date: may 20, 2019 personal information etty (tika ......may 20, 2019 · etty (tika) benveniste,...

Benveniste

Date: May 20, 2019 PERSONAL INFORMATION Etty (Tika) Benveniste, Ph.D. US Citizen RANK/TITLE Senior Vice Dean for Basic Sciences, School of Medicine (SOM) Associate Vice President for Medicine and Basic Sciences Professor, Department of Cell, Developmental and Integrative Biology Business Address: School of Medicine Dean’s Office, Faculty Office Tower (FOT) 1220 The University of Alabama at Birmingham Birmingham, Alabama 35294

Phone: (205) 934-7667 or 996-0818 E-mail: [email protected] HOSPITAL AND OTHER (NON ACADEMIC) APPOINTMENTS None EDUCATION California State University, Chico Chico, California B.A., Biological Sciences, 1974-1978 University of California, Los Angeles Los Angeles, California Ph.D., Immunology, 1979-1983 MILITARY SERVICE None LICENSURE None BOARD CERTIFICATION None POSTDOCTORAL TRAINING Postdoctoral Fellow University of California, Los Angeles Department of Neurology U.C.L.A. School of Medicine October 1983 - May 1986 NIH Postdoctoral Training Grant Tumor Immunology 1984 - 1985 Stipend Award to attend Cold Spring Harbor Course: Molecular Biology of the Nervous System July 30 - August 11, 1985 Basic Research Science Grant/Neuropsychiatric Institute University of California, Los Angeles 1984 -1985; 1985-1986 Individual NIH Postdoctoral Training Grant Behavior and Neurosciences Group, NINCD 1985 – 1986 Postdoctoral Fellowship Award National Multiple Sclerosis Society 1986 - 1987

Benveniste

ACADEMIC APPOINTMENTS Research Biologist National Institutes of Health, Bethesda, Maryland Metabolism Branch September 1978 - July 1979 Assistant Professor Department of Neurology University of Alabama at Birmingham July 1986 – October 1988 Member, Graduate Faculty University of Alabama at Birmingham 1987 - present Assistant Professor Departments of Neurology and Cell Biology University of Alabama at Birmingham October 1988 - May 1992 Associate Professor, Tenured Department of Cell Biology University of Alabama at Birmingham June 1992-1995 Professor Departments of Cell Biology, Physiology and Biophysics, Neurology, and Neurobiology University of Alabama at Birmingham 1995- Director, Graduate Program Department of Cell Biology University of Alabama at Birmingham 1995-2000 Vice-Chairman Department of Cell Biology University of Alabama at Birmingham 1997-2000 Founding Associate Dean for Postdoctoral Education Graduate School University of Alabama at Birmingham 1999-2001 Chair, Department of Cell Biology University of Alabama at Birmingham November 2000-December 2011 Co-Director, HHMI Med-Grad Fellowship Program University of Alabama at Birmingham May 2006-2010 Associate Director, Basic Sciences Comprehensive Cancer Center University of Alabama at Birmingham September 2006- Co-Director, Cancer Cell Biology Program Comprehensive Cancer Center University of Alabama at Birmingham February 2007-March 2011

Benveniste

Alma B. Maxwell UAHSF Endowed Chair University of Alabama at Birmingham 2008-2015 Founding Chair, Department of Cell, Developmental and Integrative Biology University of Alabama at Birmingham February 2012-December 2015 Interim Senior Associate Dean for Research Administration and Development University of Alabama at Birmingham School of Medicine December 2014-September 2015 Co-Director, UAB Multiple Sclerosis Center University of Alabama at Birmingham November 2015- Senior Associate Dean for Research Administration University of Alabama at Birmingham School of Medicine September 2015-September 2018 Charlene A. Jones Endowed Chair in Neuroimmunology University of Alabama at Birmingham January 2016- Associate Vice President for Medicine and Basic Sciences April 2017- Senior Vice Dean for Basic Sciences University of Alabama at Birmingham School of Medicine September 2018- PROFESSIONAL SOCIETIES: American Association for University Women, 1985- American Association for the Advancement of Science, 1985- New York Academy of Sciences, 1986- International Society of Neuroimmunology, 1988- Elected to the International Advisory Committee of the International Society of Neuroimmunology, 1995- American Society for Neurochemistry, 1989- Member: Marian Kies Award Committee, American Society for Neurochemistry, 2004 – 2007 Member: Program Committee for 2005 – 2006 Meetings of the American Society for Neurochemistry, 2004 - 2006 ASN Council Member: 2007-2011 Member: Program Committee for 2010, ASN Meeting, 2009- Clinical Immunology Society, 1989- Member: Membership Committee, 1999- Member: Publications Committee, 1999- Chair, Publications Committee, 2000- American Association of Immunologists, 1990- Member: AAI Status of Women Council, 1999-2002 American Society for Microbiology, 1993- Association of American Medical Colleges: Graduate Research, Education and Training (GREAT), 1999- Society for Neuroscience, 2000- International Society for NeuroImmunomodulation, 2000- American Association of Anatomists, 2001- American Society of Cell Biology, 2001- Association of Anatomy, Cell Biology, Neurobiology Chairpersons, 2001- 2015 American Society for Biochemistry and Molecular Biology, 2003- Society for Neuro-Oncology, 2006- Society for Interferon Research, 2006- President-Elect: American Society of Neurochemistry, 2011- 2013 President: American Society of Neurochemistry, 2013- 2015 Past-President: American Society of Neurochemistry, 2015- 2017 Member: Abstract Review Committee, Society of Neuro-Oncology, 2015, 2016, 2017, 2018 Member: Program Committee for American Society for Neurochemistry, 2015- Member: Council of Faculty and Academic Societies, Association of American Medical Colleges, 2013- Member: Council of Faculty and Academic Societies, Administrative Council, 2013-2017 Member: AAMC Distinguished Research Award Selection Committee, 2014, 2015

Benveniste

Member: Americas Committee for Treatment and Research in Multiple Sclerosis (ACTRIMS) Program Committee Advisory Board, 2017- Member: Program Committee for Council for Faculty and Academic Societies, AAMC, 2017- Member: Group on Research Advancement and Development (GRAND) Steering Committee, AAMC, 2018- Member: Group on Research Advancement and Development (GRAND) Program Committee, AAMC, 2018- Member: Planning Committee for the AAMC-Experienced Leaders Workshop, 2018- Member: Abstract Selection Committee, ACTRIMS, 2018 Member: Program Committee, 3rd America’s School of Neuroimmunology (ASNI), 2018 - JOURNAL RESPONSIBILITIES: Editorial Boards: Journal of Neuroimmunology, 1991-2006 Developmental Neuroscience, 1993-2006 Associate Editor: Journal of Immunology, 1994-1995 Section Editor: Journal of Immunology, 1995-1999 GLIA, 1996-2006 Journal of Neuroscience, 2001-2007 Stroke, 2001-2004 Journal of Biological Chemistry, 2003-2008 Journal of Neurovirology, 2004-2012 Journal of Neuroinflammation, 2005- Journal of Neuroimmune Pharmacology, 2009- ASN Neuro, 2009- Journal of Interferon and Cytokine Research (JICR), 2014-2016 Reviewing Editor, E-Life, 2016 AD HOC REVIEWER FOR THE FOLLOWING JOURNALS: Journal of Cellular Physiology Journal of Neuropathology and Experimental Neurology Gene Brain Research American Journal of Physiology: Cell Physiology Infection and Immunity Cancer Research Proceedings National Academy of Science, USA Oncogene Annals of Neurology FASEB Journal Neuroscience Letters Journal of Leukocyte Biology Journal of Clinical Investigation Journal of Immunology Molecular Immunology Nature Medicine Journal of Virology Journal of Neuro-Oncology Journal of Neuroscience Journal of Neurovirology American Journal of Pathology Nature Neuroscience BLOOD PLoS One Science Signaling Neuro-Oncology Clinical Cancer Research GLIA Oncotarget Multiple Sclerosis Journal Scientific Reports PEER REVIEW PANELS: NIH Site Visit: AIDS Dementia Complex Program Project, 1988 Ad Hoc Reviewer: National Science Foundation, 1988, 1990, 1992

Benveniste

Member: Special Section for AIDS Dementia Complex Grants, NIH, 1988 Member: Special Section for AIDS and Related Research Review Group, NIH, 1988-1991 Ad Hoc Reviewer: National Multiple Sclerosis Society, 1989-Present NIH Site Visit: AIDS Dementia Complex Program Project, 1989 Consultant: Veterans Administration Research Proposals, 1989-present Member: Special Section for AIDS and Related Research Review Group (Neurology), NIH, 1990 NIH Site Visit: Neurological Disorders Program Projects, 1990 NIH Site Visit: Center for Demyelinating Diseases, 1991 Ad Hoc Member: Neurological Disorders Program Projects, Review Committee A, 1991 Ad Hoc Member: Experimental Immunology Section, 1992 Member: American Cancer Society: Advisory Committee for Cell Biology, 1992-1995 NIH Site Visit: Demyelinating Diseases Program Project, 1992 Ad Hoc Reviewer: Spinal Cord Research Foundation, 1992 - present Ad Hoc Reviewer: Wellcome Trust, 1993, 1994, 1998 Ad Hoc Reviewer: NIMH, NIA, 1993, 1994 NIH Site Visit: AIDS Dementia Complex Program Project, 1993 Member: NIH Study Section, Neurosciences Program Project Review Committee B, 1993 - 1997 Chairman: NIH Study Section, Neurosciences Program Project Review Committee B, 1995 - 1997 Chairman: Special NIMH Study Section, 1995 Reviewer: Human Frontier Science Program, 1996 Chairman: Special NINDS Study Section, 1997 Reviewer: Comitato Promotore Telethon, 1997 External Advisory Board: Center for Neurovirology and Neuro-degenerative Disorders, University of Nebraska Medical Center, 1997- Member: National Multiple Sclerosis Society Grant Review Committee, 1998 - 2003 Reviewer: Swiss National Science Foundation, 1998 Chairman: Special NINDS Study Section, 1998 Reviewer: DIR, NINDS, Board of Scientific Counselors, 1999 Member: NIH Study Section, Training Grant and Career Development Review Committee (NST), 1999 - 2002 Member: NIH Study Section, Clinical Neuroimmunology and Brain Tumors (CNBT), 2000 - 2004 Advisory Board: Sontag Foundation Scientific Advisory Board, 2003- Reviewer: DIR, NIMH, Board of Scientific Counselors, 2003 Member: National Multiple Sclerosis Society, Research Programs Advisory Committee (RPAC), 2004 - 2010 Chairman: NIH Study Section, Clinical Neuroimmunology and Brain Tumors (CNBT), 2004 - 2006 Member: Oklahoma Medical Research Foundation (OMRF) Board of Scientific Visitors, 2004 - 2010 Member: Medical Advisory Board, Southeastern Brain Tumor Foundation, 2005 - Member: Review Committee for the Department of Molecular, Cell and Developmental Biology, Mt. Sinai School of Medicine, 2005 Chair, External Advisory Board: Mayo Clinic Brain Tumor SPORE, 2007 – 2013 Ad Hoc Reviewer: NIH, 2007, 2008, 2009 Member: Abstract Review Committee, Society of Neuro-Oncology, 2007 Reviewer: DIRCR, NIH, Board of Scientific Counselors, 2007 Invited Reviewer: German Research Foundation, Transregional Collaborative Research Centers, 2007 Chair: NIH Study Section, Cellular and Molecular Biology of Glia, 2008-2010 Invited Reviewer: Science Foundation of Ireland, 2008 Member: External Advisory Board, MDACC Melanoma SPORE, 2008 - 2012 NIH Distinguished Editorial Board Member: Neurosciences, 2009 Chair, NMSS Task Force: Review of Pilot Research Award Program and Collaborative MS Research Center Award Program, 2009 Reviewer, DIR, NIMH: Board of Scientific Counselors, 2009 Chair, NeuroAIDS Think Tank Meeting: NINDS, 2009 Member: College of CSR Reviewers, 2010- Ad Hoc Reviewer: NMSS, 2010, 2012, 2016 Invited Reviewer: Science Foundation of Ireland, 2010 Invited Reviewer: New Zealand MS Society, 2010 Member: Center for Scientific Review (CSR) Advisory Council, 2011-2013 Invited Reviewer: German Research Foundation, Excellence Initiatives in The Life Sciences, 2012 Member: Barancik Prize for Innovation in Multiple Sclerosis Research Committee, 2013 Member: Progressive MS Alliance Basic Science Committee, 2014 Member: NMSS Collaborative Center Grants Review Committee, 2014 Reviewer: Michael J. Fox Foundation, 2015, 2016, 2017 Ad Hoc Reviewer: NIH Neurological Sciences and Disorders Committee C, 2015 Member: Barancik Prize for Innovation in Multiple Sclerosis Research Committee, 2015 Member: External Advisory Board, Winship Cancer Center, Emory University, 2015- Ad Hoc Reviewer: NIH Cancer Molecular Pathobiology (CAMP), 2016

Benveniste

Invited Reviewer: German Research Foundation, 2017 Ad Hoc Reviewer: NIH, Hypersensitivity, Autoimmune and Immune-mediated Disease (HAI), 2017 Reviewer: Michael J. Fox Foundation Inflammation Biomarkers RFA Initiative, 2017 Invited Reviewer: German Research Foundation, 2018 Reviewer: Michael J. Fox Foundation Inflammation Biomarkers RFA Initiative, 2018 Reviewer: Brain Tumor Funders Collaborative (BTFC) Advisory Panel Meeting, 2018 Reviewer: The Paul G. Allen Frontiers Group: 2018 Allen Distinguished Investigator Award Editor: NIH Transformative Research Awards, 2018 – 2019 Invited Reviewer: German Research Foundation, 2019 HONORS AND AWARDS: Fellow: American Association for the Advancement of Science, 2009 UAB Graduate School Dean’s Award for Excellence in Mentorship, 2014 National Multiple Sclerosis Society Volunteer Hall of Fame, Scientific Researcher, 2018 COMMITTEES: Coordinator: Neuroimmunology Seminar Series, 1986-1995 Member: Graduate Studies in Neuroscience, 1989- Member: Center for AIDS Research Program Development, 1989- Member: Graduate Studies in Cell Biology, 1990-2000 Curriculum Committee: Molecular Neuroimmunology Training Grant, 1990-1995 Chair: Cell Biology Seminar Series, 1991- 1995 Member: Admissions Committee for CMB, 1993 -1995 Member: Admissions Committee for Neuroscience Program, 1993-1997 Member: UAB Committee on Faculty Policies and Procedures, 1994-1995 Member: Tenure Definition Committee, 1994-1995 Member: Medical Education Committee - Assessment Subcommittee, 1995-1997 Member: Accelerated Fast Track Undergraduate Program, 1995- 2000 Member: External Advisory Committee; Department of Pathology, 1995-1997 Member: Graduate Council Advisory Committee, 1995-2000 Member: CMB Steering Committee, 1996- 2005 Member: UAB School of Medicine Research Advisory Committee (MED/RAC), 1996-2000 Member: Strategic Planning Committee - Inflammation, 1996-1997 Member: Neuroscience Curriculum Review Committee, 1997-1998 Chair: School of Medicine Space Planning Committee, 1997-1998 Senator: Faculty Senate, 1998-2000 Member: Child Health Research Center Advisory Committee, 1997- Member: Search Committee, Chair of Surgery, 1998-1999 Chair: Med-Rac Subcommittee on Space Planning, 2000-2001 Member: Distinguished Lecturer Nomination Committee, 2001 Member: Council for Postdoctoral Education (COPE), 2001-2003 Member: Search Committee, Chair of Neurology, 2001 Member: Breast SPORE Executive Committee, 2001-2010 Member: Research Advisory Group (RAG), 2002- 2010 Member: Brain Tumor SPORE Executive Committee, 2002- Member: Search Committee, Dean of Dentistry, 2003 Member: Search Committee, Dean of Medicine, Senior Vice-President for Medicine, 2003-2004 Member: Pancreatic SPORE Executive Committee, 2003- Member: SCCOR (Heart Failure) Executive Committee, 2004- Member: Search Committee, Chair of Psychiatry, 2004-2005 Member: Committee on Institutional Setting, 2004 Co-Chair: UAB Strategic Planning Initiative, 2005-2006 Member: Committee on Promotion and Tenure, 2005-2006 Co-Chair: Development and Aging Strategic Planning Group, 2005 Member: Bridge Funding Committee, 2005- 2010 Member: UAB Strategic Planning Implementation Committee, 2006- Chair: Strategic Implementation Subcommittee on Graduate Education, 2006-2008 Member: UAB Strategic Implementation Committee on IMPACT Funding, 2006- 2010 Member: Neuroscience Steering Committee, 2006- Member: Search Committee, Chair of Biology, 2006-2007 Member: 2007 CCC Retreat Program Committee, 2007 Member: Search Committee, Chair of Pharmacology, 2007

Benveniste

Co-Chair: Cancer Cell Biology Program Retreat, 2007 Member: Search Committee, Hem/Onc. Director 2008 Member: Faculty Incentive Committee, 2008-2009 Member: Search Committee, Dean of Medicine, Senior Vice-President for Medicine, 2009-2010 Member: SOM Space Committee, 2010- 2012 Member: Strategic Planning Committees for Immunology, Cancer Biology and Neuroscience, 2010- Member: Search Committee, Chair of Medicine, 2011- 2012 Member: GBS Steering and Oversight Committee, 2011- 2015 Faculty Advisor: SOM, Oncology Interest Group, 2011- 2015 Member: AMC21 Coordinating Council, 2011-2015 Member: GBS SOC Finance Subcommittee, 2012- 2015 Subcommittee Chair: LCME Faculty (FA) Subcommittee- Personnel Policies and Governance, 2012-2014 Member: LCME Steering Committee, 2012-2014 Member: Search Committee, Dean of Medicine, Senior Vice-President for Medicine, 2013 Member: AMC21 Executive Research Steering Committee, 2014-2015 Member: School-wide UWIRC Review, 2014 Member: Search Committee, Chair of Surgery, 2014-2015 Chair: Development of Master’s Degree in Biomedical and Health Sciences, 2014- 2015 Chair: Development of Cancer Biology Undergraduate Degree, 2014-2017 Chair: SOM Space Committee, 2015- Chair: Search Committee, Personalized Medicine Institute Director, 2016-2017 Member: Search Committee, Chair of Pathology, 2015-2016 Co-Chair: AMC21 Executive Research Steering Committee, 2015- Chair: SOM Bridge Funding, 2015- Chair: SOM IMPACT Awards, 2015- Member: Search Committee, Chair of Dermatology, 2015- 2016 Chair: SOM Executive Risk Oversight Committee, 2015- Chair: AMC21 Research Retreat, January 2016 Chair: SOM Master Space Planning Executive Committee, 2016- Member: Science and Technology Honors Program Leadership Council, 2016- Co-Chair: Search Committee, Director of the Comprehensive Cancer Center, 2016-2017 Member: Search Committee, Vice President for Research, 2016 Chair: Internal Advisory Board, UAB Women’s Reproductive Health Research (WRHR) Program, 2016- Chair: Oversight Committee for UABHA Center for Genomic Medicine, 2016- Chair: AMC21 Research Retreat on SOM Space, January 2017 Member: Search Committee, Chair of Neurobiology, 2017- Member: Internal Advisory Board, Institute for Cancer Outcomes and Survivorship, 2017- Member: Search Committee, Chair of Genetics, 2017- Chair: Oversight Committee for Kaul Precision Medicine Institute, 2017- Chair: SOM Recruitment Meetings, 2017- Chair: Comprehensive Cancer Center Advisory Committee, 2017- Member: Alabama Genomic Health Initiative (AGHI) Oversight Committee, 2017- Chair: AMC21 Research Retreat on Strategic Recruitment in the SOM, January 2018 Chair: SOM Master Space Plan Implementation Committee, 2018- Organizer: Inaugural SOM Research Roundtable, March 12-13, 2018 Organizer: UAB/SR Symposium on Precision Medicine, Neurosciences and Infectious Diseases, July 27, 2018 Chair: Search Committee, MSTP Director, 2018 Chair: SOM Strategic Recruitment in Cancer Initiative, 2018- Chair: SOM Strategic Recruitment in Neurosciences Initiative, 2018- Chair: SOM Strategic Recruitment in Outcomes and Health Disparities Initiative, 2018- Chair: AMC1 Research Retreat on Research Infrastructure in the SOM, January 2019 Co-Chair: Search Committee, Director of the O’Neal Comprehensive Cancer Center, 2019- Chair: SOM Initiative on Research Infrastructure-Core Facilities, 2019- INVITED PRESENTATIONS: Invited Speaker, Workshop on Functional Consequences of Demyelination: Effect of Cytokines on Glia La Sapinière, Val-David, Quebec, Canada June 1 - 5, 1988 Invited Speaker, National Cancer Institute, NIH: Effect of Cytokines on Astrocyte Gene Expression Bethesda, Maryland December 6, 1988 Invited Speaker, American Society for Neurochemistry Workshop on Neuroimmunomodulation: Regulation of Gene Expression in Astrocytes by Interferon-γ and Tumor Necrosis Factor-α

Benveniste

Chicago, Illinois March 4 - 6, 1989 Invited Speaker, Advances in Clinical Neuroimmunology: Basic Tenets of Immunology for Neuroimmunology University of Alabama at Birmingham, Birmingham, Alabama March 10, 1989 Invited Speaker, Workshop on the Role of Astrocytes in Inflammatory Demyelination: Inflammatory Mediators as Stimuli - Interleukins Galveston, Texas March 22 - 25, 1990 Invited Speaker, The Second Biennial Ray A. and Robert L. Kroc Symposium in Neurology: Cell Biology of the Oligodendrocyte University of Connecticut June 1, 1990 Invited Speaker, Workshop on Mechanisms of Vascular and Tissue Damage in Demyelinating Disease: Cytokine Action on Oligodendrocytes and Astrocytes San Martino al Cimino, Italy October 3 - 7, 1990 Invited Speaker, American Society for Neurochemistry Symposium: Signaling, Regulation and Gene Regulation in Astrocytes Charleston, South Carolina March 10-15, 1991 Invited Speaker, Ohio State University Cytokine Regulation of MHC Class II and Tumor Necrosis Factor Gene Expression in Brain Cells Columbus, Ohio May 28, 1991 Invited Speaker, Workshop on Neuro-AIDS: Drug Discovery and Development, Organized by NIAID and DAIDS, NIH Portland, Maine July 22-25, 1991 Invited Speaker, Marine Biological Laboratory Course: Pathogenesis of Neuroimmunologic Diseases Woods Hole, Massachusetts August 18-30, 1991 Invited Speaker, University of North Carolina Cytokine Regulation of Astrocyte Gene Expression and Function Chapel Hill, North Carolina September 19, 1991 Invited Speaker, Case Western Reserve University Class II MHC Gene Expression in Brain Cells: Involvement of Intracellular Signaling Pathways and Novel Nuclear Factors Cleveland, Ohio November 18, 1991 Invited Speaker, Workshop on Neurological Consequences of Immune Dysregulation: Lessons from HIV infection and Multiple Sclerosis: Cytokine Involvement in HIV/MS Sanibel Island, Florida January 18-21, 1992 Invited Speaker, Altschul Symposia on Biology and Pathology of Astrocyte - Neuron Interaction: Neuroimmune Network - Cytokines University of Saskatchewan, Saskatoon May 20-24, 1992 Invited Speaker, Workshop on CNS, Immune, Endocrine and Viral Interactions, Organized by NIMH, NIH Rockville, MD July 27-29, 1992

Benveniste

Invited Speaker, Association for Research in Nervous and Mental Diseases (ARNMD) Symposium on HIV, AIDS and the Brain: Cytokine Circuits in the Brain New York, New York December 3-4, 1992 Invited Speaker Emory University Graduate Student Association Invitation, Class II MHC Gene Expression in Glial Cells: Involvement of Multiple Signaling Pathways and Nuclear Factors Atlanta, Georgia April 14, 1993 Invited Speaker, American Association of Immunologists Minisymposium in Neuroimmunology: Intracellular Second Messengers Involved in Both Induction and Inhibition of TNF-α Expression by Astrocytes Denver, Colorado May 21-25, 1993 Invited Speaker, 3rd Workshop on Neuro-AIDS, Organized by NIAID and DAIDS, NIH Portland, Maine August 16-18, 1993 Invited Speaker, Marine Biological Laboratory Course: Pathogenesis of Neuroimmunologic Diseases Woods Hole, Massachusetts August 15-29, 1993 Invited Speaker, NMSS, Mid-South Chapter Annual Meeting, Memphis, Tennessee October 23, 1993 Invited Speaker, University of Iowa Cytokine Circuits in the Central Nervous System Cedar Rapids, Iowa November 16-17, 1993 Invited Speaker, Louisiana State University Cytokine Action on Glial Cells New Orleans, Louisiana March 24, 1994 Chair, Experimental Biology, 1994, APS Symposium, Cytokine Mediated Signal Transduction Pathways: Effects on Cellular Gene Expression and Function Anaheim, California April 24-29, 1994 Co-Chair, Experimental Biology, 1994, AAI Minisymposium, Immune Mechanisms in Demyelinating Diseases Anaheim, California April 24-29, 1994 Co-Chair, Experimental Biology, 1994, AAI Minisymposium, Immune Regulation and Soluble Mediators of CNS Inflammation Anaheim, California April 24-29, 1994 Invited Speaker, Cleveland Clinic Research Foundation Cytokine Regulation of Gene Expression in Glial Cells Cleveland, Ohio May 11-12, 1994 Invited Speaker, Berlex Biosciences Symposium on Multiple Sclerosis Richmond, California June 10, 1994 Invited Speaker, NMSS 1994 Southern Area Conference Charleston, South Carolina June 27, 1994 Chair, International Society for Developmental Neuroscience Symposium, Interactions Between the Immune and Nervous System

Benveniste

San Diego, California July 30-August 4, 1994 Invited Speaker, Neurocrine La Jolla, California July 31, 1994 Invited Speaker, NMSS, Setenga Chapter, Research Update on MS Chattanooga, Tennessee October 4, 1994 Plenary Lecturer, Cytokine Circuits in the CNS - Fourth International Congress of Neuroimmunology Amsterdam, The Netherlands October 23-27, 1994 Invited Speaker, University of Tennessee Memphis, Tennessee March 3, 1995 Invited Speaker, University of Pennsylvania Philadelphia, Pennsylvania March 13-14, 1995 Invited Speaker, Specialty Laboratories Santa Monica, California July 20, 1995 Co-Chair, International Symposium on Clinical Immunology Neuroimmunology Symposium, Soluble Factors Regulating CNS Inflammation San Francisco, California July 21-23, 1995 Invited Speaker, Maine Biological Laboratory Course: Pathogenesis of Neuroimmunologic Disease Woods Hole, Massachusetts August 13-25, 1995 Plenary Lecturer, Impact of Glial Biology and Immunology on Multiple Sclerosis and Other Demyelinating Diseases UCLA Neurobiology of Disease Conference Los Angeles, California November 8-10, 1995 Invited Speaker, International Symposium on Pathophysiology of Astrocytes and Microglia: Focus on Multiple Sclerosis and HIV-related Brain Damage Rome, Italy November 29-December 2, 1995 Invited Speaker, University of Utah Salt Lake City, Utah April 22-24, 1996 Invited Speaker, Cytokines in the Brain: Neuropathological Aspects Saint-Jean de Luz April 26-28, 1996 Member, Scientific Committee Plenary Lecturer 6th International Congress on TNF and Related Cytokines Rhodes, Hellas May 8-12, 1996 Invited Speaker, Scripps Research Institute La Jolla, California May 21-23, 1996 Co-Chair, American Society for Investigative Pathology ASIP Symposium, Glial Cytokines New Orleans, Louisiana

Benveniste

June 6, 1996 Invited Speaker, NMSS, Birmingham Chapter Research Update on MS Birmingham, Alabama July 9, 1996 Invited Speaker, HIV in the Brain: Pathology and Neurobehavioral Consequences, OAR, NIMH Washington, D.C. September 4-6, 1996 Invited Speaker, Boehringer Ingelheim Pharmaceuticals Ridgefield, Connecticut October 28-29, 1996 Plenary Speaker, Cytokines in Diseases of the CNS 2nd DAAK/GAAC Meeting on Molecular Medicine Reinberg Castle, Tegernsee, Germany November 17-20, 1996 Invited Speaker, Vanderbilt University Nashville, Tennessee December 10-11, 1996 Invited Speaker, NIH Bethesda, MD January 14, 1997 Invited Speaker, LSU Shreveport Shreveport, LA April 15, 1997 Invited Speaker Northwestern University Graduate Student Association Invitation Chicago, IL April 29, 1997 Invited Speaker, The University of Texas Health Science Center at San Antonio San Antonio, TX May 29, 1997 Invited Speaker, Marine Biological Laboratory Course: Pathogenesis of Neuroimmunologic Disease Woods Hole, Massachusetts August 19-21, 1997 Invited Speaker, University of Pittsburgh Center for Neuroscience Retreat Oglebay Park, West Virginia September 5-7, 1997 Invited Speaker, The Miami Project to Cure Paralysis, University of Miami School of Medicine 12th Annual Visiting Professor Lectureship Series Miami, Florida September 30 - October 2, 1997 Invited Speaker, The University of Nebraska Medical Center Omaha, Nebraska October 21-22, 1997 Invited Speaker, Neuroscience Colloquium Humboldt University Hospital Berlin, Germany January 27-29, 1998 Invited Speaker, University of Colorado, Boulder Boulder, Colorado February 19-20, 1998

Benveniste

Invited Speaker, American Society for Neurochemistry Neuroinflammatory Symposium Denver, Colorado March 7-11, 1998 Invited Speaker, University of Alabama at Birmingham Career Development Workshop Birmingham, Alabama March 27-28, 1998 Chair, Experimental Biology, 1998, AAI Minisymposium, Macrophage Activation San Francisco, California April 18-22, 1998 Invited Speaker, Berlex Biosciences Richmond, California June 8, 1998 Invited Speaker, FASEB Summer Conference, Neural-Immune Interactions in Injury and Disease: Pathways to Therapy Wilsonville, Oregon July 12-17, 1998 Invited Speaker, University of Arkansas Arkansas Center for Neuroscience Distinguished Scientist Lecturer Little Rock, Arkansas September 17-18, 1998 Invited Speaker, Neuroimmunology Seminar Series University of Wuerzburg Wuerzburg, Germany October 6-7, 1998 Invited Speaker, Symposium on Brain Development and Function: From Basic Science to Clinical Application Heidelberg, Germany October 8-9, 1998 Invited Speaker, NINDS AIDS Program Panel Number Two; Neuronal Injury in HIV Infection Miami Beach, Florida February 4-6, 1999 Invited Speaker, Keystone Symposium on Infections of the Nervous System: Host - Pathogen Interactions/Effectors of Inflammation in the CNS Taos, New Mexico March 9-13, 1999 Invited Speaker, University of Arkansas School of Medicine Little Rock, Arkansas April 26-28, 1999 Invited Speaker, International Society Neurochemistry/European Society Neurochemistry Joint Meeting Berlin, Germany August 8-14, 1999 Invited Speaker, Marine Biological Laboratory Course: Pathogenesis of Neuroimmunologic Disease Woods Hole, Massachusetts August 15-27, 1999 Keynote Speaker, Great Lakes Glia Meeting Traverse City, Michigan September 25-28, 1999 Invited Speaker, 2nd Santa Fe Symposium, In Defense of the Brain: Current Concepts in the Pathogenesis of CNS Infections Santa Fe, New Mexico October 16-19, 1999

Benveniste

Invited Speaker, Birmingham Southern College Birmingham, Alabama November 16, 1999 Invited Speaker, Case Western Reserve University Cleveland, Ohio December 14, 1999 Invited Participant, Committee on Science, Engineering and Public Policy Workshop: Enhancing the Postdoctoral Experience Washington, D.C. December 21, 1999 Invited Speaker, Rutgers University Newark, New Jersey February 10-11, 2000 Invited Speaker, Case Western Reserve University Cleveland, Ohio February 15-16, 2000 Invited Participant, John D. & Catherine T. MacArthur Foundation Scientific Meeting Galveston, Texas March 16, 2000 Invited Speaker, NIH-Sponsored Workshop I. The Role of the Immune System in Spinal Cord Injury Bethesda, Maryland April 4-6, 2000 Invited Speaker, University of Wisconsin Madison, Wisconsin April 18-19, 2000 Chair, American Association of Immunologists/Clinical Immunology Society Symposium: Cytokine/Chemokine Regulation of Immune Responses in the Central Nervous System Seattle, Washington May 12-16, 2000 Chair, American Association of Immunologists/Clinical Immunology Society Chemokines and Receptors Symposium Seattle, Washington May 12-16, 2000 Invited Speaker, The Next Neuroscience Generation – Neuroimmunology Berlin, Germany May 22-23, 2000 Chair, FASEB Summer Conference, Neural-Immune Interactions in Injury and Disease Copper Mountain, Colorado June 18-22, 2000 Invited Speaker, Loyola University Medical Center Maywood, Illinois October 2-3, 2000 Keynote Speaker, 9th Annual Retreat of Tulane University: Interdisciplinary Program in Molecular and Cellular Biology Camp Tchefunctc, Louisiana October 20-22, 2000 Invited Speaker, National Neurotrauma Society Meeting New Orleans, Louisiana November 3-4, 2000 Invited Speaker, UNC Charlotte Charlotte, North Carolina

Benveniste

November 17, 2000 Invited Speaker, University of South Alabama Mobile, Alabama November 29-30, 2000 Invited Speaker, The University of Texas Health Science Center at San Antonio, San Antonio Texas December 11, 2000 Invited Speaker, Uniformed Services University Bethesda, Maryland December 18-19, 2000 Invited Speaker, Roswell Park Cancer Institute Buffalo, New York January 9-10, 2001 Invited Speaker, Emory University Atlanta, Georgia January 26, 2001 Invited Speaker, Class II MHC Gene Regulation and Biologic/Clinical Applications Kiawah Island, South Carolina March 22-25, 2001 Invited Speaker, Yale University New Haven, Connecticut May 23-24, 2001 Invited Speaker, Marine Biological Laboratory Course: Pathogenesis of Neuroimmunologic Disease Woods Hole, Massachusetts August 15-19, 2001 Invited Speaker/Chair, International Society of Neuroimmunology Edinburgh, Scotland September 4-7, 2001 Invited Speaker, UMDNJ Newark, New Jersey November 28, 2001 Invited Speaker, University of California, Irvine Irvine, California January 17-18, 2002 Invited Speaker/Chair, Keystone Symposium on Stroke – Molecular, Cellular, Pharmacological and Development of New Therapies: Inflammatory and Immune Cells and Mediators in Stroke Taos, New Mexico March 9-14, 2002 Invited Speaker, 23rd Princeton Conference San Diego, California March 21-23, 2002 Invited Speaker, University of Maryland at Baltimore Baltimore, Maryland April 18, 2002 Invited Speaker, Stanford University Stanford, California April 29-30, 2002 Plenary Speaker, 4th Annual International Symposium on Neurovirology Dusseldorf, Germany June 19-22, 2002

Benveniste

Invited Speaker, American Society for Neurochemistry Palm Beach, Florida June 22-26, 2002 Invited Speaker, University of Nebraska Omaha, Nebraska July 17-19, 2002 Chair, FASEB Summer Conference, Neural-Immune Interactions in Injury and Disease, Tucson, Arizona August 17-22, 2002 Invited Speaker, NIH Workshop on Astrocyte Function in Health and Disease Washington, D.C. September 23-25, 2002 Invited Speaker, Multiple Sclerosis Preceptorship Birmingham, Alabama October 5, 2002 Invited Speaker, NIH Rockville, Maryland October 23, 2002 Invited Speaker, New York Medical College Valhalla, New York November 6, 2002 Invited Speaker, SPORE Meeting UCSF San Francisco, California January 9-10, 2003 Invited Participant, VA-NINDS ALS Meeting Washington, D.C. January 21, 2003 Invited Speaker, 28th International Stroke Conference of the AHA/ASA Phoenix, Arizona February 13-15, 2003 Invited Speaker, University of New Mexico Albuquerque, New Mexico March 6, 2003 Invited Speaker, University of Nebraska, Lincoln Lincoln, Nebraska April 22, 2003 Invited Speaker/Chair, American Society of Neurochemistry Newport Beach, California May 3-8, 2003 Symposium Speaker, Oklahoma Center for Neuroscience The University of Oklahoma Oklahoma City, Oklahoma June 11-12, 2003 Invited Speaker, Kentucky Spinal Cord and Head Injury Research Trust Symposium Louisville, Kentucky June 27-28, 2003 Invited Speaker, Bioteach McWane Center Birmingham, Alabama

Benveniste

July 11, 2003 Invited Speaker, Marine Biological Laboratory Course: Pathogenesis of Neuroimmunologic Disease Woods Hole, Massachusetts August 13-15, 2003 Plenary Speaker, The 5th International Symposium on NeuroVirology Baltimore, Maryland September 4-6, 2003 Guest Lecturer, 7th Annual NIMH Scientific Retreat Gettysburg, Pennsylvania September 22-23, 2003 Invited Speaker, Alabama Chapter of the NMSS Annual Meeting Birmingham, Alabama October 10, 2003 Invited Speaker, University of Oklahoma Oklahoma City, Oklahoma November 13-14, 2003 Executive Chair/Speaker, NIH Workshop on Glial Inflammation in Chronic Neurodegenerative Diseases Washington, D.C. December 7-10, 2003 Invited Speaker, The 2004 Schmitt Symposium: Immune and Inflammatory Responses in the CNS Rochester, New York April 23, 2004

Invited Speaker, Midwest Inflammation Research Association Symposium on Neuroinflammation Indianapolis, Indiana May 2-3, 2004 Invited Speaker/Chair, FASEB Summer Conference Neural-Immune Interactions: Physiological and Pathological Relevance Tucson, Arizona August 7-12, 2004 Invited Chair, International Society for Neuroimmunology Venice, Italy September 28-October 2, 2004 Invited Symposium Speaker, Society for Neurosciences San Diego, California October 23-27, 2004 Invited Speaker, University of Calgary Calgary, Canada November 17-19, 2004 Invited Speaker, UT Southwestern Dallas, Texas December 13-14, 2004 Invited Speaker, Gordon Research Conference on Glial Biology Ventura, California March 13-18, 2005 Invited Speaker, University of Kentucky, Louisville Louisville, Kentucky May 19, 2005

Benveniste

Invited Speaker, Marine Biological Laboratory Course: Pathogenesis of Neuroimmunologic Disease Woods Hole, Massachusetts August 14-16, 2005 Invited Speaker, Seoul National University Seoul, S. Korea October 28, 2005 Symposium Speaker, The Korean Society for Brain and Neural Science Seoul, S. Korea October 28, 2005 Invited Speaker, Emory University Atlanta, Georgia November 8, 2005 Invited Speaker, SONTAG Brain Tumor Foundation Jacksonville, Florida March 8-10, 2006 Invited Speaker, American Society for Neurochemistry Portland, Oregon March 11-15, 2006 Invited Speaker, Mayo Clinic Rochester, Minnesota April 19-20, 2006 Invited Speaker, University of Michigan Ann Arbor, Michigan May 11-12, 2006 Invited Speaker, University of Illinois Peoria, Illinois May 25-26, 2006 Invited Speaker/Chair, FASEB Summer Conference Neural-Immune Interactions Tucson, Arizona August 5-10, 2006 Invited Speaker, Stony Brook Stony Brook, New York September 18-19, 2006 Invited Speaker, Baylor College of Medicine Houston, Texas October 11-12, 2006 Invited Speaker, Society for Neuro-oncology Orlando, Florida November 15-19, 2006 Invited Speaker, UNC Chapel Hill Chapel Hill, North Carolina November 29-30, 2006 Invited Chair, Gordon Conference on Glial Biology Ventura, California March 11-16, 2007 Invited Speaker, American Association of Immunologists Miami, Florida May 18-22, 2007

Benveniste

Guest Speaker, 2007 Aspen Symposium on Brain Tumor Immunotherapy Aspen, Colorado August 5-8, 2007 Invited Speaker, Marine Biological Laboratory Course: Pathogenesis of Neuroimmunologic Disease Woods Hole, Massachusetts August 20-21, 2007 Invited Speaker, The 2007 International Workshop on Glioma Research and Therapy Boston, Massachusetts October 10-13, 2007 Invited Speaker, American Society for Neurochemistry San Antonio, Texas March 1-5, 2008 Invited Speaker, Chair Seminar – Panel Discussion Birmingham, Alabama March 7, 2008 Invited Speaker, Mt. Sinai University New York, New York April 14-15, 2008 Invited Speaker, Johns Hopkins University Baltimore, Maryland May 14-15, 2008 Invited Speaker, FEBS Annual Meeting Athens, Greece June 28-July 3, 2008 Invited Chair/Speaker, FASEB Summer Conference Neural-Immune Interactions Carefree, Arizona August 3-8, 2008 Invited Speaker, University of Virginia Charlottesville, Virginia September 21-22, 2008 Invited Chair, International Society for Neuroimmunology Fort Worth, Texas October 26-30, 2008 Invited Speaker, Comprehensive Cancer Center Birmingham, Alabama November 3, 2008 Invited Speaker, Tykeson Fellows Conference on Multiple Sclerosis Chicago, Illinois November 4-7, 2008 Invited Speaker, Glial Biology in Medicine Symposium Birmingham, Alabama December 1-3, 2008 Invited Speaker, American Society for Neurochemistry Charleston, South Carolina March 7-11, 2009 Invited Speaker, 5th International Mickeln Symposium on Neurodegeneration and CNS Repair Dusseldorf, Germany May 13-17, 2009 Invited Speaker, Consortium of MS Centers

Benveniste

Atlanta, Georgia May 26-27, 2009 Invited Speaker, International Society of Neurochemistry Busan, South Korea August 23-28, 2009 Chair and Invited Speaker, NIH, NeuroAids Think Tank Meeting Rockville, Maryland November 2, 2009 Invited Speaker, Birmingham Southern College, Women In Science Panel Birmingham, Alabama November 12, 2009 Invited Speaker, Virginia Commonwealth University Richmond, Virginia February 22-23, 2010 Distinguished Lecturer, Georgia State University, Molecular Basis of Disease Area of Focus Atlanta, Georgia April 22, 2010 Invited Speaker, New York Academy of Sciences: Innate Inflammation as the Common Pathway of Risk Factors Leading to Transient Ischemic Attacks and Stroke New York, New York May 9-10, 2010 Invited Participant, SFB TRR43, International Symposium Berlin, Germany June 2-6, 2010 Invited Speaker, NIAID Immunology Workshop, Rocky Mountain Laboratories Hamilton, Montana August 5-6, 2010 Invited Symposium Speaker, International Society for Neuroimmunology Barcelona, Spain October 26-30, 2010 Invited Speaker, Glial Biology in Medicine Symposium Birmingham, Alabama December 5-7, 2010 Invited Speaker, National MS Society, Georgia Chapter The Future of MS Atlanta, Georgia January 21-22, 2011 Invited Speaker, SONTAG Foundation Retreat White Oaks, Florida February 8-10, 2011 Organizer, UAB Multiple Sclerosis Symposium Birmingham, Alabama April 1-2, 2011 Invited Participant/Speaker, NCI Translational Science Meeting From Molecular Information to Cancer Medicine Washington, D.C. July 28-29, 2011 Invited Participant, Immunology of Autism Think Tank Autism Speaks New York, New York August 22-23, 2011

Benveniste

Invited Symposium Speaker, 10th European Meeting on Glial Cells in Health and Disease Prague, Czech Republic September 13-17, 2011 Invited Speaker, JAK-STAT 20th Anniversary Symposium, NIH September 22-24, 2011 Invited Speaker, University of Rochester Rochester, New York December 1-2, 2011 Invited Speaker, Association of Medical School Pharmacology Chairs Annual Meeting Maui, Hawaii January 26-30, 2012 Invited Speaker, American Society of Neurochemistry, Pre-meeting Workshop on Glial Cells in Pathophysiology Baltimore, MD March 3, 2012 Invited Speaker, University of Pennsylvania Philadelphia, Pennsylvania March 20, 2012 Invited Speaker, Emory University Atlanta, Georgia March 26, 2012 Invited Speaker, MDA Glial Meeting Tucson, Arizona May 20-22, 2012 Invited Chair and Speaker, FASEB Summer Conference, Neural-Immune Interactions Carefree, Arizona July 29-August 3, 2012 Invited Participant, Brain Tumor Funders’ Collaborative (BTFC) Workshop Changing the Future of Glioblastoma: Understanding the Pre and Post Treatment Milieu St. Louis, Missouri October 22-24, 2012 Invited Speaker, Multiple Sclerosis Symposium New Therapeutic Approaches and Mechanistic Insights Ann Arbor, Michigan October 25-26, 2012 Plenary Speaker, 15th Annual Florida International University Biomedical and Comparative Immunology Symposium March 7-8, 2013

Invited Speaker/ Chair, Satellite Meeting of the 24th Biennial Joint Meeting ISN-ASN Understanding Glial Cell Functions in the Normal and Injured CNS Merida, Yucatan April 17-19, 2013

Organizer, UAB Multiple Sclerosis Symposium Birmingham, Alabama May 15-17, 2013

Invited Speaker, Southern Research Institute Birmingham, Alabama May 21, 2013

Invited Participant, Advisory Board for Novartis Oncology Dysregulation of the JAK-STAT Pathway in Solid Tumors and the Potential Role of Ruxolitinib Chicago, Illinois May 30, 2013

Benveniste

Invited Speaker, Southeastern Immunology Conference Birmingham, Alabama June 22-23, 2013 Invited Speaker, Nencki Institute of Experimental Biology Warsaw, Poland September 9-10, 2013 Invited Speaker, 7th International Conference on Protein Kinase CK2 Lublin, Poland September 10-13, 2013 Invited Speaker, Texas A&M College Station, Texas January 22-23, 2014

Invited Speaker, Wright State University Dayton, Ohio February 20-21, 2014

Invited Panel Discussant, Council for Faculty and Academic Societies (CFAS) Meeting Nashville, TN March 6, 2014 Session Chair/ Invited Speaker, American Society for Neurochemistry Long Beach, California March 8-12, 2014

Invited Speaker, University of Virginia Charlottesville, Virginia June 18-19, 2014

Co-Chair/Invited Speaker, Brain Tumors: From Biology to Therapy, 2014 Warsaw, Poland June 26-28, 2014 Invited Speaker/Chair, FASEB Summer Conference Translational Neuroimmunology: From Mechanisms to Therapeutics Big Sky, Montana July 13-18, 2014

Invited Speaker, UT San Antonio San Antonio, Texas September 4-5, 2014 Invited Presenter, Michael J. Fox Foundation Awardee Meeting New York, New York September 8-9, 2014 Invited Speaker, Glia Biology in Health and Disease Symposium Montevideo, Uruguay October 2-6, 2014 Invited Speaker, Glial Biology in Medicine Conference Birmingham, AL October 14, 2014 Invited Discussant, Society for Neuro-Onocology

Benveniste

Tumor Microenvironment and Heterogeneity Session Miami Beach, Florida November 13-17, 2014 Invited Speaker, Cleveland Clinic Cleveland, Ohio December 2-3, 2014 Invited Speaker, Case Western Reserve University Cleveland, Ohio December 3-4, 2014 Session Chair/Invited Speaker, American Society for Neurochemistry Atlanta, Georgia March 13-18, 2015 Invited Speaker, National Institutes of Health, NCI Bethesda, Maryland April 16-17, 2015 Invited Speaker, Symposium on CNS Autoimmune Disease and the Innate Immune System: Novel Roles of Pro-inflammatory and Regulatory Myeloid Cells, FOCIS Meeting San Diego, California June 24-25, 2015 Invited Speaker, Satellite Meeting of the ISN/APSN Meeting Understanding the Function of Glia in the Healthy and Diseased CNS Syndney, Australia August 19-22, 2015 Invited Speaker, American Brain Tumor Association Alumni Meeting Chicago, Illinois September 16-17, 2015 Invited Speaker, CYTOKINES 2015 Bamberg, Germany October 11-14, 2015 Invited Speaker, McGill University CIHR- Neuroinflammation Training Program Montreal, Quebec, Canada December 2-4, 2015 Invited Speaker, University of Minnesota Minneapolis, Minnesota December 16, 2015 Invited Speaker, JAK/STAT Signaling, Keystone Symposium Steamboat Springs, Colorado January 10-14, 2016 Invited Speaker, Blood Center of Wisconsin Milwaukee, Wisconsin January 18-19, 2016 Invited Speaker, MD Anderson Cancer Center Houston, Texas

Benveniste

February 10-11, 2016 Invited Speaker, STAT3 in Cancer, Cold Spring Harbor Laboratory Cold Spring Harbor, New York March 15-18, 2016 Invited Plenary Speaker, American Society for Neurochemistry Denver, Colorado March 18-23, 2016 Plenary Speaker, Spring Brain Conference Sedona, Arizona April 7-10, 2016 Invited Speaker, Temple University Philadelphia, Pennsylvania May 5-6, 2016 Block Chair, American Association of Immunologists Regulating the Outcome of T Helper Cell Differentiation Seattle, Washington May 14-17, 2016 Invited Speaker, Conference Co-Organizer, Brain Tumors: From Biology to Therapy, 2016 Warsaw, Poland June 26-30, 2016 Invited Speaker, 2016 FASEB Neuroimmunology Conference Big Sky, Montana July 24-29, 2016 Invited Speaker, 8th International Conference on Protein Kinase CK2 Homberg, Germany September 6-9, 2016 Invited Speaker, University of Nebraska Omaha, Nebraska October 13-14, 2016 Invited Participant, Michael J. Fox Foundation Role of Inflammation in Parkinson’s Disease New York, New York October 25-27, 2016 Invited Speaker, AAMC Annual Meeting “Exploring Resilience: An Evidence-Based Institutional Response” “Enhancing Support for the Academic Mission” Seattle, Washington November 11-15, 2016 Invited Speaker, Society for Neuro Oncology Scottsdale, Arizona November 17-20, 2016 Invited Speaker, Gordon Research Conference Neuroimmune Communication in Health and Disease Ventura, California

Benveniste

January 15-20, 2017 Invited Judge, ACTRIMS Meeting Orlando, Florida February 23-25, 2017 Invited Speaker, Council for Faculty and Academic Societies (CFAS) Annual Meeting “Faculty of Tomorrow’s Academic Health Center” “Discovery Science in the Biomedical Research Center” Orlando, Florida March 9-11, 2017 Organizer, UAB Multiple Sclerosis Symposium Birmingham, Alabama June 1-2, 2017 Invited Speaker, Synthetic Immunity Conference Sante Fe, New Mexico July 10-17, 2017 Invited Speaker, Johns Hopkins University, School of Medicine Baltimore, Maryland December 4-5, 2017 Session Chair/Invited Speaker, American Society of Neurochemistry Riverside, California March 24-28, 2018 Co-Facilitator, Council for Faculty and Academic Societies (CFAS) Annual Meeting “Practical Strategies for Basic Science Faculty Engagement in Governance and Leadership” Chicago, Illinois April 19-21, 2018 Invited Speaker, Consortium of Multiple Sclerosis Centers Nashville, Tennessee May 30-June 2, 2018 Invited Speaker, Conference Co-Organizer, Brain Tumors: From Biology to Therapy, 2018 Warsaw, Poland June 20-24, 2018 Invited Speaker, 143rd Annual Meeting of The American Neurological Association “Inflammation and Neurological Disease: Friend or Foe” Atlanta, Georgia October 21-23, 2018 Invited Speaker, AAMC Annual Meeting “Revitalizing and Invigorating the Ph.D. Education” Austin, Texas November 2-6, 2018 Invited Discussion Leader, Gordon Research Conference Co-Leader, Power Hour Neuroimmune Communication in Health and Disease Ventura, California January 13-18, 2019

Benveniste

Invited Speaker, AAMC, Council for Faculty and Academic Societies (CFAS) Annual Meeting “Changes in Ph.D. Education” Atlanta, Georgia April 4-6, 2019 Invited Speaker and Organizer, AAMC, Group on Research Advancement and Development (GRAND) Annual Meeting “Space Infrastructure and Strategic Planning” Washington, DC April 23-26, 2019 Invited Speaker, Brain/Brain PET 2019 Yokohama, Japan July 3-8, 2019 Co-Chair, Young Investigators Forum in Neuro-Oncology Atlanta, Georgia July 24-26, 2019 Co-Organizer/Speaker, 3rd America’s School of Neuroimmunology Montreal, Canada September 23-26, 2019 Invited Speaker, 17th International Congress of Immunology Beijing, China October 19-23, 2019 Invited Speaker, 2020 FASEB Translational Neuroimmunology Conference Babson Park, MA July 19-23, 2020 GRANT SUPPORT: PAST National Science Foundation, August 15, 1987 - January 31, 1991, #BNS-8708233. Principal Investigator: E.N. Benveniste. National Multiple Sclerosis Society, October 1, 1987 - September 30, 1990, #RG 1954-A-2. Principal Investigator: E.N. Benveniste. National Institute of Health, September 1, 1988 - August 31, 1993, PO1AI27290. E.N. Benveniste, Project Leader. National Multiple Sclerosis Society, April 1, 1990 - September 30, 1993, #RG 2205-A-3. Principal Investigator: E.N. Benveniste. National Multiple Sclerosis Society, October 1, 1990 - March 31, 1994, #RG 2269-A-4. Principal Investigator: E.N. Benveniste. National Institutes of Health, September 30, 1991 - May 31, 1996, P01 NS29719. Molecular Immunopathogenesis of Demyelinating Disease. Principal Investigators: J.N. Whitaker and E.N. Benveniste; Project Leader, E.N. Benveniste. Human Glial Tumors. Principal Investigator: S.S. Rosenfeld, Project 1: Tumor Necrosis Factor-alpha Gene Expression in Malignant Glioma Cells. E.N. Benveniste, Project Leader. National Multiple Sclerosis Society, November 1, 1993 - April 30, 1995, #PPO343. Principal Investigator: E.N. Benveniste. National Institutes of Health, September 1, 1993 - August 31, 1996, R01 MH50421. Astrocyte Cytokine Expression/Ion Transport in ADC. Principal Investigator: D.J. Benos, Co-Investigator: E.N. Benveniste. National Multiple Sclerosis Society, October 1, 1993 - March 31, 1997, #RG 2205-B-5. Cloning and Characterization of the Astrocyte Derived Nuclear Protein IFNEX. Principal Investigator: E.N. Benveniste. Berlex Laboratories, August 1, 1994 - December 31, 1995. Principal Investigator: E.N. Benveniste.

Benveniste

AmFAR, August 1, 1995 - August 31, 1996. 02405-18-RG. Class II MHC and ICAM-1: Involvement in ADC. Principal Investigator: E.N. Benveniste. National Multiple Sclerosis Society, April 1, 1994 - September 30, 1997, #RG 2269-B-5. Regulation of TNF-α Gene Expression by Glial Cells. Principal Investigator: E.N. Benveniste. National Institutes of Health, September 30, 1997 - July 31, 2000. R01 NS36765-01. Cytokine Regulation of CIITA and Class II MHC in Glia. Total Direct Costs: $400,000. Principal Investigator: E.N. Benveniste. National Multiple Sclerosis Society, April 1, 1997 – September 30, 2000, #RG 2205-B-9. CIITA and Class II MHC Expression in Glia: Inhibition by TGF-β and IL-4. Total Direct Costs: $126,360. Principal Investigator: E.N. Benveniste. Health Services Foundation, December 1, 1997 - July 31, 2000. NeuroAIDS Consortium. Total Costs: $74,960 Principal Investigator: E.N. Benveniste. National Institutes of Health, June 18-23, 2000. F13 NS 40010-01. FASEB Summer Conference on Neuroimmunology. Total Direct Costs: $11,650. Principal Investigator: E.N. Benveniste. National Institutes of Health, September 30, 1995 - April 30, 2001, R01 MH55795. HIV gp120 Induction of ICAM-1: Involvement in ADC. Total Direct Costs: $710,669. Principal Investigator: E.N. Benveniste. National Institutes of Health, October 1, 1996 - April 30, 2001, R01 MH50421-04. Astrocyte Cytokine Expression/Ion Transport in ADC. Total Direct Costs: $773,540. Principal Investigator: D.J. Benos, Co-Investigator: E.N. Benveniste. National Institutes of Health, June 1, 1996 - March 31, 2002, P01 NS29719-06. Molecular Immunopathogenesis of Demyelinating Disease. Principal Investigators: J.N. Whitaker and E.N. Benveniste. Project 1: ICAM-1 Expression in Glial Cells: Expression and Function. Total Direct Costs on Project 1: $739,023. (One-year, no-cost extension) E.N. Benveniste, Project Leader. American Foundation for AIDS Research, 06/01/01 – 05/31/02. CD40/CD154 Mediated Reactivation of Latent HIV-1 Infection. Total Direct Costs: $60,000. Principal Investigator: E.N. Benveniste. National Institutes of Health, August 17-22, 2002. R13 AG20989 FASEB Summer Conference on Neuroimmunology. Total Direct Costs: $26,875. Principal Investigator: E.N. Benveniste. National Institutes of Health, March 15, 1997 - March 14, 2003. P01 NS34856-01. Molecular and Cellular Biology of Human Glial Tumors. Principal Investigators: S.S. Rosenfeld and E.N. Benveniste. Project 1: ICAM-1 Gene Expression in Malignant Glial Tumors. Total Direct Costs on Project 1: $668,235. (One-year, no-cost extension) E.N. Benveniste, Project Leader. National Institutes of Health, June 7, 2001 – May 31, 2005. RO1 MH63650 CXCR4 Expression and Function in Astrocytes. Total Direct Costs: $600,000. Principal Investigator: E.N. Benveniste. National Institutes of Health, March 1, 2000 – February 28, 2005. No-cost extension until Feb. 28, 2006. RO1 NS39954-01. IL-6 Type Cytokines: Regulation of IL-6 Expression in Astrocytes. Total Direct Costs: $1,000,000. Principal Investigator: E.N. Benveniste. National Institutes of Health, August 1, 2000 – July 31, 2005. No-cost extension until July 31, 2006. 2RO1 NS36765-04 Cytokine Regulation of CIITA and Class II MHC in Glia. Total Direct Costs: $1,125,000. Principal Investigator: E.N. Benveniste. National Multiple Sclerosis Society, June 1, 2005 – November 31, 2006. NMSS PP1129 Novel Inhibitory Mechanisms of Statins: Influence on STAT and SOCS Proteins. Total Direct Costs: $40,000. Principal Investigator: E.N. Benveniste. National Institutes of Health, September 5, 2002 – May 31, 2007. No cost extension through May 31, 2008. P50 CA097247 SPORE in Molecular Therapeutics for Anaplastic Gliomas. Principal Investigator S.S. Rosenfeld. Project 2, Interferon-Mediated Suppression of MMP-9 Gene Expression and Function in Gliomas. Total Direct Costs: $884,225. Project Leader: E.N. Benveniste. National Institutes of Health, February 15, 2006 - January 31, 2008. No cost extension through January 31, 2009. R21 NS54158 Role of ING4 in Modulating the Tumorigenic Contribution of NF-κB in Gliomas. Total Direct Costs: $247,500. Principal Investigator: E.N. Benveniste. National Institutes of Health, July 15, 2003 – June 30, 2008. No cost extension through June 30, 2009. R01 NS45290 CD40 Expression and Function in Microglia. Total Direct Costs: $1,070,000. Principal Investigator: E.N. Benveniste. National Multiple Sclerosis Society, April 1, 2005 – March 31, 2009. RG 3661-A-10 TRADD as a Regulator of Cytokine Signaling in Macrophages and Microglia. Total Direct Costs: $134,986. Principal Investigator: E. N. Benveniste. National Multiple Sclerosis Society, October 1, 2006 – September 30, 2010. RG-3892-A-12 Expression and Function of SOCS Proteins in Glia. Total Direct Costs: $424,398. Principal Investigator: E. N. Benveniste.

Benveniste

National Institutes of Health, August 19, 2005 – May 31, 2011. (No-cost extension). R01 NS50665 TRADD as a Regulator of Cytokine Signaling in Glia. Total Direct Costs: $1,040,000. Principal Investigator: E. N. Benveniste. National Institutes of Health, July 20, 2009 – August 31, 2012. 3R01 NS057563-02S1 Expression and Function of SOCS Proteins in Glial Cells. Total Direct Costs $55,800. Principal Investigator: E. N. Benveniste. National Institutes of Health, September 15, 2011 – August 31, 2012. 5P50CA-089019-09. SPORE in Breast Cancer. Principal Investigator: K.I. Bland. Pilot Project: IL-6 Activation of the JAK/STAT3 Pathway in Breast Cancer: Therapeutic Implications for Protein Kinase CK2. Total Direct Costs $50,000. National Institutes of Health, December 15, 2007 – December 14, 2012. NCE December 15, 2012 - December 14, 2013. R01 NS57563-A1 Expression and Function of SOCS Proteins in Glial Cells. Total Direct Costs $800,000. Principal Investigator: E.N. Benveniste. National Multiple Sclerosis Society, April 1, 2013 – March 31, 2016. Therapeutic Intervention of the JAK/STAT Pathway for Neuroinflammation. Total Direct Costs $478,790. Principal Investigator: E. N. Benveniste. Relinquished on September 14, 2013 due to award of overlapping NIH grant. Southeastern Brain Tumor Foundation, February 1, 2012 – January 31, 2014. Defining the Role of NF-κB in Promoting STAT3 Activation in Malignant Glioma. Total Direct Costs $70,000. Principal Investigator: E. N. Benveniste. National Multiple Sclerosis Society, November 1, 2009 – October 31, 2014. Collaborative MS Research Center Award. Total Direct Costs $750,000. Principal Investigator: E.N. Benveniste. NCE to June 1, 2015. National Institutes of Health, March 1, 2012 – February 28, 2017. NCE until February 28, 2018. R01 CA-158534-01 Targeting the JAK2/STAT-3 Pathway Signaling Axis in Glioma. Total Direct Cost $1,000,000. Principal Investigator: E.N. Benveniste. National Institutes of Neurological Disorders and Stroke, July 1, 2015 – June 30, 2017. NCE until June 30, 2018. P20NS092530. Innate and Adaptive Immunity in Parkinson Disease. Total Direct Costs $500,000. Project Leader: E. N. Benveniste. Michael J. Fox Foundation, February 2017 – May 2018. The Role of the JAK/STAT Pathway in Human Parkinson's Disease. Total Direct Costs $80,000. Principal Investigator: E. N. Benveniste. GRANT SUPPORT: CURRENT National Institutes of Health, July 01, 2013 - June 30, 2018. NCE to June 30, 2020. T32 NS48039-06. Training Program in Brain Tumor Biology. Total Direct Costs $1,300,875. Principal Investigator: E. N. Benveniste. National Institutes of Health, September 1, 2013 – August 31, 2018. NCE to August 31, 2019. R01 NS57563-05A1. Therapeutic Intervention of the JAK/STAT Pathway for Neuroinflammation. Total Direct Costs $1,250,000. Principal Investigator: E. N. Benveniste. National Institutes of Health, December 1, 2015 – November 30, 2020. R01CA194414-01A1. The Role of CK2 in Glioblastoma Development. Total Direct Costs $1,180,000. Principal Investigator: E. N. Benveniste. National Multiple Sclerosis Society, April 1, 2017-March 31, 2020. Function of Protein Kinase CK2 in CD4+ T cells and Autoimmune Disease. Total Direct Costs $600,000. Co-Principal Investigator: E. N. Benveniste. National Institutes of Health- Udall Center. July 1, 2018- June 30, 2023. P50 NS108675. Innate and Adaptive Immunity in Parkinson Disease. D. G. Standaert, P. I. Project 2: Validating the JAK/STAT Pathway as a Novel Therapeutic Strategy in PD. Total Direct Costs $7,570,900. Project Leader: E. N. Benveniste. Michael J. Fox Foundation, March 1, 2019 – February 28, 2020. Phenotypic Characterization of Human B-cells in Parkinson's Disease. Total Direct Costs $75,000. Principal Investigator: E. N. Benveniste. Department of Defense. October 1, 2019 - September 30, 2022. BC181709. Collapsing the Tumor-supportive Immune Portfolio of Breast Cancer to Achieve Durable Reduction of Metastasis. Total Direct Costs $166,666. Co- Investigator: E. N. Benveniste. GRANT SUPPORT: PENDING National Institutes of Health, July 01, 2020 - June 30, 2025. T32 NS48039-11. Training Program in Brain Tumor Biology. Total Direct Costs $1,300,875. Principal Investigator: E. N. Benveniste. Biomedical Research Facilities (C06 Clinical Trial Not Allowed), October 1, 2019 – September 20, 2024. Enhancing Core Capacity for Translational Research at the University of Alabama at Birmingham. Total Direct Cost $7,933,890. Principal Investigator: E. N. Benveniste

Benveniste

BIBLIOGRAPHY: 1. Lum, L.G., Benveniste, E., and R.M. Blaese. 1980. Functional properties of human T–cells bearing Fc

receptors for IgA. I. Mitogen responsiveness, mixed lymphocyte culture reactivity and helper activity for B–cell immunoglobulin production. J. Immunol. 124:702-707.

2. Stevens, R.H., Benveniste, E., and E. Pineda. 1982. The selective role of membrane IgG in the antigen-induced inhibition of human in vitro antibody synthesis. J. Immunol. 128:398-401.

3. Stevens, R.H., Benveniste, E., and D. Diechek. 1982. The selective role of membrane IgG in the antigen-induced inhibition of human in vitro antibody production. Symposium on Immunological Tolerance to Self and Non-Self. New York Acad. Sci. 291:416-417.

4. Benveniste, E., and R.H. Stevens. 1983. T–suppressor cells are required for the maintenance of the antigen-induced B-cell unresponsive state in humans. J. Clin. Immunol. 3:166-172.

5. Benveniste, E., Schroff, R., Stevens, R.H., and M.S. Gottlieb. 1983. Immunoregulatory T–cells in men with a new acquired immunodeficiency syndrome. J. Clin. Immunol. 3:359-367.

6. Lum, L.G., Benveniste, E., Steinberg, A.D., Blaese, R.M., and T.A. Waldmann. 1983. The distribution of TA, TG, and TM in various immunodeficiency and autoimmune disorders. Cell. Immunol. 80:105-113.

7. Gottlieb, M.S., and E. Benveniste. 1984. B–cell abnormalities in AIDS. N. Engl. J. Med. 310:259. 8. Benveniste, E.N., Merrill, J.E., Kaufman, S.E., Golde, D.W., and J.C. Gasson. 1985. Purification and

characterization of human T–lymphocyte derived glial growth promoting factor. Proc. Natl. Acad. Sci. USA 82:3930-3934.

9. Benveniste, E.N., Kutsunai, S., and J.E. Merrill. 1986. Immunoregulatory molecules modulate glial cell growth. In: Leukocytes and Host Defense, J.J. Oppenheim, ed., Alan R. Liss, Inc.: New York, New York, pp. 221-226.

10. Benveniste E.N., and J.E. Merrill. 1986. Interleukin–2 stimulation of oligodendroglial proliferation and maturation. Nature. 321:610-613.

11. Rodriguez, M., Lennon, V.A., Benveniste, E.N., and J.E. Merrill. 1987. Remyelination by oligodendrocytes stimulated by antiserum to spinal cord. J. Neuropathol. Exp. Neurol. 46:84-95.

12. Benveniste, E.N., Herman, P.K., and J.N. Whitaker. 1987. Myelin basic protein specific RNA levels in interleukin–2 stimulated oligodendrocytes. J. Neurochem. 49:1274-1279.

13. Benveniste, E.N., Tozawa, H., Gasson, J.C., Quan, S., Golde, D.W., and J.E. Merrill. 1988. Response of human glioblastoma cells to recombinant interleukin–2. J. Neuroimmunol. 17:301-314.

14. Benveniste, E.N. 1988. Lymphokines and monokines in the neuroendocrine system. In: Progress in Allergy: Neuroimmunoendocrinology. Vol. 43, J.E. Blalock, ed. (S. Karger, Basel), pp. 84-120.

15. Benveniste, E.N., Butler, J.L., Gibbs, D.A., Chen, A., and J.N. Whitaker. 1988. Rat astrocyte proliferation by human B–cell growth factors. In: Advances in Neuroimmunology. Vol. 540, C.S. Raine, ed. (New York Academy of Science), pp. 392-395.

16. Whitaker, J.N., Sparks, B.E., Walker, D.P., Goodin, R., and E.N. Benveniste. 1989. Monoclonal idiotypic and anti-idiotypic antibodies produced by immunization with peptides specified by a region of human myelin basic protein mRNA and its complement. J. Neuroimmunol. 22:157-166.

17. Blalock, J.E., Whitaker, J.N., Benveniste, E.N., and K.L. Bost. 1989. Use of peptides encoded by complementary RNA for generating anti-idiotypic antibodies of predefined specificity. Meth. Enzymol. 178:63-74.

18. Benveniste, E.N., Whitaker, J.N., Gibbs, D.A., Sparacio, S.M., and J.L. Butler. 1989. Human B cell growth factor enhances proliferation and glial fibrillary acidic protein gene expression in rat astrocytes. Inter. Immunol. 1:219-228.

19. Benveniste, E.N., Sparacio, S.M., and J.R. Bethea. 1989. Tumor necrosis factor alpha enhances interferon-gamma mediated Class II antigen expression on astrocytes. J. Neuroimmunol. 25:209-219.

20. Whitaker, J.N., and E.N. Benveniste. 1990. Demyelinating diseases. In: The Neurobiology of Disease, A. Pearlman and R. Collins, eds., Oxford University Press, pp. 323-338.

21. Whitaker, J.N., Benveniste, E.N., and S-r. Zhou. 1990. Cerebrospinal fluid. In: Handbook of Multiple Sclerosis, S.D. Cook, ed., Marcel Dekker Inc, pp. 251-270.

22. Chung, I.Y., and E.N. Benveniste. 1990. Tumor necrosis factor production by astrocytes: Induction by lipopolysaccharide, interferon-gamma and interleukin–1. J. Immunol. 144:2999-3007.

23. Bethea, J.R., Gillespie, Y.G., Chung, I.Y., and E.N. Benveniste. 1990. Tumor necrosis factor production and receptor expression by a human malignant glioma cell line D54-MG. J. Neuroimmunol. 30:1-13.

24. Vidovic, M., Sparacio, S.M., Elovitz, M., and E.N. Benveniste. 1990. Induction and regulation of class II MHC mRNA expression in astrocytes by IFN–γ and TNF–α. J. Neuroimmunol. 30:189-200.

Benveniste

25. Benveniste, E.N., Sparacio, S.M., Norris, J.G., Grenett, H.E., and G.M. Fuller. 1990. Induction and regulation of interleukin–6 gene expression in rat astrocytes. J. Neuroimmunol. 30:201-212.

26. Chung, I.Y., Norris, J.G., and E.N. Benveniste. 1991. Differential TNF-α expression by astrocytes from experimental allergic encephalomyelitis susceptible and resistant rat strains. J. Exp. Medicine 173:801-811.

27. Whitaker, J.N., Herman, P.K., Sparacio, S.M., Zhou, S-r., and E.N. Benveniste. 1991. Changes induced in astrocyte cathepsin D by cytokines and leupeptin. J. Neurochem. 57:406-414.

28. Benveniste, E.N., Vidovic, M., Panek, R.B., Norris, J.G., Reddy, A.T., and D.J. Benos. 1991. Interferon-γ induced astrocyte class II MHC gene expression is associated with both Na+ entry and protein kinase C. J. Biol. Chem. 266:18119-18126.

29. Bethea, J.R., Chung, I.-Y., Sparacio, S.M., Gillespie, G.Y., and E.N. Benveniste. 1992. Interleukin-1β induction of tumor necrosis factor-alpha gene expression in human astroglioma cells. J. Neuroimmunol. 36:179-191.

30. Benveniste, E.N. 1992. Cytokines: Influence on glial cell gene expression and function. In: Chemical Immunology: Neuroimmunoendocrinology 2nd, revised edition. Vol. 52, pp. 106-153, J.E. Blalock, ed. S. Karger, Basel.

31. Adachi, K., Belser, P., Li, D., Rodeck, U., Bender, H., Benveniste, E.N., Woo, D., Schmiegel, W.H., and D. Herlyn. 1992. Enhancement of epidermal growth factor receptor (EGF-R) expression on glioma cells by recombinant tumor necrosis factor (rTNF)-α. Cancer Immunol. Immunother. 34:370-376.

32. Moses, H., Panek, R.B., Benveniste, E.N., and J. P-Y. Ting. 1992. Usage of primary cells to delineate IFN-γ responsive DNA elements in the HLA-DRA promoter and to identify a novel IFN-γ enhanced nuclear factor (IFNEX). J. Immunol. 148:3643-3651.

33. Barnum, S.R., Jones, J., and E.N. Benveniste. 1992. Interferon-γ regulation of C3 gene expression in human astroglioma cells. J. Neuroimmunol. 38:275-282.

34. Benveniste, E.N. 1992. Inflammatory cytokines within the central nervous system: Sources, function and mechanism of action. Amer. J. Physiol: Cell. Physiol. 32:C1-C16 (Invited Review).

35. Bethea, J.R., Gillespie, G.Y., and E.N. Benveniste. 1992. Interleukin-1β induction of TNF-α gene expression: Involvement of protein kinase C. J. Cell. Physiol. 152:264-273.

36. Sparacio, S.M., Zhang, Y., Vilcek, J., and E.N. Benveniste. 1992. Regulation of interleukin-6 gene expression in astrocytes involves activation of an NF-κB-like nuclear protein. J. Neuroimmunol. 39:231-242.

37. Panek, R.B., Moses, H., Ting, J. P.-Y., and E.N. Benveniste. 1992. Tumor necrosis factor-alpha response elements in the HLA-DRA promoter: Identification of a novel TNF-α induced DNA-protein complex in astrocytes. Proc. Natl. Acad. Sci. U.S.A. 89:11518-11522.

38. Chung, I.Y., Kwon, J.B. and E.N. Benveniste. 1992. Role of protein kinase C activity in TNF-α gene expression: Involvement at the transcriptional level. J. Immunol. 149:3894-3902.

39. Benveniste, E.N. 1993. Astrocyte - Microglia Interactions. In: Astrocytes: Pharmacology and Function, S. Murphy, ed. Academic Press, pp. 355-382.

40. Barnum, S.R., Jones, J.L., and E.N. Benveniste. 1993. Interleukin-1β and tumor necrosis factor mediated regulation of C3 gene expression in human astroglioma cells. Glia. 7:225-23.

41. Norris, J.G., and E.N. Benveniste. 1993. Interleukin-6 production by astrocytes: Induction by the neurotransmitter norepinephrine. J. Neuroimmunol. 45:137-146.

42. Kwon, J., Chung, I.Y., and E.N. Benveniste. 1993. Cloning and sequence analysis of the rat tumor necrosis factor - encoding genes. Gene. 132:227-236.

43. Chung, I.Y., Kwon, J.B., and E.N. Benveniste. 1993. Regulation of tumor necrosis factor-alpha gene expression in the astrocyte. In: Biology and Pathology of Astrocyte-Neuron Interactions. S. Federoff, B.H.J. Juurlink and R. Doucette, eds. (Plenum Press). Vol. 2 pp. 237-246.44.

44. Baldwin, G.C., Benveniste, E.N., Chung, G.Y., Gasson, J.C., and D.W. Golde. 1993. Identification and characterization of a high-affinity GM-CSF receptor on primary rat oligodendrocytes. Blood. 82:3279-3282.

45. Norris, J.G., Tang, L.-P., Sparacio, S.M., and E.N. Benveniste. 1994. Signal transduction pathways mediating astrocyte IL-6 induction by IL-1β and tumor necrosis factor-α. J. Immunol. 152:841-850.

46. Benveniste, E.N. 1994. Cytokine circuits in brain: Implications for AIDS Dementia Complex. In: HIV, AIDS, and the Brain. R. W. Price and S. W. Perry, eds. ARNMD, Vol. 72 (Raven Press). pp. 71-88.

Benveniste

47. Benos, D.J., Hahn, B.H., Bubien, J.K., Ghosh, S.K., Mashburn, N.A., Chaikin, M.A., Shaw, G.M., and E.N. Benveniste. 1994. Envelope glycoprotein gp120 of human immunodeficiency virus type 1 alters ion transport in astrocytes: Implications for AIDS dementia complex. Proc. Natl. Acad. Sci. USA. 91:494-498.

48. Shrikant, P., Chung, I.Y., Ballestas, M., and E.N. Benveniste. 1994. Regulation of intracellular adhesion molecule-1 gene expression by tumor necrosis factor-α, interleukin-1β, and interferon-γ in astrocytes. J. Neuroimmunol. 51: 209-220.

49. Benos, D.J., McPherson, S., Hahn, B.H., Chaikin, M.A., and E.N. Benveniste. 1994. Cytokines and HIV envelope glycoprotein gp120 stimulate Na+/H+ exchange in astrocytes. J. Biol. Chem. 269:13811-13816.

50. Benos, D.J., Hahn, B.H., Shaw, G.M., Bubien, J.K., and E.N. Benveniste. 1994. gp120-mediated alterations in astrocyte ion transport. Advances in Neuroimmunol. 4:175-179.

51. Panek, R.B., Lee, Y.-J., Itoh-Lindstrom, Y., Ting, J.P.-Y., and E.N. Benveniste. 1994. Characterization of astrocyte nuclear proteins involved in IFN-γ and TNF-α mediated class II MHC gene expression. J. Immunol. 153:4555-4564.

52. Benveniste, E.N., Kwon, J.B., Chung, W.J., Sampson, J., Pandya, K. and L.P. Tang. 1994. Differential modulation of astrocyte cytokine gene expression by TGF-β. J. Immunol. 153:5210-5221.

53. Lee, Y.-J., Panek, R.B., Huston, M., and E.N. Benveniste. 1995. Role of protein kinase C and tyrosine kinase activity in IFN-γ induced expression of the class II MHC gene. Amer. J. Physiol: Cell. Physiol. 37:127-137.

54. Panek, R.B., Lee, Y.-J., and E.N. Benveniste. 1995. TGF-β suppression of IFN-γ induced class II MHC gene expression does not involve inhibition of phosphorylation of JAK1, JAK2 or STAT1α or modification of IFNEX expression. J. Immunol. 154:610-619.

55. Benveniste, E.N. 1995. The role of cytokines in multiple sclerosis/autoimmune encephalitis and other neurological disorders. In: Human Cytokines: Their Role in Research and Therapy, B. Aggarawal and R. Puri, eds. Blackwell Scientific Publications, pp. 195-216.

56. Rosenman, S.J., Shrikant, P., Dubb, L., Benveniste, E.N., and R.M. Ransohoff. 1995. Cytokine-induced expression of vascular cell adhesion molecule-1 (VCAM-1) by astrocytes and astrocytoma cell lines. J. Immunol. 154:1888-1899.

57. Panek, R.B., and E.N. Benveniste. 1995. Class II MHC gene expression in microglia: regulation by the cytokines IFN-γ, TNF-α and TGF-β. J. Immunol. 154:2846-2854.

58. Benveniste, E.N., Tang, L.P., and R.M. Law. 1995. Differential regulation of astrocyte TNF-α expression by the cytokines TGF-β, IL-6 and IL-10. Intl. J. Devel. Neurosci. 13:341-349.

59. Bubien, J.K., Benveniste, E.N., and D. J. Benos. 1995. HIV gp120 activates large conductance apamin-sensitive potassium channels in rat astrocytes. Amer. J. Physiol:Cell. Physiol. 37:6:C1440-C1449.

60. Shrikant, P., Weber, E., Jilling, T., and E.N. Benveniste. 1995. ICAM-1 gene expression by glial cells: differential mechanisms of inhibition by interleukin-10 and interleukin-6. J. Immunol. 155:1489-1501.

61. Ballestas, M., and E.N. Benveniste. 1995. Interleukin-1β and tumor necrosis factor-α mediated regulation of ICAM-1 gene expression in astrocytes requires protein kinase C activity. GLIA. 14:267-278.

62. Benveniste, E.N. 1995. Cytokine production. In: Neuroglia. B. R. Ransom and H. Kettenmann (eds.) Oxford University Press. pp. 700-716.

63. Huneycutt, B.S. and E.N. Benveniste. 1995. Regulation of astrocyte cell biology by the cAMP/protein kinase A signaling pathway. Advances in Neuroimmunol. 5:261-269 (Invited Review).

64. Benos, D.J., Bubien, J.K., Hahn, B.H., Shaw, G.M., and E.N. Benveniste. 1995. The role of the astrocyte in the pathogenesis in the AIDS dementia complex. In: Technical Advances in AIDS Research in the Nervous System. E. Major, ed. (Plenus). pp. 223-233.

65. Benveniste, E.N., and D.J. Benos. 1995. TNF-α and IFN-γ mediated signal transduction pathways: effects on glial cell gene expression and function. FASEB J. 9:1577-1584 (Invited Review).

66. Benveniste, E.N., B.S. Huneycutt, P. Shrikant and M.E. Ballestas. 1995. Second messenger systems in the regulation of cytokines and adhesion molecules in the central nervous system. Brain, Behavior and Immunity. 9:304-314. (Invited Review)

67. Patton, H.K., Benveniste, E.N., and D.J. Benos. 1996. Astrocytes and the AIDS dementia complex. J. Neuro-AIDS. 1:111-131 (Invited Review).

68. Shrikant, P., Benos, D.J., Tang, L.-P., and E.N. Benveniste. 1996. HIV gp120 enhances ICAM-1 gene expression in glial cells: Involvement of JAK/STAT and protein kinase C signaling pathways. J. Immunol. 156:1307-1314.

Benveniste

69. Benveniste, E.N. 1996. Overview: Cytokines and the CNS. In: Cytokines and the CNS: Development, Defense and Disease, E.N. Benveniste and R.M. Ransohoff, eds. CRC Press. Boca Raton, Florida. pp. 1-4.

70. Shrikant, P., Lee, S.J., Kalvakolanu, I., Ransohoff, R.M., and E.N. Benveniste. 1996. Stimulus-specific inhibition of ICAM-1 gene expression by TGF-β. J. Immunol. 157:892-900.

71. Merrill, J.E., and E.N. Benveniste. 1996. Cytokines in inflammatory brain lesions: Helpful and harmful. TINS. 19:331-338. (Invited Review)

72. Lee, Y.-J., and E.N. Benveniste. 1996. STAT-1α expression is involved in IFN-γ induction of the CIITA and class II MHC genes. J. Immunol. 157:1559-1568.

73. Whitaker, J.N. and E.N. Benveniste. 1996. Cerebrospinal fluid. In "Handbook of Multiple Sclerosis". S. D. Cook, ed. Marcel Dekker, Inc., New York. pp. 295-316.

74. Shrikant, P., and E.N. Benveniste. 1996. The central nervous system as an immunocompetent organ: role of glial cells in antigen presentation. J. Immunol. 157:1819-1822.

75. Kwon, J., Lee, S.J., and E.N. Benveniste. 1996. A 3' cis-acting element is involved in tumor necrosis factor-α gene expression in astrocytes. J. Biol. Chem. 271:22383-22390.

76. Rohn, W.M., Lee, Y.-J., and E.N. Benveniste. 1996. Regulation of class II MHC expression. Crit. Rev. Immunol. 16:311-330.

77. Barnes, D.A., Huston, M., Holmes, R., Benveniste, E.N., Yong, V.W., Scholz, P. and H.D. Perez. 1996. Induction of RANTES expression by astrocytes and astroglioma cell lines. J. Neuroimmunol. 71:207-214.

78. Chung, I.Y. and E.N. Benveniste. 1996. Cell surface expression of tumor necrosis factor-alpha by activated rat astrocytes. J. Biochem. Mol. Biol. 29:530-534.

79. Lee, Y.-J., Han, Y., Lu, H.-T., Nguyen, V., Qin, H., Howe, P.H., Hocevar, B.A., Boss, J., Ransohoff, R.M., and E.N. Benveniste. 1997. Transforming growth factor-β suppresses induction of class II MHC gene expression by inhibiting class II transactivator mRNA expression. J. Immunol. 158:2065-2075.

80. Benveniste, E.N. 1997. Role of macrophages/microglia in multiple sclerosis and experimental allergic encephalomyelitis. J. Mol. Med. 75:165-173.

81. Benveniste, E.N. 1997. Cytokine expression in the nervous system. In: Immunology of the Nervous System. R. W. Keane and W. F. Hickey (eds.) Oxford University Press. pp. 419-459.

82. Benveniste, E.N. 1997. Cytokines and the central nervous system. In: Cytokines in Health and Disease, 2nd Edition, D.G. Remick and J. S. Friedland, eds. Marcel Dekker, Inc., New York. pp. 531-556.

83. Ballestas, M.E., and E.N. Benveniste. 1997. Elevation of cAMP levels in astrocytes antagonizes cytokine-induced adhesion molecule expression. J. Neurochem. 69:1438-1448.

84. Benveniste, E.N. 1997. Cytokines: Influence on glial cell gene expression and function. In: Neuroimmunoendocrinology, 3rd Rev. Edition, J.E. Blalock, ed. Karger, Basel, pp.31-75.

85. Lyons, P.D., and E.N. Benveniste. 1998. Cleavage of membrane-associated ICAM-1 from astrocytes: Involvement of a metalloprotease. GLIA. 22:103-112.

86. Winkler, M., and E.N. Benveniste. 1998. TGF-β mediated inhibition of VCAM-1 expression in astroglioma cells. GLIA. 22:171-179.

87. Benveniste, E.N., Shrikant, S., Patton, H.K., and D.J. Benos. 1998. Neuroimmunologic mechanisms for disease in AIDS: The role of the astrocyte. In: The Neurology of AIDS, H.E. Gendelman, S.A. Lipton, L. Epstein and S. Swindells, eds. Chapman and Hall, New York, pp. 130-146.

88. Van Wagoner, N., O'Keefe, G.M., and E.N. Benveniste. 1998. Kinase inhibitors abrogate IFN-γ-induced class II transactivator and class II MHC gene expression in astroglioma cell lines. J. Neuroimmunol. 85:174-185.

89. Nguyen, V., Walker, W.S., and E.N. Benveniste. 1998. Post-transcriptional inhibition of CD40 gene expression in microglia by TGF-β. Eur. J. Immunol. 28:2537-2548.

90. Oh, J.-W., Van Wagoner, N., Rose-John, S., and E.N. Benveniste. 1998. Role of IL-6 and the soluble IL-6 receptor in inhibition of VCAM-1 gene expression. J. Immunol. 161:4992-4999.

91. Qin, H., Moellinger, J.D., Wells, A., Windsor, L.J., Sun, Y., and E.N. Benveniste. 1998. Transcriptional suppression of matrix metalloproteinase-2 gene expression in human astroglioma cells by TNF-α and IFN-γ. J. Immunol. 161:6664-6673.

92. Lee, S.J., Hou, J. and E.N. Benveniste. 1998. Transcriptional regulation of intercellular adhesion molecule-1 in astrocytes involves NF-κB and C/EBP isoforms. J. Neuroimmunol. 92:196-207

93. Benveniste, E.N. 1998. Cytokine actions in the central nervous system. Cytokine & Growth Factor Rev. 9:259-275. (Invited Review).

Benveniste

94. Lee, S.J., Park, J.Y., Hou, J., and E.N. Benveniste. 1999. Transcriptional regulation of the intercellular adhesion molecule-1 gene by proinflammatory cytokines in human astrocytes. GLIA 25:21-31.

95. Rohn, W.M., Tang, L.P., Dong, Y., and E.N. Benveniste. 1999. IL-1β inhibits IFN-γ induced class II MHC expression by suppressing transcription of the class II transactivator gene. J. Immunol. 162:886-896.

96. Oh, J.-W., Schwiebert, L. M., and E.N. Benveniste. 1999. Expression of CC and CXC chemokines by human astrocytes. J. Neurovirol. 5:82-94

97. O'Keefe, G. M., Nguyen, V., and E.N. Benveniste. 1999. Class II transactivator and class II MHC gene expression in microglia: modulation by the cytokines TGF-β, IL-4, IL-13 and IL-10. Eur. J. Immunol. 29:1275-1285.

98. Dong, Y., Rohn, W.M., and E.N. Benveniste. 1999. IFN-γ regulation of the Type IV CIITA promoter in astrocytes. J. Immunol. 162:4731-4739.

99. Van Wagoner, N., Oh, J.-W., Repovic, P., and E.N. Benveniste. 1999. IL-6 production by astrocytes: Autocrine regulation by IL-6 and the soluble IL-6 receptor. J. Neurosci. 19:5236-5244.

100. Collawn, J., and E.N. Benveniste. 1999. Regulation of MHC class II expression in the central nervous system. Microbes and Infection 1:893-902. (Invited Review).

101. Lee, S.J., and E.N. Benveniste. 1999. Adhesion molecule expression and regulation on cells of the central nervous system. J. Neurommunol. 98:77-88 (Invited Review).

102. Qin, H., Sun, Y., and E.N. Benveniste. 1999. The transcription factors Sp1, Sp3, and AP-2 are required for constitutive matrix metalloproteinase-2 gene expression in astroglioma cells. J. Biol. Chem. 274:29130-29137.

103. Woodman, S.E., Benveniste, E.N., Nath, A., and J.W. Berman. 1999. Human immunodeficiency virus type 1 Tat protein induces adhesion molecule expression in astrocytes. J. Neurovirol. 5:678-684

104. Van Wagoner, N., and Benveniste, E. N. 1999. Interleukin-6 expression and regulation in astrocytes. J. Neuroimmunol. 100:124-129 (Invited Review)

105. Lee, S. J., Zhou, T., Choi, C., Wang, Z., and E.N. Benveniste. 2000. Differential regulation and function of Fas expression on glial cells. J. Immunol.164:1277-1285

106. Gladson, C.D., Stewart, J.E., Jr., Olman, M.A., Chang, P.L., Schnapp, L.M., Grammer, J.R., and E.N. Benveniste. 2000. Attachment of primary neonatal rat astrocytes to vitronectin is mediated by integrins αvβ5 and α8β1: modulation by the type 1 plasminogen activator inhibitor. Neurosci. Lett. 283:157-161.

107. Van Wagoner, N., Choi, C., Repovic, P., and E.N. Benveniste. 2000. Oncostatin M regulation of IL-6 expression in astrocytes: biphasic regulation involving the mitogen-activated protein kinases ERK1/2 and p38. J. Neurochem. 75:563-575.

108. Nguyen, V., and E.N. Benveniste. 2000. Involvement of STAT-1 and ets family members in interferon-γ induction of CD40 transcription in macrophages/microglia. J. Biol. Chem. 275:23674-23684.

109. Patton, H.K., Bubien, J.K., Benveniste, E.N., and D.J. Benos. 2000. GP120-induced alterations of human astrocytic function: Na+/H+ exchange, K+ conductance, and glutamate flux. Am. J. Physiol. Cell. 279:C700-C708.

110. Kutsch, O., Oh, J.-W., Nath, A., and E.N. Benveniste. 2000. Induction of the chemokines interleukin-8 and IP-10 by Human Immunodeficiency Virus Type 1 Tat in astrocytes. J. Virol. 74:9214-9221.

111. Lee, S. J., Drabik, K., Van Wagoner, N., Lee, S., Choi, C., Dong, Y., and E.N. Benveniste. 2000. ICAM-1-induced expression of proinflammatory cytokines in astrocytes: involvement of ERK and p38 MAP kinase pathways. J. Immunol. 165:4658-4666.

112. Nguyen, V.T. and E.N. Benveniste. 2000. Interleukin-4 activated STAT-6 inhibits IFN-γ induced CD40 gene expression in macrophages/microglia. J. Immunol. 165:6235-6243.

113. Wang, D., Yamamoto, S. Hijiya, N., Benveniste, E.N. and C.L. Gladson. 2000. Transcription regulation of the human osteopontin promoter: functional analysis and DNA-protein interactions. Oncogene 19:5801-5809.

114. Benveniste, E.N. and N. Van Wagoner. 2000. Astrocytes and the neuroimmunomodulatory role of interleukin-6. In: New Concepts in the Immunopathogenesis of CNS Infections, P. K. Peterson and J. S. Remington, eds. Blackwell Science, Malden, MA, pp. 21-38.

115. Oh, J.-W., Drabik, K., Kutsch, O., Choi, C., Tousson, A. and E.N. Benveniste. 2001. CXCR4 expression and function in human astrogliomas. J. Immunol. 166:2695-2704.

116. O’Keefe, G.M., Nguyen, V.T., Tang, L.-P., and E.N. Benveniste. 2001. IFN-γ regulation of CIITA promoter IV in macrophages and microglia: involvement of the SOCS-1 protein. J. Immunol. 166:2260-2269.

117. Patton, H.K., Chu, W.J., Hetherington, H.P., denHollander, J., Stewart, K.E., Raper, J.L., Shelton, B.J.

Benveniste

Benveniste, E.N., and D.J. Benos. 2001. Alkaline pH changes in the cerebellum of asymptomatic HIV-infected individuals. NMR Biomed 14:12-18.

118. Choi, C., Xu, X., Oh, J.-W., Lee, S.J., Gillespie, G.Y., Park, H., Jo, H., and E.N. Benveniste. 2001. Fas-induced expression of chemokines in human glioma cells: Involvement of extracellular signal-regulated kinase 1/2 and p38 mitogen-activated protein kinase. Cancer Res. 61:3084-3091.

119. Whitaker, J.N., Bashir, K., and E.N. Benveniste. 2001. Cerebrospinal Fluid. In: Handbook of Multiple Sclerosis, Third Edition, S.D. Cook, ed. Marcel Dekker, Inc., New York, Basel, pp.347-375.

120. Hummel, V., Kallmann, B.A., Wagner, S., Fuller, T., Bayas, A., Tonn, J.C., Benveniste, E.N., Toyka, K. V., and P. Rieckmann. 2001. Production of MMPs in human cerebral endothelial cells and their role in shedding adhesion molecules. J. Neuropathol. Exp. Neurol. 60:320-327.

121. Dong, Y., Tang, L., Letterio, J. and E.N. Benveniste. 2001. The Smad3 protein is involved in transforming growth factor-β inhibition of class II transactivator and class II MHC expression. J. Immunol. 167:311-319.

122. Van Wagoner, N. and E.N. Benveniste. 2001. Cytokines. In: CONTINUUM – Lifelong Learning in Neurology, R.M. Ransohoff, ed. 7:34-55

123. Benveniste, E.N., Nguyen, V.T. and G.M. O’Keefe. 2001. Immunological aspects of microglia: relevance to Alzheimer’s Disease. Neurochemistry Intl. 39:381-391.

124. Dong, Y. and E.N. Benveniste. 2001. Immune function of astrocytes. GLIA, Special Issue: Neuroinflammation. 36:180-190.

125. Ma, Z.J., Qin, H., and E.N. Benveniste. 2001. Transcriptional suppression of matrix metalloproteinase-9 gene expression by IFN-γ and IFN-β: critical role of STAT-1α. J. Immunol. 167:5150-5159.

126. Lee, S.J., Drabik, K., and E.N. Benveniste. 2001. Cloning of rat calcium-modulating cyclophilin ligand. DNA Sequence. 12:209-213.

127. Han, X., Stewart, J.E., Bellis, S., Benveniste, E. N., Ding, Q., Tachibana, K., Grammer, J., and C. L. Gladson. 2001. TGF-β1 upregulates paxillin protein expression in malignant astrocytoma cells: requirement for a fibronectin substrate. Oncogene. 20:7976-7986.

128. Koul, D., Parthasarathy, R., Shen, R., Davies, M.A., Jasser, S.A., Chintala, S.K., Rao, J.S., Sun, Y., Benveniste, E.N., Liu, T.J., W.K.A. Yung. 2001. Suppression of matrix metalloproteinase-2 gene expression and invasion in human glioma cells by MMAC/PTEN. Oncogene. 20:6669-6678.

129. Choi, C., Park, J., Kutsch, O., Zhou, T., Seol, D.-W., and E.N. Benveniste. 2002. Tumor necrosis factor related apoptosis inducing ligand (TRAIL) induces caspase-dependent IL-8 expression and apoptosis in human astroglioma cells. Mol. Cell. Biol. 22:724-736.

130. Nguyen, V.T., and E.N. Benveniste. 2002. Critical role of TNF-α and NF-κB in IFN-γ induced CD40 expression in microglia/macrophages. J. Biol Chem. 277:13796-13803.

131. Choi, C., Gillespie, G. Y., Van Wagoner, N. J. and E.N. Benveniste. 2002. Fas engagement increases expression of interleukin-6 in human glioma cells. J. Neuro-Oncology 56:13-19.

132. Repovic, P. and E.N. Benveniste. 2002. PGE2 as a novel inducer of Oncostatin M production in macrophages. J. Neurosci. 22:5334-5343.

133. O’Keefe, G. M., Nguyen, V. T. and E.N. Benveniste. 2002. Regulation and function of class II MHC, CD40 and B7 expression in macrophages and microglia: Implications in neurological diseases. J. NeuroVirol. 6:496-512.

134. Wesemann, D.R., Dong, Y., O’Keefe, G.M., Nguyen, V.T. and E.N. Benveniste. 2002. Suppressor of cytokine signaling (SOCS)-1 inhibits cytokine induction of CD40 expression in murine macrophages. J. Immunol. 169: 2354-2360.

135. Kutsch, O., Benveniste, E.N., Shaw, G.M. and D.N. Levy. 2002. Direct and quantitative single cell analysis of HIV-1 reactivation from latency. J. Virol. 76:8776-8786.

136. Collawn, J.F., Zaliauskiene, L., and E.N. Benveniste. 2003. Interferons. In: Encyclopedia of Neurological Sciences. M. Aminoff and R. Daroff (eds). Academic Press, San Diego, California. Vol. 2, 674-680.

137. Park, J., Kwon, D., Choi, C., Oh, J.-W. and E.N. Benveniste. 2003. Chloroquine induces activation of NF-κB and subsequent expression of pro-inflammatory cytokines by human astroglial cells. J. Neurochem. 84:1266-1274.

138. Repovic, P., Mi, K., and E.N. Benveniste. 2003. Oncostatin-M enhances the expression of PGE2 and cyclooxygenase-2 in astrocytes. Synergy with interleukin-1β, tumor necrosis factor-α and bacterial LPS. GLIA. 42:433-446.

139. Kutsch, O., Levy, D. N., Kosloff, B. R., Shaw, G. M. and E.N. Benveniste. 2003. CD40:CD154-mediated reactivation of latent HIV-1 infection. Virology. 314:261-270.

Benveniste

140. Repovic, P., Fears, C.Y., Gladson, C.L., and E.N. Benveniste. 2003. Oncostatin-M induction of vascular endothelial growth factor expression in astroglioma cells. Oncogene. 22:8117-8124.

141. Wesemann, D.R. and E.N. Benveniste. 2003. IFN-γ and STAT-1α as modulators of TNF-α signaling in macrophages: Regulation and functional implications of the STAT-1α: TNFR1 complex. J. Immunol. 171:5313-5319.

142. Choi, K., Benveniste, E.N., and C. Choi. 2003. Induction of intercellular adhesion molecule-1 by Fas ligation: Proinflammatory role of fas in human astroglial cells. Neurosci. Lett. 352:21-24.

143. Wesemann, D.R. and E.N. Benveniste. 2004. Cytokine and chemokine receptors and signaling. In: Neuroglia, Second Edition. B.R. Ransom and H. Kettenmann (eds). Oxford University Press. 146-162.

144. Choi, C., and E.N. Benveniste. 2004. Fas Ligand/Fas system in the brain. Regulator of immune and apoptotic responses. Brain Research Reviews. 44:65-81.

145. Wesemann D.R., Qin, H., Kokorina, N., and E.N. Benveniste. 2004. TRADD interacts with STAT-1α and influences IFN-γ signaling. Nature Immunology. 5:199-207.

146. Benveniste, E.N., V.T. Nguyen and D.R. Wesemann. 2004. Molecular regulation of CD40 gene expression in macrophages and microglia. Brain, Behavior and Immunity. 18:7-12.

147. Olman, M.A., White, K.E., Ware, L.B., Simmons, W.L., Benveniste, E.N., Zhu, S., Pugin, J., and M. A. Matthay. 2004. Pulmonary edema fluid from patients with early lung injury stimulates fibroblast proliferation by interleukin-1β-induced IL-6 expression. J. Immunol. 172:2668-2677.

148. Choi, C., Jeong, E., and E.N. Benveniste. 2004. Caspase-1 mediates Fas-induced apoptosis and is up-regulated by interferon-γ in human astrocytoma cells. J. Neuro-oncology. 67:167-176.

149. Park, J., Jeong, E., Choi, K., Kwon, D., Benveniste, E.N., and C. Choi. 2004. Reactive oxygen species mediate chloroquine-induced expression of chemokines by human astroglial cells. GLIA. 47:9-20.

150. Adamski, J., Ma, Z., Nozell, S., and E.N. Benveniste. 2004. 17β-estradiol inhibits class II MHC expression: Influence on histone modifications and CBP recruitment to the class II MHC promoter. Mol. Endocrinol. 18:1963-1974.

151. Kutsch, O., Levy, D.N., Bates, P.J., Decker, J., Kosloff, B.R., Shaw, G.M., Priebe, W., and E.N. Benveniste. 2004. Bis-Anthracycline antibiotics inhibit HIV-1 transcription. Antimicrobial Agents and Chemotherapy. 48:1652-1663.

152. Kim, S., Choi, K., Kwon, D., Benveniste, E.N., and C. Choi. 2004. Ubiquitin-proteasome pathway as a primary defender against TRAIL-mediated cell death. Cell. Mol. Life Sci. 61:1075-1081.

153. Ma, Z., Shah, R.C., Chang, M.J., and E.N. Benveniste. 2004. Coordination of cell signaling, chromatin remodeling, histone modifications and regulator recruitment in human MMP-9 gene transcription. Mol. Cell. Biol. 24:5496-5509.

154. Nozell, S., Ma, Z., Wilson, C., Shah, R., and E.N. Benveniste. 2004. Class II MHC transactivator (CIITA) inhibits matrix metalloproteinase-9 gene expression. J. Biol. Chem. 279:38577-38589.

155. Chen, S-H., and E.N. Benveniste. 2004. Oncostatin M: a pleiotropic cytokine in the central nervous system. Cytokine & Growth Factor Reviews. 15:379-391.

156. Ma, Z., Chang, M., Shah R., Adamski, J., and E.N. Benveniste. 2004. Brg-1 is required for maximal transcription of the human MMP-2 gene. J. Biol. Chem. 279:46326-46334.

157. Adamski, J., and E.N. Benveniste. 2005. 17β-estradiol activation of the c-Jun N-Terminal kinase pathway leads to down-regulation of Class II MHC expression. Mol. Endocrinol. 19:113-124.

158. Jones, J., Kosloff, B.R., Benveniste, E.N., G. M. Shaw and O Kutsch. 2005. Amphotericin-B mediated reactivation of latent HIV-1 infection. Virology. 331:106-116.

159. Benveniste, E.N., and D. Benos. 2005. Astrocyte Immunobiology. In: The Neurology of AIDS, Second Edition. H. E. Gendelman, I. Grant, I. P. Everall, S.A. Lipton, S. Swindells, (eds). Oxford University Press, pp. 211-223.

160. Choi, J., Choi, K., Benveniste, E.N., Hong, Y-S., Lee, J-H., Kim, J., and K. Park. 2005. Bcl-2 promotes invasion and lung metastasis by inducing matrix metalloproteinase-2. Cancer Res. 65:5554-5560.

161. Qin, H., Wilson, C.A., Lee S.J., Zhao, E., and E.N. Benveniste. 2005. LPS induces CD40 gene expression through the activation of NF-κB and STAT-1α in macrophages and microglia. Blood. 106: 3114-3122.

162. Ma, Z., Chang, M., Shah, R.C., and E.N. Benveniste. 2005. Interferon-γ activated STAT-1α suppresses MMP-9 gene transcription by sequestration of the co-activator CBP/p300. J. Leuk. Biol. 78:515-523.

Benveniste

163. Chen, S-H., Gillespie, G.Y., and E.N. Benveniste. 2006. Divergent effects of Oncostatin M on astroglioma cells: Influences on cell growth and expression of matrix metalloproteinases. GLIA. 53:191-200.

164. Ransohoff, R.M., and E.N. Benveniste. 2006. Editors. Cytokines and the CNS: Second Edition. CRC Press. Boca Raton, Florida.

165. Qin, H., Wilson, C.A., Lee, S-J, and E.N. Benveniste. 2006. IFN-β-induced SOCS-1 negatively regulates CD40 gene expression in macrophages and microglia. FASEB J. 20:985-987.

166. Nozell, S., Laver, T., Patel, K., and E.N. Benveniste. 2006. Molecular mechanisms underlying IFN-β mediated inhibition of IL-8 gene expression in astrogliomas. J. Immunol. 177:822-830.

167. Qin, H., Wilson, C.A., Baker, B.J., Zhao, X., and E.N. Benveniste. 2006. IL-10 inhibits LPS-induced CD40 gene expression through induction of SOCS-3. J. Immunol. 177:7761-7771.

168. Choi, Y-H., Bernardi, R., Pandolfi, P-P., and E.N. Benveniste. 2006. The promyelocytic leukemia protein functions as a negative regulator of IFN-γ signaling. Proc. Natl. Acad. U.S.A. 103:18715-18720.

169. Lee, S-J., Qin, H., and E.N. Benveniste. 2007. Simvastatin inhibits IFN-γ-induced CD40 gene expression by suppressing STAT-1α. J. Leuk. Biol. 82:436-437.

170. Qin, H., Roberts, K.L., Niyongere, S.A., Cong, Y., Elson, C.O., and E.N. Benveniste. 2007. Molecular mechanism of LPS-induced SOCS-3 gene expression in macrophages and microglia. J. Immunol. 179:5966-5976.

171. Benveniste, E.N. 2007. Intracellular signaling cascades in glia. In: Immune and Glial Regulation of Pain. L. Watkins, J. DeLeo, L. Sorkin (eds). ISAP Press. pgs. 43-63.

172. Benveniste, E.N., and H. Qin. 2007. Type I Interferons as anti-inflammatory mediators. Science STKE. 416:70, (DOI: 10.1126/stke.4162007pe70).

173. Zhao, S., Nozell, S., Ma, Z., and E.N. Benveniste. 2007. The ISGF3 complex mediates the inhibitory effect of IFN-β on MMP-9 expression. FEBS J. 274:6456-6468.

174. Laver, T., Nozell, S. E., and E.N. Benveniste. 2008. Interferon-β-mediated inhibition of IL-8 expression requires the ISGF3 components STAT-1, STAT-2 and IRF-9. J. Interferon and Cytokine Res. 28:13-23.

175. Brantley, E.C., and E.N. Benveniste. 2008. STAT-3: A molecular hub for signaling pathways in gliomas. Mol. Cancer Res. 6:675-684.

176. Lee, S-J., Qin, H., and E.N. Benveniste. 2008. The IFN-γ-induced transcriptional program of the CIITA gene is inhibited by statins. Eur. J. Immunol. 38:2325-2336.

177. Baker, B.J., Qin, H., and E.N. Benveniste. 2008. Regulation of SOCS-3 gene expression in astrocytes by Oncostatin M. GLIA. 56:1250-1262.

178. Kwon, D., Choi, K., Choi, C., and E.N. Benveniste. 2008. Hydrogen peroxide enhances TRAIL-induced death through up-regulation of DR5 in human astrocytic cells. Biochem. Biophys. Res. Commun. 372:870-874.

179. Brantley, E.C., Nabors, L.B., Gillespie, G.Y., Choi, Y-H., Palmer, C., Harrison, K., Roarty, K., and E.N. Benveniste. 2008. Loss of PIAS3 expression in glioblastoma multiforme tumors: Implications for STAT-3 activation and gene expression. Clin. Cancer Research. 14:4694-4704.

180. Qin, H., Niyongere, S.A., Lee, S-J., Baker, B.J., and E.N. Benveniste. 2008. Expression and functional significance of SOCS-1 and SOCS-3 in astrocytes. J. Immunol. 181:3167-3176.

181. Zhao, X., and E.N. Benveniste. 2008. Transcriptional activation of human matrix metalloproteinase-9 gene expression by multiple coactivators. J. Mol. Biol. 383:945-956.

182. Nozell, S., Laver, T., Moseley, D., Nowoslawski, L., DeVos, M., Atkinson, G.P., Harrison, K., Nabors, L.B., and E.N. Benveniste. 2008. The ING4 tumor suppressor attenuates NF-κB activity at the promoter of target genes. Mol. Cell Biol. 28:6632-6645.

183. Kim, J.-H., Choi, C., Benveniste, E.N. and D. Kwon. 2008. TRAIL induces MMP-9 expression via ERK activation in human astrocytoma cells. Biochem. Biophysical Res. Comm. 377:195-199.

184. Laver, T., Nozell, S., and E.N. Benveniste. 2009. The NF-κB pathway in glioblastoma: Implications for apoptotic and inflammatory responses and exploitation for therapy. In: CNS Cancer Models, Prognostic Factors, Targets and Therapeutic Approaches. Editor, E.G. Van Meir. Humana Press (Springer). Chapter 42. 1011-1036.

185. Rege, T.A., Stewart, J. Jr., Dranka, B., Benveniste, E.N., Silverstein, R.L. and C.L. Gladson. 2009. Thrombospondin-1-induced apoptosis of brain microvascular endothelial cells can be mediated by TNF-R1. J. Cell. Physiol. 21:94-103.

186. Oh, J.W., Olman, M., and E.N. Benveniste. 2009. CXCL12-mediated induction of plasminogen activator

Benveniste

inhibitor-1 expression in human CXCR4 positive astroglioma cells. Biol. Pharm. Bull. 32:573-577. 187. Qin, H., Wang, L., Elson C.O., Niyongere, S.A., Lee, S-J., Maynard C.L., Weaver, C. T., Roarty K.P.,

Serra, R.A., Benveniste, E.N., and Y. Cong. 2009. TGFβ promotes Th17 cell development through inhibition of SOCS3. J. Immunol. 183:97-105.

188. Baker, B.J., Akhtar, L.N., and E.N. Benveniste. 2009. SOCS1 and SOCS3 in the control of CNS immunity. Trends. Immunol. 30:392-400.

189. Atkinson, G.P., Nozell, S.E., Harrison, D.K., Stonecypher, M.S., Chen, D., and E.N. Benveniste. 2009. The prolyl isomerase Pin1 regulates the NF-κB signaling pathway and interleukin-8 expression in glioblastoma. Oncogene. 28:3735–3745.

190. Atkinson, G.P., Nozell, S.E., and E.N. Benveniste. 2010. NF-κB and STAT3 signaling in glioma: Targets for future therapies. Invited Review. Expert Rev Neurother. 10:575-586

191. Baker B.J., Park K.W., Qin H., Ma X., and E.N. Benveniste. 2010. IL-27 inhibits OSM-induced TNF-α and iNOS gene expression in microglia. GLIA. 58:1082-1093

192. Ma, X., Reynolds, S.L., Baker, B.J., Li, X., E.N. Benveniste, and H. Qin. 2010. Interleukin-17 enhancement of the IL-6 signaling cascade in astrocytes. J. Immunol. 184:4898-906

193. Akhtar, L. N., H. Qin, M. T. Muldowney, L. L. Yanagisawa, O. Kutsch, J. E. Clements, and E.N. Benveniste. 2010. Suppressor of Cytokine Signaling 3 inhibits antiviral IFN-β signaling to enhance HIV-1 replication in macrophages. J. Immunol. 185:2393-2404.

194. Lai Y-J., Lin V., Zheng Y., E.N. Benveniste, and Lin F-T. 2010. The adaptor protein TRIP6 antagonizes Fas-induced apoptosis but promotes its effect on cell migration. Mol. Cell Biol. 30:5582-5596.

195. Feng, T., Cong, Y., Qin, H., Benveniste, E.N., and Elson, C. O. 2010. Generation of mucosal dendritic cells from bone marrow reveals a critical role of retinoic acid. J. Immunol. 185:5915-5925.

196. Akhtar, L. N., and E. N. Benveniste. 2011. Viral exploitation of host SOCS protein functions. Invited Review. J. Virol. 85:1912-1921.

197. Zhao X., Laver T., DeVos A., Twitty G., DeVos M., Hong, S.W., E.N. Benveniste, and Nozell S.E. 2011. An NF-κB p65 cIAP2 link is necessary for mediating apoptotic resistance to TNF-α in gliomas. J. Neuro- Oncol. 102:367-381.

198. Zheng, Y., Qin, H., Frank, S.J. Deng, L., Litchfield, D. W., Tefferi, A., Pardanani, A., Lin, Fang-Tsyr, Li, J., Sha, B., and E.N. Benveniste. 2011. A CK2-dependent mechanism for activation of the JAK-STAT signaling pathway. BLOOD 118:156-166.

199. Feng, T., Qin, H., Wang, L., Benveniste, E.N., Elson, C.O., and Y. Cong. 2011. Th17/IL-17 induces colitis and promotes Th1 responses through induction of innate cell IL-12 and IL-23 production. J. Immunol. 186:6313-6318.

200. Benveniste, E.N., Akhtar, L.N., and B.J. Baker. 2011. Astrocytes. In “The Neurology of AIDS” Third Edition 3:2.3,119-130.

201. Meares, G.P., K.J. Hughes, A. Naaz, F.R. Papa, F. Urano, P.A. Hansen, E.N. Benveniste, and J.A. Corbett. 2011. IRE1-dependent activation of AMPK in response to Nitric Oxide. Mol. Cell Biol. 31:4286-4297.

202. Song, D.E., Kim, H.J., Lim, S.Y., Lee, S-H., Kang, J.L., Benveniste, E.N., and Y-H., Choi. 2011. Loss of the promyelocytic leukemia protein in gastric cancer: Implications for IP-10 expression and tumor-infiltrating lymphocytes. PLoS One. 6:26264-26275.

203. McFarland, B.C., Ma, J.Y., Langford, C.P., Gillespie, G.Y., Yu, H., Zheng, Y., Nozell, S.E., Huszar, D., and E.N. Benveniste. 2011. Therapeutic potential of AZD1480 for the treatment of human glioblastoma. Mol. Cancer Therapeutics. 10:2384-2393.

204. Qin, H., and E.N. Benveniste. 2012. ELISA methodology to quantify astrocyte production of cytokines/chemokines in vitro. In “Methods in Molecular Biology; Astrocytes: Methods and protocols”. 814:235-249

205. Meares, G.P., Ma, X., Qin, H., and E.N. Benveniste. 2012. Regulation of CCL20 expression in astrocytes by IL-6 and IL-17. GLIA. 60:771-781.

206. Qin, H., Yeh, W.-I., De Sarno, P., Holdbrooks, A. T., Liu, Y., Muldowney, M. T., Reynolds, S. L., Yanagisawa, L. L., Fox, T. H. I., Park, K., Harrington, L. E., Raman, C., and Benveniste, E. N. (2012) Signal transducer and activator of transcription-3/suppressor of cytokine signaling-3 (STAT3/SOCS3) axis in myeloid cells regulates neuroinflammation. Proc Natl Acad Sci U. S. A. 109:5004-5009.

207. Qin, H., Holdbrooks, A.T., Liu, Y., Reynolds, S.L., Yanagisawa, L.L. and E.N. Benveniste. 2012. SOCS3 deficiency promotes M1 macrophage polarization and inflammation. J. Immunol. 189:3439-48.

208. Park, K., Nozell, S.E., and E.N. Benveniste. 2012. Protective role of STAT3 in NMDA-induced neuronal

Benveniste

death: Negative regulatory effect of SOCS3. PLoS One. 7(11): e50874. 209. Meares, G.P., Qin, H., Liu, Y., Holdbrooks, A.T. and Benveniste, E.N. 2013. AMP-activated protein

kinase restricts IFN-γ signaling. J. Immunol. 190:372-380. 210. McFarland, B.C., Gray, G.K., Nozell, S.E., Hung, S.W. and E.N. Benveniste. 2013. Activation of the

NF-κB pathway by the STAT3 inhibitor JSI-124 in human glioblastoma cells. Mol. Cancer Res. 11:494-505.

211. Zheng, Y., McFarland, B., Drygin, D., Yu, H., Bellis, S.L., Kim, H., Bredel, M. and Benveniste E.N. 2013. Targeting protein kinase CK2 suppresses prosurvival signaling pathways and growth of glioblastoma. Clin. Cancer Res. 19:6484-6494.

212. McFarland, B.C., Hong, S. W., Rajbhandari, R., Twitty, G.B., Gray, G.K., Yu, H., E.N. Benveniste, Nozell, S.E. 2013. NF-κB induced IL-6 ensures STAT3 activation and tumor aggressiveness in glioblastoma. PLoS One. 8(11):e78728.

213. Liu, Y., Holdbrooks, A., De Sarno, P., Rowse, A.L., Yanagisawa, L.L., McFarland, B., Harrington, L.E., Raman, C., Sabbaj, S., E.N. Benveniste and Qin, H. 2014. Therapeutic efficacy of suppressing the JAK/STAT signaling pathway in multiple models of experimental autoimmune encephalomyelitis. J. Immunol. 192:59-72

214. Benveniste, E.N., Liu, Y., McFarland, B.C. and H. Qin. 2104. Involvement of the JAK/STAT signaling pathway in Multiple Sclerosis and the animal model of experimental autoimmune encephalomyelitis. Invited Review. J. Interferon and Cytokine Res. 34(8):577-588

215. Meares, G.P., and E.N. Benveniste. 2014. Inflammation and the pathophysiology of astrocytes in neurodegenerative diseases. In Neuroinflammation and Neurodegeneration. P. Peterson and M. Toborek, Editors. Springer Press. Pages 61-80.

216. Benveniste, E.N. 2014. Cytokines. In Encyclopedia of Neurological Sciences. M. Aminoff and R. Daroff, Editors. Academic Press.

217. Gray, G.K., McFarland, B. C., Rowse, A. L., Gibson, S. A., and Benveniste, E.N. 2014. Therapeutic CK2 inhibition attenuates diverse prosurvival signaling cascades and deceases cell viability in human breast cancer cells. Oncotarget. 5(15):6484-96.

218. Meares, G.P., Liu, Y., Rajbhandari, R., Qin, H., Nozell, S., Mobley, J., Corbett, J.A., and E.N. Benveniste. 2014. PERK dependent activation of JAK1 and STAT3 contributes to ER stress induced inflammation. Mol Cell Biol. 34(20):3911-3925.

219. Gray, G.K., McFarland, B. C., Nozell, S., and Benveniste, E.N. 2014. NF-κB and STAT3 in glioblastoma: Therapeutic targets coming of age. Invited Review Article. Expert Rev. Neurother. 14(11):1293-1306.

220. Benveniste, E.N., Gray, G.K., and McFarland, B.C. 2015. Protein kinase CK2 and dysregulated oncogenic inflammatory signaling pathways. In: Protein Kinase CK2 Cellular Function in Normal and Disease States. Editors: K. Ahmed, O-G Issinger and R. Szyszka. Springer Press. pgs. 259-280.

221. Basu, R., Whitley, S.K., Bhaumik, S., O’Quinn, D.B., Schoeb, T.R., Benveniste, E.N., Pear, W.S., Hatton, R.D., and Weaver, C.T. 2015. IL-1 signaling modulates STAT activation to antagonize retinoic acid signaling in the control of Th17-iTreg developmental balance. Nat. Immunol. 16:286-295.

222. Yu, H., Liu, Y., McFarland, B.C., DeShane, J.S., Hurst, D.R., Ponnazhagen, S., Benveniste, E.N., and H. Qin. 2015. SOCS3 deficiency in myeloid cells promotes tumor development: Involvement of STAT3 activation and myeloid-derived suppressor cells. Cancer Immunol. Res. 3(7):727-740.

223. Liu, Y., Holdbrooks, A.T., Meares, G.P., Buckley, J. A., Benveniste, E.N., and Qin, H. 2015. Preferential recruitment of neutrophils into the cerebellum and brainstem contributes to the atypical EAE phenotype. J. Immunol. 195(3):841-852.

224. McWilliams, I.L., Rajbhandari, R., Nozell, S., Benveniste, E.N., and Harrington, L. E. 2015. STAT4 controls GM-CSF production by both Th1 and Th17 cells during EAE. J. Neuroinflamm. 12:128-140.

225. Rajbhandari, R., McFarland, B.C., Patel, A., Bredel, M., Berbari, N.F., Robert, S., Marks, M.P., Meares, G.P., Sinha,T., Smith,S., Benveniste, E.N., and Nozell, S.E. 2015. Loss of tumor supressor microRNA-31 at chromosomal locus 9p21.3 enhances TRADD/NF-κB signaling in glioblastoma. Oncotarget. 6(19):17805-17816.

226. McFarland, B.C., Marks, M.P., Rowse, A.L., Fehling, S.C., Gerigk, M., Qin, H., and Benveniste, E.N. 2016. Loss of SOCS3 in myeloid cells prolongs survival in a syngeneic model of glioblastoma. Oncotarget. 7(15):20621-20635.

227. Qin, H., Buckley, J.A., Li, X., Liu, Y., Fox, T.H., Meares, G.P., Hao, Y., Yan, Z., Harms, A.S., Li, Y., Standaert, D. G., and Benveniste, E.N. 2016. Inhibition of the JAK/STAT pathway protects against α-synuclein-induced neuroinflammation and dopaminergic neurodegeneration. J. Neurosci. 36(18): 5144-5159.

Benveniste

228. Liu, Y., Gibson, S.A., Benveniste, E.N., and Qin, H. 2016. Opportunities for translation from the bench: Therapeutic intervention of the JAK/STAT pathway in neuroinflammatory diseases. Invited Review, Crit. Rev. Immunol. 35(6): 505-527.

229. Guthrie, L.N., Abiraman, K., Gibson, S.A., McFarland, B.C., Rajbhandari, R., Rowse, A.L., Benveniste, E.N., and Meares, G.M. 2016. Attenuation of PERK signaling controls ER stress induced inflammation without compromising immunological responses. J. Biol Chem. 291(30):15830-15840.

230. Park, K.W., Lin, C-Y., Benveniste, E.N., and Lee, Y-S. 2016. Mitochondrial STAT3 is negatively regulated by SOCS3 and upregulated after spinal cord injury. Exp. Neurol. 284(Pt A):98-105.

231. Zhao, J., Yu, H., Liu, Y., Gibson, S.A., Yan, Z., Xu, X., Gaggar, A., Li, P-K., Li, C., Wei, S., Benveniste, E.N., and Qin, H. 2016. Protective effect of suppressing STAT3 activity on LPS-induced acute lung injury. Am J Physiol Lung Cell Mol Physiol. 311(5):L868-L880.

232. Yan, Z., Gibson, S.A., Buckley, J.A., Qin, H., and E.N. Benveniste. 2016. Role of the JAK/STAT signaling pathway in regulation of innate immunity in neuroinflammatory disease. Invited Review. Clin Immunol. pii: S1521-6616(16)30449-1.

233. Lai, Y., Tsai, J., Tseng, Y., Wu, M., Liu, W., Lam, H., Yu, J., Nozell, S.E., and Benveniste, E.N. 2017. Small G proteins Rac GTPases regulate the maintenance of glioblastoma stem-like cells. Oncotarget. 75(15) S 4219-4237.

234. Rowse, A.L., Gibson, S.A., Meares, G.P., Rajbhandari, R., Nozell, S.E., Dees, K.J., Hjelmeland, A.B., McFarland, B.C., and Benveniste, E.N. 2017. Protein kinase CK2 is important for the function of glioblastoma brain tumor initiating cells. J. Neuro Oncol. 132(2):219-229.

235. Klein, R. S., Voskuhl, R., Segal, B. M., Dittel, B. N., Lane, T. E., Bethea, J. R., Carson, M. J., Colton, C., Rosi, S., Anderson, A., Piccio, L., Goverman, J. M., Benveniste, E. N., and Cross, A. H. 2017. Speaking out about gender imbalance in invited speakers improves diversity: an example in neuroimmunology. Nature Immunol. 18(5): 475-478.

236. Gibson, S.A., Yang, W., Yan, Z., Liu, Y., Rowse, A., Weinmann, A. S., Qin, H., and E.N. Benveniste. 2017. Protein kinase CK2 controls the fate between Th17 cell and regulatory T cell differentiation. J. Immunol. 198: 4244-4254.

237. Harms, A.S., Thome, A.D., Yan, Z., Schonhoff, A. M., Williams, G. P., Li, X., Liu, Y., Qin, H., Benveniste, E.N., and Standaert, D.G. 2018. Peripheral monocyte entry is required for alpha-Synuclein induced inflammation and neurodegeneration in a model of Parkinson disease. Exp. Neurol. 300:179-187.

238. Gibson, S. A., and E. N. Benveniste. 2018. Protein kinase CK2: An emerging regulator of immunity. Invited Review. Trends in Immunol. 39(2):82-85.

239. Meares, G.P., Rajbhandari, R., Gerigk, M., Tien, C-L., Chang, C., Fehling, S.C., Rowse, A., Mulhern, K.C., Gray, G.K., Berbari, N.F., Benveniste, E.N., and Nozell, S.E. 2018. MicroRNA-31 is required for maintaining astrocyte identity. Glia. 66(5):987-998.

240. Gibson, S. A., Yang, W., Yan, Z., Qin, H., and E.N. Benveniste. 2018. CK2 controls Th17 and regulatory T cell differentiation through inhibition of FoxO1. J. Immunol. 201 (2) 383-392.

241. Yan, Z., Yang, W., Parkitny, L., Gibson, S. A., Lee, K., Collins, F., DeShane, J., Cheng, W., Weinmann, A. S., Wei, H., Qin, H., and E. N. Benveniste. 2019. Deficiency of SOCS3 leads to brain-targeted EAE via enhanced neutrophil activation and production of reactive oxygen species. J. Clin. Invest. Insight. 4(9):e126520

242. McFarland, B.C. and E. N. Benveniste. 2019. Reactive astrocytes foster brain metastasis via STAT3 signaling. Invited Editorial. In Press . Ann. Transl. Medicine.

243. Zimmerman, K. A., Song, C. J., Lever, J. M., Crossman, D. K., Li, Z., Zhou, J., Crowley, M., Revell, D. Z., Giles, K., Gonzalez, N. M., Yan, Z., Shan, D., Benveniste, E. N., George, J. F., Mrug, M., and Yoder, B. K. 2019. Resident macrophage reprogramming after injury toward a juvenile state promotes renal cystic disease. Under Revision. J. Amer. Soc. Nephrol.

244. Kalinin, S., Meares, G. P., Lin, S. X., Pietruczyk, E. A., Lutz, S. E., Benveniste, E. N., and Feinstein, D. L. 2019. Liver kinase B1 depletion from astrocytes exacerbates disease in a mouse model of multiple sclerosis. Submitted.

245. Yang, W., Gibson, S.A., Yan, Z., Qin, H., and E. N. Benveniste. 2019. Protein kinase 2 (CK2) is required for CD4+ T-cell function in the pathogenesis of colitis. In preparation.

246. Yan, Z.*, Yang, W.*, Dean, M.N., Standaert, D.G., Cutter, G., Benveniste, E. N., and Qin, H. 2019. Immunologic dysfunction in CD4+ and CD8+ T-cells subsets in Parkinson’s disease. In preparation.

STUDENTS AND FELLOWS SUPERVISED:

Benveniste

Graduate Students Degree Year John R. Bethea 1988-Ph.D. Student in Cell Biology Graduated November 1991 J. Gavin Norris 1988-Ph.D. Student in Cell Biology Graduated July 1993 Il Yup Chung 1989-Ph.D. Student in Cell Biology Graduated May 1992 R. Brian Panek 1990-Ph.D. Student in Cell Biology Graduated August 1993 Jongbum Kwon 1990-Ph.D. Student in Cell Biology Graduated May 1995 Yi-Ju Lee 1991-Ph.D. Student in Cell Biology Graduated June 1996 Protul Shrikant 1991-Ph.D. Student in Cell Biology Graduated October 1995 Mary Ballestas 1992-Ph.D. Student in Cell Biology Graduated May 1997 Wolfgang Rohn 1994-Ph.D. Student in Physiology & Biophysics Graduated January 1998 Kumar Pandya 1994-1996 Ph.D. Student in Cell Biology Sung-Joong Lee 1995-Ph.D. Student in Cell Biology Graduated August 1999 Hongwei Qin 1996-Ph.D. Student in Cell Biology Graduated September 1999 Nicholas Van Wagoner 1996-Ph.D. Student in Cell Biology Graduated November 1999 Vincent Nguyen 1996-Ph.D. Student in Cell Biology Graduated February 2000 George O'Keefe 1997-Ph.D. Student in Cell Biology Graduated January 2001 Yuanshu Dong 1997-Ph.D. Student in Cell Biology Graduated December 2000 Pavle Repovic 1999-Ph.D. Student in Cell Biology (MSTP) Graduated September 2002 Jeff Ma 1999-Ph.D. Student in Cell Biology Graduated October 2002 Kathryn Drabik 2000-Ph.D. Student in Cell Biology (MSTP) Graduated June, 2001 (Masters) Paul (Guy) Melvin 2000-Ph.D. Student in Cell Biology Graduated July, 2002 (Masters) Jill Adamski 2001-Ph.D. Student in Cell Biology (MSTP) Graduated September 2004 Duane Wesemann 2001-Ph.D. Student in Cell Biology (MSTP) Graduated September 2003 Emily Brantley 2003-Ph.D. Student in Cell Biology Graduated December 2007 Mi Jung Chang 2003-Ph.D. Student in Cell Biology Graduated April, 2005 (Masters) Sun Jung Lee 2003-Ph.D. Student in Cell Biology Graduated February 2008 Travis Laver 2004-Ph.D. Student in Cell Biology Graduated March 2008 Dorothy Balshuweit 2004-2006 Student in Cell Biology Xueyan (Snow) Zhao 2004-Ph.D. Student in Cell Biology Graduated May 2008 Brandi Baker 2005-Ph.D. Student in Cell Biology Graduated October 2009 George Atkinson 2005-Ph.D. Student in Cell Biology (MSTP) Graduated December 2009 Lisa Nowoslawski 2006-Ph.D. Student in Cell Biology Graduated January 2010 Ying Zheng 2007-Ph.D. Student in Cell Biology Graduated March 2010 George Twitty 2008-2010 Ph.D. Student in Cell Biology Yudong Liu 2011-Ph.D. Student in Immunology Theme Graduated March 2015 Hao Yu 2011-Ph.D. Student in Cell, Molecular and

Developmental Biology Theme Graduated July 2015

Kenneth Gray Sara Gibson

2013-Master’s Program 2013-Ph.D. Student in Immunology Theme

Graduated April 2014 Graduated August 2017

Zhaoqi Yan 2015-Ph.D. Student in Immunology Theme Graduate Student Laboratory Rotation Advisor Martha Land 1987-Neurosciences John R. Bethea 1987-Neurosciences J. Gavin Norris 1987-Neurosciences David Ansardi 1988-Cellular and Molecular Biology Jane Dunlap 1988-Cellular and Molecular Biology Mary Williams 1988-Neurosciences Joseph Amman 1989-Cellular and Molecular Biology Carolyn Rogers 1989-Neurosciences Kelley Black 1990-Cellular and Molecular Biology R. Brian Panek 1990-Cellular and Molecular Biology Tae Ho Shin 1990-Cell Biology Yi-Ju Lee 1991-Cellular and Molecular Biology Protul Shrikant 1991-Cellular and Molecular Biology Mary Ballestas 1991-Cellular and Molecular Biology Stephen Stray 1992-Cellular and Molecular Biology Melissa Kearns 1993-Cellular and Molecular Biology Marie Lacy 1993-Cellular and Molecular Biology Jacinda Sampson 1993-MD/PhD Training Program Ira Blader 1993-Neurosciences Julie Koh 1993-Cellular and Molecular Biology Kumar Pandya 1993-Cellular and Molecular Biology Wook Joon Chung 1993-Neurosciences Xiaosi Han 1994-Neurosciences

Benveniste

Rotem Elgavish 1994-MD/PhD Training Program Sung Joong Lee 1994-Cellular and Molecular Biology Cynthia Vied 1995-Cellular and Molecular Biology Zucheng Ye 1995-Neurosciences Vince Nguyen 1995-Cell Biology Denise Kaminski 1995-Cellular and Molecular Biology Xinmin Li 1996-Neurosciences Hongwei Qin 1996-Cell Biology Nicholas Van Wagoner 1996-Cellular and Molecular Biology George O’Keefe 1996-Cellular and Molecular Biology Yuanshu Dong 1997-Cellular and Molecular Biology Xiaoyong Yang 1997-Cellular and Molecular Biology Yinong Zong 1998-Neurosciences Erin Rogers 1998-Cellular and Molecular Biology Pavle Repovic 1998-MD/PhD Training Program John Bates 1998-Cellular and Molecular Biology Jeff Ma 1999-Neurosciences Jill Adamski 1999-MD/PhD Training Program Kathryn Drabik 1999-MD/PhD Training Program Yuliang Xu 2000-Cellular and Molecular Biology Jiawei Ye 2000-Neurosciences Paul Melvin 2000-Cellular and Molecular Biology Yongsheng Xu 2001-Neurosciences Ryan Schulz 2001-Cellular and Molecular Biology Duane Wesemann 2001-MD/PhD Training Program Wenlong Han 2001-Cellular and Molecular Biology Eric Helton 2002-Cellular and Molecular Biology Kaihong Mi 2002-Neurosciences Paul Harms 2002-MD/PhD Training Program Michael McFerrin 2002-Cellular and Molecular Biology Michelle Amaral 2002-Cellular and Molecular Biology Emily Brantley 2003-Cellular and Molecular Biology Travis Laver 2003-Cellular and Molecular Biology Xueyan Zhao 2004-Cellular and Molecular Biology Dorothy Balshuweit 2004-Cellular and Molecular Biology George Atkinson 2004-MD/PhD Training Program Ying Zheng 2005-Cellular and Molecular Biology Jilllian Adams 2005-Cellular and Molecular Biology Brandi Baker 2005-Neurosciences Changhoon Lee 2006-Neurosciences Lisa Nowoslawski 2006-MD/PhD Training Program Rachel Gill 2006-2007 Cellular and Molecular Biology George Twitty 2008-Cellular and Molecular Biology Jessica Chancey 2009-Cellular and Molecular Biology Stephanie Easter 2009-Cellular and Molecular Biology Ha-Ram Cha 2010-Cancer Biology Program Sini Nwaboi 2010-MD/PhD Training Program Hao Yu 2011-Cell, Molecular and Developmental Biology Program Yudong Liu 2011-Immunology Program Boyoung Shin 2012-Immunology Program Sara Gibson 2012-Immunology Program Cathy Sung 2013-Microbiology Program Kyle Brawner 2013-Microbiology Program Kavitha Abiraman 2013-Neurosciences Program Kelly Kreitzburg 2014-Cancer Biology Program Emily Thompson 2014-Cell, Molecular and Developmental Biology Program Kaitlyn Dorsett 2014-Cancer Biology Program Samuel Fehling 2014-Cancer Biology Program Zhaoqi Yan 2015-Immunology Program Brandon Pope 2015-MD/Ph.D. Training Program Steven Gragg 2015-MD/Ph.D. Training Program Vishal Sharma 2016-Immunology Program Nathalia Melo 2017-Biochemistry Program Joy Shepard 2018-Neurosciences Program Member of Ph.D. Dissertation Committees Judith Baxter Department of Physiology and Biophysics, Graduated 1991

Benveniste

Naimin Wei Department of Physiology and Biophysics, Graduated 1992 James Nesbitt Department of Cell Biology, Graduated 1993 David Wilson Department of Cell Biology, Graduated 1998 Yuexia Li Department of Microbiology, Graduated 1992 Pamela Kozlowski Department of Microbiology, Graduated 1997 Tae Ho Shin Department of Cell Biology, Graduated 1994 Joe Amann Department of Cell Biology, Graduated 1997 Jialing Xiang Department of Cell Biology, Graduated 1996 Youngsuk Oh Department of Physiology and Biophysics, Graduated 1993 Yang Wang Department of Cell Biology, Graduated 1994 John Easton Department of Cell Biology, Graduated 1997 Brent Limbaugh Department of Microbiology, Graduated 1997 Nancy Veyna Department of Cell Biology, Graduated 1996 Chen Dong Department of Microbiology, Graduated 1996 Xuefen Huang Department of Microbiology, Graduated 1995 Mary Tucker Department of Cell Biology, Graduated 1995 Becky Schwibert Department of Comparative Medicine, Graduated 1997 Sossiena Demissie Department of Microbiology, Graduated 1996 Andrew Hurwitz Department of Pathology, Albert Einstein School of Medicine, Graduated 1994 Scott Drouin Department of Microbiology, Graduated 1997 Jenny Zhou Department of Cell Biology, Graduated 1997 Marc Daniels Department of Cell Biology, Graduated 1996 Mark Roos Department of Cell Biology, Graduated 1997 Eok-Soo Oh Department of Cell Biology, Graduated 1997 Zhiyong Liu Department of Cell Biology, Graduated 1997 Brian Kearns Department of Cell Biology, Graduated 1997 Dongyan Wang Department of Cell Biology, Graduated 1997 Zhixin (Jason) Zhang Department of Cell Biology, Graduated 1997 Holly Patton Department of Physiology and Biophysics, Graduated 1999 Liliana Soroceanu Department of Neurobiology, Graduated 1999 Anne Lynn Bradford Department of Physiology and Biophysics, Graduated 1999 Heng Xie Department of Pathology, Graduated 1998 John West Department of Microbiology, Graduated 2000 Inn-Oc Han Department of Cell Biology, Graduated 1997 Andrea Wolf Department of Microbiology, Graduated 2000 Melissa Kearns Department of Cell Biology, Graduated 1999 Kaihong Su Department of Cell Biology, Graduated 1998 Ira Blader Department of Cell Biology, Graduated 1998 Wen Xie Department of Cell Biology, Graduated 1997 Laura Fraser Cotlin Department of Cell Biology, Graduated 2000 Liang Liang Department of Cell Biology, Graduated 1999 Sung-Oh Kim Department of Cell Biology, Graduated 1999 Sunghyun Kang Department of Cell Biology, Graduated 2000 Brian Sims Department of Cell Biology, Graduated 1998 Denise Kaminski Department of Microbiology, Graduated 2002 Stacie Propst Department of Physiology and Biophysics, Graduated 2000 Young-Mi Go Molecular and Cellular Pathology, Graduated 2000 Maria Poczatek Molecular and Cellular Pathology, Graduated 2001 Min Fang Department of Cell Biology, Graduated 1998 Natasha Browner Department of Pharmacology, Graduated 2004 Yasheng Gao Department of Cell Biology, Graduated 2001 Zhigang Xie Department of Cell Biology, Graduated 2001 Yue Zhang Department of Cell Biology, Graduated 2001 KeriLyn Roberts Department of Microbiology, The University of Texas Health Science Center of

San Antonio, Graduated 2000 Mee Jeon Roh Department of Cell Biology, Graduated 2001 Erin Rogers Department of Cell Biology, Graduated 2004 Yue Wang Department of Microbiology, Graduated 2002 Kai He Department of Cell Biology, Graduated 2004 Fengxue Zhang Department of Cell Biology, Graduated 2003 Kevin Huang Department of Physiology/Biophysics, Graduated 2005 Daniel Greene Department of Cell Biology, Graduated 2004 Ssang-Taek Lim Department of Cell Biology, Graduated 2003 Kim Loesch Department of Cell Biology, Graduated 2006 Ligong Chen Department of Cell Biology, Graduated 2003 Tanya Rege Department of Cell Biology, Graduated 2005, MSTP Program Constance Fears Department of Cell Biology, Graduated 2005

Benveniste

Amish Shah Department of Physiology/Biophysics, Graduated 2006 Youngjin Lei Department of Neurobiology, Graduated 2006 Yun-Ju Lai Department of Cell Biology, Graduated 2007 Marcus Debiasi Department of Pathology, Graduated 2006 Yawar Qadri Department of Physiology/Biophysics, Graduated 2009, MSTP Program Brandon Beagle Department of Cell Biology, Graduated 2010 Ling Tian Department of Cell Biology, Graduated 2010 Yun Kyung Lee Department of Microbiology, Graduated 2009 Anand Balasubramani Department of Microbiology, Graduated 2010 Dongmei Su Department of Cell Biology, Graduated 2010 Rachel Gill Department of Cell Biology, Graduated 2011 Amanda Swindall Department of Physiology/Biophysics, Graduated 2012 Shuwen Cao Department of Genetics, Graduated 2011 Kelly Dunham Department of Neurobiology, Graduated 2011 Kate Kosmac Department of Microbiology, Graduated 2013 Victor Lin Department of Cell Biology, Graduated 2011, MSTP Program Wen-I Yeh Department of Cell Biology, Graduated 2013 John Jarboe Department of Biochemistry & Molecular Genetics, Graduated 2013,

MSTP Program Don McGuire Department of Microbiology, Graduated 2014 Robert Flynn Department of Microbiology, Graduated 2011 Amber Buel Department of Microbiology, Graduated 2013 Rachel Therese Center for Neuroscience, University of Melbourne, Graduated 2013 Heather Allen Department of Neurobiology, MSTP Program, Graduated 2016 Ian McWilliams Department of Cell, Developmental and Integrative Biology (CDIB), Graduated 2015 Hao Li Department of Microbiology, Graduated 2014 Sini Nwaobi Department of CDIB, MSTP Program, Graduated 2013 Tyrel Smith Immunology Thematic Program, Graduated 2015 Carson Moseley Department of Pathology, MSTP Program, Graduated 2016 Daniel Ditoro Department of Pathology, MSTP Program, Graduated 2017 Scarlett Evonuk Neuroscience Thematic Program, Graduated 2016 Aaron Thome Genetics Thematic Program, Graduated 2016 Mark Mohle Neuroscience Thematic Program, Graduated 2015 Cheng (Jack) Song CMDB Thematic Program-Graduated 2017 Hawley Pruitt Cancer Biology Thematic Program, Graduated 2017 Andrew Holdbrook Pathobiology of Disease Thematic Program, Graduated 2018 Nathan Boyd Immunology Thematic Program, Graduated 2017 Ann Hanna Cancer Biology Thematic Program, Graduated 2018 Aubrey Schonhoff Neuroscience Thematic Program Ashlyn Anderson Immunology Thematic Program Zhang Li CMBD Thematic Program Dominique Hinshaw Cancer Biology Thematic Program Medical Students Frank Thomas, M.D. 1987 Alyssa T. Reddy, M.D. 1990 John Waits 1997 Shilpa Reddy 2009 Jimmy Ma 2010, 2011 Nick Scalon 2012 Margaret Marks 2013, 2014 Ashish Patel 2013 Cherie Mulhern 2014 Taylor Pickens 2014, 2015 High School Students Shanae Windham 1992-Fairfield High School Eynav Elgavish 1992-Indian Springs High School Wei Zhou 1995, 1996-Vestavia Hills High School George Atkinson 1999-Vestavia Hills High School Marijke DeVos 2006-Altamont School Julia Massey 2007-Mountain Brook High School Annelise DeVos 2008-Altamont School Sarah Paul 2009-Altamont School Sidni Smith 2013-Ramsey Hill School Richard Fu 2016, 2017-Vestavia Hills High School

Benveniste

Undergraduate Students Alice Chen 1987, 1988 - Medical Student, Stanford University Jenny Miller 1989 - Medical Student, UAB Michal Elovitz 1989 - Medical Student, Albert Einstein School of Medicine Robert Law 1993 - 1994; Honors Program, UAB George Atkinson 2000 - Vanderbilt University 2001 - Vanderbilt University 2002 - Vanderbilt University Reesha Shah 2002 - University of Alabama at Birmingham, Honors Program, EMSAP Program Nemil Shah 2003 - University of Alabama at Birmingham Kiran Patel 2004 - University of Alabama at Birmingham, Honors Program Alisha George 2005 - University of Alabama at Birmingham, Honors Program, EMSAP Program Marijke DeVos 2007, 2008, 2009 - Williams College John Ryan Colvin 2007, 2008 - Samford University Jordan Beard 2008 - Samford University Annelies DeVos 2009, 2010 - Washington University at St. Louis Tom Fox 2010, 2011 - Lehigh University Gary K. Gray 2011- University of Alabama at Birmingham, Science and Technology Honors Program M. Addison Powell 2011 - Boston College Bryan Kariuki 2011, 2012 - Vanderbilt University Elias Awad 2011- Vanderbilt University Thomas Rheaume 2012 - Emory University Eugene Wu 2013 - Vanderbilt University

Imani Alexander 2015 - University of Alabama at Birmingham, Science and Technology Honors Program Nathalia Melo 2015, 2016 - DePauw University Briania Smith 2017, 2018 - Lawson State Community College, Birmingham, AL Jack Stein 2018, 2019 - Vanderbilt University Lianna Zhou 2018, 2019 - UC Santa Barbara Jason Lee 2019- Vanderbilt University

Postdoctoral Fellows Maria Vidovic, Ph.D. 1989-1990 Professor Australian National University, Research School of Biological Sciences Canberra, Australia Il Yup Chung, Ph.D. 1992 Professor Dept. of Biochemistry 398, Daehak-dong, Ansan, Kyungki-do, 425791, S. Korea Scott Huneycutt, Ph.D. 1993-1995 Unknown Brian Panek, Ph.D. 1993-1994 High School Science Teacher New Jersey Joo Young Park, M.D. 1994-1996 Dean, School of Medicine Yonsei University Wonju, Korea Margaret Winkler, M.D. 1995-1997 Professor Department of Pediatrics University of Alabama at Birmingham Medical Director, PICU President, Children’s Hospital of Alabama Birmingham, AL Jongbum Kwon, Ph.D. 1995 Professor Division of Molecular Life Sciences Ewha Womans University

Benveniste

Seoul, Korea Paul Lyons, Ph.D., M.D. 1995-1997 Neurologist (Epilepsy) Virginia Brain and Spine Center Winchester, VA Protul Shrikant, Ph.D. 1995-1996 Senior Member, Professor Mayo Clinic Scottsdale, Arizona Sung Joong Lee, Ph.D. 1999-2000 Professor Seoul National University Seoul, Korea Jae Wook Oh, Ph.D. 1997-2002 Assistant Professor Chosun University Gwangju, Korea Yuanshu Dong, Ph.D. 2001-2001 Assistant Professor Department of Biochemistry and Molecular Biology Indiana University Indianapolis, Indiana Olaf Kutsch, Ph.D. 1998-2003 Professor Department of Medicine University of Alabama at Birmingham Birmingham, AL Chulhee Choi, M.D., Ph.D. 1999-2002 Professor and Chair Biomedical Imaging Center KAIST Seoul, Korea George O’Keefe, Ph.D. 2001-2001 Unknown Steve Pedrini, Ph.D. 2000-2002 Research Associate Department of Neurosciences Thomas Jefferson Medical School Philadelphia, PA Vince Nguyen, Ph.D. 2000-2002 Cardiologist Friendswood, Texas Jinseu Park, Ph.D. 2001-2002 Professor (Sabbatical) Department of Genetic Engineering Hallym University, Republic of Korea Susan Nozell, Ph.D 2002-2006 Associate Professor Department of Radiation Oncology University of Alabama at Birmingham Birmingham, AL Daeho Kwon, Ph.D. 2002-2003 Assistant Professor Ewha Women’s University Seoul, Korea Daniel Chen, M.D., Ph.D. 2002-2005 Neurology Resident LSU, Shreveport Shreveport, Louisiana Eduardo Broitman, M.D. 2002-2004 Private Practice, Chile Zhendong Ma, M.D., Ph.D. 2002-2004 Psychiatrist Seattle, Washington

Benveniste

YounHee Choi, M.D., Ph.D. 2004-2007 Professor Ewha Women’s University Seoul, Korea Mark Stonecypher, M.D., Ph.D. 2007 Pathology Resident University of Pennsylvania Philadelphia, PA Xiangyu Ma, M.D. 2008-2010 Neurosurgery Resident Qinlu University, China Keun Park, Ph.D. 2009-2012 Postdoctoral Fellow Cornell University New York, NY Braden McFarland, Ph.D. 2009-2015 Instructor Department of Cell, Developmental and Integrative Biology University of Alabama at Birmingham Birmingham, AL Gordon Meares, Ph.D. 2010-2014 Assistant Professor West Virginia University Morgantown, WV Ying Zheng, Ph.D. 2010-2013 Postdoctoral Fellow NIH Bethesda, MD Jocelyn Lai, Ph.D. 2011-2012 Associate Professor Visiting Scholar Department of Life Science National Taiwan Normal University Taipei, Taiwan Amber Rowse, Ph.D. 2013-2015 Research Associate II Department of Immunotoxicology/Clinical Pathology Covance Laboratories, Inc. Madison, WI Jiping Zhao, Ph.D. 2014-2015 Visiting Scholar Kurt Zimmerman, Ph.D. 2016- Wei Yang, Ph.D. 2016- Luke Parkitny, Ph.D. 2017-2018 Hairong Wei, Ph.D. 2018- Weiping Wang, Ph.D. 2019- Visiting Scholar Junior Faculty Mentoring Committees: Chris Willey, M.D., Ph.D. Department of Radiation Oncology, 2008-2012 Jianmei Leavenworth, Ph.D. Department of Neurosurgery, 2016- Subhashini Bolisetty, Ph.D. Department of Medicine, Division of Nephrology, 2018- Coreen Schwartzlow, M.D. Department of Neurology, 2018- TEACHING RESPONSIBILITIES: Molecular and Cellular Neurobiology Course Lecture: “Glial Cell Structure and Function” 1987, 1988, 1989, 1992

Benveniste

Advanced Graduate Course in Neuroimmunology: Course Master Lectures: “Effects of Lymphokines on Glial Cells” “Secretion of Lymphokine-like Molecules from Glial Cells” “Antigen Presentation by Glial Cells” 1988 Cellular and Molecular Biology V: Immunology Lecture: “Neuroimmunobiology" 1990, 1991, 1992 Introduction to Neurobiology, Section 5: Neuroimmunology - Section Leader Lectures: “Introduction to Glial Cells and the Immune System” “Bidirectional Communication Between the Immune System and Central Nervous System” Fall 1990 Cellular and Molecular Biology IV: Cell Biology and Metabolism Lecture: “Cell Signaling: PKC” 1991 Advanced Graduate Course in Neuroimmunology Lectures: “Cytokines and Glial Cells” “Antigen Presentation by Astrocytes and Microglia” 1991, 1993 Cellular and Molecular Biology IV: Cell Biology Lectures: “Cell Signaling: Protein Kinase A” “Cell Signaling: Phosphoinositides/PKC” Winter 1992, 1993 Dental/Optometry Microscopic Anatomy Lectures/Labs: “Immune System Overview” “Thymus/Lymph Nodes” “Spleen/Tonsils” 1992, 1993, 1994 Medical Tissue and Cell Biology Lecture: “Signal Transduction, cAMP and PKA” 1993, 1994, 1995, 1996, 1997, 1998 “Signal Transduction: Cytokines and the JAK/STAT Pathway” 2001, 2002, 2004, 2005, 2006, 2007 Cellular and Molecular Biology IV: Cell and Developmental Biology Lectures: “Cell Signaling: PKA” “Cell Signaling: JAK/STAT Pathway” 1994, 1995, 1996, 1997, 1998, 1999, 2000, 2002, 2003, 2004, 2005, 2006, 2007, 2008, 2009, 2010, 2011, 2012, 2013, 2014, 2015, 2016, 2017, 2018, 2019 Molecular Mechanisms of Cellular Signal Transduction CB725 Lecture: “Molecular Mechanisms of Cytokine Action” 1994 Cellular and Molecular Biology IV: Cell Biology - Course Master 1995, 1996, 1997, 1998, 1999 Neurobiology of Disease Lecture: “Inflammatory Diseases of the CNS” 1996, 1997, 1998, 1999, 2000, 2002, 2003, 2004, 2005 Medical Neuroscience Discussion Section: NeuroAIDS 1997 Molecular Physiology and Medicine: Fundamental Insights into Common Diseases Lecture: “Multiple Sclerosis” 1998

Benveniste

Molecular Biology of Cell Adhesion Lecture: “ICAM-1 and the Immune Response” 1998 Cellular and Molecular Neurobiology Lecture: “Cytokines in the Central Nervous System” 1998 Cell Biology and Physiology in Medicine 2001, 2002, 2003 Advanced Course in Brain Tumor Biology, Co-Course Master 2004, 2006, 2009 Fundamentals I Lecture: “The JAK/STAT Signaling Pathway” 2008, 2009, 2010, 2011, 2012, 2013, 2014, 2015 Grant Writing Course for Postdoctoral Scholars Lecture: Abstract, Specific Aims and Background/Significance 2008, 2012 Professional Development for Immunology Trainees, MIC 741 Lecture: “How To Be a Leader” 2013 Neuroscience Café Lecture: “Demystifying Multiple Sclerosis” 2018, 2019 Masters in Health Administration Students Lecture: “The Research Enterprise in the School of Medicine, UAB” 2018 Undergraduate Neuroscience Colloquium Lecture: “Role of Neuroinflammation in Multiple Sclerosis and Animal Models of MS” 2018

date: may 20, 2019 personal information etty (tika ......may 20, 2019 · etty (tika) benveniste,...

Documents