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Adaptive Vs. Innate Immunity Innate (local response) Adaptive (systemic response) Response time Min"hrs (fast) D"wks (slow) Level of response Fixed Varies Specific? NO YES Memory? NO YES + byPAMPs binding to TLRs (polysaccharides & NTs) YES (specific for 1 epitope (protein or AA)) Where Rs are made In germline Made randomly What species? ALL Vertebrates

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  • Adaptive Vs. Innate Immunity Innate (local response)

    Adaptive (systemic response)

    Response time Min"hrs (fast) D"wks (slow)

    Level of response Fixed Varies

    Specific? NO YES

    Memory? NO YES

    + by PAMPs binding to TLRs (polysaccharides & NTs)

    YES (specific for 1 epitope (protein or AA))

    Where Rs are made In germline Made randomly

    What species? ALL Vertebrates