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#datasaveslives A dataset used for the study of Schizophrenia genetics Jo Knight (CHICAS) Medical School & Data Science Institute

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Page 1: Data bites

#datasaveslives

A dataset used for the study of Schizophrenia genetics

Jo Knight – (CHICAS) Medical School & Data Science Institute

Page 2: Data bites

#datasaveslives

Story Starts here…..

“On the basis of current empirical evidence and mostly consensual assessments of informed opinion, it appears that the historical candidate gene literature did not yield clear insights into the genetic basis of schizophrenia.”

Five genes (..) were rated as highly likely to be a genetic risk factor for schizophrenia (rating ≥4 on a 1–5 scale). With the exception of DRD2, none of the informed ratings ≥4 is supported by empirical results from the older SZGene or the newer PGC mega-analysis.

Page 3: Data bites

#datasaveslives

Began in 2007Now > 800 investigators from 38 countries. > 900,000 individuals currently in analysis. “The PGC is the largest consortium and the largest biological experiment in the history of psychiatry.”“The PGC is passionate about open, inclusive, participatory, and democratic science.”

“Purpose: Unite investigators around the world to conduct analyses of genome-wide genomic data for psychiatric disorders.”

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#datasaveslives

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#datasaveslives