Will, H. Subramanian, J. Licht, J. Marko, V. Backman “Quantification of cellular nanoarchitecture during early carcinogenesis using partial wave spectroscopic microscopy”, Cell-line Exercise meeting of NCI, Los Angeles, CA, June 19, 2010.

146. L.A. Marcelino, J. Henss, V. Turzhitsky, A. Fang, J. Fung, M. Siple, H. Wolfman, K.W. Marks, V. Stoyneva, M. Westneat, J. Rogers, V. Backman, “The role of coral skeleton in enhancing light absorption by symbiont algae – Implications for coral bleaching”, American Society for Microbiology (AMS) 110th General Meeting, San Diego, CA, May 23-27, 2010.

147. S.D. Strasser, A. Taflove, V. Backman, "dpNSOM: A Novel Nanoscale Refractive Index Measurement Technique", Northwestern University Undergraduate Research Symposium, Evanston, Illinois, May 24, 2010.

148. H.K. Roy, N. Mutyal, M.J. Goldberg, J.D. Rogers, A.K. Tiwari, A. Radosevich, R.K. Wali, L. K. Bianchi, E.F. Yen, M. Jameel, A. Bogojevic, V. Backman, “Microvascular and Micro-Architectural Spectral Markers Having Synergistic Diagnostic Capabilities for Colon Neoplasia Risk Stratification”, Digestive Disease Week (DDW), New Orleans, LO, May 1-5, 2010.

149. H.K. Roy, N. Mutyal, A. Radosevich, M.J., Goldberg, A.K. Tiwari, V. Turzhitsky, R.K. Wali, L.K. Bianchi, E.F. Yen, M. Jameel, A. Bogojevic, V. Backman, “In situ Rectal Low-Coherence Enhanced Backscattering Spectroscopy (LEBS) With a Fiber-Optic Probe Provides Accurate Risk Stratification for Colorectal Neoplasia”, Digestive Disease Week (DDW), New Orleans, LO, May 1-5, 2010.

150. V.J. Konda, I. Waxman, L. Cherkezyan, H. Subramanian, F. Caira, K. Wroblewski, M. Bissonnette, J.S. Chennat, H.K. Roy, V. Backman, “Spectral Marker Differences in the Field of Esophageal Cancer”, Digestive Disease Week (DDW), New Orleans, LO, May 1-5, 2010.

151. H.K. Roy, D. Damania, R.K. Wali, H. Subramanian, D. Kunte, M. De La Cruz, A.K. Tiwari, V. Backman, “Wave Spectroscopy Microscopic (PWS) Analysis of Fecal Colonocytes for Field Carcinogenesis Detection: A Novel Modality for Colorectal Cancer (CRC) Screening”, Partial Digestive Disease Week (DDW), New Orleans, LO, May 1-5, 2010.

152. Y. Stypula, D. Damania, H. Subramanian, S. Joshi, A.K. Tiwari, T.P. Ward, D. Kunte, S.R. Gandhi, M. De La Cruz, R.K. Wali, H.K. Roy, V. Backman, “Nanoscale Alterations in Early Colon Carcinogenesis are Determined by Cytoskeletal Dysregulation in Microscopically Normal Mucosa”, Digestive Disease Week (DDW), New Orleans, LO, May 1-5, 2010.

153. Y. Stypula, N. Mutyal, V. Turzhitsky, M.L.Cornwell, R.K. Wali, A.K. Tiwari, S. Crawford, V. Backman, H.K. Roy, “Biophotonic Detection of Colonic Field Carcinogenesis: Spectral Slope Represents Fundamental Alterations in Crypt Architecture”, Digestive Disease Week (DDW), New Orleans, LO, May 1-5, 2010.

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154. H. Subramanian, D. Damania, K. Solanki, Y. Stypula, L.Cherkezyan, A. Tiwari, P. Pradhan, D. Kunte, H.K. Roy, V. Backman, “Partial Wave Spectroscopy and Its Relation to Nanoscale Disorder in Nuclear Architecture”, Optical Society of America Biomedical Optics (BIOMED) conference, Miami, FL, April 11-14, 2010.

155. N.N. Mutyal, V. Turzhitsky1, J.D. Rogers, A. Radosevich, H. Roy, M.J. Goldberg, M. Jameel, A. Bogojevich, V. Backman, “Design and Implementation of Fiber Optic Probe for measuring Field Effect of Carcinogenesis with Low- Coherence Enhanced Backscattering Spectroscopy (LEBS)”, Optical Society of America Biomedical Optics (BIOMED) conference, Miami, FL, April 11-14, 2010.

156. A. Radosevich, V. Turzhitsky, N.N. Mutyal, J.D. Rogers, H.K. Roy, V. Backman, “Reconstructing the Low-coherence Enhanced Backscattering Spectroscopy (LEBS) Peak Using p(r)”, Optical Society of America Biomedical Optics (BIOMED) Conference, Miami, FL, April 11-14, 2010.

157. J.D. Rogers, I.R. Capoglu, V. Stoyneva, V.M. Turzhitsky, V. Backman; “Modeling Spectral Dependence of Reduced Scattering Coefficient for Continuous Random Media with the Born Approximation”, Optical Society of America Biomedical Optics (BIOMED) conference, Miami, FL, April 11-14, 2010.

158. V. Turzhitsky, A. Fang, J. Fung, J. Henss, M. Siple, V. Stoyneva, J. D. Rogers, H. Wolfman, A. Radosevich, V. Backman, L.A. Marcelino, “Optical Characterization of Coral Skeleton with Low-Coherence Enhanced Backscattering Spectroscopy”, Optical Society of America Biomedical Optics (BIOMED) Conference, Miami, FL, April 11-14, 2010.

159. S.D. Strasser, A. Taflove, V. Backman, "Nanoscale Refractive Index Measurement via Near-field Scanning Optical Microscopy", Chicago Area Undergraduate Research Symposium, Chicago, Illinois, April 10, 2010.

160. H.K. Roy, A. Gomes, M.J. Goldberg, S. Ruderman, L.K. Bianchi, J. Rogers, E. Yen, V. Backman, “Field Effect Identification Via Spectroscopic Rectal Microvasculature Enables Accurate Proximal Neoplasia Detection by Flexible Sigmoidoscopy”, Annual General Meeting of the British-Society-of-Gastroenterology, Liverpool, U.K., March 22-25, 2010.

161. P. Pradhan, D. Damania, H. Joshi, A. Taflove, H. Roy, V. Dravid, V. Backman, “Quantification of Nanoscale Density Fluctuations in Biological Cells/Tissues: Inverse Participation Ratio (IPR) Analysis of Transmission Electron Microscopy Images and Implications for Early-Stage Cancer Detection,” American Physical Society March Meeting, Portland, Oregon, March 15–19, 2010.

162. I.R. Capoglu, J.D. Rogers, A. Taflove, V. Backman, “A statistical model of light scattering in biological continuous random media based on the Born approximation”, SPIE Photonics West Conference, San Francisco, CA, January 22-28, 2010.

163. D. Damania, H. Subramanian, A.K. Tiwari, Y. Stypula, P. Pradhan, H.K. Roy, V. Backman, “Detecting the role of cytoskeleton in nanoscale alterations of biological cells

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using partial wave spectroscopic microscopy”, SPIE Photonics West Conference, San Francisco, CA, January 22-28, 2010.

164. A.J. Gomes, V. Turzhitzsky, S. Ruderman, J. Rogers, V. Backman, “Influence of polarization-gated probe geometry and scattering properties on penetration depth distributions in turbid media: a Monte Carlo and experimental analysis”, SPIE Photonics West Conference, San Francisco, CA, January 22-28, 2010.

165. P. Pradhan, D. Damania, H. Roy, V. Backman, “Quantification of optical disorder due to nanoscale density fluctuations in biological tissue: inverse participation ratio (IPR) analysis of transmission electron microscopy images for early-stage cancer detection”, SPIE Photonics West Conference, San Francisco, CA, January 22-28, 2010.

166. P. Pradhan, D. Damania, V. Turzhitzsky, H. Roy, V. Backman, "Quantification of the Disorder Strength of Nanoscale Refractive Index Fluctuations of Biological Tissue: Inverse Participation Ratio (IPR) Analysis", SPIE Photonics West Conference, San Francisco, CA, January 22-28, 2010.

167. J.D. Rogers, V. Stoyneva, N.N. Mutyal, V.M. Turzhitsky, V. Backman, “Lensless LEBS: a simplifi ed geometry for low-coherence enhanced backscattering (LEBS)”, SPIE Photonics West Conference, San Francisco, CA, January 22-28, 2010.

168. S. Ruderman, V. Stoyneva, J.D. Rogers, A.J. Gomes, V. Backman, “Development and validation of multilayered scattering and absorbing polyurethane phantoms”, SPIE Photonics West Conference, San Francisco, CA, January 22-28, 2010.

169. S. Ruderman, V. Stoyneva, A.J. Gomes, J.D. Rogers, V. Backman, “Assessment of pressure, angle and temporal effects on polarization-gated spectroscopic probe measurements”, SPIE Photonics West Conference, San Francisco, CA, January 22-28, 2010.

170. H. Subramanian, D. Damania, P. Pradhan, L. Cherkezyan, I. Capoglu, A. Taflove, V. Backman, "Origin of Partial Wave Spectroscopic Signals in a weak refractive index medium", SPIE Photonics West Conference, San Francisco, CA, January 22-28, 2010.

171. V. Turzhitsky, N.N. Mutyal, J.D. Rogers, V. Backman, “Characterization of tissue scattering with speckle measurements under partial spatial coherence illumination”, SPIE Photonics West Conference, San Francisco, CA, January 22-28, 2010.

172. V.M. Turzhitsky, A.J. Radosevich, J.D. Rogers, N.N. Mutyal, V. Backman, “Measuring the transport mean free path, anisotropy coefficient, and shape of the phase function with low-coherence enhanced backscattering spectroscopy” SPIE Photonics West Conference, San Francisco, CA, January 22-28, 2010.

173. A.J. Gomes, S. Ruderman, J.D. Rogers, V. Backman, “Early increase in blood supply associated with premalignant colonic lesions detected by fiber optic polarization-gated spectroscopy”, SPIE Photonics West Conference, San Francisco, CA, January 22-28, 2010.

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174. I.R. Capoglu, A. Taflove, V. Backman, “Microscope in a computer: numerical imaging using the finite-difference time-domain method”, USNC-URSI National Radio Science Meeting, Boulder, CO, January 6-9, 2010.

175. J.D. Rogers, V. Turzhitsky, H. Subramanian, I.R. Capoglu, V. Backman, “Enhanced Backscattering Simulation using Monte Carlo to Simulate Short-range Light Transport in Weakly Scattering Media.” USNC-URSI National Radio Science Meeting, Boulder, CO, January 6-9, 2010.

176. H.K. Roy, V. Backman, “Field Carcinogenesis”, Early Detection Research Network, 6th. EDRN Scientific Workshop (NCI), Bethesda, MD, September 1, 2009.

177. H.K. Roy, V. Backman, “Biophotonics Screening for Lung Cancer”, 49th. Japanese Respiratory Society Scientific Meeting, Tokyo, Japan, June 7, 2009.

178. H.K. Roy, V. Turzhitsky, Y.L. Kim, M. J. Goldberg, J.D. Rogers, A. Gomes, M. Jameel, N. Hasabou, T.K. Tsang, V. Backman, “Field Carcinogenesis Detection by Rectal Spectral Markers Accurately Identifies Patients Harboring Proximal Advanced Adenomas”, Digestive Disease Week 2009: Distinguished Abstract Plenary Session, Chicago, IL, June 2, 2009.

179. H.K. Roy, A. Gomes, S. Ruderman, M.J. Goldberg, L.K. Bianchi, E.F. Yen, J.D. Rogers, M. Jameel, A.N. Bogojevic, V. Stoyneva, J.-S. Chang, V. Backman, “Spectroscopic Assessment of Microvascular Blood Content to Improve Flexible Sigmoidoscopy: Gender-Related Implications”, Digestive Disease Week 2009, Chicago, IL, June 2, 2009.

180. I.R. Capoglu, V. Backman, “Validation of the Born Approximation in 2-D weakly-scattering biological random media using the FDTD Method”, 2009 IEEE Antennas and Propagation Society International Symposium, North Charleston, SC, June 1-5, 2009.

181. H.K. Roy, V. Backman, “Spectroscopy in Colorectal Cancer Screening”, Digestive Disease Week, Chicago, IL, June 1, 2009.

182. H. Subramanian, P. Pradhan, D. Damania, D. Balikov, S. Maheshwari, V. Backman, "Detecting nanoscale refractive index fluctuations using Partial wave spectroscopic microscopy", OSA Optics and Photonics Congress, Vancouver, BC, Canada, April 2009.

183. P. Pradhan, H. Subramanian, D. Damania, H. Roy, V. Backman, "Mesoscopic light reflection spectroscopy of weakly disordered dielectric media: Nanoscopic to mesoscopic light transport properties of a single biological cell and ultra-early detection of cancer", American Physical Society March Meeting, Pittsburgh, PA, March, 16-20, 2009.

184. J. J. Simpson, I. Capoglu, V. Backman, “Using FDTD to Improve Our Understanding of PWS for Advancing Ultra Early-Stage Cancer Detection Techniques”, International Symposium on Antenna Technology and Applied Electromagnetics and the Canadian Radio Sciences Meeting, Banff, Canada, February 15 – 18, 2009.

185. H. Subramanian, H.K. Roy, P. Pradhan, D. Damania, J. Mohammed, Z. Bogojevic, V. Backman, "Optical methodology for detecting sub-wavelength refractive index variations

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in cells present in the field of carcinogenesis ", BiOS 2009, SPIE Photonics West, San Jose, CA, January 24-29, 2009.

186. P. Pradhan, D.P. Damania, V.M. Turzhitzsky, V. Backman, H.K. Roy, “Quantification of optical disorder in nanoscale mass density fluctuations in biological tissue: inverse participation ratio (IPR) analysis of transmission electron microscopy (TEM) images,” SPIE Photonic West, San Jose, CA. January 24-29 (2009).

187. J.D. Rogers, H. Subramanian, V. Turzhitsky, V. Backman, "Relationship of low-coherence enhanced backscattering spectroscopy measurements to optical properties of scattering media", Invited talk, BiOS 2009, SPIE Photonics West, San Jose, January 24-29, 2009.

188. A.J. Gomes, H.K. Roy, V. Turzhitsky, Y. Kim, J.D. Rogers, S. Ruderman, V. Stoyneva, M.J. Goldberg, L.K.Bianchi, E. Yen, A. Kromine, M. Jameel, V. Backman, "Measuring Mucosal Microvascular Blood Supply in Vivo using Polarization-Gated Spectroscopy to predict Risk of Colonic Neoplasia", SPIE Photonics West, San Jose, CA, January 24-29, 2009.

189. V. Backman, “Detecting alterations in cell nanoarchitecture with optical imaging: Implications for cancer detection”, Invited talk, Annual Optical Society of America Meeting, Frontiers in Optics (FiO)/Laser Science XXIV (LS) Conference, Rochester, NY, October 23, 2008.

190. H. Subramanian, P. Pradhan, J. Mohammed, Z. Bogojevic, H.K. Roy, R.E. Brand, C.Sturgis, V. Backman, "Detection of nanoscale alterations of field carcinogenesis using Partial wave spectroscopic microscopy", Biomedical Engineering Society (BMES) 2008 Annual Meeting, St. Louis, MO, October 2-4, 2008.

191. V. Backman, “Cancer screening: a remote sensing approach”, Coulter Foundation Meeting, Fort Lauderdale, FL, August 6-8, 2008.

192. V. Backman, “Probing tissue architecture at submicron scale: seeing beyond histology”, Gordon Conference - Lasers In Medicine & Biology Conference, Holderness, NH, July 20-25, 2008.

193. V. Backman, M. Siple, E. Daly, A. Fang, M. Westneat, V. Turzhitsky, J. Rogers, L. Marcelino, “Novel optical technique for characterization of light absorption and distribution in reef-building corals”, 11th. International Coral Reef Conference, Fort Lauderdale, FL, July 7-15, 2008.

194. V. Backman, M. Siple, E. Daly, A. Fang, M. Westneat, V. Turzhitsky, J. Rogers, L. Marcelino, “Characterization of optical properties of reef-building coral skeletons”, 11th. International Coral Reef Conference, Fort Lauderdale, FL, July 7-15, 2008.

195. J.J. Simpson, X. Li, A. Heifetz, V. Backman, “FDTD computational synthesis and analysis of the partial wave spectroscopy image of the inhomogeneous dielectric sphere”, APS/USNC/URSI 2008, San Diego, CA, July 5-11, 2008.

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196. J.D. Rogers, H. Subramanian, V. Turzhitsky, P. Pradhan, Y.L. Kim, A. Taflove, V. Backman, “Enhanced Backscattering for tissue characterization and diagnosis”, Invited talk, APS/USNC/URSI 2008, San Diego, CA, July 5-11, 2008.

197. I.R. Capoglu, A. Taflove, V. Backman, “Theory and simulation of electromagnetic wave propagation in 1-D random media”, APS/USNC/URSI 2008, San Diego, CA, July 5-11, 2008.

198. T.A. Hensing, H. Subramanian, H.K. Roy, D. Breault Z. Bogojevic, D. Ray, N. Hasabou, V. Backman, “Identification of malignancy-associated change in buccal mucosa with Partial Wave Spectroscopy (PWS): A potential biomarker for lung cancer risk”, American Society of Clinical Oncology Annual Meeting, Chicago, IL, May 30-June 3, 2008.

199. A. Heifetz, H. Subramanian, P. Pradhan, Y. Liu, X. Li, J. Rogers, D. Kunte, H.K. Roy, A. Taflove, R. Brand, V. Backman, “Partial Wave Spectroscopy (PWS) screening for pancreatic cancer”, Canary Foundation Annual Meeting, Palo Alto, CA, May 20-22, 2008.

200. R. Brand, H. Subramanian, H.K. Roy, N. Hasabou, V. Backman , “Pilot study examining changes induced in duodenal epithelial cells by different pancreatic diseases as measured by a novel optical Imaging modality, single-cell partial wave Spectroscopy Microscopy”, Digestive Disease Week (DDW), San Diego, CA, May 17-22, Gastroenterology, 134(4), A93-A93 (2008).

201. H.K. Roy, V. Turzhitsky, A. Gomes, M.J. Goldberg, J.D. Rogers, Y.L. Kim, T.K. Tsang, D. Shah, M.S. Borkar, M. Jameel, N. Hasabou, R. Brand, Z. Bogojevic, V. Backman, “Prediction of colonic neoplasia through spectral marker analysis from the endoscopically normal rectum: An ex vivo and in vivo study”, Digestive Disease Week (DDW), San Diego, CA, May 17-22, Gastroenterology, 134(4), A109-A109 (2008).

202. H.K. Roy, H. Subramanian, P. Pradhan, H.T. Lynch, D. Weinberg, Z. Bogojevic, N. Hasabou, J. Koetsier, R.K. Wali, S.J. Lanspa, M.J. Goldberg, D. Kunte, V. Backman, “Identification of inherited predisposition to colonic neoplasia through partial wave spectroscopic analysis of the microscopically normal colonic epithelium”, Digestive Disease Week (DDW) Conference, San Diego, CA, May 17-22, 2008.

203. D. Breault, H. Subramanian, D. Ray, N. Deep, T. Hensing, P. Pradhan, Z. Bogojevic, N. Hasabou, H. Roy, V. Backman, “Bio-Optical assessment of buccal mucosa: A novel risk marker for lung cancer”, American Thoracic Society, Toronto, Canada, May 16-21, 2008.

204. V. Backman, “Cancer Screening via Biophotonics: A “Remote Sensing” Approach”, (Invited Talk), Food and Drugs Administration (FDA), Washington, D.C., April 29, 2008.

205. V. Turzhitsky, Y.L. Kim, H.K. Roy, J.D. Rogers, A. Gomes, R.E. Brand, J.L. Hoogheem, M.J. Jung, M. Jameel, N. Hasabou, Z. Bogojevic, V. Backman, “Low-Coherence Enhanced Backscattering as a colon cancer screening technology”, Invited talk, Midwest Biomedical Engineering Conference (MBEC), Chicago, IL, April 4, 2008.

206. A.J. Gomes, Y. Kim, V. Turzhitsky, J. Rogers, V. Backman, “In vivo assessment of microvascular blood content in the rectal mucosa using Polarization-Gated Spectroscopy:

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Applications for colon cancer screening”, The Optical Society of America (OSA) - Biomedical Optics Topical Meeting (BIOMED), St. Petersburg, FL, March 16-19, 2008.

207. P. Pradhan, V. Turzhitsky, A. Heifetz, D. Damania, H. Subramanian, H.K. Roy, V. Backman, “Measurement of optical disorder strength due to the nanoscale refractive index fluctuations of tissues/cells: Inverse Participation Ratio (IPR) analysis of Transmission Electron Microscopy (TEM) images”, The Optical Society of America (OSA) - Biomedical Optics Topical Meeting (BIOMED), St. Petersburg, FL, March 16-19, 2008.

208. J.D. Rogers, V.M. Turzhitsky, N.N. Mutyal, A. Gomes, A. Kromin, V. Backman, “An endoscope compatible Low-Coherence Enhanced Backscattering Spectroscopy probe for cancer screening”, The Optical Society of America (OSA) - Biomedical Optics Topical Meeting (BIOMED), St. Petersburg, FL, March 16-19, 2008.

209. H. Subramanian, P. Pradhan, D. Kunte, N. Deep, H.K. Roy, V. Backman, “Single-Cell Partial Wave Spectroscopic microscopy”, The Optical Society of America (OSA) - Biomedical Optics Topical Meeting (BIOMED), St. Petersburg, FL, March 16-19, 2008.

210. V. Turzhitsky, Y.L. Kim, P. Pradhan, H.K. Roy, R.E. Brand, J.L. Hoogheem, M.J. Jung, M. Jameel, N. Hasabou, V. Backman, “Quantifying the Field Effect of carcinogenesis with Low-Coherence Enhanced Backscattering Spectroscopy (LEBS)”. The Optical Society of America (OSA) - Biomedical Optics Topical Meeting (BIOMED), St. Petersburg, FL, March 16-19, 2008.

211. P. Pradhan, V. Turzhitsky, H. Subramanian, A. Heifetz, D. Damania, J. L. Hoogheem, M. J. Jung, H. K. Roy, V. Backman, “Inverse Participation Ratio (IPR) analysis of transmission electron microscopy (TEM) images: Quantification of optical disorder strength due to nanoscale refractive index fluctuations of tissues/cells”, American Physical Society March Meeting, New Orleans, LA, March 10-14, Bulletin of the American Physical Society, 53(2): V16.7, 2008.

212. V. Turzhitsky, H. Roy, Y.L. Kim, Y. Liu, R. Brand, J. Hoogheem, M. Jameel, N. Hasabou, Z. Bogojevic, V. Backman, “Rectal Coherent Backscattering Spectroscopy to screen for colon cancer”, Invited talk, American Institute for Medical and Biological Engineering (AIMBE) 17th. Annual Event, Washington D.C, February 20-22, 2008.

213. H. Subramanian, P. Pradhan, N. Deep, V. Parikh, D. Kunte, H. Roy, V. Backman, “Single-cell partial-wave spectroscopic microscopy: early detection of cancer”, Invited talk, SPIE - Photonics West, Symposium on Biomedical Optics, 2008, San Jose, CA, January 18-24, 2008.

214. A. Heifetz, K. Huang, A. Taflove, V. Backman, “Near-field subdiffractional confinement of light by a dielectric microsphere at Mie resonance”, SPIE - Photonics West, Symposium on Biomedical Optics, San Jose, CA, January 18-24, 2008.

215. H. Subramanian, “Partial wave spectroscopy”, SPIE Chicago, Midwest Conference, Evanston, IL, November 11, 2007.

216. H. Subramanian; P. Pradhan Y. Liu, V. Parikh, N. Deep, V. Backman, "Alteration of nano-architecture of cell in early stages of carcinogenesis demonstrated by single cell

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Partial Wave Spectroscopy: Ultra-early detection of cancer”, SPIE Chicago, Midwest Conference, Evanston, IL, November 11, 2007.

217. V. Turzhitsky, Y.L. Kim, Y. Liu, R.K. Wali, H.K. Roy, V. Backman, “Low-coherence Enhanced Backscattering (LEBS) Spectroscopy for Colon Cancer Detection”, SPIE Chicago, Midwest Conference, Evanston, IL, November 11, 2007.

218. H. Subramanian, R. Brand, P. Pradhan, N. Deep, V. Parikh, N. Hasabou, D. Polidoro, C. Sturgis, V. Backman, "Pilot study determining the feasibility of diagnosing pancreatic cancer using single cell partial wave spectroscopy of the duodenal mucosa", American Pancreatic Association 2007 Annual Meeting, Chicago, IL, November 1-3, 2007.

219. H. Subramanian, P. Pradhan, V. Backman, "Partial wave spectroscopy: Understanding cell nano-architecture and its alteration in carcinogenesis", Biomedical Engineering Society (BMES) 2007 Annual Meeting, Los Angeles, CA, September 26-29, 2007.

220. V. Turzhitsky, Y.L. Kim, Y. Liu, H. Roy, R. Brand, A. Gomes, V. Backman, “Low-Coherence Enhanced Backscattering Spectroscopy: Less Invasive Early Cancer Detection,” Biomedical Engineering Society (BMES) 2007 Annual Meeting, Los Angeles, CA, September 26-29, 2007.

221. H. Subramanian, P. Pradhan, V. Backman, "Understanding cell nano-architecture and its alteration in carcinogenesis via Partial-wave spectroscopy", Frontiers in Optics - 2007, San Jose, CA, September 16-20, 2007.

222. A. Heifetz, K. Huang, A.V. Sahakian, X. Li, A. Taflove, V. Backman, “Experimental confirmation of enhanced backscattering induced by a photonic jet,” Frontiers in Optics / OSA Annual Meeting, San Jose, CA, September 16-20, 2007.

223. V. Backman, "Analysis of nanoarchitecture of buccal epithelium for lung cancer screening", 15th. EDRN Steering Committee Meeting, Ann Arbor, Michigan, September 17-19, 2007.

224. V. Backman, “Low coherence Enhanced Backscattering”, EMBS Annual Meeting, Lyon, France, August 23-26, 2007.

225. V. Backman, H. Roy, Y. Liu, H. Subramanian, P. Pradhan, “Partial wave microscopy: seeing beyond histopathology”, Invited talk, Clinical Pathology Meeting, Rosemont, IL, June 9-10, 2007.

226. H.K., Roy, V. Turzhitsky V, Y.L. Kim, et al., “Rectal spectral markers: A novel, accurate modality to risk-stratify for colorectal cancer (CRC)”, Digestive Disease Week, Washington, DC, May 19-24, 2007, Gastroenterology, 132(4): A88-A88 Suppl. 2 (2007).

227. H.K., Roy, V. Turzhitsky, M.J. Goldberg, et al., “Improving colonciscopic polyp detection through microvascular blood content analysis with four dimensional elastic light scattering fingerprinting (4d-Elf)”, Digestive Disease Week, Washington, DC, May 19-24, 2007, Gastroenterology, 132(4): A95-A96 Suppl. 2 (2007).

228. R.E. Brand, H. Subranmanian, C. Sturgis, et al., “A novel highly accurate bio-optical approach for improving the cytologic diagnosis of pancreatic adenocarcinoma (PC)”,

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Digestive Disease Week, Washington, DC, May 19-24, 2007, Gastroenterology, 132(4): A119-A119 Suppl. 2 (2007).

229. H.K. Roy, Y. Liu, H. Subramanian, et al., “Detection of the colorectal cancer (CRC) field effect through partial wave spectroscopic microscopy (PWS)”, Digestive Disease Week, Washington, DC, May 19-24, 2007, Gastroenterology, 132(4): A169-A169 Suppl. 2 (2007).

230. V. Backman, “Preneoplasia: Predicting the Behavior of the Early Lesion”, Invited talk, The Educational Session, Annual Meeting of the American Association for Cancer Research, Los Angeles, CA, April 14, 2007.

231. H. Subramanian, P. Pradhan, Y.L. Kim et al., “Penetration depth of low-coherence enhanced backscattering photons in the sub-diffusion regime”, American Physical Society March Meeting, Denver, CO, March 5-9, Bulletin of the American Physical Society, 52(1):B30.7 (2007).

232. P. Pradhan, H. Subramanian, Y. Liu et al., “Application of mesoscopic light transport theory to ultra-early detection of cancer in a single biological cell,” American Physical Society March Meeting, Denver, CO, March 5-9, Bulletin of the American Physical Society, 52(1):B41.13 (2007).

233. Y.L.Kim, P. Pradhan, M.H. Kim, V. Backman, “Circular polarization memory effect in low-coherence enhanced backscattering of light”, American Physical Society March Meeting, Denver, CO, March 5-9, Bulletin of the American Physical Society, 52(1):B30.6 (2007).

234. A. Heifetz, K. Huang, A. Sahakian, X. Li, A. Taflove, V. Backman, “Experimental Confirmation of Backscattering Enhancement Induced by a Photonic Jet.”, American Physical Society March Meeting, Denver, CO, March 5-9, Bulletin of the American Physical Society, 52(1):B38.14 (2007).

235. A. Heifetz, K. Huang, A.V. Sahakian, X. Li, A. Taflove, V. Backman, “Experimental confirmation of enhanced backscattering induced by a photonic jet,” American Physical Society Annual March Meeting, Denver, CO, March 4-6, 2007.

236. H. Subramanian, P. Pradhan, Y.L. Kim et al., “Penetration depth of low-coherence enhanced backscattering photons in the subdiffusion regime”, SPIE Symposium on Biomedical Optics, San Jose, January 20-25, 2007.

237. Y.L. Kim, P. Pradhan, V. M. Turzhitsky, H. Subramanian, R.K. Wall, H.K. Roy, V. Backman, “Low-coherence Enhanced Backscattering: characteristics and applications for colon cancer screening”, Invited talk, SPIE - Photonics West, Symposium on Biomedical Optics, San Jose, CA, January 20-25, 2007.

238. P. Pradhan, H. Subramanian, Y. Liu et al., “Alteration of nanoscale cell architecture in early stages of carcinogenesis demonstrated by single cell partial wave spectroscopy: ultra-early detection of cancer”, SPIE - Photonics West, Symposium on Biomedical Optics, San Jose, CA, January 20-25, 2007.

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239. A. Heifetz, K. Huang, A.V. Sahakian, X. Li, A. Taflove, V. Backman, “Detection of subwavelength-size metal particles via super-enhanced backscattering perturbation facilitated by microwave photonic jet”, SPIE Photonics West, Symposium on Biomedical Optics, San Jose, CA, January 20-25, 2007.

240. R. Brand, Y. Liu, C. Sturgis, et al., ”Feasibility of using biophotonics to assist in cytologic diagnosis of pancreatic cancer”, Pancreas, 33(4): 449-449 (2006).

241. Y.L. Kim, V.M. Turzhitsky, M.P. Siegel, Y. Liu, R.K. Wali, H.K. Roy, V. Backman, "Increased blood supply in colon precancer assessed by polarization light scattering spectroscopy," BMES (Biomedical Engineering Society) 2006 Annual Meeting, Chicago IL, October 11-14, 2006.

242. V. Backman, Y. Liu, P. Pradhan, X. Li, Y. L. Kim, R. K. Wali, H.K. Roy, A. Taflove, “Single cell partial wave spectroscopy: understanding alterations of intracellular nanoarchitecture in cancer”, Invited Talk, Annual Meeting of the Optical Society of America: Frontiers in Optics, Rochester, NY, October 8-12, 2006.

243. H. Subramanian, P. Pradhan, Y.L. Kim, V. Backman, “Penetration depth of low-coherence enhanced backscattering (LEBS) in sub-diffusion regime,” BMES (Biomedical Engineering Society) 2006 Annual Meeting, Chicago, IL, October 11-14, 2006.

244. Y.L. Kim, V.M. Turzhitsky, A Kromine, R.K. Wali, H.K. Roy, M.J. Goldberg, P. Vakil, R. Brusen, V. Backman, "Detection of increased blood supply in superficial colonic mucosa in early colon carcinogenesis," Optical Imaging 2006, Fifth Inter-Institute Workshop on Optical Diagnostic Imaging from Bench to Bedside at the National Institutes of Health, September 25-27, 2006.

245. Y.L. Kim, V.M. Turzhitsky, A Kromine, R.K. Wali, H.K. Roy, M.J. Goldberg, P. Vakil, R. Brusen, V. Backman, "Detection of increased blood supply in superficial colonic mucosa in early colon carcinogenesis," Optical Imaging 2006, Fifth Inter-Institute Workshop on Optical Diagnostic Imaging from Bench to Bedside at the National Institutes of Health, September 25-27, 2006.

246. Y. Kim, V. Backman, “Low-coherence enhanced backscattering for biomedical applications”, Optical Society of America Summer Topical Meeting on Coherent Optical Technologies and Applications (COTA), Whistler, BC, Canada, June 28-30, 2006.

247. Y.L. Kim, P. Pradhan, H. Subramanian, Y. Liu, M.H. Kim, V. Backman, "Probing minimal scattering events in coherent backscattering of light using low-coherence induced dephasing," Photonic Metamaterials: From Random to Periodic, Grand Island, The Bahamas, June 5-8, 2006.

248. V. Backman, “Biophotonics for Cancer Screening: Can Star Trek-like Diagnostics Become a Reality?” Invited talk, Northwestern University Alumni Association, May 3, 2006.

249. R. Brand, Y. Liu, Y. Kim, A. Kromine, H. Roy, N. Hasabou, D. Shah, V. Backman, “Spectral markers of the duodenum can detect pancreatic cancer”, Gastroenterology,

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130(4): A36-A36 Suppl. 2 (2006), Digestive Diseases Week, Los Angeles, CA, May 20-25, 2006.

250. H. Roy, Y. Kim, Y. Liu, M. Goldberg, N. Hasabou, V. Turzhitsky, M. Jameel, E. Elton, V. Backman, “Risk stratification for colonic neoplasia through enhanced backscattering spectroscopy analysis of the endocopically-normal rectal mucosa”, Gastroenterology, 130(4): A48-A48 Suppl. 2 (2006), Digestive Diseases Week, Los Angeles, CA, May 20-25, 2006.

251. H. Roy, Y. Liu, Y. Kim, M. Goldberg, N. Hasabou, V. Turzhitsky, M. Jameel, E. Elton, V. Backman, “Spectroscopic microvascular assessment from the endoscopically normal mucosa for colon adenoma identification”, Gastroenterology, 130(4): A102-A103 Suppl. 2 (2006), Digestive Diseases Week, Los Angeles, CA, May 20-25, 2006.

252. Y. Liu, “Elastic Light Scattering Fingerprinting to Detect the “Field-effect” of Carcinogenesis”, Biomedical Engineering Department, Georgia Tech/Emory University, May, 2006.

253. Y. Liu, V. Backman, “Elastic Light Scattering Fingerprinting for Early Cancer Diagnosis”, Intel Corporation, May, 2006.

254. Y.L. Kim, Y. Liu, V.M. Turzhitsky, R.K. Wali, H.K. Roy, V. Backman, "Risk-stratification of colon cancer using low-coherence enhanced backscattering spectroscopy," Biomedical Optics Topical Meeting, Fort Lauderdale, FL, March 19-22, 2006.

255. Y.L. Kim, P. Pradhan, H. Subramanian, Y. Liu, M.H. Kim, V. Backman, "Minimal scattering events in enhanced backscattering (EBS) of light: Origin of low-coherence EBS in discrete tissue models," Biomedical Optics Topical Meeting, Fort Lauderdale, FL, March 19-22, 2006.

256. H. Subramanian, P. Pradhan, Y.L. Kim, V. Backman, “Monte Carlo model of low-coherence enhanced backscattering (LEBS) from anisotropic disordered media,” Biomedical Optics Topical Meeting, Fort Lauderdale, FL, March 19-22, 2006.

257. Y. Liu, P. Pradhan, X. Li, Y. Kim, R. Wali, H. Roy, V. Backman, “Partial-wave spectroscopy to detect the initial stage of colon carcinogenesis”, Biomedical Optics conference, Optical Society of America Topical Meeting, Fort Lauderdale, FL, March 19-22, 2006.

258. Y. Liu, V. Backman, “Detecting the “Field-Effect” of Carcinogenesis Using Elastic Light Scattering Fingerprinting”, Beckman Laser Institute, University of California – Irvine, February, 2006.

259. Y. Liu, P. Pradhan, X. Li, Y. Kim, R. Wali, H. Roy, V. Backman, “Partial-wave spectroscopy for pre-neoplastic detection”, SPIE - Photonics West, Symposium on Biomedical Optics 2006, San Jose, CA, January 21-26, 2006.

260. H. Subramanian, P. Pradhan, Y.L. Kim, V. Backman, “Modeling Low-coherence Enhanced Backscattering(LEBS) using Photon random walk model of Light Scattering”,

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SPIE - Photonics West, Symposium on Biomedical Optics 2006, San Jose, CA, January 21-26, 2006.

261. Y.L. Kim, P. Pradhan, H. Subramanian, Y. Liu, M.H. Kim, V. Backman, "Origin of low-coherence enhanced backscattering of light in discrete tissue models: Double scattering," SPIE - Photonics West, Symposium on Biomedical Optics 2006, San Jose, CA, January 21-26, 2006.

262. Y. Liu, V. Backman, “Elastic Light Scattering Fingerpringting for Tissue Characterization”, Johnson & Johnson Consumer Companies, November, 2005.

263. Y. Liu, X. Li, Y. Kim, V. Backman, “Elastic backscattering spectroscopic microscopy”, Frontiers in Optics/Laser Science conferences, Tucson, AZ, October 2005.

264. Y.L. Kim, Y. Liu, V.M. Turzhitsky, R.K. Wali, H.K. Roy, V. Backman, "Low-coherence enhanced backscattering (LEBS) for colon cancer screening," Frontiers in Optics 2005, The 89th OSA Annual Meeting, Laser Science XXI, Tucson, AZ, October 16-20, 2005.

265. X. Li, A. Taflove, V. Backman, “Recent Developments in Optical Cellular-Level Diagnosis and Imaging Facilitated by Three-Dimensional FDTD Computational Electrodynamics Modeling”, National Radio Science Meeting, Boulder, CO, January 4-7, 2005.

266. G. Ameer, Y. Liu, V. Backman, “Spectroscopic Assessment of Cell-Material Interactions”, BMES 2005 Annual Meeting, Baltimore, MD, September 28-October 1, 2005.

267. V. Backman, “Enhanced backscattering of light reveals the initial events in colon carcinogenesis”, 27th Annual International Conference of the IEE Engineering in Medicine and Biology Society, Pre-conference workshop on Biomolecular Photonics and Imaging, Shanghai, China, September 1-4, 2005.

268. V. Backman, “Detecting Pre-Neoplastic Events in Colon Carcinogenesis by Means of Low-coherence Enhanced Backscattering Spectroscopy”, Engineering Conferences International, Advances in Optics for Biotechnology, Medicine and Surgery, Copper Mountain, Colorado, July 24-28, 2005.

269. Y. Liu, Y. Kim, P. Pradhan, X. Li, V. Backman, “Partial Wave Spectroscopic Microscopy”, Engineering Conferences International, Advances in Optics for Biotechnology, Medicine and Surgery, Copper Mountain, Colorado, July 24-28, 2005.

270. Y. Kim, Y. Liu, V. Turzhitski, H. Roy, R. Wali, M. Goldberg, V. Vackman, “Low-coherence Enhanced Backscattering Spectroscopy”, Engineering Conferences International, Advances in Optics for Biotechnology, Medicine and Surgery, Copper Mountain, Colorado, July 24-28, 2005.

271. X. Li, A. Taflove, V. Backman, “Light Backscattering is Sensitive to Nanoscale Tissue Architecture”, Engineering Conferences International, Advances in Optics for Biotechnology, Medicine and Surgery, Copper Mountain, Colorado, July 24-28, 2005.

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272. X. Li, A. Taflove, V. Backman, “Light-Scattering Spectra of Particles with Complex Geometries: Comparison of Forward Scattering and Backscattering”, IEEE AP-S International Symposium on Antennas and Propagation and USNC/URSI National Radio Science Meeting, Washington, DC, July 3-8, 2005.

273. X. Li, A. Taflove, V. Backman, “Modified FDTD near-to-Far Field Transformation for Calculating Backscattering of Strongly Forward-Scattering Objects”, IEEE AP-S International Symposium on Antennas and Propagation and USNC/URSI National Radio Science Meeting, Washington, DC, July 3-8, 2005.

274. X. Li, A. Taflove, V. Backman, “Photonic Nanojets and Their Interaction with Nanoparticles”, IEEE AP-S International Symposium on Antennas and Propagation and USNC/URSI National Radio Science Meeting, Washington, DC, July 3-8, 2005.

275. R.K. Wali, Y.L. Kim, H.K. Roy, J.L. Koetsier, Y. Liu, D.P. Kunte, J. Hart, M. Goldberg, V. Backman, "Nitric oxide regulates increased microvascular blood content in the premalignant colonic epithelium," Digestive Disease Week (The American Gastroenterological Association), Chicago, IL, May 14-19, 2005.

276. H. Roy, R, Wali, M, Goldberg, Y. Kim, Y. Liu, V. Backman, “A Novel Spectral Biomarker for Risk-stratification of Colonic Neoplasia”, Digestive Disease Week (The American Gastroenterological Association Annual Meeting), Chicago, Illinois, May 14-19, 2005.

277. H. Roy, R, Wali, M, Goldberg, Y. Kim, Y. Liu, V. Backman, “Coherence Backscattering Spectroscopy (CBS): A Novel Modality For Colorectal Cancer (CRC) Risk Stratification”, Digestive Disease Week (The American Gastroenterological Association Annual Meeting), Chicago, Illinois, May 14-19, 2005.

278. V. Backman, “Detecting Invisible Precursors of Cancer with Scattered Light”, Biomedical Engineering Seminar, University of Illinois, Urbana-Champaign, April 2005.

279. V. Backman, “Detecting Invisible Precursors of Cancer with Low-coherent Backscattering Spectroscopy”, Biomedical Engineering Seminar, Tufts University, March 2005.

280. V. Backman, “Coherent Backscattering Spectroscopy: A new Technique for Tissue Diagnosis”, Biomedical Engineering Seminar, Duke University, March 2005.

281. V. Backman, “Understanding Pre-Neoplastic Events in Colon Carcinogenesis Using Elastic Light Scattering”, Biomedical Engineering and Electrical Engineering Colloquium, Boston University, February 2005.

282. V. Backman, “Early Detection, Diagnosis, and Therapy of Cancer”, Keynote Presentation, BiOS Hot Topics Session, BiOS Symposium at Photonics West, January 22, 2005.

283. A. Kromine, V. Backman, “Endoscopically compatible fiber optic probe for early detection of colon cancer”, SPIE Symposium on Biomedical Optics, San Jose, January 2005.

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284. Y.L. Kim, Y. Liu, R.K. Wali, H.K. Roy, and V. Backman, “Low-coherent backscattering spectroscopy for tissue characterization”, SPIE Symposium on Biomedical Optics, San Jose, January 22-27, 2005.

285. Y. Liu, Y. Kim, V. Backman, “Development of a novel bioengineered tissue model and its application in the investigation of the depth selectivity of polarization-gating”, SPIE Symposium on Biomedical Optics, San Jose, January 22-27, 2005.

286. X. Li, Z. Chen, A. Taflove, V. Backman, “Numerical investigation of light-scattering spectra”, SPIE Symposium on Biomedical Optics, San Jose, January 22-27, 2005.

287. X. Li, Z. Chen, A. Taflove, V. Backman, “Analysis of Nanoparticles using Photonic Nanojet”, SPIE Symposium on Biomedical Optics, San Jose, January 22-27, 2005.

288. Y. Kim, Y. Liu, H. Roy, R. Wali, V. Backman, “Understanding Pre-Neoplastic Events in Colon Carcinogenesis Using Light Scattering”, Biomedical Engineering Seminar, University of Arizona, November 9, 2004.

289. V. Backman, “Detecting Invisible Precursors of Cancer with Scattered Light”, Invited presentation, Illinois Microscopy Society, Chicago, IL, November 19, 2004.

290. V. Backman, Y. Kim, Y. Liu, “Coherent Backscattering Spectroscopy: A new Technique for Tissue Diagnosis”, Invited presentation, BMES 2004 Annual Meeting, Philadelphia, PA, October 13-16, 2004.

291. Y. Kim, Y. Liu, H. Roy, R. Wali, V. Backman, “Detection of Preadenomatous Colon Carcinogenesis Using Low-Coherent Backscattering Spectroscopy”, BMES 2004 Annual Meeting, Philadelphia, PA, October 13-16, 2004.

292. Y. Liu, Y. Kim, V. Backman, “Investigation of depth selectivity of polarization-gating using a novel bioengineered tissue model”, BMES 2004 Annual Meeting, Philadelphia, PA, October 13-16, 2004.

293. X. Li, Z. Chen, A. Taflove, V. Backman, “Investigation of light-scattering spectra of micro-particles with biologically-relevant structures”, BMES 2004 Annual Meeting, Philadelphia, PA, October 13-16, 2004.

294. J. Allen, Y. Liu, V. Backman, G. Ameer, “Spectroscopic Translation of Cell Phenomics”, BMES 2004 Annual Meeting, Philadelphia, PA, October 13-16, 2004.

295. X. Li, Z. Chen, A. Taflove, V. Backman, “Equiphase-sphere approximation for characterizing light scattering by particles with complex geometries”, OSA Annual Meeting, FiO/LS, Rochester, NY, October 10-14, 2004.

296. Y. Kim, Y. Liu, H. Roy, R. Wali, V. Backman, “Detection of Pre-Dysplastic Stages of Colon Carcinogenesis Using Elastic Light Scattering Fingerprinting”, Fourth Inter-Institute Workshop on Optical Diagnostic Imaging from Bench to Bedside at the National Institutes of Health, September 20-22, 2004.

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297. Y. Kim, Y. Liu, V. Backman, “Coherent Backscattering Spectroscopy: A New Technique for Tissue Diagnosis”, IEEE/EMBS Conference, San Francisco, CA, September 1-4, 2004.

298. H.K. Roy, R.K. Wali, J. Koetsier, Y. Liu, Y. Kim, M.J. Goldberg, S.Y. Chang, J. Horwitz, V. Turzhitsky, V. Backman, “Increased mucosal blood supply is an early preneoplastic marker in colon neoplasia”, Gastroenterology, 126(4): A38-A38 Suppl. (2004).

299. R.K. Wali, H.K., Roy, J. Koetsier, Y. Kim, Y. Liu, M.J. Goldberg, V. Turzhitsky, V. Backman, “Preneoplastic alterations in micro-architecture of intestinal neoplasia in APC MIN mice as measured by four-dimensional elastic light scattering fingerprinting”, Gastroenterology, 126(4): A76-A77 Suppl. 2 (2004).

300. S.Y. Chang, H.K. Roy, Y. Kim, Y. Liu, M.J. Goldberg, R.K. Wali, V. Turzhitsky, J.P. Horwitz, V. Backman, “Four-dimensional elastic light-scattering fingerprinting (4D-ELF) provides accurate risk stratification for human colonic neoplasia”, Gastroenterology, 126(4): A342-A342 Suppl. 2 (2004).

301. S.H. Tsen, A. Taflove, J.T. Walsh, V. Backman, D. Maitland, “Pseudo-spectral time-domain Maxwell's equations solution of optical scattering by tissue-like structures”, Las. Surg. Med., 28, S16 (2004).

302. X. Li, Z. Chen, A. Taflove, V. Backman. “Analytical and Numerical Investigation of Forward and Inverse Problems of Light Scattering by Irregularly-Shaped Particles”, IEEE AP-S International Symposium on Antennas and Propagation and USNC/URSI National Radio Science Meeting to be held in Monterey, California, June 20-26, 2004.

303. H.K. Roy, R.K. Wali, J. Koetsier, Y. Liu, Y. Kim, M.J. Goldberg, S.Y. Chang, J. Horwitz, V. Turzhitsky, V. Backman. “Increased Mucosal Blood Supply is an Early Preneoplastic Marker in Colon Neoplasia”, Distinguished Abstract, Plenary Session, Digestive Disease Week (The American Gastroenterological Association), Orlando, May, 2004.

304. R.K. Wali, H.K. Roy, J. Koetsier, Y. Kim, Y. Liu, M. Goldberg, V. Turzhitsky, V. Backman. “Preneoplastic Alterations in Micro-Architecture of Intestinal Neoplasia in APC MIN mice as Measured by Four-Dimensional Elastic Light Scattering Fingerprinting”, Digestive Disease Week (The American Gastroenterological Association), Orlando, May, 2004.

305. S.Y. Chang, H.K. Roy, Y. Kim, Y. Liu, M.J. Goldberg, R.K. Wali, V. Turzhitsky, J.P. Horwitz, V. Backman. “Four-Dimensional Elastic Light-Scattering Fingerprinting (4D-ELF) Provides Accurate Risk Stratification for Human Colonic Neoplasia”, Digestive Disease Week (The American Gastroenterological Association), Orlando, May, 2004.

306. Y.L. Kim, Y. Liu, H. Roy, R. Wali, M. Goldberg, V. Backman, “Detection of Pre-Dysplastic Stages of Colon Carcinogenesis Using Elastic Light Scattering Fingerprinting”, NSF/NIH/NASA Image-Guided Interventions (IGI) for Medical Applications Workshop, Bethesda, MD, May 13-14, 2004.

307. Y. Kim, Y. Liu, V. Turzhitsky, V. Backman. “Coherent Backscattering Spectroscopy: A New Technique for Tissue Diagnosis”, Biomedical Optics conference, Optical Society of America Topical Meeting, Miami, FL, April 14-17, 2004.

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308. Y. Kim, Y. Liu, R. Wali, H. Roy, M. Goldberg, V. Turzhitsky, V. Backman. “Polarization Spectroscopy of Early Increase in Blood Supply in Predysplastic Stages of Colon Carcinogenesis”, Biomedical Optics conference, Optical Society of America Topical Meeting, Miami, FL, April 14-17, 2004.

309. Y. Liu, J. Yang, Y. L. Kim, V. Turzhitsky, G. Ameer, V. Backman. “Novel optical technique for characterization of materials”, Biomedical Optics conference, Optical Society of America Topical Meeting, Miami, FL, April 14-17, 2004.

310. Y. Liu, K. Chen, G. Ameer, V. Backman. "Engineering ultra-sharp light scattering resonances using structured nanospheres for multi-label molecular imaging", Biomedical Optics conference, Optical Society of America Topical Meeting, Miami, FL, April 14-17, 2004.

311. J. Allen, Y. Liu, Y. Kim, V. Backman, G. Ameer, “Novel Optical Technique for the Characterization of Materials”, Division of Biochemical Technology, the 227th ACS National Meeting, Anaheim, CA, March 28-April 1, 2004.

312. Y.L. Kim, Y. Liu, R. Wali, H. Roy, M. Goldberg, V. Backman, “Coherent Backscattering Spectroscopy: a new Technique for Probing Short Paths in Living Tissue and Early Precancer Detection”, Proceedings of SPIE vol. 5319, BiOS 2004, Photonics West, San Jose, CA, January 24-29, 2004

313. Y. Liu, K. Chen, G. Ameer, V. Backman, “Multilayer Resonant Light Scattering Nanoshells as a Novel Class of Nonbleaching Labels for Multimarker Molecular Imaging”, Proceedings of SPIE vol. 5326, BiOS 2004, San Jose, CA, January, 2004

314. Y. Liu, Y.L. Kim, V. Turzhinsky, J. Allen, G. Ameer, V. Backman, “Light Scattering Fingerprinting for Characterization of Smooth Muscle Cell Proliferation”, Proceedings of SPIE vol. 5319, BiOS 2004, Photonics West, San Jose, CA, January 24-29, 2004.

315. H.K. Roy, R.K. Wali, M.J. Goldberg, Y.L. Kim, Y. Liu, V. Backman, “Detection of Pre-Dysplastic Stages of Experimental Colon Carcinogenesis Using Light Scattering Fingerprinting”, Preventive GI Oncology Conference, Northbrook, IL, October, 2003.

316. Y.L. Kim, Y. Liu, R.K. Wali, H.K. Roy, M.J. Goldberg, A.K. Kromin, K. Chen, V. Backman, “Alterations of Tissue Nano/micro-architecture as Accurate Preneoplastic Marker in the Rat Model of Experimental Colon Carcinogenesis”, BMES Annual Fall Meeting, Nashville, TN, October 1-4, 2003.

317. Y. Liu, Y.L. Kim, R.K. Wali, H.K. Roy, M.J. Goldberg, A.K. Kromin, K. Chen, V. Backman, “Early Detection of Colon Carcinogenesis Process Using Polarization Light Scattering Spectroscopy”, BMES Annual Fall Meeting, Nashville, TN, October 1-4, 2003.

318. V. Backman, Z. Chen, A. Taflove, “New analytical and numerical methods to model light scattering by inhomogeneous non-spherical particles”, Optical Society of America Annual Meeting, Tucson, Arizona, October 5-9, 2003.

319. V. Backman, Y.L. Kim, Y. Liu, R.K. Wali, H.K. Roy, M.J. Goldberg, A.K. Kromine, K. Chen, “Diagnosis of the early pre-dysplastic stages of colon carcinogenesis using light

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scattering “fingerprints”, Optical Society of America Annual Meeting, Tucson, Arizona, October 5-9, 2003.

320. V. Backman, Y.L. Kim, Y. Liu, K. Chen, R. Wali, H. Roy, M. Goldberg, “Diagnosis of Pre-Dysplastic Stages of Colon Carcinogenesis Using Light Scattering “Fingerprints”, BMES Annual Fall Meeting, Nashville, TN, October 1-4, 2003.

321. Y.L. Kim, Y. Liu, R.K. Wali, H.K. Roy, M.J. Goldberg, A.K. Kromin, K. Chen, V. Backman, “Light Scattering Fingerprints of Initial Pre-dysplastic Events in Colon Carcinogenesis”, 25th Annual international conference of the IEEE engineering in medicine and biology society, Cancun, Mexico, September, 2003.

322. G. Ameer and V. Backman, “A scaffold for cardiovascular tissue engineering”, National Institutes of Health-RITE Grantee Meeting, Rockville, MD, September 23-24, 2003.

323. G. Popescu, C. Fang-Yen, L. Deflores, M. Chu, H. Iwai, M. Hunter, M. Kalashnikov, V. Backman, K. Badizadegan, C. Boone, G. Stoner, R. Dasari, M.S. Feld, “Seeing Small Biological Structures with Light”, Proceedings of 16 International Conference on Laser Spectroscopy, Australia, July 2003.

324. Y.L. Kim, Y. Liu, R. K. Wali, H.K. Roy, M.J. Goldberg, A.K. Kromin, K. Chen and V. Backman, “Comprehensive description of light scattering by simultaneous measurement of angular, spectral, and polarization dependence for characterization of tissue macroachitecture in normal and precancerous state”, SPIE– The International Society for Optical Engineering European Conference on Biomedical Optics, Munich, Germany, June, 2003.

325. Y. Kim, Y. Liu, R.K. Wali, H.K. Roy, M.J. Goldberg, A.K. Kromine, K. Chen, V. Backman. “Comprehensive Description of Light Scattering by Simultaneous Measurement of Angular, Spectral, and Polarization Dependence for Characterization of Tissue Macroachitecture in Normal and Precancerous State”, SPIE's European Conference on Biomedical Optics, June 2003.

326. Z. Chen, A. Taflove, V. Backman, “Light Scattering by Randomly Inhomogeneous Dielectric Spheres in the Resonant Range.” Proceedings of IEEE AP-S International Symposium and USNC/CNC/URSI National Radio Science Meeting, Columbus, Ohio, June 22-27, 2003.

327. Y. Liu, Y. Kim, R.K. Wali, H.K. Roy, M.J. Goldberg, A.K. Kromine, K. Chen, V. Backman. “Simultaneous Measurement of Angular and Spectral Properties of Light Scattering for Early Cancer Detection”, CLEO, Baltimore, May 2003.

328. H.K. Roy, R. Wali, Y.L. Kim, Y. Liu, M. Goldberg, A. Kromine, K. Chen, V. Backman, “Early Detection of Experimental Colon Carcinogenesis Utilizing Light Scattering Spectroscopy”, Digestive Disease Week (The American Gastroenterological Association), Orlando, May, 2003. Gastroenterology, 124(4), Supp.1, A-5 (2003).

329. R. Wali, H.K. Roy, Y.L. Kim, Y. Liu, M. Goldberg, A. Kromine, K. Chen, V. Backman, “Increased Mucosal Blood Flow is an Early Marker of Colon Carcinogenesis”,

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Gastroenterology, Digestive Disease Week (The American Gastroenterological Association), Orlando, May, 2003. Gastroenterology, 124(4), Supp.1, A-4 (2003).

330. Y. Kim, Y. Liu, R.K. Wali, H.K. Roy, M.J. Goldberg, A.K. Kromine, K. Chen, V. Backman. “Evidence of increased mucosal blood flow as an early marker for colon carcinogenesis detected using polarized light scattering spectroscopy”, 23rd Annual Meeting of American Society for Lasers in Medicine and Surgery. Anaheim, CA, April 2003.

331. Y. Liu, Y. Kim, R.K. Wali, H.K. Roy, M.J. Goldberg, A.K. Kromine, K. Chen, V. Backman. “Detection of the initial stages of colorectal carcinogenesis using polarized light scattering spectroscopy with multivariate statistical analysis”, 23rd Annual Meeting for American Society for Lasers in Medicine and Surgery. Anaheim, CA, April 2003.

332. K. Chen, Y. Kim, A.K. Kromin, Y. Liu, B. Wessels, M. Ulmer, V. Backman. “Detection of nanosphere sizes using UV light scattering spectroscopy beyond the diffraction limit”, 23rd Annual Meeting for ASLMS, Anaheim, CA, April 2003.

333. V. Backman, K. Chen, M.P. Ulmer, B.W. Wessels, M.S. Robinson, “An innovative light scattering technique for characterizing Martian soil.” 34th Lunar and Planetary Science Conference, Houston, TX, March 17-21, 2003.

334. V. Backman, “Spectroscopic Optical Imaging”, Proceedings of BMES Annual Meeting, Houston, TX, October, 2002.

335. V. Backman, M. Kalashnikov, V. Gopal, A. Wax, I. Georgakoudi, R. Gurjar, I. Itzkan, R.R. Dasari, L.T. Perelman, M.S. Feld, K. Badizadegan, “Alterations of sub-micron structure of epithelial cells undergoing neoplastic transformation”. Proceedings of Optical Society of America Topical Meeting, 2002.

336. R. Gurjar, V. Backman, I. Itzkan, R.R. Dasari, L.T. Perelman, M.S. Feld, K. Badizadegan, “Early Detection of Precancer Using Polarized Light Scattering Spectroscopy”, Proceedings of American Physical Society March Meeting 2000, Minneapolis, MN, 2000.

337. L.T. Perelman, V. Backman, I. Itzkan, R.R. Dasari, M.S. Feld, K. Badizadegan, “Polarized Light Scattering Spectroscopy of Epithelial Structures”, Conference on Lasers and Electro-Optics, OSA Technical Digest, Optical Society of America, Washington, DC, 530-531, 2000.

338. V. Backman, M.S. Feld, L.T. Perelman, “Detection of Early Cancer with Polarized Light Scattering Spectroscopic Imaging”, Harvard-MIT HST Forum, Boston, March, 2000.

339. R. S. Gurjar, L.T. Perelman, V. Backman, I. Itzkan, R.R. Dasari, M.S. Feld, “Polarized Light Scattering Spectroscopy for Diagnosis of Precancer”, Advances in Optics for Biology, Medicine and Surgery, New York, 1999.

340. V. Backman, L.T. Perelman, R. Gurjar, I. Georgiakoudi, K. Badizadegan, I. Itzkan, R.R. Dasari, M.S. Feld, “Polarized Light Scattering Spectroscopy for Quantitative Measurement of Epithelial Cell Morphology In Vivo”, OSA Annual Meeting, Santa Clara, California, September 26 - 30, 1999.

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341. V. Backman, R. Gurjar, , K. Badizadegan, G. Zonios, I. Itzkan, R. R. Dasari, J.M. Crawford, J. Van Dam, L.T. Perelman, M.S. Feld, “Light Scattering Spectroscopy for Early Cancer Diagnosis,” Proceedings of the ICOLS’99, 286-295, 1999.

342. L.T. Perelman, G. Zonios, V. Backman, R. Gurjar, I. Itzkan, R.R. Dasari, J. Van Dam, M.S. Feld, “Quantitative Analysis of Mucosal Tissues in Patients Using Light Scattering Spectroscopy,” Optical Tomography and Spectroscopy of Tissue III, RR Alfano, B Chance, BJ Tromberg, eds. SPIE Press, 3597, 474-479, 1999.

343. M. Fitzmaurice M. Wallace, L.T. Perelman, V. Backman, J.M. Crawford, M. Seiler, K. Badizadegan, S.J. Shields, I. Itzkan, R. Dasari, J. Van Dam, M.S. Feld, “Endoscopic Diagnosis of Dysplasia in Barrett's Esophagus”, Lab. Invest., 79: (1) 428 JAN (1999).

344. M. Fitzmaurice, M. Wallace, V. Backman, L.T. Perelman, J.M. Crawford, M. Seiler, K. Badizadegan, S.J. Shields, I. Itzkan, R. Dasari, J. Van Dam, M.S. Feld, “Endoscopic Diagnosis of Dysplasia in Barrett's Esophagus”, Modern Pathology, 12(1):75A (1999).

345. V. Backman, L.T. Perelman, M.S. Feld, “Polarized Light Scattering Spectroscopy for Quantitative Measurement of Epithelial Cellular Structures In Situ”, Harvard-MIT HST Forum, Boston, March, 1999.

346. M. Wallace, L.T. Perelman, V. Backman, J.M. Crawford, M. Fitzmaurice, M. Seiler, K. Badizadegan, S.J. Shields, I. Itzkan, R. Dasari, J. Van Dam, M.S. Feld, “Endoscopic Diagnosis of Dysplasia in Barrett’s Esophagus with Light Scattering Spectroscopy,” Meeting on Columnar Lined (Barrett’s) Esophagus, Boston, September 27-29, 1998.

347. L.T. Perelman, G. Zonios, V. Backman, M. Wallace, I. Itzkan, J. Van Dam, M.S. Feld, “Reflectance Spectroscopy for Analysis of Mucosal Tissue In Vivo: Method to Detect Early Precancerous Changes,” OSA Annual Meeting, Baltimore, MD, October 4-9, 1998.

348. L.T. Perelman, V. Backman, M. Wallace, G. Zonios, R. Manoharan, I. Itzkan, J. Van Dam, J.M. Crawford, M.S. Feld, “Measurement of Nuclear Size Distribution of Epithelial Tissues In Vivo for Diagnosis of Early Precancerous Changes Using Reflectance Spectroscopy,” Technical Digest. Summaries of Papers Presented at the Conference on Lasers and Electro-Optics. Conference, Washington, DC, 6, 87, 1998.

349. V. Backman, L.T. Perelman, G. Zonios, M. Wallace, I. Itzkan, J. Van Dam, M.S. Feld, “Epithelial Nuclear Light Scattering Signatures as Markers of Early Precancerous Changes,” OSA Annual Meeting, Baltimore, MD, October 4-9, 1998.

350. W.B. Wallace, S.J. Shields, L.T. Perelman, V. Backman, G. Zonios, R. Manoharan, K. Badizadegan, A. Nusrat, M. Seller, T. Hamano, I. Itzkan, C. Lima, M. Fitzmaurice, J.M. Crawford, J. Van Dam, M.S. Feld, “Fiber-optic Detection of Low-grade Dysplasia in Patients with Barrett's Esophagus Using Reflectance Spectroscopy”, Gastroenterology, 114(4) G1337 , Part 2, Suppl. S (1998).

351. V. Backman, L.T. Perelman, M.S. Feld, “In Vivo Diagnosis of Barrett’s Esophagus Dysplasia Using Reflectance Spectroscopy Quantitative Morphological Analysis”, Harvard-MIT Health Sciences and Technologies Forum, Boston, March, 1997.

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352. G. Zonios, J. VanDam, L.T. Perelman, V. Backman, R. Manoharan, M.S. Feld, “Quantitative Histological Analysis of Colonic Tissue Using Diffuse Reflectance Spectroscopy at Colonoscopy”, Gastrointest. Endosc., 45: (4) 80, Suppl. S (1997).

353. V. Backman, S.V. Bobashev, O.S. Vasyutinskii, “Influence of Stokes Parameters of Synchrotron Radiation on Photofragments’ Polarization”, Proceedings of XIVth International Conference on Atomic Physics, Boulder, Colorado, 1994.

PATENTS

1. V. Backman, J. Yi, H.F. Zhang, W. Liu, K. Patel, “Devices, methods and systems of functional optical coherence tomography”, U.S. patent No. 9,962,075, Issue date: May 8, 2018.

2. V. Backman, J.D. Rogers, B. Gould, N. Mutyal, A.J. Radosevich, “Prove Apparatus for Recognizing Abnormal Tissue”, U.S. patent No. 9,885,834, Issue date: February 6, 2018.

3. V. Backman, J. Yi, “Biological Tissue Analysis by Inverse Spectroscopic Optical Coherence Tomography”, U.S. patent No. 9,678,007, Issue date: June 13, 2017.

4. V. Backman, J. Yi, H.F. Zhang, W. Liu, “Devices, methods and systems of functional optical coherence tomography”, U.S. patent No. 9,619,903, Issue date: April 11, 2017.

5. V. Backman, J. Yi, H.F. Zhang, Q. Wei, “Methods and apparatus for laser scanning structured illumination microscopy and tomography”, U.S. patent No. 9,360,660, Issue date: June 7, 2016.

6. Y.L. Kim, V. Backman, H.K. Roy, M. Siegel, V. Turzhitsky, “Method of using the detection of early increase in microvascular blood content to distinguish between adenomatous and hyperplastic polyps”, U.S. patent No. 9,314,164, Issue date: April 19, 2016.

7. V. Backman, H. Subramanian, D. Damania, H. Roy, D. Kunte, M. De La Cruz, “Cancer screening by detection of ultrastructural and molecular markers”, U.S. patent No. 9,090,933, Issue date: July 28, 2015.

8. V. Backman, Y. Liu, Y. Kim, P. Pradhan, H. Subramanian, H. Roy, M. Goldberg, R. Brand, “Methods for Identifying Refractive-Index Fluctutations of a Target”, Japan patent No. 5744403, Issue date: May 15, 2015.

9. V. Backman, H. Roy, Y. Kim, Y. Liu, V. Turzhitsky, J.D. Rogers, “Systems, Method, and Apparatuses of Low-Coherence Enhanced Backscattering Spectroscopy”, Japan patent No. 5706948, Issue date: March 6, 2015.

10. V. Backman, H. Subramanian, D. Damania, H. Roy, D. Kunte, M. De La Cruz, “Cancer screening by detection of ultrastructural and molecular markers”, U.S. patent No. 8,735,075, Issue date: May 27, 2014.

11. V. Backman, H. Subramanian, J. Chandler, C. White, J. Rogers, L. Cherkezyan, “High throughput partial wave spectroscopic microscopy”, Serial No. 61/857,427, Application Date: July 23, 2013.

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12. V. Backman, H. Subramanian, J. Chandler, M. Proenca, “Automated cell collection and smearing”, Serial No. 61/786,802, Application Date: March 15, 2013.

13. V. Backman, H.Roy, R. Brand, Y. Liu, J. Rogers, V. Turzhitsky, “Systems, methods and apparatuses of elastic light scattering spectroscopy and low coherence enhanced backscattering spectroscopy”, U.S. patent No. 8,131,348 (Serial No. 11/803,418), US Class 600/476; 356/303, International Class A61B 6/00; G01J 3/40, Issue date: March 6, 2012.

14. V. Backman, Y. Liu, Y. Kim, H. Roy, M. Goldberg, R. Brand, P. Pradhan, S. Hariharan, “Method for identifying refractive-index fluctuations of a target”, US Patent No. 7,800,746, US Class 356/128, International Class G01N 21/41, Issue date: September 21, 2010.

15. V. Backman, Y. Liu, Y. Kim, “System for identifying refractive-index fluctuations of a target”, US Patent 7,667,832, US Class 356/128, International Class G01N 21/41, Issue date: February 23, 2010.

16. V. Backman, H. Roy, Y. L. Kim, Y. Liu, V. Turzhitsky, “Systems, methods, and apparatuses of low-coherence enhanced backscattering spectroscopy”, US Patent 7,652,772, US Class 356/497, International Class G01B 9/02, Issue date: January 26, 2010.

17. V. Backman, B. Gould, A. Cittadine, J. Rogers, H. Roy, “Probe apparatus for recognizing abnormal tissue”, U.S. patent application No. 20100262020, (Serial No. 61/143,407), Submission date: January 8, 2010.

18. V. Backman, H.Roy, A.Gomes, S. Ruderman, J. Rogers, “Method of screening for cancer using parameters obtained by the detection of early increase in microvascular blood content”, U.S. patent application No. 20090203977 (Serial No. 12/350,955), US Class 600/325, International Class A61B 5/1459, Submission date: August 13, 2009.

19. V. Backman, H. Roy, R. Wali, Y. L. Kim, M. Siegel, V. Turzhitsky, “Method of recognizing abnormal tissue using the detection of early increase in microvascular blood content”, U.S. patent application No. 20070179368 (Serial No. 11/604,653), US Class 600/315, International Class A61B 005/00, Submission date: August 2, 2007.

20. V. Backman, H. Roy, Y. L. Kim, Y. Liu, “Apparatus for recognizing abnormal tissue using the detection of early increase in microvascular blood content”, U.S. patent application No. 20070129615 (Serial No. 11/604,659), US Class 600/315, International Class A61B 005/00, Submission date: June 7, 2007.

21. V. Backman, H. Roy, R. Wali, Y. L. Kim, Y. Liu, G. Ameer, J. Yang, A. Webb, J. Allen, “Multi-dimensional elastic light scattering”, US Patent application No. 20060155178 (Serial No. 261,452), US Class 600/315, International Class A61B 005/00, Submission date: July 13, 2006.

22. L.T. Perelman, V. Backman, M.S. Feld, G. Zonios, I. Itzkan, R. Manoharan, “Method for Measuring Tissue Morphology”, US Patent 6,922,583, US Class 600/476, International Class 600/476, Issue date: July 26, 2005.

23. I. Georgakoudi, V. Backman, M.S. Feld, “Fluorescence, reflectance and light scattering spectroscopy for measuring tissue”, US Patent 6,697,652, US Class 600/310, International Class G01N 21/64, Issue date: February 24, 2004.

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24. V. Backman, R.R. Dasari, R. Gurjar, I. Itzkan, L. Perelman, M.S. Feld, “Polarized light scattering spectroscopy of tissue”, US Patent 6,624,890, US Class 356/369, International Class A61B 5/00, Issue date: September 23, 2003.

25. V. Backman, R.R. Dasari, R. Gurjar, I. Itzkan, L.T. Perelman, M.S. Feld, “Polarized Light Scattering Spectroscopy of Tissue”. US Patent 6,404,497, US Class 356/369, International Class G01J 004/00, Issue date: June 11, 2002.

26. I. Georgakoudi, V. Backman, M. Mueller, M.S. Feld, “Analysis of Chemical Composition and Structure of Tissues with Tri-Modal Spectroscopy”, US Patent Application, 2001.

27. L.T. Perelman, V. Backman, M.S. Feld, G. Zonios, I. Itzkan, R. Manoharan, “Measuring Tissue Morphology”, US Patent 6,091,984, US Class 600/476, International Class A61B 5/00, Issue date: July 18, 2000.

INVITED TALKS (For list of all talks, see Conference Presentations)

1. “Bridging Chromatin Nanoimaging and Molecular Modeling – What Can We Learn About Chromatin Packing as a Regulator of Transcription?”, University of Nebraska Medical Center, Omaha, NE, October 8, 2018.

2. “Chromatin Regulation to Fight Resistance in Cancer Chemotherapy”, Illinois Ignite Conference, Rosemont, IL, September 27, 2018.

3. “Bridging Chromatin Nanoimaging and Molecular Modeling – What Can We Learn About Chromatin Packing as a Regulator of Transcription?”, Telluride Workshop on Chromatin Structure and Dynamics, Telluride, CO, July 31, 2018.

4. “Convergence of Nanoimaging and Biology: From Decoding Chromatin Packing to Cancer Diagnostics and Therapeutics”, Center for Structural Systems Biology, Hamburg, Germany, April 10, 2018.

5. “Nanotechnology in Gastroenterology: Small Steps for Large Gains”, AGA Tech Summit, Boston, MA, March 22, 2018

6. “Convergence of Nanoimaging and Biology: From Decoding Chromatin Packing to Cancer Diagnostics and Therapeutics”, University of Notre Dame, South Bend, IN, February 2, 2018.

7. Congressional Briefing Panel by United for Medical Research, Rayburn House Office Building, Washington D.C., November 15, 2017.

8. “Convergence of Nanoimaging and Biology: From Decoding Chromatin Packing to Cancer Diagnostics and Therapeutics”, Robert H. Lurie Comprehensive Cancer Center, Chicago, IL, October 12, 2017.

9. “Convergence of Nanoimaging, Physics and Biology: Can Engineering Lead to a Cancer Cure?”, University of Chicago Department of Pathology, Chicago, IL, September 14, 2017.

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10. “Convergence of Nanoimaging, Physics and Biology: Can Engineering Lead to a Cancer Cure?”, CLEO Conference, San Jose, CA, May 16, 2017.

11. “Convergence of Nanoimaging, Physics and Biology: Can Engineering Lead to a Cancer Cure?”, Imperial College London, March 22, 2017.

12. “Label-Free Nanoscale Imaging: Uncovering a New Biological Code”, Massachusetts Institute of Technology, Cambridge, MA, November 22, 2016.

13. “Label-Free Nanoscale Imaging”, Columbia University, October 12, 2016

14. “Insights into hallmarks of early carcinogenesis using nanoscale-sensing optical microscopy”, BMES Annual Meeting, Minneapolis, MN, October 6, 2016.

15. “Convergence of Engineering, Physics and Biology: Insights into Hallmarks of Early Carcinogenesis, Early Cancer Detection and Therapeutics”, National Science Foundation Directorate of Engineering, Arlington, VA, July 19, 2016.

16. “Label-Free Nanoscale Imaging”, Massachusetts Institute of Technology, May 31, 2016.

17. “Nanocytology: Personalizing Cancer Risk Assessment in Primary Care Setting”, Midwestern Medical Director’s Association Annual Meeting, Chicago, IL, May 13, 2016.

18. “How To Win The War On Cancer”, Milken Global Conference, Los Angeles, CA, May 4, 2016.

19. “Insights into Hallmarks of Early Carcinogenesis Using Nanoscale-sensing Optical Microscopy”, Oregon Health Science University, Portland, OR, April 14, 2016.

20. “Insights into Hallmarks of Early Carcinogenesis Using Nanoscale-sensing Optical Microscopy”, University of Pennsylvania, Philadelphia, PA, April 7, 2016.

21. “Understanding Initial Stages of Carcinogenesis Using Label-Free Optical Nanoimaging and Nanosensing”, University of Wisconsin – Madison, Madison, WI, February 29, 2016.

22. “Understanding Hallmarks of Early Carcinogenesis Using Optical Nanoimaging and Nanosensing”, Northwestern University Feinberg School of Medicine, Department of Neurology, Chicago, IL, January 11, 2016.

23. “Optical Imaging Techniques in Early Cancer Detection”, 12th Annual Life Settlement and Longevity Conference, Washington DC, November 2, 2015.

24. “Improving Cancer Detection Methods”, Medical Breakthroughs at Chicago Ideas Week, Chicago, IL, October 17, 2015.

25. “Nanocytology: New Approaches to Cancer Screening”, University of Illinois-Chicago Department of Pathology, Chicago, IL, October 12, 2015.

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26. “Partial Wave Spectroscopy Prostate Cancer Project: Update and Future Goals”, NorthShore University HealthSystem, Evanston, IL, October 9, 2015.

27. “In Vitro Nanocytology Test for Highly Accurate Early Cancer Screening and Prognostication in Primary Care Setting”, Point of Care Diagnostics Conference, San Diego, CA, June 12, 2015.

28. “Nanosensing and Functional Biophotonics to Study Initial Stages of Carcinogenesis”, LAAMP Seminar, Beckman Laser Institute, Irvine, CA, April 28, 2015.

29. “Nanoscale and Functional Optical Imaging for Colon Cancer Diagnostics and Risk-Stratification”, University of Southern California, Los Angeles, CA, April 27, 2015.

30. “Cancer Screening and Nanoscale Cytology”, SPIE Photonics West Hot Topics, San Francisco, CA, February 6, 2015.

31. “Nanoncytology: Transforming Cancer Screening and Risk-Stratification”, NorthShore University HealthSystem Urological Research Group, Evanston, IL, December 5, 2014.

32. “Transforming Risk Screening in Primary Care Setting”, Point of Care Diagnostics World Congress, San Diego, CA, September 19, 2014.

33. V. Backman, “Polarization Gated Spectroscopy”, Gordon Conference - Lasers In Medicine & Biology, Holderness, NH, July 14-18, 2014.

34. “Partial Wave Spectroscopy”, Olympus Corporation, Tokyo, Japan, June 10, 2014.

35. “Photonics Meets Biology: From Nanoscale Imaging to Winning the War on Cancer”, Japan-America Frontiers of Engineering (JAFOE) Conference, Tokyo, Japan, June 9, 2014.

36. “Elastic Light Scattering for Early Malignancy Detection in GI Tract”, Digestive Disease Week 2015, Washington, D.C., May 19, 2015.

37. “Optical Imaging Detects Nanoscale Alterations in Early Carcinogenesis: Cost-Effective Risk-Stratification, Screening and Prognosis of Cancer”, NCI-NIBIB Point of Care Technologies for Cancer Conference, Bethesda, MD, January 8, 2014.

38. “New Optical Imaging for the Detection of Nanoscale Biomarkers of Field Carcinogenesis: Risk-Stratification, Screening and Prognosis of Cancer”, 26th EDRN Steering Committee Meeting, Seattle, WA, September 10, 2013.

39. “Nanoarchitectural Markers of Early Carcinogenesis”, 8th EDRN Scientific Workshop, Bethesda, MD, March 13, 2013.

40. “Optical Nanocytology: Transforming Cancer Screening and Understanding Chromatin Modifications in Early Carcinogenesis”, ASME 2nd Global Congress on Nanoengineering for Medicine & Biology, Boston, MA, February 6, 2013.

41. “Nanocytology: Transforming Colon Cancer Screening”, Early Detection Seminar, Stanford University, Palo Alto, CA, October 25, 2012.

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42. “Nanocytology: Transforming Colon Cancer Screening”, Northwestern University Learning for Life Lectures, Chicago, IL, October 10, 2012.

43. Norgine, Inc., London, UK, April 17, 2012.

44. Roche, Inc., Basel, Switzerland, April 16, 2012.

45. “New Technologies for Colorectal Cancer Screening”, Colorectal Cancer Screening Working Group, Orlando, March 2012.

46. “Physical Markers and Universal Parameters in Cancer”, National Cancer Institute Think Tank on Integrating the Physical Science Perspective to Open a New Frontier in Oncology, Washington, D.C., Feb. 8, 2012.

47. “Cell Imaging at the Nanoscale: Detecting Nuclear Chromatin Alterations in Field Carcinogenesis”, AACR Conference on Frontiers in Cancer Prevention Research, Boston, MA, October 22-25, 2011.

48. “Partial wave spectroscopic microscopy: detecting alterations in cell nanoarchitecture in early carcinogenesis”, IEEE Photonics 2011, Arlington, VA, October 9-13, 2011.

49. “Clinical optical imaging & spectroscopy: Approaching the clinic”, Advances in Optics for Biotechnology, Medicine and Surgery XII, An ECI Conference Series, Naples, FL, June 5-8, 2011.

50. "Alterations in nuclear nanoscale architecture: optical imaging and the role in early carcinogenesis", NCI PS-OC Network Investigators’ Meeting, La Jolla, CA, April 10-12, 2011.

51. “Physics Meets Biology: Understanding the Role of Cell Nanoscale Structure in Carcinogenesis”, American Physical Society (APS) March Meeting, Dallas, TX, March 21-25, 2011.

52. “Scattering From Mass Fractals: Modeling and Observation”, SPIE Photonics West Conference, San Francisco, CA, Jan 22-27, 2011.

53. “Probing Cellular Nanoscale Organization”, Life Science Symposium, Swiss Federal Institute of Technology of Lausanne (EPFL), Lausanne, Switzerland, September 2-4, 2010.

54. “Optical Imaging: Insights into Cell Nanoarchitecture”, EECS Seminar, Northwestern University, May 12, 2010.

55. “Detecting Alterations in Cell Ultrastructure with Optical Imaging: Implications for Cancer Screening”, Frontiers of GI Research Conference, University of Illinois at Chicago, Department of Medicine, February, 2010.

56. “Detecting Alterations in Cell Ultrastructure with Optical Imaging: Implications for Cancer Screening”, Department of Physics, University of Wisconsin – Milwaukee, Milwaukee, December 11, 2009.

57. “Detecting Alterations in Cell Ultrastructure with Optical Imaging: Understanding the Role of Cell Morphology in Carcinogenesis”, Future of Light Symposium, Boston University Photonics Center, November 16, 2009.

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58. “Translating of Biophotonics Technologies into Clinical Practice: Challenges and Successes”, Coulter Biomedical Optics Industry-Academia Collaborative Meeting, Boston University, November 10, 2009.

59. “A Translational Biomedical Research Model”, Innovation Workshop Series, University of Chicago, October 29, 2009.

60. “Measuring cell nanoscale organization: partial wave spectroscopic microscopy”, IEEE-EMBS Annual Meeting, Minneapolis, September 2-6, 2009.

61. “Cancer Screening via Biophotonics: A “Remote Sensing” Approach”, University of Connecticut Health Center, April 9, 2009.

62. “Detecting alterations in cell nanoarchitecture with optical imaging”, University of California Irvine, April 2, 2009.

63. “Detecting alterations in cell nanoarchitecture with optical imaging”, University of Rochester, December 5, 2008.

64. “Optically sensing alterations in nanoscale cell architecture: a new paradigm for cancer screening”, Biotechnology Seminar, Northwestern University, October 29, 2008.

65. “Detecting alterations in cell nanoarchitecture with optical imaging: Implications for cancer detection”, Annual Optical Society of America Meeting, Frontiers in Optics (FiO)/Laser Science XXIV (LS) Conference, Rochester, NY, October 23, 2008.

66. “Optically sensing alterations in nanoscale cell architecture: a new paradigm for cancer screening”, Illinois Institute of Technology, Chicago IL, October 11, 2008.

67. “Surrogate Anatomic/Functional Sites for Evaluating Cancer Risk”, Physical Sciences & Oncology Mini-Symposium, Northwestern University, Chicago, IL, October 3, 2008.

68. “Alterations in Cellular Nanoarchitecture Is an Early Event in Carcinogenesis”, IBiS Seminar Series, Northwestern University, Chicago, IL, September 30, 2008.

69. “Optically sensing alterations in nanoscale cell architecture: a new paradigm for cancer screening”, University of Chicago Medical School, Chicago, IL September 18, 2008.

70. “Biophotonics for colon cancer screening”, Keynote speaker, Midwest Colon Cancer Symposium, September 13, 2008.

71. “Probing tissue architecture at submicron scale: seeing beyond histology”, 2008 Gordon Conference on Lasers in Medicine and Biology, Session on "Novel Techniques: Microscale to Nanoscale", New Hampshire, July 20-25th, 2008.

72. “Enhanced Backscattering for tissue characterization and diagnosis”, APS/USNC/URSI 2008, San Diego, CA, July 5-11, 2008.

73. "Cancer Screening via Biophotonics: A “Remote Sensing” Approach”, Clinical and Translational Research Seminar Series, Robert H. Lurie Comprehensive Cancer Center, Northwestern University, May 2008.

74. “Cancer Screening via Biophotonics: A “Remote Sensing” Approach”, FDA, April 2008.

75. “Cancer Screening via Biophotonics: A “Remote Sensing” Approach”, University of Chicago, Department of Chemistry Seminar, April 2008.

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76. “Low-Coherence Enhanced Backscattering as a colon cancer screening technology”, Midwest Biomedical Engineering Conference (MBEC), Chicago, IL, April 4, 2008.

77. “Rectal Coherent Backscattering Spectroscopy to screen for colon cancer”, Invited talk, American Institute for Medical and Biological Engineering (AIMBE) 17th. Annual Event, Washington D.C, February 20-22, 2008.

78. “Single-cell partial-wave spectroscopic microscopy: early detection of cancer”, Invited talk, SPIE - Photonics West, Symposium on Biomedical Optics, 2008, San Jose, CA, January 18-24, 2008.

79. “Cellular and Tissue Optical Measurements for the Detection of Colorectal Cancer – Does the Field Effect Exist”, Biomedical Imaging Research Opportunities Workshop, North Bethesda, Maryland, January 18, 2008.

80. “Detecting alterations in tissue nanoarchitecture with optical imaging: implications for cancer screening”, Chicago Biomedical Consortium, Chicago, IL, November 9, 2007.

81. "Analysis of nanoarchitecture of buccal epithelium for lung cancer screening", 15th EDRN Steering Committee Meeting, Ann Arbor, Michigan, September 17-19, 2007.

82. “Low coherence Enhanced Backscattering”, EMBS Annual Meeting, Lyon, France, August 2007.

83. “Partial wave microscopy: seeing beyond histopathology”, Clinical Pathology Meeting, Rosemont, IL, June 9-10, 2007.

84. “Preneoplasia: Predicting the Behavior of the Early Lesion”, The Educational Session, Annual Meeting of the American Association for Cancer Research, Los Angeles, CA, April 14, 2007.

85. Low-coherence Enhanced Backscattering: characteristics and applications for colon cancer screening”, SPIE - Photonics West, Symposium on Biomedical Optics, San Jose, CA, January 20-25, 2007

86. “Utilizing the field effect for cancer screening”, Northwestern University Cancer Center Board Meeting, Chicago, IL, November 2, 2006.

87. “Single cell partial wave spectroscopy: understanding alterations of intracellular nanoarchitecture in cancer”, Invited Talk, Annual Meeting of the Optical Society of America: Frontiers in Optics, Rochester, NY, October 8-12, 2006.

88. “Biophotonics Techniques in Detection of Early Colon Precancer: Using Colonic Cells as Reporters of Carcinogenesis”, NCI and DCTD Cancer Imaging Program Workshop on Imaging Science Development for Cancer Prevention and Preemption, Gaithersburg, MD, July 9-11, 2006.

89. “Low-coherence enhanced backscattering for biomedical applications”, Optical Society of America Summer Topical Meeting on Coherent Optical Technologies and Applications (COTA), Whistler, British Columbia, Canada, June 28-30, 2006.

90. “Screening for Pancreatic Cancer”, 2nd Annual Dinner of Alexander H. Steinkoler Foundation for Pancreatic Cancer Research, New York, NY, May 10, 2006.

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91. “Biophotonics for Cancer Screening: Can Star Trek-like Diagnostics Become a Reality?”, Northwestern University Alumni Association, May 3, 2006.

92. “Enhanced Light Backscattering for Non-invasice Early Detection of Colon and Pancreatic Cancer”, Oncology Imaging Symposium, Chicago, April 19, 2006.

93. “Enhanced Backscattering Spectroscopy”, Photomedicine Lecture Series, Wellman Center for Photomedicine, Massachusetts General Hospital, Boston, MA, November 2005.

94. “Detecting Pre-neoplastic Events in Colon Carcinogenesis with Optical Spectroscopy”, NCI-NTROI Workshop, November 2005.

95. “Noninvasive Screening for Colon Cancer Without Colonoscopy”, Mornings at McCormick Lecture Series, November 2005.

96. “Enhanced backscattering of light reveals the initial events in colon carcinogenesis”, 27th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Pre-conference workshop on Biomolecular Photonics and Imaging, Shanghai, China, September 2005.

97. “Detecting Pre-Neoplastic Events in Colon Carcinogenesis by Means of Low-coherence Enhanced Backscattering Spectroscopy”, Engineering Conferences International, Advances in Optics for Biotechnology, Medicine and Surgery, Copper Mountain, Colorado, July 2005.

98. “Intrinsic Sources of Optical Contrast are Better Than Extrinsic Sources for In Vivo Biomedical Applications”, Debate partner, Engineering Conferences International, Advances in Optics for Biotechnology, Medicine and Surgery, Copper Mountain, Colorado, July 2005.

99. “Imaging of Early Cancer”, Abbott, Inc., July 13, 2005.

100. “Detecting Invisible Precursors of Cancer with Scattered Light”, Biomedical Engineering Seminar, University of Illinois, Urbana-Champaign, April 2005.

101. “Detecting Invisible Precursors of Cancer with Low-coherent Backscattering Spectroscopy”, Biomedical Engineering Seminar, Tufts University, March 2005.

102. “Coherent Backscattering Spectroscopy: A new Technique for Tissue Diagnosis”, Biomedical Engineering Seminar, Duke University, March 2005.

103. “Understanding Pre-Neoplastic Events in Colon Carcinogenesis Using Elastic Light Scattering”, Biomedical Engineering and Electrical Engineering Colloquium, Boston University, February 2005.

104. “Early Detection, Diagnosis, and Therapy of Cancer”, Keynote Presentation, BiOS Hot Topics Session, BiOS Symposium at Photonics West, January 22, 2005.

105. “Detecting Invisible Precursors of Cancer with Scattered Light”, Illinois Microscopy Society, Chicago, IL, November 19, 2004.

106. “Understanding Pre-Neoplastic Events in Colon Carcinogenesis Using Light Scattering”, Biomedical Engineering Seminar, University of Arizona, November 2004.

107. “Coherent Backscattering Spectroscopy: A new Technique for Tissue Diagnosis”, BMES 2004 Annual Meeting, Philadelphia, PA, October 13-16, 2004.

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108. “Detection of Pre-Dysplastic Stages of Colon Carcinogenesis Using Elastic Light Scattering Fingerprinting”, Fourth Inter-Institute Workshop on Optical Diagnostic Imaging from Bench to Bedside at the National Institutes of Health, September 20-22, 2004.

109. “Coherent Backscattering Spectroscopy: A New Technique for Tissue Diagnosis”, IEEE/EMBS Conference, San Francisco, CA, September 1-4, 2004.

110. “Detection of Pre-Dysplastic Stages of Colon Carcinogenesis Using Elastic Light Scattering Fingerprinting”, NSF/NIH/NASA Image-Guided Interventions (IGI) for Medical Applications Workshop, Bethesda, MD, May 13-14, 2004.

111. “Increased Mucosal Blood Supply is an Early Preneoplastic Marker in Colon Neoplasia”, Distinguished Abstract, Plenary Session, Digestive Disease Week (The American Gastroenterological Association), Orlando, May, 2004.

112. “Detection of Pre-Dysplastic Stages of Experimental Colon Carcinogenesis Using Light Scattering Fingerprinting”, Preventive GI Oncology Conference, Northbrook, IL, October 25, 2003.

113. “Diagnosis of the Earliest Stages of Colon Carcinogenesis Using Light Scattering “Fingerprinting”, Biological Sciences Seminar Series, Harvard School of Public Health, Boston, MA, September 2, 2003.

114. “Light Scattering Spectroscopy and Imaging of the Initial Stages of Carcinogenesis”, CUBIC, Chicago, IL, March 7, 2003.

115. “How to Cheat the Diffraction Limit: Far-Field Measurement of Nanometer Structures”, Spectroscopy at Nanoscale Seminar, Massachusetts Institute of Technology, Cambridge, MA, January 27, 2003.

116. “Spectroscopic Optical Imaging”, BMES Annual Meeting, Houston, TX, October, 2002.

117. “Light Scattering Spectroscopy and Its Potential Applications in Clinical Medicine”, Illinois Innovation Initiative, West Chicago, IL, December 14, 2001.

118. “Optical Spectroscopic Imaging: From Structural Analysis to Early Cancer Detection”, Technology Update, Evanston, IL, December 6, 2001.

119. “Functional Imaging of Tissue Morphology with Light Scattering Spectroscopy”. Invited Speaker, American Physical Society Annual Meeting, Seattle, Washington, March 2001.

120. “Biomedical Imaging with Light Scattering Spectroscopy: a New Tool for Early Cancer Detection”, Invited Speaker, Biomedical Engineering Seminar Series, Northwestern University, February 2001.

121. “Functional Imaging of Early Cancer with Light Scattering Spectroscopy”, BIOS 2001, Photonics West, SPIE Conference, San Jose, CA, January 2001.

122. “Functional Biomedical Imaging with Scattered Light”. Invited Speaker, Modern Optics and Spectroscopy Seminar Series, Massachusetts Institute of Technology, Cambridge, Massachusetts, September 2000.

123. “Functional Imaging with Polarized Light Scattering Spectroscopy”. Invited Speaker, Optical Imaging Festival, Massachusetts Institute of Technology, Cambridge, Massachusetts, March 2000.

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124. “Early Detection of Precancer Using Polarized Light Scattering Spectroscopy”, Invited Speaker, Press Conference at American Physical Society Meeting, Minneapolis, Minnesota, March 2000.

125. “Fourier Transform Reflectance Spectroscopy for Non-invasive Diagnosis of Dysplasia”. Harvard-MIT Biomedical Engineering Seminar Series, Cambridge, Massachusetts, February 1998.

126. “Fourier Transform Reflectance Spectroscopy: A New Method of Dysplasia Diagnosis”. Invited Speaker, Lester Wolfe Workshop on Biomedical Optics, Cambridge, Massachusetts, March 1997.

127. “Determination of Polarization of Vacuum-Ultraviolet Radiation by Fluorescence and Probe-Beam Techniques”. Invited Speaker, International Workshop on Solar Polarization, St. Petersburg, Russia, 1995.

PROFESSIONAL AND UNIVERSITY SERVICE Symposia Organization:

Conference Chair, Telluride Workshop on Physical Genomics and Transcriptional Engineering, Telluride, CO, February 25- March 1, 2019.

Conference Chair, Biophotonics, Biology and Biophysics: Convergence (B3C) II, Photonics West, San Francisco, California, February 2019.

Conference Chair, H Foundation Basic Science Symposium: The Physics of Cancer Epigenetics, Northwestern University, Chicago, IL, April 20, 2018

Conference Chair, Biophotonics, Biology and Biophysics: Convergence (B3C) II, Photonics West, San Francisco, California, January 2018.

Conference Chair, Biophotonics, Biology and Biophysics: Convergence (B3C) II, Photonics West, San Francisco, California, February 2017.

Panel Leader, Optical Nanoscale Imaging: Unraveling the Chromatin Structure-Function Relationship, AAAS Annual Meeting, Boston, MA, February 2017.

Program Committee, 5th International Conference on Photonics, Optics and Laser Technology, Porto, Portugal, February 2017.

Advisory Board, Point of Care Diagnostics World Congress, San Diego, CA, September 2016.

Program Committee, OSA Biomedical Optics Congress, Hollywood, FL, April 2016. Conference Chair, Biophotonics, Biology and Biophysics: Convergence (B3C), Photonics

West, San Francisco, California, February, 2016. Advisory Board, Point of Care Diagnostics World Congress, San Diego, CA, September

2015. Conference Chair, Biomedical Applications of Light Scattering IX, Photonics West, San

Francisco, California, February, 2015. Advisory Board, Point of Care Diagnostics World Congress, San Diego, CA, September

2014. General Chair, Biomedical Optics Congress, Miami, FL, May 2014. Conference Chair, Biomedical Applications of Light Scattering VII, Photonics West, San

Francisco, California, February, 2014.

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Conference Chair, Biomedical Applications of Light Scattering VI, Photonics West, San Francisco, California, January, 2013.

Organizer, Colorectal Cancer Screening Working Group, Orlando, March 2012. Program Chair, Optical Spectroscopy, OSA BIOMED, Miami, FL, April 29-May 2, 2012. Co-Chair, Early Cancer Detection, World Molecular Imaging Congress (WMIC), San

Diego, CA, September 7-10, 2011. Program Committee, ECI Advances in Optics for Biotechnology, Medicine and Surgery

XII, Chair for Clinical Optical Imaging and Spectroscopy session, Naples, Florida, June 5-8, 2011.

Conference Chair, Biomedical Applications of Light Scattering V, Photonics West, San Francisco, California, January, 2012.

Conference Chair, Biomedical Applications of Light Scattering IV, Photonics West, San Francisco, California, January, 2011.

Conference Chair, Biomedical Applications of Light Scattering III, Photonics West, San Francisco, California, January, 2010.

Program Committee, Bio-Optics in Clinical Application, OSA Biomed Topical Meeting, Miami, April 11-15, 2010.

Mini-symposium on Ultra-sensitive Biomedical Sensing Technologies, IEEE-EMBS Annual Meeting, Minneapolis, September 2-6, 2009.

Program Committee, Novel Optical Instrumentation for Biomedical Applications Subconference at the European Conference on Biomedical Optics, Munich, June 2009.

Conference Chair, Biomedical Applications of Light Scattering III, Photonics West, San Jose, California, January, 2009.

Conference Chair, Biomedical Applications of Light Scattering II, Photonics West, San Jose, California, January, 2008.

Program Committee, LEOS Annual Meeting, Florida, October 24, 2007. Conference Chair, Biomedical Applications of Light Scattering I, Photonics West, San

Jose, California, January 20-25, 2007. Committee Member, LEOS Annual Meeting, Montreal, QC, Canada, October 29 –

November 2, 2006. Program Committee for the Optical Society of America Biomedical Optics Meeting:

Optical Spectroscopic Imaging & Diagnostics, April, 2006. Program Committee for Biophotonics, Lasers and Electro-Optics Society (LEOS) Annual

Meeting, Montreal, Canada, October-November, 2006. Chair, Subcommittee for Medical and Biological Applications, CLEO 2006. Technical Program Committee for Medical and Biological Applications, CLEO,

Baltimore, MD, May 23-27, 2005. Session Chair:

New Technologies in Medical Diagnostics, Biophysics, Biology and Biophotonics III: the Crossroads, Photonics West, San Francisco, California February 2018. Theory I, Biomedical Applications of Light Scattering VIII, Photonics West, San

Francisco, California, February, 2015. Spectroscopy of Elastic Light Scattering, Biomedical Optics and 3D Imaging, Miami FL,

USA, May 2, 2012.

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Clinical optical imaging & spectroscopy: Approaching the clinic, Advances in Optics for Biotechnology, Medicine and Surgery XII, An ECI Conference Series, Naples, FL, June 5-8, 2011.

Nanoscale Measurements, Biomedical Applications of Light Scattering IV, Photonics West, San Francisco, California, January, 2010.

Enhanced Backscattering, Biomedical Applications of Light Scattering IV, Photonics West, San Francisco, California, January, 2010.

Recent Advances in Translational Biophotonics and Nanophotonic Imaging Technologies, IEEE-EMBS Annual Meeting, Minneapolis, September 2-6, 2009.

Numerical Simulation Studies, Biomedical Applications of Light Scattering III, Photonics West, San Jose, California, January, 2009.

In Vitro Applications, Biomedical Applications of Light Scattering III, Photonics West, San Jose, California, January, 2009.

Spectroscopy of Biomolecular Processes, Frontiers in Optics (FiO)/Laser Science XXIV (LS), Rochester, NY, October 2008.

Biomedical Applications of Light Scattering, Photonics West, San Jose, California, 2007. Spectroscopic Signatures, OSA Annual Meeting, 2006. Molecular and Cellular Sensing, CLEO, 2006. Scattering and Absorption, CLEO, 2006. Biomedical Optics: Living on the Edge, CLEO, 2006. Light Scattering Spectroscopy and Imaging, CLEO, May 23-27, 2005. Tissue Optical Diagnostics, BMES 2004, October 16, 2004. Diffuse Optical Tomography and Spectroscopy, Frontiers in Optics/Laser Science XIX

Conference, October 5 - 9, 2003. Editorial Service:

Associate Editor, Science Advances (2017 - present) Associate Editor, Biomedical Optics Express (2012) Editor, Fundamentals of Biophotonics, CRC Press (expected completion, 2018). Editor, Biomedical Applications of Light Scattering, McGraw Hill Publishing (2009). Honorary editorial board, Reports in Medical Imaging (2009). Guest Editor, IEEE Journal of Selected Topics in Quantum Electronics, Special Issue on

Biophotonics (2007). Co-editor, Disease Markers, Special Issue on Spectroscopic Markers (2006). Guest Editor, Journal of Biomedical Optics (2005).

Grant Review: Chartered Member of NIH Biomedical Imaging Technology (BMIT) Study Section (September 2010 – 2014)

Other Grant Review: NSF: STC Site Visit (October 2018) NSF: CAREER Review Panel, Division of Bioengineering, (September 2017) NSF: Biophotonics Panel, CBET (January 2015) NSF: CAREER Review Panel, Division of Bioengineering, (October 2014) NSF: CAREER Review Panel, Division of Bioengineering, (September 2013) NSF: Biophotonics Panel, CBET (December 2012) NSF: Physical Sciences and Cancer (May 2012)

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NSF: CAREER Review Panel, Division of Bioengineering, (October 2011) NSF: Biophotonics Review Panel, Division of Bioengineering, (December 2010) NSF: CAREER Review Panel, Division of Bioengineering (2010) NSF: Interdisciplinary Biocluster Panel, (February 2010) NSF: Biophotonics Review Panel, Division of Bioengineering, (December 2009) NSF: Biophotonics Review Panel, Division of Bioengineering, (May 2009) NSF: Biophotonics Review Panel, Division of Bioengineering, (Fall 2008) NSF: Biophotonics Review Panel, Division of Bioengineering, (Spring 2008) NSF: CAREER Review Panel, Division of Bioengineering (2007) NSF: Biophotonics Review Panel, Division of Bioengineering (2007) NSF: Biophotonics Review Panel, Division of Bioengineering (2006) NSF: Biomedical Imaging/Optical SBIR/STTR panel (2006) NSF: Biophotonics Review Panel, Division of Bioengineering (2005) NSF: CAREER Review Panel, Division of Bioengineering (2005) NSF: Biophotonics Review Panel, Division of Bioengineering (2004) NSF: CAREER Review Panel, Division of Bioengineering (2004) NSF: Nanotechnology Review Panel (2003) NSF: CAREER Review Panel, Division of Bioengineering (2003) NIH: NCI Provocative Questions Review (October 2018) NIH: Instrumentation and Systems Development (ISD) Study Section (October 2018) NIH: Biomedical Imaging Technology (BMIT) Study Section (February 2018) NIH: Instrumentation and Systems Development (ISD) Study Section (February 2018) NIH: Instrumentation and Systems Development (ISD) Study Section (October 2017) NIH: Instrumentation and Systems Development (ISD) Study Section (June 2017) NIH: Biomedical Imaging Technology (BMIT) Study Section (September 2016) NIH: Biomedical Imaging Technology (BMIT) Study Section (February 2016) NIH: Chair, PS-OC U01 Study Section (July 2015) NIH: Biomedical Imaging Technology (BMIT) Study Section (February 2014) NIH: Biomedical Imaging Technology (BMIT) Study Section (June 2013) NIH: P41 Site Visit (November 2012) NIH: Biomedical Imaging Technology (BMIT) Study Section (October 2012) NIH: Clinical and Translational Imaging Applications Study Section (June 2012) NIH: Biomedical Imaging Technology (BMIT) Study Section (February 2012) NIH: Biomedical Imaging Technology (BMIT) Study Section (October 2011) NIH: Advanced In Vivo Imaging to Understand Cancer Systems (NCI) (June 2011) NIH: Biomedical Imaging Technology (BMIT) Study Section (February 2011) NIH: Biomedical Imaging Technology (BMIT) Study Section (October 2010) NIH: Bioengineering Research Partnership (BRP) (June 22, 2010) NIH: RC4 and T-R01 Panels (April-May 2010) NIH: Biomedical Imaging Technology (BMIT) Study Section (October 2009) NIH: Novel Imaging Study Section (SBIB-J) (June 2009) NIH: Challenge Grants Review (May 2009) NIH: Biomedical Imaging Technology (BMIT) Study Section (October 2008) NIH: Quick Trials Study Section (October 2008) NIH: Novel Imaging Study Section (SBIB-J) (June 2008) NIH: Cellular and Molecular Imaging Centers (November 2007)

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NIH: Novel Imaging Study Section (SBIB-J) (October 2007) NIH: Biomedical Imaging Technology (BMIT) Study Section (September 2007) NIH: Training grants (July 2007) NIH: Novel Imaging Study Section (SBIB-J) (June 2007) NIH: Study Section SBIB-P(02) (June 2007) NIH: Novel Imaging Study Section (SBIB-J) (March 2006) NIH: Novel Imaging Study Section (SBIB-J-1) (February and November 2006) NIH: Biomedical Imaging Technology (BMIT) Study Section (February and October

2006) NIH: Novel Imaging Study Section (SBIB-J-1) (2005) NIH: Centers of Cancer Nanotechnology Excellence (CCNEs) Special Emphasis Study

Section (2005) NIH: Biomedical Imaging Technology (BMIT) Study Section (2005) NIH: SBIB Study Section (2005) NIH: Diagnostic Imaging (DMG) Study Section (2004) NIH: Biomedical Imaging Technology (BMIT) Study Section (2004) NIH: Sciences Special Study Section, National Institute of General Medical (2004) The Indiana 21st Century Research and Technology Fund (2009) Science Foundation Ireland Cancer Research UK (UK) The Welcome Trust (UK): Molecular and Cell Biology Scientific Programme Association for International Cancer Research (UK) University of North Texas Excellence Fund CCSG Program, Northwestern University NUCATS, Northwestern University The Technology Foundation STW, Netherlands Organization for Scientific Research,

NWO, and the Dutch Ministry of Economic Affairs Book Peer-review:

Physiology for Engineering Students (Joseph Feher, Elsevier) Femtosecond Biomedical Optics (Cambridge University Press) Encyclopedia of Medical Devices and Instrumentation (John Webster, edt., Wiley, Inc.)

Journal Peer-review:

Nature Nanotechnology, Nature Medicine, Nature Materials, PNAS, Optics Letters, Applied Optics, Journal of Biomedical Optics, Journal of Physics D: Applied Physics, Journal of Optical Society of America, Journal of Optics A: Pure and Applied Optics, Biotechnology Progress, Physics in Medicine and Biology, Lasers in Surgery and Medicine, Optics Express, Technology in Cancer Research and Treatment, Journal of Orthopaedic Research, Review of Scientific Instruments, TPDSci: Journal on selected Topics of Particle and Dispersion Science.

Professional Societies:

Optical Society of America, American Physical Society, International Society for Optical Engineering, American Institute for Medical and Biological Engineering (AIMBE)

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Professional Membership: Associate Member, Network for Translational Research (NTR) (2009-present) National Institutes of Health Early Detection Research Network (2004-present) Network for Translational Research Optical Imaging (NTROI): Optical Spectroscopy for Management of Cancer Treatment (2004-2009)

Board Membership and Other Professional Service: The Steinkoler Pancreatic Cancer Foundation, Member of the Board (2008-present) AIMBE Advocacy Committee (2010-present)

Consulting: Johnson & Johnson, Inc. Morningside Evaluations and Consulting Round Table Group Guidepoint Global Advisors

Northwestern University Service:

Promotion and Tenure Committee, McCormick School of Engineering and Applied Sciences (2010-present)

Biomedical Engineering Graduate Committee (2010-present) One Northwestern Committee (2007) Representative of McCormick School of Engineering and Applied Sciences, Admission

Committee, Honors Program in Medical Education (2004-2006) Chair of the Graduate Program Committee (2006-present) Graduate Program Committee (2005-2006) Programming Team, Proteomics and Nanobiotechnology Facility (2005-present) Biomedical Engineering Department-Electrical and Computer Engineering Department

Faculty Search Committee (2005) Academic Standing Committee (2002-2004)

TEACHING

BME 302/402: Systems Physiology: Cardiovascular and Respiratory Physiology. BME 333: Modern Optical Microscopy (new course, first offered in fall, 2001). BME 495: Advanced Physical and Applied Optics (new course, first offered in spring, 2002).

POSTDOCTORAL FELLOW AND STUDENT SUPERVISION

Postdoctoral Fellow Supervision: Xu Li, Ph.D. (2003-2005), currently tenure-track Assistant Professor, Biomedical

Engineering Department and Electrical and Computer Engineering Department, Northwestern University.

Young Kim (2005-2007), currently tenure-track Assistant Professor, Biomedical Engineering Department, Purdue University.

Kun Chen, Ph.D. (2002-2004), currently Assistant Professor at Shanghai Institute of Optics and Fine Mechanics, Shanghai, China.

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Snow Tseng, Ph.D. (2005), currently tenure-track Assistant Professor at Taiwan University.

Jianmin Gong, Ph.D. (2003-2005) Soon-Cheol Kong, Ph.D. (2007-2009) Alexander Heifetz (2005-2008), Research Scientist, Argonne National Laboratory Prabhakar Pradhan (2005-2013), currently tenure-track Assistant Professor at University

of Memphis Jeremy Rogers (2007-2013), currently tenure-track Assistant Professor at University of

Wisconsin-Madison Ilker Capoglu (2007-2012), currently Scientific Advisor at Halliburton Hariharan Subramanian (2009-2012) currently Research Assistant Professor at

Northwestern University Vladimir M. Turzhitsky (2009-2010), currently Instructor at Harvard University Seungmoo Yang (2009-2012) Teng Meng Tan (2011-2012), currently Electrical Engineer at University of Calgary Andrew Gomes (2013) Ji Yi (2013-2015), currently Assistant Professor, Boston University Medical School Yolanda Stypula (2014-2015), currently Senior Scientist at Promega Qin Miao (2014-2015) Andrew Radosevich (2014-2015), currently Research Scientist at AbbVie Sebastian Thompson (2014-2016) Lusik Cherkezyan (2014-2018) Greta Wodarcyk (2018 – present)

Clinical Fellows Training: Vani Konda, M.D., University of Chicago Medical School (2008-present) Visiting Scientists Yuki Shono, Olympus Corporation (2011-2013)

Yoko Horino, Olympus Corporation (2013) Graduate Student Supervision:

Young Kim (Ph.D., 2005), currently tenure-track Assistant Professor, Biomedical Engineering Department, Purdue University.

Yang Liu (Ph.D., 2006), currently tenure-track Assistant Professor, University of Pittsburgh

Shiv Tumkur (M.S., 2003) Amit Sharma (M.S., 2004) Michael Siegel (M.S., 2005) Zhigang Chen (Ph.D., 2005) Bo Liu (M.S., 2007) Hariharan Subramanian (Ph.D., 2009), currently Research Assistant Professor at

Northwestern University Vladimir M. Turzhitsky (Ph.D., 2009), currently Instructor at Harvard University Valentina Stoyneva (M.S., 2012) Wendy Yip (Ph.D., 2012), currently Data Scientist at The Data Incubator Charles Maneval (M.S., 2013), currently Research & Test Engineer at SpineFrontier

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Andrew Gomes (Ph.D., 2013), currently Medical Writer at Ashfield Healthcare Communications

Nikhil Mutyal (Ph,D., 2013), currently Lifesciences Business Development Specialist at AVEO Oncology

Ji Yi (Ph.D., 2013), currently Assistant Professor, Boston University Medical School Dhwanil P. Damania (M.S., 2009; Ph.D., 2013), currently R&D Biomedical Engineer at

Vital Connect, Inc. Lusik Cherkezyan (Ph.D., 2014), currently Senior Scientist at GE Healthcare Yolanda Stypula (Ph.D., 2014), currently Senior Scientist at Promega Andrew Radosevich (Ph.D., 2014), currently Research Scientist at AbbVie Sarah K. Ruderman (Ph.D., 2015) Ankit Gandhi (M.S., 2015), currently Assay Development Research Associate at T2

Biosystems Scott Young (M.S., 2015) Taylor Graff (M.S., 2016) Alexis Kendra (M.S., 2016) Ron Ellis (M.S., 2016) Andrew Stawarz (MS, 2017) Yuting Dou (MS, 2017) John Chandler (Ph.D., 2016) Di Zhang (Ph.D., 2018) Xiang Zhou (MS, 2018) Mary Miller (MS, 2018) Luay Almassalha (Ph.D./M.D., 2018) Greta Bauer (Ph.D., 2018) Hanlin Mok (MS, expected 2020) Adam Eshein (Ph.D., expected 2019) Scott Gladstein (Ph.D., expected 2019) Wenli Wu (Ph.D., expected 2019) Graham Spicer (Ph.D., expected 2019) James Winkelmann (Ph.D., expected 2019) Rongrong Liu (Ph.D., expected 2019) Yue Li (Ph.D., expected 2019) Aya Eid, (Ph.D., expected 2020) Jane Frederick (Ph.D., expected 2022) Ranya Virk (Ph.D., expected 2022) Vasundhara Agrawal (Ph.D., expected 2022) Sreyesh Satpathy (Ph.D., expected 2023) Millicent Lin (Ph.D., expected 2023)

Undergraduate Student Supervision: Tina Amirtha, Daniel Saddawi-Konefka, Shawn Liu, Max Choi, Tarak Shah, Lawrence Chang, Hyung-Joo Yoon, Kenneth Liu, Thomas Kluz, Parmede Vakil, Robin Brusen, Catherine Cheng, Min Kim, Josphen Young, David Raslau, Vladimir Turzhitsky, Min Kim, Kevin Huang, Nikhil Mutyal (visiting pre-doctoral fellow), Soumya Bonthu, Nicholas Deep, Jay Hoogheem, Munira Karim, David Magill, James Spadaro III, Daniel

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Balikov, Antonio Roy Webb, Michael J Yung, Shivaprasad Daram, N. Rishall, Vishal S. Parikh, Aditya K. Thasan, Arun Ahuja, Andrew Radosevich, Sameer Maheshwari, Todd McCullough, Aditya Gupta, Vivek Patel, Samantha Strasser, Curie Chang, Yuanija Zhu, Dennis Blurer, Craig White, Daniel Park, Rohit Subramanian, Akhilendra Vohra, Charles Hwang, Johny Sun, Alfredo Osorio, Frank Cummins, Taylor Lee, Benjamin Tiano, Elizabeth Horcher, Varun Gupta, Arpa Mukherjee, Zita Hubler, Casey Blaha, Nick Boffi, Kellie Perkins, Brian Kennedy, Blake Burnstad, Joseph Lee, Anusha Vadlamanu, Molly Bird, Leah Bowen, Billy Frese, Christine Osorio, Michael Chen, Katerina Maria Cheronis, Ambuj Bhalla, Kim Hoang, Priyanka Mathur, Shoham Benmelech.

Thesis Committee:

Young Kim (Ph.D., 2005), Zhigang Chen (Ph.D., 2005), Yang Liu (Ph.D., 2006), Vladimir M. Turzhitsky (M.S., 2006), Abhishek Mathur (Ph.D., 2007), Michael Siegel (M.S., 2005), Snow Tseng (Ph.D., 2005), Marissa Darmoc (M.S., 2005), Wendy Yip (Ph.D., 2012), Olga Lyandres (Ph.D.), Ke Ma (Ph.D., 2013), Kvar Black (Ph.D., 2012), German Picasso (Ph.D., 2014), Wenzhong Liu (Ph.D., 2017), Sean Allen (Ph.D., 2018).

SELECTED MEDIA COVERAGE

Title: Racing Against Cancer: New Efforts to Save Lives with Early Detection Source: Chicago Tribune Posted: May 21, 2018 Title: Scientists Target Cancer’s ‘Achilles Heel’ to Stop Therapy Resistance Source: WTTW – Chicago Tonight (Television Broadcast) Posted: November 9, 2017 Title: New DNA Imaging Technique Breaches 10-Nanometer Resolution Threshold, Becomes First To See DNA “Blink”. Source: International Business Times Posted: February 20, 2017 Title: Enhancing Molecular Imaging with Light Source: Science Daily Posted: July 25, 2016 Title: Six New Medical Technologies Worth Watching Source: Wall Street Journal Posted: June 27, 2016 Title: Using Data to Protect Coral Reefs from Climate Change Source: Science Daily Posted: April 13, 2016 Title: Metastatic Cells Colonize Implantable Scaffold in Mice Source: Oxford University Press Blog

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Posted: February 2, 2016 Title: Prognosis: Proportionate Response Source: Nature Posted: December 15, 2015 Title: New Technique Might Identify Dangerous Prostate Cancers Source: Chicago Sun-Times Posted: April 10, 2015 Title: Nanotechnology Shows Promise for More Accurate Prostate Cancer Screening, Prognosis Source: Medical Xpress Posted: March 16, 2015 Title: First Screening Method to Detect Presence of Ovarian Cancer Source: NSF ‘Science Now’ Posted: May 23, 2013 Title: Nanotechnology May Aid Ovarian Cancer Detection Source: Chicago Tribune Posted: May 15, 2013 Title: Extra Scrutiny for ‘Grandee’ Grantees Source: Nature Posted: February 20, 2012 Title: Breakthrough in Early Cancer Detection Source: NSF Science Nation & PBS News Hour Posted: January 9, 2012 Title: Combined Technologies Offer Promise for Detecting Colon Cancer in Women Source: NSF News, U.S. News & World Report Posted: July 20, 2010 Title: New method shines light on pancreatic cancer screening Source: Chicago Tribune Posted: February 23, 2009 Title: Shining light on pancreatic cancer Source: NSF, Year in News, 2007 Posted: August 1, 2007 Title: Lighting up cancer: Experimental test for colon cancer Program: ABC 7 News, 10:00 pm Station: ABC

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Airdate: April 5, 2006 Subject: New Test for Colon Cancer Program: CBS News, 5:00 pm Station: CBS Airdate: July, 2006 Subject: Colon Testing Made Easier Program: NBC News, 4:30 pm and 10 pm Station: NBC Airdate: June 28, 2006 The story also aired by 180 NBC affiliates. Title: “Shining a light on colon testing. Cheap, comfortable screening technique.” Newspaper: HealthBeat section in Tempo, Chicago Tribune Publication date: June 13, 2006. Subject: Colon cancer research Program: WGN News at Nine Station: WGN Airdate: May 19, 2006 Media summary for publication of the development of partial wave spectroscopic (PWS) microscopy and its application for pancreatic cancer diagnosis in Optics Letters (February, 2009): NSF News: Feature # 1; Current, NSF Monthly News Letter (August 2009); Chicago Tribune; over 40 news articles reaching an audience of 1.4 million. Media summary for publication of pancreatic cancer screening by biophotonics in Clinical Cancer Research (August 1, 2007): News National Science Foundation News, Forbes, Scientific American, U.S. News & World Report, WebMD, Los Angeles Daily News, Science Daily, United Press International, CNN, Photonics.com, yahoo.com news. Media summary for publication of the development of partial wave spectroscopic (PWS) for lung cancer screening in Cancer Research (October, 2010): NSF News: Feature # 3 “Cheek Swab May Detect Lung Cancer”, Scientific American, US News & World Report, and multiple other media reports.