daniel n. sauderassets-powerstores-com.s3.amazonaws.com/data/org/15182/media/doc/... · daniel n....

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CURRENTPOSITIONSDermatologist MagentaHealth,Toronto,OntarioPfizerDermatologyAdvisorBoard 2017-CelgeneConsultant2015-PresentMedicalDirectorNeostrataUSA PrincetonNJ2010-PresentAdjunctProfessor DepartmentofMedicine(DivisionofDermatology)2013-2016 UniversityofOttawaSeniorConsultant HalozymeTherapeuticsInc.,SanDiego,California2009-Present

IMMEDIATEPASTPOSITIONS Dermatologist Princeton,NJHeadofDermatology, PrincetonUniversityHospital2010-2013Clinicalprofessor RobertWoodJohnsonSchoolofMedicine2005-2010VicePresidentClinicalDevelopment 2007-2008 ExcaliardPharmaceuticals,Carlsbad,CaliforniaSeniorVicePresident ClinicalDevelopment2005-2007 Dr.Reddy’sLaboratoriesInc,Bridgewater,NewJerseyNoxellProfessor&Chairman DepartmentofDermatology2001-2005 JohnsHopkinsUniversitySchoolofMedicine Baltimore,MarylandProfessor&Chief DivisionofDermatology,DepartmentofMedicine

CurriculumVitaeDANIELN.SAUDERMD,FRCP(C),FACPTORONTO,ONTARIO

[email protected]•(m)908-507-1770

DanielN.Sauder,MD,FRCP(C),FACP

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1990-2001 UniversityofToronto Toronto,Ontario,Canada EDUCATIONANDTRAINING 1979-83 Visiting Associate, Dermatology Branch, NCI, National Institutes of

Health, Bethesda, Maryland, U.S.A. 1977-79 Dermatology Residency, Cleveland Clinic, Cleveland, Ohio 1975 M.D. McMaster University, Hamilton, Ontario 1972 Master of Arts, Mathematics, York University, Toronto, Ontario 1971 Bachelor of Arts, Honors Mathematics, York University, Toronto, Ontario MEDICALLICENSING1991 FACP Fellow, American College of Physicians 1980 FRCPC Fellow of Royal College of Physicians & Surgeons-Canada 1983 FAAD Fellow, American Academy of Dermatology 1980 DABD Diplomat, American Board of Dermatology 1978 ABIM American Board of Internal Medicine 1977 FLEX Federation Licensing Examination 1975 LMCC Licensing Medical Council of Canada


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CURRICULUM VITAE CONTENTS I.PROFESSIONALACTIVITES 4

A.PROFESSIONALEXPERIENCE 4

B.SCIENTIFICBOARDS 5

C.BOARDOFDIRECTORS 5

D.EDITORIALBOARDS 6

E.INSTITUATIONALADMINISTRATIVEAPPOINTMENTS 6

F.PROFESSIONALSOCIETIES 7

G.RECOGNITION,AWARDSANDHONORS 7

H.MANUSCRIPTREVIEWS 8

I.EXTERNALGRANTREVIEWS 8

J.CONSULTING 8

II.RESEARCHACTIVITIES 9

A.INVENTIONS,PATENTSANDCOPYRIGHTS 9

B.PUBLICATIONS 9

Peer-ReviewedArticles 9

Peer-ReviewedClinicalReviews 22

LettersandEditorials 24

BookChapters 25

Abstracts 28

C.GRANTSUPPORT 43

Peer-ReviewedOperatingGrants(PrincipalInvestigator) 43

Peer-ReviewedOperatingGrants(Co-Investigator) 43

Non-PeerReviewedGrantSupport 46

D.CLINICALTRIALS 52

III.EDUCATIONALACTIVITIES 58

A.VISITINGPROFESSORLECUTRES,INVITEDLECTURESANDPANELS 58

B.EDUCATIONALMENTORING 62

Postdoctoral&ResearchFellows 62

GraduateStudents 63

GraduateStudents'SupervisoryCommittee 63

MscSupervisor 63

Immunology450Supervisor: 63


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I.PROFESSIONAL ACTIVITES

A. PROFESSIONAL EXPERIENCE 2009–Present SeniorConsult,HalozymeTherapeuticsInc.Mar07-Present Consultant,JohnsonandJohnsonNov05-Dec07 Consultant,RegulatoryAssociatesInc.Jul05-Jun07 SeniorVicePresident,ClinicalDevelopment Dr.Reddy’sLaboratories,Inc.;Bridgewater,NewJerseyJul04-Jun05 Professor DepartmentofDermatology,SchoolofMedicine JohnsHopkinsUniversity Baltimore,MarylandDec05–Present ClinicalProfessor,DepartmentofMedicine, UniversityofMedicineandDentistryofNewJerseyJul01-Jun04 NoxwellProfessor&Chairman DepartmentofDermatology,SchoolofMedicine JohnsHopkinsUniversity Baltimore,MarylandOct90-Jul01 ProfessorandChief DivisionofDermatology,DepartmentofMedicine UniversityofToronto,Toronto,Ontario,CanadaJul92–Jul01 Professor,InstituteofMedicalScience DepartmentofMedicalBiophysics UniversityofToronto,Toronto,Ontario,Canada1994-2001 Professor,DepartmentofImmunology UniversityofTorontoJul93–Mar96 Director,GeneralResearchProgram, SunnybrookHealthScienceCentre Toronto,Ontario,CanadaJul90–Sep90 Professor,DivisionofDermatology DepartmentofMedicine,McMasterUniversity Hamilton,Ontario,Canada


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Dec85–Jun90 AssociateProfessor,DivisionofDermatology DepartmentofMedicine,McMasterUniversity Hamilton,Ontario,CanadaMay82-Dec85 AssistantProfessor,DivisionofDermatology DepartmentofMedicine,McMasterUniversity Hamilton,Ontario,Canada

B. SCIENTIFIC BOARDS 2005-Present AmericanMelanomaFoundation2005-2007 QLTVancouver,Canada1999 InternationalAdvisoryBoard,InternationalWorkshopon

LangerhansCells1999-2001 ChairmanoftheCommitteeonFinances; TheSocietyofInvestigativeDermatology1995-2001 ScientificAdvisoryBoard,AeternaLesLaboratories1995-1996 BoardofDirectors,SeragenBiopharmaceuticalsLtd.1992-1995 CanadianSocietyforInvestigativeDermatology(President)1995-2000 CanadianSocietyforInvestigativeDermatology(Secretary-

Treasurer)1992-1995 BoardofDirectors,CanadianSocietyforDermatologicSurgery1991-1993 BoardofScientificCounselors-NationalInstitutesofHealth, Bethesda,Maryland1991-Present CentreforAlternativestoAnimalTesting(CAAT),JohnsHopkins

University,BaltimoreMaryland1988-1990 ScientificAdvisoryBoardofInterconPharmaInc.1984-1986 BoardofDirectors,AmericanDermatologicSocietyforAllergyand

Immunology

C. BOARD OF DIRECTORS 2004 WelichemBiotechInc.2002 AtlanticDermatologicSocietyConference1997-1998 President,CanadianDermatologyAssociation1992-1995 CanadianSocietyforInvestigativeDermatology(PastPresident)1991-1993 CanadianSocietyforDermatologicSurgery1989-1995 MedicalDirector,OntarioOutwardBound1988-1991 BoardofDirectors,RegionalMedicalAssociatesofHamilton,

Ontario1994-1996 BoardofDirectors,StefInternationalCorporation


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D. EDITORIAL BOARDS • JournalofCutaneousMedicineandSurgery(Editor-in-Chief)• JournalofInvestigativeDermatology• LymphokineResearch• JournalofAmericanAcademyofDermatology(PastAssistantEditor)• RegionalImmunology(PastEditorialBoard)• CanadianJournalofDermatology(PastAssociateEditor)• AmericanJournalofContactDermatitis(EditorialBoardMember)• InternationalJournalofImmunopathologyandPharmacology• JapaneseDermatologicalAssociation• CurrentProblemsinDermatology

E. INSTITUATIONAL ADMINISTRATIVE APPOINTMENTS 2003-Present LeadershipDevelopmentProgram,JohnsHopkinsMedicine2002-Present ClinicalResearchBuildingIIPlanningCouncil,JohnsHopkins

Medicine2002-Present AdvisoryBoardoftheMedicalFaculty,JohnsHopkinsMedicine2002-Present JohnsHopkinsMedicalBoard,JohnsHopkinsMedicine2002-Present ClinicalDirectorsCommittee,JohnsHopkinsMedicine2002-2004 ContractingCommittee,JohnsHopkinsMedicine1997-2000 Chair,DecanalPromotionsCommittee,UniversityofToronto1994-1997 DecanalPromotionsCommittee,UniversityofToronto1994-2000 DepartmentofMedicineResearchCommittee,SunnybrookHealth

ScienceCentre1993-1996 Director,GeneralResearchProgram,SunnybrookHealthScience

Centre1991-1993 SunnybrookHealthScienceCentre,DepartmentofMedicine

PromotionandTenureCommittee1991-1998 Chairman,OntarioCollegeofPhysicians-IndependentHealth

Facilities,DermatologyTaskForce1989-1990 CommitteeforScientificDevelopment,SubcommitteeRegarding

ResearchSpace,McMasterUniversity1989-1990 ResearchEthicsandProjectReviewBoard,(EthicsCommittee),

McMasterUniversityFacultyofHealthSciences1989-1990 OntarioAIDSAdvisoryCommittee(SubcommitteeonCo-ordination

ofServices),OntarioMinistryofHealth1988-1990 CommitteeforEquipmentinClinicalSettings1988-1991 RegionalMedicalAssociatesofHamilton,McMasterUniversity1987-1992 CounciloftheFacultyofHealthSciencesMcMasterUniversity,

FacultyofHealthScience1987-1990 AIDSConsultantGroup-HamiltonAcademyofMedicine1987-1990 SubcommitteeonProvisionofClinicalService(AIDS),H-WRegional

HealthCouncil


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1987-1990 ChairmanoftheAIDSAcademicandResearchSubcommitteeHamiltonWentworth(H-W)RegionalHealthCouncil

1987-1990 SenateAdHocSearchCommitteeforChairmanofDepartmentofMedicine-McMasterUniversity

1987-1990 PromotionsandTenureCommittee,McMasterUniversity1986-1990 AIDSSteeringCommittee,H-WRegionalHealthCouncil1982-1990 MolecularVirologyandImmunologyProgram,McMasterUniversity1982-1990 MedicalStaffComputerCommittee,McMasterUniversity

F. PROFESSIONAL SOCIETIES 2001-2005 MarylandDermatologicSociety1997-2002 CommitteeonFinances,SocietyforInvestigativeDermatology1995 Chair,EducationCommittee,AmericanDermatologyAssociation1992 EducationCommittee,AmericanDermatologicalAssociation.1992-2000 CanadianSocietyforInvestigativeDermatology(Founding

President)1991 AmericanCollegeofPhysicians1988 AmericanDermatologicAssociation1982 FederationofAmericanSocietiesforExperimentalBiologies1982 CanadianDermatologyAssociation1982 AmericanFederationforClinicalResearch1982 AmericanAcademyofDermatology1982 AmericanAssociationofImmunologists1982 CanadianSocietyforClinicalInvestigation1982 CanadianSocietyofImmunologists1980 RoyalCollegeofPhysiciansandSurgeonsofCanada1978 DermatologyFoundation1977 SocietyofInvestigativeDermatology1976 AmericanCollegeofPhysicians1974 CanadianMedicalAssociation1974 OntarioMedicalAssociation

G. RECOGNITION, AWARDS AND HONORS 2005 AmericanMelanomaFoundation,PhysicianRecognitionAward2002 Chair,ScientificSessions;AtlanticDermatologicSociety2002 IsraelZeligmanMemorialLecturer;Baltimore,Maryland2001 Member,JohnsHopkinsAdvisoryBoardoftheMedicalFaculty1997-1998 President,CanadianDermatologyAssociation1992-1995 President,CanadianSocietyforInvestigativeDermatology1994 SunnybrookDepartmentofMedicineResearchAward1992 ElectedtoAmericanSocietyforClinicalInvestigation(ASCI)1991 FACP-FellowofTheAmericanCollegeofPhysicians1988 Member,AmericanDermatologicalAssociation


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1987 NormanWrongLecturer-9thPostGraduateMeeting,Toronto,Ontario

1986 MemberofMcMasterAlumniGallery1984 YoungLeadershipAwardoftheAmericanDermatological

Association1982 ProvinceofOntarioCareerScientistAward1979 MedicalResearchCouncilFellowship1979 HenryW.StelwagonAward1976 Associate,AmericanCollegeofPhysicians1971 OntarioGraduateFellowship1971 YorkUniversitySenateScholarship1971 NationalResearchCouncilScholarship1970 YorkUniversityFacultyofArtsScholarship1970 AtkinsonFoundationBursary

H. MANUSCRIPT REVIEWS • JournalofImmunology• JournalofClinicalInvestigation• ProceedingsofNationalAcademyofScience(U.S.A.)• JournalofInvestigativeDermatology• ArchivesofDermatology• LymphokineResearch• JournaloftheAmericanAcademyofDermatology• JournalofLeukocyteBiology• BritishJournalofDermatology

I. EXTERNAL GRANT REVIEWS • BritishColumbiaHealthFoundation• DermatologyFoundation• MedicalResearchCouncilofCanada• NationalInstitutesofHealth• OntarioMinistryofHealth• CanadianHeartFoundation• CanadianArthritisAssociation• NationalCancerInstitute• Physicians'ServicesIncorporated

J. CONSULTING • 3MPharmaceuticals(2001-present)ScientificAdvisor• Biogen-Idec(2001-present)ScientificAdvisor• Amgen(2001-present)ScientificAdvisor• Centocor(2001-present)ScientificAdvisor• Genentech(2001-present)ScientificAdvisor


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II. RESEARCH ACTIVITIES

A. INVENTIONS, PATENTS AND COPYRIGHTS 1. Ultrasoundtechniqueforassessinginflammationandcontactdermatitis.Disclosure

Document#417112,1997.ChristopherDA,ShivjiGM,FosterFS,andSauderDN.2. Biodegradablematerialforwounddressings.#08/847,845,1997.WoodhouseKA,

SauderDN,SkarjaGA.TreatmentofInflammatoryandAllergicDisorders.SauderDN,etal.AppliedforApril1999.

3. TreatmentofHypersensitivityReactionDisorders.#2269364,1999.SauderDN,

MandelA,BoltonAD,HironsRG.4. ContactHypersensivity.#29312-0094USPatent.SauderDN.5. TreatmentofIL-10Deficiences.#29312-0136InternationalPatent.VasogenIreland

Limited,SauderDN.AppliedforMay2001.6. InflammatoryCytokineSecretionInhibition.#29312-0150InternationalPatent.

VasogenIrelandLimited,Bolton,AN,MandelA,SauderDN.AppliedforDecember2001.

7. TransformingGrowthFactorRegulation.#29312-0148InternationalPatent.

VasogenIrelandLimited.BoltonAE,MandelA,SauderDN.AppliedforDecember2001

B. PUBLICATIONS Peer-Reviewed Articles

1. SauderDN,SauderMB.Molecularmechanismsinpsoriasis:historicalperspectiveandcurrentpathogenesis.ExpertReviewofDermatology,February2013,Vol.8,No.1,Pages1-3.

2. NekoroskiT,PaladiniRD,SauderDN,FrostGI,KellerGA.ARecombinantHumanHyaluronidaseSustainedReleaseGelfortheTreatmentofPost-SurgicalEdema.InternationalJournalofDermatology(inpress)

3. ShahA,PeloroTM,SauderDN.Squamouscellcarcinomamanifestingascutaneouscysticlesions.Cutis.2012Jan;89(1):45-7.


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4. SauderDN.Light-emittingdiodes:theirroleinskinrejuvenation.IntJDermatol.2010Jan;49(1):12-6

5. StetskoD,SauderDN.IL-12andIL-23inhealthanddisease.ExpertRevClinImmunol.2008May;4(3):301-3.

6. KowalskiJ,MariannaZahurakM,BlackfordA,FengC,MamelakAJ,SauderDN.NestedNonparametric,CorrelativeAnalysiofMicroarraysforHetergenousPhenotypecharacterization.StiatisticsInMedicine.2007Feb28;26(5):1090-101.

7. RabeJH,MamelakAJ,McElgunnPJ,MorisonWL,SauderDN.Photoaging:mechanismsandrepair.JAmAcadDermatol2005JAmAcadDermatol2006;55:1-19.

8. SauderDN,HowellB,SolishN,LuC,WatanabeH,MamelakA,WangB,FreedI.MicroarrayProfilesofHumanBasalCellCarcinoma:InsightsintoTumorGrowthandBehavior.JDermatolSci2005Jul;39(1):39-51

9. SauderDN,TanSR,McDermottMR,CastilloCJ.PemphigusVulgarisInducedbyElectricalInjury.Cutis2005. Mar;77(3):161-5.

10. MamelakA,KowalskiJ,MurphyK,YadaraN,ZahurakM,KoubaD,HowellB,TzuJ,CumminsD,LiégeoisN,BergK,SauderDN.DownregulationofNDUFA1andotheroxidativephosphorylation-relatedgenesisaconsistentfeatureofbasalcellcarcinoma.ExpDermatol.2005May;14(5):336-48.

11. WatanabeH,MamelakAJ,WeissE,WangB,FreedI,BriceAK,WachtmanL,GabrielsonKL,YokotaN,HicklinDJ,KerbelRS,HaasM,SauderDN.Anti-vascularendothelialgrowthfactorreceptor-2antibodyacceleratesrenaldiseaseintheNZB/WF1murinesystemiclupuserythematosusmodel.ClinCancerRes.2005Jan1;11(1):407-9.

12. WatanabeH,MamelakAJ,WangB,HowellBG,FreedI,EscheC,NakayamaM,NagasakiG,HicklinDJ,KerbelRS,SauderDN.Anti-vascularendothelialgrowthfactorreceptor-2(Flk-1/KDR)antibodysuppresscontacthypersensitivity.ExpDermatol2004Nov;13(11):671-81.

13. InghamKC,BrewS,VazD,SauderDN,McGavinMJInteractionofStaphylococcusaureusfibronectin-bindingproteinwithfibronectin:affinity,stoichiometry,andmodularrequirements.JBiolChem.2004Oct8;279(41):42945-53.

14. WeissE,MamelakAJ,LaMorgiaS,WangB,FelicianiC,TulliA,SauderDN.Theroleofinterleukin10inthepathogenesisandpotentialtreatmentofskindiseases.JAmAcadDermatol.2004May;50(5):657-75;quiz676-8.


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15. HowellBG,WangB,FreedI,MamelakAJ,WatanabeH,SauderDN.MicroarrayanalysisofUVB-regulatedgenesinkeratinocytes:downregulationofangiogenesisinhibitorthrombospondin-1.JDermatolSci.2004May;34(3):185-94.

16. YooSS,MimouniD,NikolskaiaOV,KoubaDJ,SauderDN,NousariCH.Clinicopathologicfeaturesofulcerative-atrophicsarcoidosis.InternationalJournalofDermatology2004;43(2):108-112.

17. SauderDN,SmithMH,Senta-McMillianT,SoriaI,MengTC.Randomized,single-blind,placebo-controlledstudyoftopicalapplicationoftheimmuneresponsemodulatorresiquimodinhealthyadults.AntimicrobialAgentsandChemotherapy2003;47(12):3846-3852.

18. DupontE,WangB,MamelakAJ,HowellBG,ShivjiG,ZhuangLetal.ModulationofthecontacthypersensitivityresponsebyAE--941(Neovastat),anovelantiangiogenicagent.JournalofCutaneousMedicineandSurgery2003;7(3):208-216.

19. SauderDN,SkinnerRB,FoxTL,OwensML.Topicalimiquimod5%creamasaneffectivetreatmentforexternalgenitalandperianalwartsindifferentpatientpopulations.SexuallyTransmittedDiseases2003;30(2):124-128.

20. KawaraS,MydlarskiR,MamelakAJ,FreedI,WangB,WatanabeHetal.Low-doseultravioletBraysalterthemRNAexpressionofthecircadianclockgenesinculturedhumankeratinocytes.JournalofInvestigativeDermatology2002;119(6):1220-1223.

21. SauderDN,DeKovenJ,ChampagneP,CroteauD,DupontE.Neovastat(AE-941),aninhibitorofangiogenesis:RandomizedphaseI/IIclinicaltrialresultsinpatientswithplaquepsoriasis.JournaloftheAmericanAcademyofDermatology2002;47(4):535-541.

22. WangB,WatanabeH,ShinT,HowellBG,FreedI,MamelakAJetal.MarineepidermalLangerhanscellsexpressB7-DC,anewB7familymember,aftermaturation.JournalofInvestigativeDermatology2002;119(1):312.

23. WatanabeH,UngerM,TuvelB,WangBH,SauderDN.Contacthypersensitivity:ThemechanismofimmuneresponsesandTcellbalance.JournalofInterferonandCytokineResearch2002;22(4):407-412.

24. HuescaM,PeraltaR,SauderDN,SimorAE,McGavinMJ.AdhesionandvirulencepropertiesofepidemicCanadianmethicillin-resistantStaphylococcusaureusstrain1:Identificationofnoveladhesionfunctionsassociatedwithplasmin-sensitivesurfaceprotein.JournalofInfectiousDiseases2002;185(9):1285-1296.


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25. SuzukiH,KalairW,ShivjiGM,WangBH,TotoP,AmerioPetal.Impairedultraviolet-B-inducedcytokineinductioninxerodermapigmentosumfibroblasts.JournalofInvestigativeDermatology2001;117(5):1151-1155.

26. AmerioP,VerdoliniR,ProiettoG,FelicianiC,TotoP,ShivjiGetal.RoleofTh2cytokines,RANTESandeotaxininAIDS-associatedeosinophilicfolliculitis.ActaDermato-Venereologica2001;81(2):92-95.

27. AmerioP,TotoP,FelicianiC,SuzukiH,ShivjiG,WangBetal.Rethinkingtheroleoftumournecrosisfactor-alphainultraviolet(UV)B-inducedimmunosuppression:alteredimmuneresponseinUV-irradiatedTNFR1R2gene-targetedmutantmice.BritishJournalofDermatology2001;144(5):952-957.

28. Zak-PrelichM,NorvalM,VennerTJ,BissetY,WalkerC,RaffertyTSetal.cis-Urocanicaciddoesnotinducetheexpressionofimmunosuppressivecytokinesinmurinekeratinocytes.PhotochemistryandPhotobiology2001;73(3):238-244.

29. WangBH,FujisawaH,ZhuangLH,FreedI,HowellBG,ShahidSetal.CD4(+)Th1andCD8(+)type1cytotoxicTcellsbothplayacrucialroleinthefulldevelopmentofcontacthypersensitivity.JournalofImmunology2000;165(12):6783-6790.

30. TurnerMS,SuttonD,SauderDN.Theuseofplasmapheresisandimmunosuppressioninthetreatmentofpemphigusvulgaris.JournaloftheAmericanAcademyofDermatology2000;43(6):1058-1064.

31. ZhuangLH,WangBH,SauderDN.Molecularmechanismofultraviolet-inducedkeratinocyteapoptosis.JournalofInterferonandCytokineResearch2000;20(5):445-454.

32. TavadiaSMB,MydlarskiPR,ReisMD,MittmannN,PinkertonPH,ShearNetal.Screeningforazathioprinetoxicity:Apharmacoeconomicanalysisbasedonatargetcase.JournaloftheAmericanAcademyofDermatology2000;42(4):628-632.

33. HuescaM,SunQ,PeraltaR,ShivjiGM,SauderDN,McGavinMJ.SyntheticpeptideimmunogenselicitpolyclonalandmonoclonalantibodiesspecificforlinearepitopesintheDmotifsofStaphylococcusaureusfibronectin-bindingprotein,whicharecomposedofaminoacidsthatareessentialforfibronectinbinding.InfectionandImmunity2000;68(3):1156-1163.

34. FelicianiC,TotoP,AmerioP,PourSM,CoscioneG,AmerioPetal.InvitroandInvivoexpressionofinterleukin-1alphaandtumornecrosisfactor-alphamRNAinpemphigusvulgaris:Interleukin-1alphaandtumornecrosisfactor-alphaareinvolvedinacantholysis.JournalofInvestigativeDermatology2000;114(1):71-77.


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35. SuzukiH,WangBH,ShivjiGM,TotoP,AmerioP,TomaiMAetal.Imiquimod,atopicalimmuneresponsemodifier,inducesmigrationofLangerhanscells.JournalofInvestigativeDermatology2000;114(1):135-141.

36. TotoP,FelicianiC,AmerioP,SuzukiH,WangBH,ShivjiGMetal.ImmunemodulationinPemphigusvulgaris:RoleofCD28andIL-10.JournalofImmunology2000;164(1):522-529.

37. WangBH,AmerioP,SauderDN.RoleofcytokinesinepidermalLangerhanscellmigration.JournalofLeukocyteBiology1999;66(1):33-39.

38. ZhuangLH,WangBH,ShinderGA,ShivjiGM,MakTW,SauderDN.TNFreceptorp55playsapivotalroleinmurinekeratinocyteapoptosisinducedbyultravioletBirradiation.JournalofImmunology1999;162(3):1440-1447.

39. WangB,ZhuangLH,FujisawaH,ShinderGA,FelicianiC,ShivjiGMetal.EnhancedepidermalLangerhanscellmigrationinIL-10knockoutmice.JournalofImmunology1999;162(1):277-283.

40. GuptaAK,FilonenkoN,SalanskyN,SauderDN.Theuseoflowenergyphotontherapy(LEPT)invenouslegulcers:Adouble-blind,placebo-controlledstudy.DermatologicSurgery1998;24(12):1383-1386.

41. WeichertG,SauderDN.Efficacyoftacrolimus(FK506)inidiopathictreatment-resistantpyodermagangrenosum.JournaloftheAmericanAcademyofDermatology1998;39(4):648-650.

42. WangBH,FujisawaH,ZhuangLH,KondoS,ShivjiGM,KimCSetal.DepressedLangerhanscellmigrationandreducedcontacthypersensitivityresponseinmicelackingTNFreceptorp75.JournalofImmunology1997;159(12):6148-6155.

43. GuptaAK,KovacsMJ,SauderDN.Heparin-inducedthrombocytopenia.AnnalsofPharmacotherapy1998;32(1):55-59.

44. FujisawaH,KondoS,WangBH,ShivjiGM,SauderDN.TheexpressionandmodulationofIFN-alphaandIFN-betainhumankeratinocytes.JournalofInterferonandCytokineResearch1997;17(12):721-725.

45. WangBH,SauderDN.''Normal''developmentofVgamma3dendriticepidermalTcellsinCD45-deficientmice?Reply.JournalofInvestigativeDermatology1997;109(2):250-251.

46. LeeHST,KoosheshF,SauderDN,KondoS.ModulationofTGF-beta1productionfromhumankeratinocytesbyUVB.ExperimentalDermatology1997;6(2):105-110.


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47. SauderDN,MillerR,GrattonD,DanbyW,GriffithsC,PhillipsSB.Thetreatmentofrosacea:Thesafetyandefficacyofsodiumsulfacetamide10%andsulfur5%lotion(Novacet)isdemonstratedinadouble-blindstudy.JournalofDermatologicalTreatment1997;8(2):79-85.

48. GuptaAK,TelferI,FilonenkoN,SalanskyN,SauderDN.Theuseoflow-energyphotontherapyinthetreatmentoflegulcers-apreliminarystudy.JournalofDermatologicalTreatment1997;8(2):103-108.

49. KondoS,SauderDN.Tumornecrosisfactor(TNF)receptortype1(p55)isamainmediatorforTNF-alpha-inducedskininflammation.EuropeanJournalofImmunology1997;27(7):1713-1718.

50. FujisawaH,WangBH,SauderDN,KondoS.Effectsofinterferonsontheproductionofinterleukin-6andinterleukin-8inhumankeratinocytes.JournalofInterferonandCytokineResearch1997;17(6):347-353.

51. FujisawaH,WangBH,KondoS,ShivjiGM,SauderDN.CostimulationwithultravioletBandinterleukin-1alphadramaticallyincreasetumornecrosisfactor-alphaproductioninhumandermalfibroblasts.JournalofInterferonandCytokineResearch1997;17(5):307-313.

52. KondoS,KoosheshF,SauderDN.Penetrationofkeratinocyte-derivedcytokinesintobasementmembrane.JournalofCellularPhysiology1997;171(2):190-195.

53. KondoS,SauderDN.RoleofCD4+TcellsandoftheCD4moleculeincontactsensitivity-Reply.JournalofInvestigativeDermatology1997;108(5):811-812.

54. GuptaAK,ScherRK,DeDonckerP,SauderDN,ShearNH.Onychomycosis-Newtherapiesforanolddisease.WesternJournalofMedicine1996;165(6):349-351.

55. WangBH,FujisawaH,KondoS,ShivjiGG,SauderDN.CD45moleculeingammadeltaTcellgeneration:DisruptionofCD45exon6doesnotaffectVgamma3dendriticepidermalT-celldevelopment.JournalofInvestigativeDermatology1997;108(1):49-52.

56. FelicianiC,GuptaAK,SauderDN.Keratinocytesandcytokine/growthfactors.CriticalReviewsinOralBiology&Medicine1996;7(4):300-318.

57. KondoS,KoosheshF,WangB,FujisawaH,SauderDN.ContributionoftheCD28moleculetoallergicandirritant-inducedskinreactionsinCD28-/-mice.JournalofImmunology1996;157(11):4822-4829.

58. FujisawaH,KondoS,WangB,ShivjiGM,SauderDN.TheroleofCD4moleculesintheinductionphaseofcontacthypersensitivitycytokineprofilesintheskinandlymphnodes.Immunology1996;89(2):250-255.


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59. TurnbullDH,RamsayJA,ShivjiGS,BloomfieldTS,FromL,SauderDNetal.Ultrasoundbackscattermicroscopeanalysisofmousemelanomaprogression.UltrasoundinMedicineandBiology1996;22(7):845-853.

60. FujisawaH,ShivjiGM,KondoS,WangBH,TomaiMA,MillerRLetal.Effectofanoveltopicalimmunomodulator,S-28463,onkeratinocytecytokinegeneexpressionandproduction.JournalofInterferonandCytokineResearch1996;16(7):555-559.

61. GuptaAK,TurnbullDH,HarasiewiczKA,ShumDT,WatteelGN,FosterSetal.Theuseofhigh-frequencyultrasoundasamethodofassessingtheseverityofaplaqueofpsoriasis.ArchivesofDermatology1996;132(6):658-662.

62. WangB,KondoS,ShivjiGM,FujisawaH,MakTW,SauderDN.TumournecrosisfactorreceptorII(p75)signallingisrequiredforthemigrationofLangerhans'cells.Immunology1996;88(2):284-288.

63. PagliaD,KondoS,NgKME,SauderDN,McKenzieRC.Leukaemiainhibitoryfactorisexpressedbynormalhumankeratinocytesinvitroandinvivo.BritishJournalofDermatology1996;134(5):817-823.

64. KondoS,BeissertS,WangBH,FujisawaH,KoosheshF,StratigosAetal.HyporesponsivenessincontacthypersensitivityandirritantcontactdermatitisinCD4genetargetedmouse.JournalofInvestigativeDermatology1996;106(5):993-1000.

65. McKenzieRC,PagliaD,KondoS,SauderDN.Anovelendogenousmediatorofcutaneousinflammation:Leukemiainhibitoryfactor.ActaDermato-Venereologica1996;76(2):111-114.

66. McKenzieRC,OranA,DinarelloCA,SauderDN.Interleukin-1receptorantagonistinhibitssubcutaneousB16melanomagrowthinvivo.AnticancerResearch1996;16(1):437-441.

67. KondoS,SauderDN,McKenzieRC,FujisawaH,ShivjiGM,ElGhorrAetal.Theroleofcis-urocanicacidinUVB-inducedsuppressionofcontacthypersensitivity.ImmunologyLetters1995;48(3):181-186.

68. GuptaAK,TurnbullDH,FosterFS,HarasiewiczKA,ShumDT,PrussickRetal.Highfrequency40-MHzultrasound-Apossiblenoninvasivemethodfortheassessmentoftheboundaryofbasalcellcarcinomas.DermatologicSurgery1996;22(2):131-136.

69. OdaY,TimpeL,McKenzieRC,SauderDN,LargmanC,MauroT.AlternativelysplicedisoformsofcGMP-gatedcationchannelfromhumankeratinocytes.JournalofInvestigativeMedicine1996;44(1):A185.


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70. KondoS,WangBH,FujisawaH,ShivjiGM,EchtenacherB,MakTWetal.EffectofGene-TargetedMutationinTnfReceptor(P55)onContactHypersensitivityandUltravioletB-InducedImmunosuppression.JournalofImmunology1995;155(8):3801-3805.

71. KondoS,PastoreS,FujisawaH,ShivjiGM,McKenzieRC,DinarelloCAetal.Interleukin-1ReceptorAntagonistSuppressesContactHypersensitivity.JournalofInvestigativeDermatology1995;105(3):334-338.

72. SempleJL,GuptaAK,FromL,HarasiewiczKA,SauderDN,FosterFSetal.DoesHigh-Frequency(40-60Mhz)UltrasoundImagingPlayARoleintheClinicalManagementofCutaneousMelanoma.AnnalsofPlasticSurgery1995;34(6):599-605.

73. KonoT,KondoS,VennerTJ,SauderDN,McKenzieRC.InhibitionofCytokineGene-ExpressioninMouseSkinbySubcutaneousInjectionofCyclosporine.SkinPharmacology1995;8(3):149-155.

74. PagliaD,OranA,LuC,KerbelRS,SauderDN,McKenzieRC.ExpressionofLeukemiaInhibitoryFactorandInterleukin-11byHuman-MelanomaCell-Lines-Lif,Il-6,andIl-11AreNotCoregulated.JournalofInterferonandCytokineResearch1995;15(5):455-460.

75. ChenJD,LapiereJC,SauderDN,PeaveyC,WoodleyDT.Interleukin-1-AlphaStimulatesKeratinocyteMigrationThroughAnEpidermalGrowth-FactorTransformingGrowthFactor-Alpha-IndependentPathway.JournalofInvestigativeDermatology1995;104(5):729-733.

76. KondoS,WangB,FujisawaH,ShivjiGM,EchtenacherB,MakTMetal.EffectsofGene-TargetedMutationinTnf-R(P55)onContactHypersensitivityandUvInducedImmunosuppression.JournalofInvestigativeDermatology1995;104(4):569.

77. PastoreS,ShivjiGM,KondoS,KonoT,McKenzieRC,SegalLetal.EffectsofContactSensitizersNeomycinSulfate,Benzocaineand2,4-Dinitrobenzene1-Sulfonate,Sodium-SaltonViability,MembraneIntegrityandIl-1-AlphaMessenger-RnaExpressionofCulturedNormalHumanKeratinocytes.FoodandChemicalToxicology1995;33(1):57-68.

78. DickD,NgKME,SauderDN,ChuI.In-VitroandIn-VivoPercutaneous-AbsorptionofC-14ChloroforminHumans.Human&ExperimentalToxicology1995;14(3):260-265.

79. KondoS,CiarlettaA,TurnerKJ,SauderDN,McKenzieRC.FailuretoDetectInterleukin(Il)-3Messenger-RnaOrProteininHumanKeratinocytes-AntibodiestoGranulocyteMacrophage-Colony-StimulatingFactorOrIl-6(ButNotIl-3)NeutralizeIl-3Bioactivity.JournalofInvestigativeDermatology1995;104(3):335-339.


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80. TurnbullDH,StarkoskiBG,HarasiewiczKA,SempleJL,FromL,GuptaAKetal.40-100-MhzB-ScanUltrasoundBackscatterMicroscopeforSkinImaging.UltrasoundinMedicineandBiology1995;21(1):79-88.

81. KondoS,McKenzieRC,SauderDN.Interleukin-10InhibitstheElicitationPhaseofAllergicContactHypersensitivity.JournalofInvestigativeDermatology1994;103(6):811-814.

82. GuptaAK,ShearNH,SauderDN.EfficacyofHumanIntravenousImmuneGlobulininPyoderma-Gangrenosum.JournaloftheAmericanAcademyofDermatology1995;32(1):140-142.

83. KondoS,PastoreS,ShivjiGM,McKenzieRC,SauderDN.CharacterizationofEpidermalCytokineProfilesinSensitizationandElicitationPhasesofAllergicContact-DermatitisAsWellAsIrritantContact-DermatitisinMouseSkin.LymphokineandCytokineResearch1994;13(6):367-375.

84. McKenzieRC,GalleyKA,VennerTJ,KondoS,SauderDN.SpecificBindingandLackofGrowth-PromotingActivityofSubstance-PinCulturedHumanKeratinocytes.JournalofInvestigativeDermatology1994;103(4):606.

85. KondoS,KonoT,BrownWR,PastoreS,McKenzieRC,SauderDN.LymphocyteFunction-AssociatedAntigen-1IsRequiredforMaximumElicitationofAllergicContact-Dermatitis.BritishJournalofDermatology1994;131(3):354-359.

86. McKenzieRC,ParkES,BrownWR,ShivjiGS,SauderDN.EffectofUltraviolet-InducibleCytokinesonMelanomaGrowthIn-Vivo-StimulationofMelanomaGrowthbyInterleukin-1andInterleukin-6.PhotodermatologyPhotoimmunology&Photomedicine1994;10(2):74-79.

87. ShivjiGM,SegalL,McKenzieRC,SauderDN.CutaneousToxicityofSurfactantsinNormalHumanKeratinocytesAssessedbyCytotoxicity,Arachidonic-AcidRelease,andRegulationofInterleukin-1-AlphaMessenger-Rna.ToxicologyMethods1994;4(3):193-203.

88. McKenzieRC,VennerTJ,SauderDN,FarkashimsleyH.AugmentationofInterleukin-6(Il-6)ExpressioninSquamousCarcinoma-CellsandNormalHumanKeratinocytesTreatedwithRecombinantAntineoplasticProtein(Acp).AnticancerResearch1994;14(3A):1165-1168.

89. WallaceVA,KondoS,KonoT,XingZ,TimmsE,FurlongerCetal.ARoleforCd4+T-CellsinthePathogenesisofSkinFibrosisinTight-SkinMice.EuropeanJournalofImmunology1994;24(6):1463-1466.


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90. KonoT,KondoS,PastoreS,ShivjiGM,TomaiMA,McKenzieRCetal.EffectsofANovelTopicalImmunomodulator,Imiquimod,onKeratinocyteCytokineGene-Expression.LymphokineandCytokineResearch1994;13(2):71-76.

91. SwopeVB,SauderDN,McKenzieRC,SramkoskiRM,KrugKA,BabcockGFetal.SynthesisofInterleukin-1-AlphaandInterleukin-1-BetabyNormalHumanMelanocytes.JournalofInvestigativeDermatology1994;102(5):749-753.

92. PrussickR,GuptaAK,AssaadDM,HannaWM,SauderDN.Epidermolysis-BullosaAcquisitawithFeaturesofBullousLupus-Erythematosus.InternationalJournalofDermatology1994;33(3):192-195.

93. WonYH,SauderDN,McKenzieRC.Cyclosporine-AInhibitsKeratinocyteCytokineGene-Expression.BritishJournalofDermatology1994;130(3):312-319.

94. WismerJM,McKenzieRC,SauderDN.Interleukin-8ImmunoreactivityinEpidermisofCutaneousT-CellLymphomaPatients.LymphokineandCytokineResearch1994;13(1):21-27.

95. KondoS,KonoT,SauderDN,McKenzieRC.Il-8Gene-ExpressionandProductioninHumanKeratinocytesandTheirModulationbyUvb.JournalofInvestigativeDermatology1993;101(5):690-694.

96. GuptaAK,ShearNH,LesterRS,BaxterML,SauderDN.BetamethasoneDipropionatePolyacrylicFilm-FormingLotionintheTreatmentofHandDermatitis.InternationalJournalofDermatology1993;32(11):828-829.

97. ContiP,FelicianiC,BarbacaneRC,PanaraMR,RealeM,PlacidoFCetal.InhibitionofInterleukin-1-BetaMessenger-RnaExpressionandInterleukin-1-AlphaandInterleukin-1-BetaSecretionbyASpecificHumanRecombinantInterleukin-1ReceptorAntagonistinHumanPeripheral-BloodMononuclear-Cells.Immunology1992;77(2):245-250.

98. JonesG,McleanJ,RosenthalD,RobertsJ,SauderDN.CombinedTreatmentwithOralEtretinateandElectron-BeamTherapyinPatientswithCutaneousT-CellLymphoma(Mycosis-FungoidesandSezary-Syndrome).JournaloftheAmericanAcademyofDermatology1992;26(6):960-967.

99. ArsenaultTV,SauderDN,HarleyCB,McKenzieRC.IdentificationandCharacterizationofAPartialCdnaExpressingInterleukin-1-LikeActivityinKeratinocytes.MolecularImmunology1992;29(3):431-438.

100. PrussickR,BrainMC,WalkerIR,SauderDN.Polymyositis-AManifestationofChronicGraft-Versus-HostDisease.JournaloftheAmericanAcademyofDermatology1991;25(3):560-562.


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101. GalloRL,StaszewskiR,SauderDN,KniselyTL,GransteinRD.RegulationofGm-CsfandIl-3ProductionfromtheMurineKeratinocyteCell-LinePam-212FollowingExposuretoUltraviolet-Radiation.JournalofInvestigativeDermatology1991;97(2):203-209.

102. NozakiS,AbramsJS,PearceMK,SauderDN.AugmentationofGranulocyteMacrophageColony-StimulatingFactorExpressionbyUltraviolet-IrradiationIsMediatedbyInterleukin-1inPam-212Keratinocytes.JournalofInvestigativeDermatology1991;97(1):10-14.

103. PatelA,PrussickR,BuchananWW,SauderDN.SerumSicknessLikeIllnessandLeukocytoclasticVasculitisAfterIntravenousStreptokinase.JournaloftheAmericanAcademyofDermatology1991;24(4):652-653.

104. KatzAM,RosenthalD,SauderDN.Cell-AdhesionMolecules-Structure,Function,andImplicationinAVarietyofCutaneousandOtherPathologicalConditions.InternationalJournalofDermatology1991;30(3):153-160.

105. KatzAM,RosenthalD,JakubovicHR,PaiRKM,QuinonezGE,SauderDN.LangerhansCellHistiocytosisinMonozygoticTwins.JournaloftheAmericanAcademyofDermatology1991;24(1):32-37.

106. SauderDN,KilianPL,MclaneJA,QuickTW,JakubovicH,DavisSCetal.Interleukin-1EnhancesEpidermalWound-Healing.LymphokineResearch1990;9(4):465-473.

107. McKenzieRC,ArsenaultTV,SauderDN,HarleyCB.ExpressionofInterleukin-1-BetainAHumanKeratinocyteCell-Line.LymphokineResearch1990;9(3):391-403.

108. CooperKD,HammerbergC,BaadsgaardO,ElderJT,ChanLS,SauderDNetal.Il-1ActivityIsReducedinPsoriaticSkin-DecreasedIl-1-AlphaandIncreasedNonfunctionalIl-1-Beta.JournalofImmunology1990;144(12):4593-4603.

109. SauderDN,ArsenaultT,McKenzieRC,StetskoDK,HarleyCB.BiologyandMolecular-BiologyofEpidermalCell-DerivedThymocyteActivatingFactor.AnnalsoftheNewYorkAcademyofSciences1988;548:241-252.

110. PaganelliparkerK,SauderDN,KilianPL.PresenceofInterleukin-1ReceptorsonKeratinocytes.AnnalsoftheNewYorkAcademyofSciences1988;548:346-347.

111. GalloRL,SauderDN,KniselyTL,GransteinRD.ModulationofGm-CsfandIl-3ProductionbyAMurineKeratinocyteCell-LineFollowingUltraviolet-RadiationExposure.ClinicalResearch1990;38(2):A645.

112. TronVA,CoughlinMD,JangDE,StaniszJ,SauderDN.ExpressionandModulationofNerveGrowth-FactorinMurineKeratinocytes(Pam-212).JournalofClinicalInvestigation1990;85(4):1085-1089.


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113. LichtenwaldDJ,HannaW,SauderDN,JakubovicHR,RosenthalD.PretibialEpidermolysis-Bullosa-ReportofACase.JournaloftheAmericanAcademyofDermatology1990;22(2):346-350.

114. SauderDN,OrrFW,MaticS,StetskoD,ParkerKP,ChizzoniteRetal.HumanInterleukin-1-AlphaIsChemotacticforNormalHumanKeratinocytes.ImmunologyLetters1989;22(2):123-127.

115. CinaderB,DubiskiS,GreenwoodC,PonnappanU,SauderDN.EconomicCorrection-QuantityandAge-RelatedRateofChange.MechanismsofAgeingandDevelopment1989;48(2):111-116.

116. SwopeVB,AbdelmalekZA,SauderDN,NordlundJJ.ANewRoleforEpidermalCell-DerivedThymocyteActivatingFactor/Il-1AsAnAntagonistforDistinctEpidermal-CellFunction.JournalofImmunology1989;142(6):1943-1949.

117. SauderDN,PonnappanU,CinaderB.EffectofAgeonCutaneousInterleukin-1Expression.ImmunologyLetters1989;20(2):111-114.

118. LauriD,BertomeuMC,OrrFW,BastidaE,SauderDN,BuchananMR.Differential-EffectsofInterleukin-1andFormylmethionylleucylphenylalanineonChemotaxisandHumanEndotheliumAdhesivityforA549Tumor-Cells.LaboratoryInvestigation1989;60(1):161-164.

119. OrrFW,BuchananMR,TronVA,GuyD,LauriD,SauderDN.ChemotacticActivityofEndothelialCell-DerivedInterleukin-1forHuman-TumorCells.CancerResearch1988;48(23):6758-6763.

120. DolovichJ,RuhnoJ,SauderDN,AhlstedtS,HargreaveFE.IsolatedLateCutaneousSkin-TestResponsetoAmpicillin-ADistinctEntity.JournalofAllergyandClinicalImmunology1988;82(4):676-679.

121. NevilleAJ,SauderDN.Whole-BodyHyperthermia(41-42-Degrees-C)InducesInterleukin-1Invivo.LymphokineResearch1988;7(3):201-206.

122. PriceJE,SauderDN,FidlerIJ.TumorigenicityandMetastaticBehaviorinNude-Miceof2HumanSquamous-CellCarcinomaLinesThatDifferinProductionoftheCytokineEtaf/Il-1.JournalofInvestigativeDermatology1988;91(3):258-262.

123. TronVA,HarleyCB,CaussyD,SauderDN.InsituDetectionofInterleukin-1Messenger-RnainHuman-Monocytes.MolecularImmunology1988;25(5):439-445.

124. MertzPM,DavisSC,KilianP,SauderDN.TheEffectofTopicalInterleukin-1ontheEpidermalHealingRateofPartialThicknessWound.ClinicalResearch1988;36(3):A378.


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125. SauderDN,StanulispraegerBM,GilchrestBA.AutocrineGrowth-StimulationofHumanKeratinocytesbyEpidermalCell-DerivedThymocyte-ActivatingFactor-ImplicationsforSkinAging.ArchivesofDermatologicalResearch1988;280(2):71-76.

126. TronVA,RosenthalD,SauderDN.EpidermalInterleukin-1IsIncreasedinCutaneousT-CellLymphoma.JournalofInvestigativeDermatology1988;90(3):378-381.

127. PillaiPS,ReynoldsSD,ScottDW,GauldieJ,SauderDN.RoleofEpidermal-CellThymocyte-ActivatingFactorintheProliferationandDifferentiationofMurineB-Cells.JournalofLeukocyteBiology1987;42(3):222-229.

128. GransteinRD,SauderDN.Whole-BodyExposuretoUltraviolet-RadiationResultsinIncreasedSerumInterleukin-1ActivityinHumans.LymphokineResearch1987;6(3):187-193.

129. ChoiKL,SauderDN.EpidermalLangerhansCell-DensityandContactSensitivityinYoungandAgedBalb/CMice.MechanismsofAgeingandDevelopment1987;39(1):69-79.

130. GauldieJ,SauderDN,McadamKPWJ,DinarelloCA.PurifiedInterleukin-1(Il-1)fromHuman-MonocytesStimulatesAcute-PhaseProtein-SynthesisbyRodentHepatocytesInvitro.Immunology1987;60(2):203-207.

131. KragballeK,MarceloCL,VoorheesJJ,SauderDN.FormationofEpidermal-CellThymocyte-ActivatingFactor(Etaf)fromCulturedHumanKeratinocytesfromNormalandUninvolvedPsoriaticSkin.JournalofInvestigativeDermatology1987;88(1):8-10.

132. SauderDN,SempleJ,TruscottD,GeorgeB,ClowesGHA.StimulationofMuscleProtein-DegradationbyMurineandHumanEpidermalCytokines-RelationshiptoThermal-Injury.JournalofInvestigativeDermatology1986;87(6):711-714.

133. KojA,GauldieJ,SweeneyGD,RegoecziE,SauderDN.ASimpleBioassayforMonocyte-DerivedHepatocyteStimulatingFactor-IncreasedSynthesisofAlpha-2-MacroglobulinandReducedSynthesisofAlbuminbyCulturedRatHepatocytes.JournalofImmunologicalMethods1985;76(2):317-327.

134. KojA,GauldieJ,RegoecziE,SauderDN,SweeneyGD.TheAcute-PhaseResponseofCulturedRatHepatocytes-SystemCharacterizationandtheEffectofHumanCytokines.BiochemicalJournal1984;224(2):505-514.

135. SauderDN.EpidermalCytokines-PropertiesofEpidermal-CellThymocyte-ActivatingFactor(Etaf).LymphokineResearch1984;3(4):145-151.


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136. SauderDN,DinarelloCA,MorhennVB.LangerhansCellProductionofInterleukin-1.JournalofInvestigativeDermatology1984;82(6):605-607.

137. BaumannH,JahreisGP,SauderDN,KojA.HumanKeratinocytesandMonocytesReleaseFactorsWhichRegulatetheSynthesisofMajorAcutePhasePlasma-ProteinsinHepaticCellsfromMan,Rat,andMouse.JournalofBiologicalChemistry1984;259(11):7331-7342.

138. SauderDN,HallRP,WursterCF.DermalMyiasis-thePorcineLipidCure.ArchivesofDermatology1981;117(11):681-682.

139. SauderDN,TamakiK,MoshellAN,FujiwaraH,KatzSI.InductionofTolerancetoTopicallyAppliedTncbUsingTnp-ConjugatedUltravioletLight-IrradiatedEpidermal-Cells.JournalofImmunology1981;127(1):261-265.

140. SauderDN,SteckWD,BailinPB,KrakauerRS.LymphocyteKineticsinPustularPsoriasis.JournaloftheAmericanAcademyofDermatology1981;4(4):458-460.

141. KrakauerRS,SundeenJ,SauderDN,ScherbelA.AbnormalitiesofImmunoregulationinProgressiveSystemic-Sclerosis-EvidenceforExcessHelper-CellFunctionandAlteredB-CellFunction.ArchivesofDermatology1981;117(2):80-82.

142. KrakauerRS,CloughJD,AlexanderT,SundeenJ,SauderDN.Suppressor-CellDefectinSle-RelationshiptoNativeDna-Binding.ClinicalandExperimentalImmunology1980;40(1):72-76.

143. KrakauerRS,CloughJD,SundeenJT,SauderDN,ValenzuelaR,SavageR.SuppressorCellsinCommonVariableHypogammaglobulinemiawithSrbcReceptorsandSurface-Immunoglobulin.ImmunologyLetters1979;1(3):161-164.

144. SauderDN,BailinPL,SundeenJ,KrakauerRS.SuppressorCell-FunctioninPsoriasis.ArchivesofDermatology1980;116(1):51-55.

Peer-Reviewed Clinical Reviews

1. SauderDN,MamelakA.Understandingthenewclinicallandscapeforpsoriasis:acomparativereviewofbiologics.JCutanMedSurg.2004July-Aug;8(4)205-12.

2. SauderDN.Theemergingroleofimmunotherapyinthetreatmentofnon-melanomaskincancers.NatClinPractOncol.2005Jul;2(7):326-7.

3. SauderDN,MofidM.Topicalimmunotherapy:What’sNew.DermatolClin.2005Apr;23(2):245-58.

4. SauderDN.Mechanismofactionandemergingroleofimmuneresponsemodifiertherapyindermatologicconditions.JCutanMedSurg.2004Dec;8Suppl3:3-12.


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5. SauderDN.Imiquimod:modesofaction.BritishJournalofDermatology2003;149:5-8.

6. WangBH,EscheC,MamelakA,FreedI,WatanabeH,SauderDN.Cytokineknockoutsincontacthypersensitivityresearch.Cytokine&GrowthFactorReviews2003;14(5):381-389.

7. GaspariAA,SauderDN.Immunotherapyofbasalcellcarcinoma:Evolvingapproaches.DermatologicSurgery2003;29(10):1027-1034.

8. SauderDN.Thediagnosis,evaluation,andtreatmentofcutaneousT-celllymphoma.CurrentProblemsinDermatology-Us2001;13(6):305-306.

9. WangBH,FelicianiC,FreedI,CaiQC,SauderDN.Insightsintomolecularmechanismsofcontacthypersensitivitygainedfromgeneknockoutstudies.JournalofLeukocyteBiology2001;70(2):185-191.

10. SauderDN.Basicunderstandingofskindisease.CurrentProblemsinDermatology-Us2001;13(3):136.

11. SauderDN,ThibodeauA.Angiogenesisindermatology.CurrentProblemsinDermatology-Us2001;13(3):183-192.

12. SauderDN.Immunomodulatoryandpharmacologicpropertiesofimiquimod.JournaloftheAmericanAcademyofDermatology2000;43(1):S6-S11.

13. SauderDN.Topicaltacrolimus(FK506)iseffectiveinthetreatmentofpyodermagangrenosum-Reply.JournaloftheAmericanAcademyofDermatology2000;42(2):304-305.

14. SauderDN.Molecularmechanisminthecutaneousinflammatoryresponse.JournalofCosmeticScience1999;50(1):77-78.

15. SauderDN.Psoriasistreatment.CurrentProblemsinDermatology-Us1998;10(1):4.

16. GuptaAK,ScherRK,DeDonckerP,SauderDN,ShearNH.Onychomycosis-Adifferentperspective-Response.WesternJournalofMedicine1997;167(1):52-53.

17. KondoS,SauderDN.EpidermalCytokinesinAllergicContact-Dermatitis.JournaloftheAmericanAcademyofDermatology1995;33(5):786-800.

18. GuptaAK,SauderDN,ShearNH.AntifungalAgents-AnOverview.2.JournaloftheAmericanAcademyofDermatology1994;30(6):911-933.

19. GuptaAK,SauderDN,ShearNH.AntifungalAgents-AnOverview.1.JournaloftheAmericanAcademyofDermatology1994;30(5):677-698.


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20. SauderDN,WongD,LaskinC.EpidermalCytokinesinMurineLupus.JournalofInvestigativeDermatology1993;100(1):S42-S46.

21. McKenzieRC,SauderDN.TheRoleofKeratinocyteCytokinesinInflammationandImmunity.JournalofInvestigativeDermatology1990;95(6):S105-S107.

22. SauderDN.TheRoleofEpidermalCytokinesinInflammatorySkinDiseases.JournalofInvestigativeDermatology1990;95(5):S27-S28.

23. McKenzieRC,HarleyCB,MaticS,SauderDN.FetalBovineSerumContainsAnInhibitorofInterleukin-1.JournalofImmunologicalMethods1990;133(1):99-105.

24. SauderDN.Immunodermatology-Preface.DermatologicClinics1990;8(4):R17.

25. McKenzieRC,SauderDN.KeratinocyteCytokinesandGrowth-Factors-FunctionsinSkinImmunityandHomeostasis.DermatologicClinics1990;8(4):649-661.

26. SauderDN.Interleukin-1.ArchivesofDermatology1989;125(5):679-682.

27. SauderDN.EffectofAgeonEpidermalImmuneFunction.DermatologicClinics1986;4(3):447-454.

28. SauderDN.ImmunologyoftheEpidermis-ChangingPerspectives.JournalofInvestigativeDermatology1983;81(3):185-186.

29. StetskoD,SauderDN.IL-12andIL-23inhealthanddisease.ExpertRevClin.Immunol4(3),301-303(2008)

30. SauderDN.IntJDermatol.2010Jan;49(1):12-6.Light-emittingdiodes:theirroleinskinrejuvenation.

Letters and Editorials

1. SauderDN,SauderMB.Molecularmechanismsinpsoriasis:historicalperspectiveandcurrentpathogenesis.ExpertReviewofDermatology,February2013,Vol.8,No.1,Pages1-3.

2. SauderDN.IntroductionBiologics.JCutanMedSurg.2004Dec;8Suppl2:1-2.

3. SauderDN.Foreword:emergingroleoftopicalimmunomodulatorytherapiesindermatology.JCutanMedSurg.2004Dec;8Suppl3:1.

4. SauderDN.Alefacept.JCutanMedSurg2004;1-2.JCMS8(Suppl.2).

5. SauderDN.IntroductiontoBiologics.JournalofCutaneousMedicineandSurgery.2004.Inpress.On-line6Oct2004.www.springerlink.com


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6. SauderDN.CutaneousDrugReactions.CurrentProblemsinDermatology,VolVI,(3)May/June1994.(Editorial).

7. McKenzieRC,GalleyAK,VennerTJ,KondoS,SauderDN.UVBmodulationofIL-1áandIL-1âmRNAlevelsinhumankeratinocytes:Alettertotheeditor.JInvestDermatol.103:604-605,1994.

8. GuptaAK,SauderDN,ShearNH.DrugsofChoice.JAmAcadDermatol.32(6):1060-1061,June1995.

9. GuptaAK,SauderDN,ShearNH.AntifungalAgents(replytoletter).JAmAcadDermatol.32:530-531,1995.

10. KellnerB,SauderDN.Dermatolopathology.Ann.RoyalColl.Phy.SurgCanada.29(3):173-174,1996.

11. KondoS,SauderDN.RoleofCD4+TcellsandoftheCD4moleculeincontactsensitivity(replytoletter).JInvestDermatol.108(5):811-812,1997.

Book Chapters

1. SauderMB,SauderDN.Chapter10:LightEmittingDiodes(LEDs).SynopsisofAestheticDermatologyandCosmeticSurgery(NovaBiomedical).April30,2013

2. SauderDN,WangB,HowellBG,MamelakAJ.Theuseofgene-targetedmiceincontacthypersensitivityresearch.CvaniA,GirolomoniG.MedIntell.pp.83-90.2005.

3. SauderDN,BergfeldWF,KrakauerRS.Disodiumcromoglycateinmastocytosis.TheMastCell,ItsRoleinHealthandDisease.Eds.,J.Pepys,AMEdwards:PitmanMedical.pp.591-596,1979.

4. SauderDN,BergfeldWF.Alopeciaareata:Aninheritedautoimmunedisorder.Hairtraceelementsandhumanillness.Praeger,BrownandCrounse.pp.343-347,1980.

5. SauderDN,NoonanFP,DeFaboEC,KatzSI.EffectofUVradiationonalloantigenpresentationandonepidermalcellderivedthymocyteactivatingfactor(ETAF).In:Theeffectofultravioletradiationontheimmunesystem.Parrish,JA(Ed),Johnson&Johnson,1983.

6. SauderDN,RosenthalD.CutaneousTcelllymphomainCurrentTherapyinHematology-Oncology,pages91-94,1985-86.

7. GransteinRD,MargolisR,MizelSB,SauderDN.ChemotacticActivityofEpidermalcell-derivedthymocyteactivatingfactor(ETAF)andimmunologicalactionsofinterleukin-1.AlanR.Liss,NewYork,pages25-30,1985.


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8. GauldieJ,SauderDN,McAdamKPWJ,DinarelloCA.PurifiedhumanmonocyteIL-1stimulateshepatocytesecretionofmultipleacutephaseproteinsinvitroin:ThePhysiologic,MetabolicandImmunologicalActionsofInterleukin-1.AlanR.Liss,NewYork,pages221-229,1985.

9. SauderDN.Epidermalcell-derivedthymocyteactivatingfactor(ETAF):AmediatorofinflammatoryandimmunereactionsinThePhysiologic,MetabolicandImmunologicalActionsofInterleukin-1.AlanR.Liss,NewYork,pages365-373,1985.

10. SauderDN.AllergicContactDermatitisinPathogenesisofSkinDisease,ChurchillLivingstoneInc.B.H.ThiersandRLDobson,Editors,pp.3-12,1986.

11. SauderDN.Epidermalcellthymocyteactivatingfactor-advancesindermatology.Editors,JPCallen,MVDahl,LEGolitz,JERasmussenandSJStigman.YearBookMedicalPublishersInc.,Chicago,Vol.1:237-246,1986

12. SauderDN.Effectofageonepidermalimmunefunction.In:DermatologicClinics,Vol.4:pages447-454,Gilchrest,B.(ed),W.B.SaundersCo.,1986

13. SauderDN.EffectofAgeonEpidermalImmuneFunction.In:CutaneousAging.A.M.KligmanandY.Takase(eds.),B.A.Gilchrest,J.J.Nordlund(assoc.eds.),UniversityofTokyoPress.1988.

14. SauderDN.Interleukins.In:BiochemistryandPhysiologyoftheSkin,2ndedition.OxfordPress.LowellGoldsmitheditor,1989.

15. SauderDN.EffectofAgeonEpidermalImmuneFunction.In:ClinicsinGeriatricMedicine,GeriatricDermatology,B.A.Gilchresteditor,W.B.SaundersCo.,Philadelphia,PA,5:1,pp.149-160,1989

16. SauderDN.InductiveEffectsofImmunologicalCytokinesintheSkinIn:ImmuneMechanismsinCutaneousDisease,D.A.NorrisEditor,MarcelDekker,Inc.,NewYork,N.Y.pp.98-101,1989

17. SauderDN.Interleukin-1indermatologicdisease.In:Interleukin-1,InflammationandDisease.R.BomfordandB.Henderson(eds.)JT.DingleandJL.Gordon(gen.eds.)ElsevierSciencePublishersB.V.pp.257-266,1989.

18. McKenzieRC,SauderDN.Keratinocytecytokinesandgrowthfactors:Functionsinskinimmunityandhomeostasis.In:DermatologicClinics,D.N.Sauder(ed.),Vol.8(4)pp.1-13,Octoberl990.

19. SauderDN.Theskinasanimmunologicorgan.In:PathophysiologyofDermatologicDiseases,2ndEdition.SoterandBaden(eds).Chapter7,pp.101-110,1990.


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20. PaganelliParkerK,KilianPL,SauderDN.PresenceofInterleukin-1inReceptorsonKeratinocytes.In:Endocrine,MetabolicandImmunologicFunctionsofKeratinocytes,L.M.MilstoneandR.L.Edelson(eds.).AnnalsoftheNewYorkAcademyofScience,NewYork,N.Y.,Vol.548,346-347,1990.

21. TronVA,SauderDN.AllergicContactDermatitis.In:ImmunologicDiseasesoftheSkin.R.E.Jordon(ed.)Appleton&Lange,Norwalk,Conn.pp.253-261,1990.

22. McKenzieRC,ArsenaultTV,DanhoW,KilianPL,SauderDNandHarleyCB.IdentificationandPartialCharacterizationofaNovelGeneExpressingInterleukin-1ActivityinKeratinocytes.In:MolecularandCellularBiologyofCytokines,Oppenheimetal.(ed.).AlanR.Liss,NewYork,Vol.10A,pp.13-17,1990.

23. NozakiS,SauderDN.ImmuneFunctionofKeratinocytes.In:CellularandCytokineNetworksinTissueImmunity.M.MeltzerandA.Mantovani(eds.)Wiley-Liss,NewYork,N.Y.pp.49-54,1991.

24. NozakiS,FelicianiC,SauderDN.KeratinocyteCytokines.In:AdvancesinDermatology,Volume7.J.P.CallenandM.V.Dahl(eds.)Mosby-YearBook,Inc.,Chicago,Illinois.pp.83-101,1991.

25. ShivjiGM,GuptaAK,SauderDN.RoleofCytokinesinIrritantcontactdermatitis,inInvitroSkinToxicology:Methodsinirritation,phototoxicity,sensitization,(eds.)RougierA,GoldbergAM,MaibachHI.Mary-AnnLiebert,Inc.NewYork,FirstEdition.10:13-22,1994.

26. GuptaAK,JambrosicJ,RosenthalD,SauderDN.CutaneousTCellandBCellLymphomas.In:CurrentTherapyinHematology-Oncology.Mosby-YearBook,Inc.,St.Louis,Missouri,FifthEdition.288-292,1994.

27. CaughmanWR,SauderDN.Mechanisms,Symptoms,andTreatmentofInflammation.PathwaysofInflammation.(eds.)ArndtK,LeBoitP,RobinsonJ,andWintroubBU."CutaneousMedicineandSurgery”Chapter7,141-153,1995.

28. FelicianiC,GuptaAK,SauderDN.KeratinocytesandCytokine/GrowthFactors,inCriticalReviewsinOralBiology&Medicine,(ed.)AlvaresOF.AmericanAssociationofOralBiologists,6thEdition.Vol.VII,Issue4:300-318,1996.

29. GuptaAK,PrussickR,ShivjiGM,SauderDN.Cytokines,inImmunomodulatoryandCytotoxicAgentsinDermatology.(ed.)McDonaldCJ,MarcelDeckerInc.,NewYork.FirstEdition.Chapter8,pp71-123,1997.

30. DytocM,SauderDN.Cytokines.(ed)CallenJP."CurrentProblemsinDermatology"Vol.9,No.1,pp1-32,1997.


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31. DytocM,SauderDN.CutaneousCarcinogenesis:CytokinesandGrowthFactors.(ed.)MillerSJ.CutaneousOncology,1997.

32. SauderDN,FelicianiC.TheSkinasanImmunologicOrgan:RoleofEpidermalCytokines.In:AlternativeMethodsinToxicology,Volume8,(ed.)GoldbergA.MarianneLiebert,Inc.,NewYork,N.Y,1997.

33. DytocM,SauderDN.Cytokinetherapyinskindisorders.DermatologicTherapy.Volume5,1998,34-47.

34. GuptaAK,SauderDN.Theuseofcyclosporinetotreatcutaneousdiseases.DermatologicTherapy.P518-528,1997.

35. MydlarskiPR,KatzAM,SauderDN.ContactDermatitis.Allergy:PrincipalsandPractice.Edition5,Chapter81,1998.

Abstracts

1. DeBenedettoA,MamelakAJ,WangB,ShinT,CumminsDL,KoubaDJ,EscheC,FreedI,TulliA,BeckL,PardollDMandSauderDN.VariableexpressionoftheB7costimulatorymoleculefamilyonnormalhumankeratinocytes.JournalofInvestigativeDermatology2004;122(3):765.

2. WangB,ShinT,WatanabeH,FreedI,HowellB,MamelakA,EscheC,KoubaD,DeBenedettoA,CumminsD,PardollDandSauderD.DifferentialexpressionofB7-DCbyLangerhanscellsandkeratinocytes-aduelroleforB7-DCinskinimmunity.JournalofInvestigativeDermatology2004;122(3):740.

3. EscheC,PfohlerC,BenoitN,RosenbaumE,WangB,MamelakAJ,CumminsDL,DeBenedettoA,FreedI,TilgenW,BalchCM,SauderDNandSidranskyD.FirststudyonBRAFmutationintheserumofmelanomapatients.JournalofInvestigativeDermatology2004;122(3):553.

4. MamelakAJ,KowalskiJ,YadavaN,MurphyK,CumminsDL,KoubaDJ,DeBenedettoA,FreedI,EscheC,WangB,SchefflerIE,BergKandSauderDN.Correlativeanalysisofmicroarraysforcharacterizingbasalcellcarcinoma:NDUFA1andtheanaerobictumorenvironment.JournalofInvestigativeDermatology2004;122(3):156.

5. WangB,BackmanSA,FreedI,CaiQC,WatanabeH,HowellBGetal.AccumulationofLangerhanscellsintheskinofepithelium-specificPTENknockoutmice.JournalofInvestigativeDermatology2001;117(4):1009.


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6. FelicianiC,TotoP,WangB,TulliA,SauderDN.CDSlymphocytesareinvolvedinthepathogenesisofacantholysisinvivo.JournalofInvestigativeDermatology2001;117(3):779.

7. WangBH,SauderDN.FcRgammarepresentstheFcreceptorgammachainwhereasFcgammaRmeanstheFcreceptorforIgG.JournalofInvestigativeDermatology2001;116(2):350.

8. SauderDN,WangBH.RoleofcytokinesofepidermalLangerhanscellmigration.JournalofInvestigativeDermatology2000;114(1):225.

9. FelicianiC,TotoP,AmerioP,PourSM,CoscioneG,ShivjiGetal.IL-101alphaandTNF-01alphaarethemaincytokineinvolvedinacantholysis.JournalofInvestigativeDermatology1999;112(4):614.

10. SuzukiH,WangB,ShivjiGM,TotoP,AmerioP,TomaiMAetal.Imiquimod,atopicalimmuneresponsemodifier,inducesmigrationofLangerhanscells.JournalofInvestigativeDermatology1999;112(4):628.

11. ZhuangLH,WangBH,SauderDN.Tumornecrosisfactorreceptorp55playsapivotalroleinUVB-inducedkeratinocyteapoptosis.JournalofInvestigativeDermatology1998;110(4):505.

12. TotoP,AmerioP,FelicianiC,SuzukiH,ShivjiG,WoodleyDetal.Theroleofthecellularimmunesysteminthepathologyofpemphigusvulgarisacantholysis.JournalofInvestigativeDermatology1998;110(4):512.

13. WangB,ZhuangL,FujisawaH,SauderDN.EffectofIL-10deficiencyonthemigrationofepidermalLangerhanscellsinIL-10nullmice.JournalofInvestigativeDermatology1998;110(4):562.

14. SuzukiH,WangB,AmerioP,TotoP,ShivjiG,MillerRetal.Imiquimod,anoveltopicalimmuneresponsemodifierinducesmigrationofLangerhanscells.JournalofInvestigativeDermatology1998;110(4):566.

15. O'TooleEA,GordonKB,KhannaVJ,KondoS,SauderDN,WoodleyDT.TypeIcollageninductionofinterleukin-8inmigratingkeratinocytesismediatedbythebeta1integrinreceptor.JournalofInvestigativeDermatology1998;110(4):593.

16. AmerioP,ProiettoG,FelicianiC,TotoP,ShivjiGM,LoconsoleFetal.ExpressionofeotaxinmRNAinAIDS-associatedEosinophilicFolliculitis.JournalofInvestigativeDermatology1998;110(4):656.

17. AmerioP,TotoP,FelicianiC,SuzukiH,ShivjiG,SauderDN.EffectofgenetargetedmutationinTNFreceptor1andreceptor2onultravioletB-induced


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immunosuppressionandtolerance.JournalofInvestigativeDermatology1998;110(4):689.

18. OtooleEA,KhannaVJ,KondoS,GordonKB,SchallTJ,SauderDNetal.CellmotilityandhypoxiadramaticallyincreasethesecretionofIL-8byhumankeratinocytes.JournalofInvestigativeDermatology1997;108(4):272.

19. ZhuangL,WangB,ShivjiGM,BordelieuR,SavardP,FalideauPetal.AE-941,anovelinhibitorofangiogenesishassignificantanti-inflammatoryeffectoncontacthypersensitivity.JournalofInvestigativeDermatology1997;108(4):575.

20. KondoS,SauderDN,JimbowK.TNF-receptortype1(p55)isamainmediatorforTNFalpha-inducedskininflammation.JournalofInvestigativeDermatology1997;108(4):599.

21. ShivjiGM,WangB,ZhuangL,FujisawaH,SauderDN.CytokineprofilesintheinductionphaseofcontacthypersensitivityinIL-10gene-targetedmutantmice.JournalofInvestigativeDermatology1997;108(4):624.

22. FujisawaH,OtsukaF,SauderDN.Theexpressionandmodulationofinterferon(IFN)-alphaandIFN-betainhumankeratinocytes.JournalofInvestigativeDermatology1997;108(4):629.

23. KhannaVJ,OtooleEA,SchallTJ,KondoS,SauderDN,WoodleyDT.AcollagenmatrixandcellularmotilitydramaticallyincreasethesecretionofIL-8byhumankeratinocytes.JournalofInvestigativeDermatology1996;106(4):166.

24. WangB,KondoS,ShivjiGM,FujisawaH,MakTW,SauderDN.TumornecrosisfactorreceptorII(p75)signallingisrequiredforLangerhanscellmigration.JournalofInvestigativeDermatology1996;106(4):447.

25. OdaY,TimpeL,McKenzieRC,SauderDN,LargmanC,MauroT.AlternativelysplicedisoformsofcGMP-gatedcationchannelfromhumankeratinocytes.JournalofInvestigativeDermatology1996;106(4):592.

26. KondoS,KoosheshF,WangB,FujisawaH,SauderDN.ContributionofCD28moleculetoallergicandirritantinducedskinreactionsusinggene-targetedmutantmice.JournalofInvestigativeDermatology1996;106(4):721.

27. FujisawaH,KondoS,WangB,ShivjiGM,SauderDN.CostimulationswithultravioletBandinterleukin-1alphadramaticallyincreasetumornecrosisfactor-alphaproductioninhumandermalfibroblasts.JournalofInvestigativeDermatology1996;106(4):786.


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28. ShivjiGM,ZielinskaE,KondoS,MukhtarH,SauderDN.Anti-inflammatoryeffectofgreenteapolyphenolsonculturednormalhumankeratinocytes.JournalofInvestigativeDermatology1996;106(4):787.

29. OdaY,TimpeLC,McKenzieRC,SauderDN,LargmanC,MauroT.AlternativelysplicedformsofthecGMP-gatedchannelinhumankeratinocytes.FebsLetters1997;414(1):140-145.

30. KhannaVJ,OtooleEA,SchallTJ,KondoS,SauderDN,WoodleyDT.ACollagenMatrixandCellularMotilityDramaticallyIncreasetheSecretionofIl-8byHumanKeratinocytes.JournalofInvestigativeDermatology1995;104(4):591.

31. WangB,KondoS,ShivjiGM,MakTK,SauderDN.EpidermalGamma-DeltaT-CellsDevelopNormallyinCd4GeneTargetedMutantMice.JournalofInvestigativeDermatology1995;104(4):615.

32. ShivjiGM,KhatauS,KondoS,SegalL,SauderDN.EffectsofAlcoholsonViability,MembraneIntegrityandCytokineMessageinCulturedNormalHumanKeratinocytes.JournalofInvestigativeDermatology1995;104(4):652.

33. FujisawaH,KondoS,ShivjiGM,SauderDN.CytokineProfilesintheSkinandLymph-NodesinCd4GeneTargetedMouseFollowingHaptenApplication.JournalofInvestigativeDermatology1995;104(4):652.

34. VennerTJ,SauderDN,McKenzieRC.TheImmediate-EarlyGeneResponsetoUltraviolet-B(Uvb)RadiationinHumanKeratinocytes-Interleukin-1IsNottheTrigger.JournalofInvestigativeDermatology1994;102(4):538.

35. KonoT,KondoS,PastoreS,WallaceVA,PaigeCJ,MakTWetal.SkinCytokineProfilesinTight-Skin(Tsk)MicewithCd4OrCd8GeneDisruption.JournalofInvestigativeDermatology1994;102(4):548.

36. KondoS,KonoT,PastoreS,MakTW,BeissertS,GransteinRetal.Cd4andCd8RequiredforOptimalSensitizationandElicitationofAllergicContact-Dermatitis.JournalofInvestigativeDermatology1994;102(4):629.

37. McKenzieRC,OranA,KondoS,MarshallJS,PagliaD,SauderDN.FurtherAntiinflammatoryActionsofCyclosporine-ATreatment-ReductionofDermalMast-CellNumbersandReductioninOcam-1ProteinExpressioninAsebiaMice.JournalofInvestigativeDermatology1994;102(4):634.

38. PagliaD,KonoT,BennetF,TurnerK,LuC,KerbelRetal.ExpressionofLeukemiaInhibitoryFactor(Lif)andInterleukin-11(Il-11)byHuman-MelanomaLines-Lif,Il-6andIl-11AreNotCoregulated.JournalofInvestigativeDermatology1994;102(4):643.


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39. PagliaD,KonoT,BennettF,TurnerK,LuC,KerbelRSetal.ExpressionofLeukemiaInhibitoryFactor(Lif)andInterleukin-11(Il-11)byHuman-MelanomaCell-Lines-Il-6,Il-11AreNotCoregulated.JournalofInvestigativeDermatology1994;103(2):271.

40. SauderDN,KonoT,KondoS,PastoreS,WallaceVA,PaigeCJetal.SkinCytokineProfilesinTight-Skin(Tsk)MicewithCd4OrCd8GeneDisruption.JournalofInvestigativeDermatology1994;103(2):272.

41. KondoS,ShivjiGM,KonoT,PastoreS,MakTW,SauderDN.Cd4andCd8RequiredforOptimalDevelopmentofAllergicContact-Dermatitis.JournalofInvestigativeDermatology1994;103(2):272.

42. KondoS,McKenzieRC,CiarlettaA,TurnerK,SauderDN.HumanKeratinocytesdoNotProduceIl-3Messenger-RnaandProtein-AntibodiestoGm-CsfandIl-6(ButNotIl-3)NeutralizeIl-3Bioactivity.ClinicalResearch1994;42(2):A231.

43. MarshallJS,KadelastolarzU,VennerTJ,MakT,SauderDN,McKenzieRC.MicewithDisruptedCd4GenesHaveIncreasedNumbersofMast-CellsintheSkin.ClinicalResearch1994;42(2):A232.

44. KondoS,KonoT,WallaceV,McKenzieRC,PaigeCJ,MakTWetal.Cd4LymphocytesRequiredforSclerodermaPhenotypeinTskGeneTargetedMutantMice.JournalofInvestigativeDermatology1993;100(4):498.

45. PagliaD,SauderDN,McKenzieRC.IdentificationofLeukemiaInhibitoryFactor(Lif)inNormalandMalignantHumanSkinandCell-Lines.JournalofInvestigativeDermatology1993;100(4):522.

46. HunerHO,McKenzieRC,SauderDN.TheCloningandSequencingofANovelCdnafromHumanKeratinocyteswithHomologytoACgmp-GatedIonChannel.JournalofInvestigativeDermatology1993;100(4):524.

47. KondoS,KonoT,BrownWR,McKenzieRC,SauderDN.Cell-AdhesionMoleculeRequirementforElicitationofContactHypersensitivity.JournalofInvestigativeDermatology1993;100(4):563.

48. ShivjiGM,KulkarniSV,SegalL,SauderDN.SurfactantInducedToxicity,Arachidonic-AcidReleaseandCytokineMessenger-RnaProfileofCulturedHumanKeratinocytes.JournalofInvestigativeDermatology1993;100(4):568.

49. KonoT,KondoS,SauderDN,McKenzieRC.InhibitionofCytokineGene-ExpressionbySubcutaneousInjectionofCyclosporineinMouseSkin.JournalofInvestigativeDermatology1993;100(4):569.


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50. McKenzieRC,SauderDN,DinarelloC.InhibitionofB16-MelanomaGrowth-InvivoAfterTreatmentwithInterleukin-1ReceptorAntagonist.JournalofInvestigativeDermatology1993;100(4):570.

51. PagliaD,SauderDN,McKenzieRC.IdentificationofLeukemiaInhibitoryFactor(Lif)inNormalandMalignantHumanSkinandCell-Lines.ClinicalResearch1993;41(2):A179.

52. HunerHO,McKenzieRC,SauderDN.TheCloningandSequencingofANovelCdnafromHumanKeratinocyteswithHomologytoACgmp-GatedIonChannel.ClinicalResearch1993;41(2):A440.

53. KondoS,KonoT,BrownWR,McKenzieRC,SauderDN.Cell-AdhesionMoleculeRequirementforElicitationofContactHypersensitivity.ClinicalResearch1993;41(2):A456.

54. KondoS,KonoT,WallaceV,McKenzieRC,PaigeCJ,MakTWetal.Cd4-LymphocytesRequiredforSclerodermaPhenotypeinTskGeneTargetedMutantMice.ClinicalResearch1993;41(2):A456.

55. KonoT,KondoS,SauderDN,McKenzieRC.InhibitionofCytokineGene-ExpressionbySubcutaneousInjectionofCyclosporineinMouseSkin.ClinicalResearch1993;41(2):A463.

56. McKenzieRC,SauderDN,DinarelloC.InhibitionofB16MelanomaGrowth-InvivoAfterTreatmentwithInterleukin-1ReceptorAntagonist.ClinicalResearch1993;41(2):A464.

57. ShiviiGM,KulkarniSV,SegalL,SauderDN.Surfactant-InducedToxicity,Arachidonic-AcidReleaseandCytokineMessenger-RnaProfileofCulturedHumanKeratinocytes.ClinicalResearch1993;41(2):A467.

58. McKenzieRC,FelicianiC,VennerTJ,SauderDN.InductionofMelanomaGrowth-FactorsinKeratinocytesbyUvbandInterleukin-1.ClinicalResearch1992;40(2):A471.

59. McKenzieRC,ParkES,ShivjiGM,BrownWR,SauderDN.EffectsofUvb-InducibleCytokinesonMelanomaGrowth-InvivoandInvitro.ClinicalResearch1992;40(2):A471.

60. NgKME,MckenizeRC,SauderDN.LeukemiaInhibitoryFactor(AStem-CellsGrowth-Factor)IsInducedbyUvbIrradiationinHumanKeratinocytes.ClinicalResearch1992;40(2):A472.

61. ShivjiGM,StetskoDK,SauderDN.EpidermalCytokineGene-Expression-AnInvitroAssayforIrritantsandAllergens.ClinicalResearch1992;40(2):A474.


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62. McKenzieRC,HunerHO,SauderDN.IdentificationandCharacterizationofANovelNucleotide-GatedIonChannelinHumanKeratinocytes.ClinicalResearch1992;40(2):A491.

63. BrownWR,TakeiF,SauderDN.AdhesionMoleculesinAllergicContactSensitization.ClinicalResearch1992;40(2):A496.

64. McKenzieRC,FelicianiC,VennerTJ,SauderDN.InductionofMelanomaGrowth-FactorsinKeratinocytesbyUvbandInterleukin-1.JournalofInvestigativeDermatology1992;98(4):565.

65. BrownWR,TakeiF,SauderDN.AdhesionMoleculesinAllergicContactSensitization.JournalofInvestigativeDermatology1992;98(4):596.

66. NgKME,MckenizeRC,SauderDN.LeukemiaInhibitoryFactor(AStem-CellsGrowth-Factor)IsInducedbyUvbIrradiationinHumanKeratinocytes.JournalofInvestigativeDermatology1992;98(4):612.

67. ShivjiGM,StetskoDK,SauderDN.EpidermalCytokineGene-Expression-AnInvitroAssayforIrritantsandAllergens.JournalofInvestigativeDermatology1992;98(4):613.

68. McKenzieRC,ParkES,ShivjiGM,BrownWR,SauderDN.EffectsofUvb-InducibleCytokinesonMelanomaGrowth-InvivoandInvitro.JournalofInvestigativeDermatology1992;98(4):613.

69. McKenzieRC,HunerHO,SauderDN.IdentificationandCharacterizationofANovelNucleotide-GatedIonChannelinHumanKeratinocytes.JournalofInvestigativeDermatology1992;98(4):627.

70. McKenzieRC,LeaRG,SauderDN.Ultraviolet-RadiationInducesExpressionofInterleukin8andTransformingGrowth-Factor-BetainHumanKeratinocytes.ClinicalResearch1991;39(2):A519.

71. McKenzieRC,WonY,SauderDN.InhibitionofKeratinocyteCytokineExpressionbyCyclosporine-A.ClinicalResearch1991;39(2):A519.

72. NozakiS,SauderDN.Ultraviolet-IrradiationDown-RegulatesIl-1ReceptorinPam-212Keratinocytes.ClinicalResearch1991;39(2):A519.

73. McKenzieRC,WonY,SauderDN.InhibitionofKeratinocyteCytokineExpressionbyCyclosporine-A.JournalofInvestigativeDermatology1991;96(4):537.

74. NozakiS,SauderDN.Ultraviolet-IrradiationDown-RegulatesIl-1ReceptorinPam-212Keratinocytes.JournalofInvestigativeDermatology1991;96(4):609.


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75. McKenzieRC,LeaRG,SauderDN.Ultraviolet-RadiationInducesExpressionofInterleukin-8andTransformingGrowth-Factor-BetainHumanKeratinocytes.JournalofInvestigativeDermatology1991;96(4):610.

76. McKenzieRC,HarleyCB,MaticS,SauderDN.NormalHumanSerumandFetalBovineSerumContainAnIl-1Inhibitor.ClinicalResearch1990;38(2):A647.

77. SauderDN,MaticS,FongD,DuronioV.AutocrineStimulationofKeratinocytesbyInterleukin-3(Il-3)-MurineKeratinocytesPossessIl-3Receptors.ClinicalResearch1990;38(2):A648.

78. McleanJ,FelicianiC,RosenthalD,ChristophersE,SticherlingM,SchroderJMetal.Interleukin-8ImmunoreactivityinPatientswithCutaneousT-CellLymphoma.ClinicalResearch1990;38(2):A686.

79. GalloRL,SauderDN,KniselyTL,GransteinRD.ModulationofGm-CsfandIl-3ProductionbyAMurineKeratinocyteCell-LineFollowingUltraviolet-RadiationExposure.JournalofInvestigativeDermatology1990;94(4):527.

80. McKenzieRC,HarleyCB,MaticS,SauderDN.NormalHumanSerumandFetalBovineSerumContainAnIl-1Inhibitor.JournalofInvestigativeDermatology1990;94(4):554.

81. McleanJ,FelicianiC,RosenthalD,ChristophersE,SticherlingM,SchroderJMetal.Interleukin-8ImmunoreactivityinPatientswithCutaneousT-CellLymphoma.JournalofInvestigativeDermatology1990;94(4):555.

82. SauderDN,MaticS,FongD,DuronioV.AutocrineStimulationofKeratinocytesbyInterleukin3(Il-3)-MurineKeratinocytesPossessIl-3Receptors.JournalofInvestigativeDermatology1990;94(4):574.

83. SauderDN.TheRoleofEpidermalCytokinesinInflammationandImmunity.JournalofInvestigativeDermatology1989;93(4):575.

84. MertzPM,DavisSC,EaglsteinWH,KilianP,SauderDN.Interleukin-1IsAPotentInducerofWoundReepithelialization.ClinicalResearch1989;37(2):A677.

85. SauderDN,StetskoD,MckenzieR,HowardM,PearceMK,OgarraA.MolecularandFunctional-CharacterizationofKeratinocyteCytokineandIdentificationofAUniqueKeratinocyteCytokineThatInducesB-CellGrowth.ClinicalResearch1989;37(2):A695.

86. SwopeVB,AbdelmalekZA,SauderDN,NordlundJJ.EpidermalCytokinesDownregulatetheMelanogenicResponsivenessofMalignantandNormalMelanocytes.ClinicalResearch1989;37(2):A722.


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87. MertzPM,DavisSC,EaglsteinWH,KilianP,SauderDN.Interleukin-1IsAPotentInducerofWoundReepithelialization.JournalofInvestigativeDermatology1989;92(3):480.

88. SauderDN,StetskoD,MckenzieR,HowardM,PearceMK,OgarraA.MolecularandFunctional-CharacterizationofKeratinocyteCytokineandIdentificationofAUniqueKeratinocyteCytokineThatInducesB-CellGrowth.JournalofInvestigativeDermatology1989;92(3):512.

89. SwopeVB,AbdelmalekZA,SauderDN,NordlundJJ.EpidermalCytokinesDownregulatetheMelanogenicResponsivenessofMalignantandNormalMelanocytes.JournalofInvestigativeDermatology1989;92(3):525.

90. SauderDN,WongD,LaskinCA.UvInducedExacerbationinLupusIsMediatedbyCutaneousInterleukin-1.ClinicalResearch1988;36(3):A379.

91. CooperKD,BaadsgaardO,ElderJT,SauderDN,VoorheesJJ,FisherG.IncreasedLevelsofAnInterleukin-1InhibitorBlockInterleukin-1ActivityButNotImmunoreactivityOrMessenger-RnaExpressionofInterleukin-1BetainPsoriasisSkin.ClinicalResearch1988;36(3):A638.

92. FurukawaF,SawamiM,LyonsMB,SauderDN,NorrisDA.Ultraviolet-LightInductionofRoandlaAntigensonHumanKeratinocytes-ACrucialComponentofPhotosensitiveCutaneousLupus-Erythematosus.ClinicalResearch1988;36(3):A647.

93. RheinsLA,CotleurAL,KleierRS,HoppenjansWB,SauderDN,NordlundJJ.Alpha-MelanocyteStimulatingHormoneActsAsAnImmuneModulatoroftheContactHypersensitivityResponseinC57Bl/6Mice.ClinicalResearch1988;36(3):A688.

94. SauderDN,WongD,MckenzieR,StetskoD,HarnishD,TronVetal.ThePluripotentKeratinocyte-MolecularCharacterizationofEpidermalCytokines.ClinicalResearch1988;36(3):A692.

95. SwopeVB,AbdelmalekZA,SauderDN,NordlundJJ.ANewRoleforEpidermalThymocyteActivatingFactorAsAModulatorofANon-ImmunologicEpidermalFunction.ClinicalResearch1988;36(3):A697.

96. TronVA,CoughlinM,SauderDN.KeratinocytesSynthesizeandExpressNerveGrowth-Factor-PotentialMechanismforMelanomaGrowth.ClinicalResearch1988;36(3):A700.

97. CooperKD,BaadagaardO,ElderJT,SauderDN,VoorheesJJ,FisherG.IncreasedLevelsofAnInterleukin-1InhibitorBlockInterleukin-1ActivityButNotImmunoreactivityOrMessenger-RnaExpressionofInterleukin1-BetainPsoriasisSkin.JournalofInvestigativeDermatology1988;90(4):552.


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98. FurukawaF,SawamiM,LyonsMB,SauderDN,NorrisDA.Ultraviolet-LightInductionofRoandlaAntigensonHumanKeratinocytes-ACrucialComponentofPhotosensitiveCutaneousLupus-Erythematosus.JournalofInvestigativeDermatology1988;90(4):561.

99. RheinsLA,CotleurAL,KleierRS,HoppenjansWB,SauderDN,NordlundJJ.Alpha-MelanocyteStimulatingHormoneActsAsAnImmuneModulatoroftheContactHypersensitivityResponseinC57Bl/6Mice.JournalofInvestigativeDermatology1988;90(4):601.

100. SauderDN,WongD,MckenzieR,StetskoD,HarnishD,TronVetal.ThePluripotentKeratinocyte-MolecularCharacterizationofEpidermalCytokines.JournalofInvestigativeDermatology1988;90(4):605.

101. SwopeVB,AbdelmalekZA,SauderDN,NordlundJJ.ANewRoleforEpidermalThymocyteActivatingFactorAsAModulatorofANon-ImmunologicEpidermalFunction.JournalofInvestigativeDermatology1988;90(4):611.

102. TronVA,CoughlinM,SauderDN.KeratinocytesSynthesizeandExpressNerveGrowth-Factor-PotentialMechanismforMelanomaGrowth.JournalofInvestigativeDermatology1988;90(4):613.

103. SauderDN,KilianPL.Cell-SurfaceReceptorsforInterleukin-1ArePresentonHumanKeratinocytes.ClinicalResearch1987;35(3):A390.

104. TronVA,SauderDN.InsituDetectionofInterleukin-1Messenger-Rna-ASensitiveTechniquetoDetectCytokinesinTissue.ClinicalResearch1987;35(3):A391.

105. BushLE,HarperPA,SauderDN,ShearNH.AcetaminophenToxicitytoKeratinocytesInvitroAssessedbyANovelAssay.ClinicalResearch1987;35(3):A673.

106. SauderDN,ArsenaultTV,StetskoD,HarleyCB.IsolationandPartialCharacterizationofAPutativeEtafCdnaClone(Kil-1)-EtafIsDistinctfromIl-1-AlphaOrIl-1-Beta.ClinicalResearch1987;35(3):A714.

107. SauderDN,GuyD,DamjiN,OrrFW,ClarkeDA.InvivoandInvitroEffectsofEpidermalThymocyteActivatingFactoronTumor-GrowthandTumor-CellChemotaxis.ClinicalResearch1987;35(3):A714.

108. TronVA,RosenthalD,SauderDN.EpidermalInterleukin-1IsIncreasedinCutaneousT-CellLymphoma-InsituLocalizationofInterleukin-1.ClinicalResearch1987;35(3):A722.


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109. SauderDN,GuyD,DamjiiN,OrrFW.InvivoandInvitroEffectsofEpidermalThymocyteActivatingFactoronTumor-GrowthandTumor-CellChemotaxis.JournalofCellularBiochemistry1987;87.

110. BellTV,HarleyCB,StetskoD,SauderDN.ExpressionofMessenger-RnaHomologoustoInterleukin-1inHumanEpidermal-Cells.JournalofInvestigativeDermatology1987;88(4):375-379.

111. BushLE,HarperPA,SauderDN,ShearNH.AcetaminophenToxicitytoKeratinocytesInvitroAssessedbyANovelAssay.JournalofInvestigativeDermatology1987;88(4):480.

112. SauderDN,ArsenaultTV,StetskoD,HarleyCB.IsolationandPartialCharacterizationofAPutativeEtafCdnaClone(Kil-1)-EtafIsDistinctfromIl-1-AlphaOrIl-1-Beta.JournalofInvestigativeDermatology1987;88(4):515.

113. SauderDN,GuyD,DamjiN,OrrFW,ClarkeDA.InvivoandInvitroEffectsofEpidermalThymocyteActivatingFactoronTumor-GrowthandTumor-CellChemotaxis.JournalofInvestigativeDermatology1987;88(4):515.

114. TronVA,SauderDN.EpidermalInterleukin-1IsIncreasedinCutaneousT-CellLymphoma-InsituLocalizationofInterleukin-1.JournalofInvestigativeDermatology1987;88(4):522.

115. SauderDN,BellTV,StetskoD,HarleyCB.HumanandMurineKeratinocytesContainMessenger-RnaHomologoustoInterleukin-1(Il-1).JournalofLeukocyteBiology1986;40(3):298.

116. RosenthalKL,RosenthalD,AitkenCL,SauderDN.LackofDetectableRetrovirusinCulturedPeripheral-BloodT-CellsfromPatientswithCutaneousT-CellLymphoma.ClinicalResearch1986;34(2):A418.

117. SauderDN,MarceloCL,KragballeK.FormationofEpidermal-CellThymocyteActivatingFactor(Etaf)fromCulturedHumanKeratinocytesfromNormalandUninvolvedPsoriaticSkin.ClinicalResearch1986;34(2):A418.

118. SauderDN,BellTV,HarleyCB.ExpressionofAnMessenger-RnaHomologoustoHumanBeta-Interleukin-1inHumanEpidermal-Cells.ClinicalResearch1986;34(2):A779.

119. SauderDN,BellTV,HarleyCB.ExpressionofAnMessenger-RnaHomologoustoHumanBeta-Interleukin-1inHumanEpidermal-Cells.JournalofInvestigativeDermatology1986;86(4):504.


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120. SauderDN.Epidermal-CellDerivedThymocyteActivatingFactorAsAMediatorofInflammatoryandImmune-Reactions.ClinicalandExperimentalDermatology1986;11(2):206.

121. BellTV,HarleyCB,SauderDN.HumanKeratinocytesContainMessenger-RnaHomologoustoHumanBeta-Interleukin-1(Beta-Il-1).FederationProceedings1986;45(4):942.

122. DenburgJA,SauderDN.GranulocyteColonyStimulatingActivityDerivedfromHumanKeratinocytes.LymphokineResearch1986;5(4):261-274.

123. StricklandJE,AllenPT,SauderDN,KawamuraH,FongMC,YuspaSH.InvitroComparisonsofSencarandBalb/CPrimaryEpidermal-Cells.EnvironmentalHealthPerspectives1986;68:39-44.

124. BarrRD,SauderDN,BienenstockJ.InteractionsofStem-CellsandLymphocytes-TContributetothePhysiologicalControlofCell-ProliferationinRapidlyRenewingTissues.MedicalHypotheses1986;19(4):387-396.

125. GransteinRD,MargolisR,MizelSB,SauderDN.InvivoInflammatoryActivityofEpidermal-CellDerivedThymocyteActivatingFactorandRecombinantInterleukin-1intheMouse.JournalofClinicalInvestigation1986;77(3):1020-1027.

126. ChoiKL,SauderDN.TheRoleofLangerhansCellsandKeratinocytesinEpidermalImmunity.JournalofLeukocyteBiology1986;39(3):343-358.

127. BaumannH,HillRE,SauderDN,JahreisGP.RegulationofMajorAcute-PhasePlasma-ProteinsbyHepatocyte-StimulatingFactorsofHumanSquamousCarcinoma-Cells.JournalofCellBiology1986;102(2):370-383.

128. SauderDN,MonickMM,HunninghakeGW.EpidermalCell-DerivedThymocyteActivatingFactor(Etaf)IsAPotentT-CellChemoattractant.JournalofInvestigativeDermatology1985;85(5):431-433.

129. WalkerIR,WilsonWEC,SauderDN,BengerAM,BrowmanG.Cytarabine-InducedPalmar-PlantarErythema.ArchivesofDermatology1985;121(10):1240-1241.

130. SauderDN.BiologicPropertiesofEpidermal-CellThymocyte-ActivatingFactor(Etaf).JournalofInvestigativeDermatology1985;85(1):S176-S179.

131. DenburgJA,SauderDN.HematopoieticColonyStimulatingActivityCo-PurifieswithEpidermal-CellThymocyteActivatingFactor.JournalofLeukocyteBiology1985;37(6):695.


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132. GransteinRD,MargolisRJ,MizelSB,SauderDN.InvivoChemotacticActivityofEpidermalCell-DerivedThymocyteActivatingFactor(Etaf)andInterleukin-1(Il-1)intheMouse.JournalofLeukocyteBiology1985;37(6):709.

133. PillaiPS,ReynoldsSD,ScottDW,SauderDN.TheInductionofGrowthandDifferentiationofB-CellsbyEpidermal-CellDerivedThymocyteActivatingFactor(Etaf).JournalofLeukocyteBiology1985;37(6):731.

134. SauderDN.Epidermal-CellDerivedThymocyteActivatingFactorAsAMediatorofInflammatoryandImmune-Reactions.JournalofLeukocyteBiology1985;37(6):739.

135. DenburgJA,MitchellEB,SauderDN.BasophilColonyGrowthStimulatedbyHumanKeratinocytes-PossibleRelevanceinAtopic-Dermatitis.ClinicalResearch1985;33(2):A160.

136. DenburgJA,SauderDN.HematopoieticColonyStimulatingActivityDerivedfromHumanKeratinocytes.ClinicalResearch1985;33(2):A633.

137. GransteinRD,MargolisRJ,SauderDN.InvivoChemotacticActivityofEpidermalCell-DerivedThymocyteActivatingFactor(Etaf)intheMouse.ClinicalResearch1985;33(2):A641.

138. GransteinRD,MargolisRJ,SauderDN.InvivoChemotacticActivityofEpidermalCell-DerivedThymocyteActivatingFactor(Etaf)intheMouse.JournalofInvestigativeDermatology1985;84(4):303.

139. DenburgJA,SauderDN.HematopoieticColonyStimulatingActivityDerivedfromHumanKeratinocytes.JournalofInvestigativeDermatology1985;84(4):304.

140. PillaiPS,ReynoldsSD,ScottDW,SauderDN.TheInductionofGrowthandDifferentiationofB-CellsbyEpidermal-CellDerivedThymocyteActivatingFactor(Etaf).FederationProceedings1985;44(4):972.

141. RobertsJ,SteadR,RosenthalD,TadrosA,JenkinP,BergerCetal.Be-1andBe-2Monoclonal-AntibodyReactivityinCutaneousT-CellLymphoma.JournalofInvestigativeDermatology1984;82(4):390.

142. SauderDN,MonickM,HunninghakeG.HumanEpidermal-CellDerivedThymocyteActivatingFactorIsAPotentT-CellChemoattractant.JournalofInvestigativeDermatology1984;82(4):399.

143. GilchrestBA,SauderDN.AutocrineGrowth-StimulationofHumanKeratinocytesbyEpidermalCell-DerivedThymocyteActivatingFactor(Etaf)-ImplicationsforCellularAging.JournalofInvestigativeDermatology1984;82(4):439.


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144. SauderDN,DinarelloCA,MorhennV.LangerhansCellProductionofInterleukin-1.ClinicalResearch1984;32(2):A258.

145. SauderDN,GeorgeBC,ClowesGHA.HumanEpidermal-CellDerivedCytokineStimulationofMuscleProteolysis.ClinicalResearch1984;32(2):A258.

146. GilchrestBA,SauderDN.AutocrineGrowth-StimulationofHumanKeratinocytesbyEpidermalCell-DerivedThymocyteActivatingFactor(Etaf)-ImplicationsforCellularAging.ClinicalResearch1984;32(2):A585.

147. RobertsJ,SteadR,RosenthalD,TadrosA,JenkinP,BergerCetal.Be1andBe2Monoclonal-AntibodyReactivityinCutaneousT-CellLymphoma.ClinicalResearch1984;32(2):A612.

148. SauderDN,MonickM,HunninghakeG.HumanEpidermal-CellDerivedThymocyteActivatingFactorIsAPotentT-CellChemoattractant.ClinicalResearch1984;32(2):A613.

149. StinglLA,SauderDN,IijimaM,WolffK,PehambergerH,StinglG.MechanismoftheUv-InducedImpairmentoftheAntigenPresentingCapacityofEpidermal-Cells.ArchivesofDermatologicalResearch1983;275(4):278.

150. SauderDN,MounessaNL,KatzSI,DinarelloCA,GallinJI.HomologousNatureofHumanLeukocyticPyrogenandEtaf.JournalofInvestigativeDermatology1983;80(4):304.

151. SauderDN,MounessaNL,KatzSI,DinarelloCA,GallinJI.HomologousNatureofHumanLeukocyticPyrogenandEtaf.ClinicalResearch1983;31(2):A600.

152. SauderDN,MounessaNL,KatzSI,DinarelloCA,GallinJI.ChemotacticCytokines-theRoleofLeukocyticPyrogenandEpidermal-CellThymocyte-ActivatingFactorinNeutrophilChemotaxis.JournalofImmunology1984;132(2):828-832.

153. NoonanFP,BucanaC,SauderDN,DefaboEC.MechanismofSystemicImmuneSuppressionbyUvIrradiationInvivo.2.theUvEffectsonNumberandMorphologyofEpidermalLangerhansCellsandtheUv-InducedSuppressionofContactHypersensitivityHaveDifferentWavelengthDependencies.JournalofImmunology1984;132(5):2408-2416.

154. SauderDN,NoonanFP,DefaboEC,KatzSI.Ultraviolet-RadiationInhibitsAlloantigenPresentationbyEpidermal-Cells-PartialReversalbytheSolubleEpidermal-CellProduct,EpidermalCell-DerivedThymocyte-ActivatingFactor(Etaf).JournalofInvestigativeDermatology1983;80(6):485-489.


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155. FisherRI,BostickbrutonF,SauderDN,ScalaG,DiehlV.Neoplastic-CellsObtainedfromHodgkins-DiseaseArePotentStimulatorsofHumanPrimaryMixedLymphocyte-Cultures.JournalofImmunology1983;130(6):2666-2670.

156. SauderDN,KatzSI.StrainVariationintheInductionofTolerancebyEpicutaneousApplicationofTrinitrochlorobenzene.JournalofInvestigativeDermatology1983;80(5):383-386.

157. StinglLA,SauderDN,IijimaM,WolffK,PehambergerH,StinglG.MechanismofUv-B-InducedImpairmentoftheAntigen-PresentingCapacityofMurineEpidermal-Cells.JournalofImmunology1983;130(4):1586-1591.

158. SauderDN,MounessaNL,KatzSI,DinarelloCA,GallinJI.ChemotacticPropertiesofHumanEtaf/Lp/Il-1.FederationProceedings1983;42(3):449.

159. StinglLA,SauderDN,IijimaM,WolffK,PehambergerH,StinglG.MechanismofUv-B-InducedImpairmentofEpidermalCell-InducedAntigen-SpecificT-CellActivation.Immunobiology1982;163(2-4):126.

160. SauderDN,KatzSI.ImmuneModulationbyEpidermal-CellProducts-PossibleRoleofEtafinInflammatoryandNeoplasticSkinDiseases.JournaloftheAmericanAcademyofDermatology1982;7(5):651-654.

161. SauderDN,CarterCS,KatzSI,OppenheimJJ.Epidermal-CellProductionofThymocyteActivatingFactor(Etaf).JournalofInvestigativeDermatology1982;79(1):34-39.

162. NoonanFP,BucanaC,SauderDN,DefaboEC.EffectofUltraviolet-RadiationonEpidermalLangerhansCellMorphologyandFunction-ADichotomy.ClinicalResearch1982;30(2):A600.

163. SauderDN,NoonanFP,DefaboEC,KatzSI.Uv-AlterationinAlloantigenPresentingAbilityofEpidermal-Cells-RestorationbytheSolubleEpidermal-CellProduct,Epidermal-CellDerivedThymocyteActivatingFactor(Etaf).ClinicalResearch1982;30(2):A607.

164. TamakiK,IijimaM,SauderDN,KatzSI.TheRoleofEpidermalLangerhansCellsintheInductionofAllergicContactSensitization.ClinicalResearch1982;30(2):A611.

165. SauderDN,NoonanFP,DefaboEC,KatzSI.UvAlterationinAlloantigenPresentingAbilityofEpidermal-Cells-RestorationbytheSolubleEpidermal-CellProduct,Epidermal-CellDerivedThymocyteActivatingFactor(Etaf).JournalofInvestigativeDermatology1982;78(4):337.


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166. NoonanFP,BucanaC,SauderDN,DefaboEC.EffectofUltraviolet-RadiationonEpidermalLangerhansCellMorphologyandFunction-ADichotomy.JournalofInvestigativeDermatology1982;78(4):345.

167. TamakiK,IijimaM,SauderDN,KatzSI.TheRoleofEpidermalLangerhansCellsintheInductionofAllergicContactSensitization.JournalofInvestigativeDermatology1982;78(4):353.

168. JakwayJP,SauderDN,ShevachEM.Ultraviolet(Uv)Light-InducedDefect(S)inPresentationofSoluble-ProteinAntigen.FederationProceedings1982;41(3):369.

169. SauderDN,CarterC,KatzSI,OppenheimJJ.Epidermal-CellProductionofThymocyteActivatingFactor.ClinicalResearch1981;29(2):A285.

170. SauderDN,TamakiK,FujiwaraH,MoshellAN,KatzSI.InductionofImmunologicalHyporesponsivenessUsingUltraviolet-LightIrradiatedHaptenatedEpidermal-Cells.ClinicalResearch1980;28(2):A253.

171. CalabreseLH,SauderDN,VerbicMA,KrakauerRS,CloughJD.Plasma-ExchangeinImmune-ComplexMediatedDisease.ClinicalResearch1980;28(1):A138.

C.GRANTSUPPORTPeer-Reviewed Operating Grants (Principal Investigator)

Organization: MedicalResearchCouncilProjecttitle: ImmunoregulatoryepidermalcytokinesPI: D.N.Sauder,M.D.Projectperiod: 1998-2003 TotalDirectCosts: $384,423.00

Organization: MedicalResearchCouncilProjecttitle: ImmunoregulatoryepidermalcytokinesininflammationPI: D.N.Sauder,M.D.Projectperiod: 1996-1998 TotalDirectCosts: $205,320.00

Organization: CanadianDermFoundationProjecttitle: InvitrohairpapillaeculturesforhumanhairtransplantationPI: D.N.Sauder,M.D.Projectperiod: 1998-1999 TotalDirectCosts: $10,000.00

Peer- Reviewed Operating Grants (Co-Investigator)

Organization: NationalInstituteofHealth


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ProjectTitle: ClassicalconditioninginPharmacotherapyofPsoriasisPI: FranciscoTausk,M.D.ProjectPeriod: 2004-2009 TotalDirectCosts: $481,921.00Organization: NationalInstituteofHealthProjectTitle: KeratinocyteCostimulationandTh2-cellimmunedeviationPI: AnthonyGaspari,M.D.Consultant: DanielN.Sauder,M.D.ProjectPeriod: 2004-2009Organization: NationalCancerInstituteProjectTitle: VaccinationinCombinationwithImatinibMesylateforChronic

MyeloidLeukemiaPI: HyamI.Levitsky,M.D.ProjectPeriod: 2004-2009 Organization: MedicalResearchCouncilProjecttitle: HighFrequencyDuplexUltrasoundInvestigationofMelanoma

ProgressionandAngiogenesisPI: S.Foster,M.D.Projectperiod: 1998-2004 TotalDirectCosts: $458,044.00Organization: CanadianDermatologyFoundationProjecttitle: MolecularMechanismforUVB-inducedkeratinocyteapoptosisPI: LihuaZhuang,M.D.Projectperiod: 1998-1999 TotalDirectCosts: $15,000.00

Organization: CanadianDermatologyFoundationProjecttitle: Modulationofcellularimmuneresponseinthepathogenesisof

pemphigusvulgarisPI: PaolaToto,M.D.Projectperiod: 1998-1999 TotalDirectCosts: $15,000.00

Organization: CanadianDermatologyFoundationProjecttitle: EffectofIL-10deficiencyonLangerhanscellmigrationand

cutaneousimmuneresponsesPI: BingheWang,M.D.Projectperiod: 1998-1999 TotalDirectCosts: $35,000.00


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Organization: OntarioCentreforMaterialsResearchProjecttitle: NovelbiodegradabledressingforchronicskinwoundsPI: K.Woodhouse,PhD.Projectperiod: 1998-1999 TotalDirectCosts: $105,000.00

Organization: MedicalResearchofCanada Projecttitle: UltrasoundbackscattermicroscopeforsuperficialskinimagingPI: F.S.Foster,M.D.Projectperiod: 1995-1998 TotalDirectCosts: $128,945.00



Organization: AllerganCanadaProjecttitle: RoleofIL-18inInductionandRegulationofCutaneousImmune

ResponsesPI: BingheWang,M.D.Projectperiod: 1999-2000 TotalDirectCosts: $50,000.00Organization: CanadianDermatologyFoundationProjecttitle: SignalingandmodulationofUV-inducedkeratinocyteapoptosisPI: LihuaZhuang,M.D.Projectperiod: 1999-2000 TotalDirectCosts: $10,000.00

Organization: CanadianDermatologyFoundationProjecttitle: Skin:ApotentialregulatorofCircadianRhythmPI: RegineMydlarski,M.D.Projectperiod: 1999-2000 TotalDirectCosts: $10,000.00

Organization: StiefelCanada


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Projecttitle: TheroleofTNFáandIL-10inUV-inducedskincarcinogenesisPI: HirotakeSuzuki,M.D.Projectperiod: 1999-2000 TotalDirectCosts: $25,000.00Organization: CanadianDermatologyFoundationProjecttitle: TheeffectofmelatoninonhumankeratinocyteapoptosisPI: SherineTavadia,M.D.Projectperiod: 1999-2000 TotalDirectCosts: $10,000.00

Non-Peer Reviewed Grant Support Organization: UnileverResearchU.S. Projecttitle: Highfrequencyultrasoundassessmentofskinelasticity PI: D.N.Sauder,M.D.

Projectperiod: 1995-1996 TotalDirectCosts: $132,340.00

Organization: LeverBrothers Projecttitle: Invitrosurfactantpenetrationstudythroughhumanskin

PI: D.N.Sauder,M.D.Projectperiod: 1995-1996 TotalDirectCosts: $81,000.00

Organization: HyalPharmaceuticals Projecttitle: Regulatoryeffectofhyaluranicacidinskininflammation PI: D.N.Sauder,M.D.


Organization: AeternaLesLaboratories Projecttitle: Effectofantiangiogenesisagentoncontactdermatitis PI: D.N.Sauder,M.D.


Organization: CibaVision

Projecttitle: Polymerlensaspotentialwounddressingandtransepidermaldelivery


Organization: 3MPharmaceuticals


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Projecttitle: EffectofR848onthehumanskin PI: D.N.Sauder,M.D. Projectperiod: 1996-1997 TotalDirectCosts: $103,000.00 Organization: CanadianDermatologyFoundation Projecttitle: Molecularanalysisofcytokines PI: D.N.Sauder,M.D.

Projectperiod: 1996-1997 TotalDirectCosts: $10,000.00Organization: Physicians'ServicesInc.Projecttitle: ImmunemodulationbyepidermalcellproductsincutaneousdiseasePI: D.N.Sauder,M.D.Projectperiod: 1982-1984 TotalDirectCosts: $66,000.00

Organization: CanadianDermatologyFoundationProjecttitle: EpidermalcytokinesfoundationandagingPI: D.N.Sauder,M.D.Projectperiod: 1985 TotalDirectCosts: $10,000.00

Organization: CanadianDermatologyFoundationProjecttitle: MolecularcloningofepidermalthymocyteactivatingfactorPI: D.N.Sauder,M.D.Projectperiod: 1986 TotalDirectCosts: $8,000.00

Organization: CanadianDermatologyFoundation

Projecttitle: ImmunoregulatoryepidermalcellproductsinUVinducedcarcinogenesis

PI: D.N.Sauder,M.D.Projectperiod: 1987 TotalDirectCosts: $14,700.00


Projecttitle: StudiesonthemechanismofUVinducedexacerbationsoflupuserythematosus

PI: D.N.Sauder,M.D.Projectperiod: 1988 TotalDirectCosts: $5,625.00


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Organization: NationalInstituteonAging(NIH)Projecttitle: ImmunoregulatoryepidermalfactorsinagingPI: D.N.Sauder,M.D.ProjectPeriod: 1984-1987 TotalDirectCosts: $106,964.00Organization: NationalInstitutesofHealth,NCIProjecttitle: ImmunoregulatoryepidermalfactorsinagingPI: D.N.Sauder,M.D.Projectperiod: 1986-1987 TotalDirectCosts: $36,000.00Organization: MinistryofHealth

Projecttitle: Clinicalwholebodyhyperthermiaincancerpatients-Therapeuticandimmunologicalstudies

PI: A.J.Neville,M.D. Projectperiod: 1986-1988 TotalDirectCosts: $219,900.00

Organization: MedicalResearchCouncilProjecttitle: ImmunoregulatoryepidermalfactorsPI: D.N.Sauder,M.D.Projectperiod: 1987-1989 TotalDirectCosts: $111,593.00

Organization: MinistryofHealth-CareerScientistAwardProjecttitle: ImmunoregulatoryepidermalfactorsPI: D.N.Sauder,M.D.Projectperiod: 1982-1992 TotalDirectCosts: $600,000.00

Organization: DermatologyFoundationProjecttitle: TheroleofIL-6inpemphigusvulgarisPI: J.McLean,M.D.Projectperiod: 1989-1990 TotalDirectCosts: $10,000.00


Projecttitle: StudiesonthemechanismofUV-inducedexacerbationsoflupuserythematosus

PI: D.N.Sauder,M.D. Projectperiod: 1988 TotalDirectCosts: $14,700.00


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Organization: BickellFoundationProjecttitle: MolecularcloningofepidermalcytokinesPI: D.N.Sauder,M.D.,

Projectperiod: 1988 TotalDirectCosts: $24,661.00

Organization: LupusSocietyofHamilton

Projecttitle: StudiesonthemechanismsofUV-inducedexacerbationsoflupuserythematosus

PI: D.N.Sauder,M.D. Projectperiod: 1988-1989 TotalDirectCosts: $10,000.00

Organization: MedicalResearchCouncilProjecttitle: EquipmentforstudiesofimmunologyandhostresistancePI: D.A.Clark,M.D.Projectperiod: 1987-1988 TotalDirectCosts: $87,000.00

Organization: Physicians'ServicesInc.Projecttitle: WholebodyhyperthermiaasamodulatoroftheimmunesystemPI: D.N.SauderProjectperiod: 1987-1988 TotalDirectCosts: $27,250.00

Organization: Physicians'ServicesInc.Projecttitle: RoleofcytokineinsystemicsclerosisPI: D.N.Sauder,M.D.Projectperiod: 1988 TotalDirectCosts: $65,000.00

Organization: Physicians'ServicesInc.Projecttitle: InsitudetectionofIL-1mRNAincutaneousTcelllymphomaPI: D.N.Sauder,M.D.Projectperiod: 1988-1989 TotalDirectCosts: $70,024.00Organization: UniversityofTorontoProjecttitle: MolecularcloningandexpressionofuniqueepidermalcytokinesPI: D.N.SauderProjectperiod 1988 TotalDirectCosts: $15,000.00


Page50of63

Organization: Chedoke-McMasterHospitalsFoundation Projecttitle: Astudyintothecytokineprofilesofepidermal

tissuefromT-celllymphomapatientsandfactorscontributingtoepidermalT-cellinfiltration

PI: R.C.McKenzie,PhD.Projectperiod: 1988-1989 TotalDirectCosts: $20,680.00

Organization: SquibbCanadaProjecttitle: DiversityandregulationofagerelatedchangesPI B.Cinader,M.D.Projectperiod: 1989-1991 TotalDirectCosts: $79,887.00

Organization: HealthandWelfareCanada

Projecttitle: Useofhumankeratinocytesinirritancyassaysforindustrialchemicals


Organization: JohnsHopkinsUniversity,CAAT

Projecttitle: Molecularcharacterizationofepidermalcytokines-apotentialinvitroassayforcontactdermatitis

PI: D.N.Sauder,M.D. Projectperiod: 1989-1990 TotalDirectCosts: $20,000.00

Organization: SandozCanadaInc.Projecttitle: MechanismofactionofcyclosporineAinpsoriasisPI: R.C.McKenzie,PhD.


Organization: HealthandWelfareCanada Projecttitle: InvivoandInvitrodermalabsorptionoffour

chlorinatedhydrocarbonsProjectperiod: 1991-1992 TotalDirectCosts: $53,500.00

Organization: HealthandWelfareCanada

Projecttitle: Invitroandinvivopercutaneousabsorptionofdrugsandenvironmentalchemicals


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PI: D.N.Sauder,M.D.Projectperiod: 1991-1992 TotalDirectCosts: $40,000.00Organization: MedicalResearchCouncilProjecttitle: ImmunoregulatoryepidermalcytokinesPI: D.N.Sauder,M.D.Projectperiod: 1992-1996 TotalDirectCosts: $250,352.00

Organization: MedicalResearchofCanada Projecttitle: UltrasoundbackscattermicroscopeforsuperficialskinimagingPI: F.S.Foster,M.D.


Organization: MedicalResearchofCanada Projecttitle: UltrasoundbackscattermicroscopeforsuperficialskinimagingPI: F.S.Foster,M.D.Projectperiod: 1995-1998 TotalDirectCosts: $128,945.00Organization: MedicalResearchCouncilProjecttitle: ImmunoregulatoryepidermalcytokinesininflammationPI: D.N.Sauder,M.D.Projectperiod: 1996-1998 TotalDirectCosts: $205,320.00

Organization: UnileverResearchU.S.Projecttitle: HighfrequencyultrasoundassessmentofskinelasticityPI: D.N.Sauder,M.D.Projectperiod: 1995-1996 TotalDirectCosts: $132,340.00

Organization: LeverBrothersProjecttitle: InvitrosurfactantpenetrationstudythroughhumanskinPI: D.N.Sauder,M.D.Projectperiod: 1995-1996 TotalDirectCosts: $81,000.00

Organization: HyalPharmaceuticalsProjecttitle: RegulatoryeffectofhyaluranicacidinskininflammationPI: D.N.Sauder,M.D.Projectperiod: 1996


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TotalDirectCosts: $30,000.00Organization: AeternaLesLaboratoriesProjecttitle: EffectofantiangiogenesisagentoncontactdermatitisPI: D.N.Sauder,M.D.Projectperiod: 1996 TotalDirectCosts: $25,000.00

D. CLINICAL TRIALS

EMLAtrialfordebridementofvenousandArteriallegulcers.(Co-investigator)

AstraPharma 1990-91

Double-blindrandomizedplacebo-controlledtrialofEMLAcreamforanalgesiapriortotreatmentofwartbycryotherapy(Co-investigator)

AstraPharmaInc. 1990-93

Arandomizeddouble-blind,placebocontrolledtrialoftheefficacy,safetyandtolerabilityoforalterbinafineinthetreatmentoftineapedisofthemoccasintype.(Co-investigator)

SandozCanadaInc. 1990-92

Comparativeeffectsofcalcipotriol(MC903)ointmentwithDithranolcream(shortcontact)inpsoriasisvulgaris.(Co-investigator)

LeoLaboratories 1990-92

Double-blindcomparativestudyofprednicarbate(Dermatop)emollientcream0.1%vsbetamethasonevaleratecream0.1%insubjectswithatopicdermatitis.

(Principalinvestigator)

HoechstCanadaInc. 1991-92

SafetyandefficacyofOcclucortlotion0.05%andDiprisone(betamethasonediproprionate)lotioninthetreatmentofhanddermatitis.(Principalinvestigator)

GenDerm 1991–92

EvaluationoftheclinicalefficacyandsafetyofKetoconazole2%emulsioninthetreatmentoftinea

cruris(Co-investigator).

JanssenPharmaceutica

1991–93

AphaseIVlong-termsafetystudyofmetronidazole(Metrogel)gel0.75%inacnerosacea.(Co-investigator).

LederleLaboratories 1992-94

Doubleblindclinicalsafetyandefficacyevaluationof Owen/Galderma 1991-92


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CD2710.1%creamvs.placebo.(Co-investigator).

Amulti-centre,double-blind,placebo-controlledcomparativeevaluationof12weeksand24weeks

treatmentwithterbinafine(250mgdaily)vs.placebointhetreatmentofonychomycosisofthetoenails.(Co-investigator)

SandozCanada 1992-93

EfficacyandsafetyofcalcipotriolcreamIIintreatmentofscalppsoriasis(doseranging)(Principalinvestigator)


DuoDermEvs.Salinedressingsinthetreatmentoflegulcers:Astudyoncosteffectiveness(Co-investigator)

Convatec-Squibb 1993–94

Theregenerationofstratumcorneumaftertape-stripping.(Co-investigator)

MediPro 1993

Single-blind,multicentrestudycomparingSCH471ointmentdailytoDiprosalicointmentb.i.d.inthe

treatmentofpsoriasis(Principalinvestigator)

ScheringCanada 1993-94

EfficacyandsafetyofcalcipotriolcreamIIintreatingpsoriasisvulgarisoftheface(Principalinvestigator)

LeoLaboratories 1993

Evaluationoftheclinicalefficacyandsafetyoforalitraconazoleinthetreatmentoftineapedis

(Co-investigator)

JanssenPharmaceutica

1994-96

SurveillanceofSafetyandEffectofSandimmuneintheTreatmentofSeverePsoriasis(Principalinvestigator)

Sandoz 1993

Vehiclecontrolledsafety:efficacytrialevaluation5%imiquimodcreamforthetreatmentofgenital/perianalwartsinmen(Principalinvestigator)

3MPharmaceuticals 1993-94

Lowenergylasertherapyinthetreatmentoflegulcers(Principalinvestigator)

InternationalMedicalInstrumentsInc.

1993-96

Comparativeeffectsoffusidicacid(2%)anderythromycin(2%)solutioninthetreatmentofacnevulgaris(Co-investigator)


Evaluationoftheclinicalefficacyandsafetyoforal Janssen 1994-95


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itraconazolepulsetherapyinthetreatmentofonychomycosisofthetoenail(Co-investigator)

Pharmaceutica

Astudytocomparequalityoflifeinpatientstreatedwithsuppressiveacyclovirtherapyvsthosetreatedwithacuteoralacyclovirtherapyinthemanagementofrecurrentgenitalherpes(Principalinvestigator).

BurroughsWellcome1994-96

Adouble-blind,parallelgroupcomparisonoftheefficacyandsafetyofBMS191158/1881159solution(2%4-hydroxyanisole/0.01%tretinoin)vs.individualactiveagentsandvehicleinthetreatmentofsolarlentiginesandrelatedhyperpigmentedlesions.(Co-investigator)

Bristol-MyersSquibb1994-95

Acomparativestudyoftheatrophogenicpotential,efficacyandsafetyof1)calcipotriolointmentbid2)betamethasone17-valerateointmentbid3)clobetasol17-propionateointment4)vehicleofointmentbidinthetreatmentofpsoriasisvulgaris(Principalinvestigator)


Adouble-blindrandomized,vehicle-controlled,parallel-group,multicentrestudyassessingthesafety,efficacyandsubjectacceptanceofsodiumsulfacetamide10%andsulfur5%inthetreatmentofrosacea.(Principalinvestigator)

GenDerm 1995-97

Aprotocoltoassessthesafetyandefficacyofclindamycinphosphatecream(=to1%clindamycin)withsunscreencomparedphosphatetopicalsolution(Principalinvestigator)

Stieffel 1995

Adouble-blind,placebo-controlledstudytoinvestigateherbalextractinandrogenicalopecia(Principalinvestigator)

Steff 1994-97

Arandomized,double-blind,parallelgroupstudyoftheefficacyandthesafetyofanemollientformulationofammoniumlactate12%and30%creamsvs.theirvehicleinthetreatmentofsignsassociatedwithphotodamage.(Principalinvestigator)

BristolMyersSquibb 1995

Adouble-blind,multinationaltrialcomparingsorivudinevsacyclovirforthetreatmentofacute

BristolMyersSquibb 1995


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localizedzosterandtheeffectonzosterassociatedpaininimmunocompetentsubjects(Co-investigator)

Amulticentre,double-blind,placebo-controlled,randomizedstudytoevaluatethesafetyandefficacyoftopical3%diclofenacin2.5%hyaluronangelinthetreatmentofoutpatientswithactinickeratosis(Co-investigator)

HyalPharmaceuticals 1995

AoneyearopenstudyinvestigatingthesafetyandefficacyofshortcoursesofSandimmuneNeoraltomanagepatientswithchronicplaquepsoriasisinadequatelycontrolledwithtopicaltherapies(Principalinvestigator)

Sandoz 1995

AmulticenterPhaseIIIblinded,randomizeddouble-blindplacebocontrolledstudytoevaluatetheefficacyoftwodoselevelsofDAB389IL-2(9and18ìg/kg/day)incutaneousT-celllymphoma(CTCL)patientswithstageIa-IIIdiseasewho,following>3previoustherapiesorstageIVadiseasepatientsfollowing1previoustherapies,haverecurrentorpersistentdisease(Prinicipalinvestigator)

Seragen 1995–96

TheSafetyofSandimmuneNeoral(CyclosporinA,Cyclosporine)intheTreatmentofPatientswithSevere,RefractoryAutoimmuneDisease:ACompassionateNeedStudyProgram-NEO-CDN-12.(PrincipalInvestigator)

Sandoz 1996

Asinglecentre,prospective,randomized,double-blindwithin-subjectcomparativestudyoftheatrophogenicpotentialof1)CalcipotriolOintment2)Bethamethasone17-ValerateOintment3)MometasoneFuroateOintment4)VehicleofCalcipotriolOintmentinhealthyvolunteers-MCO9407.(PrincipalInvestigator)


Asingle-centre,double-blind,randomizedplacebostudyevaluatingthesafetyandefficacyoforalAE-941versusplacebo(non-activeingredient)inmildtomoderateplaquepsoriasis.(PrincipalInvestigator)

AeternaLaboratories 1996

A48-HourPatchTestwithSOLARASEJ(3%diclofenactopicalgel-CT1101),anddiclofenacinpetrolatum

HyalPharmaceuticals 1996


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baseandethanolbaseinpatientspreviouslyexposedtoCT1101todeterminetheincidenceoflocalorsystemicsensitization/irritationreactions-CT-1101-08.(Co-investigator)

Arandomizeddouble-blind,placebo-controlled,multicentrestudyoftheefficacyandsafetyofLamisil(terbinafine)250mgtabletdailycomparedtoplaceboforoneweekinsubjectswithmultipleskininfections(atleasttwosites)-LAS-CDN-05.(Co-investigator)

Novartis 1996

AComparativePhaseIIIClinicalTrialwithTacrolimus(FK506)OintmentinPediatricPatientswithAtopicDermatitis.(PrincipalInvestigator).

Fujisawa 1997-98

AnOpen-LabelStudytoEvaluatetheSafetyandEfficacyoftheProforeFourLayerBandageSysteminPatientswithVenousLegUlceration.(PrincipalInvestigator).

Smith-Nephew 1997

AnOpen-Label,MulticentreSafetyandEfficacyStudyof5%TopicalImiquimodCreamintheTreatmentofVisible,ExternalGenital/PerianalWartsinMaleandFemalePatients-1243-IMIQ.(Co-Investigator)

3MPharmaceuticals 1997

AComparisonofOralValtrex500mgTwiceDailyforThreeorFiveDaysforTreatmentofRecurrentGenitalHerpes-550/070.(Co-investigator)

Novartis 1997

AParallelArmDouble-Blind,Placebo-Controlled,EfficacyStudyofAmmoniumLactateLotion(12%)andLac-Hydrin®inPatientsWithModerateorGreaterIchthyosisVulgaris(PrincipalInvestigator)

Paddock 1998

ADoubleBlind,ControlledStudyComparingtheEffectofAlphaHydroxyAcid(8%glycolicacid)/Retinol0.1%MoisturizertoanEmollient/HumectantMoisturizeronSkinElasticity.(PrincipalInvestigator)

Unilever 1998

ADoubleBlindPlaceboControlledMulticentrePhaseIIStudytoAssesstheSafetyBiologicalActivityandEfficacyofhu1124inPatientswithModeratetoSeverePlaquePsoriasis.(Co-investigator)

XOMACorp 1998-99

Anopen-labeltrialtoevaluatethesafetyandefficacy Allergan 1998-99


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ofTazorac®0.1%Gel(QD)usedinconjunctionwithElocom®0.1%Cream(QD),comparedwithElocom®0.1%Cream(QD)usedalone,intreatingsubjectswithmildtomoderateplaquepsoriasisforupto12weeksfollowedbyanotreatmentphase.(PrincipalInvestigator)

Phase2-3EvaluationofTargretinÔCapsulesinPatientswithRefractoryAdvancedCutaneousT-CellLymphoma(MycosisFungoides)-L1069-24;Phase3EvaluationofTargretin®TopicalGelinRefractoryorPersistentEarlyStageCutaneousT-CellLymphoma(MycosisFungoides)(PrincipalInvestigator)

LigandPharm 1998-99

ApligrafÔ:ACanadianPost-MarketingSurveillanceProgram.(Co-investigator)

Novartis 1998-00

Open,randomized,positivecontrol,multicentrestudyontheefficacyandcosteffectivenessofApligrafÔinvenousstasisulcersubjectswithsuboptimalhealingafter4weeksofhighcompressiontherapy.(PrincipalInvestigator)

Novartis 1998-00

Amulticentre,parallelgroup,double-blind,activecontrolledstudytoevaluatethelong-termsafetyandefficacyofSDZASM981Creamappliedtwicedailyforupto12monthsinsubjectswithatopicdermatitis.(Co-investigator)

Novartis 1998-00

OpenLabelLong-TermFollow-upStudyofTopicallyAppliedTacrolimusOintmentfortheTreatmentofAtopicDermatitisinPediatricPatients.(PrincipalInvestigator)

Fujisawa 1999-00

PhaseI/IIstudyofthesafetyandefficacyofteapolyphenolsinthetreatmentofexternalgenitalwartsinmen.(PrincipalInvestigator)

Epitome 1999-00

Anopen-label,pilotstudyofVAS972therapytodeterminethesafetyandeffectivenessinpatientswithmoderatetoseverepsoriasis.(PrincipalInvestigator)

Vasogen 2000


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III. EDUCATIONAL ACTIVITIES

A. VISITING PROFESSOR LECUTRES, INVITED LECTURES AND PANELS • ChairandSpeaker,TorontoPost-GraduateSeminar“Angiogenesis-NewApproachesfor

Dermatology”September19-20,1997• Avon“MolecularBasicsofCutaneousInflammation”NewYorkStateJanuary15,1998• EasternWinterDermatologyConference“BiologicResponseModifiers-NewIncitesinthe

TreatmentofPapillomaVirus”“Angiogenesis-NewTargetsforDermatologicTherapies”Stowe,VermontJanuary24-28,1998

• WinterSkinSeminar“MechanismsofContactDemratitis:FromBenchtoBedsideandBack”• “Angiogenesis-NewTargetsforDermatologicTherapies”Snowmass,COJanuary31-

February5,1998• BiologicSciencesSeminar-UniversityofToronto“ImmunoFunctionsoftheSkin-Bullous

Diseases”Toronto,ONFebruary19,1998• DepartmentofLaboratoryMedicineandPathobiology,UniversityofTorontoGraduate

ImmunologyCourse“ImmunopathologyoftheSkin”Toronto,ONMarch12,1998• GrandRounds-Women’sCollegeHospitalToronto,ONMarch13,1998• EsteeLauder“Ultravioletlightinducedapoptosis”NewYorkMarch23,1998• 3MPharmaceuticals-ImmiquimodMeeting“ImmunologyofImmiquimod”Toronto,ON

April4&5,1998• Unilever“ModulationofCytokines:MolecularMechanismsofIrritation”NewYorkCityApril

29,1998• CanadianDermatologyAssociationChair&Speaker“NewDirectionsintheTreatmentof

PapillomaVirus”July4th,1998• GrandRounds-Women’sCollegeHospital“NovelImmunoTherapies-SDZ981" August

7th,1998• 2ndAnnualInternationalPsoriasisSymposium“Angiogenesisantagonistsastreatmentfor

psoriasis:phase1clinicaltrialresultswithAE-941"September3rd,1998• TorontoPost-GraduateSeminar“NovelImmunoTherapies-SDZ981"“Molecular

MechanismsoftheCutaneousimmuneResponse-TargetsforNovelImmunotherapies”September18th-19th,1998

• “TheRoleoftheCellularImmuneSysteminthePathologyofPemphigusVulgarisAcantholysis”RoyalCollegeofPhysicians&SurgeonsSeptember26th,1998

• VisitingProfessor“MolecularMechanismsoftheCutaneousimmuneResponse-TargetsforNovelImmunotherapies”ColumbiaUniversity-NewYorkNovember17th&18th,1998

• VisitingProfessor“MolecularMechanismsoftheCutaneousimmuneResponse-TargetsforNovelImmunotherapies”UniversityofLouisville,KentuckyDecember1st

• KeynoteSpeakerSocietyofCosmeticChemists“MolecularMechanismsintheCutaneousInflammatoryResponse”NewYork,NYDecember10th&11th,1998

• PeerReviewPanelMemberCorrositexAnInVitroTestMethodforAssessingDermalCorrosivityPotentialofChemicalsWashington,DCJanuary21st-22nd,1999

• SpeakerEasternWinterDermatologyConference“MolecularMechanismsintheCutaneousInflammatoryResponse”Stowe,VermontJanuary23-27,1998


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• RecentAdvancesinClinicalImmunology-ImmunologyGraduateCourseIM1020S“ImmuneFunctionoftheskinandPathogenesisofAutoImmuneBullousSkinDiseases”Toronto,ONFebruary18,1999

• PanelMember-TheArthritisSocietyConsensusonHydroxychloroquinneLakeLouise,ABFebruary25-March1,1999

• SpeakerTorontoHospitalGrandRounds“MolecularMechanismsintheCutaneousInflammatoryResponse”April1,1999

• SocietyofInvestigativeDermatologyPosterPresentations“Il-10ImmunomodulationinTreatmentofPemphigus”-presentedMay7th,1999“RoleofFASAssociatedDeathDomainProteininUVBInducedApoptosis”-presentedMay8th,1999

• “ImpairedUltraviolet-BInducedCytokineInductioninXerodermaPigmentosumFibroblasts”-presentedMay8th,1999

• “Imiquimod,aTopicalImmuneResponseModifier,InducedMigrationofLangerhansCells”-presentedMay7th,1999

• “IL-1αandTNF-αarethemaincytokinesinvolvedinacantholysis”-presentedMay8th,1999• “CytokinePathwaysinContactHypersensitivity:roleofIL-10andIL-18"-presentedMay7th,

1999• SunnybrookMedicalGrandRounds“Angiogenesis”May11,1999• VisitingProfessor.“SkinImmuneSystemfromBenchtoBedsideandBack”EmoryUniversity

May12-13,1999• The1stMeetingoftheExperimentalContactDermatitisResearchGroup“InvolvementofIL-

18inInductionofContactHypersensitivity”Cincinnati,OHMay21st,1999• CDFLectureship“SkinImmuneSystemfromBenchtoBedsideandBack”Canadian

DermatologyFoundationMeetingJuly3rd,1999• CDAAbstractPresenter“AE-941,anInhibitorofAngiogenesis:PhaseIclinicaltrialresultsin

moderatetoseverepsoriasis”CanadianDermatologyFoundationJuly4th,1999• VisitingProfessor.UniversityofCalifornia,Davis“MolecularMechanismsofCutaneous

ImmuneResponse”July28th-30th,1999• VisitingProfessor.John’sHopkinsUniversity.“MolecularMechanismsofCutaneous

ImmuneResponse”July28th-30th,1999August25th-26th,1999• Co-Chair.6thInternationalWorkshoponLangerhansCells.October8th,1999• Presenter.6thInternationalWorkshoponLangerhansCells.“RoleofCytokinesinEpidermal

LangerhansCellMigration”October8th,1999• VisitingProfessor/InvitedLecturer.St.Peter’sUniversity,Newcastle,UK“Angiogenesis

AntagonistsasTreatmentforPsoriasis”November12th,1999• VisitingProfessor/InvitedLecturer.MonklandsHospital,Airdrie“AngiogneesisAntagonists

asTreatmentforPsoriasis”Novmeber15th,1999• VisitingProfessor/InvitedLecturer.St.Thomas’Hospital,London,England“Angiogenesis

AntagonistsasTreatmentforPsoriasis”November17th,1999• VisitingProfessor/InvitedLecturer.RoyalSocietyofMedicine,London,England.“Molecular

BasisofCutaneousImmuneResponse”November18th,1999• VisitingProfessor/InvitedLecturer.OxfordRadcliffeHospital.“MolecularBasisofCutaneous

ImmuneResponse”November19th,1999


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• InvitedLecturer.TheUniversityofVermont‘ManagementofthePatientwithPemphigus”January24,2000

• InvitedLecturer.TheUniversityofVermont“CreativeUsesofImiquimod”January25,2000• Lecturer.AmericanAcademyofDermatology“EpidermalCytokinesandtheirrolein

CutaneousBiologyandDisease”March10,2000• Lecturer.AmericanAcademyofDermatology.“ModulationofAngiogenesisinthe

TreatmentofPsoriasis”March12,2000• Lecturer.AmericanAcademyofDermatology.“TherapiestoControlAngiogenesis”March

14,2000• Chair,ScientificSessions.“What’sNewinBiologics”AtlanticDermatologicalSociety

Conference.April2002• RoyalCollegeVisitingProfessor.33rdAnnualScientificMeetingoftheAustralasianCollege

ofDermatologists.“PhotobiologyandPhototherapy”“TheSkinImmuneSystemfromBenchToBedsideandBack”“NewImmunosuppressiveAgents”“NovelTreatmentoftheHumanPapillomaVirus”May16thto24th,2000

• Lecturer.EasternWinterDermatologyConference.“Psoriasis:UpdateonPathogenesisandTreatment”“AlopeciaAreata”January19-23rd,2002

• Lecturer.AmericanAcademyofDermatology.“StructureandFunctionoftheSkin:EpidermalCytokines”February2002.

• BramRoseMemorialLecturer.CanadianSocietyforAllergyandClinicalImmunology.“UpdateofImmunologicTherapiesforSkinDisease”November10th,2002

• Lecturer.3MPharmaceuticalsInternationalRoundtableOnImmuneResponseModifiersinDermatology.“ModeofActionofImiquimod”November15th,2002

• Lecturer.DermatologyPathophysiologyCourse.“Pharmacology:ImmunomodulatorTherapyinSkinDisease”November26,2002

• Lecturer.EasternWinterDermatologyConference.“PsoriasisandtheNewBiologics”January18th–21st,2003

• Lecturer.20thColloquiumonClinicalDermatology.“Psoriasis:UpdateonPathogenesisandTreatment”“AlopeciaAreata:PathogenesisandTreatment”January30thto31st,2003

• Lecturer.AmeviveLectureSeries.“FirstBiologicTreatmentforModeratetoSevereChronicPlaquePsoriasis”March19th,2003

• Lecturer.AmericanAcademyofDermatology.“StructureandFunctionoftheSkin:EpidermalCytokines”March22,2003

• Chair.InternationalInvestigativeDermatology.“AdvancesinBiotherapy:ThePivotalRoleofTNFInhibitionisPsoriasis”May2,2003

• Lecturer.SeminarsinDermatology“EpidermalCytokinesandtheirroleinCutaneousBiologyandDisease”May2003

• Lecturer.FloridaSocietyofDermatology&DermatologicSurgery.“BiologicsforPsoriasis”June8th,2003

• Presenter.AmgenMeeting.“IntegratingBiologicAgentsintoCare:AFocusonCoverageandReimbursement”July15,2003

• GuestSpeaker.RaptivaRegionalAdvisoryBoardMeeting.“Biologics-DetailedOverviewofCurrentBiologicAgents”August23,2003


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• Lecturer.DermatologyCMEWorkshop.“Definitions,Diagnosis,andTheRoleofDermatologists”September9,2003

• GuestSpeaker.DoverCommunications.“IntegratingBiologicAgentsintoCare:AFocusonCoverageandReimbursement”September16,2003

• VisitingProfessor.NewYorkUniversityMedicalCenter.“TherapeuticVignettes”“ImmunePathogenesisofPsoriasis:RoleofBiologicTherapies”October10,2003

• VisitingProfessor.UniversityofSouthFloridaGrandRounds.“TherapeuticVignettes”“ImmunePathogenesisofPsoriasis:RoleofBiologicTherapies”.October14,2003

• GuestSpeaker.PennsylvaniaAcademyofDermatology.“PsoriasisandthenewBiologics”October24,2003.

• Lecturer.RaptivaAdvisoryBoardMeeting.“OverviewofPsoriasis&Discussion”November8,2003

• Moderator.AMultidisciplinaryApproachtoMelanoma.Baltimore,MarylandNovember11,2003

• Lecturer.LasVegasDermatologySeminar.“ImmunePathogenesisofPsoriasis:RoleofBiologicTherapies”November13-16,2003

• Lecturer.DermatologyPathophysiologyCourse.“ImmunomodulatorsinDermatology”November24,2003

• GuestSpeaker.SocietyofToxicology.“Molecularapproachestocontacthypersensitivity:Implicationsforinvitrosystems”December9,2003

• Lecturer.AmericanAcademyofDermatology.“StructureandFunctionoftheSkinCourse:EpidermalCytokines”February7,2004

• Lecturer.NewandPotentialApplicationsforTNFInhibitors,AbbottRepresentatives.“Psoriasis”February26,2004

• VisitingProfessor.BrownUniversity.“WhatisNewinDermatologicTherapeutics”“ImmunePathogenesisofPsoriasis:RoleofBiologicTherapies”April7-8,2004

• VisitngProfessor.ThomasJeffersonUniversity“WhatisNewinDermatologicTherapeutics”“ImmunePathogenesisofPsoriasis:RoleofBiologicTherapies”April20,2004

• Lecturer.AmgenSymposium.“TargetingCriticalPathwaysinPsoriasis:TCell”April29,2004

• Lecturer.TopicsinClinicalMedicine.“ImmunePathogenesisofPsoriasis:RoleofBiologicTherapies”May7,2004

• VisitingProfessor.AustralianSocietyforDermatologyResearch.“WhatisNewinDermatologicTherapeutics”“ImmunePathogenesisofPsoriasis:RoleofBiologicTherapies”May15to19,2004

• ProgramDirector.Post-GraduateSeminarsinDermatology“TheEmergingWorldofBiologics:TherapeuticInsights”.Baltimore,Maryland.June6,2004

• VisitingProfessor.GenentechLectures.“WhatisNewinDermatologicTherapeutics”“ImmunePathogenesisofPsoriasis:RoleofBiologicTherapies”June8-9,2004

• Lecturer.InternationalPsoriasisSymposium.“StumptheProfessor:NewBiologics”“OtherUsesofBiologics”June10-13,2004

• Lecturer.GenentechLectures.“ImmunePathogenesisofPsoriasis:RoleofBiologicTherapies”September8-9,2004


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• Lecturer.SocietyofCosmeticChemists.“BiologyoftheSkin”September23,2004• Lecturer.TheSocietyofInvestigativeDermatology:PharmaceuticsandPharmacology.

“ImmunePathogenesisofPsoriasis:RoleofBiologicTherapies”October13-15,2004• InvitedSpeaker,EasternWinterDermatologyConference.“ImmunePathogenesisof

Psoriasis:RoleofBiologicTherapies”Stowe,Vermont,January21,2005• InvitedSpeaker,EasternWinterDermatologyConference.“What’sNewinDermatology”

Stowe,Vermont,January,24,2005• Lecturer.AmericanAcademyofDermatology.“StructureandFunctionoftheSkinCourse:

EpidermalCytokines”February19,2005• VisitingProfessor.WashingtonHospitalGrandRounds.Washington,D.C.,“RoleofBiologic

TherapiesinPsoriasis”March3,2005• InternationalPsoriasisConferenceChicago,ILJune2005“UpdateonPsoriasis”• InvitedSpeaker,SocietyofInvestigativeDermatology,PharmacologyCourse.SanAntonio,

TXOct2005.“ImmunePathogenesisofPsoriasis”• InvitedSpeaker,EasternWinterDermatologyConferenceStowe,VermontJanuary2006

“ImmunePathogenesisofPsoriasis:RoleofBiologicTherapies”and“What’sNewinDermatology”

B. EDUCATIONAL MENTORING Postdoctoral & Research Fellows

Dr.SaulMarkman July 1984 - Oct. 1984Dr.KenLeeChoi Oct. 1984 - June 1985Dr.MartaKelly July 1985 - Dec. 1986Dr.VictorTron July 1986 - July 1988Dr.RoddieMcKenzie Aug. 1987 - Sept 1991Dr.ShigeyukiNozaki July 1988 - Jan. 1991Dr.RenataSlapsys Feb. 1989 - June 1989Dr.ClaudioFeliciani Nov. 1989 - Sept. 1991Dr.Y.H.Won Jan. l990 - July 1991Dr.JudyMcLeanWismer July 1989 - July 1990Dr.EvaNg May 1991 - May 1992Dr.Eui-SooPark Nov. 1991 - June 1992Dr.SaveriaPastore Mar. 1993 - Feb. 1994Dr.TakeshiKono May 1992 - May 1994Dr.SeijiKondo May 1992 -Nov. 1994Dr.HiroshiFujisawa June 1994 - Oct.1998Dr.BingheWang June 1994 - presentDr.LihuaZhuang Oct. 1996 - May1999Dr.PaolaToto Feb.1997 - May1998Dr.PaoloAmerio Apr. 1997 - May1998Dr.HirotakeSuzuki Apr. 1997 - Oct.1999Dr.ShiguraKawara Jan. 1999 - Sept.1999Dr.HideakiWatanabe - March2003Dr.AdamMamelak Sep. 2001- Jun.2004


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Dr.ClemensEsche Jan. 2003 - Jun.2004Dr.AnnaDeBenedetto Sep. 2003- present

Graduate Students

TraceyArsenault 1988 - 1990DavidWong Sept. 1986 - Aug. 1988KevinGalley Feb. 1991 - Oct. 1992OzgurHuner Sept. 1991 - July 1993DianePaglia Sept. 1992 - Jun. 1996BradfordHamilton July 1994 - Mar. 1996

Graduate Students' Supervisory Committee

Lu,Chao May 1991 - presentLiisaBayko Feb. 1995 - presentAudreyRobinson Sept. 1995 - presentGarySkarja Sept. 1995 - presentPetrocelli,Theresa Sept. 1995 - presentMassimi,Isabella Sept. 2000 - present

Msc Supervisor

BrandonHowell October1999- 2001Immunology 450 Supervisor:

EdwinFong January2000 - 2001

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